D:Coronary Heart Disease

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Disease Term
Synonyms Cardiac Hypertrophy, Cardiomyopathy, Congenital Heart Disease, CORONARY DISEASE, Coronary Diseases, CORONARY HEART DISEASE CHD, Coronary Heart Diseases, CORONARY HEART DISORDER, Coronary Heart Dysfunction, Coronary Heart Syndrome, CORONARY OCCLUSION
Documents 5508
Hot Single Events 200
Hot Interactions 156

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Coronary Heart Disease. They are ordered first by their relevance to Coronary Heart Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT344716 Binding of Hdl1 and Chdh 1 0.03 3.24 0 100.00
2 INT131353 Binding of Npr1 and Nppb 1 0.27 1.73 0.4 100.00
3 INT131356 Binding of Nppa and Npr1 1 0.27 1.73 0.4 100.00
4 INT318174 Binding of Crp and Xcl1 1 0.03 1.9 0.22 100.00
5 INT344722 Binding of Lig3 and Chdh 1 0.00 1.48 0 100.00
6 INT344717 Binding of Niacr1 and Hdl1 1 0.17 1.51 0 100.00
7 INT28705 F7 Negative_regulation of TFPI 1 0.02 0.66 0.06 99.92
8 INT131357 Agtr2 Regulation of Ren 1 0.04 0.88 0.27 99.76
9 INT267214 Hspb8 Negative_regulation of Cryab 1 0.32 1.56 0.06 99.72
10 INT342599 Binding of Fos and Jun 1 0.32 0.99 0.2 99.64
11 INT300310 Akt1 Regulation of Foxo3 1 0.21 1.5 0.06 99.60
12 INT242992 Binding of Agt and Ppara 1 0.20 1.44 0.42 99.60
13 INT304883 Agtr2 Positive_regulation of Agtrap 1 0.10 0.46 0.09 99.52
14 INT300309 Akt1 Regulation of Rorb 1 0.05 3.28 0.06 99.32
15 INT267216 Binding of Cryab and Hspb8 1 0.36 9.29 0 99.16
16 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39 99.16
17 INT239317 Egfl7 Positive_regulation of Hdl1 2 0.01 2.3 0.14 99.08
18 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78 99.08
19 INT304887 Agtr2 Positive_regulation of Positive_regulation of Mapk1 1 0.10 0.45 0.09 99.00
20 INT344709 Niacr1 Positive_regulation of Hdl1 1 0.32 2.74 0.46 98.76
21 INT304882 Agtr2 Positive_regulation of Mapk1 1 0.07 0.95 0.2 98.56
22 INT284142 ERAS Regulation of PAH 1 0.10 0.55 0.2 98.28
23 INT284138 ERAS Regulation of Positive_regulation of PAH 1 0.10 0.55 0.2 98.28
24 INT304886 Agtr2 Positive_regulation of Ros1 1 0.03 0.45 0.09 98.24
25 INT126550 Agt Positive_regulation of Gene_expression of Nsfl1c 1 0.39 1.07 0.26 98.00
26 INT126548 Negative_regulation of Agt Positive_regulation of Nfkb1 1 0.29 0.99 0.25 97.96
27 INT267215 Binding of Cryab and Hspb1 1 0.25 7.19 0 97.92
28 INT228984 CRP Positive_regulation of IL6 2 0.63 0.99 0.17 97.88
29 INT293712 Binding of Adra2a and Atl1 1 0.06 0.83 0.15 97.60
30 INT126547 Agt Positive_regulation of Nfkb1 1 0.46 0.99 0.25 97.56
31 INT126553 Agt Positive_regulation of Nfkb1 1 0.06 0.99 0.25 97.56
32 INT325285 COMP Positive_regulation of UBR5 1 0.00 2.9 0 97.24
33 INT325587 Binding of Ang and Nppa 1 0.21 0.24 0 96.96
34 INT325594 Binding of Ang and Olfml3 1 0.01 0.1 0 96.96
35 INT325584 Binding of Olfml3 and Nppa 1 0.01 0.1 0 96.96
36 INT96801 Nxnl1 Negative_regulation of Mpo 1 0.01 0.62 0.13 96.92
37 INT325600 Nppa Positive_regulation of Pde2a 1 0.11 0.16 0.03 96.88
38 INT257343 Lox Regulation of Cyba 1 0.02 0.37 0.05 96.68
39 INT257338 Lox Regulation of Cybb 1 0.00 0.37 0.05 96.68
40 INT257339 Lox Regulation of Ncf1 1 0.02 0.37 0.05 96.68
41 INT325586 Nppa Positive_regulation of Prkg1 1 0.28 0.16 0.03 96.52
42 INT131355 Npr1 Regulation of Nppb 1 0.39 0.88 0.22 96.48
43 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73 96.16
44 INT273887 Binding of Jag1 and Notch2 1 0.02 1.06 0 96.16
45 INT131354 Npr1 Regulation of Nppa 1 0.40 0.88 0.22 95.84
46 INT238119 STAT3 Regulation of FANCC 1 0.02 0.17 0 95.76
47 INT308585 Binding of APOB and PLA2G7 1 0.07 0.69 0.09 95.72
48 INT230748 Agtr2 Positive_regulation of Gene_expression of Ros1 2 0.05 1.04 0.23 95.52
49 INT267998 Binding of XDH and Nos1 1 0.02 0.46 0.06 95.28
50 INT171162 Negative_regulation of Ace Negative_regulation of Gene_expression of Ccl2 1 0.02 1.18 0.1 95.24
51 INT172833 Binding of FFAR1 and T2dm2 1 0.00 1.55 0 95.08
52 INT177673 Avp Positive_regulation of Vmn1r51 1 0.04 0.53 0 95.04
53 INT350983 TP53 Regulation of VEGFA 1 0.03 0.61 0 95.04
54 INT350982 TSHB Regulation of VEGFA 1 0.01 0.64 0 95.04
55 INT350980 ESR1 Regulation of VEGFA 1 0.01 0.62 0 95.04
56 INT304884 Agtrap Positive_regulation of Gene_expression of Ros1 1 0.17 0.48 0.08 94.92
57 INT300304 Positive_regulation of Mapk14 Positive_regulation of Agt 1 0.14 1.5 0.08 94.64
58 INT184124 Socs3 Regulation of Il6 1 0.13 1.4 0.43 94.52
59 INT184128 Socs3 Negative_regulation of Il6 1 0.12 1.14 0.36 94.52
60 INT184119 Socs3 Negative_regulation of Csf3 1 0.21 0.64 0.08 94.52
61 INT332689 Binding of Edn1 and Ros1 1 0.08 0.71 0.14 94.44
62 INT238213 Positive_regulation of Bmx Positive_regulation of Phosphorylation of STAT3 1 0.12 0.16 0.03 94.04
63 INT306921 Ang Positive_regulation of Gene_expression of Ephx2 1 0.15 0.79 0.12 93.80
64 INT322258 Binding of Agtrap and l5H1 1 0.40 0.62 0.09 93.44
65 INT170817 CMA1 Positive_regulation of Gene_expression of AGT 1 0.19 1.41 0.14 92.88
66 INT317566 Car2 Positive_regulation of Camk2a 2 0.19 0.58 0.32 92.36
67 INT239339 Hdl1 Negative_regulation of Gene_expression of Paf 1 0.02 1.43 0.13 92.32
68 INT190825 Cl Regulation of Gopc 1 0.00 0.52 0.09 91.92
69 INT352496 AVP Regulation of Gene_expression of CRS 1 0.27 2.47 0.59 91.52
70 INT304885 Gene_expression of Ros1 Positive_regulation of Positive_regulation of Mapk1 1 0.14 0.52 0.06 91.44
71 INT300308 Positive_regulation of Mapk14 Positive_regulation of Trib3 1 0.03 1.42 0.07 91.36
72 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 90.96
73 INT135014 Binding of Ephb1 and Cabin1 1 0.09 0.32 0.3 90.80
74 INT239322 Hdl1 Positive_regulation of RCT 1 0.02 2.16 0.03 90.68
75 INT142332 Binding of SERPINH1 and TNNI3 1 0.03 1.05 0.17 90.64
76 INT88772 Negative_regulation of Binding of AGT and Agtrap 1 0.02 0.89 0.03 90.04
77 INT49058 Binding of IGHE and Positive_regulation of Localization of PTGDS 1 0.29 0.35 0.17 89.76
78 INT88773 Positive_regulation of Binding of AGT and Agtrap 1 0.01 0.88 0.05 89.64
79 INT88774 Binding of AGT and Agtrap 2 0.01 2.13 0.03 89.64
80 INT239402 Binding of NPPA and ASAP1 1 0.19 1.24 0.04 89.48
81 INT182499 Binding of AGTR1 and AGTR2 3 0.20 2.79 0.28 89.36
82 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43 89.24
83 INT273290 Binding of Atp2a2 and Tlx2 1 0.05 0.26 0 89.04
84 INT230723 ERVW-1 Positive_regulation of Gene_expression of EDN1 1 0.00 1.95 0 88.84
85 INT207681 Chrnb4 Positive_regulation of Scn2b 1 0.02 0.32 0.1 88.56
86 INT260601 Binding of ESR1 and Ppargc1a 1 0.01 0.48 0 88.44
87 INT300305 Mapk14 Positive_regulation of Gene_expression of Ctgf 1 0.19 1.25 0.17 88.40
88 INT273287 Binding of Atp2a2 and Pln 1 0.08 0.26 0 88.40
89 INT42073 Binding of PPBP and Tbxa2r 1 0.01 0.26 0.1 88.24
90 INT344721 Binding of AHA and Hdl1 1 0.02 1.16 0.15 87.92
91 INT354619 AR Positive_regulation of Gene_expression of Nppa 1 0.00 0.38 0 87.88
92 INT297208 Myoz1 Regulation of Dnm1l 1 0.05 0.17 0 87.40
93 INT297209 Myoz1 Regulation of Mef2a 1 0.04 0.09 0 87.40
94 INT297213 Myoz1 Regulation of Mef2c 1 0.02 0.09 0 87.40
95 INT239328 Hdl1 Regulation of Gene_expression of Kitl 1 0.08 1.86 0.2 86.72
96 INT254855 Agt Positive_regulation of Tgfb1 1 0.03 0.18 0.13 86.72
97 INT325606 Negative_regulation of Nppa Negative_regulation of Ang 1 0.25 0.46 0 86.64
98 INT210934 Gene_expression of Tlr4 Negative_regulation of Ccl2 1 0.47 0.69 0.54 86.56
99 INT126531 Adra1a Positive_regulation of Serpine1 1 0.03 0.31 0.34 86.48
100 INT354544 Avp Positive_regulation of ADCY1 1 0.24 2.23 0.22 86.44
101 INT207683 Chrnb4 Positive_regulation of Htr3b 1 0.26 0.31 0.1 86.40
102 INT290435 Positive_regulation of Binding of Mtor and Utp3 1 0.01 0.26 0 86.08
103 INT290436 Binding of Mtor and Utp3 1 0.00 0.26 0 86.08
104 INT327366 Binding of Fap and Ttr 1 0.33 2.9 0.28 85.84
105 INT325595 Nppa Negative_regulation of Ang 1 0.25 0.46 0 85.52
106 INT91097 Ptprg Positive_regulation of Npr1 1 0.00 0.62 0.08 85.44
107 INT207684 Chrnb4 Positive_regulation of Htr3a 1 0.22 0.3 0.1 85.20
108 INT193693 Binding of Myd88 and Pain1 1 0.14 0.82 0.13 85.12
109 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6 84.88
110 INT257870 Agt Positive_regulation of Akt1 2 0.18 1.5 0.09 84.88
111 INT239330 Positive_regulation of Ppara Positive_regulation of Hdl1 1 0.05 1.17 0.03 84.84
112 INT322236 Agt Regulation of Gene_expression of Slc6a4 1 0.42 0.63 0 84.72
113 INT322251 Slc6a4 Regulation of Gene_expression of Agtrap 1 0.43 0.63 0 84.72
114 INT322250 Ace Regulation of Gene_expression of Agt 1 0.43 0.63 0 84.72
115 INT322248 Slc6a4 Regulation of Gene_expression of Agt 1 0.42 0.63 0 84.72
116 INT322243 Agt Regulation of Gene_expression of Agtrap 1 0.50 0.63 0 84.72
117 INT322240 Ace Regulation of Gene_expression of Htr2a 1 0.13 0.63 0 84.72
118 INT322239 Ace Regulation of Gene_expression of Agtrap 1 0.44 0.63 0 84.72
119 INT322254 Agt Regulation of Gene_expression of Htr2a 1 0.15 0.63 0 84.72
120 INT322253 Agt Regulation of Gene_expression of Ace 1 0.43 0.63 0 84.72
121 INT322238 Slc6a4 Regulation of Gene_expression of Ace 1 0.37 0.63 0 84.72
122 INT322256 Ace Regulation of Gene_expression of Slc6a4 1 0.37 0.63 0 84.72
123 INT322247 Slc6a4 Regulation of Gene_expression of Htr2a 1 0.13 0.63 0 84.72
124 INT240131 Binding of Crp and Nppb 7 0.07 11.53 2.12 84.56
125 INT291837 Binding of Pecam1 and Vegfa 1 0.09 1.1 0.07 83.84
126 INT189396 MBD4 Regulation of C11orf2 1 0.05 0.66 0 83.76
127 INT239348 Binding of Apoa1 and Hdl1 1 0.03 3.34 0.05 83.44
128 INT304881 Ros1 Positive_regulation of Mapk1 1 0.25 0.36 0.1 83.28
129 INT239355 Binding of Nr1h2 and Positive_regulation of Gene_expression of CETP 1 0.17 3.75 0.14 83.16
130 INT239341 Binding of Abca1 and Hdl1 1 0.04 4.78 0 83.04
131 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58 83.04
132 INT265827 ACE Negative_regulation of ANGPT2 1 0.09 0.59 0.17 83.04
133 INT284139 EDNRB Positive_regulation of Gene_expression of EDNRA 1 0.12 0.45 0.22 83.04
134 INT283199 Binding of DMD and PTPRC 1 0.01 0.82 0 82.64
135 INT310674 Positive_regulation of Binding of ARSB and ELF3 1 0.07 2.46 0.05 82.52
136 INT113362 Gnat3 Positive_regulation of Serpina3c 1 0.17 0.25 0.09 82.48
137 INT239323 Binding of Nr1h2 and Positive_regulation of Positive_regulation of Tgfb1 1 0.00 3.71 0.14 82.28
138 INT113363 Napa Positive_regulation of Serpina3c 1 0.15 0.25 0.09 82.08
139 INT238215 Binding of STAT3 and Bmx 1 0.12 0.63 0.08 82.00
140 INT239345 Apoa1 Positive_regulation of RCT 1 0.02 1.15 0.03 81.88
141 INT310675 Binding of ARSB and ELF3 1 0.06 2.4 0.05 81.84
142 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58 81.64
143 INT269502 Lta Negative_regulation of Map2k1 1 0.17 0.48 0.03 81.64
144 INT269504 Lta Negative_regulation of Map2k1 Negative_regulation of Nos1 1 0.17 0.49 0.03 81.64
145 INT239338 Arg2 Positive_regulation of RCT 1 0.01 1.15 0.03 81.44
146 INT260600 Binding of Ppargc1a and Siglec1 1 0.14 1.25 0 81.32
147 INT36328 Binding of AMPD1 and Hmgcl 1 0.01 1.02 0 81.12
148 INT114077 Gtf3a Positive_regulation of Tfam 1 0.09 1.08 0.09 81.04
149 INT300306 Agt Positive_regulation of Mapk14 1 0.14 1.51 0.11 81.04
150 INT207682 Chrnb4 Positive_regulation of Hcn4 1 0.35 0.29 0.1 80.96
151 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24 80.92
152 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58 80.60
153 INT239318 Binding of Cor and Hdl1 1 0.07 1.69 0.05 80.44
154 INT277987 Regulation of Csf3 Positive_regulation of Epc1 1 0.00 0.51 0.11 80.28
155 INT285979 Ros1 Positive_regulation of Trib3 2 0.02 2.18 0.2 80.24
156 INT332687 Ros1 Positive_regulation of Crk 1 0.17 0.77 0.12 80.24
157 INT277988 Csf3 Positive_regulation of Epc1 1 0.00 0.51 0.11 79.80
158 INT305271 Binding of Lep and Obsty1 1 0.06 4.86 0 79.64
159 INT332685 Trib3 Positive_regulation of Binding of Ros1 1 0.01 0.74 0.12 79.56
160 INT322237 Binding of Agtrap and Hcm 1 0.14 2.3 0.19 79.16
161 INT322255 Mir155 Regulation of Agtrap 1 0.21 0.33 0 78.48
162 INT325284 Binding of COMP and MCL1 1 0.01 1.69 0 78.12
163 INT256210 NPPB Regulation of PVR 1 0.24 1.14 0 77.60
164 INT256211 NPPB Regulation of PDAP1 1 0.28 1.14 0 77.60
165 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4 77.36
166 INT275159 Agt Positive_regulation of Phosphorylation of Stat3 1 0.04 1.44 0.2 77.36
167 INT356377 Dmd Positive_regulation of Negative_regulation of Mib2 1 0.03 0.51 0 77.32
168 INT267217 Gene_expression of Hspb8 Negative_regulation of Positive_regulation of Casp3 1 0.14 2.8 0.04 76.96
169 INT350020 ARID1B Regulation of Positive_regulation of Tnf 1 0.04 1.78 0.16 76.96
170 INT350013 ARID1B Regulation of Positive_regulation of NFKB1 1 0.00 1.77 0.16 76.96
171 INT300313 TGFB1 Positive_regulation of Mapk14 1 0.01 1.5 0.11 76.72
172 INT126551 Agt Positive_regulation of Gene_expression of Ptgs1 1 0.25 0.92 0.24 76.48
173 INT126552 Agt Positive_regulation of Gene_expression of Ptgs2 1 0.32 0.92 0.24 76.48
174 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4 75.84
175 INT325598 Ang Positive_regulation of Camk2a 1 0.21 0.29 0 75.76
176 INT325601 Ang Positive_regulation of Phosphorylation of Camk2a 1 0.21 0.29 0 75.76
177 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61 75.20
178 INT317396 Binding of Car2 and Prkag1 1 0.07 0.31 0 75.12
179 INT91098 Gcgr Positive_regulation of Npr1 1 0.01 0.38 0.06 75.00
180 INT126549 Agt Positive_regulation of Ptgs2 1 0.32 0.9 0.23 75.00
181 INT91095 Naf1 Positive_regulation of Npr1 1 0.01 0.18 0 75.00
182 INT91096 Naf1 Positive_regulation of Binding of Npr1 1 0.02 0.19 0 75.00
183 INT79523 Binding of HSD11B1 and C9orf3 1 0.52 1.12 0.06 75.00
184 INT336892 Positive_regulation of Epc2 Positive_regulation of Localization of Spp1 1 0.00 0.62 0.19 74.96
185 INT336890 Positive_regulation of Epc2 Positive_regulation of Spp1 1 0.00 0.62 0.19 74.96
186 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6 73.84
187 INT325602 Binding of Ang and Pde2a 1 0.07 0.15 0 73.72
188 INT242995 Agt Positive_regulation of Spp1 1 0.36 1.82 0.33 72.92
189 INT265826 Binding of ACE and SERPINE1 1 0.24 1.08 0.3 72.88
190 INT250024 Positive_regulation of Ros1 Positive_regulation of Gtf3a 1 0.00 1.26 0.08 72.60
191 INT250023 Positive_regulation of Ros1 Positive_regulation of Nfkb1 1 0.04 1.26 0.08 72.60
192 INT187290 Binding of HEY1 and Gtf3a 1 0.00 6.18 0.83 72.56
193 INT344714 Nr1h4 Negative_regulation of Gene_expression of Lipg 1 0.02 0.77 0.23 72.00
194 INT317393 Binding of Car2 and Ide 1 0.03 0.3 0 71.84
195 INT49057 Positive_regulation of CEL Positive_regulation of Localization of LTC4S 1 0.41 0.28 0.18 71.60
196 INT242996 Adipoq Negative_regulation of Transcription of Cd68 1 0.22 0.6 0.21 71.40
197 INT242994 Adipoq Negative_regulation of Spp1 1 0.19 0.59 0.21 71.40
198 INT213005 Hdl1 Positive_regulation of Akt1 3 0.19 3.81 0.14 71.36
199 INT275171 Binding of Stat3 and Rac1 Positive_regulation of Rac1 Positive_regulation of Stat3 1 0.01 0.73 0.1 70.20
200 INT275158 Rac1 Positive_regulation of Stat3 1 0.07 0.72 0.1 70.20

Single Events

The table below shows the top 200 pain related interactions that have been reported for Coronary Heart Disease. They are ordered first by their pain relevance and then by number of times they were reported in Coronary Heart Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 100.00
2 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05 100.00
3 INT116848 Negative_regulation of Chdh 10 0.42 19.68 1.95 100.00
4 INT17686 Negative_regulation of Hdl1 72 0.36 81.85 7.74 100.00
5 INT207451 Binding of PLA2G7 3 0.48 11.12 1.32 100.00
6 INT178889 Negative_regulation of CHDH 38 0.48 36.69 1.53 100.00
7 INT1631 Binding of Hdl1 42 0.36 49.22 2.92 100.00
8 INT267196 Gene_expression of Cryab 17 0.64 22.5 0.38 100.00
9 INT58477 Gene_expression of Chdh 33 0.74 39.48 19.78 100.00
10 INT86437 Binding of IL6 154 0.48 121.22 29.3 100.00
11 INT178888 Gene_expression of CHDH 41 0.65 38.66 2.51 100.00
12 INT22909 Positive_regulation of Chdh 26 0.68 28.69 16.13 100.00
13 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37 100.00
14 INT120752 Positive_regulation of Gene_expression of NPPB 17 0.67 16.4 2.21 100.00
15 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59 100.00
16 INT84978 Positive_regulation of CHDH 21 0.50 21.97 0.48 100.00
17 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 100.00
18 INT99069 Positive_regulation of Gene_expression of Mapk14 42 0.53 29.84 23.16 100.00
19 INT312270 Positive_regulation of Xcl1 4 0.31 3.32 0.44 100.00
20 INT84979 Regulation of CHDH 22 0.38 22.34 0.78 100.00
21 INT197681 Binding of CHDH 40 0.48 33.72 2.13 100.00
22 INT193623 Transcription of ARVD4 1 0.58 1.63 0 100.00
23 INT14685 Regulation of Orm1 1 0.40 0.66 0.31 100.00
24 INT344687 Negative_regulation of Gene_expression of Chdh 1 0.04 1.73 0 100.00
25 INT7523 Regulation of ADRA1D 42 0.45 11.63 14.52 100.00
26 INT171747 Gene_expression of ACD 4 0.57 4.44 0.68 100.00
27 INT318169 Regulation of Xcl1 1 0.15 1.14 0.19 100.00
28 INT193624 Binding of ARVD4 1 0.31 1.14 0.08 100.00
29 INT229749 Regulation of Gene_expression of CHDH 7 0.27 5.94 0.12 100.00
30 INT267187 Negative_regulation of Grem1 2 0.19 2.16 0.04 100.00
31 INT65489 Regulation of Gene_expression of Crp 28 0.59 29.17 7.56 100.00
32 INT14904 Gene_expression of CAMK2N2 1 0.00 0.56 0.18 100.00
33 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18 100.00
34 INT88134 Negative_regulation of Gene_expression of Spp1 2 0.41 1.94 0.32 100.00
35 INT44028 Positive_regulation of Grem1 4 0.68 3.64 0.5 100.00
36 INT66646 Regulation of Chdh 13 0.44 16.24 8.84 100.00
37 INT308586 Negative_regulation of Binding of PLA2G7 1 0.43 0.69 0.1 100.00
38 INT5762 Negative_regulation of Gene_expression of Agt 18 0.57 6.09 5.84 100.00
39 INT71601 Positive_regulation of ACD 11 0.60 6.55 0.9 100.00
40 INT178890 Localization of CHDH 12 0.62 15.76 1.49 100.00
41 INT130300 Gene_expression of Abcc3 14 0.70 5.34 4.96 100.00
42 INT147159 Regulation of Gene_expression of Abcc3 4 0.55 2.96 2.97 100.00
43 INT180035 Positive_regulation of Gene_expression of Chdh 2 0.22 8.21 5.78 100.00
44 INT344694 Positive_regulation of Binding of Niacr1 1 0.28 1.91 0 100.00
45 INT17574 Binding of CISH 23 0.31 4.3 0.93 100.00
46 INT75975 Gene_expression of Grem1 3 0.59 2.22 0.18 100.00
47 INT344693 Positive_regulation of Negative_regulation of Chdh 1 0.05 1.76 0 100.00
48 INT344683 Positive_regulation of Negative_regulation of Niacr1 1 0.28 1.77 0 100.00
49 INT84826 Negative_regulation of ACD 6 0.50 4.02 0.55 100.00
50 INT28060 Positive_regulation of Hdlcl1 48 0.66 37.31 3.79 100.00
51 INT229350 Positive_regulation of Negative_regulation of Hdlcl1 2 0.29 1.9 0 100.00
52 INT142802 Binding of Ldlr 8 0.47 5.08 0.65 100.00
53 INT45342 Binding of AVSD1 6 0.31 7.23 0.27 100.00
54 INT210069 Regulation of Gene_expression of SH3GL3 1 0.03 0.45 0.04 100.00
55 INT170922 Binding of Ppara 59 0.45 28.45 6.7 99.98
56 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 99.98
57 INT212966 Negative_regulation of Gene_expression of Hdl1 8 0.27 10.98 0.49 99.98
58 INT24332 Regulation of Hdl1 28 0.45 45.45 4.26 99.96
59 INT199173 Gene_expression of Aldh2 25 0.77 14.1 2.12 99.96
60 INT330414 Positive_regulation of Gene_expression of Aldh2 11 0.69 8.58 1.09 99.96
61 INT20348 Negative_regulation of Tbxa2r 47 0.59 19.88 7.68 99.96
62 INT4781 Gene_expression of TH 68 0.73 26.92 24.01 99.96
63 INT226178 Gene_expression of thd 14 0.23 8.29 2.92 99.96
64 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73 99.96
65 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64 99.96
66 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81 99.92
67 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 99.92
68 INT812 Localization of INS 1026 0.81 515.6 145.31 99.92
69 INT14572 Binding of INS 205 0.48 175.43 13.38 99.92
70 INT61116 Positive_regulation of Ppara 119 0.69 58.62 21.6 99.92
71 INT28699 Binding of F7 9 0.35 3.47 0.67 99.92
72 INT28701 Gene_expression of F7 1 0.55 1.51 0.12 99.92
73 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 99.92
74 INT40164 Binding of Por 2 0.37 0.5 0.51 99.92
75 INT18340 Gene_expression of CRX 16 0.22 13.85 7.13 99.92
76 INT41008 Binding of Ubd 1 0.31 0.66 0.17 99.90
77 INT77670 Positive_regulation of ACLY 24 0.49 21.68 3.12 99.88
78 INT64899 Binding of NAAA 4 0.33 2.82 0.85 99.88
79 INT294370 Negative_regulation of Niacr1 3 0.24 2.54 0.42 99.86
80 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 99.86
81 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 99.84
82 INT9084 Positive_regulation of Nppb 74 0.70 69.77 11.85 99.84
83 INT56447 Positive_regulation of Icam1 64 0.64 64.14 16.16 99.84
84 INT139678 Positive_regulation of Hspb8 23 0.68 23.94 1.85 99.84
85 INT239303 Positive_regulation of Gene_expression of Hdl1 8 0.36 12.46 0.53 99.84
86 INT58288 Positive_regulation of Gene_expression of Crp 83 0.61 82.23 23.7 99.84
87 INT6115 Positive_regulation of Pigm 82 0.64 16.96 25.73 99.84
88 INT172452 Gene_expression of Myc 121 0.78 69.56 1.36 99.84
89 INT248543 Positive_regulation of Mef2c 7 0.69 2.82 0.18 99.84
90 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 99.82
91 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 99.82
92 INT99104 Gene_expression of Npr1 5 0.78 3.31 2.8 99.82
93 INT9819 Gene_expression of nt 15 0.55 5.09 6.25 99.82
94 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.80
95 INT181829 Binding of Ppargc1a 16 0.48 9.61 0.34 99.80
96 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 99.80
97 INT47021 Positive_regulation of Positive_regulation of DBP 2 0.19 1.06 0.69 99.80
98 INT385 Gene_expression of Agt 182 0.78 63.62 37.91 99.78
99 INT31582 Gene_expression of Hdl1 103 0.66 118.95 6.42 99.76
100 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.76
101 INT138104 Binding of Lta 2 0.39 2.63 0.72 99.76
102 INT57424 Positive_regulation of TNNT1 42 0.67 31.84 9.7 99.76
103 INT18025 Binding of Pah 32 0.45 30.72 7.93 99.76
104 INT129105 Gene_expression of Mstn 95 0.76 29.96 0.32 99.76
105 INT78995 Negative_regulation of Agtr2 26 0.42 13.05 4.56 99.76
106 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53 99.76
107 INT1180 Gene_expression of Ren 63 0.77 27.33 10.51 99.76
108 INT1178 Positive_regulation of Gene_expression of Ren 16 0.60 7.71 2.41 99.76
109 INT9110 Binding of PAH 32 0.41 42.1 3.1 99.76
110 INT114993 Binding of Myo5a 15 0.30 11.46 5.48 99.76
111 INT3854 Binding of SCD 16 0.41 11.14 3.7 99.76
112 INT213217 Negative_regulation of Binding of PAH 2 0.32 2.03 0.19 99.76
113 INT73939 Negative_regulation of Cd36 7 0.57 6.3 0.95 99.74
114 INT39468 Positive_regulation of hf 10 0.33 13.5 1.32 99.74
115 INT229626 Negative_regulation of Localization of ACE 3 0.41 2 0.36 99.74
116 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92 99.72
117 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 99.72
118 INT15851 Positive_regulation of Trpv3 11 0.60 4.6 4.35 99.72
119 INT25834 Positive_regulation of Dbp 59 0.68 24.34 9.32 99.70
120 INT141494 Positive_regulation of ZIC3 1 0.36 1.31 0.16 99.68
121 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95 99.68
122 INT11042 Localization of Tbxa2r 26 0.76 10.15 7.24 99.68
123 INT101243 Regulation of STAT3 12 0.62 9.98 1.92 99.68
124 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 99.64
125 INT47766 Transcription of Fos 25 0.69 8.78 4.42 99.64
126 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 99.64
127 INT8989 Binding of Npr1 25 0.36 5.52 14.58 99.64
128 INT207448 Negative_regulation of PLA2G7 5 0.47 5.65 1.08 99.64
129 INT62545 Regulation of Gene_expression of Icam1 17 0.49 14.26 4.06 99.64
130 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04 99.64
131 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 99.64
132 INT115783 Positive_regulation of Gene_expression of GNAQ 2 0.49 0.79 0.7 99.64
133 INT115784 Gene_expression of GNAQ 5 0.65 4.48 0.7 99.64
134 INT142464 Gene_expression of Socs3 58 0.77 52.04 15.34 99.64
135 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 99.64
136 INT2774 Binding of Crp 241 0.48 195.89 44.39 99.62
137 INT137614 Gene_expression of Lgals3 70 0.77 66.13 12.53 99.62
138 INT252209 Positive_regulation of Gene_expression of Lgals3 10 0.57 8.29 1.62 99.62
139 INT107898 Gene_expression of Trpv2 27 0.76 10.55 9.28 99.60
140 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 99.60
141 INT136287 Regulation of Positive_regulation of Icam1 1 0.39 1.32 0.24 99.60
142 INT107895 Positive_regulation of Gene_expression of Trpv2 4 0.46 0.98 1.6 99.60
143 INT44717 Gene_expression of TNFSF14 12 0.75 13.44 3.72 99.60
144 INT21609 Positive_regulation of RASGRP1 58 0.50 40.78 5.47 99.58
145 INT74545 Negative_regulation of Gene_expression of Prkcg 22 0.42 7.77 16.26 99.58
146 INT7475 Positive_regulation of Hdl1 138 0.67 175.81 15.05 99.56
147 INT27670 Negative_regulation of Ace 122 0.57 79.21 18.08 99.56
148 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 99.56
149 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 99.56
150 INT797 Regulation of Penk 812 0.62 111.13 542.24 99.56
151 INT67379 Positive_regulation of Cd34 38 0.58 26.18 3.28 99.56
152 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 99.56
153 INT2991 Regulation of PIK3C2A 6 0.60 4.46 0.99 99.56
154 INT17381 Gene_expression of Tbxa2r 146 0.78 65.01 34.15 99.54
155 INT88130 Gene_expression of Spp1 13 0.74 12.96 3.07 99.54
156 INT225673 Positive_regulation of Gamt 1 0.42 0.67 0.03 99.54
157 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.52
158 INT62950 Gene_expression of NPPB 73 0.75 65.91 6.54 99.52
159 INT216932 Positive_regulation of Negative_regulation of Il6 3 0.38 4.88 1.55 99.52
160 INT123731 Positive_regulation of Agtrap 12 0.50 7.91 1 99.52
161 INT148074 Regulation of Agt 9 0.49 5.42 0.7 99.52
162 INT157906 Binding of TRPC1 2 0.32 0.91 0.26 99.52
163 INT144946 Localization of Icam1 21 0.75 21.84 5.33 99.48
164 INT17056 Gene_expression of DLD 37 0.57 13.15 5.47 99.48
165 INT90943 Negative_regulation of P2rx1 13 0.42 8.21 7.22 99.48
166 INT99426 Negative_regulation of Gene_expression of Atp2a2 19 0.59 13.7 1.96 99.48
167 INT46320 Negative_regulation of Ttr 4 0.15 2.54 1 99.48
168 INT323416 Localization of NKX2-5 1 0.65 1.75 0.1 99.48
169 INT315494 Protein_catabolism of Ctnnbl1 1 0.52 0.39 0 99.48
170 INT291820 Regulation of Gene_expression of Txn2 1 0.04 1.67 0.06 99.46
171 INT29975 Regulation of Mlvi3 1 0.01 0.62 0 99.46
172 INT29976 Regulation of Mlvi2 1 0.00 0.62 0 99.46
173 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 99.44
174 INT17425 Regulation of Gene_expression of Ins1 23 0.45 18.99 5.61 99.44
175 INT239841 Regulation of Protein_catabolism of TNNI3 1 0.32 1.6 0.2 99.40
176 INT161376 Protein_catabolism of TNNI3 7 1.00 3.92 0.67 99.40
177 INT3605 Negative_regulation of OPA1 14 0.38 10.88 2.84 99.40
178 INT110040 Binding of Nppb 9 0.18 8.91 0.19 99.40
179 INT61117 Gene_expression of Ppara 158 0.68 69.3 15.98 99.38
180 INT67424 Positive_regulation of Gene_expression of Selp 36 0.68 17.08 7.95 99.38
181 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 99.38
182 INT110523 Binding of TRPC6 2 0.47 0.91 0.33 99.38
183 INT110201 Positive_regulation of Sbp 10 0.49 5.25 1.55 99.38
184 INT56445 Regulation of Icam1 14 0.39 15.4 5.32 99.36
185 INT52113 Gene_expression of CETP 25 0.69 25.71 0.99 99.36
186 INT116724 Positive_regulation of Gene_expression of CETP 3 0.41 7.92 0.23 99.36
187 INT27106 Positive_regulation of nt 6 0.50 4.41 1.97 99.36
188 INT16923 Positive_regulation of Tnni3 32 0.50 25.01 5.44 99.36
189 INT3366 Localization of PLEK 44 0.78 15.83 9.55 99.36
190 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2 99.34
191 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 99.34
192 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52 99.34
193 INT70886 Positive_regulation of Gene_expression of Pdgfb 13 0.45 12.57 1.17 99.34
194 INT70893 Positive_regulation of Gene_expression of IGF2 5 0.67 6.13 0.44 99.34
195 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 99.34
196 INT13354 Transcription of TNF 108 0.72 85.81 42.32 99.34
197 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58 99.34
198 INT42038 Localization of ACE 26 0.80 8.88 7.06 99.34
199 INT157932 Positive_regulation of ADHD1 46 0.48 52.18 6.13 99.34
200 INT198049 Positive_regulation of JAK2 16 0.58 5.35 0.96 99.32
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