D:Cryptococcus Infection

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Disease Term
Synonyms C Neoformans, Cryptococcoses, CRYPTOCOCCOSIS, CRYPTOCOCCUS INFECTIONS, Cryptococcus Neoformans, European Blastomycosis, T Histolytica, Torula Histolyica, TORULOSES, Torulosis
Documents 239
Hot Single Events 54
Hot Interactions 4

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Cryptococcus Infection. They are ordered first by their relevance to Cryptococcus Infection and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36 94.24
2 INT353453 Binding of BRCA1 and IL4 1 0.00 1.18 0.14 93.36
3 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14 92.88
4 INT353452 Binding of AGRP and BRCA1 1 0.00 3.89 0.34 90.64
5 INT352762 DAG1 Regulation of Sms 1 0.03 0.37 0.05 72.12
6 INT353450 Binding of BRCA1 and VEGFA 1 0.01 0.82 0.05 66.56
7 INT352758 Sms Regulation of Positive_regulation of Prkd1 1 0.14 0.63 0.08 59.44
8 INT352754 Sms Positive_regulation of Regulation of Prkd1 1 0.13 0.37 0.04 55.12
9 INT352763 Sms Regulation of Gene_expression of DAG1 1 0.08 0.64 0.11 55.04
10 INT324413 Binding of MIOX and Miox 1 0.01 0 0 50.00
11 INT203978 Binding of Srebf1 and Scap 1 0.01 0.26 0 13.92
12 INT237379 Binding of Ebi3 and Il27 2 0.05 1.71 0.82 5.00
13 INT339648 Binding of IL23A and Il23a 1 0.04 0.13 0.44 5.00
14 INT339645 Binding of Cdk5r1 and Ebi3 1 0.01 0.78 0.31 5.00
15 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26 5.00
16 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26 5.00
17 INT353455 BRCA1 Positive_regulation of IL13 1 0.00 1.37 0.26 5.00
18 INT333763 Il27 Positive_regulation of Gene_expression of Il10 2 0.22 0.8 0.26 5.00
19 INT339644 Il27 Regulation of Cd4 1 0.03 0.26 0.22 5.00
20 INT188746 Binding of CSF2 and HIVEP1 1 0.04 3.99 0.21 5.00
21 INT339647 Binding of IFN1@ and Carg1 1 0.01 0.75 0.2 5.00
22 INT174820 IL6 Positive_regulation of VEGFA 1 0.20 3.32 0.12 5.00
23 INT174821 VEGFA Positive_regulation of Gene_expression of IL6 1 0.20 3.13 0.12 5.00
24 INT352751 Pkd2 Regulation of Localization of Vegfa 1 0.11 0.47 0.1 5.00
25 INT352750 Pkd2 Positive_regulation of Vegfa 1 0.20 0.47 0.1 5.00
26 INT188748 AGRP Negative_regulation of CSF2 1 0.05 1.26 0.08 5.00
27 INT188745 AGRP Regulation of Gene_expression of CSF2 1 0.07 1.48 0.08 5.00
28 INT352766 DAG1 Positive_regulation of Prkd1 1 0.15 0.38 0.07 5.00
29 INT352755 Sms Regulation of Prkd1 1 0.22 0.34 0.07 5.00
30 INT352764 DAG1 Positive_regulation of Sms 1 0.06 0.11 0.03 5.00
31 INT199041 AGRP Regulation of IGHE 1 0.00 1.39 0.03 5.00
32 INT192678 PTEN Regulation of Dync1h1 1 0.02 0.5 0.03 5.00
33 INT352756 Hspg2 Negative_regulation of Sms 1 0.21 0.08 0 5.00
34 INT303456 Binding of USE1 and PDGFC 1 0.01 0.68 0 5.00
35 INT352753 Sgms1 Regulation of Localization of Prkd1 1 0.23 0 0 5.00
36 INT237110 Binding of CAPN7 and Iac 1 0.08 0 0 5.00
37 INT352752 Sms Positive_regulation of Localization of Prkd1 1 0.16 0.24 0 5.00
38 INT188747 AGRP Positive_regulation of Gene_expression of CSF2 1 0.06 1.28 0 5.00
39 INT188744 AGRP Regulation of CSF2 1 0.05 1.04 0 5.00
40 INT188749 Binding of HIVEP1 and ADC 1 0.02 0.92 0 5.00
41 INT237095 Binding of HMI and CAPN7 1 0.05 0.55 0 5.00
42 INT352765 DAG1 Regulation of Localization of Prkd1 1 0.09 0.09 0 5.00
43 INT188750 Binding of CD4 and ADC 1 0.16 0.93 0 5.00
44 INT352761 SGMS2 Regulation of Localization of Prkd1 1 0.20 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Cryptococcus Infection. They are ordered first by their pain relevance and then by number of times they were reported in Cryptococcus Infection. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT36287 Binding of CD4 96 0.47 58.93 11.88 99.98
2 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 99.96
3 INT94465 Positive_regulation of Gene_expression of Hand1 43 0.38 29.76 10.88 99.92
4 INT60690 Positive_regulation of Gene_expression of Il12a 69 0.63 41.41 20.85 99.76
5 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 99.48
6 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 99.48
7 INT136522 Negative_regulation of Prokr1 9 0.58 3.53 2.71 99.16
8 INT161667 Positive_regulation of Prokr1 7 0.42 2.73 1.59 99.16
9 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 99.04
10 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 98.90
11 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 98.70
12 INT103716 Gene_expression of Cms1 14 0.65 8.52 1.3 98.24
13 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 98.06
14 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25 97.52
15 INT22785 Negative_regulation of PRNP 12 0.57 5.09 1.57 97.52
16 INT202426 Transcription of CD4 6 0.69 3.96 0.49 96.44
17 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 96.04
18 INT60252 Binding of HIVEP1 59 0.32 65.12 5.06 95.72
19 INT14301 Binding of CSF2 82 0.48 67.95 8.98 95.56
20 INT16405 Regulation of CD8A 38 0.45 19.04 5.31 94.80
21 INT153776 Positive_regulation of IL17A 42 0.64 34.58 14.82 94.24
22 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 94.24
23 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 93.96
24 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 93.80
25 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 93.52
26 INT22353 Positive_regulation of Cps1 6 0.17 0.98 1.14 93.52
27 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 93.36
28 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96 93.28
29 INT174160 Binding of Il12a 19 0.24 12.61 3.4 93.24
30 INT221269 Binding of BRCA1 14 0.40 31.77 2.7 93.00
31 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 92.88
32 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 92.88
33 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 92.88
34 INT42707 Gene_expression of Tbce 24 0.65 12.92 7.93 92.24
35 INT138872 Gene_expression of SPINK5 21 0.58 30.11 4.12 92.08
36 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17 91.84
37 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 91.20
38 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 91.20
39 INT155010 Positive_regulation of Gene_expression of IL17A 23 0.64 20.17 7.15 91.04
40 INT352710 Negative_regulation of Sms 1 0.25 2.53 0.22 90.24
41 INT352725 Negative_regulation of Sgms1 1 0.41 0.64 0.12 90.24
42 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 88.96
43 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78 88.56
44 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 88.28
45 INT100939 Gene_expression of Il13 176 0.73 125.1 43.38 88.20
46 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 88.20
47 INT33008 Gene_expression of Dync1h1 41 0.68 23.85 3.82 86.92
48 INT203956 Positive_regulation of Protein_catabolism of Srebf1 1 0.03 0.96 0 86.36
49 INT198867 Protein_catabolism of Srebf1 2 0.08 1.2 0 86.36
50 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 86.28
51 INT188756 Positive_regulation of AGRP 43 0.60 23.67 2.51 85.92
52 INT286550 Negative_regulation of Prkd1 4 0.42 3.68 0.45 82.52
53 INT80007 Transcription of GRIN1 5 0.67 2.36 3.26 81.44
54 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 80.92
55 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 78.60
56 INT25797 Positive_regulation of OR2AL1P 5 0.09 5.14 0.99 78.60
57 INT141665 Gene_expression of AGRP 83 0.67 43.43 4.24 78.48
58 INT189771 Gene_expression of DAG1 5 0.27 4.14 1.12 77.68
59 INT63607 Positive_regulation of Pbrgcsf1 11 0.42 5.48 2.81 77.64
60 INT150022 Positive_regulation of Il17a 69 0.64 70.04 21.87 77.64
61 INT161515 Positive_regulation of Gene_expression of Il17a 50 0.64 41.52 13.82 77.64
62 INT15007 Gene_expression of Pbrgcsf1 31 0.49 17.82 6.99 77.24
63 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 77.24
64 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 77.04
65 INT141275 Negative_regulation of Gene_expression of Hand1 18 0.34 15.83 5.05 75.00
66 INT93045 Negative_regulation of Gene_expression of Hand2 31 0.43 25.26 9.24 75.00
67 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 75.00
68 INT10016 Negative_regulation of CD8A 81 0.42 56.68 13.15 75.00
69 INT725 Negative_regulation of IgG 62 0.41 37.21 8.16 75.00
70 INT1922 Positive_regulation of CEACAM7 32 0.70 33.31 2.72 74.20
71 INT203955 Binding of Srebf1 6 0.31 1.85 0.12 73.92
72 INT12163 Positive_regulation of OLAH 8 0.68 6.91 1.67 73.36
73 INT208430 Gene_expression of Sms 2 0.45 2.02 0.23 73.12
74 INT12324 Positive_regulation of PRTN3 26 0.70 18.82 4.55 71.60
75 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57 71.00
76 INT764 Gene_expression of OLAH 25 0.67 25.58 8.07 70.64
77 INT133172 Gene_expression of Il12b 98 0.75 52.16 10.68 70.40
78 INT133170 Negative_regulation of Il12b 12 0.05 5.32 1.86 70.08
79 INT64473 Regulation of Gene_expression of IL4 17 0.58 6.61 3.96 70.04
80 INT354843 Protein_catabolism of CR1 1 0.22 1.67 0 69.88
81 INT354842 Protein_catabolism of CLU 1 0.28 1.6 0 68.96
82 INT38987 Protein_catabolism of INS 21 0.99 11.92 2.91 68.52
83 INT221422 Positive_regulation of BRCA1 5 0.23 12.63 1.53 66.56
84 INT20394 Binding of Tbce 12 0.06 5.47 1.78 64.92
85 INT18909 Positive_regulation of Cd8a 92 0.60 56.55 7.35 62.80
86 INT135411 Gene_expression of Il23a 76 0.72 72.87 26.15 62.36
87 INT87468 Negative_regulation of Mmp2 24 0.57 10.79 5.55 61.08
88 INT67855 Negative_regulation of PPIG 64 0.57 17.83 13.54 59.52
89 INT286548 Positive_regulation of Prkd1 7 0.36 4.35 0.15 59.44
90 INT284325 Positive_regulation of Gene_expression of DAG1 3 0.13 1.08 0.36 57.44
91 INT286535 Regulation of Prkd1 3 0.33 2.24 0.04 54.32
92 INT35254 Negative_regulation of SERPINB1 22 0.48 11.42 4.7 52.64
93 INT37193 Negative_regulation of BDNF-AS 21 0.37 15.06 3.12 52.64
94 INT247403 Negative_regulation of Gene_expression of SERPINB1 1 0.01 0.77 0 52.64
95 INT16068 Gene_expression of SERPINB1 27 0.60 20.51 6.56 52.00
96 INT10721 Gene_expression of BDNF-AS 119 0.76 72.8 16.29 52.00
97 INT183753 Regulation of HBM 24 0.39 13.13 1.79 50.16
98 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 50.00
99 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 50.00
100 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 50.00
101 INT10870 Regulation of IgG 67 0.59 43.27 12.74 50.00
102 INT20205 Binding of IgG 108 0.46 66.68 8.57 50.00
103 INT60700 Gene_expression of Itgax 93 0.71 51.89 6.57 50.00
104 INT84572 Gene_expression of Zmat3 67 0.07 37.61 5.86 50.00
105 INT15173 Positive_regulation of Gene_expression of Itgam 59 0.49 21.89 5.43 50.00
106 INT35683 Gene_expression of Gsr 24 0.46 16.94 3.6 50.00
107 INT271575 Gene_expression of MIOX 25 0.06 11.26 3.31 50.00
108 INT171117 Binding of Itgam 35 0.36 14.87 2.76 50.00
109 INT58432 Positive_regulation of Gsr 12 0.70 9.4 1.94 50.00
110 INT166819 Gene_expression of IMPA1 12 0.65 3.85 1.77 50.00
111 INT128478 Positive_regulation of Ptprc 26 0.44 8.1 1.45 50.00
112 INT87329 Positive_regulation of Gene_expression of Itgax 15 0.64 10.85 0.93 50.00
113 INT113891 Binding of Gsr 5 0.21 4.86 0.42 50.00
114 INT271571 Positive_regulation of MIOX 4 0.09 3.65 0.41 50.00
115 INT115707 Negative_regulation of CYP51A1 2 0.40 0.67 0.15 50.00
116 INT274208 Positive_regulation of Gene_expression of Gsr 3 0.14 2.15 0.13 50.00
117 INT271580 Binding of MIOX 2 0.04 0.68 0.07 50.00
118 INT212916 Positive_regulation of Binding of 5 0.24 1.74 0.04 50.00
119 INT324394 Positive_regulation of Miox 2 0.06 0.36 0.03 50.00
120 INT324411 Localization of MIOX 1 0.07 0 0 50.00
121 INT324410 Regulation of Binding of MIOX 1 0.05 0.17 0 50.00
122 INT324395 Gene_expression of Ir2 1 0.65 0.19 0 50.00
123 INT324393 Binding of Miox 1 0.04 0 0 50.00
124 INT324412 Negative_regulation of Localization of MIOX 1 0.04 0 0 50.00
125 INT324396 Negative_regulation of Miox 1 0.05 0 0 50.00
126 INT60500 Negative_regulation of Tbce 21 0.41 13.3 11.1 49.48
127 INT14690 Localization of CSF2 124 0.80 85.17 27.26 48.32
128 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 46.12
129 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 45.00
130 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 44.68
131 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 42.88
132 INT17277 Positive_regulation of Gene_expression of HIVEP1 25 0.67 21.79 6.7 42.88
133 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 41.88
134 INT197156 Binding of CAPN7 2 0.27 1.89 0 40.44
135 INT168263 Gene_expression of IL23A 57 0.58 47.1 17.67 37.20
136 INT203951 Regulation of Mbtps2 1 0.01 0.27 0 32.80
137 INT237106 Regulation of Binding of CAPN7 1 0.33 0.46 0 32.68
138 INT237102 Regulation of CAPN7 1 0.45 0.82 0 32.12
139 INT208431 Positive_regulation of Sms 2 0.34 2.1 0.23 30.76
140 INT177831 Gene_expression of HDAC1 24 0.65 21.37 8.37 29.04
141 INT268770 Positive_regulation of am 1 0.02 0.59 0.03 28.72
142 INT158764 Binding of SPINK5 7 0.35 8.84 0.37 28.36
143 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 25.00
144 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 25.00
145 INT91703 Negative_regulation of Myoz1 78 0.58 53.78 13.5 25.00
146 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 25.00
147 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36 25.00
148 INT203950 Regulation of Mbtps1 1 0.01 0.21 0 24.32
149 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11 23.92
150 INT214942 Gene_expression of Anxa6 2 0.04 0.19 0 23.52
151 INT203952 Regulation of Scap 1 0.19 0.69 0 22.96
152 INT268769 Gene_expression of am 1 0.02 0.19 0 22.68
153 INT65642 Binding of Dync1h1 27 0.41 15.83 2.68 22.64
154 INT1631 Binding of Hdl1 42 0.36 49.22 2.92 22.00
155 INT81794 Regulation of AGRP 12 0.39 4.94 0.9 22.00
156 INT203949 Regulation of Srebf1 8 0.38 3.19 0.48 21.20
157 INT24231 Localization of SERPINB1 13 0.61 3.1 3.61 20.68
158 INT21604 Localization of BDNF-AS 12 0.73 9.5 0.79 20.68
159 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 20.00
160 INT57785 Positive_regulation of SGCB 25 0.69 5.01 1.49 19.52
161 INT192676 Binding of PTEN 14 0.46 10.58 3.06 15.76
162 INT16404 Regulation of CD4 54 0.61 33.05 10.29 14.84
163 INT239025 Regulation of Gene_expression of Il17a 9 0.42 7.18 2.09 14.68
164 INT88949 Positive_regulation of Il12a 79 0.60 47.68 19.98 14.08
165 INT127975 Negative_regulation of SPP1 15 0.42 11.25 0.56 6.64
166 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
167 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 5.00
168 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
169 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
170 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
171 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
172 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 5.00
173 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 5.00
174 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
175 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
176 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
177 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
178 INT10166 Localization of Tnf 237 0.81 153.95 88.64 5.00
179 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 5.00
180 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 5.00
181 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
182 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
183 INT6849 Localization of IL1B 229 0.81 112.56 69.63 5.00
184 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
185 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 5.00
186 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 5.00
187 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
188 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 5.00
189 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 5.00
190 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
191 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22 5.00
192 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 5.00
193 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 5.00
194 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 5.00
195 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43 5.00
196 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 5.00
197 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17 5.00
198 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 5.00
199 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24 5.00
200 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 5.00
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