D:Disease Progression

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Disease Term
Synonyms Disease Progressions, PROGRESSION DISEASE, Progressions Disease
Documents 2605
Hot Single Events 200
Hot Interactions 98

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Disease Progression. They are ordered first by their relevance to Disease Progression and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT333051 Binding of HIVEP1 and NOLC1 1 0.00 4.11 0.07 99.96
2 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85 99.82
3 INT349355 CSF2 Negative_regulation of CSTA 1 0.01 1.43 0 99.24
4 INT188747 AGRP Positive_regulation of Gene_expression of CSF2 1 0.06 1.28 0 98.08
5 INT252344 Binding of Cd40 and Mthfd1 2 0.16 0.34 0.08 97.96
6 INT288538 Il2 Positive_regulation of Gene_expression of Bcl2 1 0.04 1.96 0.03 97.64
7 INT261893 Binding of Htt and Hap1 1 0.13 0.49 0 97.48
8 INT282128 Gene_expression of Il10 Positive_regulation of Positive_regulation of Icam1 1 0.37 1.12 0.28 97.12
9 INT249117 Binding of Abl1 and Bcr 4 0.36 2.22 0.09 96.56
10 INT311988 Il4 Positive_regulation of Mthfd1 1 0.08 0.28 0.08 96.52
11 INT311986 Csf2 Positive_regulation of Mthfd1 1 0.03 0.28 0.08 96.52
12 INT333772 Positive_regulation of Casp3 Positive_regulation of Gga3 1 0.05 0.5 0 96.12
13 INT333771 Casp3 Positive_regulation of Gga3 1 0.05 0.5 0 96.12
14 INT162436 Binding of Igfals and Tardbp 1 0.16 2.68 0 96.04
15 INT250253 Binding of AQP4 and SLC1A2 1 0.30 2.95 1.09 96.04
16 INT162435 Binding of Igfals and Rapsn 1 0.19 1.34 0 96.04
17 INT277555 Clrn1 Regulation of Localization of Pdc 1 0.05 0.7 0 95.84
18 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6 94.88
19 INT194362 PDGFA Regulation of EGFR 1 0.23 1.56 0 94.72
20 INT194361 VEGFA Regulation of EGFR 1 0.22 1.58 0 94.72
21 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 94.60
22 INT332242 Binding of Egf and Pdgfa 1 0.07 0.97 0.25 94.52
23 INT251492 Binding of HSPD1 and SOD1 1 0.02 1.45 0.18 94.00
24 INT344402 Binding of Crp and Spp1 1 0.05 2.92 0.28 93.92
25 INT102621 IL6 Regulation of Gene_expression of CPOX 1 0.13 0.78 0.25 93.48
26 INT102618 PTAFR Regulation of Gene_expression of CPOX 1 0.08 0.38 0 93.48
27 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 93.36
28 INT353191 Renbp Regulation of Gene_expression of Yif1 1 0.00 0.55 0 93.20
29 INT312218 INPP5K Positive_regulation of Protein_catabolism of IGFBP3 1 0.17 0.39 0.11 93.00
30 INT182819 Binding of CD63 and PECAM1 1 0.00 1.63 0.61 92.84
31 INT182815 Binding of CD63 and ICAM1 1 0.00 1.63 0.61 92.84
32 INT232417 Binding of Mtx1 and Ifx 1 0.04 0.99 0.86 92.80
33 INT170127 Binding of ITGAL and PECAM1 2 0.01 2.71 0.75 92.40
34 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14 92.00
35 INT250871 Il1a Positive_regulation of Protein_catabolism of Ecm1 1 0.01 1.44 0.68 92.00
36 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77 92.00
37 INT355817 BACE1 Regulation of NAV1 1 0.37 0.7 0.45 91.92
38 INT250878 Il1a Positive_regulation of Fgf8 Positive_regulation of Ecm1 1 0.01 0.85 0.38 91.24
39 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38 91.24
40 INT352082 Binding of CCR7 and ADAM11 1 0.15 0.76 0 91.16
41 INT352079 Binding of CD86 and ADAM11 1 0.10 0.77 0 91.16
42 INT352086 Binding of CD40 and ADAM11 1 0.08 0.77 0 91.16
43 INT172140 CSF2 Positive_regulation of Gene_expression of TIMP1 1 0.07 0.72 0.27 91.04
44 INT316883 Positive_regulation of Binding of Cd19 and Cd22 1 0.02 0.86 0.31 88.88
45 INT316884 Positive_regulation of Binding of Cr2 and Bcr 1 0.06 0.86 0.31 88.88
46 INT316886 Positive_regulation of Binding of Cd22 and Cr2 1 0.02 0.86 0.31 88.88
47 INT316881 Positive_regulation of Binding of Cd19 and Bcr 1 0.08 0.86 0.31 88.88
48 INT339585 Binding of AMD1 and MDM1 1 0.06 2.02 0 88.88
49 INT211127 Regulation of Binding of MTX1 and TNF 1 0.22 0.71 0.74 88.68
50 INT211130 Binding of MTX1 and TNF 1 0.18 0.7 0.73 88.68
51 INT262617 Ager Positive_regulation of Rpe 1 0.00 0.81 0 88.64
52 INT262620 Renbp Positive_regulation of Ager Positive_regulation of Rpe 1 0.00 0.81 0 88.64
53 INT184116 Il10 Positive_regulation of Stat3 2 0.18 1.15 0.77 88.08
54 INT254218 Binding of Il10 and Il10rb 1 0.00 0.87 0.32 88.08
55 INT254226 Binding of Il10 and Il10ra 1 0.00 0.87 0.32 88.08
56 INT311225 GLP1R Positive_regulation of Gene_expression of INS 1 0.49 0.33 0.06 87.68
57 INT316882 Binding of Cd22 and Cr2 1 0.02 1.71 0.61 87.36
58 INT316887 Binding of Cd19 and Cd22 1 0.02 0.85 0.31 87.36
59 INT316885 Binding of Cr2 and Bcr 1 0.06 0.85 0.3 86.68
60 INT316888 Binding of Cd19 and Bcr 1 0.08 0.85 0.3 86.68
61 INT162437 Binding of Igf1 and Igfals 1 0.10 1.45 0 86.40
62 INT316889 Binding of Cd19 and Cr2 1 0.07 1.7 0.61 86.32
63 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35 86.00
64 INT254213 Binding of Jak1 and Tyk2 1 0.09 0.84 0.33 85.84
65 INT309846 Binding of pad and Pah 1 0.03 0.98 0 85.68
66 INT254209 Jak1 Positive_regulation of Stat3 1 0.18 0.84 0.33 85.28
67 INT254217 Tyk2 Positive_regulation of Stat3 1 0.23 0.83 0.33 84.92
68 INT231305 Positive_regulation of Binding of Prnp and Helt 1 0.03 1.63 0.19 84.76
69 INT223578 INS Positive_regulation of PIK3CG 1 0.05 0.87 0 84.56
70 INT223576 PIK3CG Regulation of MTOR 1 0.15 0.37 0 84.56
71 INT223580 Positive_regulation of PIK3CG Regulation of MTOR 1 0.25 0.42 0 84.56
72 INT89381 INS Positive_regulation of AKT1 6 0.43 3.06 0.33 84.36
73 INT223575 AKT1 Regulation of MTOR 1 0.12 0.37 0 84.36
74 INT231303 Binding of Prnp and Helt 1 0.02 3.23 0.41 84.12
75 INT304756 Regulation of Binding of HIVEP1 and ERVV-2 1 0.00 1.46 0.03 83.92
76 INT261579 Serpinc1 Negative_regulation of Gene_expression of CYBB 1 0.00 1.69 0.18 83.76
77 INT193955 Binding of Psen1 and Psen2 1 0.37 1.64 0 83.76
78 INT284048 Binding of Cia1 and Vtcn1 1 0.02 1.37 0.6 83.68
79 INT294095 Binding of TXK and Gtf3a 1 0.00 2.33 0 83.60
80 INT304757 Binding of HIVEP1 and ERVV-2 1 0.00 1.41 0.03 83.48
81 INT301241 Mir29a Positive_regulation of Runx1 1 0.00 2.85 0 82.88
82 INT288537 Binding of Ccr3 and Ccl11 1 0.17 2.92 0.35 82.80
83 INT137074 IFNG Positive_regulation of Protein_catabolism of DOHH 1 0.04 1.06 0.21 82.64
84 INT137072 IFNG Positive_regulation of DOHH 1 0.05 1.05 0.21 82.64
85 INT207117 Binding of VEGFA and F2r 1 0.02 0.56 0.15 82.64
86 INT352073 Positive_regulation of Binding of ADAM11 and CCL19 1 0.22 1.27 0.13 82.52
87 INT352080 Binding of ADAM11 and CCL19 1 0.16 1.27 0.13 82.52
88 INT106074 IL1B Positive_regulation of Gene_expression of A2M 1 0.03 0.75 0.49 82.48
89 INT106072 NFKB1 Positive_regulation of Gene_expression of A2M 1 0.19 0.75 0.49 82.48
90 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34 81.88
91 INT204552 Sult2a2 Regulation of Cia1 1 0.01 2.75 1.75 81.32
92 INT335851 Snrpc Positive_regulation of Il10 1 0.01 1.17 0.5 81.24
93 INT237415 Il1rn Regulation of Il10 1 0.03 0.96 0.39 80.96
94 INT237417 Il1rn Regulation of Il4 1 0.02 0.96 0.39 80.96
95 INT277860 MUC4 Negative_regulation of ERBB2 1 0.19 0.29 0 80.28
96 INT224724 Gm2458 Negative_regulation of Metap2 1 0.02 1.57 0.57 80.24
97 INT245217 Binding of CREM and TFAM 1 0.00 1.44 0 80.20
98 INT353129 Binding of CD4 and CXCR4 1 0.13 1.08 0 80.16
99 INT312212 Binding of ADAM12 and INPP5K 1 0.16 0.46 0.11 79.96
100 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54 79.80
101 INT262618 Binding of SOAT1 and Kras 1 0.00 0.81 0.12 79.68
102 INT240729 Binding of CRP and HLA-A 1 0.11 2.18 0.71 79.36
103 INT284213 Binding of Cd4 and Mela 1 0.06 0.6 0.14 79.20
104 INT284224 Binding of Cd4 and Hivan1 1 0.01 0.6 0.14 79.20
105 INT327164 RETNLB Regulation of TNF 1 0.00 2.27 0.6 79.12
106 INT106073 IL1B Positive_regulation of Positive_regulation of NFKB1 1 0.41 0.7 0.47 79.00
107 INT210595 Binding of TNF and TNFSF11 1 0.10 5.13 0.09 78.64
108 INT220902 Binding of C4b and C4bp 1 0.45 1.02 0 78.48
109 INT220907 Binding of C4bp and Cfb 1 0.08 0.52 0 78.48
110 INT309906 Binding of EGF and SRC 1 0.11 0.64 0 78.32
111 INT297736 Cbr1 Positive_regulation of Ucp3 1 0.11 1.29 0.07 78.28
112 INT297735 Cbr1 Positive_regulation of Sod2 1 0.11 1.28 0.07 78.28
113 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84 78.24
114 INT287699 TNF Regulation of Binding of VEGFA 1 0.02 0.46 0.27 77.48
115 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 77.24
116 INT311227 INS Negative_regulation of HBA1 1 0.01 0.52 0.16 77.12
117 INT327167 RETNLB Regulation of IL6 1 0.00 2.26 0.6 76.96
118 INT240131 Binding of Crp and Nppb 7 0.07 11.53 2.12 76.40
119 INT297737 Cbr1 Positive_regulation of Bax 1 0.06 0.53 0.03 76.24
120 INT305504 Slc17a6 Positive_regulation of Ex 1 0.05 0.67 0.22 76.16
121 INT326571 Binding of Hsf1 and Hsp90ab1 1 0.16 1.19 0.03 76.08
122 INT326570 Hsp90ab1 Regulation of Csprs 1 0.08 1.17 0.03 76.08
123 INT254206 Il10 Negative_regulation of Chuk 1 0.05 0.59 0.29 75.92
124 INT254208 Il10 Negative_regulation of Regulation of Chuk 1 0.05 0.59 0.29 75.92
125 INT327166 RETNLB Regulation of IL36RN 1 0.00 2.25 0.59 75.76
126 INT267217 Gene_expression of Hspb8 Negative_regulation of Positive_regulation of Casp3 1 0.14 2.8 0.04 75.76
127 INT237419 Binding of Hif1a and Bace1 Positive_regulation of Bace1 1 0.06 1.2 0.15 75.68
128 INT237420 Binding of Hif1a and Bace1 Positive_regulation of Positive_regulation of Bace1 1 0.06 1.2 0.15 75.68
129 INT293973 Binding of POMC and Mc1r 1 0.37 1.8 0.07 75.52
130 INT144588 Binding of EEF1A2 and pad 1 0.36 1.34 0.24 75.00
131 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 74.80
132 INT304340 FKBP5 Regulation of NR3C1 1 0.05 0.71 0.37 74.80
133 INT214919 Pkd1 Positive_regulation of CDKN1A 1 0.51 2.6 0 74.64
134 INT250864 Fgf8 Positive_regulation of Positive_regulation of Ptger2 1 0.03 0.55 0.28 74.64
135 INT239438 Binding of OPA1 and LIPG 1 0.03 1.21 0.04 74.24
136 INT250854 Fgf8 Positive_regulation of Positive_regulation of Mmp3 1 0.11 0.55 0.28 73.92
137 INT324692 Binding of Cd14 and Sod1m 1 0.01 1.07 0.03 73.68
138 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 73.44
139 INT327165 RETNLB Regulation of Gene_expression of CRP 1 0.01 2.25 0.59 73.44
140 INT291354 CXCL12 Positive_regulation of EPHB2 1 0.42 2.02 0.16 73.12
141 INT291356 CXCL12 Positive_regulation of AKT1 1 0.04 1.28 0.03 73.12
142 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83 73.08
143 INT278696 MTX1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83 72.88
144 INT291349 CXCR4 Positive_regulation of EPHB2 1 0.42 1.87 0.13 72.80
145 INT291357 CXCR4 Positive_regulation of AKT1 1 0.08 1.27 0.03 72.80
146 INT237418 Binding of Hif1a and Bace1 1 0.06 1.18 0.15 71.52
147 INT193970 Binding of PSEN1 and Psen2 1 0.36 2.06 0.05 71.36
148 INT193967 Binding of PSEN1 and Psen1 1 0.41 1.2 0.05 70.72
149 INT352084 AGRP Negative_regulation of Negative_regulation of ADAM11 1 0.06 0.98 0.11 70.16
150 INT292156 Binding of HIVEP1 and SFTPA1 1 0.00 0.49 0 69.84
151 INT235431 cla Positive_regulation of Ppara 1 0.06 0.6 0 69.52
152 INT235432 Ppara Negative_regulation of Gene_expression of Cpox 1 0.01 1 0.37 69.44
153 INT346598 Negative_regulation of Binding of Mapk3 and Sh2d1b2 1 0.22 0.2 0 69.44
154 INT333774 sal Positive_regulation of Bace1 1 0.18 0.07 0 69.12
155 INT346595 Binding of Mapk3 and Sh2d1b2 1 0.19 0.2 0 68.92
156 INT352076 Binding of TLR4 and Positive_regulation of ADAM11 1 0.06 1.09 0.04 68.28
157 INT352087 Binding of ADAM11 and TLR4 1 0.05 1.09 0.04 67.88
158 INT296945 ADIPOQ Negative_regulation of TNF 1 0.03 1.13 0.4 67.60
159 INT146806 Tnfrsf11b Positive_regulation of Pth 1 0.46 1.43 0 67.44
160 INT322206 CCL18 Positive_regulation of Gene_expression of COL7A1 1 0.05 0.28 0.05 67.12
161 INT211669 Tnni2 Negative_regulation of Dnahc8 1 0.01 0.57 0 66.72
162 INT284219 Binding of Ccr5 and Avpr1b 1 0.01 0.46 0.12 66.28
163 INT284218 Binding of Cxcr4 and Avpr1b 1 0.00 0.46 0.12 66.28
164 INT284211 Binding of Avpr1b and Eclc 1 0.00 0.46 0.12 66.28
165 INT284223 Positive_regulation of Binding of Avpr1b and Eclc 1 0.00 0.46 0.12 66.28
166 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 66.24
167 INT252366 Binding of RUNX1 and CD80 1 0.01 0.54 0.2 66.24
168 INT211673 Tnni2 Negative_regulation of Dnahc8 1 0.06 0.52 0 65.96
169 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07 65.60
170 INT209633 AR Regulation of Gene_expression of PCa 1 0.06 1.19 0 65.28
171 INT223574 PTEN Negative_regulation of AKT1 1 0.06 0.56 0 65.16
172 INT223579 PTEN Negative_regulation of PIK3CG 1 0.18 0.56 0 65.16
173 INT245072 PPARA Regulation of Gene_expression of CXCR4 1 0.07 0.68 0.26 65.12
174 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22 64.84
175 INT222777 IL4 Positive_regulation of Positive_regulation of MR1 1 0.03 0.45 0.12 64.84
176 INT222774 IL4 Positive_regulation of MRC1 1 0.01 0.45 0.12 64.84
177 INT222786 IL4 Positive_regulation of Positive_regulation of MRC1 1 0.01 0.45 0.12 64.84
178 INT222748 IL4 Positive_regulation of IL4 Positive_regulation of MR1 1 0.01 0.45 0.12 64.84
179 INT222780 IL4 Positive_regulation of MR1 1 0.02 0.45 0.12 64.84
180 INT252367 Binding of RUNX1 and CTLA4 1 0.02 0.48 0.18 64.64
181 INT272951 Binding of TNF and Igf1 1 0.14 1.48 0.36 64.60
182 INT272953 Negative_regulation of Binding of TNF and Igf1 1 0.16 1.48 0.36 64.60
183 INT102627 IL6 Positive_regulation of Gene_expression of CPOX 1 0.20 0.34 0 64.48
184 INT247114 Binding of HLA-A and MPZ 1 0.00 6.26 0 64.48
185 INT209645 AR Regulation of STUB1 1 0.04 0.93 0.13 64.28
186 INT322207 CCL18 Regulation of Gene_expression of COL7A1 1 0.07 0.88 0.09 63.76
187 INT254199 Il10 Positive_regulation of Gene_expression of Socs3 2 0.06 0.75 0.63 63.44
188 INT100783 Binding of CYP2B6 and CYP3A4 2 0.17 2 0.77 63.20
189 INT274170 Il13 Regulation of Il4 3 0.09 2.75 0.51 63.12
190 INT256321 INCENP Positive_regulation of Gene_expression of Vcam1 1 0.00 1.89 0.38 62.96
191 INT274167 Il13 Regulation of Il5 2 0.09 2.05 0.59 62.88
192 INT272952 Igf1 Positive_regulation of Localization of TNF 1 0.19 1.53 0.35 62.36
193 INT214917 Pkd1 Positive_regulation of Negative_regulation of CDKN1A 1 0.37 1.46 0 62.16
194 INT128652 ITIH4 Regulation of Gene_expression of CCR5 1 0.36 1.46 0.93 61.36
195 INT250873 Fgf8 Positive_regulation of GAG 1 0.55 0.48 0.23 61.12
196 INT128655 ITIH4 Regulation of Gene_expression of CCR3 1 0.36 1.45 0.92 60.64
197 INT218668 Binding of Ppia and Olr811 1 0.00 0.98 0.05 60.48
198 INT202038 MMP9 Positive_regulation of IL8 1 0.05 0.29 0.59 60.36
199 INT263100 Binding of EFS and COPD 1 0.14 4.14 0.07 59.60
200 INT352075 AGRP Negative_regulation of Positive_regulation of ADAM11 1 0.06 1.64 0.04 59.36

Single Events

The table below shows the top 200 pain related interactions that have been reported for Disease Progression. They are ordered first by their pain relevance and then by number of times they were reported in Disease Progression. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT283503 Binding of SLC4A2 3 0.09 3.39 0.19 100.00
2 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 100.00
3 INT272275 Regulation of Positive_regulation of NARFL 8 0.36 16.68 0.86 100.00
4 INT334212 Negative_regulation of DLEU1 2 0.28 8.84 0.53 100.00
5 INT86751 Negative_regulation of Il10 62 0.59 40.1 20.51 100.00
6 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 99.96
7 INT2139 Negative_regulation of Cea 55 0.43 43.59 9.14 99.96
8 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 99.96
9 INT77281 Negative_regulation of HIVEP1 132 0.49 102.78 5.36 99.96
10 INT299967 Negative_regulation of FTSJ3 1 0.07 11.72 0.97 99.96
11 INT142584 Regulation of Negative_regulation of Cplx2 1 0.27 1.4 0.22 99.96
12 INT351372 Regulation of Localization of Ntrk1 1 0.34 0.92 0 99.96
13 INT301210 Gene_expression of Mvd 1 0.19 1.48 0 99.96
14 INT227413 Gene_expression of DLAT 12 0.44 13.21 1.36 99.92
15 INT91758 Binding of CCR5 28 0.45 20.16 7.07 99.92
16 INT166881 Positive_regulation of Ccr1 31 0.69 18.14 7.9 99.92
17 INT46721 Regulation of Csf2 26 0.45 20.4 6.18 99.92
18 INT49564 Positive_regulation of PTGDR 8 0.70 3.28 4.62 99.92
19 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 99.82
20 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 99.82
21 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 99.80
22 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 99.80
23 INT136503 Negative_regulation of KDR 46 0.48 43.1 1.86 99.80
24 INT204929 Binding of IL33 18 0.08 4.74 0.7 99.80
25 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 99.76
26 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 99.76
27 INT59454 Regulation of Gene_expression of CSF2 22 0.52 19.67 2.69 99.76
28 INT2774 Binding of Crp 241 0.48 195.89 44.39 99.76
29 INT267280 Transcription of BCL11B 1 0.69 1.37 0 99.76
30 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 99.76
31 INT58756 Binding of GPI 10 0.48 7.17 3 99.76
32 INT41892 Gene_expression of HBM 48 0.64 28.32 5.64 99.74
33 INT241797 Gene_expression of CHIT1 10 0.24 9.75 0.69 99.74
34 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66 99.72
35 INT234263 Negative_regulation of ELF3 6 0.39 3.9 0.04 99.70
36 INT307721 Gene_expression of PALLD 1 0.76 45.01 0.89 99.68
37 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 99.68
38 INT307720 Positive_regulation of Gene_expression of PALLD 1 0.68 14.69 0.21 99.68
39 INT126566 Binding of Ifnb1 3 0.31 2.43 0.85 99.68
40 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 99.68
41 INT112334 Regulation of NF1 18 0.52 15.85 0.34 99.68
42 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54 99.60
43 INT137795 Positive_regulation of BACE1 3 0.68 4.74 4.31 99.60
44 INT28510 Positive_regulation of Gpi 21 0.68 6.75 14.27 99.60
45 INT104673 Positive_regulation of Obfc1 10 0.41 4.26 5.61 99.60
46 INT99778 Localization of Cxcl10 12 0.75 14.24 3.91 99.58
47 INT344160 Localization of Cxcl9 1 0.63 5.88 1.41 99.58
48 INT285490 Localization of Cxcl11 2 0.43 5.29 1.03 99.58
49 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 99.56
50 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 99.56
51 INT143230 Gene_expression of CRYGD 61 0.65 52.11 15.93 99.56
52 INT3823 Positive_regulation of ALPI 27 0.69 19.49 2.15 99.56
53 INT352108 Positive_regulation of ADAM11 1 0.49 35.19 1.59 99.54
54 INT243382 Positive_regulation of CSTA 4 0.05 14.65 0.12 99.52
55 INT195060 Gene_expression of ALPL 9 0.73 4.82 1.3 99.52
56 INT195058 Positive_regulation of Gene_expression of ALPL 3 0.65 1.56 0.42 99.52
57 INT127459 Negative_regulation of PAH 18 0.56 15.15 1.05 99.52
58 INT68702 Negative_regulation of C4bp 6 0.57 7.44 0.5 99.52
59 INT6511 Positive_regulation of AFP 76 0.70 70.15 7.28 99.50
60 INT63036 Negative_regulation of CSTA 4 0.36 9.42 0.22 99.48
61 INT36287 Binding of CD4 96 0.47 58.93 11.88 99.48
62 INT17182 Binding of Cea 25 0.48 14.98 4.16 99.48
63 INT22455 Binding of Nbr1 8 0.21 10.57 0.93 99.48
64 INT129106 Negative_regulation of Mstn 102 0.57 30.57 0.49 99.46
65 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57 99.44
66 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 99.44
67 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74 99.44
68 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 99.44
69 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 99.44
70 INT115889 Binding of Fas 27 0.36 28.87 4.08 99.44
71 INT352110 Gene_expression of ADAM11 1 0.55 24.56 1.15 99.42
72 INT20200 Positive_regulation of Serpinc1 25 0.68 17.08 4.98 99.42
73 INT171924 Gene_expression of MAPK14 60 0.65 54.38 21.68 99.40
74 INT70970 Binding of COPD 144 0.42 180.34 18.29 99.40
75 INT206244 Binding of CD24 7 0.48 5.71 1.43 99.40
76 INT5967 Negative_regulation of Il1a 51 0.57 27.09 18.24 99.40
77 INT5308 Regulation of Il1a 17 0.44 10.8 7.31 99.40
78 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 99.36
79 INT156669 Regulation of Pbr 1 0.22 0.92 0.37 99.36
80 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72 99.36
81 INT26502 Negative_regulation of Gene_expression of MMP2 39 0.58 21.45 9.42 99.36
82 INT284038 Positive_regulation of Protein_catabolism of Cia1 1 0.13 1.1 0.29 99.36
83 INT284006 Protein_catabolism of Cia1 1 0.23 1.1 0.29 99.36
84 INT174294 Regulation of Transcription of HGF 1 0.02 1.55 0.14 99.36
85 INT204737 Negative_regulation of Gene_expression of Prnp 32 0.59 18.96 1.03 99.32
86 INT142585 Negative_regulation of Cplx2 1 0.59 9.69 1.72 99.32
87 INT77415 Localization of GLP1R 23 0.63 11.1 1.69 99.32
88 INT178191 Regulation of Erbb2 7 0.36 4.11 0.24 99.32
89 INT44602 Gene_expression of TNFSF13B 37 0.75 30.98 9.96 99.28
90 INT150223 Regulation of Gene_expression of TNFSF13B 2 0.21 3.44 1.8 99.28
91 INT259666 Negative_regulation of Gene_expression of Hdac2 1 0.13 0.84 0.08 99.28
92 INT259669 Negative_regulation of Transcription of Hdac2 1 0.13 0.84 0.08 99.28
93 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 99.24
94 INT10796 Gene_expression of CYP2B6 131 0.77 30.14 35.27 99.24
95 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 99.24
96 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 99.24
97 INT215941 Gene_expression of MMP25 2 0.58 7 1.4 99.24
98 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 99.24
99 INT163245 Gene_expression of SRR 3 0.55 1.96 0.41 99.24
100 INT321259 Binding of MPEG1 1 0.20 2.25 0.21 99.22
101 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5 99.20
102 INT181790 Gene_expression of FLT4 13 0.72 11.73 0.56 99.20
103 INT11941 Binding of Slc11a1 3 0.14 2.18 0.35 99.20
104 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36 99.20
105 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39 99.20
106 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 99.20
107 INT284029 Protein_catabolism of Vtcn1 1 0.12 1.1 0.29 99.20
108 INT284023 Positive_regulation of Protein_catabolism of Vtcn1 1 0.07 1.1 0.29 99.20
109 INT69569 Positive_regulation of Prnp 175 0.70 96.31 13.34 99.18
110 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 99.16
111 INT336845 Positive_regulation of COL9A3 1 0.05 1.42 0 99.16
112 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 99.12
113 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 99.12
114 INT67037 Gene_expression of Sod1 121 0.78 59.32 7.99 99.12
115 INT186731 Positive_regulation of Ccl11 10 0.45 10.09 2.44 99.12
116 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 99.12
117 INT157943 Positive_regulation of IL-17 10 0.58 6.65 2.43 99.12
118 INT272437 Positive_regulation of Transcription of PROK2 1 0.30 1.67 0 99.12
119 INT291522 Positive_regulation of DHFRL1 1 0.24 0.62 0 99.10
120 INT132036 Negative_regulation of DPP4 126 0.59 63.24 9.51 99.08
121 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27 99.08
122 INT1939 Localization of Cys1 6 0.73 5.9 0.64 99.08
123 INT286532 Localization of Prkd1 3 0.58 3.02 0.16 99.08
124 INT286544 Localization of Ift88 1 0.52 1.26 0 99.08
125 INT286540 Localization of Btk 1 0.28 1.26 0 99.08
126 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 99.04
127 INT174422 Binding of Cxcr3 24 0.47 26.09 8.34 99.04
128 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 99.00
129 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96 98.96
130 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 98.92
131 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 98.92
132 INT118870 Positive_regulation of STAT1 36 0.67 26.18 5.46 98.92
133 INT118035 Positive_regulation of JAK1 23 0.67 10.57 3.29 98.92
134 INT350501 Positive_regulation of Prss27 1 0.02 2.91 0.12 98.92
135 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11 98.88
136 INT1218 Negative_regulation of Maob 24 0.59 9.76 9.39 98.88
137 INT94127 Positive_regulation of Il18 14 0.69 14 7.47 98.88
138 INT71220 Positive_regulation of Casp1 15 0.38 10.23 5.84 98.88
139 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 98.84
140 INT236089 Regulation of Negative_regulation of Hrec 1 0.03 1.56 0.55 98.84
141 INT236090 Regulation of Negative_regulation of S100a8 1 0.02 1.55 0.54 98.84
142 INT12035 Regulation of F2 21 0.45 12.66 1.47 98.84
143 INT197173 Positive_regulation of Cyp4a10 29 0.62 15.68 1.61 98.82
144 INT197166 Gene_expression of Cyp4a10 27 0.75 15.63 1.81 98.82
145 INT197174 Positive_regulation of Gene_expression of Cyp4a10 17 0.67 8.65 1.4 98.82
146 INT191807 Gene_expression of CD24 75 0.78 53.92 3.34 98.80
147 INT812 Localization of INS 1026 0.81 515.6 145.31 98.80
148 INT142586 Regulation of Cplx2 1 0.45 1.51 0.23 98.80
149 INT11657 Gene_expression of ALPI 11 0.71 5.13 0.74 98.76
150 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 98.76
151 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 98.76
152 INT186738 Positive_regulation of Gene_expression of Ccl11 14 0.67 8.55 1.45 98.76
153 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 98.76
154 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36 98.76
155 INT193836 Regulation of Ps 4 0.09 1.89 1.5 98.76
156 INT291508 Positive_regulation of Irx2 1 0.15 0.61 0 98.76
157 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 98.74
158 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 98.72
159 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82 98.72
160 INT64171 Regulation of CPOX 109 0.36 55.36 32.96 98.72
161 INT110208 Binding of ABR 2 0.35 10.49 0.81 98.72
162 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 98.68
163 INT168410 Gene_expression of Cxcr3 81 0.75 84.03 37.01 98.68
164 INT153670 Positive_regulation of Gene_expression of CAV1 26 0.69 44.27 0.92 98.64
165 INT165452 Gene_expression of Vtcn1 26 0.63 23.63 9.91 98.64
166 INT102694 Localization of CREM 4 0.27 1.6 1.8 98.64
167 INT65730 Gene_expression of Cnr2 129 0.78 60.15 63.1 98.62
168 INT127046 Gene_expression of P2RX7 65 0.78 34.28 14.76 98.62
169 INT211652 Gene_expression of Tnfrsf9 7 0.71 4.43 0.21 98.60
170 INT7105 Gene_expression of pad 54 0.77 63.68 8.8 98.56
171 INT95733 Transcription of pad 2 0.68 2.01 0.15 98.56
172 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91 98.52
173 INT157416 Positive_regulation of Samsn1 6 0.53 4.28 0.33 98.52
174 INT272435 Transcription of PROK2 1 0.34 1.66 0 98.52
175 INT291627 Binding of CSTA 2 0.04 1.58 0.08 98.50
176 INT277526 Gene_expression of Clrn1 1 0.78 29.02 0.17 98.48
177 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 98.48
178 INT187789 Positive_regulation of Positive_regulation of Bace1 18 0.50 16.18 1.87 98.48
179 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 98.48
180 INT284025 Binding of Cd274 1 0.07 1.1 0.28 98.48
181 INT259008 Positive_regulation of Gene_expression of TNFRSF18 1 0.49 0.89 0.13 98.48
182 INT291519 Positive_regulation of Sgce 1 0.16 0.61 0 98.46
183 INT132246 Negative_regulation of S100a8 19 0.43 22 7.25 98.44
184 INT90372 Negative_regulation of Hrec 12 0.03 11.73 4.74 98.44
185 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 98.44
186 INT301208 Gene_expression of Mir29a 1 0.17 26.18 0 98.44
187 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31 98.44
188 INT29138 Positive_regulation of Localization of IL2 25 0.50 10.06 3.89 98.44
189 INT10763 Localization of IL2 157 0.80 81.11 33.21 98.44
190 INT2006 Gene_expression of fc 104 0.34 64.91 19.08 98.44
191 INT106433 Regulation of CCR5 11 0.59 6.93 2.75 98.44
192 INT63037 Regulation of CSTA 10 0.37 13.37 0.92 98.40
193 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 98.40
194 INT86998 Regulation of HIVEP1 49 0.44 37.83 4 98.40
195 INT232362 Gene_expression of Mgmt 10 0.76 8.08 0.41 98.40
196 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 98.40
197 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08 98.40
198 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18 98.40
199 INT10353 Positive_regulation of PGR 34 0.70 21.84 3.28 98.40
200 INT232363 Positive_regulation of Gene_expression of Mgmt 8 0.49 6.01 0.28 98.40
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