D:Diplopia

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Disease Term
Synonyms Cortical Diplopia, CORTICAL DIPLOPIAS, Diplopia Cortical, Diplopia Horizontal, DIPLOPIA INTERMITTENT, Diplopia Monocular, DIPLOPIA REFRACTIVE, DIPLOPIA UNILATERAL, Diplopia Vertical, Diplopias, Diplopias Cortical
Documents 1173
Hot Single Events 92
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Diplopia. They are ordered first by their relevance to Diplopia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT165305 CSF2 Positive_regulation of Localization of CCBE1 1 0.06 1.34 0.35 92.80
2 INT245503 SST Regulation of Gene_expression of CSF2 1 0.06 0.67 0.39 59.44
3 INT322734 Binding of CD40LG and Positive_regulation of CD40 1 0.07 0.62 0.18 32.08
4 INT322733 CD40LG Positive_regulation of Gene_expression of CD40 1 0.08 0.62 0.18 31.36
5 INT311432 Binding of TSHR and TAOK1 1 0.12 1.05 0.07 11.56
6 INT81127 Binding of Gabrd and Abat 3 0.25 0 0.96 5.00
7 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93 5.00
8 INT187361 Binding of Gabrg1 and Kcnn3 1 0.36 0.13 0.3 5.00
9 INT336946 Binding of ITGA4 and VCAM1 1 0.03 2.02 0.21 5.00
10 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
11 INT227556 Ptgds Positive_regulation of Ppara 1 0.18 0.62 0.13 5.00
12 INT220697 Binding of CHRNE and DBP 1 0.02 1.15 0.08 5.00
13 INT250153 Binding of PRNP and IKBKG 1 0.09 2.83 0.06 5.00
14 INT250150 Binding of IKBKG and SACM1L 1 0.00 2.78 0.06 5.00
15 INT220698 Binding of CHRNE and SFTPA1 1 0.01 0.75 0.06 5.00
16 INT251944 Binding of GH1 and PRNP 1 0.09 1.14 0.05 5.00
17 INT250151 Binding of GSS and MCM3 1 0.01 1.38 0.04 5.00
18 INT345060 Binding of SGCG and C2 1 0.00 0.93 0 5.00
19 INT250152 Binding of APOE and UBE4B 1 0.21 1.2 0 5.00
20 INT345059 Binding of C3 and C2 1 0.00 0 0 5.00
21 INT251822 Binding of POLG and C10orf2 1 0.42 0.29 0 5.00
22 INT300631 Binding of TSC1 and TSC2 1 0.15 2.59 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Diplopia. They are ordered first by their pain relevance and then by number of times they were reported in Diplopia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT70987 Binding of RAC1 14 0.37 12.14 2.13 99.16
2 INT267577 Localization of ERC1 1 0.78 3.84 2.71 99.08
3 INT128563 Binding of Mllt1 8 0.41 6.7 5.63 98.82
4 INT344063 Binding of Esl1 1 0.04 3.16 0.8 98.56
5 INT227557 Binding of FAM155B 1 0.08 3.66 0.45 98.56
6 INT150060 Localization of ACSM3 1 0.68 1.16 0.52 98.40
7 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 97.78
8 INT156794 Gene_expression of CISH 41 0.58 23.09 5.03 97.46
9 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33 97.04
10 INT1261 Localization of Adh1 63 0.81 19.36 16.09 96.32
11 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19 96.12
12 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 95.84
13 INT84653 Gene_expression of DPF1 2 0.30 1.3 0.1 95.64
14 INT19768 Negative_regulation of LAMC2 11 0.57 10.54 5.32 95.56
15 INT6511 Positive_regulation of AFP 76 0.70 70.15 7.28 95.40
16 INT14644 Binding of Tag 1 0.01 0.52 0.1 95.04
17 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 94.16
18 INT14360 Positive_regulation of DDC 7 0.70 2.97 2.02 94.00
19 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 93.64
20 INT10147 Gene_expression of Serpinc1 28 0.76 17.73 5.77 93.64
21 INT14690 Localization of CSF2 124 0.80 85.17 27.26 93.36
22 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 93.32
23 INT311448 Gene_expression of TAOK1 1 0.21 2.47 0.31 93.04
24 INT311439 Positive_regulation of Gene_expression of TAOK1 1 0.15 1.48 0.18 93.04
25 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32 92.84
26 INT165306 Localization of CCBE1 1 0.09 1.34 0.35 92.80
27 INT25271 Positive_regulation of MTG1 21 0.67 13.59 5.96 92.40
28 INT25797 Positive_regulation of OR2AL1P 5 0.09 5.14 0.99 92.36
29 INT639 Regulation of LAMC2 8 0.44 4.68 2.92 92.08
30 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 92.02
31 INT12324 Positive_regulation of PRTN3 26 0.70 18.82 4.55 91.96
32 INT86771 Positive_regulation of TAOK1 2 0.38 4.55 0.29 91.84
33 INT227549 Gene_expression of Tshr 4 0.35 4.32 0.24 91.84
34 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 91.68
35 INT86947 Gene_expression of Arigg3 6 0.58 3.62 0.57 91.52
36 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 91.52
37 INT153698 Negative_regulation of Positive_regulation of UPF1 1 0.08 0.72 0.09 91.44
38 INT51262 Positive_regulation of TKT 7 0.69 4.31 0.82 91.36
39 INT10721 Gene_expression of BDNF-AS 119 0.76 72.8 16.29 91.12
40 INT148702 Positive_regulation of UPF1 29 0.31 12.9 1.91 91.00
41 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 90.32
42 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 90.32
43 INT96720 Positive_regulation of GNA11 2 0.60 0.95 0.41 90.32
44 INT284568 Negative_regulation of Ods 1 0.05 2.51 0.11 90.28
45 INT597 Positive_regulation of PON1 26 0.62 19.14 2.87 89.92
46 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 89.72
47 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 89.60
48 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 89.52
49 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 89.40
50 INT300037 Localization of EEF1A2 2 0.73 2.02 0 89.36
51 INT88667 Negative_regulation of Gene_expression of F2 11 0.41 5.53 1.62 89.32
52 INT146340 Localization of Mllt1 10 0.69 4.6 5.45 89.12
53 INT311475 Regulation of Localization of Mllt1 1 0.39 1.1 0.94 89.12
54 INT128562 Regulation of Mllt1 2 0.39 1.1 0.74 89.12
55 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 88.68
56 INT103496 Gene_expression of Vps52 3 0.39 3.22 1.78 88.36
57 INT153699 Regulation of MTHFR 2 0.45 1.54 0.63 88.28
58 INT153697 Regulation of GRHPR 1 0.03 0.71 0.09 88.28
59 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 88.24
60 INT19396 Regulation of Rac1 66 0.53 37.41 30.01 87.40
61 INT16869 Positive_regulation of Prl 24 0.70 15.7 7.63 87.16
62 INT124063 Gene_expression of MTHFR 9 0.65 6.22 2.67 87.04
63 INT30209 Localization of SCN5A 24 0.72 7.95 5.35 86.96
64 INT53753 Positive_regulation of lgl 1 0.00 0.49 0.16 85.84
65 INT53754 Localization of lgl 1 0.01 0.49 0.16 85.84
66 INT8477 Negative_regulation of AFP 35 0.58 31.52 3.1 85.36
67 INT42038 Localization of ACE 26 0.80 8.88 7.06 85.20
68 INT4771 Gene_expression of CGB 23 0.67 14.22 3.42 85.16
69 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 84.88
70 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 84.60
71 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89 84.52
72 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 84.44
73 INT92386 Gene_expression of Tnfrsf8 14 0.54 13.55 1.67 84.44
74 INT33517 Gene_expression of TSHR 20 0.71 14.65 1.45 83.96
75 INT1921 Gene_expression of CEACAM7 47 0.78 43.23 2.53 83.72
76 INT10353 Positive_regulation of PGR 34 0.70 21.84 3.28 82.48
77 INT99682 Phosphorylation of Rac1 1 0.54 0.72 0.28 82.28
78 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 82.20
79 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 81.92
80 INT77670 Positive_regulation of ACLY 24 0.49 21.68 3.12 81.92
81 INT158 Localization of Prl 2431 0.81 378.96 952.2 81.60
82 INT311446 Negative_regulation of Gene_expression of PLXNA2 1 0.12 1.1 0.18 81.60
83 INT425 Localization of PRL 455 0.81 189.64 144.8 81.52
84 INT28872 Positive_regulation of CSRP1 49 0.70 47.23 11.7 81.28
85 INT168188 Gene_expression of PLXNA2 13 0.58 9 2.73 81.16
86 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 81.12
87 INT150144 Gene_expression of Kcnn3 31 0.78 7.67 4.24 80.96
88 INT150141 Positive_regulation of Gene_expression of Kcnn3 14 0.66 3.54 1.64 80.96
89 INT26078 Localization of ANTXRL 5 0.02 2.13 1 80.80
90 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 80.24
91 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 80.24
92 INT2005 Positive_regulation of Gene_expression of PRL 55 0.70 21.4 13.44 80.24
93 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 79.88
94 INT8669 Positive_regulation of Afp 66 0.70 58.21 7.67 79.76
95 INT90670 Positive_regulation of KRT1 10 0.44 6.25 1.16 79.76
96 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 79.72
97 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 78.80
98 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 78.72
99 INT120056 Gene_expression of NFIC 6 0.14 2.89 0.53 78.72
100 INT541 Positive_regulation of MBP 31 0.67 28.56 12.24 78.60
101 INT504 Gene_expression of GPT 42 0.75 27.54 3.99 78.52
102 INT745 Gene_expression of Afp 65 0.78 52.89 4.24 77.96
103 INT39357 Binding of Afp 5 0.48 3.58 0.85 77.96
104 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 77.76
105 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33 77.68
106 INT5843 Positive_regulation of Gfap 184 0.70 108.2 70.21 77.68
107 INT22707 Positive_regulation of Eno2 36 0.69 27.31 5.07 77.68
108 INT41928 Binding of AFP 9 0.36 7.85 0.7 77.64
109 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 77.20
110 INT344060 Gene_expression of Esl1 1 0.06 3.65 1.09 76.88
111 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 76.80
112 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 76.76
113 INT311438 Gene_expression of COL13A1 1 0.24 6.56 0.17 76.16
114 INT20055 Gene_expression of CRTAC1 19 0.58 15.49 4.73 76.12
115 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 75.00
116 INT150744 Negative_regulation of Gene_expression of SYP 4 0.41 2.35 0.2 75.00
117 INT24891 Gene_expression of SYP 55 0.75 45.76 7.53 75.00
118 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97 75.00
119 INT138715 Gene_expression of POLG 12 0.66 6.97 0.23 74.88
120 INT15837 Binding of CGA 31 0.41 12.06 3.17 74.28
121 INT122937 Binding of MLF1IP 1 0.19 1.83 0.11 74.12
122 INT75932 Binding of Csf2 45 0.37 33.2 8.01 73.88
123 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7 73.88
124 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 72.20
125 INT164328 Negative_regulation of SMARCB1 8 0.24 4.04 0.4 70.28
126 INT92388 Gene_expression of ALK 16 0.78 22.46 2.26 70.16
127 INT157772 Gene_expression of ASF1B 3 0.07 2.78 0.49 70.04
128 INT28774 Localization of LAMC2 6 0.73 3.2 0.76 69.16
129 INT9556 Negative_regulation of NAV1 47 0.59 28.49 49.33 67.80
130 INT9555 Negative_regulation of KCNQ2 3 0.57 0.92 0.56 67.80
131 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 67.20
132 INT307615 Negative_regulation of Positive_regulation of CSF2 4 0.36 3.55 0.48 67.20
133 INT1309 Positive_regulation of Localization of Gnrhr 152 0.69 24.25 81.56 66.96
134 INT222892 Binding of CACNA2D2 2 0.23 2.78 2.42 66.96
135 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 66.68
136 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 65.00
137 INT162 Regulation of Prl 794 0.62 165.01 322.24 64.88
138 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27 64.24
139 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 62.84
140 INT48390 Negative_regulation of Localization of CSF2 10 0.51 7.39 3.28 62.60
141 INT3400 Positive_regulation of pr 57 0.68 36.9 16.24 61.96
142 INT16214 Localization of F13A1 36 0.74 21.8 4.87 61.92
143 INT153313 Regulation of Localization of F13A1 2 0.36 2.34 0.48 61.92
144 INT242414 Regulation of Aes 5 0.23 1.82 1.16 61.84
145 INT344059 Positive_regulation of Esl1 1 0.04 1.54 0.48 61.00
146 INT17417 Positive_regulation of Ighd 16 0.69 24.29 2.8 59.52
147 INT59454 Regulation of Gene_expression of CSF2 22 0.52 19.67 2.69 59.44
148 INT227558 Gene_expression of FAM155B 1 0.12 1.82 0.06 59.20
149 INT114715 Binding of SRC 8 0.36 4.26 1.32 59.04
150 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31 58.88
151 INT28249 Positive_regulation of HLA-DRA 25 0.70 13.63 3.25 58.72
152 INT5118 Regulation of SST 97 0.62 34.35 51.74 58.00
153 INT10146 Negative_regulation of Vwf 27 0.40 17.11 3.69 57.16
154 INT93350 Binding of Lepr 17 0.05 27.21 1.5 53.48
155 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13 53.44
156 INT6625 Negative_regulation of Pth 96 0.58 57.6 8.24 53.20
157 INT18114 Gene_expression of NPC1 45 0.66 57.85 1.44 53.04
158 INT37103 Gene_expression of CHRNE 5 0.67 4.32 0.12 53.04
159 INT220700 Gene_expression of MUSK 3 0.75 6.67 0.07 53.04
160 INT97452 Positive_regulation of MOCS1 20 0.39 11.4 2.59 51.60
161 INT280447 Negative_regulation of Positive_regulation of MOCS1 1 0.00 0.75 0.69 51.60
162 INT344064 Localization of Esl1 1 0.06 1.25 0.35 51.36
163 INT1650 Regulation of TSHR 3 0.28 0.88 1.99 51.04
164 INT274104 Regulation of PLXNA2 2 0.33 2.66 0.25 51.04
165 INT76092 Localization of ISYNA1 10 0.66 7.72 3.11 50.92
166 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 50.20
167 INT311479 Gene_expression of Mllt1 4 0.58 4.92 2.39 50.08
168 INT22454 Regulation of Crp 213 0.62 160.67 49.24 49.84
169 INT243843 Negative_regulation of FMT 3 0.07 1.4 0.32 48.64
170 INT121967 Regulation of RAC1 9 0.45 6.14 3.41 48.20
171 INT75688 Binding of KITLG 24 0.30 11.73 4.06 47.44
172 INT19395 Negative_regulation of Localization of Pth 11 0.58 10.16 0.55 46.64
173 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 46.56
174 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 46.08
175 INT4097 Localization of Pth 66 0.81 47.17 4.36 45.60
176 INT52021 Regulation of IGHG3 34 0.39 22.43 3.3 44.24
177 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 43.76
178 INT208224 Protein_catabolism of TAOK1 1 0.05 0.94 0.04 43.52
179 INT344061 Regulation of Esl1 1 0.04 0.9 0.82 43.16
180 INT293961 Binding of PITX1 1 0.31 1.73 0.1 42.56
181 INT14149 Binding of C6orf25 11 0.48 9.04 1.71 41.24
182 INT69282 Binding of PHEX 4 0.15 1.43 0.41 41.24
183 INT167203 Binding of PRNP 25 0.48 20.09 1.84 39.68
184 INT2774 Binding of Crp 241 0.48 195.89 44.39 39.08
185 INT37296 Binding of Esr1 117 0.43 62.51 27.33 39.08
186 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 37.96
187 INT311478 Positive_regulation of Mllt1 4 0.60 2.38 2.34 36.08
188 INT274203 Positive_regulation of PABPN1 1 0.16 2.41 0.37 34.84
189 INT106952 Positive_regulation of NPC1 23 0.43 22.9 0.94 34.04
190 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 33.52
191 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 33.00
192 INT260525 Gene_expression of AMD1 25 0.66 24.58 1.32 33.00
193 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48 32.80
194 INT10536 Gene_expression of Trib3 67 0.66 27.08 21.58 32.80
195 INT10535 Positive_regulation of Gene_expression of Trib3 13 0.59 4.93 3.74 32.80
196 INT25906 Negative_regulation of Cish 6 0.29 5.41 3.17 32.12
197 INT24816 Binding of CD40LG 68 0.47 45.48 11.56 32.08
198 INT10019 Binding of CD8A 57 0.36 31.49 10.08 32.08
199 INT175904 Localization of RAC1 7 0.41 5.05 0.86 31.88
200 INT49209 Positive_regulation of GAD1 17 0.70 15.39 5.59 31.84
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