D:Decubitus Ulcers

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Disease Term
Synonyms BED SORE, Bed Sores, BEDSORE, Bedsores, Contact Ulcer, Contact Ulcers, Decubitus, Decubitus Pressure Sore, DECUBITUS PRESSURE SORES, Decubitus Skin Ulcer, Decubitus Skin Ulcers
Documents 936
Hot Single Events 61
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Decubitus Ulcers. They are ordered first by their relevance to Decubitus Ulcers and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT192678 PTEN Regulation of Dync1h1 1 0.02 0.5 0.03 84.56
2 INT272024 Gene_expression of GOPC Positive_regulation of Localization of COL7A1 1 0.10 0.86 0.14 63.36
3 INT185358 Binding of MCS and PCS 7 0.22 3.34 0.57 30.24
4 INT318387 Binding of Slc40a1 and Hrct1 1 0.02 0.88 0.08 12.68
5 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 5.00
6 INT194513 Timp1 Negative_regulation of Cpox 1 0.00 0.9 1.31 5.00
7 INT231732 Negative_regulation of Binding of Tnfrsf11a and Tnfsf11 1 0.01 1.03 0.48 5.00
8 INT231733 Binding of Tnfrsf11a and Tnfsf11 1 0.01 1.03 0.48 5.00
9 INT171990 Binding of DMD and VDR 5 0.05 2.58 0.39 5.00
10 INT355018 Binding of FAS and Faslg 1 0.12 1.34 0.37 5.00
11 INT191799 PROC Negative_regulation of Binding of F2r 1 0.00 0.92 0.3 5.00
12 INT257577 CALCA Positive_regulation of DMD 1 0.01 0.57 0.26 5.00
13 INT228611 Binding of DNMT3B and LEP 1 0.04 0 0.25 5.00
14 INT191792 Binding of F2r and Serpinc1 1 0.00 3.74 0.24 5.00
15 INT221353 Tnf Positive_regulation of Gene_expression of RT1-CE1 1 0.05 0.39 0.16 5.00
16 INT221352 Tnf Negative_regulation of Il1a 1 0.05 0.3 0.15 5.00
17 INT274474 IL12A Regulation of Gene_expression of VEGFA 1 0.04 0.36 0.14 5.00
18 INT274472 IL12A Negative_regulation of Gene_expression of FGF2 1 0.02 0.36 0.14 5.00
19 INT274473 IL12A Regulation of Gene_expression of FGF2 1 0.02 0.36 0.14 5.00
20 INT307529 Binding of IK and TRNAC1 1 0.00 0.07 0.12 5.00
21 INT355023 Phosphorylation of Rtn4r Negative_regulation of Binding of Mag and Rtn4r 1 0.00 0.38 0.11 5.00
22 INT274471 IL12A Negative_regulation of Gene_expression of IL10 1 0.02 0.99 0.1 5.00
23 INT355008 Binding of Mag and Rtn4r 1 0.02 0.36 0.1 5.00
24 INT274470 Binding of IL12A and GOPC 1 0.02 0.6 0.09 5.00
25 INT355019 Lif Positive_regulation of JAK1 1 0.00 0.69 0.08 5.00
26 INT355021 Cntf Positive_regulation of SOAT1 1 0.02 0.7 0.08 5.00
27 INT355022 Cntf Positive_regulation of JAK1 1 0.00 0.69 0.08 5.00
28 INT355009 Cntf Positive_regulation of Il6st 1 0.02 0.69 0.08 5.00
29 INT355020 Lif Positive_regulation of SOAT1 1 0.02 0.7 0.08 5.00
30 INT355010 Lif Positive_regulation of Il6st 1 0.02 0.69 0.08 5.00
31 INT274469 IL12A Positive_regulation of Gene_expression of IL6 1 0.04 1.39 0.06 5.00
32 INT251944 Binding of GH1 and PRNP 1 0.09 1.14 0.05 5.00
33 INT228610 Binding of DNMT3B and ASPRV1 1 0.02 0 0.05 5.00
34 INT181168 Binding of CD79A and TAPBP 1 0.10 0.7 0.04 5.00
35 INT218240 Binding of SAE1 and Dync1h1 1 0.00 0.17 0 5.00
36 INT189396 MBD4 Regulation of C11orf2 1 0.05 0.66 0 5.00
37 INT181169 TAPBP Negative_regulation of MALT1 1 0.00 0.48 0 5.00
38 INT181167 TAPBP Negative_regulation of CD79A 1 0.11 0.48 0 5.00
39 INT342265 Binding of VDR and HHIP 1 0.00 0.93 0 5.00
40 INT257589 Negative_regulation of Pth Positive_regulation of DMD 1 0.01 0 0 5.00
41 INT257590 Pth Positive_regulation of DMD 2 0.02 0.44 0 5.00
42 INT181165 TAPBP Regulation of Gene_expression of CD79A 1 0.07 0.35 0 5.00
43 INT211067 Pth Regulation of DMD 1 0.01 0.12 0 5.00
44 INT274475 IL12A Regulation of Gene_expression of IL6 1 0.04 0.68 0 5.00
45 INT332159 Gh Positive_regulation of Gene_expression of Igfbp3 1 0.07 1.11 0 5.00
46 INT265501 Binding of SGCB and SGCD 1 0.00 1.41 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Decubitus Ulcers. They are ordered first by their pain relevance and then by number of times they were reported in Decubitus Ulcers. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT242903 Gene_expression of SPI1 5 0.13 9.68 0.63 100.00
2 INT304667 Positive_regulation of SPI1 2 0.13 4.7 0.09 100.00
3 INT80141 Negative_regulation of SPI1 6 0.08 5.44 0.34 100.00
4 INT242889 Binding of SPI1 15 0.36 7.37 0.69 100.00
5 INT351181 Positive_regulation of Gene_expression of SPI1 1 0.10 1.87 0 100.00
6 INT322953 Localization of SPI1 2 0.13 2.17 0 100.00
7 INT351182 Positive_regulation of Binding of SPI1 1 0.08 1.25 0.09 100.00
8 INT144972 Positive_regulation of B4galt4 1 0.05 0.78 0.33 99.92
9 INT177831 Gene_expression of HDAC1 24 0.65 21.37 8.37 99.60
10 INT81216 Binding of RPL3P4 2 0.33 0.34 1.18 99.36
11 INT139780 Binding of AQP1 7 0.32 4.62 0.54 99.28
12 INT27188 Negative_regulation of Tcn2 5 0.18 1.33 0.83 99.08
13 INT80038 Positive_regulation of Gene_expression of MYC 24 0.67 13.93 5.17 98.80
14 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79 98.76
15 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36 98.60
16 INT175035 Gene_expression of Mecom 11 0.65 10.1 0.19 98.60
17 INT31341 Positive_regulation of CSE 15 0.60 11.57 12.29 98.40
18 INT8663 Positive_regulation of EDN2 3 0.38 0.65 0.5 96.68
19 INT285198 Positive_regulation of VGLL1 1 0.60 0.83 0.49 96.48
20 INT67048 Gene_expression of ITGA4 58 0.75 28.93 10.16 96.24
21 INT67332 Negative_regulation of ITGA4 8 0.51 7.95 2.14 96.24
22 INT10918 Gene_expression of ITGB2 93 0.76 71.8 16.34 95.84
23 INT67333 Negative_regulation of ITGB2 10 0.41 6.92 3.06 95.84
24 INT20286 Positive_regulation of Dob2 16 0.24 5.04 0.41 95.64
25 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 95.54
26 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 94.20
27 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 94.20
28 INT22095 Negative_regulation of Dync1h1 11 0.48 5.17 1.08 93.84
29 INT135289 Negative_regulation of Akr1b3 4 0.58 5.35 1.15 93.52
30 INT108708 Binding of Nrp1 3 0.27 3.51 1.08 93.40
31 INT16214 Localization of F13A1 36 0.74 21.8 4.87 91.84
32 INT38252 Positive_regulation of Hcm 7 0.40 9.96 0.59 91.48
33 INT234 Binding of Alb 151 0.48 52.34 32.97 91.40
34 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 90.92
35 INT281996 Negative_regulation of Transcription of TMEM200A 1 0.16 0.36 0.09 89.40
36 INT74145 Localization of CPQ 2 0.68 1.7 1.01 89.16
37 INT281994 Transcription of TMEM200A 4 0.30 1.36 0.35 88.96
38 INT335179 Negative_regulation of Sftpd 1 0.21 2.61 0.06 88.36
39 INT192676 Binding of PTEN 14 0.46 10.58 3.06 88.24
40 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 87.52
41 INT175034 Positive_regulation of Mecom 3 0.09 3.05 0 87.32
42 INT30 Gene_expression of Gast 158 0.78 99 41.45 86.24
43 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 86.12
44 INT27591 Negative_regulation of Gene_expression of Alb 30 0.58 17.03 5.99 84.88
45 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36 84.88
46 INT2405 Negative_regulation of SGCA 15 0.57 6.04 2.45 84.72
47 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 84.60
48 INT153313 Regulation of Localization of F13A1 2 0.36 2.34 0.48 84.36
49 INT10145 Gene_expression of Plg 28 0.62 12.68 7.46 84.16
50 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 83.92
51 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52 83.92
52 INT4587 Negative_regulation of Serping1 32 0.47 19.11 5.92 82.32
53 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 82.08
54 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 81.96
55 INT1127 Negative_regulation of IGHG3 32 0.28 21.1 7.37 81.96
56 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7 81.96
57 INT1126 Negative_regulation of CD79A 46 0.59 31.07 6 81.96
58 INT35143 Negative_regulation of ANGPTL5 28 0.54 18.59 3.14 81.96
59 INT35269 Localization of SGCG 38 0.78 14.68 9.01 81.52
60 INT167018 Negative_regulation of POR 3 0.37 1.9 0.11 81.16
61 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 80.36
62 INT155889 Binding of Nps 22 0.42 9.79 2.6 79.92
63 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 79.24
64 INT177643 Binding of CENPJ 12 0.36 8.59 0.22 79.12
65 INT159127 Gene_expression of Nps 49 0.75 16.91 12.06 78.52
66 INT231734 Transcription of RP29 1 0.05 0.15 0.04 78.32
67 INT35349 Gene_expression of CENPJ 52 0.57 25.36 2.54 78.24
68 INT29229 Regulation of NCOR2 20 0.42 5.75 8.08 77.32
69 INT177642 Positive_regulation of Gene_expression of CENPJ 5 0.30 3.25 0.07 76.80
70 INT77052 Negative_regulation of Wbp2nl 1 0.37 0.22 0.16 76.16
71 INT7465 Negative_regulation of Mbp 53 0.58 19.12 13.27 75.08
72 INT8339 Negative_regulation of GC 12 0.57 4.9 1.37 75.08
73 INT27907 Gene_expression of Pip 6 0.60 1.35 1.53 75.00
74 INT65642 Binding of Dync1h1 27 0.41 15.83 2.68 74.96
75 INT5219 Negative_regulation of DBP 43 0.57 23.35 4.26 74.16
76 INT6852 Localization of TNF 883 0.81 705.95 270.84 74.04
77 INT121386 Positive_regulation of MSSE 3 0.40 1.29 0.42 73.68
78 INT332981 Regulation of Nrp1 1 0.15 0.84 0.09 72.00
79 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 71.84
80 INT29 Negative_regulation of Gast 74 0.59 24.85 24.96 70.24
81 INT60547 Localization of Iapp 5 0.80 9.9 0.65 70.16
82 INT221509 Positive_regulation of Dse 1 0.41 0.92 0.15 69.92
83 INT8660 Positive_regulation of Positive_regulation of EDN2 2 0.38 0.23 0.22 68.96
84 INT44608 Gene_expression of C2 45 0.75 15.84 5.05 68.20
85 INT323040 Gene_expression of EDN2 1 0.32 0.13 0.13 67.76
86 INT78251 Positive_regulation of LBP 38 0.69 39.98 26.73 67.44
87 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 66.76
88 INT443 Localization of POMC 1020 0.81 284.52 443.17 66.72
89 INT18872 Negative_regulation of Asap1 18 0.43 8.48 5.42 65.96
90 INT39507 Positive_regulation of TXNRD1 37 0.68 12.47 14.25 65.48
91 INT124643 Binding of DYNLL1 3 0.36 0.9 0.23 65.12
92 INT68907 Regulation of AICDA 4 0.44 0.77 0.47 65.04
93 INT19293 Protein_catabolism of FN1 7 0.95 5.15 2.97 64.96
94 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 64.56
95 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34 62.72
96 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 62.64
97 INT214692 Negative_regulation of Gene_expression of FUT3 3 0.24 2.2 0.17 61.52
98 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 61.48
99 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 61.48
100 INT83891 Gene_expression of FUT3 20 0.61 10.49 1.41 61.08
101 INT2144 Localization of COL7A1 36 0.74 20.92 4.67 58.72
102 INT38971 Positive_regulation of Gene_expression of Gtf3a 27 0.60 18.25 7.77 58.48
103 INT81972 Positive_regulation of Dse 20 0.57 16.5 2.99 58.32
104 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47 57.80
105 INT189397 Gene_expression of NXNL1 1 0.03 1.26 0.07 57.60
106 INT62509 Gene_expression of MCS 58 0.67 21.46 6.57 56.68
107 INT167070 Positive_regulation of Gene_expression of MCS 3 0.30 3.75 1.48 56.68
108 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 56.24
109 INT12104 Positive_regulation of PLG 45 0.68 28.94 4.81 55.60
110 INT122041 Binding of Ppara 308 0.48 189.17 51.48 54.88
111 INT285195 Binding of VGLL1 1 0.32 0.34 0.23 54.32
112 INT33008 Gene_expression of Dync1h1 41 0.68 23.85 3.82 52.56
113 INT117349 Binding of Mecom 4 0.31 5.38 0.32 50.00
114 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 49.24
115 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 49.24
116 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 49.24
117 INT2732 Gene_expression of VIP 74 0.78 24.57 33.72 49.24
118 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 49.24
119 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 49.24
120 INT67331 Gene_expression of C1QL1 1 0.75 0.42 0.43 49.24
121 INT32903 Negative_regulation of PPAP2A 14 0.48 5.02 7.2 47.20
122 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 46.16
123 INT3911 Gene_expression of TNFAIP1 29 0.65 21.68 1.85 42.84
124 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 42.72
125 INT92343 Negative_regulation of CENPJ 20 0.57 6.25 0.2 42.48
126 INT59722 Negative_regulation of Slc40a1 3 0.11 0.56 1.73 40.12
127 INT318386 Negative_regulation of Gene_expression of Slc40a1 1 0.11 0.48 0.09 40.12
128 INT327714 Localization of CNC 1 0.10 0.79 0.09 40.08
129 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35 39.88
130 INT132882 Gene_expression of Slc40a1 4 0.17 1.35 1.6 38.08
131 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5 37.20
132 INT30039 Negative_regulation of HAL 7 0.42 4.32 1.61 36.80
133 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57 36.64
134 INT22083 Regulation of Pth 55 0.62 22.32 8.9 35.76
135 INT35765 Gene_expression of TXNRD1 47 0.56 9.16 4.43 35.44
136 INT22738 Negative_regulation of DYNLL1 17 0.57 6.68 2.06 33.20
137 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 32.80
138 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 31.04
139 INT88868 Binding of MCS 45 0.40 37.43 7.98 30.24
140 INT194073 Gene_expression of Gpx6 22 0.09 10.02 1.62 29.84
141 INT14572 Binding of INS 205 0.48 175.43 13.38 29.72
142 INT134346 Binding of PCS 51 0.37 22.27 5.67 29.60
143 INT86999 Regulation of DYNLL1 5 0.44 2.85 2.18 29.40
144 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83 26.88
145 INT181325 Positive_regulation of TNFAIP1 4 0.36 4.64 0.52 23.08
146 INT6947 Negative_regulation of Gene_expression of POMC 37 0.59 10.32 14.14 22.24
147 INT61784 Positive_regulation of CENPJ 27 0.51 11.46 2.28 20.28
148 INT2659 Positive_regulation of Psgb1 2 0.40 3.25 0.3 20.28
149 INT350956 Binding of Psgb1 1 0.03 1.64 0.08 19.72
150 INT285196 Gene_expression of VGLL1 1 0.58 0 0 17.56
151 INT323038 Regulation of Positive_regulation of EDN2 1 0.21 0 0.1 16.44
152 INT132529 Binding of TAPBP 8 0.47 1.43 0.18 13.32
153 INT23012 Negative_regulation of Nrp1 4 0.35 0.69 0.63 12.84
154 INT21032 Gene_expression of Adh1 23 0.78 22.1 6.14 10.16
155 INT119330 Binding of Calcrl 8 0.37 1.96 3.85 9.28
156 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 5.44
157 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 5.44
158 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 5.00
159 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
160 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 5.00
161 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
162 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
163 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 5.00
164 INT477 Localization of Avp 813 0.81 131.58 300.4 5.00
165 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 5.00
166 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 5.00
167 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
168 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
169 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
170 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 5.00
171 INT1893 Localization of Gh 1041 0.79 340.23 256.58 5.00
172 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
173 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
174 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
175 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 5.00
176 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 5.00
177 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 5.00
178 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 5.00
179 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 5.00
180 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 5.00
181 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 5.00
182 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 5.00
183 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
184 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 5.00
185 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 5.00
186 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
187 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
188 INT425 Localization of PRL 455 0.81 189.64 144.8 5.00
189 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
190 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 5.00
191 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 5.00
192 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 5.00
193 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 5.00
194 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 5.00
195 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 5.00
196 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
197 INT4207 Regulation of Avp 267 0.62 63.72 115.33 5.00
198 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34 5.00
199 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
200 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
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