D:Cv General 2 Under Development

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pChart

Disease Term
Synonyms A V Block, Adams Stokes Attacks, Adams Stokes Seizures, Agranulocytic Angina, Angina Agranulocytic, Atrial Septal Defect, Atrioventricular Block, Atrioventricular Dissociation, Atrioventricular Dysfunction, AV BLOCK, AV BLOCK COMPLETE
Documents 2815
Hot Single Events 200
Hot Interactions 14

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Cv General 2 Under Development. They are ordered first by their relevance to Cv General 2 Under Development and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT174959 Binding of IL6 and Positive_regulation of Transcription of HSP90B2P 1 0.02 0.9 0 100.00
2 INT265383 Hsp90aa1 Negative_regulation of HDAC9 1 0.06 0.7 0 100.00
3 INT239402 Binding of NPPA and ASAP1 1 0.19 1.24 0.04 98.88
4 INT239401 FIG4 Regulation of NPPA 1 0.17 2.24 0 98.52
5 INT265646 Binding of Mapk1 and Mapk14 1 0.01 1.53 0.46 94.92
6 INT265647 Binding of Ephb1 and Mapk1 1 0.00 1.48 0.43 94.92
7 INT320695 TNF Positive_regulation of Localization of Il1 1 0.05 1.38 0.44 93.52
8 INT250780 IRF6 Positive_regulation of ASAP1 1 0.06 0.34 0.04 90.64
9 INT181645 Edn1 Positive_regulation of NOS3 1 0.02 0.21 0.07 90.16
10 INT290708 Binding of Tlr4 and Cd200r1 Positive_regulation of Positive_regulation of Nos2 1 0.01 0.78 0.27 89.60
11 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73 86.88
12 INT287794 Binding of IGHG3 and AIP 1 0.05 2.8 0.24 86.20
13 INT290707 Binding of Tlr4 and Cd200r1 1 0.01 0.7 0.26 83.04
14 INT209581 Twist1 Positive_regulation of Gene_expression of VEGFA 6 0.06 7.86 0.16 81.56
15 INT241780 Binding of AVP and TRGV9 1 0.12 2.41 0.35 76.00
16 INT279242 Negative_regulation of Binding of GLA and SH3GL3 1 0.08 1.22 0 75.92
17 INT279240 Binding of GLA and SH3GL3 1 0.07 1.21 0 75.04
18 INT144862 Tlr4 Positive_regulation of PGE 2 0.13 0.35 0.28 75.00
19 INT144861 Regulation of Tlr4 Positive_regulation of PGE 1 0.01 0.13 0.17 75.00
20 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34 71.52
21 INT84622 Binding of RERE and KAL1 1 0.00 1.18 0.07 71.44
22 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73 71.12
23 INT195777 THBD Positive_regulation of PROC 1 0.00 1.26 0.08 67.60
24 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58 60.64
25 INT320694 C5 Regulation of Gene_expression of Il2 1 0.03 2.15 0.34 60.08
26 INT320692 C5 Regulation of Gene_expression of Il12a 1 0.03 2.15 0.34 60.08
27 INT320693 C5 Regulation of Gene_expression of Il6 1 0.04 2.15 0.34 60.08
28 INT320696 C5 Regulation of Gene_expression of TNF 1 0.34 2.15 0.34 60.08
29 INT320691 C5 Regulation of Gene_expression of Il1 1 0.06 2.15 0.34 60.08
30 INT260807 Binding of Chkb and Tnfsf10 1 0.14 0.85 0 58.40
31 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03 54.80
32 INT61824 Binding of SERPINH1 and CRP 1 0.24 0.63 0.08 38.32
33 INT105267 Negative_regulation of VEGFA Positive_regulation of KDR 1 0.16 0.22 0.05 38.24
34 INT105268 VEGFA Positive_regulation of KDR 2 0.18 0.22 0.05 38.24
35 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15 36.28
36 INT292749 Akt1 Positive_regulation of Ctnnd2 1 0.09 1.73 0.15 36.28
37 INT292748 Akt1 Negative_regulation of Positive_regulation of Casp3 1 0.01 1.81 0.15 36.28
38 INT203009 Binding of Cpb1 and Dob2 1 0.02 0.77 0 32.88
39 INT230723 ERVW-1 Positive_regulation of Gene_expression of EDN1 1 0.00 1.95 0 31.92
40 INT195823 Binding of Alb and Ptger2 1 0.03 1.46 0 31.36
41 INT195837 Tlr4 Positive_regulation of Pla2g4a 1 0.01 0.44 0.03 25.84
42 INT195836 Tlr4 Regulation of Gene_expression of Ptges 1 0.00 0.52 0.03 25.84
43 INT195835 Tlr4 Regulation of Ptges 1 0.00 0.52 0.03 25.84
44 INT241777 Negative_regulation of Binding of AVP and TRGV9 1 0.10 0.75 0.13 19.20
45 INT314134 Negative_regulation of Nos2 Positive_regulation of Ucp3 1 0.36 0.45 0.05 12.72
46 INT314135 Negative_regulation of Nos2 Positive_regulation of Lep 1 0.52 0.44 0.05 12.72
47 INT234802 Binding of AQP2 and AVPR2 2 0.15 0.84 0.07 11.04
48 INT181617 IL17A Positive_regulation of ISYNA1 1 0.01 0.27 0.2 9.36
49 INT181646 interleukin-17 Positive_regulation of ISYNA1 1 0.01 0.26 0.2 8.80
50 INT342910 LPA Negative_regulation of PLG 1 0.15 0.44 0 8.76
51 INT292621 Binding of IL6 and Gpt 1 0.01 3.88 0.24 8.48
52 INT179232 Binding of CREM and GSR 1 0.00 0 0.06 6.84
53 INT352482 Binding of PCA and Uncx 1 0.00 0.06 0 6.44
54 INT179230 Binding of MAPK14 and GSR 1 0.03 0.5 0.23 6.40
55 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
56 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
57 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 5.00
58 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01 5.00
59 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 5.00
60 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 5.00
61 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68 5.00
62 INT194863 Binding of IL1R1 and IL1RN 5 0.09 2.23 1.64 5.00
63 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55 5.00
64 INT208991 Binding of CALM1 and Ca2 10 0.06 1.34 1.55 5.00
65 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54 5.00
66 INT229094 Binding of IL1RN and Il1r1 1 0.01 1.9 1.5 5.00
67 INT264988 Binding of CYP2C19 and CYP3A4 1 0.18 0.72 1.09 5.00
68 INT264987 Binding of CYP2C9 and CYP3A4 1 0.19 0.71 1.08 5.00
69 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 5.00
70 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
71 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99 5.00
72 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98 5.00
73 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83 5.00
74 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79 5.00
75 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77 5.00
76 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7 5.00
77 INT229085 IL1RN Negative_regulation of Positive_regulation of IL1R1 1 0.12 1.72 0.68 5.00
78 INT205702 P2rx7 Regulation of Gene_expression of Il1 1 0.04 1.38 0.67 5.00
79 INT99728 Binding of F13A1 and PLG 4 0.02 2.51 0.63 5.00
80 INT45780 GNRH1 Positive_regulation of PLOD1 3 0.07 1.02 0.63 5.00
81 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61 5.00
82 INT276598 Il10 Positive_regulation of Gene_expression of Paf 1 0.29 0.49 0.6 5.00
83 INT276597 Paf Positive_regulation of Il10 1 0.27 0.48 0.6 5.00
84 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6 5.00
85 INT276603 Il10 Positive_regulation of Gene_expression of Tlr4 1 0.12 0.49 0.6 5.00
86 INT352496 AVP Regulation of Gene_expression of CRS 1 0.27 2.47 0.59 5.00
87 INT308803 Binding of Pld1 and Pld2 1 0.13 1.11 0.59 5.00
88 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58 5.00
89 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58 5.00
90 INT212813 Tlr4 Positive_regulation of Nos2 3 0.34 0.89 0.57 5.00
91 INT179503 Cd14 Regulation of Positive_regulation of Tlr4 1 0.38 0.58 0.52 5.00
92 INT106744 Binding of CRP and EGFL7 2 0.07 2.35 0.51 5.00
93 INT229095 Binding of IL1R1 and Il1r1 1 0.00 0.64 0.5 5.00
94 INT179507 Tlr4 Positive_regulation of Tlr2 2 0.17 1.07 0.49 5.00
95 INT179237 Binding of SERPINA6 and POMC 1 0.03 1.15 0.49 5.00
96 INT292873 Binding of Fas and Fasl 5 0.26 15.74 0.49 5.00
97 INT231732 Negative_regulation of Binding of Tnfrsf11a and Tnfsf11 1 0.01 1.03 0.48 5.00
98 INT231733 Binding of Tnfrsf11a and Tnfsf11 1 0.01 1.03 0.48 5.00
99 INT132792 IL4 Positive_regulation of IL6 4 0.28 1.81 0.47 5.00
100 INT180958 Binding of F13A1 and PLAT 2 0.03 2.16 0.47 5.00
101 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46 5.00
102 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46 5.00
103 INT246938 Binding of Tlr4 and Tlr2 3 0.39 2.88 0.46 5.00
104 INT222283 Negative_regulation of Casp1 Negative_regulation of Il1a 1 0.00 0.78 0.46 5.00
105 INT234599 Cpox Negative_regulation of Gene_expression of Ptgds 1 0.05 0.6 0.44 5.00
106 INT234600 Negative_regulation of Cpox Negative_regulation of Gene_expression of Ptgds 1 0.05 0.6 0.44 5.00
107 INT352972 IL4 Negative_regulation of Gene_expression of IL8 1 0.07 1.01 0.43 5.00
108 INT352986 IL10 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.43 5.00
109 INT352985 IL4 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.43 5.00
110 INT156438 Cpox Positive_regulation of Nos2 3 0.14 1.24 0.4 5.00
111 INT352970 IL4 Negative_regulation of Positive_regulation of TH1L 1 0.01 0.91 0.4 5.00
112 INT234608 Socs3 Negative_regulation of SOAT1 1 0.01 0.54 0.39 5.00
113 INT234607 Socs3 Negative_regulation of JAK1 1 0.01 0.54 0.39 5.00
114 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39 5.00
115 INT198652 F2 Positive_regulation of Gene_expression of CD36 1 0.03 1.32 0.37 5.00
116 INT250781 IRF6 Positive_regulation of AMIGO2 1 0.02 1.25 0.35 5.00
117 INT174699 Binding of Tlr2 and Tlr3 3 0.14 0.66 0.35 5.00
118 INT205704 P2rx7 Regulation of Localization of Il18 1 0.09 0.67 0.35 5.00
119 INT198647 TNF Positive_regulation of HIF1A 1 0.03 2.97 0.34 5.00
120 INT172004 IL17A Positive_regulation of Gene_expression of IL6 2 0.14 1.35 0.34 5.00
121 INT182126 IRF6 Positive_regulation of Gene_expression of SELE 1 0.03 0.86 0.34 5.00
122 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 0.03 0.77 0.33 5.00
123 INT229087 IL1R1 Negative_regulation of ACCS 1 0.03 0.86 0.33 5.00
124 INT198642 GPI Positive_regulation of TNF 1 0.03 0.98 0.33 5.00
125 INT205703 P2rx7 Regulation of Positive_regulation of Casp1 1 0.11 0.66 0.33 5.00
126 INT205711 P2rx7 Regulation of Localization of IL8 1 0.02 0.92 0.33 5.00
127 INT241776 Binding of AVP and Positive_regulation of ADCY1 1 0.06 0.54 0.32 5.00
128 INT276604 Tlr4 Positive_regulation of Gene_expression of Paf 1 0.22 0.37 0.31 5.00
129 INT276605 Tlr4 Positive_regulation of Gene_expression of Mthfd1 1 0.06 0.37 0.31 5.00
130 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
131 INT276602 Paf Positive_regulation of Gene_expression of Mthfd1 1 0.13 0.37 0.31 5.00
132 INT198640 TNF Positive_regulation of ISYNA1 1 0.04 1.07 0.29 5.00
133 INT319753 Mpo Positive_regulation of Timp1 1 0.14 2.13 0.29 5.00
134 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28 5.00
135 INT329369 Jun Regulation of Gene_expression of Il12a 1 0.00 1.48 0.27 5.00
136 INT132801 IL4 Positive_regulation of Localization of IL6 2 0.26 1.47 0.26 5.00
137 INT198648 VCAM1 Positive_regulation of CADM1 1 0.00 1.1 0.25 5.00
138 INT179233 IRF6 Negative_regulation of Binding of GSR 1 0.03 0.83 0.25 5.00
139 INT205701 P2rx7 Positive_regulation of Il1 1 0.04 0.8 0.25 5.00
140 INT198644 TNF Positive_regulation of CADM1 1 0.02 1.07 0.24 5.00
141 INT198643 CD36 Positive_regulation of CADM1 1 0.01 1.07 0.24 5.00
142 INT231206 Binding of KCNH2 and KCNQ1 2 0.22 1.04 0.24 5.00
143 INT329368 Ccl2 Negative_regulation of Jun 1 0.01 1.87 0.24 5.00
144 INT308805 Positive_regulation of Pld1 Positive_regulation of TNF 1 0.05 0.74 0.24 5.00
145 INT179229 Binding of GSR and NR3C2 1 0.03 0.37 0.23 5.00
146 INT250783 APC Negative_regulation of SERPINE1 1 0.06 0.86 0.23 5.00
147 INT250782 APC Negative_regulation of F2 1 0.00 0.86 0.23 5.00
148 INT279503 Binding of C1s and C1ra 1 0.03 0.58 0.22 5.00
149 INT318174 Binding of Crp and Xcl1 1 0.03 1.9 0.22 5.00
150 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 5.00
151 INT355503 Positive_regulation of SCN10A Positive_regulation of Localization of NPY 1 0.17 1.32 0.22 5.00
152 INT250779 PROC Regulation of IRF6 Positive_regulation of AMIGO2 1 0.00 0.74 0.22 5.00
153 INT306178 Rhoa Positive_regulation of Rock2 2 0.40 1.04 0.21 5.00
154 INT241822 Binding of CD4 and HIVEP1 3 0.01 2.73 0.21 5.00
155 INT329323 ecs Positive_regulation of Gene_expression of Il6 1 0.00 0.52 0.21 5.00
156 INT332304 Binding of Il6 and Adipoq 1 0.03 0.4 0.2 5.00
157 INT252366 Binding of RUNX1 and CD80 1 0.01 0.54 0.2 5.00
158 INT205710 CAMP Positive_regulation of P2rx7 1 0.02 0.47 0.19 5.00
159 INT279507 Serping1 Negative_regulation of Gene_expression of C3 1 0.03 1.12 0.19 5.00
160 INT279500 Serping1 Negative_regulation of Transcription of C3 1 0.03 1.12 0.19 5.00
161 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 5.00
162 INT355504 ANGPT2 Positive_regulation of CYBB 1 0.01 0.81 0.18 5.00
163 INT198649 Binding of HIF1A and MIF 1 0.01 1.53 0.18 5.00
164 INT274386 Binding of CD4 and ERVW-1 1 0.05 3.07 0.18 5.00
165 INT252367 Binding of RUNX1 and CTLA4 1 0.02 0.48 0.18 5.00
166 INT264101 Binding of CYP2D6 and Bche 1 0.07 0.33 0.18 5.00
167 INT179504 Tlr4 Regulation of Myd88 1 0.07 0.29 0.17 5.00
168 INT329324 KNG1 Positive_regulation of Localization of ecs 1 0.00 1.16 0.17 5.00
169 INT252646 Binding of C6orf25 and SYT16 1 0.00 0.51 0.17 5.00
170 INT197499 Binding of Apoe and Tfrc 1 0.14 1.54 0.17 5.00
171 INT179506 Tlr4 Regulation of Cd14 1 0.20 0.29 0.17 5.00
172 INT179501 Tlr4 Regulation of Nfkb1 1 0.05 0.3 0.17 5.00
173 INT353041 IL4 Positive_regulation of Localization of IL1B 1 0.02 0.99 0.16 5.00
174 INT353036 IL4 Positive_regulation of Localization of IL10 1 0.03 0.99 0.16 5.00
175 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16 5.00
176 INT353040 IL4 Positive_regulation of IL8 1 0.02 0.99 0.16 5.00
177 INT353037 IL4 Positive_regulation of IL2 1 0.02 0.99 0.16 5.00
178 INT292615 Binding of IL6 and SLC17A5 1 0.01 1.8 0.16 5.00
179 INT353038 IL4 Positive_regulation of Localization of IL2 1 0.02 0.99 0.16 5.00
180 INT353039 IL4 Positive_regulation of Localization of IL8 1 0.02 0.99 0.16 5.00
181 INT240768 Binding of F2 and F13A1 1 0.07 2.25 0.15 5.00
182 INT198638 GPI Positive_regulation of Gene_expression of TNF 1 0.03 1.44 0.15 5.00
183 INT241772 AVP Positive_regulation of ADCY1 1 0.09 1.08 0.15 5.00
184 INT205712 CAMP Positive_regulation of Localization of Il1 1 0.00 0.32 0.14 5.00
185 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
186 INT234604 Tlr4 Positive_regulation of Ptges 1 0.04 0 0.14 5.00
187 INT229088 IL1R1 Positive_regulation of Gene_expression of IL6 1 0.04 0.45 0.14 5.00
188 INT329371 IL8 Negative_regulation of Jun 1 0.00 0.95 0.13 5.00
189 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13 5.00
190 INT198671 HIF1A Regulation of Positive_regulation of Epo 1 0.00 1.37 0.13 5.00
191 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13 5.00
192 INT179234 Binding of SERPINA6 and ELANE 1 0.01 0.22 0.12 5.00
193 INT307627 Binding of BMP1 and CSF2 1 0.01 0.33 0.12 5.00
194 INT329317 ACE Regulation of Positive_regulation of KNG1 1 0.02 1.05 0.12 5.00
195 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12 5.00
196 INT174820 IL6 Positive_regulation of VEGFA 1 0.20 3.32 0.12 5.00
197 INT329325 ACE Regulation of Negative_regulation of Agtr2 1 0.01 0.93 0.12 5.00
198 INT174821 VEGFA Positive_regulation of Gene_expression of IL6 1 0.20 3.13 0.12 5.00
199 INT229089 IL1R1 Positive_regulation of IL6 1 0.03 0.45 0.12 5.00
200 INT352497 AGT Positive_regulation of Binding of CRS 1 0.14 0.87 0.11 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Cv General 2 Under Development. They are ordered first by their pain relevance and then by number of times they were reported in Cv General 2 Under Development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41 100.00
2 INT118267 Negative_regulation of ARSD 14 0.36 8.27 1.44 100.00
3 INT7132 Localization of NPPA 53 0.81 19.79 10.86 100.00
4 INT59859 Localization of ARSD 11 0.65 9.67 1.88 100.00
5 INT16357 Negative_regulation of NPPA 23 0.58 12.37 2.98 100.00
6 INT59593 Regulation of Gene_expression of NPPA 2 0.41 2.51 0.36 100.00
7 INT162831 Regulation of ARSD 13 0.35 6.17 1.19 100.00
8 INT162006 Positive_regulation of Gene_expression of ASAP1 7 0.44 3.3 0.13 100.00
9 INT239403 Regulation of Negative_regulation of ARSD 1 0.37 0.79 0 100.00
10 INT20348 Negative_regulation of Tbxa2r 47 0.59 19.88 7.68 100.00
11 INT132702 Binding of ASD1 2 0.03 1.71 0.63 100.00
12 INT154230 Regulation of Gene_expression of ARSD 2 0.35 1.01 0.14 100.00
13 INT154229 Gene_expression of ARSD 22 0.57 12.5 6.19 100.00
14 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89 100.00
15 INT57720 Localization of IGHG3 33 0.74 20.24 6.25 100.00
16 INT47010 Negative_regulation of Gusb 6 0.43 4.16 1.2 100.00
17 INT158059 Negative_regulation of ASD1 2 0.08 1.11 0.4 100.00
18 INT108501 Binding of ARSD 14 0.32 11.5 2.93 100.00
19 INT151743 Binding of Gusb 11 0.24 8.73 1.63 100.00
20 INT68189 Gene_expression of TNNT1 27 0.75 14.87 4.03 100.00
21 INT191706 Positive_regulation of Gene_expression of TNNT1 5 0.49 3.61 0.64 100.00
22 INT234473 Gene_expression of HDAC4 8 0.18 6.28 0.99 100.00
23 INT51028 Regulation of Il1b 28 0.60 21.15 12.47 100.00
24 INT45622 Gene_expression of Lss 1 0.52 0.16 0.15 100.00
25 INT52818 Localization of NR3C1 13 0.69 7.65 4.57 100.00
26 INT221520 Negative_regulation of Gene_expression of DLD 1 0.04 0.27 0 100.00
27 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 99.98
28 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 99.96
29 INT7298 Gene_expression of NPPA 35 0.70 18.23 4.76 99.92
30 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.92
31 INT11858 Localization of Tbxa2r 39 0.80 21.24 7.09 99.92
32 INT16371 Positive_regulation of Gene_expression of NPPA 7 0.45 3.62 0.96 99.92
33 INT28209 Positive_regulation of Localization of Tbxa2r 4 0.58 1.36 0.64 99.92
34 INT12161 Positive_regulation of P2rx2 70 0.69 34.22 34.4 99.92
35 INT116705 Positive_regulation of Positive_regulation of P2rx2 13 0.49 9.44 9.47 99.92
36 INT126324 Positive_regulation of CYB5R4 1 0.20 0.35 0.3 99.92
37 INT11042 Localization of Tbxa2r 26 0.76 10.15 7.24 99.90
38 INT20575 Gene_expression of Akr1d1 48 0.57 6.2 22.5 99.90
39 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 99.88
40 INT170625 Binding of SERPINA5 8 0.32 8.42 0.69 99.88
41 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23 99.84
42 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91 99.84
43 INT44550 Positive_regulation of Gene_expression of AVP 38 0.70 22.27 8.62 99.84
44 INT17056 Gene_expression of DLD 37 0.57 13.15 5.47 99.84
45 INT84700 Positive_regulation of HSP90B2P 34 0.67 30.22 4.07 99.80
46 INT38686 Binding of NR3C1 20 0.48 9.25 5.99 99.76
47 INT171070 Positive_regulation of Hey2 8 0.05 10.12 1.96 99.76
48 INT53374 Binding of Edn1 17 0.43 11.66 2.98 99.72
49 INT85297 Positive_regulation of Gene_expression of TNNI3 29 0.50 29.77 1.68 99.70
50 INT144201 Transcription of HSP90B2P 2 0.29 0.95 0 99.68
51 INT26972 Negative_regulation of Tenc1 57 0.57 56.71 16.87 99.68
52 INT316095 Negative_regulation of TLX1NB 1 0.23 0.68 0.19 99.66
53 INT314 Positive_regulation of Ren 212 0.70 66.68 55.56 99.66
54 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49 99.64
55 INT151123 Negative_regulation of Gene_expression of Csf2 21 0.53 21.76 3.22 99.64
56 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 99.64
57 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47 99.64
58 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6 99.60
59 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67 99.60
60 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 99.52
61 INT86437 Binding of IL6 154 0.48 121.22 29.3 99.48
62 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 99.44
63 INT9550 Gene_expression of TNNI3 113 0.78 86.79 10.56 99.36
64 INT49932 Gene_expression of Ptger3 33 0.71 8.77 7.39 99.36
65 INT10852 Transcription of AVP 3 0.69 1.75 1.41 99.32
66 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 99.30
67 INT11121 Positive_regulation of NPPA 64 0.70 34.09 11.96 99.28
68 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 99.28
69 INT9110 Binding of PAH 32 0.41 42.1 3.1 99.28
70 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81 99.24
71 INT195676 Negative_regulation of KAT8 2 0.19 2.63 0.23 99.18
72 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.16
73 INT239610 Localization of KCNQ1 4 0.62 1.47 0.2 99.16
74 INT174663 Positive_regulation of KAT8 4 0.11 3.45 0.22 99.14
75 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15 99.12
76 INT94196 Negative_regulation of Phosphorylation of MAPK1 60 0.59 31.64 9.16 99.12
77 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77 99.08
78 INT2828 Positive_regulation of Ptger3 26 0.68 8.01 9.63 99.08
79 INT24961 Positive_regulation of Defb22 8 0.03 3.56 6.04 99.08
80 INT316096 Binding of TLX1NB 1 0.20 2.08 0.38 99.00
81 INT172870 Negative_regulation of Ptger3 6 0.23 2.96 1.48 98.88
82 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 98.82
83 INT685 Regulation of AVP 124 0.62 34.9 39.91 98.80
84 INT82859 Gene_expression of Lalba 3 0.41 1.46 0.9 98.76
85 INT82861 Positive_regulation of Gene_expression of Lalba 3 0.30 1.46 0.9 98.76
86 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 98.76
87 INT82858 Regulation of Gene_expression of Lalba 1 0.19 0.77 0.1 98.76
88 INT46643 Negative_regulation of HYAL1 7 0.37 4.65 1.55 98.72
89 INT127914 Gene_expression of AGTR2 23 0.68 26.87 4.69 98.70
90 INT51262 Positive_regulation of TKT 7 0.69 4.31 0.82 98.64
91 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 98.64
92 INT55002 Gene_expression of ASAP1 46 0.64 22.8 3.2 98.58
93 INT73508 Negative_regulation of Gene_expression of ISYNA1 32 0.51 19.67 7.57 98.52
94 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 98.48
95 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 98.44
96 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 98.44
97 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 98.42
98 INT58288 Positive_regulation of Gene_expression of Crp 83 0.61 82.23 23.7 98.42
99 INT45427 Positive_regulation of Cacna2d2 20 0.49 11.89 4.85 98.40
100 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17 98.40
101 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99 98.40
102 INT1108 Gene_expression of PPY 58 0.75 36.57 10.76 98.36
103 INT52523 Positive_regulation of Adora3 2 0.49 1.39 1.79 98.36
104 INT157226 Positive_regulation of Gene_expression of Tnnc1 11 0.49 6.21 0.57 98.36
105 INT174958 Negative_regulation of Chuk 21 0.25 8.73 2.96 98.28
106 INT49266 Positive_regulation of Arigg4 37 0.47 53.79 11.2 98.24
107 INT20264 Gene_expression of Chkb 29 0.46 13.14 13.65 98.24
108 INT77290 Gene_expression of asa 15 0.33 10.17 4.97 98.24
109 INT27170 Gene_expression of Maoa 13 0.67 3.88 7.5 98.22
110 INT16396 Negative_regulation of CEBPZ 76 0.48 30.03 21.6 98.12
111 INT334119 Regulation of Negative_regulation of CEBPZ 1 0.08 0.64 0 98.12
112 INT53040 Binding of Agtr1a 22 0.47 7.36 4.15 98.04
113 INT292747 Positive_regulation of Gene_expression of Hspbp1 1 0.02 1.9 0.23 98.04
114 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 98.00
115 INT78579 Negative_regulation of P2rx3 23 0.59 10.13 10.78 97.96
116 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 97.96
117 INT10016 Negative_regulation of CD8A 81 0.42 56.68 13.15 97.84
118 INT3793 Regulation of CEBPZ 59 0.61 20.91 15.83 97.82
119 INT292746 Gene_expression of Hspbp1 1 0.02 1.89 0.23 97.74
120 INT47997 Negative_regulation of Positive_regulation of Hrh3 2 0.38 0.91 0.89 97.72
121 INT93789 Gene_expression of Tnnc1 28 0.76 17.3 1.99 97.68
122 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 97.60
123 INT145168 Negative_regulation of Serpina3a 2 0.17 1.17 0.18 97.54
124 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 97.52
125 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98 97.44
126 INT137277 Gene_expression of Acads 2 0.77 1.08 0.05 97.44
127 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54 97.40
128 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26 97.36
129 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 97.36
130 INT174100 Gene_expression of YWHAE 14 0.31 12.42 0.08 97.36
131 INT214 Localization of AVP 370 0.81 208.51 91.09 97.32
132 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 97.32
133 INT255129 Localization of Dmpk 5 0.65 3.1 0.07 97.28
134 INT102076 Regulation of DST 15 0.22 10 3.5 97.24
135 INT3182 Negative_regulation of PPY 12 0.42 4.65 2.28 97.24
136 INT1430 Regulation of PDYN 88 0.60 16.99 60.32 97.20
137 INT45283 Positive_regulation of VN1R4 3 0.17 1.9 0.31 97.20
138 INT47998 Positive_regulation of Hrh3 4 0.70 1.12 1.51 97.16
139 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 97.16
140 INT50855 Gene_expression of TRIM21 4 0.65 3.07 0.71 96.76
141 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 96.76
142 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 96.72
143 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 96.72
144 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 96.64
145 INT16356 Regulation of NPPA 33 0.62 13.24 9.53 96.64
146 INT17879 Positive_regulation of Ppap2a 17 0.53 9.72 3.8 96.64
147 INT53501 Negative_regulation of Positive_regulation of Ppap2a 1 0.01 0.7 0.29 96.64
148 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 96.56
149 INT102251 Positive_regulation of Positive_regulation of Crp 24 0.58 29.62 7.5 96.56
150 INT738 Regulation of POMC 459 0.62 111.19 243.74 96.56
151 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36 96.48
152 INT220326 Negative_regulation of FECD7 4 0.05 2.79 0 96.44
153 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 96.36
154 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 96.36
155 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 96.32
156 INT5742 Negative_regulation of Dob2 11 0.37 4.18 1.58 96.24
157 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 96.20
158 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21 96.20
159 INT11493 Positive_regulation of KLK1 21 0.67 9.22 5 96.20
160 INT21962 Localization of KLK1 15 0.78 3.54 1.61 96.20
161 INT120062 Binding of AIP 4 0.42 28.86 3.91 96.16
162 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42 96.16
163 INT104678 Positive_regulation of Ptges 18 0.34 6.29 3.39 96.08
164 INT1377 Positive_regulation of Trh 172 0.70 40.55 69.83 96.04
165 INT57098 Positive_regulation of Sdsl 1 0.11 0.71 0.11 96.04
166 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 96.04
167 INT43947 Localization of ASAP1 11 0.68 4.49 0.88 96.00
168 INT228332 Localization of FIG4 3 0.33 1.03 0.2 96.00
169 INT10166 Localization of Tnf 237 0.81 153.95 88.64 96.00
170 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78 96.00
171 INT33220 Negative_regulation of ras 110 0.58 70.21 9.19 95.96
172 INT53500 Negative_regulation of Ppap2a 11 0.45 3.31 1.92 95.92
173 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 95.76
174 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75 95.76
175 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 95.60
176 INT684 Binding of AVP 38 0.48 13.9 8.85 95.52
177 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64 95.48
178 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03 95.48
179 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39 95.44
180 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 95.28
181 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 95.28
182 INT287798 Localization of AIP 1 0.63 5.96 1.31 95.12
183 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 95.12
184 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95 95.08
185 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 94.96
186 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 94.88
187 INT22597 Positive_regulation of TF 43 0.68 27.27 5.17 94.88
188 INT36580 Positive_regulation of LCN1 9 0.45 5.63 1.02 94.88
189 INT191862 Phosphorylation of Tlr4 17 0.79 6.89 1.74 94.84
190 INT148395 Gene_expression of Gnb3 2 0.63 0.5 0.28 94.80
191 INT265369 Gene_expression of Ss18 1 0.12 3.81 0 94.80
192 INT195442 Gene_expression of FIG4 23 0.65 5.13 6.92 94.76
193 INT6361 Localization of Edn1 30 0.81 19.09 9.7 94.76
194 INT9842 Binding of F2 36 0.47 22.79 4.42 94.76
195 INT112989 Gene_expression of AIP 3 0.56 25.4 4.23 94.72
196 INT287799 Positive_regulation of Gene_expression of AIP 1 0.42 7.39 1.19 94.72
197 INT11120 Negative_regulation of Gene_expression of NPPA 2 0.39 1.45 0.06 94.68
198 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 94.68
199 INT28872 Positive_regulation of CSRP1 49 0.70 47.23 11.7 94.64
200 INT174685 Negative_regulation of Tnpo1 1 0.03 1.18 0.48 94.64
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