D:Cryptococcal Meningitis

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Disease Term
Synonyms Cerebral Cryptococcoses, CEREBRAL CRYPTOCOCCOSES GRANULOMOUS, CEREBRAL CRYPTOCOCCOSIS, Cerebral Cryptococcosis Granulomous, Cryptococcal Meningitides, CRYPTOCOCCOSES CEREBRAL, CRYPTOCOCCOSES GRANULOMOUS CEREBRAL, Cryptococcosis Cerebral, CRYPTOCOCCOSIS GRANULOMOUS CEREBRAL, Granulomous Cerebral Cryptococcoses, GRANULOMOUS CEREBRAL CRYPTOCOCCOSIS
Documents 161
Hot Single Events 45
Hot Interactions 7

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Cryptococcal Meningitis. They are ordered first by their relevance to Cryptococcal Meningitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26 99.98
2 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26 99.98
3 INT353455 BRCA1 Positive_regulation of IL13 1 0.00 1.37 0.26 99.98
4 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36 99.98
5 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14 99.98
6 INT353453 Binding of BRCA1 and IL4 1 0.00 1.18 0.14 99.98
7 INT353452 Binding of AGRP and BRCA1 1 0.00 3.89 0.34 92.48
8 INT353450 Binding of BRCA1 and VEGFA 1 0.01 0.82 0.05 50.00
9 INT317427 IFN1@ Positive_regulation of ISYNA1 1 0.12 0.49 0.45 5.00
10 INT188746 Binding of CSF2 and HIVEP1 1 0.04 3.99 0.21 5.00
11 INT348970 Binding of MOG and HAND1 1 0.03 1.28 0.2 5.00
12 INT321957 Binding of Sar1a and Ceacam1 1 0.01 0.96 0.16 5.00
13 INT188748 AGRP Negative_regulation of CSF2 1 0.05 1.26 0.08 5.00
14 INT348971 Binding of MOG and CARTPT 1 0.06 0.73 0.08 5.00
15 INT188745 AGRP Regulation of Gene_expression of CSF2 1 0.07 1.48 0.08 5.00
16 INT317426 Binding of CSF2 and PML 1 0.08 1.25 0.06 5.00
17 INT321958 Binding of Vtn and Ceacam1 1 0.02 0.27 0 5.00
18 INT278837 Binding of ALB and KAL1 1 0.03 0.16 0 5.00
19 INT324413 Binding of MIOX and Miox 1 0.01 0 0 5.00
20 INT188747 AGRP Positive_regulation of Gene_expression of CSF2 1 0.06 1.28 0 5.00
21 INT188744 AGRP Regulation of CSF2 1 0.05 1.04 0 5.00
22 INT348972 Binding of CSF2 and MOG 1 0.21 0.41 0 5.00
23 INT188749 Binding of HIVEP1 and ADC 1 0.02 0.92 0 5.00
24 INT188750 Binding of CD4 and ADC 1 0.16 0.93 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Cryptococcal Meningitis. They are ordered first by their pain relevance and then by number of times they were reported in Cryptococcal Meningitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17 100.00
2 INT221269 Binding of BRCA1 14 0.40 31.77 2.7 99.98
3 INT259116 Transcription of BRCA1 3 0.44 3.77 0 99.98
4 INT141665 Gene_expression of AGRP 83 0.67 43.43 4.24 99.92
5 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 99.88
6 INT16404 Regulation of CD4 54 0.61 33.05 10.29 99.84
7 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 99.80
8 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 99.66
9 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 99.66
10 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22 99.66
11 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 99.48
12 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 99.48
13 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 99.48
14 INT153776 Positive_regulation of IL17A 42 0.64 34.58 14.82 99.48
15 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 99.38
16 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 99.12
17 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 99.12
18 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 99.12
19 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 99.10
20 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 98.60
21 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 98.48
22 INT166819 Gene_expression of IMPA1 12 0.65 3.85 1.77 98.28
23 INT16405 Regulation of CD8A 38 0.45 19.04 5.31 97.08
24 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 96.24
25 INT86998 Regulation of HIVEP1 49 0.44 37.83 4 96.12
26 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 94.40
27 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 93.44
28 INT10570 Positive_regulation of Cyp11a1 9 0.47 2.67 1.4 93.16
29 INT221422 Positive_regulation of BRCA1 5 0.23 12.63 1.53 92.84
30 INT271575 Gene_expression of MIOX 25 0.06 11.26 3.31 92.60
31 INT202426 Transcription of CD4 6 0.69 3.96 0.49 92.60
32 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36 92.16
33 INT353457 Positive_regulation of Binding of BRCA1 1 0.09 1.69 0.34 91.60
34 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 90.96
35 INT36287 Binding of CD4 96 0.47 58.93 11.88 88.88
36 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 87.36
37 INT6852 Localization of TNF 883 0.81 705.95 270.84 86.80
38 INT73503 Positive_regulation of Gene_expression of IL13 16 0.37 14.6 4.23 85.76
39 INT23257 Regulation of CRP 127 0.62 100.05 21.87 84.96
40 INT155010 Positive_regulation of Gene_expression of IL17A 23 0.64 20.17 7.15 84.64
41 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 83.60
42 INT73499 Positive_regulation of IL13 23 0.39 20.03 6.53 83.60
43 INT151230 Positive_regulation of IL7 14 0.37 11.89 4.56 83.60
44 INT57257 Gene_expression of IL7 69 0.62 50.24 20.36 83.16
45 INT188756 Positive_regulation of AGRP 43 0.60 23.67 2.51 80.88
46 INT108710 Gene_expression of HAL 36 0.58 14.75 2.16 78.88
47 INT221420 Positive_regulation of Gene_expression of BRCA1 2 0.24 2.17 0.55 78.80
48 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 75.52
49 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 75.00
50 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 75.00
51 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 75.00
52 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 75.00
53 INT10847 Gene_expression of LAMC2 39 0.75 27 12.09 75.00
54 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 74.24
55 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 74.16
56 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 73.60
57 INT95131 Binding of Cd4 27 0.37 21.62 5.07 73.48
58 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 70.40
59 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 70.40
60 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 68.24
61 INT102272 Regulation of TH1L 41 0.44 30.89 11.63 68.24
62 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 65.60
63 INT271571 Positive_regulation of MIOX 4 0.09 3.65 0.41 63.04
64 INT69306 Negative_regulation of TH1L 28 0.57 24.81 9.74 61.92
65 INT163613 Transcription of CSF2 16 0.60 12.98 1.62 60.80
66 INT25265 Transcription of HIVEP1 30 0.45 28.12 2.08 60.20
67 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 52.64
68 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 52.28
69 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 50.00
70 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 50.00
71 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 50.00
72 INT64473 Regulation of Gene_expression of IL4 17 0.58 6.61 3.96 50.00
73 INT14301 Binding of CSF2 82 0.48 67.95 8.98 49.12
74 INT122653 Positive_regulation of Gene_expression of CD4 48 0.68 22.5 5.96 47.12
75 INT26583 Positive_regulation of Cd4 40 0.54 21.96 4.83 46.20
76 INT77281 Negative_regulation of HIVEP1 132 0.49 102.78 5.36 44.60
77 INT188758 Negative_regulation of CPM 2 0.05 0.89 0 44.60
78 INT58477 Gene_expression of Chdh 33 0.74 39.48 19.78 44.32
79 INT22909 Positive_regulation of Chdh 26 0.68 28.69 16.13 43.84
80 INT180035 Positive_regulation of Gene_expression of Chdh 2 0.22 8.21 5.78 43.84
81 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32 41.48
82 INT177968 Negative_regulation of Transcription of CSF2 3 0.37 2.8 0.55 41.48
83 INT348975 Negative_regulation of Transcription of ALB 1 0.04 2.2 0.37 41.48
84 INT127291 Transcription of ALB 7 0.67 4.26 0.55 38.76
85 INT208149 Regulation of Positive_regulation of Cd4 1 0.06 0.93 0 31.92
86 INT228976 Binding of MCAT 3 0.06 3.45 0.17 28.04
87 INT100051 Binding of MUC5AC 20 0.32 14.21 1.14 25.68
88 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 9.68
89 INT88700 Gene_expression of CPM 8 0.76 2.55 0.56 9.68
90 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 7.48
91 INT271762 Binding of HAND1 3 0.10 3.66 0.31 7.12
92 INT245179 Localization of HAND1 1 0.19 1.09 0 7.12
93 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 7.08
94 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 5.00
95 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 5.00
96 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
97 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 5.00
98 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 5.00
99 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
100 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 5.00
101 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
102 INT88322 Gene_expression of CCR5 111 0.78 77.36 39.84 5.00
103 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 5.00
104 INT11650 Negative_regulation of Gpt 122 0.59 69.15 30.36 5.00
105 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78 5.00
106 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 5.00
107 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 5.00
108 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
109 INT36428 Binding of Chdh 42 0.47 48.04 26.54 5.00
110 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 5.00
111 INT52457 Gene_expression of ABCB1 129 0.78 38.68 19.88 5.00
112 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 5.00
113 INT89293 Positive_regulation of Gene_expression of CCR5 29 0.70 22.14 15 5.00
114 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 5.00
115 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 5.00
116 INT52905 Gene_expression of Cd4 84 0.78 45.68 12.75 5.00
117 INT6322 Gene_expression of Ceacam1 46 0.75 32.13 12.46 5.00
118 INT541 Positive_regulation of MBP 31 0.67 28.56 12.24 5.00
119 INT112003 Localization of ROS1 94 0.73 66.32 12.16 5.00
120 INT102731 Regulation of ABCB1 29 0.62 5.36 11.67 5.00
121 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 5.00
122 INT19185 Negative_regulation of Cd4 80 0.51 61.32 8.51 5.00
123 INT156396 Localization of Tg(CAG-EGFP)D4Nagy 61 0.55 13.63 8.17 5.00
124 INT764 Gene_expression of OLAH 25 0.67 25.58 8.07 5.00
125 INT18909 Positive_regulation of Cd8a 92 0.60 56.55 7.35 5.00
126 INT91758 Binding of CCR5 28 0.45 20.16 7.07 5.00
127 INT17049 Localization of CD4 57 0.75 35.33 6.89 5.00
128 INT17277 Positive_regulation of Gene_expression of HIVEP1 25 0.67 21.79 6.7 5.00
129 INT10917 Positive_regulation of ITGAM 31 0.67 16.39 6.69 5.00
130 INT22128 Positive_regulation of HIVEP1 61 0.43 70.52 6.07 5.00
131 INT117189 Binding of CXCR4 34 0.37 24.27 5.81 5.00
132 INT69944 Positive_regulation of Ndp 7 0.38 4.81 5.6 5.00
133 INT81796 Binding of AGRP 62 0.36 37.19 5.3 5.00
134 INT60252 Binding of HIVEP1 59 0.32 65.12 5.06 5.00
135 INT85301 Gene_expression of Ndp 6 0.52 4.19 4.5 5.00
136 INT15001 Localization of Gfap 29 0.75 6.71 4.1 5.00
137 INT151427 Gene_expression of ADC 31 0.55 21.86 3.81 5.00
138 INT140337 Negative_regulation of Cd8a 42 0.50 25.4 3.66 5.00
139 INT200385 Negative_regulation of ADC 19 0.18 16.56 3.6 5.00
140 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6 5.00
141 INT122448 Regulation of Gene_expression of ABCB1 13 0.62 3.67 3.5 5.00
142 INT197446 Localization of Psmd1 10 0.56 3.78 2.79 5.00
143 INT110233 Regulation of Gene_expression of CCR5 6 0.34 7.14 2.76 5.00
144 INT62487 Localization of HIVEP1 35 0.73 36.24 2.72 5.00
145 INT59454 Regulation of Gene_expression of CSF2 22 0.52 19.67 2.69 5.00
146 INT17276 Negative_regulation of Gene_expression of HIVEP1 27 0.42 26.85 2.61 5.00
147 INT122557 Localization of Chdh 6 0.74 4.44 2.6 5.00
148 INT16964 Binding of IFNG 27 0.48 14.31 2.45 5.00
149 INT55123 Binding of Ceacam1 4 0.30 4.86 2.44 5.00
150 INT200384 Regulation of ADC 12 0.25 5.46 2.41 5.00
151 INT122709 Localization of CYP3A4 16 0.75 5.41 2.38 5.00
152 INT14488 Regulation of MBP 5 0.25 5.17 2.25 5.00
153 INT17747 Regulation of Cd4 14 0.41 10.02 2.12 5.00
154 INT96588 Gene_expression of MOG 18 0.75 11.41 1.89 5.00
155 INT6321 Negative_regulation of Ceacam1 5 0.43 3.35 1.89 5.00
156 INT77523 Positive_regulation of ADC 14 0.63 13.81 1.81 5.00
157 INT12163 Positive_regulation of OLAH 8 0.68 6.91 1.67 5.00
158 INT83328 Regulation of Gene_expression of Cd4 6 0.43 2.55 1.42 5.00
159 INT74254 Binding of PTPRC 16 0.36 8.37 1.27 5.00
160 INT58692 Regulation of Gene_expression of CD8A 11 0.42 10.16 1 5.00
161 INT273038 Regulation of Vtn 3 0.08 2.26 0.91 5.00
162 INT81794 Regulation of AGRP 12 0.39 4.94 0.9 5.00
163 INT81795 Negative_regulation of AGRP 23 0.41 10.93 0.87 5.00
164 INT228088 Localization of Ceacam1 6 0.54 4.64 0.85 5.00
165 INT98567 Negative_regulation of Gene_expression of Cd4 8 0.40 6.1 0.75 5.00
166 INT179062 Positive_regulation of Positive_regulation of Cd8a 8 0.43 5.68 0.74 5.00
167 INT78329 Binding of ADC 7 0.31 7.57 0.73 5.00
168 INT196238 Binding of MOG 4 0.36 4.19 0.73 5.00
169 INT251606 Protein_catabolism of Msn 2 0.73 1.26 0.66 5.00
170 INT51336 Binding of Vtn 3 0.12 1.5 0.66 5.00
171 INT348978 Positive_regulation of MOG 6 0.49 4.2 0.63 5.00
172 INT188754 Localization of AGRP 15 0.74 8.88 0.6 5.00
173 INT321953 Protein_catabolism of Ceacam1 1 0.51 3.06 0.58 5.00
174 INT127975 Negative_regulation of SPP1 15 0.42 11.25 0.56 5.00
175 INT320849 Binding of CARTPT 5 0.14 1.85 0.54 5.00
176 INT148107 Binding of CDIPT 8 0.17 4.56 0.53 5.00
177 INT321946 Negative_regulation of Binding of Ceacam1 1 0.19 1.45 0.5 5.00
178 INT188759 Positive_regulation of Gene_expression of ADC 3 0.28 2.7 0.5 5.00
179 INT117796 Binding of CPM 5 0.48 2.79 0.45 5.00
180 INT231129 Positive_regulation of HAND1 5 0.30 2.73 0.45 5.00
181 INT340755 Negative_regulation of CARTPT 2 0.30 2.08 0.4 5.00
182 INT321955 Positive_regulation of Clta 1 0.12 1.54 0.4 5.00
183 INT321948 Regulation of Protein_catabolism of Ceacam1 1 0.20 1.65 0.38 5.00
184 INT188755 Positive_regulation of Binding of CSF2 6 0.44 8.79 0.35 5.00
185 INT228977 Binding of SERPINA2 1 0.25 5.42 0.35 5.00
186 INT287054 Regulation of Ceacam1 2 0.20 1.13 0.28 5.00
187 INT188760 Regulation of ZC3H12A 4 0.04 4.02 0.27 5.00
188 INT231128 Gene_expression of HAND1 4 0.40 1.32 0.25 5.00
189 INT321950 Transcription of Ceacam1 1 0.31 1.6 0.22 5.00
190 INT6373 Positive_regulation of AP5M1 2 0.01 1.92 0.22 5.00
191 INT248772 Negative_regulation of Binding of CSF2 4 0.39 5.16 0.19 5.00
192 INT345946 Negative_regulation of Localization of CYP3A4 1 0.09 0.56 0.16 5.00
193 INT137606 Gene_expression of Has1 5 0.77 2.05 0.14 5.00
194 INT321947 Gene_expression of Sar1a 1 0.03 0.49 0.13 5.00
195 INT188757 Positive_regulation of Gene_expression of AGRP 12 0.44 5.86 0.13 5.00
196 INT212170 Localization of CDIPT 4 0.41 1.55 0.13 5.00
197 INT178053 Positive_regulation of STIP1 7 0.44 5.09 0.11 5.00
198 INT278585 Binding of Nudc 1 0.12 1.53 0.1 5.00
199 INT321952 Protein_catabolism of Vtn 1 0.11 0.68 0.1 5.00
200 INT195608 Gene_expression of Nudc 3 0.22 3.38 0.09 5.00
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