D:Critical Illness

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Disease Term
Synonyms Critical Illnesses, Critically Ill, Illness Critical, ILLNESSES CRITICAL
Documents 1817
Hot Single Events 200
Hot Interactions 40

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Critical Illness. They are ordered first by their relevance to Critical Illness and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT202233 IGFBP1 Regulation of IGF1 1 0.22 0.19 0.04 99.72
2 INT202245 IGFBP1 Regulation of Igfbp1 1 0.12 0.19 0.04 99.72
3 INT224404 Binding of GYPC and PYY 1 0.04 1.48 1.42 99.46
4 INT203017 Binding of CCK and PYY 1 0.38 0.62 0.43 98.96
5 INT220387 Gh1 Regulation of Localization of Igf1 1 0.05 0.3 0.17 97.18
6 INT316131 IL10 Regulation of Regulation of HLA-DRA 1 0.09 1.31 0.09 96.84
7 INT224403 Binding of CCK and GYPC 1 0.04 0.83 0.77 96.36
8 INT220390 TNF Positive_regulation of Gene_expression of Igfbp1 1 0.02 0.29 0.27 94.72
9 INT220380 Il6 Positive_regulation of Gene_expression of Igfbp1 1 0.09 0.29 0.27 94.08
10 INT298733 INS Regulation of ACSBG1 1 0.00 0.97 0.05 94.08
11 INT298734 USE1 Regulation of ACSBG1 1 0.00 0.97 0.05 94.08
12 INT220381 Il1a Positive_regulation of Gene_expression of Igfbp1 1 0.01 0.28 0.27 93.60
13 INT203018 GHRH Positive_regulation of Localization of PYY 1 0.01 0.81 0.12 93.48
14 INT316132 IL10 Regulation of MARCH1 1 0.11 2.12 0.17 92.92
15 INT316122 IL10 Regulation of Gene_expression of MARCH1 1 0.19 2.12 0.17 92.92
16 INT316125 IL10 Regulation of KRT20 1 0.00 1.06 0.08 92.92
17 INT316127 IL10 Regulation of UBR1 1 0.00 1.06 0.08 92.92
18 INT328299 Binding of GHRH and GHS 1 0.07 2.21 0.31 92.28
19 INT203016 CCK Positive_regulation of Localization of PYY 3 0.68 1.19 1.17 92.20
20 INT203015 CCK Regulation of Localization of PYY 1 0.24 0.61 0.28 92.20
21 INT304495 Trib3 Positive_regulation of Mapk1 1 0.02 1.4 0.35 90.92
22 INT262289 Regulation of Binding of PPIG and CC2D1A 1 0.01 1.52 0.13 90.84
23 INT262290 Binding of PPIG and CC2D1A 1 0.01 1.52 0.13 90.44
24 INT316111 APC Negative_regulation of SAE1 1 0.04 1.21 0.22 86.00
25 INT316129 Binding of HLA-DRA and IL10 1 0.12 3.1 0.17 85.92
26 INT202247 Binding of IGF1 and Igfbp1 1 0.16 0.21 0 85.20
27 INT220385 Binding of Igf1 and Gnrhr 1 0.05 0.99 0.14 84.32
28 INT220386 Binding of Gh1 and Igf1 1 0.07 0.99 0.14 84.32
29 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9 84.00
30 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01 82.32
31 INT294780 IL6 Positive_regulation of IL10 2 0.10 1.26 0.39 82.32
32 INT323654 Igfbp1 Negative_regulation of Binding of Igf1 and Igfbp1 1 0.21 1.14 0.29 81.68
33 INT323653 Binding of Igf1 and Igfbp1 1 0.20 1.14 0.29 81.68
34 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66 81.60
35 INT334948 IL6 Positive_regulation of IL6 Regulation of IL1RN 1 0.17 1.11 0.35 81.60
36 INT334951 IL6 Positive_regulation of Regulation of IL1RN 1 0.23 1.11 0.35 81.60
37 INT334947 IL6 Regulation of IL6 Positive_regulation of IL1RN 1 0.10 1.11 0.35 81.60
38 INT334949 IL6 Regulation of Regulation of IL1RN 1 0.13 1.11 0.35 81.60
39 INT334950 IL6 Regulation of IL1RN 1 0.13 1.11 0.35 81.60
40 INT323611 Il1 Regulation of Hmgb1 1 0.17 2.36 0.55 80.56
41 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98 79.24
42 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 0.57 1.4 0.76 78.56
43 INT173112 IL1B Positive_regulation of Gene_expression of VCAM1 2 0.43 1.34 0.76 77.92
44 INT1151 Binding of CCK and GAST 7 0.49 0.73 3.08 76.48
45 INT273244 Binding of VCF and Del(7)Tyr<c-23DVT>-p 1 0.00 2.94 0.55 75.00
46 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46 70.64
47 INT222283 Negative_regulation of Casp1 Negative_regulation of Il1a 1 0.00 0.78 0.46 69.84
48 INT224406 INS Regulation of Localization of PYY 1 0.11 0.27 0.27 65.12
49 INT306019 Binding of Tlr4 and LY96 1 0.06 0.91 0.49 64.68
50 INT224405 INS Regulation of Localization of CCK 1 0.12 0.27 0.27 64.56
51 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84 61.48
52 INT283259 MIR146B Positive_regulation of Gene_expression of IRF6 1 0.01 0.95 0 56.92
53 INT283254 MIR150 Positive_regulation of Gene_expression of IRF6 1 0.04 0.95 0 56.92
54 INT283258 MIR342 Positive_regulation of Gene_expression of IRF6 1 0.02 0.96 0 56.92
55 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34 52.04
56 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55 51.84
57 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31 51.84
58 INT345011 Binding of GSN and PTAFR 1 0.09 0.83 0.12 51.80
59 INT177672 Vmn1r51 Positive_regulation of Localization of Ptgis 1 0.00 0.24 0.03 51.36
60 INT177671 Vmn1r51 Positive_regulation of Localization of Nppa 1 0.01 0.24 0.03 51.36
61 INT182021 Binding of TNF and Il6 2 0.04 0.74 0.53 51.12
62 INT182100 Positive_regulation of Binding of TNF and Il6 1 0.03 0.66 0.41 51.12
63 INT316110 Binding of APC and SAE1 1 0.03 1.16 0.2 50.88
64 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 50.80
65 INT283256 MIR150 Regulation of Gene_expression of MYB 1 0.12 0.83 0 50.68
66 INT81716 ITGAL Regulation of ITGB2 2 0.30 1.24 0.78 50.00
67 INT170127 Binding of ITGAL and PECAM1 2 0.01 2.71 0.75 50.00
68 INT170128 Binding of ITGAL and ITGB2 2 0.04 1.6 0.28 50.00
69 INT265919 Binding of PLEK and Adp 1 0.01 0.38 0.11 50.00
70 INT170121 ITGAL Regulation of CD44 1 0.07 1.07 0 50.00
71 INT170119 PECAM1 Regulation of Positive_regulation of ITGAL 1 0.01 1.07 0 50.00
72 INT170124 ITGAM Regulation of ITGB2 1 0.04 1.07 0 50.00
73 INT170120 PECAM1 Regulation of ITGAM 1 0.00 1.07 0 50.00
74 INT170118 PECAM1 Regulation of CD44 1 0.01 1.07 0 50.00
75 INT170123 ITGAL Regulation of Positive_regulation of PECAM1 1 0.01 1.07 0 50.00
76 INT170125 ITGAM Regulation of Positive_regulation of PECAM1 1 0.01 1.07 0 50.00
77 INT170126 PECAM1 Regulation of ITGB2 1 0.01 1.07 0 50.00
78 INT170116 ITGAM Regulation of CD44 1 0.07 1.07 0 50.00
79 INT170114 ITGAM Regulation of Positive_regulation of ITGAL 1 0.04 1.07 0 50.00
80 INT170115 PECAM1 Regulation of ITGAL 1 0.00 1.07 0 50.00
81 INT115261 Gene_expression of Nos2 Positive_regulation of Positive_regulation of Npr1 1 0.05 0.67 0.31 46.40
82 INT175016 Binding of REN and S100A6 2 0.11 1.13 0.37 46.12
83 INT311811 Binding of REN and RASGRP1 1 0.16 0.68 0.08 45.92
84 INT158391 Oxt Positive_regulation of Localization of Nppa 2 0.27 0.64 0.03 44.88
85 INT220382 Cotl1 Positive_regulation of Binding of Gh1 1 0.01 0.38 0.03 42.68
86 INT34772 GH1 Regulation of IGF1 2 0.32 0.95 0.69 34.24
87 INT262307 CAPNS1 Regulation of TAF9 1 0.04 1.23 0.33 33.76
88 INT220383 Binding of Igf1 and Cotl1 1 0.03 0.37 0.22 29.72
89 INT3616 Trh Positive_regulation of Localization of Gh1 4 0.73 0.49 0.36 26.12
90 INT270316 Binding of AMBP and NHS 1 0.20 0.91 0 23.68
91 INT179234 Binding of SERPINA6 and ELANE 1 0.01 0.22 0.12 22.88
92 INT213207 Negative_regulation of ASAP2 Negative_regulation of PVR 1 0.01 0.45 0.04 16.44
93 INT213206 ASAP2 Negative_regulation of PVR 1 0.01 0.44 0.04 16.04
94 INT293014 IRF6 Positive_regulation of Localization of CA2 1 0.04 0.71 1.02 12.52
95 INT293008 IL8 Positive_regulation of Localization of CA2 1 0.11 0.71 1.01 12.20
96 INT220388 Gh1 Regulation of Cish 1 0.03 0.29 0.28 10.80
97 INT283252 IRF6 Regulation of MIR155 1 0.01 1.04 0.03 6.76
98 INT283255 IRF6 Regulation of MIR15B 1 0.00 1.04 0.03 6.76
99 INT177958 IGHE Positive_regulation of TNF 1 0.03 2.23 0 6.00
100 INT177959 Positive_regulation of IGHE Positive_regulation of TNF 1 0.03 2.23 0 6.00
101 INT283260 TNF Positive_regulation of TNF Regulation of MIR15B 1 0.01 1.03 0.03 5.40
102 INT283253 TNF Regulation of MIR15B 1 0.01 1.03 0.03 5.40
103 INT283257 TNF Regulation of MIR155 1 0.04 1.03 0.03 5.40
104 INT2161 Gnrh1 Positive_regulation of Localization of LH 33 0.73 0.87 14.34 5.00
105 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2 5.00
106 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18 5.00
107 INT20133 Trh Positive_regulation of Localization of Prl 23 0.78 2.04 5.44 5.00
108 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 5.00
109 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29 5.00
110 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47 5.00
111 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
112 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79 5.00
113 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95 5.00
114 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 5.00
115 INT9786 Gnrh1 Regulation of LH 7 0.40 0.58 1.82 5.00
116 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68 5.00
117 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55 5.00
118 INT293009 IRF6 Positive_regulation of Positive_regulation of CA2 1 0.04 0.66 1.49 5.00
119 INT293013 IL8 Positive_regulation of Positive_regulation of CA2 1 0.12 0.66 1.49 5.00
120 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25 5.00
121 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23 5.00
122 INT62368 Gal Positive_regulation of Localization of LH 3 0.36 0 1.2 5.00
123 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2 5.00
124 INT222516 Binding of Calcrl and Ramp1 5 0.17 0.11 1.12 5.00
125 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11 5.00
126 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 5.00
127 INT316128 TCF21 Negative_regulation of Gene_expression of HLA-DRA 1 0.07 0.13 0.99 5.00
128 INT36186 Npy Positive_regulation of Localization of Gnrh1 4 0.75 0.09 0.96 5.00
129 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95 5.00
130 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9 5.00
131 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82 5.00
132 INT293011 GPM6A Regulation of GOPC 1 0.00 0 0.81 5.00
133 INT73775 Binding of GH1 and GHR 4 0.35 0.68 0.8 5.00
134 INT222528 Abat Positive_regulation of Gene_expression of Gh1 1 0.01 0 0.75 5.00
135 INT222432 Binding of Tlr4 and Cd14 1 0.02 0.74 0.71 5.00
136 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71 5.00
137 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69 5.00
138 INT32715 Prl Regulation of Localization of LH 2 0.34 0.09 0.68 5.00
139 INT60283 Positive_regulation of Gnrh1 Regulation of LH 2 0.31 0 0.68 5.00
140 INT222552 Abat Regulation of Gene_expression of Gh1 1 0.00 0 0.67 5.00
141 INT293010 ELANE Regulation of Localization of LTF 1 0.00 0.54 0.67 5.00
142 INT306020 Binding of LBP and Tlr4 1 0.13 0.34 0.66 5.00
143 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66 5.00
144 INT220145 HPSE Negative_regulation of Gene_expression of CRH 1 0.01 0.92 0.64 5.00
145 INT222492 Ngf Positive_regulation of Gene_expression of Prl 1 0.24 0 0.62 5.00
146 INT3617 Trh Regulation of Localization of Gh1 3 0.65 0.55 0.62 5.00
147 INT27067 Crh Positive_regulation of Localization of Avp 3 0.18 0.46 0.61 5.00
148 INT32747 Avp Positive_regulation of Localization of Pomc 4 0.16 1.92 0.61 5.00
149 INT179203 NLRP1 Regulation of Gene_expression of TNF 1 0.31 1.73 0.6 5.00
150 INT222521 Vip Positive_regulation of Localization of Ngf 1 0.14 0.08 0.6 5.00
151 INT60536 Gnrh1 Positive_regulation of Localization of Prl 2 0.22 1.12 0.6 5.00
152 INT222554 Il1a Positive_regulation of Localization of Ngf 1 0.02 0.07 0.6 5.00
153 INT352496 AVP Regulation of Gene_expression of CRS 1 0.27 2.47 0.59 5.00
154 INT263454 Negative_regulation of IRF6 Positive_regulation of TNF 1 0.12 0.49 0.59 5.00
155 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58 5.00
156 INT284461 Gtf3a Positive_regulation of Gene_expression of IFN1@ 1 0.01 0.56 0.57 5.00
157 INT311766 INCENP Negative_regulation of Gene_expression of SLC1A3 1 0.04 0 0.55 5.00
158 INT215101 Hmgb1 Positive_regulation of Localization of Il6 4 0.16 1.18 0.54 5.00
159 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52 5.00
160 INT311767 INS Negative_regulation of Gene_expression of SLC1A3 1 0.52 0 0.52 5.00
161 INT222524 Abat Negative_regulation of Localization of Trh 1 0.02 0.16 0.51 5.00
162 INT254125 Binding of Bcl2a1a and Tlr4 Positive_regulation of Localization of Il6 1 0.00 1.23 0.5 5.00
163 INT254119 Binding of Bcl2a1a and Tlr4 1 0.01 1.34 0.49 5.00
164 INT253770 Hmgb1 Positive_regulation of Localization of Apex1 1 0.08 0.71 0.49 5.00
165 INT179237 Binding of SERPINA6 and POMC 1 0.03 1.15 0.49 5.00
166 INT300956 Il4 Negative_regulation of IL8 1 0.02 0.37 0.48 5.00
167 INT300960 Il4 Negative_regulation of IL1B 1 0.03 0.37 0.48 5.00
168 INT300957 Binding of IL13 and Il4 1 0.01 0.58 0.48 5.00
169 INT300959 Il4 Negative_regulation of TNF 1 0.03 0.37 0.48 5.00
170 INT300955 Il4 Negative_regulation of Il6 1 0.03 0.37 0.48 5.00
171 INT132792 IL4 Positive_regulation of IL6 4 0.28 1.81 0.47 5.00
172 INT322264 Binding of MPZ and TLR4 1 0.18 1.68 0.47 5.00
173 INT328385 Binding of GHS and Ghrl 1 0.15 1.89 0.45 5.00
174 INT254120 Aliq1 Positive_regulation of Tbce 1 0.00 0.68 0.43 5.00
175 INT328377 Binding of GAST and Ghrl 1 0.03 0.62 0.43 5.00
176 INT316121 IL10 Regulation of Gene_expression of HLA-DRA 1 0.09 0.46 0.42 5.00
177 INT293007 IRF6 Positive_regulation of ELANE 1 0.00 0 0.42 5.00
178 INT222490 Npy Positive_regulation of Localization of Gh1 1 0.02 0.06 0.41 5.00
179 INT290269 KNG1 Positive_regulation of Binding of MID1 1 0.02 1.06 0.41 5.00
180 INT290270 KNG1 Positive_regulation of MID1 1 0.02 1.06 0.41 5.00
181 INT222418 Tlr4 Positive_regulation of Gene_expression of Il1a 1 0.00 0.31 0.39 5.00
182 INT345006 CSF2 Regulation of GSN 1 0.16 0.82 0.39 5.00
183 INT345007 CSF2 Regulation of DBP 1 0.14 0.82 0.39 5.00
184 INT198652 F2 Positive_regulation of Gene_expression of CD36 1 0.03 1.32 0.37 5.00
185 INT304501 Binding of Ephb1 and Mapk1 1 0.18 0.69 0.36 5.00
186 INT179201 NLRP1 Regulation of Gene_expression of IL10 1 0.06 0.77 0.36 5.00
187 INT345012 GSN Regulation of CCBE1 1 0.00 0.82 0.36 5.00
188 INT345010 GSN Regulation of DBP 1 0.26 0.81 0.36 5.00
189 INT345009 DBP Regulation of CCBE1 1 0.00 0.81 0.36 5.00
190 INT179202 NLRP1 Regulation of Gene_expression of IL6 1 0.07 0.77 0.36 5.00
191 INT304505 Binding of Mapk1 and Uts2d 1 0.01 0.64 0.36 5.00
192 INT254123 Binding of Adora2b and Rai1 1 0.24 0.75 0.35 5.00
193 INT304532 Binding of Mdk and Mapk1 1 0.02 0.63 0.35 5.00
194 INT173111 IL1B Positive_regulation of VCAM1 1 0.31 1.32 0.35 5.00
195 INT304529 Negative_regulation of Binding of Mdk and Mapk1 1 0.02 0.63 0.35 5.00
196 INT198647 TNF Positive_regulation of HIF1A 1 0.03 2.97 0.34 5.00
197 INT344238 MCRS1 Regulation of TREX1 1 0.08 1.02 0.34 5.00
198 INT182126 IRF6 Positive_regulation of Gene_expression of SELE 1 0.03 0.86 0.34 5.00
199 INT198642 GPI Positive_regulation of TNF 1 0.03 0.98 0.33 5.00
200 INT253766 Binding of Apex1 and Tlr4 1 0.03 0.53 0.32 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Critical Illness. They are ordered first by their pain relevance and then by number of times they were reported in Critical Illness. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT214860 Binding of GYPC 10 0.36 11.18 0.74 100.00
2 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15 100.00
3 INT17110 Gene_expression of PSMD1 60 0.65 19.57 4.69 100.00
4 INT202950 Binding of Skap2 2 0.31 1.17 0.06 100.00
5 INT198663 Positive_regulation of HMGB1 14 0.52 11.41 1.58 100.00
6 INT138843 Binding of CC2D1A 19 0.33 33.06 1.25 100.00
7 INT203026 Negative_regulation of Gene_expression of PYY 1 0.40 0.29 0.39 100.00
8 INT89337 Negative_regulation of Gene_expression of CCK 4 0.58 3.14 3.21 100.00
9 INT203020 Positive_regulation of PYY 37 0.68 18.81 9.63 99.96
10 INT46714 Positive_regulation of TNNC1 76 0.67 75.99 6.66 99.92
11 INT2463 Localization of CCK 101 0.81 37.54 47.59 99.92
12 INT2885 Positive_regulation of Localization of CCK 19 0.70 9.92 8.94 99.92
13 INT203019 Positive_regulation of Gene_expression of PYY 1 0.41 0.75 0.04 99.92
14 INT183755 Localization of GYPC 4 0.56 3.91 1.42 99.88
15 INT2884 Positive_regulation of CCK 66 0.69 25.25 30.6 99.84
16 INT128369 Localization of PYY 27 0.79 10.39 7.06 99.84
17 INT9552 Positive_regulation of TNNI3 209 0.70 128.67 19.15 99.84
18 INT2406 Gene_expression of CCK 85 0.78 28.04 46.67 99.84
19 INT164926 Regulation of GYPC 9 0.46 16.66 2.04 99.84
20 INT203021 Positive_regulation of Localization of PYY 8 0.47 4.86 1.87 99.84
21 INT36225 Gene_expression of PYY 9 0.76 4.43 3.15 99.84
22 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 99.84
23 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.84
24 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01 99.84
25 INT12618 Positive_regulation of IAPP 54 0.68 32.03 2.29 99.84
26 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 99.84
27 INT203025 Regulation of Gene_expression of PYY 2 0.44 1.31 1.01 99.84
28 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 99.84
29 INT91337 Gene_expression of CCL4 29 0.75 16.23 8.64 99.84
30 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 99.84
31 INT20804 Regulation of Gene_expression of CCK 5 0.45 1.33 1.56 99.84
32 INT9334 Positive_regulation of Igfbp1 22 0.54 9.3 4.31 99.84
33 INT34739 Positive_regulation of Del(7)Tyr<c-23DVT>-p 17 0.35 18.86 2.54 99.84
34 INT60749 Localization of IAPP 17 0.78 12.57 1.69 99.84
35 INT178649 Regulation of Positive_regulation of Del(7)Tyr<c-23DVT>-p 1 0.02 0.9 0.06 99.84
36 INT1704 Positive_regulation of PCa 68 0.59 34.92 23.36 99.84
37 INT36262 Positive_regulation of Tbce 35 0.49 28.79 14.33 99.84
38 INT59302 Positive_regulation of POR 19 0.49 15.18 1.95 99.82
39 INT546 Binding of ALB 311 0.48 85.98 60.14 99.78
40 INT184269 Gene_expression of HMGB1 51 0.77 42.96 4.55 99.72
41 INT48726 Gene_expression of IGFBP1 27 0.67 9.45 3.36 99.72
42 INT184271 Positive_regulation of Gene_expression of HMGB1 7 0.41 6.17 1.53 99.72
43 INT93840 Gene_expression of TNNC1 15 0.57 10.07 1.54 99.70
44 INT248 Positive_regulation of Localization of GH1 137 0.69 49.25 32.92 99.68
45 INT214581 Negative_regulation of GYPC 32 0.32 21.93 3.62 99.62
46 INT186810 Positive_regulation of TLR3 13 0.65 6.37 1.37 99.60
47 INT133030 Positive_regulation of Gene_expression of TLR2 53 0.65 38.15 10.65 99.60
48 INT224407 Binding of PYY 1 0.35 0.91 1.07 99.58
49 INT182137 Gene_expression of TLR9 137 0.78 48.48 9.05 99.56
50 INT207896 Gene_expression of TLR8 3 0.36 2.82 0.26 99.56
51 INT204533 Regulation of Gene_expression of TLR9 8 0.55 2.81 0.4 99.56
52 INT334959 Regulation of Gene_expression of TLR8 1 0.21 0.91 0.05 99.56
53 INT78328 Positive_regulation of Gene_expression of CCK 5 0.70 3.84 4.38 99.50
54 INT120466 Gene_expression of LCT 21 0.78 6 1.75 99.48
55 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 99.44
56 INT12131 Gene_expression of POR 17 0.77 9.42 2.17 99.38
57 INT252 Localization of GH1 529 0.80 227.4 122.05 99.36
58 INT298738 Binding of ACSBG1 1 0.01 0.74 0 99.36
59 INT25585 Positive_regulation of DNAH8 39 0.70 17.96 7.85 99.36
60 INT4449 Positive_regulation of NA 179 0.55 40.26 37.82 99.36
61 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 99.36
62 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89 99.32
63 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 99.32
64 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.18
65 INT252991 Regulation of TAF9 2 0.44 3.54 0.08 99.16
66 INT7833 Positive_regulation of Cck 33 0.70 8.54 34.21 99.12
67 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 99.08
68 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 99.08
69 INT91217 Positive_regulation of BAG3 22 0.48 16.57 6.06 99.08
70 INT185398 Negative_regulation of Gene_expression of TLR2 34 0.55 27.21 4.73 99.04
71 INT11934 Regulation of Sv2a 4 0.44 1.72 1.1 99.04
72 INT218578 Positive_regulation of GYPC 10 0.37 5.7 1.92 98.96
73 INT220329 Positive_regulation of IAH1 3 0.20 4.37 0 98.96
74 INT103095 Binding of ISYNA1 10 0.28 6.17 2.03 98.92
75 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 98.88
76 INT61680 Positive_regulation of PVR 23 0.60 23.27 3.86 98.88
77 INT164189 Gene_expression of TREM1 82 0.62 60.77 5.85 98.80
78 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17 98.80
79 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99 98.78
80 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38 98.68
81 INT62950 Gene_expression of NPPB 73 0.75 65.91 6.54 98.64
82 INT316095 Negative_regulation of TLX1NB 1 0.23 0.68 0.19 98.64
83 INT48616 Positive_regulation of IGFBP1 14 0.43 5.62 1.56 98.52
84 INT192300 Positive_regulation of Gene_expression of IGFBP1 6 0.60 2.85 0.81 98.52
85 INT4853 Regulation of Hrh2 42 0.45 22.34 16.65 98.44
86 INT178796 Gene_expression of Itgad 1 0.75 2.05 0.24 98.44
87 INT178803 Gene_expression of Itgb2 10 0.44 5.13 0.87 98.44
88 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 98.44
89 INT298736 Positive_regulation of ACSBG1 1 0.01 1.29 0 98.40
90 INT218577 Gene_expression of GYPC 6 0.50 5.16 0.44 98.38
91 INT118607 Positive_regulation of Positive_regulation of Epo 4 0.50 3.67 0.5 98.36
92 INT28145 Binding of PAPPA 26 0.48 7.4 4.96 98.24
93 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 98.20
94 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 98.08
95 INT3098 Positive_regulation of Epo 46 0.70 28.27 7 98.06
96 INT9550 Gene_expression of TNNI3 113 0.78 86.79 10.56 98.04
97 INT115963 Negative_regulation of Gene_expression of CRH 9 0.59 4.53 1.48 98.04
98 INT6947 Negative_regulation of Gene_expression of POMC 37 0.59 10.32 14.14 98.04
99 INT203023 Regulation of PYY 4 0.44 1.09 0.84 97.96
100 INT8066 Binding of RASGRP1 10 0.36 4.65 0.58 97.96
101 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 97.92
102 INT14561 Gene_expression of Igfbp1 12 0.35 6.27 2.46 97.88
103 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 97.84
104 INT2408 Regulation of CCK 37 0.61 10.01 26.66 97.80
105 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98 97.80
106 INT4299 Positive_regulation of Gene_expression of Gh1 27 0.50 5.24 7.31 97.80
107 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 97.76
108 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 97.70
109 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 97.68
110 INT7082 Gene_expression of CRH 180 0.78 64.66 31.74 97.64
111 INT876 Localization of Gh1 843 0.80 67.75 340.82 97.56
112 INT224409 Positive_regulation of Localization of GYPC 1 0.05 0.43 0.39 97.54
113 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 97.52
114 INT49141 Gene_expression of Selp 157 0.78 85.22 24.78 97.48
115 INT179524 Negative_regulation of Pip 7 0.38 4.49 0.29 97.48
116 INT49706 Positive_regulation of TNNT2 22 0.69 12.65 1.56 97.40
117 INT49302 Localization of TNNT2 6 0.78 3.1 0.34 97.40
118 INT154455 Gene_expression of dds 4 0.58 3.84 0.46 97.40
119 INT158 Localization of Prl 2431 0.81 378.96 952.2 97.40
120 INT873 Gene_expression of Gh1 130 0.76 26.15 46.75 97.38
121 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 97.36
122 INT202198 Gene_expression of BPs 3 0.33 1.84 1.13 97.16
123 INT334064 Negative_regulation of PADI1 1 0.38 1.72 0.14 97.12
124 INT334063 Positive_regulation of Localization of PADI1 1 0.33 0.5 0 97.12
125 INT334062 Localization of PADI1 1 0.49 0.44 0 97.12
126 INT17268 Localization of PLG 9 0.78 11.71 2.06 97.12
127 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81 97.08
128 INT129971 Regulation of PVR 5 0.60 3.96 0.97 97.00
129 INT60685 Positive_regulation of Gene_expression of Epo 21 0.53 15.86 1.25 96.94
130 INT193437 Negative_regulation of MCO 4 0.48 0.68 0 96.94
131 INT224154 Positive_regulation of TREM1 14 0.56 22.65 2.71 96.80
132 INT49866 Negative_regulation of Parp1 53 0.58 35.37 8.84 96.80
133 INT49867 Negative_regulation of Polg 7 0.39 4.07 1.86 96.80
134 INT224153 Negative_regulation of Positive_regulation of TREM1 1 0.32 1.28 0.11 96.80
135 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36 96.80
136 INT47942 Positive_regulation of Glp1r 38 0.70 15.94 6.47 96.80
137 INT78182 Positive_regulation of ACCS 43 0.43 46.39 6.78 96.72
138 INT49360 Localization of Igf1 22 0.76 6.96 4.26 96.68
139 INT202200 Positive_regulation of BPs 4 0.24 1.91 1.38 96.56
140 INT5489 Localization of CA2 172 0.80 39.46 33.56 96.56
141 INT7105 Gene_expression of pad 54 0.77 63.68 8.8 96.56
142 INT96210 Positive_regulation of SLC6A2 5 0.49 1.99 2.34 96.56
143 INT98992 Binding of Vcam1 13 0.34 12.97 1.04 96.56
144 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 96.54
145 INT2843 Gene_expression of Epo 100 0.78 62.01 14.66 96.52
146 INT1029 Positive_regulation of Gene_expression of Lbp 17 0.50 11.03 5.18 96.48
147 INT186807 Positive_regulation of Gene_expression of TLR3 8 0.53 7.19 1.08 96.40
148 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33 96.40
149 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9 96.40
150 INT285448 Positive_regulation of Gene_expression of TLR7 4 0.61 2.58 0.5 96.40
151 INT219180 Gene_expression of TLR7 13 0.68 9.51 2.21 96.40
152 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 96.40
153 INT154456 Negative_regulation of dds 5 0.37 5.66 0.52 96.32
154 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 96.32
155 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38 96.20
156 INT55034 Positive_regulation of Adm 27 0.61 14.1 6.13 96.16
157 INT1027 Gene_expression of Lbp 132 0.77 106.7 54.16 96.12
158 INT55419 Regulation of CYP1A2 19 0.62 5.3 4.75 96.04
159 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 96.00
160 INT26996 Positive_regulation of Gene_expression of Crp 21 0.68 21.55 2.75 96.00
161 INT66544 Binding of Igf1 23 0.46 8.33 2.44 95.88
162 INT334958 Positive_regulation of Localization of PSMD1 1 0.10 0.87 0.1 95.88
163 INT102251 Positive_regulation of Positive_regulation of Crp 24 0.58 29.62 7.5 95.88
164 INT7365 Binding of Gh1 17 0.37 2.83 3.54 95.88
165 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 95.88
166 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 95.80
167 INT1028 Positive_regulation of Lbp 102 0.69 67.86 46.05 95.80
168 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 95.72
169 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 95.72
170 INT60440 Localization of PSMD1 10 0.74 3.94 2.57 95.60
171 INT150330 Gene_expression of BMPR2 7 0.29 4.22 0.34 95.60
172 INT189604 Negative_regulation of BMPR2 2 0.26 0.95 0.15 95.60
173 INT192082 Localization of BMPR2 1 0.32 0.55 0.15 95.60
174 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 95.36
175 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 95.36
176 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 95.36
177 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 95.36
178 INT71681 Positive_regulation of Gene_expression of CCL3 8 0.54 8.21 2.41 95.36
179 INT79234 Positive_regulation of CCL3 15 0.67 11.43 4.15 95.36
180 INT91327 Positive_regulation of CCL4 12 0.67 8.55 4.1 95.36
181 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 95.36
182 INT6480 Positive_regulation of IL1RN 59 0.69 33.7 16.66 95.36
183 INT120090 Positive_regulation of Gene_expression of CCL4 5 0.49 3.94 2.32 95.36
184 INT9993 Positive_regulation of Gene_expression of IL2 131 0.69 46.27 30.04 95.36
185 INT6474 Positive_regulation of Gene_expression of IL1RN 34 0.69 21.87 10.99 95.36
186 INT159472 Localization of NPPB 32 0.79 33.67 3.59 95.32
187 INT2039 Regulation of CYP2B6 30 0.60 7.75 6.43 95.32
188 INT238516 Regulation of Regulation of CYP2B6 1 0.05 0.73 0.27 95.32
189 INT84264 Regulation of NPPB 22 0.61 21.18 1.94 95.28
190 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 95.24
191 INT37168 Positive_regulation of APCS 22 0.67 9.61 4.59 95.20
192 INT27882 Gene_expression of HSP90B2P 52 0.75 36.51 9.59 95.12
193 INT316152 Negative_regulation of Regulation of HLA-DRA 1 0.24 1.13 0.25 95.12
194 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 95.00
195 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 94.96
196 INT234 Binding of Alb 151 0.48 52.34 32.97 94.96
197 INT15133 Regulation of HLA-DRA 19 0.34 5.84 3.9 94.92
198 INT203024 Positive_regulation of Positive_regulation of PYY 1 0.38 0.53 0.06 94.84
199 INT262317 Binding of TAF9 7 0.31 9.67 2.15 94.84
200 INT200522 Negative_regulation of Negative_regulation of PLG 2 0.41 1.53 0.24 94.80
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