D:Dementia

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pChart

Disease Term
Synonyms Amentia, AMENTIAS, Degeneration Frontotemporal Lobar, Degenerations Frontotemporal Lobar, Dementia Familial, Dementia Semantic, Dementias, Dementias Familial, DEMENTIAS SEMANTIC, DEMENTIAS SENILE PARANOID, Depressive Pseudodementia
Documents 2789
Hot Single Events 200
Hot Interactions 41

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Dementia. They are ordered first by their relevance to Dementia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT325429 Mapt Positive_regulation of Csf2 1 0.13 1.29 0 99.92
2 INT215342 Binding of Cebpg and Tbp 1 0.00 0.55 0 99.92
3 INT261391 Binding of Nsdhl and P4hb 1 0.02 1.3 0.1 99.56
4 INT88080 Binding of Chrna4 and Psmb6 1 0.03 0.56 0.46 99.52
5 INT325428 Csf2 Regulation of Mapt 1 0.08 1.47 0 99.10
6 INT249992 Binding of Lnpep and Igkv4-55 1 0.01 0.47 0 98.68
7 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13 98.00
8 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13 98.00
9 INT261380 Nsdhl Negative_regulation of P4hb 1 0.02 1.36 0.11 96.56
10 INT60523 Binding of IL1B and TNFRSF1A 1 0.25 1.73 0.21 96.24
11 INT340743 Negative_regulation of CSF2 Positive_regulation of ZNF807 1 0.00 1.77 0 94.88
12 INT340745 CSF2 Positive_regulation of ZNF807 1 0.00 1.76 0 94.88
13 INT325433 Binding of Csf2 and Mapt 1 0.12 4.41 0 94.68
14 INT250151 Binding of GSS and MCM3 1 0.01 1.38 0.04 93.44
15 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 91.44
16 INT273047 Binding of Aqp4 and Sct 1 0.04 1.41 0 91.08
17 INT325431 Positive_regulation of Binding of Csf2 and Mapt 1 0.18 1.49 0 91.04
18 INT335742 Binding of PDB1 and Dpyd 1 0.02 1.75 0.09 90.96
19 INT250150 Binding of IKBKG and SACM1L 1 0.00 2.78 0.06 90.40
20 INT250153 Binding of PRNP and IKBKG 1 0.09 2.83 0.06 90.40
21 INT282712 Binding of MUC5AC and Csf2 1 0.01 2.63 1.07 89.12
22 INT282711 Binding of Csf2 and Mmp9 1 0.16 1.35 0.54 89.12
23 INT286476 Binding of App and Itm2b 1 0.47 5.24 0.14 88.68
24 INT149541 Binding of GCA and TADA1 1 0.40 1.4 0.13 88.40
25 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53 87.20
26 INT99842 Edn1 Negative_regulation of Localization of Ren 1 0.24 0.43 0.32 86.84
27 INT99843 Edn3 Negative_regulation of Localization of Ren 1 0.25 0.42 0.31 86.84
28 INT261390 Binding of Nsdhl and Bdnf 1 0.05 1.33 0.12 86.48
29 INT308648 Binding of sps and Gopc 1 0.01 2.71 0 86.32
30 INT335743 Binding of PDB1 and Salpa1 1 0.01 1.66 0.09 86.24
31 INT282713 Binding of MUC5AC and Mmp9 1 0.02 1.27 0.52 86.08
32 INT262714 ACOT1 Positive_regulation of Negative_regulation of ACHE 1 0.06 1.41 0.08 85.96
33 INT348972 Binding of CSF2 and MOG 1 0.21 0.41 0 85.16
34 INT311229 DPP4 Positive_regulation of Gene_expression of INS 1 0.32 0.57 0 85.12
35 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33 84.96
36 INT269057 Il6 Positive_regulation of Crp 1 0.37 1.83 0.51 84.44
37 INT303337 Binding of SOD1 and Igfals 1 0.06 1.27 0.08 84.00
38 INT174140 Binding of EBM and SEC31A 1 0.02 0.08 0 82.96
39 INT174133 Binding of Igfals and Sod1 3 0.19 3 0.08 81.76
40 INT60524 IFNGR2 Positive_regulation of FERMT2 1 0.04 1.87 0.25 80.84
41 INT184814 NOS3 Positive_regulation of Gene_expression of NOS1 1 0.09 0.54 0.1 80.24
42 INT193784 ITIH4 Positive_regulation of YWHAZ 1 0.04 1.21 0.34 79.88
43 INT309568 Binding of Kdm5d and TUG1 1 0.13 0.3 0.08 78.96
44 INT107917 RETNLB Positive_regulation of Gene_expression of App 1 0.01 1.2 0.79 78.88
45 INT353848 Binding of SCLY and Ubash3a 1 0.30 0.47 0.04 78.44
46 INT321683 Binding of Aicda and Mapt 1 0.36 1.23 0.04 77.88
47 INT323611 Il1 Regulation of Hmgb1 1 0.17 2.36 0.55 77.88
48 INT269061 Binding of Il6 and Il6ra 3 0.04 2.59 0.45 77.00
49 INT269066 Binding of Hspa8 and Il6 1 0.00 0.74 0.23 77.00
50 INT264134 Binding of IFNA1 and Tlr4 1 0.01 1.5 0.22 76.68
51 INT308534 Binding of HIVEP1 and Alms1 1 0.00 0.96 0.13 76.48
52 INT123260 Binding of Gabrg2 and Serpini1 1 0.02 0.63 1.16 76.08
53 INT123261 Gabrg2 Regulation of Serpini1 1 0.01 0.63 1.16 76.08
54 INT348971 Binding of MOG and CARTPT 1 0.06 0.73 0.08 74.28
55 INT193778 ITIH4 Positive_regulation of CASP3 1 0.03 0.98 0.03 73.84
56 INT141224 Ache Regulation of Acot1 1 0.09 0.29 0.14 73.72
57 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 73.20
58 INT19476 Binding of IL1A and Il6 1 0.00 2.19 0.36 72.84
59 INT19477 Binding of IL1A and Csf2 1 0.00 2.19 0.36 72.84
60 INT339585 Binding of AMD1 and MDM1 1 0.06 2.02 0 72.20
61 INT325432 Vsnl1 Positive_regulation of Csf2 1 0.19 1.07 0 71.76
62 INT251701 Bche Regulation of Gene_expression of Acot1 1 0.03 0.25 0.03 71.68
63 INT265646 Binding of Mapk1 and Mapk14 1 0.01 1.53 0.46 71.52
64 INT265647 Binding of Ephb1 and Mapk1 1 0.00 1.48 0.43 71.52
65 INT325430 Vsnl1 Positive_regulation of Vhl-ps1 1 0.03 1.01 0 70.88
66 INT340742 Positive_regulation of CSF2 Regulation of BDNF 1 0.22 1.46 0.14 70.44
67 INT249988 Agt Regulation of Ca2 1 0.18 0.9 0.04 70.12
68 INT340744 CSF2 Regulation of BDNF 1 0.13 1.45 0.14 70.08
69 INT81159 Binding of PARP1 and IgG-2a 1 0.00 1.02 0.21 69.00
70 INT296867 Binding of B4galnt2 and Mtor 1 0.00 0.51 0 68.60
71 INT206081 IL6ST Negative_regulation of IL6 1 0.11 0.81 0.17 68.16
72 INT261371 Nsdhl Negative_regulation of Positive_regulation of Bdnf 1 0.06 1.18 0.09 68.08
73 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 67.52
74 INT188746 Binding of CSF2 and HIVEP1 1 0.04 3.99 0.21 66.56
75 INT189844 Churc1 Positive_regulation of Cnr2 1 0.01 0.79 1.02 64.48
76 INT355687 Art2b Positive_regulation of Gene_expression of Mc3r 1 0.02 1.01 0.48 64.24
77 INT261577 Nos2 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.16 64.16
78 INT88311 ITIH4 Positive_regulation of CCR5 1 0.49 1.57 0.16 63.80
79 INT88310 ITIH4 Positive_regulation of CXCR4 2 0.27 1.98 0.23 63.44
80 INT27393 Tha1 Negative_regulation of Ache 1 0.15 0.24 0.14 63.44
81 INT303335 Binding of Igfals and CHMP2B 1 0.05 1.3 0 61.52
82 INT215341 Binding of Htt and Sp1 1 0.03 0.25 0 61.44
83 INT210225 Ptpn2 Positive_regulation of Gene_expression of Ifng 1 0.15 1.44 0.42 61.04
84 INT235125 PDE2A Negative_regulation of Twist1 1 0.00 0.99 0.24 61.04
85 INT339582 AMD1 Regulation of C1QTNF5 1 0.07 2 0 60.64
86 INT265879 IGF1 Regulation of FOXO1 1 0.11 1.37 0.03 60.48
87 INT265884 IGF1 Regulation of CREB1 1 0.13 1.31 0.03 59.68
88 INT265906 IGF1 Regulation of Gsk3b 1 0.25 1.31 0.03 59.20
89 INT261398 Nsdhl Positive_regulation of Binding of Nsdhl and Med1 1 0.01 2.14 0.09 58.88
90 INT261393 Binding of Nsdhl and Med1 1 0.02 1 0.04 58.88
91 INT269071 Binding of IL6 and Il6 1 0.40 0.73 0.19 58.64
92 INT230500 Il1 Positive_regulation of Gene_expression of Tnf 1 0.07 1.83 0.4 57.32
93 INT230501 Il1 Positive_regulation of Gene_expression of S100a8 1 0.01 1.82 0.39 57.32
94 INT261396 Nsdhl Positive_regulation of Transcription of Esr1 1 0.02 2.1 0.09 56.64
95 INT310229 Binding of INS and SUCLA2 1 0.07 4.69 0 56.20
96 INT265891 IGF1 Regulation of AKT1 1 0.05 1.24 0.03 56.08
97 INT265880 IGF1 Regulation of PIK3CG 1 0.10 1.23 0.03 55.76
98 INT253637 TNF Regulation of Transcription of HIVEP1 1 0.07 1.72 0.26 55.20
99 INT237419 Binding of Hif1a and Bace1 Positive_regulation of Bace1 1 0.06 1.2 0.15 54.88
100 INT237418 Binding of Hif1a and Bace1 1 0.06 1.18 0.15 54.88
101 INT237420 Binding of Hif1a and Bace1 Positive_regulation of Positive_regulation of Bace1 1 0.06 1.2 0.15 54.88
102 INT270431 Gnrh1 Positive_regulation of APP 1 0.06 0.51 0.03 54.88
103 INT298996 Il18 Positive_regulation of Gene_expression of Cdk5r1 1 0.03 1.65 0.29 54.76
104 INT298995 Il18 Positive_regulation of Gene_expression of Cdk5 1 0.12 1.65 0.29 54.76
105 INT299008 Il18 Positive_regulation of Transcription of Cdk5 1 0.12 1.65 0.29 54.76
106 INT299011 Il18 Positive_regulation of Transcription of Cdk5r1 1 0.03 1.65 0.29 54.76
107 INT206088 IL6 Positive_regulation of JAK1 1 0.18 0.05 0 54.76
108 INT348137 Binding of GYPE and Gpi 1 0.01 1.29 0.29 54.68
109 INT270432 Lhb Positive_regulation of APP 1 0.03 0.51 0.03 54.04
110 INT316054 Eif1 Positive_regulation of Il6 1 0.00 0.78 0.21 50.20
111 INT316062 Ps Positive_regulation of Il6 1 0.04 0.77 0.21 50.20
112 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 50.00
113 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 50.00
114 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23 50.00
115 INT165583 Binding of Bdnf and Ngf 3 0.33 0.81 0.69 50.00
116 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65 50.00
117 INT308656 Pik3r1 Positive_regulation of Nos3 1 0.02 1.8 0.5 50.00
118 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46 50.00
119 INT308653 Proc Regulation of Gene_expression of Mapk8 1 0.00 1.48 0.36 50.00
120 INT308667 Binding of Chrm1 and Positive_regulation of Binding of App 1 0.04 1.14 0.32 50.00
121 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31 50.00
122 INT308661 Akt1 Positive_regulation of Chuk 1 0.02 0.6 0.25 50.00
123 INT308670 Positive_regulation of CYBB Positive_regulation of Gene_expression of Ros1 1 0.00 0.68 0.23 50.00
124 INT238802 Binding of Ager and Renbp 6 0.02 6.46 0.22 50.00
125 INT308650 Binding of nt and Ntrk2 1 0.01 0.41 0.21 50.00
126 INT308654 Binding of Ngfr and Nts 1 0.06 0.39 0.21 50.00
127 INT308645 Binding of Esr1 and Itpr3 1 0.00 0 0.2 50.00
128 INT308646 Car2 Regulation of Gene_expression of Ins1 1 0.00 0 0.19 50.00
129 INT308669 CREB1 Regulation of Gene_expression of Ins1 1 0.01 0 0.19 50.00
130 INT308657 Creb1 Regulation of Gene_expression of Ins1 1 0.01 0 0.19 50.00
131 INT308659 Binding of Ager and ecs 1 0.01 1.14 0.12 50.00
132 INT308647 Ager Positive_regulation of Gene_expression of Bace1 1 0.09 1.01 0.12 50.00
133 INT308660 Binding of Ager and App 1 0.08 1.22 0.12 50.00
134 INT308651 Binding of Igf1 and Ins1 1 0.02 0.22 0.11 50.00
135 INT308662 Binding of Esr1 and Fdft1 1 0.00 0.05 0.09 50.00
136 INT308666 Binding of Lrp1 and Chol1 1 0.10 0.69 0.09 50.00
137 INT308652 Binding of Renbp and Nps 1 0.01 1.38 0.09 50.00
138 INT308655 Binding of Lrp1 and Gopc 1 0.01 0.49 0.07 50.00
139 INT308665 Binding of Apoe and Gopc 1 0.02 0.49 0.07 50.00
140 INT308663 Apoe Regulation of Car2 1 0.02 0.44 0.07 50.00
141 INT308649 Binding of Ppp1r13b and Iars 1 0.01 0.29 0.04 50.00
142 INT308658 Binding of Apoa2 and Apoe 1 0.17 0.15 0.03 50.00
143 INT308643 Binding of Proc and Renbp 1 0.00 1.61 0 50.00
144 INT308664 Akt1 Positive_regulation of Phosphorylation of Insr 1 0.02 0.43 0 50.00
145 INT121225 Positive_regulation of Ngf Positive_regulation of Ntrk1 2 0.49 0 0 50.00
146 INT316063 Ps Positive_regulation of IL8 1 0.09 1.33 0.41 49.20
147 INT316065 Eif1 Positive_regulation of IL8 1 0.01 1.34 0.41 49.20
148 INT141223 Bche Regulation of Gene_expression of Acot1 1 0.09 0 0.1 49.20
149 INT308518 HSP90B1 Positive_regulation of Positive_regulation of SOAT1 1 0.00 0.65 0.18 48.24
150 INT141225 Bche Regulation of Acot1 1 0.09 0 0.1 48.24
151 INT249600 IFNA1 Positive_regulation of Gene_expression of Cd40 1 0.49 1.13 0.52 47.48
152 INT262716 Binding of ACHE and BCHE 1 0.09 0.11 0 45.12
153 INT198920 Binding of Ldlr and Lrpap1 1 0.05 0.06 0 44.56
154 INT320400 Binding of Vcp and Khdrbs1 1 0.01 0.07 0 43.60
155 INT268445 Olr1 Positive_regulation of Positive_regulation of Lipa 1 0.01 0.87 0 42.40
156 INT188702 St6galnac2 Positive_regulation of Gene_expression of Stab1 1 0.00 5.09 1.23 42.16
157 INT188695 St6galnac2 Positive_regulation of Stab1 1 0.00 2.53 0.61 41.84
158 INT188693 Regulation of St6galnac2 Positive_regulation of Stab1 1 0.00 2.64 0.61 41.84
159 INT188705 St6galnac2 Positive_regulation of Localization of Stab1 1 0.00 1.27 0.31 41.84
160 INT262619 Gopc Regulation of Gene_expression of ROS1 1 0.01 0.51 0 41.60
161 INT265893 BAD Regulation of FOXO1 1 0.03 1.08 0.06 40.16
162 INT334718 Binding of NOS1 and Bax 1 0.02 0.87 0 38.96
163 INT190751 Adcyap1 Positive_regulation of Vipr2 2 0.16 1.02 0.36 38.72
164 INT273048 Adcyap1 Positive_regulation of Adcyap1r1 1 0.11 1.02 0.19 38.72
165 INT264679 IGFALS Positive_regulation of CTSC 1 0.02 1.68 0 37.28
166 INT268446 Cdk5 Positive_regulation of Cdk5r1 1 0.02 0.58 0 36.28
167 INT317163 Htt Regulation of Bdnf 1 0.29 0.19 0 35.88
168 INT162754 Negative_regulation of Binding of APP and Slc30a2 1 0.00 1.26 0.04 35.28
169 INT162753 Binding of APP and Slc30a2 1 0.00 1.25 0.04 34.80
170 INT129920 IFNA2 Regulation of ADO 1 0.00 0.64 0.64 33.32
171 INT348970 Binding of MOG and HAND1 1 0.03 1.28 0.2 32.24
172 INT265883 IGF1 Positive_regulation of Transcription of FOXO1 1 0.17 1.14 0.07 31.20
173 INT257937 Binding of CSF2 and INVS 1 0.04 1.1 0.14 29.12
174 INT264683 Binding of VAPB and ALS2 1 0.29 1.1 0 28.80
175 INT265882 IGF1 Positive_regulation of Transcription of AKT1 1 0.08 1.13 0.07 28.72
176 INT264678 Binding of SETX and KRT20 1 0.00 2.17 0 28.20
177 INT209400 Binding of F13A1 and FGG 1 0.01 1.72 0.09 28.08
178 INT117203 Binding of IL1B and IL6 2 0.20 1.4 0.51 28.00
179 INT264682 Binding of VAPB and SETX 1 0.28 1.09 0 27.76
180 INT273046 Vip Negative_regulation of Gene_expression of Adcyap1 1 0.20 1.14 0.21 27.68
181 INT282708 Binding of MAPT and Y301C7L 1 0.00 0.54 0.16 25.72
182 INT204492 Negative_regulation of Binding of App and Fmr1 1 0.42 0.28 0 25.36
183 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18 25.00
184 INT129919 IFNA2 Positive_regulation of Gene_expression of SLC6A4 1 0.02 0.38 0.69 25.00
185 INT129921 IL4 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.38 0.68 25.00
186 INT120203 Binding of App and Il1 1 0.17 1.28 0.59 25.00
187 INT120204 Binding of App and Il1f5 1 0.09 1.28 0.59 25.00
188 INT120206 Binding of UTS2R and Il1 1 0.17 1.28 0.59 25.00
189 INT120207 Binding of UTS2R and Il1f5 1 0.09 1.28 0.59 25.00
190 INT270044 Il10 Positive_regulation of Positive_regulation of Hmox1 1 0.20 1.59 0.53 25.00
191 INT91751 Binding of PTGS2 and Hmox1 1 0.00 0.21 0.27 25.00
192 INT270046 Ido1 Positive_regulation of Positive_regulation of Hmox1 1 0.15 0.8 0.27 25.00
193 INT158141 Binding of HOXD13 and SNCA 1 0.54 0.41 0.11 25.00
194 INT265886 IGF1 Positive_regulation of AKT1 1 0.11 3.06 0.23 23.76
195 INT295918 Mir761 Regulation of Transcription of Ngf 1 0.02 0.49 0.2 23.52
196 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62 23.12
197 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62 23.12
198 INT305883 Pcx Negative_regulation of Binding of Tjp1 1 0.04 0.11 0.04 22.64
199 INT305875 Pcx Negative_regulation of Binding of Ocln 1 0.03 0.11 0.04 22.64
200 INT261376 Nsdhl Positive_regulation of Gene_expression of Nrgn 1 0.06 0.86 0.08 21.44

Single Events

The table below shows the top 200 pain related interactions that have been reported for Dementia. They are ordered first by their pain relevance and then by number of times they were reported in Dementia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 100.00
2 INT167182 Binding of Psd 9 0.41 13.08 1.06 100.00
3 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 100.00
4 INT4012 Negative_regulation of Psd 23 0.52 14.12 3.81 100.00
5 INT303326 Gene_expression of CHMP2B 25 0.75 10.08 0.76 100.00
6 INT27207 Gene_expression of Psd 31 0.73 15.44 2.75 100.00
7 INT75627 Gene_expression of Mapt 41 0.75 22.1 4.58 100.00
8 INT334212 Negative_regulation of DLEU1 2 0.28 8.84 0.53 100.00
9 INT272956 Positive_regulation of Binding of Psd 1 0.28 2.66 0 100.00
10 INT203311 Positive_regulation of Gene_expression of Igfals 5 0.16 6.87 0.8 100.00
11 INT286474 Localization of ITM2B 2 0.47 5.27 1.21 100.00
12 INT161766 Localization of Psd 7 0.75 3.53 0.96 100.00
13 INT97216 Positive_regulation of Psd 13 0.45 7.04 1.25 100.00
14 INT272256 Protein_catabolism of Psd 3 0.49 2.66 0.19 100.00
15 INT286475 Positive_regulation of ITM2B 1 0.03 1.83 0.1 100.00
16 INT318932 Regulation of ATP7B 2 0.40 1.12 0.28 100.00
17 INT349751 Gene_expression of ATP7B 1 0.51 0.73 0.24 100.00
18 INT318933 Binding of ATP7B 2 0.37 0.96 0.03 100.00
19 INT334210 Negative_regulation of Negative_regulation of DLEU1 1 0.09 1.14 0 100.00
20 INT78329 Binding of ADC 7 0.31 7.57 0.73 100.00
21 INT203372 Positive_regulation of Igfals 10 0.40 9.24 1.11 100.00
22 INT259536 Transcription of Psd 2 0.38 1.25 0.16 100.00
23 INT188755 Positive_regulation of Binding of CSF2 6 0.44 8.79 0.35 100.00
24 INT72141 Binding of Apoe 11 0.37 10.91 3.27 100.00
25 INT231128 Gene_expression of HAND1 4 0.40 1.32 0.25 100.00
26 INT123532 Positive_regulation of RUNX1T1 3 0.45 0.72 0.08 100.00
27 INT200206 Negative_regulation of Gene_expression of Igfals 4 0.21 3.83 0.5 99.98
28 INT232667 Binding of Pd 17 0.16 20.76 3.58 99.98
29 INT96797 Negative_regulation of ITIH4 5 0.42 3.21 1.8 99.98
30 INT156696 Positive_regulation of Pain1 10 0.23 10.92 12.42 99.98
31 INT223032 Positive_regulation of Regulation of Pain1 1 0.05 0.98 0.9 99.98
32 INT23411 Negative_regulation of Tnip1 5 0.38 1.15 0.32 99.98
33 INT269109 Negative_regulation of Cyp2b10 2 0.08 2.9 0.17 99.98
34 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52 99.92
35 INT263689 Positive_regulation of Mapt 6 0.49 5.15 0.36 99.92
36 INT233467 Regulation of Itm2b 2 0.43 1.77 0.08 99.92
37 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 99.92
38 INT199276 Binding of Tbp 12 0.46 2.67 0.24 99.92
39 INT173422 Gene_expression of ETFDH 11 0.45 5.78 0.78 99.84
40 INT44647 Positive_regulation of TBXA2R 14 0.57 6.95 1.64 99.84
41 INT335733 Positive_regulation of Tardbp 8 0.69 28.41 0.41 99.84
42 INT186523 Binding of ETFDH 10 0.25 5.63 0.72 99.84
43 INT193855 Binding of Ps 8 0.07 3.15 0.25 99.84
44 INT14048 Negative_regulation of TKT 13 0.34 5.05 1.51 99.84
45 INT54383 Negative_regulation of Agps 6 0.35 3.2 1.13 99.82
46 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 99.80
47 INT118005 Regulation of Apoc4 2 0.02 1.42 0.89 99.80
48 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 99.76
49 INT3463 Gene_expression of Igfals 21 0.39 21.1 2.93 99.76
50 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 99.76
51 INT133085 Gene_expression of Mapk8ip1 7 0.66 6.13 2.98 99.76
52 INT17035 Positive_regulation of TFPI 55 0.61 34.88 14.18 99.76
53 INT14503 Binding of BCHE 13 0.48 3.95 1.85 99.74
54 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 99.72
55 INT48911 Binding of NOS1 24 0.40 11.21 5.89 99.72
56 INT25265 Transcription of HIVEP1 30 0.45 28.12 2.08 99.70
57 INT167521 Regulation of Pain1 11 0.27 10.88 14 99.70
58 INT233453 Gene_expression of Itm2b 8 0.74 8.45 0.99 99.66
59 INT14301 Binding of CSF2 82 0.48 67.95 8.98 99.64
60 INT169205 Gene_expression of Ps 23 0.58 15.88 9.99 99.64
61 INT248772 Negative_regulation of Binding of CSF2 4 0.39 5.16 0.19 99.64
62 INT15310 Gene_expression of DLEU1 8 0.67 20.57 0.96 99.56
63 INT148271 Regulation of SGCA 10 0.37 5.89 0.86 99.56
64 INT120483 Localization of ITIH4 11 0.69 12.05 2.51 99.52
65 INT315626 Localization of DLEU1 2 0.35 4.17 0.07 99.52
66 INT3127 Gene_expression of SRI 38 0.68 26.29 3.82 99.50
67 INT271762 Binding of HAND1 3 0.10 3.66 0.31 99.50
68 INT138700 Negative_regulation of Gene_expression of Ccl2 27 0.57 24.1 9.08 99.48
69 INT135407 Negative_regulation of Ccl2 33 0.57 32.74 9.45 99.48
70 INT277161 Gene_expression of UFD1L 1 0.78 8.73 0.39 99.48
71 INT261366 Binding of P4hb 1 0.04 1.3 0.1 99.48
72 INT303796 Gene_expression of Tdp1 1 0.77 70.15 2.55 99.46
73 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 99.44
74 INT340754 Negative_regulation of Negative_regulation of CSF2 1 0.31 1.25 0 99.44
75 INT6481 Binding of TNF 624 0.48 510.2 214.82 99.44
76 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 99.40
77 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 99.40
78 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 99.40
79 INT264054 Negative_regulation of Negative_regulation of Bche 6 0.41 2.49 0.04 99.40
80 INT75299 Binding of Atxn3 8 0.43 5.3 0.26 99.40
81 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.38
82 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 99.38
83 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 99.38
84 INT50080 Binding of APOE 38 0.45 29.61 2.67 99.36
85 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 99.36
86 INT295605 Gene_expression of Agps 1 0.06 1.03 0.03 99.36
87 INT295604 Negative_regulation of Gene_expression of Agps 1 0.04 0.55 0 99.36
88 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67 99.36
89 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 99.32
90 INT4742 Gene_expression of Tac1 177 0.78 69.99 102.66 99.32
91 INT6174 Regulation of Gene_expression of POMC 49 0.61 9.75 27.69 99.32
92 INT51206 Regulation of Gene_expression of Tac1 13 0.45 5.92 7.74 99.32
93 INT667 Negative_regulation of Hrh2 38 0.58 18.11 18.01 99.32
94 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5 99.28
95 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89 99.26
96 INT25 Positive_regulation of LAMC2 19 0.67 8.64 7.06 99.24
97 INT10855 Positive_regulation of Gene_expression of LAMC2 4 0.67 2.05 0.88 99.24
98 INT69992 Negative_regulation of Hmox2 93 0.50 49.01 44.07 99.20
99 INT13409 Gene_expression of NEUROD1 52 0.75 14.17 12.23 99.18
100 INT304218 Regulation of skt 1 0.03 0.73 0 99.16
101 INT4977 Binding of ITIH4 60 0.46 42.48 15.65 99.12
102 INT102428 Binding of C2 17 0.32 5.12 1.58 99.12
103 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 99.10
104 INT49556 Gene_expression of NOLC1 11 0.49 29.44 1.07 99.08
105 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41 99.08
106 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 99.06
107 INT340749 Positive_regulation of ZNF807 1 0.00 3.79 0 99.00
108 INT96588 Gene_expression of MOG 18 0.75 11.41 1.89 99.00
109 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 98.96
110 INT1893 Localization of Gh 1041 0.79 340.23 256.58 98.96
111 INT100912 Regulation of Kdm5d 52 0.32 20.39 4.72 98.96
112 INT939 Gene_expression of PAEP 86 0.77 31.02 8.59 98.92
113 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 98.92
114 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 98.92
115 INT90764 Positive_regulation of Furin 4 0.32 1.7 0.44 98.92
116 INT287536 Positive_regulation of Negative_regulation of BCHE 1 0.04 0.58 0 98.88
117 INT63042 Binding of Apoe 59 0.48 31.23 5.88 98.84
118 INT24296 Binding of NPY 6 0.48 2.03 3.23 98.82
119 INT142284 Gene_expression of Hrt1 2 0.13 4.77 0.34 98.80
120 INT202428 Positive_regulation of Binding of CD4 4 0.37 2.11 0.68 98.80
121 INT225670 Binding of CREBZF 2 0.23 3.4 0.15 98.76
122 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 98.72
123 INT22128 Positive_regulation of HIVEP1 61 0.43 70.52 6.07 98.70
124 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25 98.68
125 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 98.64
126 INT272837 Phosphorylation of Kctd1 1 0.11 1.56 0.07 98.64
127 INT33781 Binding of Pebp1 11 0.44 1.76 6.61 98.64
128 INT173179 Binding of MAPK14 13 0.29 4.51 2.92 98.60
129 INT151123 Negative_regulation of Gene_expression of Csf2 21 0.53 21.76 3.22 98.60
130 INT36287 Binding of CD4 96 0.47 58.93 11.88 98.60
131 INT55142 Positive_regulation of P4hb 3 0.36 1.38 0.28 98.54
132 INT29743 Negative_regulation of App 91 0.59 65.56 31.26 98.52
133 INT1154 Negative_regulation of CCK 24 0.59 9.3 15.32 98.52
134 INT15238 Positive_regulation of NPY 24 0.67 11.86 11.26 98.50
135 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 98.48
136 INT118716 Positive_regulation of MAPT 4 0.49 7.25 0.54 98.48
137 INT193805 Negative_regulation of Gene_expression of ITIH4 3 0.42 3.98 0.76 98.48
138 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 98.48
139 INT17277 Positive_regulation of Gene_expression of HIVEP1 25 0.67 21.79 6.7 98.48
140 INT65603 Positive_regulation of SRI 8 0.41 2.32 2.56 98.46
141 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 98.44
142 INT84932 Negative_regulation of APP 29 0.57 28.45 7.2 98.44
143 INT173979 Gene_expression of Cap1 3 0.42 2.17 0.22 98.44
144 INT173981 Gene_expression of Park7 2 0.56 0.73 0.1 98.44
145 INT145929 Regulation of Bax 20 0.60 18.12 5.35 98.40
146 INT134443 Binding of Bax 10 0.47 5.62 1.84 98.40
147 INT15132 Gene_expression of TNFRSF1A 33 0.75 20.09 5.93 98.40
148 INT55792 Regulation of Negative_regulation of Bche 11 0.57 1.78 3.21 98.36
149 INT246981 Gene_expression of DHDDS 2 0.10 0.6 0 98.36
150 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87 98.32
151 INT127122 Positive_regulation of Gene_expression of Snca 11 0.69 15.36 4.56 98.32
152 INT334211 Positive_regulation of Gene_expression of TARDBP 1 0.32 3.03 0 98.28
153 INT100861 Binding of CRP 179 0.48 175.2 26.45 98.28
154 INT246551 Negative_regulation of Serpinb12 1 0.01 2.57 0.17 98.28
155 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 98.24
156 INT169628 Binding of SNCA 4 0.47 3.53 0.36 98.24
157 INT284359 Negative_regulation of Mvk 4 0.37 6.62 0.99 98.24
158 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36 98.20
159 INT5653 Positive_regulation of ELANE 136 0.70 72.78 27.94 98.20
160 INT6666 Negative_regulation of PENK 30 0.58 9.16 17.91 98.20
161 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 98.12
162 INT217302 Localization of Neo1 2 0.09 0.99 0 98.12
163 INT162254 Regulation of BAG3 28 0.41 18.12 4.75 98.12
164 INT295904 Regulation of Mir761 1 0.05 1.91 0.12 98.00
165 INT62487 Localization of HIVEP1 35 0.73 36.24 2.72 97.96
166 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38 97.96
167 INT33567 Gene_expression of CALM1 139 0.67 48.85 56.14 97.92
168 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35 97.92
169 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 97.92
170 INT333080 Gene_expression of SAP30L 1 0.04 6.01 0.34 97.92
171 INT316045 Negative_regulation of Negative_regulation of Psen1 1 0.42 1.58 0.27 97.92
172 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 97.92
173 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 97.88
174 INT51083 Gene_expression of Adc 14 0.53 8.24 2.25 97.88
175 INT36177 Binding of Alms1 70 0.31 35.47 13.81 97.84
176 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 97.84
177 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 97.84
178 INT25022 Binding of PAEP 66 0.42 22.83 6.59 97.84
179 INT65965 Gene_expression of Adcyap1 52 0.78 22.53 13.14 97.80
180 INT15148 Gene_expression of Vip 51 0.77 25.61 18.33 97.80
181 INT15149 Positive_regulation of Gene_expression of Vip 2 0.44 3.53 1.25 97.80
182 INT120823 Positive_regulation of Gene_expression of Adcyap1 10 0.68 6.71 3.22 97.80
183 INT264685 Gene_expression of TARDBP 4 0.61 8.8 0.31 97.72
184 INT91100 Binding of SPTLC1 10 0.47 12.85 5.71 97.72
185 INT334213 Transcription of TARDBP 1 0.24 0.98 0 97.72
186 INT150132 Negative_regulation of CLDN5 3 0.05 3.03 1.7 97.72
187 INT1752 Negative_regulation of Ache 109 0.59 42.05 15.73 97.64
188 INT325424 Negative_regulation of Negative_regulation of Mapt 1 0.12 2.99 0.06 97.64
189 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 97.64
190 INT325426 Negative_regulation of Negative_regulation of Csf2 1 0.34 1.48 0.03 97.64
191 INT101474 Positive_regulation of Gene_expression of Gfap 61 0.70 38.3 10.35 97.64
192 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 97.60
193 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 97.60
194 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 97.52
195 INT3002 Binding of SUGT1 62 0.24 55.9 14.91 97.48
196 INT11030 Binding of LPA 70 0.48 40.35 4.81 97.48
197 INT158837 Binding of POLG 4 0.37 4.69 0.44 97.44
198 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 97.44
199 INT121110 Binding of neuropathy type 1 1 0.01 0.66 0.33 97.44
200 INT10847 Gene_expression of LAMC2 39 0.75 27 12.09 97.44
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