D:Diffuse Axonal Injury

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Disease Term
Synonyms Axonal Injuries Diffuse, Axonal Injury Diffuse, Dai Diffuse Axonal Injury, Dais Diffuse Axonal Injury, Diffuse Axonal Injuries, Injuries Diffuse Axonal, Injury Diffuse Axonal
Documents 34
Hot Single Events 18
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Diffuse Axonal Injury. They are ordered first by their relevance to Diffuse Axonal Injury and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT202965 Binding of STC2 and BAG3 1 0.02 7.86 2.96 71.00
2 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 27.60
3 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13 19.40
4 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4 19.16
5 INT202959 Binding of BAG3 and MCRS1 1 0.11 7.46 3.14 5.00
6 INT202974 Binding of BAG3 and CPP 1 0.25 6.22 2.73 5.00
7 INT202963 Binding of STC2 and CPP 1 0.02 5.16 2.04 5.00
8 INT202958 Binding of STC2 and MCRS1 1 0.01 3.48 1.44 5.00
9 INT202960 Binding of MCRS1 and CPP 1 0.14 2.49 1.13 5.00
10 INT202968 Binding of MCRS1 and CAP1 1 0.03 2.46 1.08 5.00
11 INT202967 MCRS1 Negative_regulation of CPP 2 0.14 2.2 0.73 5.00
12 INT202962 CPP Negative_regulation of Positive_regulation of BAG3 1 0.26 1.34 0.61 5.00
13 INT202971 Binding of BAG3 and CAP1 1 0.04 1.26 0.59 5.00
14 INT202973 Binding of CAP1 and CPP 1 0.05 1.24 0.58 5.00
15 INT202970 Binding of STC2 and CAP1 1 0.00 1.25 0.58 5.00
16 INT202972 Positive_regulation of MCRS1 Negative_regulation of CPP 1 0.16 1.64 0.57 5.00
17 INT202961 MCRS1 Negative_regulation of STC2 1 0.00 1.63 0.57 5.00
18 INT202957 CPP Negative_regulation of MCRS1 1 0.14 1.53 0.51 5.00
19 INT202969 Positive_regulation of SGSM3 Positive_regulation of MCRS1 1 0.02 1.22 0.47 5.00
20 INT202964 SGSM3 Positive_regulation of MCRS1 1 0.03 1.21 0.47 5.00
21 INT316015 AIC Regulation of ERN1 1 0.08 0.1 0.05 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Diffuse Axonal Injury. They are ordered first by their pain relevance and then by number of times they were reported in Diffuse Axonal Injury. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT163133 Gene_expression of ZBP1 28 0.65 18.59 1.25 100.00
2 INT319339 Localization of ZBP1 3 0.18 3.09 0.2 100.00
3 INT355451 Regulation of Binding of ZBP1 1 0.03 0.53 0.46 100.00
4 INT355453 Binding of ZBP1 1 0.02 0.53 0.46 100.00
5 INT355452 Regulation of ZBP1 1 0.03 0.53 0.46 100.00
6 INT21793 Positive_regulation of Ngf 154 0.70 94.78 85.27 99.56
7 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 99.10
8 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 99.10
9 INT123885 Positive_regulation of Lgals3 23 0.57 24.38 6.32 98.60
10 INT162533 Regulation of Lgals3 9 0.45 6.61 1.73 98.48
11 INT20210 Localization of Ngf 69 0.79 46.22 38.57 98.26
12 INT137614 Gene_expression of Lgals3 70 0.77 66.13 12.53 98.18
13 INT162254 Regulation of BAG3 28 0.41 18.12 4.75 95.24
14 INT202983 Regulation of STC2 1 0.03 11.98 3.33 94.92
15 INT252211 Negative_regulation of Lgals3 6 0.43 4.82 0.48 92.88
16 INT176317 Transcription of CAP1 3 0.16 1.8 1.15 89.60
17 INT193582 Gene_expression of PVR 21 0.58 14 2.39 85.44
18 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 83.72
19 INT317734 Positive_regulation of Binding of Lgals3 1 0.44 0.89 0.15 79.44
20 INT182297 Positive_regulation of Phosphorylation of MAPK14 7 0.42 3.36 1.53 77.52
21 INT152308 Binding of Lgals3 13 0.40 6.39 1.44 77.44
22 INT110178 Phosphorylation of MAPK14 40 0.68 19.38 10.37 77.24
23 INT252209 Positive_regulation of Gene_expression of Lgals3 10 0.57 8.29 1.62 77.00
24 INT168640 Positive_regulation of Gene_expression of Iba1 9 0.33 8.3 4.55 77.00
25 INT292050 Positive_regulation of Iba1 4 0.25 3.17 0.84 77.00
26 INT168641 Gene_expression of Iba1 24 0.63 12.21 6.7 76.16
27 INT94545 Positive_regulation of C7orf49 37 0.69 12.91 11.19 75.04
28 INT204838 Binding of Iba1 10 0.29 1.61 0.98 70.24
29 INT252212 Negative_regulation of Gene_expression of Lgals3 5 0.43 4.82 0.88 62.16
30 INT104731 Positive_regulation of NEFL 13 0.67 9.22 1.37 61.28
31 INT37834 Negative_regulation of Positive_regulation of CPP 14 0.58 6.22 5.69 59.92
32 INT18893 Positive_regulation of CPP 81 0.69 38.03 34.33 59.92
33 INT72924 Negative_regulation of MCRS1 27 0.19 33.59 10.29 55.20
34 INT37835 Negative_regulation of CPP 61 0.51 31.34 18.57 54.88
35 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 53.24
36 INT96155 Gene_expression of Cd86 134 0.77 50.56 17.13 53.24
37 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 51.76
38 INT24989 Positive_regulation of Cfp 125 0.61 29.55 64.9 50.80
39 INT94055 Gene_expression of Arg1 22 0.68 20.81 6.13 49.16
40 INT32905 Gene_expression of Mrc1 18 0.58 11.07 3.54 49.16
41 INT93309 Positive_regulation of CAP1 17 0.43 11.4 9.13 45.88
42 INT143612 Positive_regulation of AIC 13 0.70 2.95 6.15 34.48
43 INT15470 Regulation of CPP 42 0.48 26.1 18.25 25.20
44 INT164372 Positive_regulation of Positive_regulation of Ngfr 6 0.62 4.1 1.22 24.28
45 INT317733 Positive_regulation of Binding of Ngfr 1 0.18 0.51 0.71 24.28
46 INT48310 Binding of Ngfr 25 0.48 9.72 8.16 23.76
47 INT66038 Positive_regulation of Ngfr 32 0.69 26.07 11.75 23.28
48 INT341675 Positive_regulation of Sash3 1 0.02 1.31 0.13 20.08
49 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28 19.84
50 INT48240 Binding of Ngf 46 0.46 23.51 24.42 19.16
51 INT103463 Localization of CPP 16 0.66 9.63 4.08 13.96
52 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 5.00
53 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
54 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
55 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 5.00
56 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
57 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36 5.00
58 INT46833 Positive_regulation of SGSM3 56 0.67 24.49 30.31 5.00
59 INT48853 Positive_regulation of BDNF 82 0.69 43.92 27.99 5.00
60 INT18894 Gene_expression of CPP 44 0.77 23.05 23.05 5.00
61 INT30887 Negative_regulation of Ngf 56 0.59 32.96 20.86 5.00
62 INT184895 Gene_expression of MCRS1 46 0.42 56.03 19.44 5.00
63 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19 5.00
64 INT103469 Positive_regulation of Gene_expression of BDNF 59 0.67 24.39 18.36 5.00
65 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 5.00
66 INT180497 Binding of MRI1 45 0.42 28.35 14.77 5.00
67 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 5.00
68 INT47909 Binding of CPP 32 0.48 24.9 13.79 5.00
69 INT184890 Regulation of MCRS1 35 0.22 44.35 13.78 5.00
70 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8 5.00
71 INT10654 Negative_regulation of SGSM3 31 0.57 12.24 11.7 5.00
72 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 5.00
73 INT175554 Binding of MCRS1 21 0.23 25.2 8.59 5.00
74 INT4651 Gene_expression of Cebpz 39 0.00 20.19 8.5 5.00
75 INT162253 Gene_expression of BAG3 30 0.59 20.16 7.18 5.00
76 INT177600 Gene_expression of C7orf49 21 0.52 7.1 6.92 5.00
77 INT91217 Positive_regulation of BAG3 22 0.48 16.57 6.06 5.00
78 INT75530 Regulation of SGSM3 11 0.60 7.22 4.48 5.00
79 INT168479 Binding of BAG3 13 0.36 10.68 4.21 5.00
80 INT38859 Gene_expression of SGSM3 14 0.75 12.98 4.09 5.00
81 INT202978 Gene_expression of STC2 11 0.50 13.46 4.06 5.00
82 INT61680 Positive_regulation of PVR 23 0.60 23.27 3.86 5.00
83 INT202976 Positive_regulation of STC2 1 0.04 9.73 3.78 5.00
84 INT193281 Binding of CAP1 7 0.07 4.57 3.53 5.00
85 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52 5.00
86 INT85233 Localization of SGSM3 11 0.78 10.91 3.41 5.00
87 INT184894 Localization of MCRS1 9 0.47 10.04 3.31 5.00
88 INT202977 Binding of STC2 1 0.02 8.53 3.31 5.00
89 INT45303 Binding of SYNM 4 0.40 2.14 3.07 5.00
90 INT50080 Binding of APOE 38 0.45 29.61 2.67 5.00
91 INT123970 Negative_regulation of BAG3 11 0.38 5.29 2.6 5.00
92 INT3308 Localization of PTGER1 9 0.73 5.32 2.55 5.00
93 INT316010 Binding of AIC 3 0.42 1.47 2.4 5.00
94 INT83468 Gene_expression of ELK3 22 0.66 2.91 2.03 5.00
95 INT90177 Positive_regulation of Gene_expression of CPP 3 0.35 1.94 1.69 5.00
96 INT140858 Negative_regulation of SUGT1 9 0.05 8.41 1.4 5.00
97 INT159673 Positive_regulation of Localization of CPP 4 0.41 3.43 1.34 5.00
98 INT162467 Gene_expression of ERN1 10 0.56 5.11 1.26 5.00
99 INT23856 Regulation of Iba1 3 0.22 1.83 1.13 5.00
100 INT171433 Gene_expression of AIC 7 0.59 3.06 1.11 5.00
101 INT28929 Negative_regulation of PVR 22 0.57 16.64 1.07 5.00
102 INT202981 Positive_regulation of Binding of MCRS1 3 0.18 4.05 1.02 5.00
103 INT202979 Negative_regulation of Gene_expression of BAG3 1 0.27 1.75 0.82 5.00
104 INT162256 Positive_regulation of Binding of CPP 2 0.60 1.94 0.81 5.00
105 INT123463 Gene_expression of ATP5G3 5 0.37 2.25 0.75 5.00
106 INT156724 Positive_regulation of Positive_regulation of CPP 3 0.40 1.08 0.74 5.00
107 INT176460 Protein_catabolism of Fig4 6 0.71 3.23 0.69 5.00
108 INT189313 Localization of STC2 2 0.29 2.35 0.62 5.00
109 INT98660 Positive_regulation of Localization of SGSM3 2 0.45 1.67 0.62 5.00
110 INT202984 Negative_regulation of STC2 1 0.02 1.63 0.56 5.00
111 INT317735 Localization of Cnp 1 0.14 0.39 0.45 5.00
112 INT202980 Negative_regulation of Gene_expression of STC2 1 0.02 0.85 0.4 5.00
113 INT202975 Regulation of Regulation of STC2 1 0.01 1.08 0.36 5.00
114 INT202982 Transcription of MCRS1 1 0.25 1.19 0.33 5.00
115 INT96815 Regulation of Gene_expression of APOE 2 0.62 1.1 0.29 5.00
116 INT341674 Positive_regulation of Txnrd2 1 0.13 1.12 0.28 5.00
117 INT244537 Regulation of ERN1 3 0.26 1.32 0.25 5.00
118 INT227702 Negative_regulation of PTCRA 4 0.43 1.21 0.22 5.00
119 INT96772 Positive_regulation of Gene_expression of APOE 5 0.66 5.44 0.14 5.00
120 INT223937 Transcription of PVR 1 0.60 1.53 0.14 5.00
121 INT257559 Localization of AIC 3 0.69 1.43 0.12 5.00
122 INT244534 Negative_regulation of ERN1 2 0.25 1.08 0.09 5.00
123 INT316026 Positive_regulation of Positive_regulation of AIC 1 0.59 0.06 0.04 5.00
124 INT316028 Negative_regulation of Binding of AIC 1 0.36 0.08 0.03 5.00
125 INT316027 Regulation of Binding of AIC 1 0.39 0.09 0.03 5.00
126 INT211830 Binding of PVR 3 0.32 2.26 0.03 5.00
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