D:Craniofacial Abnormalities

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Abnormalities Craniofacial, Abnormality Craniofacial, Craniofacial Abnormality
Documents 30
Hot Single Events 20
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Craniofacial Abnormalities. They are ordered first by their relevance to Craniofacial Abnormalities and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT335887 Akt1 Regulation of Lrp6 1 0.06 0.15 0 46.96
2 INT335884 Akt1 Regulation of Positive_regulation of Wnt5a 1 0.03 0.15 0 45.76
3 INT335883 Binding of Lrp6 and Wnt5a 1 0.27 0.08 0 30.00
4 INT335888 Lrp5 Negative_regulation of Gene_expression of Tph1 1 0.22 0.15 0.21 5.00
5 INT335890 Binding of Dkk1 and Lrp4 1 0.37 0.64 0.07 5.00
6 INT335886 Binding of Sost and Lrp4 1 0.28 0.65 0.07 5.00
7 INT279889 Il6 Regulation of Socs3 1 0.21 0.17 0.05 5.00
8 INT254433 Binding of Lrp5 and Sost 2 0.39 1.51 0.03 5.00
9 INT279885 Ctcf Regulation of H19 1 0.12 0 0 5.00
10 INT279891 Shbdp1 Negative_regulation of PCDHB@ 1 0.01 0.09 0 5.00
11 INT308927 Gtf2i Positive_regulation of Gene_expression of Parp1 1 0.24 0 0 5.00
12 INT279886 Shbdp1 Negative_regulation of Pcdhb1 1 0.10 0.09 0 5.00
13 INT279884 Nipbl Regulation of Transcription of Pcdhb1 1 0.25 0.05 0 5.00
14 INT279892 Shbdp1 Negative_regulation of Gene_expression of PCDHB@ 1 0.01 0.09 0 5.00
15 INT335891 Binding of Dkk1 and Lrp5 1 0.39 0.57 0 5.00
16 INT335882 Dkk1 Negative_regulation of Wnt2 1 0.02 0.15 0 5.00
17 INT279888 Binding of Rec8 and Nipbl 1 0.01 0.81 0 5.00
18 INT279890 Nipbl Regulation of Gene_expression of PCDHB@ 1 0.07 0.1 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Craniofacial Abnormalities. They are ordered first by their pain relevance and then by number of times they were reported in Craniofacial Abnormalities. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT228870 Negative_regulation of Lpar1 17 0.51 20.97 8.77 97.02
2 INT111739 Negative_regulation of Npy 15 0.43 4.9 4.65 97.02
3 INT95561 Negative_regulation of Vldlr 9 0.53 2.59 0.84 97.02
4 INT279847 Negative_regulation of Cebpb 2 0.28 1.82 0.44 97.02
5 INT279843 Negative_regulation of Ebf1 1 0.37 0.6 0 97.02
6 INT308912 Positive_regulation of Gtf2ird1 1 0.46 1.43 0 94.40
7 INT297757 Transcription of Lrp5 2 0.68 0.82 0 92.80
8 INT297820 Regulation of Transcription of Lrp5 2 0.44 0.83 0 92.80
9 INT335866 Regulation of Transcription of Lrp6 1 0.42 0.25 0 92.80
10 INT335873 Transcription of Lrp6 1 0.64 0.25 0 92.80
11 INT179654 Positive_regulation of Eln 5 0.44 4.3 0.43 91.16
12 INT308913 Positive_regulation of Clip2 1 0.42 0.77 0 91.16
13 INT308905 Gene_expression of Gtf2i 1 0.65 1.73 0.25 90.04
14 INT308914 Binding of Gtf2i 1 0.47 0.99 0.08 90.04
15 INT308907 Negative_regulation of Gtf2i 1 0.31 1.22 0.16 87.12
16 INT213503 Regulation of Wnt2 9 0.37 3.54 0.56 86.04
17 INT308916 Gene_expression of Clip2 1 0.50 1.14 0 82.72
18 INT35349 Gene_expression of CENPJ 52 0.57 25.36 2.54 82.24
19 INT335875 Regulation of Lrp6 1 0.57 0.43 0.27 82.20
20 INT297804 Regulation of Lrp5 6 0.60 2.31 0.27 82.20
21 INT244771 Gene_expression of Satb2 4 0.68 1.27 0.03 76.60
22 INT143838 Gene_expression of Pitx2 3 0.53 1.86 0.09 76.32
23 INT279850 Gene_expression of Trps1 1 0.38 0.47 0 76.04
24 INT279858 Gene_expression of Tcof1 1 0.40 0.47 0 75.76
25 INT279869 Negative_regulation of Nipbl 1 0.43 4.3 0.03 75.68
26 INT105344 Gene_expression of Cited2 5 0.78 3.65 0.76 75.48
27 INT279846 Gene_expression of Nipbl 1 0.68 11.1 0.56 75.12
28 INT59555 Binding of RYR1 39 0.42 8.65 4.92 67.16
29 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22 62.08
30 INT335870 Regulation of Gene_expression of Tnfrsf11b 1 0.13 0.11 0 58.52
31 INT123459 Gene_expression of Tnfrsf11b 35 0.58 24.16 7.26 57.96
32 INT254426 Gene_expression of Lrp5 5 0.67 3.28 0.06 54.84
33 INT19483 Positive_regulation of Ppcs 3 0.37 14.1 1.36 54.80
34 INT27813 Regulation of CENPJ 12 0.29 14.26 0.99 52.60
35 INT162576 Positive_regulation of Wnt5a 3 0.48 0.71 0.08 42.40
36 INT335872 Positive_regulation of Gene_expression of Lrp6 1 0.46 0.18 0 41.36
37 INT335881 Gene_expression of Lrp6 1 0.62 0.09 0 39.92
38 INT254427 Binding of Lrp5 10 0.48 5.43 0.26 38.72
39 INT188047 Positive_regulation of Wnt2 51 0.58 31.41 2.94 36.48
40 INT201777 Phosphorylation of Wnt2 2 0.03 1.31 0.05 36.48
41 INT335865 Positive_regulation of Phosphorylation of Lrp6 1 0.64 0.46 0.05 35.60
42 INT335862 Phosphorylation of Lrp6 1 0.76 0.37 0.05 34.48
43 INT279856 Regulation of Pcdhb1 1 0.42 0.89 0 25.00
44 INT279841 Transcription of Nipbl 1 0.63 1.21 0 25.00
45 INT279882 Regulation of PCDHB@ 1 0.06 0.89 0 25.00
46 INT279871 Negative_regulation of Transcription of Nipbl 1 0.43 1.22 0 25.00
47 INT279830 Regulation of Transcription of Nipbl 1 0.39 0.62 0 25.00
48 INT279842 Regulation of Rec8 1 0.01 0.6 0 25.00
49 INT335880 Regulation of Wnt5a 1 0.32 0.07 0 22.24
50 INT279864 Regulation of Ctcf 1 0.14 0.18 0 21.04
51 INT254429 Negative_regulation of Lrp5 4 0.57 1.95 0.18 12.64
52 INT2659 Positive_regulation of Psgb1 2 0.40 3.25 0.3 9.64
53 INT263329 Localization of CNBP 1 0.01 1.59 0 5.36
54 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
55 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
56 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
57 INT86521 Gene_expression of Lpar1 167 0.78 154.61 80.35 5.00
58 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
59 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
60 INT154007 Gene_expression of da 46 0.56 15.28 28.22 5.00
61 INT111081 Gene_expression of CA1 19 0.75 51.09 26.64 5.00
62 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 5.00
63 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51 5.00
64 INT129883 Gene_expression of Dkk1 56 0.77 45.42 12.52 5.00
65 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28 5.00
66 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 5.00
67 INT102572 Gene_expression of Ccnd1 79 0.69 56.37 7.34 5.00
68 INT67635 Negative_regulation of Gnas 29 0.04 11.4 6.32 5.00
69 INT84572 Gene_expression of Zmat3 67 0.07 37.61 5.86 5.00
70 INT233 Binding of Gast 31 0.42 17.07 5.21 5.00
71 INT78393 Gene_expression of Adm 16 0.78 8.4 4.92 5.00
72 INT91463 Positive_regulation of NFKB2 19 0.40 17.7 4.6 5.00
73 INT111156 Negative_regulation of Dkk1 21 0.58 20.08 4.27 5.00
74 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21 5.00
75 INT168418 Positive_regulation of RCT 32 0.55 20.2 4.07 5.00
76 INT126659 Gene_expression of Tph1 22 0.78 2.04 4.04 5.00
77 INT94303 Gene_expression of Upf1 44 0.04 11.62 3.87 5.00
78 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68 5.00
79 INT123815 Gene_expression of Parp1 42 0.67 27.82 3.02 5.00
80 INT161840 Gene_expression of Tnfrsf11b 17 0.78 12.44 2.63 5.00
81 INT96693 Binding of COL2A1 45 0.46 37.11 2.61 5.00
82 INT61784 Positive_regulation of CENPJ 27 0.51 11.46 2.28 5.00
83 INT198885 Gene_expression of Lrp1 33 0.57 10.2 1.91 5.00
84 INT112867 Positive_regulation of Gene_expression of Ccnd1 15 0.56 13.22 1.77 5.00
85 INT92311 Regulation of SIL1 7 0.44 6.2 1.61 5.00
86 INT59837 Regulation of Upf1 5 0.03 1.37 1.45 5.00
87 INT103907 Negative_regulation of Upf1 15 0.37 4.3 1.4 5.00
88 INT242153 Negative_regulation of Wnt2 19 0.49 11.87 1.37 5.00
89 INT22871 Gene_expression of ELN 30 0.68 14.86 1.33 5.00
90 INT108519 Binding of Lrp6 8 0.44 1.47 1.19 5.00
91 INT208536 Positive_regulation of Positive_regulation of Gsk3b 6 0.30 4.83 1.11 5.00
92 INT308910 Gene_expression of Gtf2ird1 2 0.78 2.21 1.09 5.00
93 INT160576 Gene_expression of Psgb1 3 0.35 1.63 1.08 5.00
94 INT135039 Gene_expression of Cd1 11 0.60 5.66 1.05 5.00
95 INT165338 Binding of Dkk1 4 0.37 3.64 1.04 5.00
96 INT116797 Gene_expression of Osmr 9 0.73 1.12 1 5.00
97 INT124374 Binding of Wnt2 21 0.31 10.16 0.99 5.00
98 INT118254 Negative_regulation of Ppcs 4 0.39 2.49 0.79 5.00
99 INT335876 Negative_regulation of Sost 11 0.51 6.77 0.67 5.00
100 INT242137 Negative_regulation of Positive_regulation of Gsk3b 7 0.39 2.99 0.67 5.00
101 INT182010 Regulation of Tnfrsf11b 2 0.18 1.13 0.67 5.00
102 INT245721 Localization of FRZB 6 0.78 4.3 0.6 5.00
103 INT225355 Gene_expression of Set 15 0.37 2.98 0.47 5.00
104 INT201524 Localization of Wnt2 14 0.62 9.24 0.46 5.00
105 INT80624 Regulation of CNBP 5 0.36 3.36 0.45 5.00
106 INT238058 Negative_regulation of Shbdp1 4 0.10 1.36 0.42 5.00
107 INT263327 Positive_regulation of Positive_regulation of NFKB2 2 0.08 2.95 0.42 5.00
108 INT52297 Gene_expression of Ucma 2 0.65 1.3 0.41 5.00
109 INT277463 Localization of Sfrp1 2 0.23 0.64 0.36 5.00
110 INT101902 Negative_regulation of Mki67 12 0.39 7.92 0.34 5.00
111 INT308908 Negative_regulation of Gene_expression of Loca1 1 0.14 0.81 0.34 5.00
112 INT308906 Gene_expression of Loca1 1 0.23 0.8 0.33 5.00
113 INT328080 Localization of Ppcs 1 0.40 1.23 0.31 5.00
114 INT308909 Negative_regulation of Gtf2ird1 4 0.54 2.13 0.29 5.00
115 INT335874 Regulation of Lrp4 1 0.18 0 0.23 5.00
116 INT177643 Binding of CENPJ 12 0.36 8.59 0.22 5.00
117 INT335878 Localization of Sost 3 0.69 1.11 0.22 5.00
118 INT312604 Gene_expression of Lrp4 2 0.71 1.48 0.21 5.00
119 INT335879 Negative_regulation of Gene_expression of Tph1 1 0.19 0.15 0.21 5.00
120 INT335864 Gene_expression of Sost 4 0.77 2.36 0.2 5.00
121 INT181059 Gene_expression of Rnase1 5 0.25 0.98 0.19 5.00
122 INT279853 Negative_regulation of Gene_expression of Nipbl 1 0.51 2.37 0.19 5.00
123 INT335869 Binding of Sost 6 0.32 1.79 0.18 5.00
124 INT328079 Positive_regulation of Positive_regulation of Ppcs 1 0.27 1.35 0.17 5.00
125 INT308918 Negative_regulation of Loca1 1 0.14 0.4 0.17 5.00
126 INT335861 Localization of Lrp6 1 0.69 0.54 0.17 5.00
127 INT108463 Binding of Ppcs 6 0.37 3.16 0.15 5.00
128 INT238021 Negative_regulation of NNT 1 0.04 0.39 0.13 5.00
129 INT128990 Binding of Cd1 2 0.31 1.32 0.11 5.00
130 INT254428 Binding of Lrp4 4 0.44 1.52 0.11 5.00
131 INT350956 Binding of Psgb1 1 0.03 1.64 0.08 5.00
132 INT350958 Positive_regulation of PSG9 1 0.07 1.56 0.07 5.00
133 INT279840 Positive_regulation of Gene_expression of Nipbl 1 0.44 0.22 0.07 5.00
134 INT335871 Negative_regulation of Sfrp2 1 0.18 0.91 0.06 5.00
135 INT335860 Negative_regulation of Sfrp1 1 0.18 0.91 0.06 5.00
136 INT263328 Positive_regulation of KIF20B 1 0.28 2.56 0.04 5.00
137 INT335868 Negative_regulation of Gene_expression of Sost 2 0.58 1.12 0.04 5.00
138 INT279862 Binding of Nipbl 1 0.36 1.22 0.04 5.00
139 INT279851 Positive_regulation of Nipbl 1 0.44 0.19 0.04 5.00
140 INT335867 Positive_regulation of Negative_regulation of Sfrp2 1 0.14 0.49 0.03 5.00
141 INT328081 Phosphorylation of Ppcs 1 0.44 0.76 0.03 5.00
142 INT279854 Gene_expression of Ptx3 1 0.48 0.17 0.03 5.00
143 INT335859 Regulation of Sfrp1 1 0.08 0.43 0.03 5.00
144 INT279866 Regulation of Stag1 1 0.38 0.09 0 5.00
145 INT279868 Positive_regulation of Positive_regulation of Pcdhb1 1 0.47 0.08 0 5.00
146 INT279831 Positive_regulation of Lias 1 0.01 0.26 0 5.00
147 INT279834 Negative_regulation of Pcdhb7 1 0.30 0.09 0 5.00
148 INT279881 Negative_regulation of Gene_expression of PCDHB@ 1 0.05 0.09 0 5.00
149 INT279845 Regulation of Nipbl 1 0.39 0.28 0 5.00
150 INT279839 Regulation of Transcription of Pcdhb1 1 0.42 0.05 0 5.00
151 INT279857 Localization of Nipbl 1 0.65 0 0 5.00
152 INT279861 Positive_regulation of Gene_expression of Rnase1 1 0.15 0 0 5.00
153 INT279860 Binding of Pcdhb7 1 0.26 0.09 0 5.00
154 INT308911 Gene_expression of Elmaz1 1 0.16 0.08 0 5.00
155 INT279832 Gene_expression of Pcdhb1 1 0.72 0.06 0 5.00
156 INT279870 Transcription of Hbb-bh1 1 0.25 0 0 5.00
157 INT279833 Transcription of Pcdhb1 1 0.67 0 0 5.00
158 INT308915 Positive_regulation of Gene_expression of Gtf2i 1 0.36 0 0 5.00
159 INT272228 Localization of TGFBR1 1 0.34 0.74 0 5.00
160 INT308919 Localization of Gtf2i 1 0.73 0 0 5.00
161 INT279867 Binding of Rec8 1 0.01 0.81 0 5.00
162 INT279849 Binding of Pds5b 1 0.32 0.93 0 5.00
163 INT198907 Positive_regulation of Gene_expression of Lrp1 7 0.49 3.2 0 5.00
164 INT279883 Gene_expression of PCDHB@ 1 0.10 0.19 0 5.00
165 INT279855 Positive_regulation of Pcdhb1 1 0.47 0.08 0 5.00
166 INT350957 Binding of Psg27 1 0.04 0.93 0 5.00
167 INT279835 Regulation of Transcription of Hbb-bh1 1 0.16 0 0 5.00
168 INT328078 Regulation of Ppcs 1 0.24 0.71 0 5.00
169 INT272225 Localization of Tgfbr2 1 0.29 0.74 0 5.00
170 INT279837 Regulation of Gene_expression of Nipbl 1 0.39 0 0 5.00
171 INT279865 Transcription of Ctcf 1 0.36 0 0 5.00
172 INT279838 Protein_catabolism of Rec8 1 0.02 0.81 0 5.00
173 INT279859 Regulation of Pcdhb2 1 0.54 0 0 5.00
174 INT279863 Localization of Pds5a 1 0.47 0.93 0 5.00
175 INT279844 Localization of Pds5b 1 0.65 0.94 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox