D:Diabetic Neuropathy

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Disease Term
Synonyms AMYOTROPHIES DIABETIC, Amyotrophy Diabetic, Asymmetric Diabetic Proximal Motor Neuropathy, Asymmetric Polyneuropathies Diabetic, Asymmetric Polyneuropathy Diabetic, Autonomic Neuropathies Diabetic, Autonomic Neuropathy Diabetic, Diabetes Mellitus With Neurological Manifestation, DIABETES MELLITUS WITH NEUROLOGICAL MANIFESTATION DISORDER, Diabetes Mellitus With Neuropathy, Diabetes With Neurological Manifestations
Documents 1444
Hot Single Events 200
Hot Interactions 10

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Diabetic Neuropathy. They are ordered first by their relevance to Diabetic Neuropathy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73 100.00
2 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13 98.40
3 INT314756 IL6 Positive_regulation of Gene_expression of Crp 2 0.13 4.58 0.48 95.32
4 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82 94.76
5 INT305334 Jun Positive_regulation of Gene_expression of Tcstv1 1 0.00 1.04 0.27 94.04
6 INT266408 Binding of HMGB1 and Ager 1 0.01 2.57 0.76 92.20
7 INT166625 Acer3 Positive_regulation of Trpa1 1 0.01 1.91 1 90.84
8 INT230245 Binding of CBFA2T2 and Cd2bp2 1 0.00 0.36 0.08 88.48
9 INT86997 Binding of HIVEP1 and NGF 2 0.03 1.75 1.73 84.00
10 INT266383 Binding of Ager and S100b 1 0.01 3.48 0.33 80.60
11 INT138073 Binding of TRPV1 and TUFMP1 1 0.03 0.46 0.86 76.56
12 INT314197 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.48 1.16 0.61 75.44
13 INT51720 Negative_regulation of Ins1 Negative_regulation of Igf1 1 0.12 0.85 0.11 75.00
14 INT153765 Positive_regulation of Edn1 Positive_regulation of Gtf3a 2 0.04 2.26 0.82 74.64
15 INT266375 S100b Positive_regulation of Ager 1 0.02 1.8 0.31 74.64
16 INT266405 S100b Positive_regulation of Gene_expression of TFAM 1 0.00 1.02 0.21 74.64
17 INT266401 S100b Positive_regulation of S100b Positive_regulation of Ager 1 0.01 0.96 0.21 74.64
18 INT153766 Edn1 Positive_regulation of Gtf3a 1 0.04 1.25 0.41 73.60
19 INT314214 Mapk14 Positive_regulation of Ngf 1 0.43 1.97 1.56 73.20
20 INT324926 Ptpro Positive_regulation of Bdkrb2 1 0.01 2.25 1.5 71.88
21 INT166624 Acer3 Positive_regulation of Acer3 Positive_regulation of Trpa1 1 0.00 0.78 0.37 71.80
22 INT249851 VEGFA Positive_regulation of Gene_expression of Nos3 1 0.05 0.44 0.1 69.00
23 INT249848 Fgf2 Positive_regulation of Gene_expression of Nos3 1 0.33 0.44 0.1 68.64
24 INT324927 Syt17 Positive_regulation of Bdkrb1 1 0.04 4.29 2.96 65.68
25 INT291578 Negative_regulation of Pde12 Positive_regulation of Pde5a 1 0.03 1.11 1.67 61.00
26 INT220056 Binding of NTF3 and NTRK1 1 0.07 1.12 0.78 58.96
27 INT220063 Binding of NTF3 and NTRK2 1 0.09 1.13 0.78 58.96
28 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18 58.56
29 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67 57.84
30 INT220057 Binding of NTS and TNFRSF1B 1 0.08 1.23 0.76 57.28
31 INT326575 Nrg1 Positive_regulation of Gene_expression of JUN 1 0.38 0.86 0.2 52.24
32 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15 52.08
33 INT249849 Ufm1 Positive_regulation of Fgf2 1 0.01 0.56 0.14 50.00
34 INT249852 Ufm1 Positive_regulation of VEGFA 1 0.00 0.55 0.14 50.00
35 INT312841 Pou3f1 Regulation of Gene_expression of Plp1 1 0.24 0.16 0.09 50.00
36 INT312839 Egr2 Regulation of Gene_expression of Mbp 1 0.32 0.16 0.09 50.00
37 INT312843 Egr2 Regulation of Gene_expression of Plp1 1 0.31 0.16 0.09 50.00
38 INT312840 Egr2 Regulation of Gene_expression of Mag 1 0.31 0.16 0.09 50.00
39 INT312844 Pou3f1 Regulation of Gene_expression of Pmp22 1 0.27 0.16 0.09 50.00
40 INT312842 Pou3f1 Regulation of Gene_expression of Mag 1 0.24 0.16 0.09 50.00
41 INT312846 Egr2 Regulation of Gene_expression of Pmp22 1 0.35 0.16 0.09 50.00
42 INT312845 Pou3f1 Regulation of Gene_expression of Mbp 1 0.25 0.16 0.09 50.00
43 INT249850 Binding of Ptprc and Cd34 1 0.13 0.48 0 50.00
44 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23 46.72
45 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3 46.72
46 INT314208 Trap1 Positive_regulation of Mapk14 1 0.10 0.66 0.57 45.08
47 INT310700 PGR Regulation of Gene_expression of RPLP0 1 0.01 0.37 0.25 44.04
48 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26 37.72
49 INT310711 Binding of RPLP0 and Gabrg1 1 0.04 0.37 0.45 29.60
50 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43 27.36
51 INT262618 Binding of SOAT1 and Kras 1 0.00 0.81 0.12 26.48
52 INT310701 RPLP0 Regulation of Positive_regulation of PGR 1 0.01 0.49 0.53 21.68
53 INT310712 Gabrg1 Positive_regulation of Gene_expression of PMP22 1 0.35 0.56 0.61 19.84
54 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25 16.52
55 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
56 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 5.00
57 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1 5.00
58 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
59 INT211694 Binding of Cntnap1 and Nav1 1 0.04 0 3.14 5.00
60 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81 5.00
61 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69 5.00
62 INT284860 Binding of Pdzd2 and Nav1 9 0.29 2.33 2.34 5.00
63 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28 5.00
64 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84 5.00
65 INT266391 Binding of Ager and S100a1 1 0.01 5.63 1.69 5.00
66 INT142437 Urb1 Negative_regulation of Faah 3 0.41 2.12 1.66 5.00
67 INT195930 OPRM1 Regulation of Prkaca 1 0.01 0 1.59 5.00
68 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57 5.00
69 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55 5.00
70 INT208991 Binding of CALM1 and Ca2 10 0.06 1.34 1.55 5.00
71 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54 5.00
72 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48 5.00
73 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48 5.00
74 INT291583 GUCY2C Regulation of Pde5a 1 0.00 1.12 1.45 5.00
75 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42 5.00
76 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39 5.00
77 INT314213 Mapk14 Positive_regulation of Agtrap 1 0.04 1.15 1.34 5.00
78 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32 5.00
79 INT261841 Mastl Positive_regulation of Trpa1 1 0.00 0.82 1.3 5.00
80 INT314211 Ngf Positive_regulation of Gene_expression of Agtrap 1 0.04 1.15 1.3 5.00
81 INT330124 Positive_regulation of Bdkrb1 Positive_regulation of RT1-O2-ps 1 0.02 1.97 1.3 5.00
82 INT208990 Binding of CALM1 and Trpv1 1 0.10 0.07 1.29 5.00
83 INT195929 Binding of OPRM1 and Prkaca 1 0.02 0.33 1.27 5.00
84 INT314209 Ngf Positive_regulation of Binding of Mapk14 1 0.43 1.48 1.27 5.00
85 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 0.48 1.09 1.24 5.00
86 INT314212 Mapk14 Positive_regulation of Gene_expression of Agtrap 1 0.06 1.09 1.24 5.00
87 INT195926 Prkaca Positive_regulation of Trpv1 1 0.10 0.44 1.24 5.00
88 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18 5.00
89 INT308172 Rvm Positive_regulation of Phosphorylation of GRIN1 1 0.50 0.68 1.14 5.00
90 INT308173 Binding of DRG1 and Tnfrsf1b 1 0.01 1.64 1.1 5.00
91 INT193328 Grid1 Regulation of Positive_regulation of Prkcg 1 0.00 0.1 1.1 5.00
92 INT219279 Ctss Positive_regulation of Gene_expression of Fam64a 1 0.06 1.39 0.96 5.00
93 INT219273 Fam64a Positive_regulation of Gene_expression of Ctss 1 0.06 1.39 0.96 5.00
94 INT308169 Negative_regulation of Mapk14 Negative_regulation of Ltp 1 0.01 0.79 0.95 5.00
95 INT195927 Binding of Prkaca and Trpv1 1 0.07 0.28 0.92 5.00
96 INT314207 Ngf Negative_regulation of Phosphorylation of Mapk14 1 0.33 0.4 0.88 5.00
97 INT284855 Binding of S100a10 and Nav1 4 0.21 0.99 0.88 5.00
98 INT265566 Binding of PDE4D and PTPN5 1 0.03 0.81 0.85 5.00
99 INT291581 Pde5a Regulation of Localization of Abat 1 0.03 0 0.83 5.00
100 INT261834 Itpr3 Positive_regulation of Prkca 2 0.01 0.33 0.78 5.00
101 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75 5.00
102 INT160985 Urb1 Negative_regulation of Negative_regulation of Faah 1 0.41 1.36 0.74 5.00
103 INT219274 Binding of Cx3cr1 and Cx3cl1 1 0.17 1.08 0.74 5.00
104 INT208978 Ca2 Positive_regulation of Trpv1 1 0.22 0.29 0.71 5.00
105 INT261845 NGF Positive_regulation of Trpa1 1 0.04 0.73 0.71 5.00
106 INT308167 Binding of Eln and Tnfrsf1b 1 0.01 0.94 0.71 5.00
107 INT165583 Binding of Bdnf and Ngf 3 0.33 0.81 0.69 5.00
108 INT209250 TRPV1 Positive_regulation of Localization of DRGX 1 0.06 0.82 0.68 5.00
109 INT110835 Binding of SPTLC2 and SPTLC1 2 0.42 1.36 0.68 5.00
110 INT261835 Camk2a Positive_regulation of Prkca 1 0.01 0.32 0.66 5.00
111 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65 5.00
112 INT259088 Trpv1 Positive_regulation of Calca 1 0.32 1.02 0.65 5.00
113 INT261832 Trpv1 Negative_regulation of Trpa1 1 0.10 0.58 0.64 5.00
114 INT261830 Hspg2 Negative_regulation of Trpa1 1 0.01 0.58 0.63 5.00
115 INT181084 Binding of S100a8 and S100a9 6 0.42 2.91 0.62 5.00
116 INT219277 Mapkapk2 Positive_regulation of Pla2g1b 1 0.03 0.46 0.61 5.00
117 INT219278 Mapkapk2 Positive_regulation of Pla2g2a 1 0.05 0.46 0.61 5.00
118 INT219280 Mapk14 Positive_regulation of Pla2g2a 1 0.33 0.46 0.61 5.00
119 INT324065 Ptger2 Positive_regulation of Prkaca 2 0.24 0.63 0.61 5.00
120 INT308175 Negative_regulation of Mapk14 Negative_regulation of Localization of TNF 1 0.03 0.89 0.61 5.00
121 INT219282 Mapk14 Positive_regulation of Pla2g1b 1 0.18 0.46 0.61 5.00
122 INT291579 Pde12 Regulation of Binding of Pde5a 1 0.02 0.41 0.6 5.00
123 INT324925 Ros1 Positive_regulation of Bdkrb1 1 0.08 0.67 0.6 5.00
124 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58 5.00
125 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56 5.00
126 INT266381 Positive_regulation of Ager Positive_regulation of Nfkb1 1 0.00 0.77 0.55 5.00
127 INT266376 Binding of Ager and Itgam 1 0.00 2.31 0.54 5.00
128 INT208984 Binding of Ca2 and Fig4 1 0.02 0 0.54 5.00
129 INT342689 Ptger4 Positive_regulation of Prkaca 1 0.03 0.24 0.51 5.00
130 INT308656 Pik3r1 Positive_regulation of Nos3 1 0.02 1.8 0.5 5.00
131 INT291580 Pde5a Regulation of Abat 1 0.04 0.39 0.48 5.00
132 INT342693 Binding of Prkaca and Gopc 1 0.01 0.23 0.48 5.00
133 INT314200 Positive_regulation of Binding of Nos2 and Tnf 1 0.42 0.34 0.46 5.00
134 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46 5.00
135 INT308170 Binding of thd and Tnfrsf14 1 0.00 1.84 0.46 5.00
136 INT314201 Binding of Nos2 and Tnf 1 0.31 0.33 0.46 5.00
137 INT308171 Binding of TNF and thd 1 0.00 1.84 0.45 5.00
138 INT261839 Binding of Car2 and Trpv1 1 0.03 0 0.45 5.00
139 INT285725 Binding of IGF1R and INS 1 0.27 0.07 0.4 5.00
140 INT266393 Binding of Ager and Fn1 1 0.00 0.82 0.39 5.00
141 INT266382 Binding of Col4a1 and Fn1 1 0.00 0.82 0.39 5.00
142 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39 5.00
143 INT266397 Binding of Ager and Col4a1 1 0.00 0.81 0.38 5.00
144 INT330120 Bdkrb2 Regulation of Bdkrb1 1 0.19 1.26 0.38 5.00
145 INT266419 HMGB1 Positive_regulation of Ager 1 0.01 1.37 0.37 5.00
146 INT110834 Binding of AGXT and SPTLC2 2 0.27 0.71 0.36 5.00
147 INT308653 Proc Regulation of Gene_expression of Mapk8 1 0.00 1.48 0.36 5.00
148 INT342687 Pdzd2 Regulation of Gene_expression of Nav1 1 0.19 0.3 0.35 5.00
149 INT266402 Binding of S100P and Ager 1 0.00 2.25 0.35 5.00
150 INT330122 Agt Positive_regulation of Gene_expression of Agtr1a 1 0.03 0.69 0.34 5.00
151 INT342691 Pdzd2 Regulation of Nav1 1 0.19 0.48 0.34 5.00
152 INT330121 Agtr1a Positive_regulation of Gene_expression of Bdkrb1 1 0.05 0.68 0.34 5.00
153 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34 5.00
154 INT330119 Agt Positive_regulation of Gene_expression of Bdkrb1 1 0.37 0.63 0.34 5.00
155 INT330377 Positive_regulation of Binding of TLR2 and TLR9 1 0.09 2.79 0.32 5.00
156 INT330381 Binding of TLR2 and TLR9 1 0.07 2.77 0.32 5.00
157 INT308667 Binding of Chrm1 and Positive_regulation of Binding of App 1 0.04 1.14 0.32 5.00
158 INT330389 Positive_regulation of Binding of TLR2 and TLR8 1 0.08 2.78 0.32 5.00
159 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31 5.00
160 INT330383 Binding of TLR2 and TLR3 1 0.07 2.77 0.31 5.00
161 INT330378 Positive_regulation of Binding of TLR2 and TLR3 1 0.10 2.78 0.31 5.00
162 INT330387 Binding of TLR2 and TLR8 1 0.06 2.77 0.31 5.00
163 INT229785 Binding of RAB7A and SPTLC1 1 0.40 1.5 0.27 5.00
164 INT308661 Akt1 Positive_regulation of Chuk 1 0.02 0.6 0.25 5.00
165 INT266421 Binding of HMGB1 and Il1 1 0.02 0.37 0.24 5.00
166 INT261842 Pla2g6 Positive_regulation of Trpm8 1 0.03 0 0.23 5.00
167 INT308670 Positive_regulation of CYBB Positive_regulation of Gene_expression of Ros1 1 0.00 0.68 0.23 5.00
168 INT266418 Binding of HMGB1 and Tlr4 1 0.09 0.37 0.23 5.00
169 INT238802 Binding of Ager and Renbp 6 0.02 6.46 0.22 5.00
170 INT273024 Binding of FXYD1 and RLS 1 0.04 1.24 0.21 5.00
171 INT228457 Negative_regulation of Ins1 Positive_regulation of Gene_expression of Trpv1 1 0.05 1.01 0.21 5.00
172 INT308650 Binding of nt and Ntrk2 1 0.01 0.41 0.21 5.00
173 INT266380 Binding of Tlr2 and Il1 1 0.01 0.76 0.21 5.00
174 INT330382 IFNA1 Positive_regulation of Gene_expression of IL10 1 0.06 0.83 0.21 5.00
175 INT308654 Binding of Ngfr and Nts 1 0.06 0.39 0.21 5.00
176 INT266423 Binding of HMGB1 and Mapk3 1 0.04 0.9 0.2 5.00
177 INT266410 Binding of HMGB1 and Mapk14 1 0.03 0.91 0.2 5.00
178 INT266416 Binding of HMGB1 and Mapk1 1 0.06 0.9 0.2 5.00
179 INT308645 Binding of Esr1 and Itpr3 1 0.00 0 0.2 5.00
180 INT266414 Binding of HMGB1 and Mapk8 1 0.03 0.91 0.2 5.00
181 INT266404 Binding of HMGB1 and Thbd 1 0.06 0.3 0.2 5.00
182 INT330371 Binding of TLR3 and Ifx 1 0.17 1.12 0.2 5.00
183 INT308646 Car2 Regulation of Gene_expression of Ins1 1 0.00 0 0.19 5.00
184 INT308669 CREB1 Regulation of Gene_expression of Ins1 1 0.01 0 0.19 5.00
185 INT308657 Creb1 Regulation of Gene_expression of Ins1 1 0.01 0 0.19 5.00
186 INT299370 Binding of Mapk8 and Life1 1 0.04 0.73 0.18 5.00
187 INT305335 Olfr927-ps1 Negative_regulation of Akr1b3 1 0.02 1.6 0.17 5.00
188 INT266417 Binding of TGM2 and S100a11 1 0.01 0.86 0.16 5.00
189 INT266422 HMGB1 Positive_regulation of Binding of Ager 1 0.01 0.92 0.16 5.00
190 INT330388 Binding of PTPRC and TLR2 1 0.00 1.19 0.16 5.00
191 INT266412 Binding of S100A12 and Ager 1 0.01 1.03 0.15 5.00
192 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15 5.00
193 INT270655 Adipoq Positive_regulation of IL8 Positive_regulation of Adipoq 1 0.00 1.19 0.15 5.00
194 INT342688 Binding of Cap1 and Nav1 1 0.00 0.19 0.14 5.00
195 INT266413 Positive_regulation of Binding of HMGB1 and Col4a1 1 0.02 1.05 0.14 5.00
196 INT266411 Binding of HMGB1 and Col4a1 1 0.01 1.05 0.14 5.00
197 INT252575 Rpe Negative_regulation of SOD1 1 0.03 2.39 0.14 5.00
198 INT252571 Rpe Positive_regulation of Positive_regulation of Sdcbp 1 0.04 2.27 0.13 5.00
199 INT238805 Binding of DSP and HSPB2 1 0.09 4.2 0.13 5.00
200 INT252573 Rpe Negative_regulation of Gpx1 1 0.07 2.34 0.13 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Diabetic Neuropathy. They are ordered first by their pain relevance and then by number of times they were reported in Diabetic Neuropathy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT65211 Binding of Prkcg 38 0.48 14.75 16.92 100.00
2 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93 100.00
3 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02 100.00
4 INT126581 Positive_regulation of Gli3 6 0.35 1.59 2.48 100.00
5 INT140245 Binding of Gli3 3 0.36 2.65 1.46 100.00
6 INT9304 Negative_regulation of Pag1 70 0.39 51.97 64.23 100.00
7 INT50440 Negative_regulation of Pnp 5 0.36 2.14 0.66 100.00
8 INT71150 Binding of NGF 22 0.46 13.67 14.81 100.00
9 INT222029 Localization of Msc 5 0.39 1.88 0.42 100.00
10 INT307560 Gene_expression of CMM 1 0.17 0.52 0 100.00
11 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 99.98
12 INT62373 Negative_regulation of NGF 34 0.59 25.87 22.38 99.92
13 INT138639 Gene_expression of Hcn4 32 0.75 13.85 11.25 99.92
14 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47 99.88
15 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17 99.88
16 INT12476 Negative_regulation of TRPV1 124 0.59 47.95 77.98 99.86
17 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79 99.84
18 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08 99.84
19 INT19768 Negative_regulation of LAMC2 11 0.57 10.54 5.32 99.84
20 INT117601 Positive_regulation of Trpa1 174 0.70 72.41 71.9 99.84
21 INT52712 Negative_regulation of PRKCA 64 0.57 23.11 28.43 99.84
22 INT17349 Negative_regulation of Akr1b1 41 0.59 27.03 10.65 99.80
23 INT10980 Gene_expression of GYPA 40 0.78 15.32 5.51 99.80
24 INT149108 Gene_expression of SOD3 2 0.67 0.85 0.19 99.80
25 INT100655 Regulation of BDNF 51 0.60 21.49 13.14 99.80
26 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 99.80
27 INT71494 Positive_regulation of Hspa1b 14 0.67 8.5 9.19 99.76
28 INT95318 Binding of Pain1 17 0.22 21.26 20.14 99.76
29 INT6727 Positive_regulation of Ednra 27 0.64 18.75 8.71 99.76
30 INT209258 Gene_expression of SUB1 5 0.75 3.3 0.7 99.74
31 INT209254 Negative_regulation of Gene_expression of SUB1 1 0.01 1.4 0.56 99.74
32 INT9556 Negative_regulation of NAV1 47 0.59 28.49 49.33 99.74
33 INT12765 Positive_regulation of Phosphorylation of Prkcg 59 0.66 20.16 34.67 99.60
34 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 99.60
35 INT23834 Negative_regulation of AKR1B1 8 0.55 3.79 1.15 99.60
36 INT126585 Positive_regulation of Positive_regulation of PARP1 3 0.55 2.84 0.56 99.60
37 INT126584 Regulation of Positive_regulation of PARP1 1 0.24 0.78 0.49 99.60
38 INT126583 Positive_regulation of PARP1 50 0.68 41.44 7.78 99.60
39 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32 99.54
40 INT291268 Gene_expression of Atr 1 0.06 1.48 0.57 99.54
41 INT151111 Gene_expression of Pain1 33 0.40 33.6 30.73 99.52
42 INT21793 Positive_regulation of Ngf 154 0.70 94.78 85.27 99.48
43 INT74688 Regulation of Nos1 55 0.62 22.16 25.3 99.46
44 INT20093 Binding of Akr1b1 3 0.36 0.38 0.33 99.46
45 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42 99.44
46 INT126525 Regulation of Negative_regulation of Mapk14 2 0.41 0.81 1.11 99.44
47 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45 99.42
48 INT30887 Negative_regulation of Ngf 56 0.59 32.96 20.86 99.40
49 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51 99.40
50 INT129015 Phosphorylation of Ngf 6 0.73 5.92 6.6 99.40
51 INT33127 Positive_regulation of Phosphorylation of Trib3 26 0.17 14.04 10 99.38
52 INT95738 Positive_regulation of Phosphorylation of Mapk8 40 0.70 23.46 13.88 99.38
53 INT63936 Positive_regulation of Phosphorylation of Ephb1 131 0.70 49.38 73.16 99.38
54 INT97702 Positive_regulation of Phosphorylation of Mapk14 69 0.69 49.21 36.81 99.38
55 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48 99.38
56 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61 99.38
57 INT80075 Regulation of Gene_expression of Trpv1 55 0.62 32.42 36.88 99.34
58 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71 99.32
59 INT152977 Positive_regulation of Myt1 1 0.22 1.33 0.3 99.32
60 INT107674 Negative_regulation of Parp1 7 0.27 8.91 2.88 99.32
61 INT223033 Localization of Pain1 2 0.21 1.81 1.97 99.32
62 INT6499 Localization of Ntrk2 44 0.79 11.78 8.75 99.26
63 INT12951 Negative_regulation of Cat 126 0.57 64.39 20.61 99.24
64 INT100763 Regulation of Cpa2 1 0.08 1.82 1.03 99.20
65 INT249844 Regulation of Msc 1 0.23 2.79 0.54 99.20
66 INT93281 Negative_regulation of Folh1 12 0.50 5.55 10.63 99.20
67 INT100762 Regulation of Folh1 1 0.30 1.07 0.56 99.20
68 INT33407 Negative_regulation of Naaladl1 2 0.34 0.84 0.74 99.20
69 INT66758 Binding of Nfkb1 97 0.48 50.65 23.65 99.20
70 INT97367 Gene_expression of Nav1 243 0.78 132.97 286.66 99.20
71 INT145097 Negative_regulation of Pain1 16 0.22 19.11 16.82 99.18
72 INT519 Negative_regulation of Comt 52 0.59 17.65 20.39 99.18
73 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 99.16
74 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03 99.16
75 INT63769 Regulation of Ngf 44 0.62 21.82 25.84 99.16
76 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63 99.12
77 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51 99.12
78 INT99348 Negative_regulation of PARP1 38 0.58 30.96 3.36 99.12
79 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49 99.12
80 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 99.12
81 INT42099 Regulation of AKR1B1 2 0.45 0.46 0.39 99.08
82 INT107980 Gene_expression of Mdn1 1 0.12 0.89 0.15 99.08
83 INT3180 Positive_regulation of PPY 39 0.63 25.57 10.15 99.02
84 INT73128 Regulation of Pde5a 7 0.37 4.42 4.27 99.00
85 INT50895 Regulation of GYPA 10 0.60 4.05 1.95 98.92
86 INT61084 Gene_expression of Dcp1a 5 0.10 2.68 2.47 98.92
87 INT175214 Gene_expression of HSPB2 21 0.72 22.84 0.81 98.92
88 INT97411 Transcription of Dcp1a 1 0.09 0.66 0.79 98.92
89 INT3703 Negative_regulation of Grhpr 38 0.50 11.43 9.2 98.90
90 INT55781 Regulation of Csrp1 11 0.34 6.87 3.36 98.88
91 INT103923 Negative_regulation of Positive_regulation of Mapk14 23 0.53 13.95 10.64 98.84
92 INT151906 Positive_regulation of Positive_regulation of Nfasc 2 0.11 1.98 0.98 98.84
93 INT11121 Positive_regulation of NPPA 64 0.70 34.09 11.96 98.84
94 INT15156 Positive_regulation of Localization of NPPA 21 0.70 8.61 6.97 98.84
95 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 98.80
96 INT270628 Regulation of Ucp2 2 0.41 1.33 0.1 98.80
97 INT152975 Positive_regulation of Gene_expression of Myt1 1 0.33 0.67 0.17 98.76
98 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 98.76
99 INT298013 Binding of MNS1 1 0.35 1.14 0.13 98.72
100 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14 98.68
101 INT74944 Positive_regulation of Gene_expression of HGF 31 0.70 17.69 6.68 98.68
102 INT86280 Positive_regulation of Nfasc 14 0.62 6.56 3.84 98.64
103 INT103547 Gene_expression of TRPV3 47 0.78 17.06 13.34 98.64
104 INT7132 Localization of NPPA 53 0.81 19.79 10.86 98.64
105 INT123557 Gene_expression of Atf3 9 0.78 11.21 5.26 98.60
106 INT48240 Binding of Ngf 46 0.46 23.51 24.42 98.60
107 INT123558 Positive_regulation of Gene_expression of Atf3 2 0.70 1.45 0.43 98.60
108 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 98.60
109 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66 98.60
110 INT26489 Negative_regulation of Npr1 15 0.59 5.7 6.79 98.60
111 INT123787 Gene_expression of Bid 25 0.66 16 6.35 98.60
112 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14 98.56
113 INT6110 Negative_regulation of Gene_expression of Ins1 83 0.56 60.59 16.07 98.56
114 INT22128 Positive_regulation of HIVEP1 61 0.43 70.52 6.07 98.56
115 INT20266 Positive_regulation of Bdkrb1 60 0.69 63.64 56.59 98.52
116 INT53038 Positive_regulation of Agtr1a 35 0.67 23.76 11.68 98.52
117 INT65772 Positive_regulation of Positive_regulation of Bdkrb1 6 0.49 8.34 6.54 98.52
118 INT70790 Positive_regulation of Slc14a2 4 0.18 1.36 1.16 98.52
119 INT91926 Positive_regulation of Transcription of Kcnab3 2 0.08 0.95 1.35 98.52
120 INT97417 Positive_regulation of Transcription of LOC682801 1 0.02 0.6 0.71 98.52
121 INT49436 Binding of TRPV1 145 0.48 38.35 55.08 98.52
122 INT16396 Negative_regulation of CEBPZ 76 0.48 30.03 21.6 98.52
123 INT7313 Negative_regulation of CDNF 7 0.05 2.53 2.34 98.52
124 INT152976 Binding of Myt1 1 0.18 0.6 0.16 98.40
125 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 98.36
126 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05 98.36
127 INT27954 Positive_regulation of Gene_expression of Ngf 87 0.70 57.91 51.96 98.36
128 INT48238 Regulation of Gene_expression of Ngf 25 0.62 11.48 16.42 98.36
129 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19 98.36
130 INT15326 Phosphorylation of Trib3 83 0.55 30.96 22.27 98.36
131 INT121884 Regulation of Binding of Nos1 2 0.33 1.63 2.15 98.36
132 INT49172 Regulation of Nos1 43 0.52 27.53 23.66 98.36
133 INT80251 Binding of Nos1 21 0.30 8.24 11.31 98.36
134 INT93350 Binding of Lepr 17 0.05 27.21 1.5 98.36
135 INT115200 Binding of Slc14a2 2 0.07 1.16 0.66 98.36
136 INT15744 Localization of GYPA 12 0.64 7.19 2.61 98.32
137 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 98.28
138 INT12054 Negative_regulation of MIA3 32 0.45 23.2 6.18 98.24
139 INT90937 Negative_regulation of Gene_expression of Trpv1 34 0.59 22.74 18.12 98.24
140 INT308637 Positive_regulation of Gene_expression of MANEA 1 0.67 0.59 0.19 98.22
141 INT152974 Gene_expression of Myt1 1 0.37 0.67 0.17 98.20
142 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66 98.20
143 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 98.20
144 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53 98.20
145 INT9126 Negative_regulation of Xdh 20 0.58 8.58 3.28 98.16
146 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04 98.12
147 INT99327 Negative_regulation of PNKD 3 0.57 1.24 0.56 98.12
148 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46 98.08
149 INT109316 Negative_regulation of Mapk8 72 0.59 50.59 17.24 98.04
150 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 98.04
151 INT308639 Regulation of Gene_expression of MANEA 1 0.44 0.59 0.19 98.02
152 INT103585 Gene_expression of MANEA 4 0.75 2.12 0.31 98.02
153 INT140244 Positive_regulation of Akr1b3 3 0.69 2.8 1.12 98.00
154 INT87753 Transcription of Kcnab3 8 0.55 1.7 4.85 98.00
155 INT97414 Regulation of Transcription of Kcnab3 1 0.07 0.59 0.7 98.00
156 INT151907 Binding of Ecm1 6 0.11 2.48 0.83 97.92
157 INT91931 Positive_regulation of Kcnab3 4 0.13 2.14 3.81 97.92
158 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 97.88
159 INT95207 Negative_regulation of Pde5a 46 0.58 32.01 10.14 97.84
160 INT16255 Negative_regulation of Ntf3 21 0.51 12.92 11.93 97.84
161 INT101592 Gene_expression of TRPM8 82 0.78 70.61 22.89 97.84
162 INT33667 Gene_expression of Cnga1 15 0.72 10.09 10.4 97.80
163 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 97.76
164 INT305322 Regulation of Olfr927-ps1 1 0.06 1.2 0.16 97.76
165 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 97.76
166 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7 97.76
167 INT102865 Positive_regulation of Positive_regulation of Prkca 25 0.69 8.34 9.9 97.72
168 INT85048 Regulation of NGF 19 0.62 11.61 10.5 97.70
169 INT170240 Regulation of SOD3 1 0.38 0.54 0.16 97.68
170 INT12001 Regulation of Ngf 97 0.62 54.64 76.25 97.60
171 INT8027 Regulation of Gene_expression of Ngf 34 0.62 26.32 31.16 97.60
172 INT16256 Regulation of Ntf3 15 0.49 9.75 13.07 97.60
173 INT91927 Transcription of LOC682801 6 0.07 1.47 3.93 97.60
174 INT97412 Regulation of Transcription of LOC682801 1 0.02 0.54 0.65 97.60
175 INT4715 Positive_regulation of Xdh 20 0.69 6.57 2.28 97.60
176 INT36338 Gene_expression of NRP2 29 0.67 6.47 2.4 97.52
177 INT118440 Gene_expression of TRPV4 20 0.71 7.33 6.01 97.44
178 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 97.44
179 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52 97.40
180 INT67915 Negative_regulation of Gtpbp4 18 0.33 6.31 10.17 97.40
181 INT118906 Regulation of Mapk14 21 0.44 17.95 11.63 97.36
182 INT3040 Gene_expression of MIA3 81 0.24 53.61 12.62 97.28
183 INT27955 Negative_regulation of Gene_expression of Ngf 16 0.59 10.43 10.17 97.28
184 INT89854 Regulation of Nos2 49 0.61 42.58 24.1 97.24
185 INT90942 Regulation of P2rx1 31 0.61 16.61 13.69 97.24
186 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 97.24
187 INT99336 Negative_regulation of FOLH1 30 0.57 8.83 11.53 97.24
188 INT330333 Gene_expression of Lap2 1 0.17 1.57 0.69 97.24
189 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 97.22
190 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49 97.16
191 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 97.14
192 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26 97.08
193 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41 97.02
194 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64 97.02
195 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35 97.00
196 INT3793 Regulation of CEBPZ 59 0.61 20.91 15.83 96.96
197 INT153763 Gene_expression of Mcm3 2 0.33 1.39 0.4 96.88
198 INT153764 Positive_regulation of Gene_expression of Mcm3 1 0.03 1.14 0.4 96.88
199 INT1005 Localization of Sst 385 0.81 26.31 244.56 96.84
200 INT214 Localization of AVP 370 0.81 208.51 91.09 96.82
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