D:Cumulative Trauma Disorders

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pChart

Disease Term
Synonyms Cumulative Trauma Disorder, Disorder Cumulative Trauma, Disorder Repetitive Motion, DISORDERS CUMULATIVE TRAUMA, Disorders Repetitive Motion, Injuries Overuse, Injuries Repetition Strain, Injuries Repetitive Strain, Injury Overuse, Injury Repetition Strain, INJURY REPETITIVE STRAIN
Documents 502
Hot Single Events 16
Hot Interactions 4

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Cumulative Trauma Disorders. They are ordered first by their relevance to Cumulative Trauma Disorders and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14 99.04
2 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24 98.24
3 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28 97.36
4 INT198729 Binding of Exa and Femwf1 1 0.05 0.37 0 80.80
5 INT198727 Exa Regulation of Femwf1 1 0.06 0.07 0 70.20
6 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03 53.48
7 INT108387 IL1B Positive_regulation of Localization of MMP1 1 0.27 0.3 0.57 37.84
8 INT198730 Femwf1 Positive_regulation of Exa 1 0.06 0 0 6.84
9 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1 5.00
10 INT238270 Binding of VMO1 and MSLNL 1 0.11 0.42 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Cumulative Trauma Disorders. They are ordered first by their pain relevance and then by number of times they were reported in Cumulative Trauma Disorders. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT110777 Regulation of CTD 4 0.23 3.17 0.42 100.00
2 INT114157 Positive_regulation of CTD 7 0.24 6.94 1.82 100.00
3 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.04
4 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 98.48
5 INT108394 Positive_regulation of ADAMTS4 5 0.49 1.65 1.78 98.24
6 INT93663 Positive_regulation of MMP1 72 0.67 33.38 19.86 97.36
7 INT38561 Regulation of SEMG1 19 0.51 3.75 3.66 93.20
8 INT111890 Binding of MSD 26 0.41 8.05 1.71 92.32
9 INT213623 Localization of Btrc 1 0.59 0.36 0.09 89.08
10 INT213622 Positive_regulation of Btrc 1 0.36 0.36 0.09 89.08
11 INT198717 Positive_regulation of Exa 1 0.22 1.42 0.41 87.44
12 INT63536 Gene_expression of Syncrip 7 0.67 7.23 5.44 84.72
13 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 84.16
14 INT198724 Phosphorylation of Exa 1 0.20 0.35 0 84.00
15 INT91527 Gene_expression of CTSK 38 0.78 22.21 7.42 83.12
16 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 82.44
17 INT60066 Positive_regulation of NPEPPS 17 0.22 11.99 4.83 79.08
18 INT102989 Regulation of Gene_expression of MMP3 10 0.53 3.29 1.47 78.88
19 INT26314 Positive_regulation of MMP3 48 0.67 22.14 16.17 78.88
20 INT123779 Positive_regulation of MMP13 42 0.65 24.3 12.45 78.88
21 INT129962 Positive_regulation of Gene_expression of MMP13 41 0.65 20.74 8.54 78.88
22 INT102237 Positive_regulation of Gene_expression of MMP3 22 0.44 7.77 4.71 78.88
23 INT151309 Positive_regulation of Positive_regulation of MMP3 5 0.60 2.62 2.5 78.88
24 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78 78.24
25 INT264009 Regulation of Syncrip 3 0.47 2.49 1.27 78.08
26 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98 77.88
27 INT198722 Gene_expression of Femwf1 1 0.25 0.65 0.13 74.24
28 INT198725 Gene_expression of Exa 1 0.22 0.25 0.05 74.24
29 INT19763 Gene_expression of CTs 69 0.78 32.92 18.87 72.92
30 INT198719 Regulation of Exa 1 0.20 0.49 0 72.84
31 INT139528 Regulation of Femwf1 2 0.23 0.44 0 72.84
32 INT10357 Binding of Syncrip 8 0.37 8.95 8.07 70.64
33 INT99157 Binding of SIL1 8 0.35 2.66 2.33 69.80
34 INT21582 Regulation of Gene_expression of TIMP1 20 0.61 12.39 4.77 64.44
35 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 64.16
36 INT141151 Regulation of PSMD1 16 0.40 8.19 5.86 61.88
37 INT70067 Regulation of KNCN 2 0.07 1.71 1.17 61.88
38 INT214530 Positive_regulation of Mup1 7 0.58 5.5 3.74 61.20
39 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86 57.68
40 INT156348 Regulation of Mup1 10 0.52 6.79 4.6 56.60
41 INT1026 Binding of Lbp 207 0.48 150.96 119.16 54.20
42 INT15610 Localization of GOPC 223 0.65 68.26 28.7 50.00
43 INT28493 Positive_regulation of IL1RL1 10 0.47 3.44 1.11 50.00
44 INT127591 Binding of Ceacam1 7 0.35 2.18 0.79 43.36
45 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79 40.64
46 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 39.08
47 INT108393 Positive_regulation of Localization of MMP1 5 0.40 0.85 1.91 37.24
48 INT103210 Localization of MMP1 43 0.78 12.15 15.13 36.80
49 INT5793 Binding of CTS 110 0.48 63.91 40.62 36.04
50 INT9500 Negative_regulation of Ceacam1 26 0.58 6.89 3.91 33.36
51 INT6849 Localization of IL1B 229 0.81 112.56 69.63 30.72
52 INT1030 Localization of Lbp 52 0.74 38.92 24.91 22.72
53 INT297116 Regulation of Gene_expression of Pain1 2 0.02 5.71 5.71 22.48
54 INT77855 Gene_expression of Pain1 55 0.75 67.42 54.1 22.08
55 INT198723 Negative_regulation of Binding of Femwf1 1 0.16 0.06 0 22.04
56 INT198720 Binding of Femwf1 5 0.26 0.21 0 21.52
57 INT198721 Binding of Exa 1 0.12 0.06 0 17.60
58 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
59 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 5.00
60 INT9664 Binding of LBP 127 0.48 94.9 63.42 5.00
61 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 5.00
62 INT1027 Gene_expression of Lbp 132 0.77 106.7 54.16 5.00
63 INT1028 Positive_regulation of Lbp 102 0.69 67.86 46.05 5.00
64 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 5.00
65 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54 5.00
66 INT48235 Negative_regulation of NPEPPS 72 0.46 44.54 25.03 5.00
67 INT24569 Negative_regulation of Pain1 26 0.41 21.82 21.08 5.00
68 INT28151 Positive_regulation of CTs 55 0.61 35.09 20.14 5.00
69 INT178828 Regulation of Pain1 12 0.14 16.1 15.64 5.00
70 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
71 INT5333 Gene_expression of NPEPPS 45 0.65 26.34 15.25 5.00
72 INT1168 Binding of PROC 62 0.38 44.15 9.04 5.00
73 INT21579 Negative_regulation of Gene_expression of TIMP1 25 0.57 12.41 6.94 5.00
74 INT22781 Binding of COL7A1 76 0.48 41.59 6.66 5.00
75 INT57274 Positive_regulation of Gene_expression of COL7A1 50 0.69 24.19 4.72 5.00
76 INT5332 Negative_regulation of Gene_expression of NPEPPS 11 0.04 7.79 4.29 5.00
77 INT264010 Localization of Syncrip 2 0.65 3.06 3.19 5.00
78 INT196710 Positive_regulation of VMO1 9 0.64 3.49 3.08 5.00
79 INT234111 Gene_expression of NCS1 3 0.74 15.23 2.68 5.00
80 INT145970 Negative_regulation of MSD 11 0.50 4.7 2.26 5.00
81 INT233102 Regulation of VMO1 4 0.34 2.7 2.25 5.00
82 INT175084 Gene_expression of Mup1 11 0.61 3.58 1.81 5.00
83 INT183276 Negative_regulation of Adrm1 10 0.04 7.25 1.74 5.00
84 INT297117 Gene_expression of TSSK1B 1 0.65 1.59 1.69 5.00
85 INT171997 Gene_expression of ERAL1 5 0.25 4.97 1.67 5.00
86 INT264008 Positive_regulation of Syncrip 2 0.50 1.71 1.63 5.00
87 INT79141 Regulation of Gene_expression of NPEPPS 3 0.01 2.95 1.61 5.00
88 INT28647 Binding of CTD 13 0.31 14.2 1.5 5.00
89 INT196714 Binding of VMO1 4 0.30 1.51 1.46 5.00
90 INT232492 Gene_expression of MROS 5 0.57 4.13 1.02 5.00
91 INT266556 Positive_regulation of AMH 9 0.70 4.33 0.82 5.00
92 INT238271 Binding of WSN 2 0.04 2.61 0.81 5.00
93 INT196713 Gene_expression of VMO1 2 0.54 1.11 0.59 5.00
94 INT106169 Localization of RHOJ 3 0.78 1.73 0.56 5.00
95 INT214540 Negative_regulation of Mup1 5 0.34 1.51 0.34 5.00
96 INT304579 Positive_regulation of Gene_expression of Mup1 1 0.23 0.33 0.27 5.00
97 INT264011 Negative_regulation of Gene_expression of Mup1 1 0.22 0.75 0.25 5.00
98 INT330744 Binding of RRIS 1 0.30 1.07 0.23 5.00
99 INT104065 Negative_regulation of Btrc 3 0.38 1.4 0.19 5.00
100 INT5113 Binding of MROS 4 0.31 2.52 0.17 5.00
101 INT251821 Negative_regulation of COL11A1 3 0.42 3.45 0.16 5.00
102 INT261721 Negative_regulation of Stl2 1 0.07 1.38 0.16 5.00
103 INT294882 Transcription of MROS 1 0.42 0.18 0.04 5.00
104 INT266557 Gene_expression of LEO1 1 0.05 0.37 0.03 5.00
105 INT330743 Negative_regulation of RRIS 1 0.47 2.29 0 5.00
106 INT330742 Localization of RRIS 1 0.60 1.17 0 5.00
107 INT317587 Negative_regulation of Negative_regulation of Adrm1 1 0.03 0 0 5.00
108 INT330741 Positive_regulation of RRIS 1 0.37 0.63 0 5.00
109 INT198718 Localization of Exa 1 0.24 0.19 0 5.00
110 INT198726 Regulation of Binding of Exa 1 0.15 0 0 5.00
111 INT317588 Regulation of Adrm1 1 0.05 0 0 5.00
112 INT266558 Binding of AMH 2 0.08 0.47 0 5.00
113 INT198716 Negative_regulation of Localization of Exa 1 0.14 0.19 0 5.00
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