D:Deficiency Diseases

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pChart

Disease Term
Synonyms Deficiency Disease, Disease Deficiency, Diseases Deficiency
Documents 35
Hot Single Events 9
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Deficiency Diseases. They are ordered first by their relevance to Deficiency Diseases and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
2 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79 5.00
3 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48 5.00
4 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34 5.00
5 INT300727 IL25 Positive_regulation of IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
6 INT300732 IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
7 INT300728 IL33 Positive_regulation of IL4 1 0.00 0 0.33 5.00
8 INT300729 IL18 Positive_regulation of IL13 1 0.00 0 0.33 5.00
9 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3 5.00
10 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3 5.00
11 INT314305 Ptger2 Positive_regulation of Nos2 1 0.00 0.07 0.26 5.00
12 INT300753 Binding of Cd28 and Positive_regulation of Transcription of IL13 1 0.00 0 0.17 5.00
13 INT300731 IL10 Negative_regulation of Gene_expression of IGHE 1 0.03 0.23 0.13 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Deficiency Diseases. They are ordered first by their pain relevance and then by number of times they were reported in Deficiency Diseases. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT686 Negative_regulation of Sct 35 0.59 9.59 11.32 99.72
2 INT4880 Regulation of MME 17 0.61 7.78 8.2 98.68
3 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 98.52
4 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 98.48
5 INT158 Localization of Prl 2431 0.81 378.96 952.2 98.32
6 INT98226 Negative_regulation of Cd79a 5 0.49 3.99 2.66 95.76
7 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 91.76
8 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 91.20
9 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 90.16
10 INT7133 Negative_regulation of MME 85 0.59 29.22 33.1 77.76
11 INT2364 Localization of Sct 134 0.80 26.21 41.47 75.00
12 INT288 Positive_regulation of Sct 88 0.70 32.83 24.5 75.00
13 INT3173 Negative_regulation of Localization of Sct 28 0.55 6.46 12.11 75.00
14 INT4587 Negative_regulation of Serping1 32 0.47 19.11 5.92 75.00
15 INT149841 Positive_regulation of Negative_regulation of Sct 1 0.50 0.47 0.13 75.00
16 INT50595 Positive_regulation of HRASLS 16 0.49 9.65 4.24 74.52
17 INT164975 Binding of ELN 6 0.35 6.38 0.64 68.92
18 INT22871 Gene_expression of ELN 30 0.68 14.86 1.33 67.96
19 INT338125 Gene_expression of GET4 1 0.29 2.74 0.32 67.80
20 INT10870 Regulation of IgG 67 0.59 43.27 12.74 64.24
21 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68 56.80
22 INT108780 Positive_regulation of Gene_expression of Ptger2 94 0.49 59.71 16.22 56.80
23 INT47075 Positive_regulation of Ptger2 142 0.70 78.55 25.47 54.24
24 INT300747 Positive_regulation of Negative_regulation of IGHE 1 0.41 0.63 0 51.28
25 INT62041 Negative_regulation of Gene_expression of IGHE 37 0.58 37.86 5.27 40.16
26 INT300748 Negative_regulation of Negative_regulation of IGHE 1 0.38 0.55 0 40.16
27 INT98609 Negative_regulation of PYGM 11 0.43 6.21 0.6 35.60
28 INT221431 Negative_regulation of FOXP3 8 0.40 9.92 1.98 33.56
29 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 31.32
30 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01 31.32
31 INT263492 Positive_regulation of Regulation of Hand2 3 0.19 4.76 0.21 31.32
32 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 30.92
33 INT112017 Regulation of Hand2 77 0.36 62.23 18.04 30.92
34 INT249854 Localization of CD200 2 0.65 0.4 0 5.48
35 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
36 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
37 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 5.00
38 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
39 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
40 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
41 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
42 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03 5.00
43 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
44 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
45 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 5.00
46 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 5.00
47 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
48 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 5.00
49 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
50 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 5.00
51 INT9993 Positive_regulation of Gene_expression of IL2 131 0.69 46.27 30.04 5.00
52 INT8775 Binding of IGHE 167 0.48 102.61 23.54 5.00
53 INT66281 Transcription of Nos2 81 0.71 39.49 20.37 5.00
54 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 5.00
55 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 5.00
56 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86 5.00
57 INT77433 Regulation of Gene_expression of Nos2 49 0.62 35.07 16.33 5.00
58 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 5.00
59 INT56447 Positive_regulation of Icam1 64 0.64 64.14 16.16 5.00
60 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 5.00
61 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 5.00
62 INT25396 Localization of Ptger2 83 0.78 46.81 14.81 5.00
63 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 5.00
64 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 5.00
65 INT173505 Localization of Hand2 63 0.57 45.32 13.66 5.00
66 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 5.00
67 INT69436 Negative_regulation of Gene_expression of ROS1 81 0.38 46.58 12.22 5.00
68 INT69158 Localization of IL4 48 0.71 31.3 11.98 5.00
69 INT701 Localization of IGHE 87 0.80 40.5 10.62 5.00
70 INT15804 Gene_expression of ISG20 83 0.75 44.33 10.58 5.00
71 INT94784 Binding of ROS1 113 0.40 71.57 10.26 5.00
72 INT85966 Gene_expression of Cd40lg 50 0.73 30.9 9.11 5.00
73 INT9548 Gene_expression of CHKB 99 0.65 50.86 9.03 5.00
74 INT2971 Regulation of IGHE 42 0.61 28.81 7.87 5.00
75 INT93003 Binding of CD40 28 0.47 20.25 7.13 5.00
76 INT49506 Regulation of Ptger2 29 0.44 17.38 6.75 5.00
77 INT132822 Localization of IL13 26 0.67 22.85 6.66 5.00
78 INT73499 Positive_regulation of IL13 23 0.39 20.03 6.53 5.00
79 INT38672 Binding of KRT20 69 0.39 48.01 6.31 5.00
80 INT2890 Positive_regulation of MB 39 0.70 29.58 6.01 5.00
81 INT17551 Positive_regulation of Gene_expression of HLA-DRA 31 0.70 15.39 6 5.00
82 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 5.00
83 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45 5.00
84 INT56299 Transcription of IL4 15 0.64 10.2 5.44 5.00
85 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38 5.00
86 INT171562 Regulation of IL4 19 0.36 12.12 5.33 5.00
87 INT56445 Regulation of Icam1 14 0.39 15.4 5.32 5.00
88 INT72747 Localization of IgG 55 0.53 30.88 4.19 5.00
89 INT170738 Binding of Icam1 23 0.37 25.49 4.09 5.00
90 INT16165 Regulation of DMD 114 0.60 35.13 3.64 5.00
91 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6 5.00
92 INT9999 Regulation of Gene_expression of IGHE 32 0.60 15.75 3.53 5.00
93 INT73500 Regulation of IL13 12 0.36 10.37 3.53 5.00
94 INT188355 Binding of Cd28 25 0.34 8.29 3.38 5.00
95 INT85971 Positive_regulation of Gene_expression of Cd40lg 14 0.66 7.61 3.29 5.00
96 INT117754 Gene_expression of NHS 34 0.57 9.27 3.28 5.00
97 INT9549 Regulation of CHKB 25 0.47 13.61 3.2 5.00
98 INT38673 Negative_regulation of KRT20 38 0.42 22.49 2.77 5.00
99 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 5.00
100 INT28815 Gene_expression of Ighd 18 0.65 11.02 2.48 5.00
101 INT4210 Gene_expression of MB 24 0.78 11.74 2.32 5.00
102 INT129240 Positive_regulation of Stat6 6 0.67 1.96 1.92 5.00
103 INT117330 Negative_regulation of Binding of ROS1 13 0.37 8.33 1.67 5.00
104 INT93956 Binding of HBM 20 0.35 8.86 1.48 5.00
105 INT100672 Transcription of Hand2 9 0.42 2.84 1.47 5.00
106 INT179169 Transcription of IL13 11 0.15 4.22 1.37 5.00
107 INT9081 Positive_regulation of Positive_regulation of IGHE 5 0.42 7.13 1 5.00
108 INT192686 Positive_regulation of Positive_regulation of DMD 8 0.41 4.66 0.93 5.00
109 INT114017 Gene_expression of CD200 10 0.75 2.38 0.88 5.00
110 INT102231 Localization of HBM 8 0.60 6.14 0.88 5.00
111 INT62155 Positive_regulation of Gene_expression of DMD 17 0.67 6.17 0.82 5.00
112 INT2395 Binding of MB 18 0.36 7.53 0.68 5.00
113 INT137858 Binding of NHS 14 0.32 2.94 0.57 5.00
114 INT314285 Gene_expression of Icosl 1 0.01 0.06 0.54 5.00
115 INT58571 Positive_regulation of ALDOB 6 0.49 5.63 0.53 5.00
116 INT125821 Regulation of Positive_regulation of IGHE 6 0.40 5.38 0.53 5.00
117 INT114018 Binding of CD200 5 0.47 2.12 0.52 5.00
118 INT147823 Localization of H1fnt 3 0.35 2.35 0.41 5.00
119 INT160506 Binding of Icam5 3 0.24 3.21 0.4 5.00
120 INT135720 Gene_expression of War 7 0.34 3.99 0.28 5.00
121 INT166177 Gene_expression of H1fnt 5 0.48 4.64 0.26 5.00
122 INT184624 Localization of CDKN2A 8 0.74 7.87 0.25 5.00
123 INT314286 Positive_regulation of Nfyb 1 0.01 0.06 0.25 5.00
124 INT314287 Binding of Icam2 1 0.04 0.64 0.23 5.00
125 INT10060 Negative_regulation of MB 7 0.42 2.51 0.22 5.00
126 INT338126 Transcription of GET4 1 0.30 0.22 0.2 5.00
127 INT310097 Positive_regulation of H1fnt 4 0.24 2.28 0.18 5.00
128 INT284968 Positive_regulation of CDA 2 0.05 0.34 0.15 5.00
129 INT338124 Positive_regulation of GET4 1 0.22 0.17 0.15 5.00
130 INT341251 Regulation of H1fnt 3 0.21 0.69 0.1 5.00
131 INT341107 Negative_regulation of Localization of ELN 1 0.41 0.66 0.1 5.00
132 INT274185 Localization of ELN 4 0.73 1.25 0.1 5.00
133 INT300743 Regulation of MS4A2 1 0.00 0.62 0.06 5.00
134 INT338123 Phosphorylation of GET4 1 0.35 0.22 0 5.00
135 INT300746 Gene_expression of MS4A2 1 0.01 0.25 0 5.00
136 INT341253 Negative_regulation of Gene_expression of H1fnt 1 0.17 0.72 0 5.00
137 INT341249 Negative_regulation of Regulation of H1fnt 1 0.17 0.35 0 5.00
138 INT300749 Binding of MS4A2 1 0.00 0.38 0 5.00
139 INT341248 Positive_regulation of Gene_expression of H1fnt 1 0.20 0.87 0 5.00
140 INT341250 Positive_regulation of Positive_regulation of H1fnt 1 0.20 0.32 0 5.00
141 INT184623 Positive_regulation of Localization of CDKN2A 1 0.04 0.86 0 5.00
142 INT184621 Regulation of ALDOB 1 0.01 1.15 0 5.00
143 INT354026 Positive_regulation of ICOS 1 0.17 2.32 0 5.00
144 INT341252 Regulation of Gene_expression of H1fnt 1 0.18 0.36 0 5.00
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