D:Disorders Of Galactose Metabolism

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Disease Term
Synonyms CLASSIC GALACTOSEMIA, Classic Galactosemias, Deficiency Disease Galactokinase, DEFICIENCY DISEASE GALACTOSE 1 PHOSPHATE URIDYL TRANSFERASE, Deficiency Disease Udp Galactose 4 Epimerase, Deficiency Disease Udpglucose 4 Epimerase, DEFICIENCY DISEASES UDP GALACTOSE 4 EPIMERASE, DISEASE UDP GALACTOSE 4 EPIMERASE DEFICIENCY, Diseases Udp Galactose 4 Epimerase Deficiency, Disorder Of Galactose Metabolism, Galactokinase Deficiency Disease
Documents 11
Hot Single Events 10
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Disorders Of Galactose Metabolism. They are ordered first by their relevance to Disorders Of Galactose Metabolism and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT14440 Binding of GLB1 and NEU1 1 0.00 0.09 0.05 90.00
2 INT214481 ROS1 Negative_regulation of Gene_expression of INS 1 0.00 0.37 0.22 5.00
3 INT214480 SELPLG Negative_regulation of Positive_regulation of NFKB1 1 0.00 0.6 0.14 5.00
4 INT277089 VEGFA Positive_regulation of Icam1 1 0.02 1.74 0.09 5.00
5 INT277091 VEGFA Positive_regulation of Fas 1 0.03 1.72 0.09 5.00
6 INT277090 VEGFA Positive_regulation of Negative_regulation of Faslg 1 0.02 1.67 0.09 5.00
7 INT340379 Binding of Rabep1 and Ocrl 1 0.08 0.62 0 5.00
8 INT340380 Binding of Cfl1 and Clcn4-2 1 0.13 0.82 0 5.00
9 INT340378 Binding of Cfl1 and Clcn5 1 0.15 0.82 0 5.00
10 INT340377 Binding of Clcn4-2 and Clcn5 1 0.35 0.82 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Disorders Of Galactose Metabolism. They are ordered first by their pain relevance and then by number of times they were reported in Disorders Of Galactose Metabolism. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT27446 Negative_regulation of CTSA 11 0.57 5.58 3.08 98.44
2 INT14447 Localization of F2 20 0.79 12.77 2.67 97.12
3 INT14448 Localization of COL5A2 34 0.67 17.35 2.85 96.64
4 INT14444 Localization of WDYHV1 1 0.09 0.1 0 96.12
5 INT14450 Binding of NEU1 7 0.14 5.1 0.5 90.00
6 INT14443 Binding of GLB1 2 0.36 0.09 0.05 88.56
7 INT186142 Gene_expression of Ghrh 45 0.66 34.04 6.94 88.12
8 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 84.76
9 INT5420 Binding of CPN2 3 0.35 0.08 0.51 83.12
10 INT14446 Binding of TRAFD1 2 0.03 0.93 0.11 81.28
11 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 72.20
12 INT28308 Localization of SLC17A5 10 0.73 6.77 0.7 72.20
13 INT6481 Binding of TNF 624 0.48 510.2 214.82 29.52
14 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 28.32
15 INT14445 Negative_regulation of KLK11 3 0.32 1.71 0.32 26.16
16 INT129 Localization of OXTR 51 0.80 11.08 15.36 25.00
17 INT14442 Localization of GBE1 19 0.31 9.09 5.03 25.00
18 INT14449 Negative_regulation of WDYHV1 1 0.06 0 0.24 25.00
19 INT205587 Negative_regulation of Cyp17a1 1 0.28 0.24 0 16.00
20 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
21 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
22 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 5.00
23 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
24 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68 5.00
25 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
26 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
27 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 5.00
28 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
29 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
30 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 5.00
31 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63 5.00
32 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7 5.00
33 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 5.00
34 INT14587 Positive_regulation of Cl 44 0.20 20.37 16.72 5.00
35 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17 5.00
36 INT81629 Positive_regulation of Fas 58 0.70 59.63 12.94 5.00
37 INT86851 Gene_expression of Faslg 45 0.75 24.42 9.21 5.00
38 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36 5.00
39 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53 5.00
40 INT69439 Regulation of ROS1 46 0.45 31.22 6.94 5.00
41 INT23246 Gene_expression of HLA-DRB4 37 0.64 36.79 6.61 5.00
42 INT25022 Binding of PAEP 66 0.42 22.83 6.59 5.00
43 INT157932 Positive_regulation of ADHD1 46 0.48 52.18 6.13 5.00
44 INT17913 Regulation of HSD11B1 87 0.60 93.23 6.04 5.00
45 INT95048 Negative_regulation of ADHD1 61 0.51 56.01 5.62 5.00
46 INT88019 Positive_regulation of Gene_expression of Faslg 16 0.67 11.31 5.05 5.00
47 INT67138 Gene_expression of Gc 19 0.31 17.11 4.1 5.00
48 INT14880 Positive_regulation of Car3 14 0.65 9.19 3.73 5.00
49 INT9256 Gene_expression of SELPLG 30 0.75 16.44 3.66 5.00
50 INT204524 Binding of TLR9 17 0.43 11.69 2.76 5.00
51 INT102147 Negative_regulation of Faslg 5 0.19 4.56 1.92 5.00
52 INT3911 Gene_expression of TNFAIP1 29 0.65 21.68 1.85 5.00
53 INT88918 Gene_expression of Casp8 13 0.67 11.49 1.56 5.00
54 INT88015 Positive_regulation of Faslg 5 0.65 5.73 1.44 5.00
55 INT88917 Positive_regulation of Casp8 18 0.60 14.64 1.36 5.00
56 INT9257 Positive_regulation of SELPLG 5 0.45 3.57 1.16 5.00
57 INT105543 Gene_expression of DNTT 11 0.65 4.63 1 5.00
58 INT218315 Gene_expression of RBP4 25 0.76 18.19 0.85 5.00
59 INT182077 Positive_regulation of RFC1 3 0.07 1.65 0.81 5.00
60 INT151525 Gene_expression of Olfr148 7 0.67 8.5 0.74 5.00
61 INT294932 Negative_regulation of Gc 6 0.17 3.38 0.71 5.00
62 INT163993 Gene_expression of Hnf1a 2 0.65 1.38 0.49 5.00
63 INT173912 Negative_regulation of LRP2 5 0.57 6.22 0.42 5.00
64 INT277084 Negative_regulation of Gene_expression of Olfr148 1 0.06 1.91 0.38 5.00
65 INT117096 Gene_expression of Wnt4 2 0.67 4.68 0.38 5.00
66 INT88021 Regulation of Gene_expression of Faslg 4 0.60 2.6 0.38 5.00
67 INT204282 Negative_regulation of Casp8 3 0.51 3.35 0.37 5.00
68 INT56433 Negative_regulation of Cl 3 0.13 1.87 0.35 5.00
69 INT151527 Positive_regulation of Olfr148 4 0.40 3.76 0.35 5.00
70 INT277083 Localization of Olfr148 1 0.11 1.12 0.25 5.00
71 INT151526 Regulation of Olfr148 2 0.23 1.93 0.2 5.00
72 INT214504 Localization of SELPLG 2 0.23 0.88 0.2 5.00
73 INT164753 Negative_regulation of Clcn5 2 0.58 5.13 0.2 5.00
74 INT214503 Gene_expression of FADS3 3 0.75 7.81 0.18 5.00
75 INT233570 Gene_expression of Rbp4 4 0.66 3.4 0.17 5.00
76 INT340373 Negative_regulation of Rbp4 1 0.17 1.96 0.16 5.00
77 INT233012 Positive_regulation of Positive_regulation of Casp8 4 0.10 3.53 0.12 5.00
78 INT240179 Gene_expression of Tnfrsf25 4 0.45 2.87 0.12 5.00
79 INT277088 Negative_regulation of Gene_expression of DNTT 1 0.41 0.36 0.08 5.00
80 INT277082 Protein_catabolism of Fas 1 0.37 1.48 0.07 5.00
81 INT340358 Negative_regulation of Positive_regulation of Cl 1 0.13 0.79 0.04 5.00
82 INT340375 Negative_regulation of Cubn 1 0.24 0.77 0.03 5.00
83 INT340360 Positive_regulation of Clcn5 1 0.50 1.62 0 5.00
84 INT340365 Protein_catabolism of Clcn5 1 0.99 1.03 0 5.00
85 INT205576 Positive_regulation of Hnf1a 2 0.49 1.1 0 5.00
86 INT340363 Regulation of Clcn5 1 0.45 0.85 0 5.00
87 INT205583 Gene_expression of Hnf1b 1 0.59 2.09 0 5.00
88 INT340362 Gene_expression of Ocrl 3 0.67 2.27 0 5.00
89 INT205579 Positive_regulation of Gene_expression of Hnf1b 1 0.44 2.1 0 5.00
90 INT340371 Regulation of Tal 1 0.10 0.85 0 5.00
91 INT340370 Negative_regulation of Ocrl 1 0.43 2.31 0 5.00
92 INT340367 Regulation of Gene_expression of Ocrl 1 0.45 1.11 0 5.00
93 INT205582 Positive_regulation of Hnf1b 1 0.44 1.05 0 5.00
94 INT347732 Binding of Shc2 1 0.14 0.58 0 5.00
95 INT340368 Binding of Ocrl 1 0.37 2.61 0 5.00
96 INT340359 Binding of Clcn5 1 0.48 1.91 0 5.00
97 INT340374 Binding of Rabep1 1 0.05 0.61 0 5.00
98 INT205585 Regulation of Wnt4 1 0.45 0.7 0 5.00
99 INT340372 Negative_regulation of Protein_catabolism of Clcn5 1 0.43 1.07 0 5.00
100 INT205578 Negative_regulation of Wnt4 1 0.43 1.69 0 5.00
101 INT340361 Binding of Clcn4-2 1 0.30 0.82 0 5.00
102 INT340369 Negative_regulation of Tal 1 0.09 1.04 0 5.00
103 INT340364 Negative_regulation of Gene_expression of Ocrl 1 0.43 1.16 0 5.00
104 INT205581 Regulation of Negative_regulation of Wnt4 1 0.27 0.7 0 5.00
105 INT340366 Gene_expression of Clcn5 1 0.77 4.8 0 5.00
106 INT213398 Regulation of Gene_expression of SELPLG 2 0.04 0.23 0 5.00
107 INT205577 Positive_regulation of Gene_expression of Hnf1a 1 0.49 1.1 0 5.00
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