D:Diabetes Mellitus

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Disease Term
Synonyms DIABETES, Diabetes Hypertension, Diabetes Mellitus Type 1, Diabetes Mellitus Type 2, Diabetes Mellitus Type I, DIABETES MELLITUS TYPE II, Diabetes Mellitus Type Ii Obesity, Diabetic, Diabetics, Insulin Dependent Diabetes, Insulin Dependent Diabetes Mellitus
Documents 15330
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Diabetes Mellitus. They are ordered first by their relevance to Diabetes Mellitus and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT245193 Binding of TCF7L2 and Abpa 1 0.02 10.66 0 100.00
2 INT245185 Binding of RRAD and TCF7L2 1 0.00 6.88 0.1 100.00
3 INT245183 Binding of CTSB and TCF7L2 1 0.39 6.39 0.18 100.00
4 INT245194 Binding of RRAD and Abpa 1 0.00 6.29 0.13 100.00
5 INT260564 Binding of Nos3 and T2dm2 1 0.05 3.96 0 100.00
6 INT212770 Binding of CTD and TGFB1 1 0.01 3.95 0 100.00
7 INT340502 Agtr1a Negative_regulation of Phosphorylation of Jak2 1 0.12 2.32 0 100.00
8 INT172826 Binding of Tnfsf4 and T2dm2 1 0.00 5.97 0.22 100.00
9 INT210899 Binding of SELE and IGHD1-14 1 0.39 3.31 0.11 100.00
10 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 100.00
11 INT245182 Binding of SPINK1 and TCF7L2 1 0.39 2.05 0.1 100.00
12 INT289626 Binding of SNRNP70 and SUGT1 3 0.03 2.49 0 100.00
13 INT250553 Binding of RS1 and SUGT1 3 0.00 3.36 0.22 100.00
14 INT339043 SNRNP70 Regulation of PITX2 1 0.00 1.42 0 100.00
15 INT172825 Binding of Crp and T2dm2 1 0.00 4.5 0.62 100.00
16 INT204172 Regulation of Binding of Cs and Nox1 1 0.08 1.01 0.04 100.00
17 INT316414 Binding of LDLR and T2dm2 1 0.00 1.54 0 100.00
18 INT270655 Adipoq Positive_regulation of IL8 Positive_regulation of Adipoq 1 0.00 1.19 0.15 100.00
19 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4 100.00
20 INT172818 Binding of T2dm2 and Hypism 1 0.00 3.62 0.1 100.00
21 INT290877 Binding of Bcl2a1c and Lepr 1 0.00 0.87 0.04 100.00
22 INT74617 Binding of GCC1 and Nidds 1 0.00 1.43 0.07 100.00
23 INT131020 Binding of GNRH1 and T1DM 1 0.10 0.99 0.08 100.00
24 INT246914 Binding of CDKN2A and Ifng 1 0.01 0.71 0 100.00
25 INT185159 Binding of Retn and T2dm2 1 0.01 1.42 0.04 100.00
26 INT165724 Bdkrb1 Positive_regulation of Adora1 1 0.24 1.65 0.43 100.00
27 INT241027 Positive_regulation of Agtr2 Positive_regulation of Protein_catabolism of Sypl 1 0.00 0.85 0 100.00
28 INT339042 SNRNP70 Regulation of RS1 1 0.00 0.94 0 100.00
29 INT353865 Binding of CHI3L1 and Lepr 1 0.00 1.88 0.03 100.00
30 INT340504 Agtr1a Negative_regulation of Phosphorylation of Pik3cb 1 0.06 1.16 0 100.00
31 INT172838 Binding of ISL1 and T2dm2 1 0.00 2.41 0 100.00
32 INT344405 Binding of EGFR and Spp1 1 0.09 1.34 0 100.00
33 INT306238 Tead1 Regulation of Ins1 1 0.00 1.04 0.05 100.00
34 INT207259 Binding of CNBP and TXNIP 1 0.01 0.94 0 100.00
35 INT172824 Positive_regulation of Binding of Tnfsf4 and T2dm2 1 0.00 2.97 0.12 100.00
36 INT210898 IGHD1-14 Regulation of SELE 1 0.22 1.51 0 100.00
37 INT182804 Binding of ETV3 and T2DM 1 0.10 2.62 0 100.00
38 INT172820 Binding of Nfkb1 and T2dm2 1 0.00 2.14 0.17 100.00
39 INT172822 Binding of Fga and T2dm2 1 0.01 2.24 0.31 100.00
40 INT178969 Slc7a2 Regulation of Ins1 1 0.01 0.56 0.05 100.00
41 INT270667 Binding of Bcat1 and Prh1 1 0.01 0.89 0.12 100.00
42 INT172833 Binding of FFAR1 and T2dm2 1 0.00 1.55 0 100.00
43 INT172836 Binding of INS and T2dm2 1 0.00 1.65 0.08 100.00
44 INT210897 Binding of SNRNP70 and IGHD1-14 1 0.01 1.63 0.08 100.00
45 INT249849 Ufm1 Positive_regulation of Fgf2 1 0.01 0.56 0.14 100.00
46 INT249852 Ufm1 Positive_regulation of VEGFA 1 0.00 0.55 0.14 100.00
47 INT175911 Binding of SERPINE1 and CNBP 1 0.01 1.02 0.22 100.00
48 INT329956 Binding of IL2 and IL23R 1 0.33 4.58 1.21 100.00
49 INT173130 Binding of INS and PPARA 2 0.04 1.8 0.08 100.00
50 INT270657 Casp8 Regulation of Localization of Ins1 1 0.03 0.68 0 100.00
51 INT304885 Gene_expression of Ros1 Positive_regulation of Positive_regulation of Mapk1 1 0.14 0.52 0.06 100.00
52 INT152361 Binding of Ifng and T2dm2 1 0.00 0.86 0.37 100.00
53 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78 100.00
54 INT339048 SNRNP70 Regulation of PSORS2 1 0.00 0.45 0 100.00
55 INT283460 Binding of CTLA4 and DLAT 1 0.06 3.14 0.09 100.00
56 INT172831 Binding of INS and Tnfsf4 1 0.02 1.07 0 100.00
57 INT262994 Binding of CRP and HSD11B1 1 0.15 3.02 0.03 100.00
58 INT218616 Binding of IGFBP3 and INS 1 0.07 0.68 0.05 100.00
59 INT175909 Binding of ROS1 and CNBP 1 0.01 1.78 0.19 100.00
60 INT175908 Binding of NOS3 and ROS1 1 0.10 1.84 0.19 100.00
61 INT352518 Binding of FAT1 and Adipoq 1 0.01 2.79 0.2 100.00
62 INT262997 Binding of HSD11B1 and ADIPOQ 1 0.54 2.82 0.07 100.00
63 INT348175 Binding of NIDDM1 and PTPN22 1 0.01 2.36 0.99 100.00
64 INT241021 Agtrap Positive_regulation of Gopc 1 0.19 0.19 0 100.00
65 INT170560 Binding of Renbp and Narf 1 0.01 1.69 0.27 100.00
66 INT321979 Negative_regulation of Klk1c8 Negative_regulation of Positive_regulation of Ins1 1 0.04 0.81 0.22 100.00
67 INT321980 Negative_regulation of Dpp4 Negative_regulation of Positive_regulation of Ins1 1 0.16 0.81 0.22 100.00
68 INT329963 Binding of IL21 and IL23R 1 0.30 2.28 0.6 100.00
69 INT172835 Binding of AGT and T2dm2 1 0.00 1.73 0 100.00
70 INT172839 Binding of ANGPT2 and T2dm2 1 0.00 1.72 0 100.00
71 INT174501 Binding of HLA-B and HLA-DOA 2 0.03 1.84 0.42 100.00
72 INT335851 Snrpc Positive_regulation of Il10 1 0.01 1.17 0.5 100.00
73 INT260565 T2dm2 Regulation of SUGT1 1 0.00 1.43 0.05 100.00
74 INT303749 Binding of Chrm3 and Chrm1 Negative_regulation of Gene_expression of Chat 1 0.03 1.12 0.19 100.00
75 INT284519 NOVA2 Positive_regulation of Gene_expression of CX3CL1 1 0.07 1.49 0.2 100.00
76 INT194134 Binding of HLA-E and IGAD1 1 0.02 1.01 0.15 100.00
77 INT194136 Binding of HLA-E and INS 1 0.01 0.95 0.15 100.00
78 INT194135 Binding of CD79A and HLA-E 1 0.07 1.01 0.15 100.00
79 INT352500 Binding of FAT1 and INS 1 0.01 1.38 0.1 100.00
80 INT283463 Binding of DLAT and GAGE4 1 0.00 1.1 0.03 100.00
81 INT349173 Positive_regulation of Stzid Positive_regulation of Positive_regulation of Hspb1 1 0.03 0.3 0 100.00
82 INT246912 Binding of Ifng and Igf2bp2 1 0.01 0.6 0 99.96
83 INT343914 Hmgb1 Positive_regulation of Gene_expression of IL12A 1 0.01 0.41 0.24 99.96
84 INT343906 Hmgb1 Positive_regulation of Gene_expression of Cd40 1 0.05 0.41 0.24 99.96
85 INT255044 GLP1R Positive_regulation of Localization of INS 3 0.49 1.47 0.22 99.92
86 INT270669 Adipoq Positive_regulation of IL8 1 0.01 1.06 0.12 99.92
87 INT270665 Adipoq Positive_regulation of Ccl2 1 0.07 1.06 0.12 99.92
88 INT270663 Adipoq Positive_regulation of Il6 1 0.02 1.05 0.12 99.92
89 INT125768 Positive_regulation of GLP1R Regulation of INS 1 0.48 0.71 0 99.92
90 INT332631 Negative_regulation of Dpp4 Negative_regulation of Gcg 1 0.05 1 0.05 99.92
91 INT332628 Negative_regulation of Dpp4 Negative_regulation of Positive_regulation of Gcg 1 0.05 1 0.05 99.92
92 INT200641 Binding of ACE and Agtr1a 1 0.12 0.92 0.06 99.92
93 INT200638 Binding of ACE and Agtr2 1 0.10 0.93 0.06 99.92
94 INT235623 Binding of INS and INSR 1 0.14 0.47 0 99.92
95 INT339044 Binding of PITX2 and SUGT1 1 0.00 2.25 0 99.88
96 INT200637 Binding of Abpa and Ace 1 0.01 4.62 0.22 99.84
97 INT31308 Positive_regulation of Ghrh Regulation of Gh1 1 0.14 0.69 0.1 99.84
98 INT279620 Negative_regulation of Binding of Grin2a and Grin2b 1 0.18 0.99 0.4 99.84
99 INT311223 GLP1R Regulation of Localization of GCG 1 0.16 0.74 0 99.84
100 INT232575 SNRNP70 Regulation of SOD1 1 0.12 0.65 0 99.84
101 INT330120 Bdkrb2 Regulation of Bdkrb1 1 0.19 1.26 0.38 99.84
102 INT300437 Kdr Regulation of Gene_expression of Flt1 1 0.42 0.26 0 99.84
103 INT262641 Binding of HLA-DRA and AICDA 1 0.04 0.53 0 99.84
104 INT246803 Binding of Akt1 and Tsc2 1 0.14 0.85 0 99.82
105 INT141761 Nfkb1 Regulation of Positive_regulation of CADM1 1 0.01 1.21 0.16 99.82
106 INT141754 Nfkb1 Regulation of Positive_regulation of Ptgs2 1 0.16 1.21 0.16 99.82
107 INT141762 Nfkb1 Regulation of Positive_regulation of PECAM1 1 0.01 1.21 0.16 99.82
108 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37 99.80
109 INT265877 IGF1 Regulation of Binding of GH1 and IGF1 1 0.03 0.47 0.07 99.80
110 INT187290 Binding of HEY1 and Gtf3a 1 0.00 6.18 0.83 99.78
111 INT310202 Binding of RS1 and SNRNP70 1 0.05 1.77 0 99.76
112 INT348723 ED Positive_regulation of PTEN 1 0.04 1.3 0 99.76
113 INT260392 Hmox1 Positive_regulation of Adipoq 1 0.32 0.65 0.07 99.76
114 INT317602 Binding of TNC and PAH 1 0.02 1.74 0 99.72
115 INT245832 VEGFA Positive_regulation of Phosphorylation of Ocln 1 0.04 1.61 0 99.72
116 INT172837 ROS1 Positive_regulation of Nfkb1 1 0.00 2.11 0.16 99.72
117 INT81735 Binding of Ins1 and Pomc 1 0.20 2.24 0.71 99.70
118 INT255164 Regulation of PM20D2 Regulation of FLNA 1 0.00 0.82 0 99.70
119 INT255165 PM20D2 Regulation of FLNA 1 0.00 0.76 0 99.70
120 INT245824 Plg Regulation of Negative_regulation of Ocln 1 0.06 0.57 0 99.68
121 INT168941 Irs2 Regulation of Gene_expression of Igf1r 1 0.39 0.91 0.16 99.68
122 INT172829 Binding of Nfkb1 and ISYNA1 1 0.00 2.06 0.17 99.68
123 INT57586 Tbxa2r Regulation of Positive_regulation of Uae1 1 0.08 0.52 0.13 99.68
124 INT178967 Slc7a2 Regulation of Localization of Ins1 1 0.01 0.32 0 99.68
125 INT241026 Agtrap Positive_regulation of Mapk1 1 0.37 0.19 0 99.68
126 INT267155 Binding of INS and SUGT1 1 0.02 0.81 0.04 99.66
127 INT204173 Binding of Cs and Nox1 1 0.07 1 0.04 99.64
128 INT241030 Agtr2 Positive_regulation of Phosphorylation of Mapk1 1 0.06 0.19 0 99.64
129 INT245835 Plg Negative_regulation of Gene_expression of VEGFA 1 0.05 3.51 0 99.62
130 INT245822 Plg Negative_regulation of Phosphorylation of Mapk3 1 0.10 2.09 0 99.62
131 INT184542 Positive_regulation of Ccl2 Positive_regulation of Gpbar1 1 0.10 1.39 0.09 99.62
132 INT184539 Spp1 Positive_regulation of Gpbar1 1 0.03 1.37 0.09 99.62
133 INT184541 Ccl2 Positive_regulation of Gpbar1 1 0.10 1.37 0.09 99.62
134 INT238805 Binding of DSP and HSPB2 1 0.09 4.2 0.13 99.56
135 INT314867 Binding of Cdc7 and Cdkn2b 1 0.25 1.16 0.14 99.56
136 INT314859 Binding of Cdkn2b and Tgfbr3 1 0.33 1.16 0.14 99.56
137 INT184538 Positive_regulation of Ccl2 Positive_regulation of Spp1 1 0.34 1.38 0.09 99.54
138 INT184537 Ccl2 Positive_regulation of Spp1 1 0.34 1.37 0.09 99.54
139 INT230853 Binding of SELE and VWF 1 0.06 1.3 0.07 99.52
140 INT314774 Binding of Gast and Glp1r 1 0.01 0.62 0 99.52
141 INT51720 Negative_regulation of Ins1 Negative_regulation of Igf1 1 0.12 0.85 0.11 99.52
142 INT267152 Binding of LEP and DDX12P 1 0.00 0.69 0.05 99.52
143 INT267153 Binding of LEP and SUGT1 1 0.02 0.69 0.05 99.52
144 INT234793 RAB27A Positive_regulation of Localization of INS 1 0.03 1.26 0 99.52
145 INT344397 Binding of Crp and Ucp2 1 0.37 0.46 0 99.50
146 INT262635 Binding of HLA-DQA1 and HLA-DRA 1 0.05 0.53 0 99.48
147 INT352517 Binding of INS and Adipoq 1 0.09 1.32 0.07 99.48
148 INT245821 Binding of Ppp2r2b and Ocln 1 0.00 0.81 0 99.44
149 INT221402 Binding of INS and LPA 1 0.00 0.63 0 99.44
150 INT245834 Plg Regulation of Gene_expression of VEGFA 1 0.04 1.11 0 99.42
151 INT190683 Binding of A2M and INS 4 0.11 4.97 0.32 99.36
152 INT160985 Urb1 Negative_regulation of Negative_regulation of Faah 1 0.41 1.36 0.74 99.32
153 INT329219 Ins1 Positive_regulation of Gene_expression of Slc2a4 1 0.04 0.93 0.05 99.32
154 INT253136 Binding of Il6 and Ins1 1 0.11 0.6 0.03 99.32
155 INT338839 Negative_regulation of Binding of Cat and Tnnc1 1 0.04 1.78 0 99.28
156 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6 99.28
157 INT257870 Agt Positive_regulation of Akt1 2 0.18 1.5 0.09 99.28
158 INT314856 Binding of Cdc7 and Cdkn2a 1 0.28 1.34 0.14 99.28
159 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14 99.28
160 INT242204 DPP4 Positive_regulation of Gene_expression of GLP1R 1 0.03 0.66 0.1 99.26
161 INT355438 Gene_expression of Pdia3 Negative_regulation of Gene_expression of Ddit3 1 0.05 4.79 0.06 99.24
162 INT188789 Binding of pad and Mthfr 1 0.06 4.6 0.31 99.24
163 INT355445 Gene_expression of Pdia3 Negative_regulation of Gene_expression of TNF 1 0.00 1.31 0 99.24
164 INT113723 Gip Regulation of MIA3 2 0.00 1.28 0.08 99.24
165 INT164925 GIP Positive_regulation of Localization of INS 2 0.59 0.86 0.09 99.24
166 INT65644 Binding of AFA and Dbp 1 0.10 0.86 0.1 99.24
167 INT31307 Ghrh Regulation of Gh1 3 0.27 1.36 0.7 99.22
168 INT133854 Mcc Positive_regulation of Ngf 1 0.00 0.9 0.56 99.20
169 INT240942 Ins1 Regulation of Transcription of Pck1 1 0.08 0.73 0 99.20
170 INT245830 VEGFA Regulation of Ocln 1 0.02 0.83 0 99.20
171 INT343911 Mthfd1 Positive_regulation of Gene_expression of IL12A 1 0.00 0.41 0.23 99.20
172 INT172827 ROS1 Positive_regulation of Tnf 1 0.01 2.1 0.16 99.16
173 INT7367 Ghrh Regulation of Localization of Gh1 5 0.49 1.55 2.25 99.14
174 INT31306 Ghrh Regulation of Localization of Gnrhr 2 0.14 1 0.73 99.14
175 INT280052 Negative_regulation of Dpp4 Positive_regulation of Zglp1 1 0.03 0.72 0.18 99.14
176 INT230745 Negative_regulation of Ace Negative_regulation of Icam1 1 0.05 1.22 0.29 99.14
177 INT101443 Penk Positive_regulation of Localization of Gcg 1 0.50 1.21 1.04 99.12
178 INT101442 Penk Positive_regulation of Localization of Ins1 1 0.29 0.9 0.73 99.12
179 INT125769 GLP1R Regulation of INS 1 0.44 0.7 0 99.12
180 INT355447 Gene_expression of Pdia3 Negative_regulation of Transcription of TNF 1 0.00 1.8 0.06 99.12
181 INT355433 Gene_expression of Pdia3 Negative_regulation of Transcription of Ddit3 1 0.03 1.79 0.06 99.12
182 INT314772 Binding of Egf and Gast 1 0.02 0.62 0 99.12
183 INT4381 RIPK2 Positive_regulation of Localization of INS 1 0.13 0.53 0.34 99.12
184 INT123923 asa Positive_regulation of Il10 1 0.04 1.97 0.19 99.08
185 INT182774 Binding of ETV3 and SAE1 1 0.00 1.17 0 99.08
186 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82 99.08
187 INT258492 Binding of Ins1 and Cdipt 1 0.00 0.92 0 99.08
188 INT141911 Arih2 Regulation of Positive_regulation of Cpox 1 0.01 1.19 0.76 99.04
189 INT141910 Arih2 Regulation of Cpox 1 0.01 1.19 0.76 99.04
190 INT185162 Binding of CRP and Retn 1 0.13 2.8 0.12 99.00
191 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82 99.00
192 INT291199 Binding of VEGFA and Angpt1 1 0.08 0.69 0 99.00
193 INT284091 VWF Negative_regulation of PON2 1 0.41 2.32 0 99.00
194 INT284090 VWF Negative_regulation of SERPINA1 1 0.04 2.34 0 99.00
195 INT284093 VWF Negative_regulation of APOE 1 0.40 2.32 0 99.00
196 INT246136 Binding of Ins1 and Capn10 1 0.14 0.86 0.03 99.00
197 INT238870 INS Positive_regulation of Gene_expression of GCG 1 0.39 1.06 0 99.00
198 INT31641 POMC Regulation of Gene_expression of INS 1 0.26 0.25 0.15 99.00
199 INT284094 VWF Negative_regulation of CNDP2 1 0.14 1.16 0 99.00
200 INT153424 Pomc Positive_regulation of Transcription of Qrfp 1 0.02 0.23 0.26 99.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Diabetes Mellitus. They are ordered first by their pain relevance and then by number of times they were reported in Diabetes Mellitus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 100.00
2 INT812 Localization of INS 1026 0.81 515.6 145.31 100.00
3 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 100.00
4 INT1114 Localization of Ins1 748 0.80 192.95 165.48 100.00
5 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 100.00
6 INT224366 Gene_expression of Ager 111 0.77 125.37 8.49 100.00
7 INT251 Regulation of INS 398 0.62 232.47 55.04 100.00
8 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14 100.00
9 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 100.00
10 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 100.00
11 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 100.00
12 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 100.00
13 INT14572 Binding of INS 205 0.48 175.43 13.38 100.00
14 INT2276 Regulation of Ins1 234 0.61 103.78 54.05 100.00
15 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 100.00
16 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 100.00
17 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 100.00
18 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 100.00
19 INT2275 Negative_regulation of Localization of Ins1 183 0.59 51.02 44.94 100.00
20 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53 100.00
21 INT123466 Binding of T2dm2 21 0.37 34.87 2.91 100.00
22 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46 100.00
23 INT95272 Regulation of Gene_expression of Edn1 19 0.53 17.85 3.42 100.00
24 INT95321 Localization of Hcrtr1 4 0.79 14.81 1.66 100.00
25 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 100.00
26 INT100861 Binding of CRP 179 0.48 175.2 26.45 100.00
27 INT20266 Positive_regulation of Bdkrb1 60 0.69 63.64 56.59 100.00
28 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 100.00
29 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 100.00
30 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27 100.00
31 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 100.00
32 INT224369 Binding of Ager 43 0.42 40.57 3.86 100.00
33 INT224367 Negative_regulation of Ager 15 0.46 25.57 0.78 100.00
34 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 100.00
35 INT17086 Binding of HSD11B1 84 0.47 122.28 6.16 100.00
36 INT93350 Binding of Lepr 17 0.05 27.21 1.5 100.00
37 INT26492 Negative_regulation of Localization of GCG 73 0.58 22.2 9.48 100.00
38 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04 100.00
39 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 100.00
40 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 100.00
41 INT73602 Positive_regulation of Ager 35 0.69 30.66 3.74 100.00
42 INT2578 Binding of Ins1 74 0.48 33.57 12.92 100.00
43 INT185152 Positive_regulation of T2dm2 7 0.17 14.93 0.46 100.00
44 INT146300 Binding of RS1 31 0.22 29.55 3.04 100.00
45 INT191926 Negative_regulation of Lepr 13 0.48 17.68 0.8 100.00
46 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 100.00
47 INT185156 Gene_expression of T2dm2 9 0.45 10.44 0.56 100.00
48 INT56494 Localization of Ide 73 0.68 22.9 11.26 100.00
49 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 100.00
50 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 100.00
51 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 100.00
52 INT17913 Regulation of HSD11B1 87 0.60 93.23 6.04 100.00
53 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38 100.00
54 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 100.00
55 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 100.00
56 INT122902 Positive_regulation of Gene_expression of Spp1 54 0.70 56.3 6.33 100.00
57 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 100.00
58 INT60749 Localization of IAPP 17 0.78 12.57 1.69 100.00
59 INT224370 Localization of Ager 7 0.65 11.64 0.3 100.00
60 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 100.00
61 INT224368 Negative_regulation of Gene_expression of Ager 8 0.39 13.94 1.03 100.00
62 INT14681 Negative_regulation of GCG 31 0.57 13.55 4.98 100.00
63 INT170557 Gene_expression of Lepr 16 0.67 17.26 2.78 100.00
64 INT1224 Gene_expression of Fabp6 34 0.64 23.69 9.08 100.00
65 INT17626 Positive_regulation of Localization of GCG 36 0.69 13.94 4.06 100.00
66 INT148 Positive_regulation of Gnrhr 182 0.70 47.44 79.64 100.00
67 INT56385 Positive_regulation of Gk 11 0.22 15.07 1.28 100.00
68 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 100.00
69 INT38366 Regulation of Cat 45 0.62 23.45 5.34 100.00
70 INT69485 Regulation of Bcl2a1c 14 0.34 9.99 0.13 100.00
71 INT90937 Negative_regulation of Gene_expression of Trpv1 34 0.59 22.74 18.12 100.00
72 INT31989 Binding of SOD1 43 0.47 19.38 2.55 100.00
73 INT61864 Regulation of Gene_expression of Gria1 24 0.62 13.27 14.3 100.00
74 INT6481 Binding of TNF 624 0.48 510.2 214.82 100.00
75 INT121834 Gene_expression of IAPP 24 0.66 20.96 0.26 100.00
76 INT184549 Positive_regulation of Gpbar1 1 0.13 10.35 0.19 100.00
77 INT170482 Regulation of Gene_expression of Mapk1 5 0.43 5.73 2.1 100.00
78 INT12865 Positive_regulation of U 7 0.50 5.13 5.29 100.00
79 INT22907 Positive_regulation of Ggt1 33 0.67 17.82 5.28 100.00
80 INT10056 Positive_regulation of Fabp6 77 0.59 36.99 16.8 100.00
81 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01 100.00
82 INT7105 Gene_expression of pad 54 0.77 63.68 8.8 100.00
83 INT28834 Positive_regulation of Bdkrb1 38 0.69 30.48 26.89 100.00
84 INT18845 Regulation of IAPP 11 0.60 9 1.81 100.00
85 INT240999 Negative_regulation of Sypl 5 0.06 4.09 0.2 100.00
86 INT173208 Binding of CNBP 9 0.25 11.01 1.23 100.00
87 INT28020 Binding of Adipoq 10 0.36 11.49 0.77 100.00
88 INT240788 Gene_expression of Bcl2a1c 8 0.37 7.35 0.03 100.00
89 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37 100.00
90 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
91 INT158409 Gene_expression of T2DM 3 0.65 9.58 0.56 100.00
92 INT238798 Negative_regulation of Gene_expression of Tmc1 1 0.05 7.99 0 100.00
93 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47 100.00
94 INT1032 Regulation of Ca2 202 0.52 54.91 53.03 100.00
95 INT238786 Positive_regulation of Binding of Ager 1 0.40 6.84 0 100.00
96 INT176521 Positive_regulation of Lepr 8 0.07 6.6 0.03 100.00
97 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 100.00
98 INT108252 Positive_regulation of Renbp 16 0.24 11.66 1.68 100.00
99 INT40160 Positive_regulation of Adora1 74 0.70 26.36 33.03 100.00
100 INT238791 Localization of Tmc1 1 0.09 6.07 0 100.00
101 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 100.00
102 INT178024 Negative_regulation of Negative_regulation of Bdnf 6 0.37 5.31 0.99 100.00
103 INT280039 Negative_regulation of T2dm2 3 0.02 4 0.07 100.00
104 INT164010 Gene_expression of CNBP 7 0.53 9.13 1.71 100.00
105 INT255568 Positive_regulation of Gene_expression of Gk 4 0.17 8.23 0.11 100.00
106 INT102698 Binding of ACCS 54 0.42 66.73 9.06 100.00
107 INT22454 Regulation of Crp 213 0.62 160.67 49.24 100.00
108 INT130633 Negative_regulation of Gene_expression of Pck1 6 0.37 3.19 2.48 100.00
109 INT101883 Regulation of Gene_expression of Nos3 11 0.52 6.71 2.73 100.00
110 INT47451 Positive_regulation of Positive_regulation of ras 18 0.35 10.07 4.6 100.00
111 INT140991 Negative_regulation of Stat3 15 0.53 7.55 2.04 100.00
112 INT49001 Regulation of Gria1 51 0.56 18.28 31.22 100.00
113 INT242211 Negative_regulation of GLP1R 9 0.36 3.4 0.26 100.00
114 INT101542 Positive_regulation of RRAD 6 0.44 5.34 0.42 100.00
115 INT1087 Negative_regulation of Msr1 32 0.57 8.35 10.72 100.00
116 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04 100.00
117 INT79928 Positive_regulation of Localization of ALB 10 0.60 8.96 1.05 100.00
118 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 100.00
119 INT34669 Localization of Hypism 8 0.25 10.79 1.2 100.00
120 INT178332 Regulation of SUGT1 4 0.05 3.88 0 100.00
121 INT67078 Binding of Ifng 7 0.48 4.84 2.73 100.00
122 INT154603 Negative_regulation of Localization of Hypism 3 0.08 6.44 0.77 100.00
123 INT176528 Regulation of Spp1 9 0.45 9.05 0.77 100.00
124 INT81291 Regulation of Gene_expression of Hmox1 11 0.60 8.78 2.46 100.00
125 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 100.00
126 INT2085 Positive_regulation of LH 441 0.70 60.15 191.02 100.00
127 INT184551 Gene_expression of Gpbar1 1 0.14 5.59 0 100.00
128 INT97777 Positive_regulation of CNBP 7 0.37 9.85 1.09 100.00
129 INT49087 Positive_regulation of Rab38 20 0.00 8.01 12 100.00
130 INT49197 Binding of SELE 7 0.41 7.95 0.74 100.00
131 INT87211 Positive_regulation of Localization of Nfkb1 27 0.59 15.84 5.25 100.00
132 INT65772 Positive_regulation of Positive_regulation of Bdkrb1 6 0.49 8.34 6.54 100.00
133 INT199078 Gene_expression of Nox4 3 0.59 3.83 0.41 100.00
134 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47 100.00
135 INT71879 Negative_regulation of Localization of Nfkb1 30 0.57 21.8 13.48 100.00
136 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67 100.00
137 INT210907 Binding of IGHD1-14 3 0.35 4.63 0.06 100.00
138 INT131019 Binding of T2DM 6 0.47 6.97 0.31 100.00
139 INT84909 Positive_regulation of SUGT1 22 0.08 22.01 5.43 100.00
140 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24 100.00
141 INT2106 Regulation of Localization of LH 279 0.62 22.37 122.77 100.00
142 INT276437 Binding of Spir1 4 0.12 6.56 0 100.00
143 INT109090 Positive_regulation of Gene_expression of Fabp6 4 0.35 3.58 0.68 100.00
144 INT224372 Regulation of Gene_expression of Ager 6 0.39 4.98 0.43 100.00
145 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38 100.00
146 INT56374 Gene_expression of AMBP 34 0.54 35.85 6.25 100.00
147 INT65211 Binding of Prkcg 38 0.48 14.75 16.92 100.00
148 INT246908 Binding of Igf2bp2 1 0.15 1.96 0 100.00
149 INT130572 Positive_regulation of Gene_expression of Flt1 2 0.46 3.24 0.13 100.00
150 INT185154 Regulation of T2dm2 2 0.02 3.23 0.08 100.00
151 INT23199 Binding of LDLR 22 0.47 17.08 1.16 100.00
152 INT57069 Regulation of Gria2 28 0.44 10.11 11.06 100.00
153 INT302547 Negative_regulation of Gene_expression of Imgt1 1 0.03 2.92 0.16 100.00
154 INT615 Regulation of Alb 66 0.62 33.43 15.33 100.00
155 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 100.00
156 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78 100.00
157 INT45065 Gene_expression of Ado 3 0.54 2.34 1.55 100.00
158 INT147082 Binding of Cdkal1 2 0.20 1.82 0 100.00
159 INT141230 Negative_regulation of Evpl 2 0.23 2.6 0.11 100.00
160 INT21606 Positive_regulation of Regulation of Ins1 8 0.41 3.9 2.97 100.00
161 INT109390 Regulation of Gene_expression of Flt1 4 0.41 4.08 0.51 100.00
162 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 100.00
163 INT4144 Gene_expression of SHBG 64 0.68 39.94 6.08 100.00
164 INT154294 Positive_regulation of Gene_expression of Nphs1 1 0.69 3.09 0.41 100.00
165 INT6826 Transcription of Pdyn 130 0.71 22.19 54.88 100.00
166 INT50080 Binding of APOE 38 0.45 29.61 2.67 100.00
167 INT147084 Binding of Slc30a8 4 0.37 1.95 0.2 100.00
168 INT228294 Binding of RRAD 2 0.00 2.55 0 100.00
169 INT147088 Gene_expression of HHEX 5 0.65 4.86 0.99 100.00
170 INT2782 Regulation of Gene_expression of Pomc 75 0.62 15.04 38.97 100.00
171 INT260581 Binding of DMPK 7 0.43 5.09 0.28 100.00
172 INT80624 Regulation of CNBP 5 0.36 3.36 0.45 100.00
173 INT94925 Regulation of Gene_expression of Grip2 7 0.55 4.23 3.18 100.00
174 INT18844 Binding of IAPP 11 0.36 11.01 1.45 100.00
175 INT243008 Positive_regulation of Gene_expression of Bcl2a1c 2 0.24 1.96 0.03 100.00
176 INT2660 Negative_regulation of Fabp6 58 0.49 33.74 18.27 100.00
177 INT77433 Regulation of Gene_expression of Nos2 49 0.62 35.07 16.33 100.00
178 INT250219 Positive_regulation of KCNJ11 3 0.68 2.5 0.12 100.00
179 INT49110 Regulation of Grip2 46 0.61 13.57 30.87 100.00
180 INT170625 Binding of SERPINA5 8 0.32 8.42 0.69 100.00
181 INT75908 Regulation of LEP 77 0.60 60.16 15.19 100.00
182 INT65352 Negative_regulation of CNBP 6 0.37 4.59 0.35 100.00
183 INT12598 Binding of DBP 20 0.48 13.11 3.62 100.00
184 INT17686 Negative_regulation of Hdl1 72 0.36 81.85 7.74 100.00
185 INT209257 Negative_regulation of SUB1 3 0.05 2.16 0.13 100.00
186 INT182788 Gene_expression of ETV3 8 0.40 11.33 0.36 100.00
187 INT83431 Binding of ADIPOQ 35 0.48 33.63 3.83 100.00
188 INT180161 Binding of Nfasc 23 0.48 10.92 2.4 100.00
189 INT291035 Regulation of Gene_expression of Ado 1 0.08 1.35 0.74 100.00
190 INT277114 Binding of FTO 3 0.34 3.93 0 100.00
191 INT214119 Regulation of Lepr 2 0.23 3.17 0.23 100.00
192 INT158408 Gene_expression of Idd3 1 0.60 2.68 0.28 100.00
193 INT6926 Regulation of Pag1 72 0.39 55.79 65.09 100.00
194 INT5649 Negative_regulation of Positive_regulation of Mpo 31 0.59 26.62 11.92 100.00
195 INT174797 Regulation of Tnfsf4 1 0.03 4.05 0.54 100.00
196 INT207818 Positive_regulation of Kcnj11 2 0.48 1.67 0.07 100.00
197 INT51622 Positive_regulation of Gene_expression of Nr2c2 4 0.18 1.71 0.81 100.00
198 INT240986 Regulation of Agtrap 4 0.45 2.21 0.88 100.00
199 INT58477 Gene_expression of Chdh 33 0.74 39.48 19.78 100.00
200 INT18345 Positive_regulation of Positive_regulation of Gnrhr 16 0.42 4.99 4.91 100.00
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