D:Creutzfeldt Jakob Disease

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Disease Term
Synonyms Bovine Spongiform Encephalopathy, Cjd, Gerstmann Straussler Scheinker Disease, Mad Cow Disease, NEW VARIANT CJD, NEW VARIANT CREUTZFELDT JAKOB DISEASE, Prion Disease, Prion Diseases, Spongiform Encephalopathies, Spongiform Encephalopathy, VARIANT CREUTZFELDT JAKOB DISEASE
Documents 178
Hot Single Events 177
Hot Interactions 26

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Creutzfeldt Jakob Disease. They are ordered first by their relevance to Creutzfeldt Jakob Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT250153 Binding of PRNP and IKBKG 1 0.09 2.83 0.06 100.00
2 INT250150 Binding of IKBKG and SACM1L 1 0.00 2.78 0.06 100.00
3 INT251944 Binding of GH1 and PRNP 1 0.09 1.14 0.05 100.00
4 INT100597 Regulation of RPL21P132 Positive_regulation of IL6 1 0.01 0.45 0.53 99.56
5 INT327792 Binding of IGFALS and Alms1 1 0.00 1.15 0.11 98.64
6 INT100596 RPL21P132 Positive_regulation of TNF 1 0.00 0.43 0.5 97.64
7 INT100595 RPL21P132 Positive_regulation of IL6 1 0.01 0.43 0.49 97.64
8 INT306677 Binding of Mapt and Atxn3 1 0.07 0.49 0 96.24
9 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78 95.76
10 INT67527 MRXS5 Positive_regulation of Gene_expression of IL6 1 0.21 1.5 0.45 94.04
11 INT354482 Binding of PRNP and Prnp 1 0.16 0.88 0 93.04
12 INT297245 Prnp Positive_regulation of Notch1 1 0.21 0.73 0 91.84
13 INT287034 Pgp Regulation of Positive_regulation of Prnp 1 0.13 0.09 0 90.56
14 INT250151 Binding of GSS and MCM3 1 0.01 1.38 0.04 90.16
15 INT100594 DCSTAMP Positive_regulation of Gene_expression of IL6 1 0.03 0.24 0.41 86.64
16 INT67529 PTGDS Positive_regulation of Positive_regulation of IL6 1 0.30 0.69 0.29 86.08
17 INT260522 Binding of Myc and Prnp 1 0.30 0.35 0 85.76
18 INT260518 Binding of Prnp and Gopc 2 0.13 1.06 0 85.76
19 INT221653 Binding of Myc and Gopc 2 0.12 0.51 0.08 85.08
20 INT100598 PRNP Positive_regulation of Gene_expression of IL6 1 0.40 0.23 0.4 84.60
21 INT250152 Binding of APOE and UBE4B 1 0.21 1.2 0 84.08
22 INT229539 Cpz Negative_regulation of Localization of Prnp 1 0.05 0.58 0.07 83.48
23 INT229538 Cpz Negative_regulation of Positive_regulation of Prnp 1 0.05 0.58 0.07 83.48
24 INT67528 PTGER2 Positive_regulation of Gene_expression of IL6 2 0.10 1.38 0.45 81.16
25 INT297246 Binding of Notch1 and Ncstn 1 0.04 0.32 0.07 80.92
26 INT297244 Regulation of Binding of Notch1 and Ncstn 1 0.05 0.32 0.07 80.92
27 INT134698 Regulation of Prnp Positive_regulation of Nup214 1 0.26 1.18 0.14 75.00
28 INT134697 Prnp Positive_regulation of Nup214 1 0.44 1.18 0.13 75.00
29 INT230500 Il1 Positive_regulation of Gene_expression of Tnf 1 0.07 1.83 0.4 66.92
30 INT230501 Il1 Positive_regulation of Gene_expression of S100a8 1 0.01 1.82 0.39 66.92
31 INT271760 Binding of Psmb10 and Psmc3 1 0.00 0.29 0 60.80
32 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2 50.64
33 INT189200 Binding of CA2 and ITPR3 3 0.03 1.9 0.27 49.64
34 INT249600 IFNA1 Positive_regulation of Gene_expression of Cd40 1 0.49 1.13 0.52 48.92
35 INT189203 CHGB Regulation of CA2 1 0.04 0.95 0 44.56
36 INT189201 CHGB Regulation of Localization of CA2 1 0.04 0.95 0 44.56
37 INT174133 Binding of Igfals and Sod1 3 0.19 3 0.08 42.88
38 INT335953 Binding of BCL2 and Bad 1 0.14 0.37 0 11.80
39 INT335951 Binding of Bad and Tgif2lx1 1 0.00 0.37 0 11.80
40 INT210549 Binding of BCHE and Ache 1 0.01 0.82 0.12 5.08
41 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 5.00
42 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16 5.00
43 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84 5.00
44 INT275851 PES1 Negative_regulation of CP 1 0.01 1.96 1.83 5.00
45 INT91813 Binding of FAS and FASLG 4 0.23 9.89 0.99 5.00
46 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98 5.00
47 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89 5.00
48 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79 5.00
49 INT254199 Il10 Positive_regulation of Gene_expression of Socs3 2 0.06 0.75 0.63 5.00
50 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6 5.00
51 INT235975 Binding of AQP4 and IgG 2 0.04 4.11 0.53 5.00
52 INT235956 Binding of Aqp4 and NMO-IgG 1 0.04 4.53 0.5 5.00
53 INT264136 IFNA1 Positive_regulation of Socs3 1 0.01 0.38 0.46 5.00
54 INT183322 Binding of CNNM4 and RBM4B 1 0.12 0.59 0.46 5.00
55 INT264137 IFNA1 Positive_regulation of Socs1 1 0.01 0.38 0.46 5.00
56 INT189197 RASGRP1 Positive_regulation of JUN 1 0.07 1.26 0.43 5.00
57 INT275849 PES1 Positive_regulation of Gene_expression of TNFAIP1 1 0.01 1.28 0.42 5.00
58 INT264135 Socs1 Positive_regulation of Protein_catabolism of TOLLIP 1 0.00 0.33 0.41 5.00
59 INT231304 Prnp Negative_regulation of Grin2d 2 0.38 0.5 0.4 5.00
60 INT230499 Gene_expression of Il1rn Negative_regulation of Gene_expression of Icam1 1 0.01 0.85 0.36 5.00
61 INT324690 Binding of Traf6 and Ticam1 2 0.07 0.23 0.33 5.00
62 INT235971 Positive_regulation of Binding of Nqo1 and NMO-IgG 1 0.00 1.86 0.32 5.00
63 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3 5.00
64 INT235977 Binding of AQP4 and Ighg1 1 0.03 1.31 0.3 5.00
65 INT235957 Binding of Mog and Bcr 1 0.02 1.13 0.29 5.00
66 INT235962 Binding of Bcr and Trav6-3 1 0.00 1.12 0.29 5.00
67 INT235966 Binding of Mog and Trav6-3 1 0.01 1.07 0.29 5.00
68 INT327366 Binding of Fap and Ttr 1 0.33 2.9 0.28 5.00
69 INT235959 Nqo1 Positive_regulation of Localization of Aqp4 1 0.02 1.39 0.26 5.00
70 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 0.00 1.15 0.24 5.00
71 INT324694 Tlr4 Positive_regulation of Gene_expression of Pnoc 1 0.05 0.56 0.24 5.00
72 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24 5.00
73 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24 5.00
74 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24 5.00
75 INT235967 Binding of Ighm and Nqo1 1 0.00 1.45 0.23 5.00
76 INT189199 JUN Positive_regulation of KRT16 1 0.31 0.58 0.22 5.00
77 INT264134 Binding of IFNA1 and Tlr4 1 0.01 1.5 0.22 5.00
78 INT295430 BRD2 Positive_regulation of PLOD1 1 0.02 0.33 0.22 5.00
79 INT189196 RASGRP1 Positive_regulation of SP1 1 0.05 0.63 0.21 5.00
80 INT295434 BRD2 Positive_regulation of Gene_expression of GNRH1 1 0.02 0.07 0.2 5.00
81 INT327789 Binding of IgG and Alms1 1 0.01 1.1 0.17 5.00
82 INT327790 Binding of Nqo1 and Alms1 1 0.00 1.1 0.17 5.00
83 INT327791 Binding of AQP4 and Alms1 1 0.03 1.1 0.17 5.00
84 INT65677 Binding of CGA and FSHR 2 0.25 0.29 0.16 5.00
85 INT249599 Ifng Positive_regulation of Gene_expression of Il6 1 0.15 0.38 0.16 5.00
86 INT295433 Binding of PLOD1 and SCN5A 1 0.07 0.25 0.16 5.00
87 INT249598 Stat1 Positive_regulation of Gene_expression of Cd40 1 0.41 0.46 0.14 5.00
88 INT235961 Binding of Nqo1 and Aqp4 1 0.02 0.9 0.14 5.00
89 INT253929 Binding of Vcam1 and Cd99l2 1 0.00 0.61 0.13 5.00
90 INT324691 Tlr6 Positive_regulation of Rcvrn 1 0.01 0 0.12 5.00
91 INT287035 Gopc Positive_regulation of Prtn3 1 0.02 0.48 0.12 5.00
92 INT324695 Tlr6 Positive_regulation of Tlr2 1 0.14 0 0.12 5.00
93 INT278423 Binding of Emp1 and Map2 1 0.06 0.46 0.12 5.00
94 INT65676 Binding of CGA and PLOD1 3 0.23 1.68 0.1 5.00
95 INT249601 IFNA1 Negative_regulation of Gene_expression of Cd40 1 0.42 0.51 0.09 5.00
96 INT189195 Binding of C4A and C4B 1 0.14 2.45 0.09 5.00
97 INT253930 IFNA1 Positive_regulation of Cdc42ep3 1 0.00 0.65 0.08 5.00
98 INT207310 Pik3r1 Positive_regulation of Prnp 1 0.36 0.65 0.08 5.00
99 INT235964 Binding of Atp9a and Aqp4 1 0.01 0.55 0.08 5.00
100 INT189202 Binding of C4B and HAS2 1 0.02 1.25 0.05 5.00
101 INT216838 Binding of EPHB2 and Nfkb1 1 0.09 0.15 0.05 5.00
102 INT235963 Snta1 Regulation of Gene_expression of Aqp4 1 0.41 0.23 0.05 5.00
103 INT235969 Binding of Ighg1 and Nqo1 1 0.01 2.63 0.04 5.00
104 INT189198 Binding of C4A and SERPINF1 1 0.12 1.17 0.04 5.00
105 INT235968 NMO-IgG Positive_regulation of Nqo1 1 0.00 2.11 0.03 5.00
106 INT249597 Jak2 Positive_regulation of Phosphorylation of Stat1 1 0.20 0.13 0.03 5.00
107 INT324692 Binding of Cd14 and Sod1m 1 0.01 1.07 0.03 5.00
108 INT268187 Rab4a Regulation of Rab22a 1 0.15 0.12 0 5.00
109 INT268647 ATP2B3 Positive_regulation of Prnp 1 0.01 0.57 0 5.00
110 INT335952 Prnp Positive_regulation of can 1 0.17 0.58 0 5.00
111 INT268183 Gene_expression of Rab22a Negative_regulation of Gene_expression of Prnp 1 0.28 0.1 0 5.00
112 INT268186 Positive_regulation of Binding of Gpi1 and Erc1 1 0.01 0.17 0 5.00
113 INT316101 Binding of HIST1H4PS1 and ANGPTL5 1 0.01 0.28 0 5.00
114 INT260523 Binding of Cnp and Prnp 1 0.33 0.34 0 5.00
115 INT268199 Rab22a Regulation of Trf 1 0.11 0.17 0 5.00
116 INT217402 Binding of Bace1 and PSENEN 1 0.02 0.72 0 5.00
117 INT268192 Gene_expression of Rab22a Positive_regulation of Protein_catabolism of Prnp 1 0.30 0.08 0 5.00
118 INT260519 Binding of Prnp and Scarb1 1 0.41 0.21 0 5.00
119 INT268648 ATP2B3 Regulation of ATP2B3 Positive_regulation of Prnp 1 0.00 0.57 0 5.00
120 INT217399 Binding of Bace1 and Ncstn 1 0.05 0.72 0 5.00
121 INT268191 Rab4a Regulation of Gene_expression of Prnp 1 0.23 0.22 0 5.00
122 INT324696 Binding of Myd88 and Mapk10 1 0.05 0.68 0 5.00
123 INT307306 Gene_expression of COMP Positive_regulation of CALR 1 0.27 0.99 0 5.00
124 INT210548 SCARA3 Regulation of Tenc1 1 0.03 0 0 5.00
125 INT335950 Negative_regulation of Prnp Positive_regulation of can 1 0.16 0.59 0 5.00
126 INT307305 Gene_expression of COMP Positive_regulation of Positive_regulation of CALR 1 0.27 0.41 0 5.00
127 INT260520 Binding of Myc and Scarb1 1 0.33 0.16 0 5.00
128 INT268197 Gene_expression of Rab22a Regulation of Prnp 1 0.29 0.08 0 5.00
129 INT217398 Binding of Psen2 and Bace1 1 0.12 1.44 0 5.00
130 INT268184 Prnp Regulation of Gene_expression of Rab22a 1 0.34 0.17 0 5.00
131 INT268201 Tg(CAG-EGFP)D4Nagy Regulation of Prnp 1 0.01 0.22 0 5.00
132 INT268198 Prnp Positive_regulation of Erc1 1 0.04 0.26 0 5.00
133 INT268194 Erc1 Positive_regulation of Gene_expression of Prnp 1 0.05 0.2 0 5.00
134 INT307307 COMP Positive_regulation of EREG 1 0.01 0.46 0 5.00
135 INT268190 Gene_expression of Rab22a Negative_regulation of Prnp 1 0.32 0.08 0 5.00
136 INT217400 Binding of Psen1 and Bace1 1 0.17 1.43 0 5.00
137 INT268177 Rab4a Regulation of Prnp 1 0.14 0.22 0 5.00
138 INT268182 Positive_regulation of Binding of Prnp and Erc1 1 0.06 0.1 0 5.00
139 INT295432 FSHR Positive_regulation of PCOS1 1 0.06 1.24 0 5.00
140 INT217396 Binding of Abca1 and App 1 0.26 0.83 0 5.00
141 INT235960 Binding of Aqp4 and H47 1 0.01 0.13 0 5.00
142 INT307309 Binding of CALR and EREG 1 0.00 0.83 0 5.00
143 INT268189 Binding of Gpi1 and Erc1 1 0.01 0.17 0 5.00
144 INT268188 Binding of Prnp and Erc1 1 0.04 0.27 0 5.00
145 INT268185 Rab22a Negative_regulation of Gene_expression of Prnp 1 0.32 0.08 0 5.00
146 INT304270 Binding of Apoa1 and Scarb1 1 0.00 0.39 0 5.00
147 INT268181 Binding of Trf and Erc1 1 0.02 0.07 0 5.00
148 INT295431 FSHR Positive_regulation of CGA 1 0.29 0.27 0 5.00
149 INT307310 Binding of CALR and COMP 1 0.28 0.82 0 5.00
150 INT268179 Negative_regulation of Binding of Trf and Erc1 1 0.03 0.07 0 5.00
151 INT268195 Rab22a Negative_regulation of Prnp 1 0.44 0.09 0 5.00
152 INT268176 Positive_regulation of Erc1 Positive_regulation of Gene_expression of Prnp 1 0.06 0.2 0 5.00
153 INT217397 Binding of Bace1 and Alph1 1 0.02 0.73 0 5.00
154 INT268646 Prnp Positive_regulation of PRNP 1 0.08 0.42 0 5.00
155 INT307308 Binding of COMP and EREG 1 0.01 0.41 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Creutzfeldt Jakob Disease. They are ordered first by their pain relevance and then by number of times they were reported in Creutzfeldt Jakob Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5 100.00
2 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25 100.00
3 INT69570 Binding of Prnp 75 0.48 44.26 4.37 100.00
4 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11 100.00
5 INT167203 Binding of PRNP 25 0.48 20.09 1.84 100.00
6 INT180382 Gene_expression of Fcgr3 9 0.34 7.94 1.1 100.00
7 INT141131 Positive_regulation of Gene_expression of PRNP 12 0.61 16.6 1.36 100.00
8 INT100601 Localization of PRNP 17 0.66 13.61 0.71 100.00
9 INT85621 Regulation of PRNP 16 0.60 8.7 1.15 100.00
10 INT119348 Binding of IKBKG 7 0.15 4.03 1.14 100.00
11 INT251949 Negative_regulation of Gene_expression of PRNP 6 0.43 4.16 0.3 100.00
12 INT115708 Phosphorylation of PRNP 2 0.71 1.61 0.26 100.00
13 INT175417 Binding of SACM1L 8 0.29 6.06 0.22 100.00
14 INT251490 Localization of TSE2 1 0.04 1.71 0 100.00
15 INT53443 Gene_expression of IKBKG 15 0.65 7.5 2.71 100.00
16 INT335949 Positive_regulation of Positive_regulation of PRNP 2 0.25 0.82 0.29 100.00
17 INT69569 Positive_regulation of Prnp 175 0.70 96.31 13.34 99.98
18 INT204737 Negative_regulation of Gene_expression of Prnp 32 0.59 18.96 1.03 99.98
19 INT327778 Positive_regulation of Regulation of AQP4 1 0.37 2.84 0.07 99.92
20 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 99.84
21 INT50057 Regulation of Notch1 3 0.39 0.87 2.14 99.84
22 INT93936 Gene_expression of Pgp 10 0.59 3.43 3.04 99.76
23 INT287025 Negative_regulation of Gene_expression of Pgp 1 0.30 0.1 0 99.76
24 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 99.72
25 INT22785 Negative_regulation of PRNP 12 0.57 5.09 1.57 99.70
26 INT102255 Regulation of Prnp 35 0.62 18.97 3.25 99.58
27 INT105536 Regulation of Myoz1 6 0.17 3.45 2.01 99.58
28 INT9660 Regulation of TNF 363 0.62 312.94 139.99 99.56
29 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 99.56
30 INT9210 Regulation of IL6 166 0.62 125.61 49.95 99.56
31 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 99.56
32 INT77427 Regulation of Negative_regulation of CPOX 17 0.26 10.03 6.15 99.56
33 INT157960 Regulation of AQP4 11 0.48 21.36 3.06 99.52
34 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 99.48
35 INT140413 Gene_expression of AQP4 113 0.78 139.25 25.53 99.44
36 INT251679 Negative_regulation of Gene_expression of AQP4 2 0.38 10.37 0.77 99.44
37 INT250272 Positive_regulation of Gene_expression of AQP4 11 0.54 9.79 1.85 99.44
38 INT140414 Positive_regulation of AQP4 25 0.64 23.43 2.47 99.44
39 INT250282 Negative_regulation of AQP4 32 0.54 32.96 9.07 99.44
40 INT135040 Regulation of Gene_expression of Prnp 30 0.62 10.52 2.45 99.36
41 INT354480 Regulation of Gene_expression of PRNP 1 0.39 1.96 0.08 99.32
42 INT17511 Negative_regulation of PRTN3 19 0.41 12 3.3 99.32
43 INT271732 Negative_regulation of Psmb10 6 0.03 5.77 0.26 99.22
44 INT234160 Localization of Igfals 4 0.16 3.8 0.74 99.16
45 INT49129 Positive_regulation of GFAP 35 0.69 28.78 10.38 99.12
46 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55 99.08
47 INT327786 Negative_regulation of Gene_expression of AQP1 3 0.29 4.21 0.44 99.08
48 INT211054 Positive_regulation of AQP1 3 0.33 4.53 1.41 99.08
49 INT166889 Positive_regulation of Gene_expression of AQP1 10 0.70 6.43 0.99 99.08
50 INT2611 Negative_regulation of AQP1 17 0.39 10.04 2.15 99.08
51 INT246641 Gene_expression of YWHAQ 5 0.58 3 0.22 99.04
52 INT50673 Positive_regulation of Gene_expression of CPOX 156 0.54 97.31 37.03 98.92
53 INT48390 Negative_regulation of Localization of CSF2 10 0.51 7.39 3.28 98.88
54 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57 98.80
55 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 98.64
56 INT18156 Gene_expression of Fap 18 0.73 27.02 1.46 98.46
57 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 98.32
58 INT102254 Positive_regulation of Gene_expression of Prnp 72 0.70 38.11 4.81 98.28
59 INT204736 Gene_expression of Nidds 1 0.65 1.57 0.13 98.22
60 INT66198 Negative_regulation of Gene_expression of Gfap 13 0.59 10.33 3.41 98.12
61 INT66199 Negative_regulation of Gfap 14 0.46 6.88 2.57 98.12
62 INT66201 Negative_regulation of GFAP 5 0.57 3.48 0.94 98.12
63 INT25607 Binding of Il1 82 0.47 64.4 23.9 98.00
64 INT38147 Positive_regulation of Mixl1 3 0.26 1.31 0.32 98.00
65 INT69572 Localization of Prnp 96 0.81 38.11 5.45 97.84
66 INT14690 Localization of CSF2 124 0.80 85.17 27.26 97.84
67 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37 97.68
68 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 97.56
69 INT169748 Positive_regulation of Gene_expression of Aqp4 38 0.69 34.29 3.79 97.56
70 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 97.52
71 INT119187 Gene_expression of HLA-DRB5 5 0.02 4.47 1.18 97.44
72 INT178338 Gene_expression of Tbx15 50 0.65 38.65 12.19 97.44
73 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 97.18
74 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63 97.08
75 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 97.04
76 INT78210 Gene_expression of MCC 7 0.65 1.8 0.98 96.96
77 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 96.86
78 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 96.64
79 INT188122 Negative_regulation of Hras1 12 0.02 8.38 0.21 96.40
80 INT75299 Binding of Atxn3 8 0.43 5.3 0.26 96.24
81 INT14031 Gene_expression of Npy 107 0.78 36.48 35.4 96.20
82 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 96.20
83 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7 96.20
84 INT15652 Positive_regulation of ENO2 37 0.68 33.39 5.02 96.16
85 INT225965 Localization of Aqp4 26 0.81 18.85 3.75 95.96
86 INT235947 Regulation of Localization of Aqp4 1 0.37 1.25 0.22 95.96
87 INT69571 Positive_regulation of Positive_regulation of Prnp 6 0.70 5.88 0.67 95.64
88 INT102747 Gene_expression of Hmbs 17 0.78 10.53 1.34 95.52
89 INT102744 Positive_regulation of Gene_expression of Hmbs 4 0.70 2.97 0.35 95.52
90 INT297236 Negative_regulation of Gsi1 1 0.06 0.92 0.22 95.48
91 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 95.16
92 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 94.84
93 INT102253 Negative_regulation of Prnp 75 0.59 24.23 2.62 94.72
94 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 94.40
95 INT293047 Protein_catabolism of PRNP 1 0.57 2 0.03 94.24
96 INT90077 Gene_expression of Casp1 29 0.76 20.79 6.26 94.24
97 INT297241 Positive_regulation of Positive_regulation of Notch1 2 0.40 1.02 0.2 94.12
98 INT255619 Regulation of CASZ1 2 0.03 0.9 0.06 93.84
99 INT116249 Positive_regulation of LARS 6 0.39 4.16 0.71 93.76
100 INT21646 Positive_regulation of Npy 40 0.70 31.31 13.57 93.72
101 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 93.68
102 INT158313 Positive_regulation of Psd 3 0.39 1.96 0.43 93.68
103 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 93.40
104 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 92.96
105 INT190664 Regulation of Binding of Prnp 3 0.52 4.29 0.1 92.92
106 INT190666 Positive_regulation of Binding of Prnp 2 0.50 1.87 0 92.92
107 INT207304 Positive_regulation of Protein_catabolism of Prnp 9 0.69 2.08 0.09 92.08
108 INT123076 Gene_expression of Cacna1c 7 0.37 1.91 1.56 91.92
109 INT124164 Protein_catabolism of Prnp 20 1.00 8.58 0.44 91.72
110 INT44255 Gene_expression of Prid1 1 0.52 0.94 0 91.52
111 INT102901 Regulation of Gene_expression of Th 12 0.60 2.42 3.22 91.48
112 INT135044 Regulation of Gene_expression of Ache 2 0.31 0.85 0.58 91.48
113 INT135043 Regulation of Gene_expression of Tg(MMTV-Notch4)3Rnc 2 0.10 0.28 0.43 91.48
114 INT135041 Regulation of Gene_expression of Cd1 1 0.40 0.28 0.43 91.48
115 INT64171 Regulation of CPOX 109 0.36 55.36 32.96 91.44
116 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95 91.04
117 INT67037 Gene_expression of Sod1 121 0.78 59.32 7.99 90.96
118 INT30817 Gene_expression of Th 142 0.76 33.56 38.12 90.88
119 INT1753 Gene_expression of Ache 38 0.78 15.31 4.58 90.88
120 INT135042 Gene_expression of Tg(MMTV-Notch4)3Rnc 9 0.15 5.17 1.13 90.88
121 INT135039 Gene_expression of Cd1 11 0.60 5.66 1.05 90.88
122 INT12082 Localization of IL6 365 0.81 241.78 105.78 90.84
123 INT151668 Positive_regulation of Maob 1 0.61 3.26 0.6 90.68
124 INT334211 Positive_regulation of Gene_expression of TARDBP 1 0.32 3.03 0 89.96
125 INT264685 Gene_expression of TARDBP 4 0.61 8.8 0.31 89.40
126 INT334213 Transcription of TARDBP 1 0.24 0.98 0 89.40
127 INT268144 Negative_regulation of Localization of Prnp 3 0.37 0.71 0 89.20
128 INT94122 Negative_regulation of Mmp23 21 0.37 15.81 8.03 89.16
129 INT132997 Localization of Mmp9 59 0.80 45.9 17.61 89.16
130 INT95767 Negative_regulation of Mmp9 72 0.57 49.14 17.1 89.16
131 INT198875 Localization of Mmp23 4 0.07 2.05 0.88 89.16
132 INT158738 Binding of Pgr 9 0.28 3.49 0.61 89.04
133 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 88.92
134 INT188726 Positive_regulation of IGLV3-1 4 0.49 2.39 0.07 88.84
135 INT275621 Positive_regulation of Atcay 3 0.06 2.15 0.04 88.72
136 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 88.72
137 INT190665 Gene_expression of Mixl1 4 0.35 2.54 0.2 87.60
138 INT155889 Binding of Nps 22 0.42 9.79 2.6 87.48
139 INT173693 Localization of Gopc 249 0.65 70.49 38.81 87.48
140 INT86002 Binding of PBCA 3 0.11 0.75 0.03 87.48
141 INT56342 Gene_expression of TTR 34 0.78 16.5 2.05 87.28
142 INT259802 Positive_regulation of Tbx15 2 0.45 1.87 0.09 87.28
143 INT59449 Negative_regulation of Timp1 76 0.42 54.86 26.99 87.24
144 INT100603 Gene_expression of DCSTAMP 7 0.22 3.05 2.25 86.64
145 INT240690 Positive_regulation of Binding of PRNP 1 0.07 0.53 0 86.44
146 INT182454 Binding of Tg(CAG-EGFP)D4Nagy 28 0.29 3.29 1.11 86.40
147 INT250157 Gene_expression of GSS 2 0.22 1.54 0.1 85.84
148 INT108761 Localization of Alms1 24 0.70 13.92 3.74 85.40
149 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37 85.24
150 INT275871 Positive_regulation of CLPS 1 0.08 0.26 0.08 85.20
151 INT190667 Binding of PNMA2 1 0.08 2.37 0.66 84.92
152 INT190663 Binding of Mixl1 1 0.19 1.08 0 84.92
153 INT184742 Binding of MAP2 6 0.37 3.29 0.06 84.92
154 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93 84.16
155 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 84.08
156 INT196207 Negative_regulation of Tbx15 2 0.42 0.86 0 83.72
157 INT73362 Negative_regulation of Abcb1a 46 0.59 8.78 17.81 83.36
158 INT60957 Negative_regulation of Abcb1b 18 0.57 6 4.73 83.36
159 INT107904 Positive_regulation of Gene_expression of BCL2L11 3 0.53 2.22 1.24 83.28
160 INT6852 Localization of TNF 883 0.81 705.95 270.84 83.20
161 INT107905 Gene_expression of BCL2L11 9 0.75 7.58 1.92 82.72
162 INT85639 Positive_regulation of Tg(CAG-EGFP)D4Nagy 95 0.43 24.83 15.69 82.64
163 INT152885 Localization of Itgam 16 0.73 7.62 1.43 82.64
164 INT147668 Negative_regulation of Positive_regulation of Tg(CAG-EGFP)D4Nagy 2 0.22 0.4 0.1 82.64
165 INT137204 Localization of Itgax 6 0.70 3.86 0.67 82.32
166 INT4437 Positive_regulation of ABCB7 11 0.68 11.26 1.33 82.16
167 INT172445 Positive_regulation of Gene_expression of Myc 58 0.70 39.62 0.25 81.96
168 INT21794 Positive_regulation of Gene_expression of Npy 20 0.70 8.44 9.3 81.88
169 INT172452 Gene_expression of Myc 121 0.78 69.56 1.36 81.52
170 INT100602 Gene_expression of RPL21P132 2 0.02 0.77 0.42 81.44
171 INT297242 Transcription of Notch1 1 0.19 0.25 0 81.40
172 INT287031 Positive_regulation of Negative_regulation of Prnp 1 0.46 0.16 0.03 80.76
173 INT91899 Binding of Sod1 17 0.47 11.56 2.63 80.56
174 INT174130 Positive_regulation of Binding of Sod1 1 0.48 0.72 0 80.56
175 INT36054 Transcription of IL1B 53 0.72 32.64 17.31 80.48
176 INT36055 Positive_regulation of Transcription of IL1B 9 0.49 6.24 2.21 80.48
177 INT293427 Gene_expression of Gm4053 1 0.01 0.89 0 80.12
178 INT35406 Localization of Tnf 94 0.81 64.63 31.65 79.92
179 INT61626 Transcription of IL6 73 0.72 42.04 17.86 79.76
180 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 79.64
181 INT170051 Positive_regulation of Gene_expression of Gopc 150 0.43 56.75 16.93 79.64
182 INT57192 Binding of Ltp 43 0.41 17.48 24.96 79.52
183 INT19775 Localization of Il1 183 0.78 145.5 50.91 79.48
184 INT14572 Binding of INS 205 0.48 175.43 13.38 79.40
185 INT20381 Localization of Il2 71 0.77 34.23 13.03 79.24
186 INT11937 Localization of Il6 228 0.81 139.83 64.39 79.00
187 INT240689 Gene_expression of FCMTE1 3 0.15 1.31 0 78.92
188 INT5957 Positive_regulation of Cpe 65 0.69 21.07 51.22 78.92
189 INT133156 Binding of Cd40 77 0.48 45.92 13.77 78.64
190 INT100599 Localization of Ghrhr 3 0.78 1.54 1.17 78.48
191 INT14030 Regulation of Gene_expression of Npy 7 0.47 5.58 2.49 78.48
192 INT208860 Gene_expression of Psmb10 5 0.04 1.71 0.44 78.24
193 INT271727 Positive_regulation of Gene_expression of Psmb10 1 0.03 0.48 0 78.24
194 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 78.16
195 INT78284 Positive_regulation of PTPRC 40 0.49 27.17 3.45 77.96
196 INT23775 Regulation of S100B 24 0.62 16.75 2.57 77.84
197 INT58563 Negative_regulation of S100B 13 0.51 11.75 1.77 77.84
198 INT264130 Localization of SERPINA3 2 0.78 3.13 0.39 77.64
199 INT18360 Regulation of MRXS5 11 0.32 7.07 2.17 77.00
200 INT193863 Gene_expression of Ncstn 7 0.29 3.88 0.66 76.60
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