D:Disorders Of The Lacrimal System

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Disease Term
Synonyms Blepharitis, Dry Eye, Eye Dryness, Keratoconjunctivitis Sicca, Keratoconjunctivitis Sicca Kcs, Lachrymal, Lachrymation, LACRIMAL, Lacrimation, Meibomian Gland, STEVENS JOHNSON SYNDROME
Documents 753
Hot Single Events 200
Hot Interactions 14

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Disorders Of The Lacrimal System. They are ordered first by their relevance to Disorders Of The Lacrimal System and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT279635 Ar Regulation of Abpe 1 0.01 1.55 0 100.00
2 INT279633 Binding of Ar and Abpe 1 0.01 0.99 0 100.00
3 INT273774 Binding of GPER and RB1 1 0.01 0.45 0 100.00
4 INT354885 Amy1 Regulation of Gene_expression of Il10 1 0.03 1.41 0.13 93.92
5 INT325470 MMP3 Positive_regulation of MMP9 1 0.17 0.9 0.2 92.96
6 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 92.64
7 INT354888 Amy1 Regulation of Il10 1 0.02 1.41 0.13 92.64
8 INT166792 Binding of CD44 and HRAS 3 0.12 1.49 0.37 87.04
9 INT354889 Binding of TNF and Gtf3a 1 0.00 2.05 0 86.84
10 INT354890 Binding of TNF and Tnfsf13b 1 0.01 2.05 0 86.52
11 INT354887 Binding of Tnfsf13b and Gtf3a 1 0.01 2.05 0 86.52
12 INT279632 Positive_regulation of Binding of Ar and Nr4a1 1 0.01 0.86 0.03 84.48
13 INT279634 Binding of Ar and Nr4a1 1 0.01 0.85 0.03 84.08
14 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87 82.24
15 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34 75.76
16 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02 70.32
17 INT235969 Binding of Ighg1 and Nqo1 1 0.01 2.63 0.04 69.32
18 INT221068 Cd79a Regulation of Gene_expression of IgG 1 0.01 0.93 0.1 66.44
19 INT221067 Cd79a Regulation of IgG 1 0.01 0.93 0.1 66.44
20 INT221066 Cd79a Regulation of Gene_expression of Ighm 1 0.01 0.93 0.1 66.24
21 INT235968 NMO-IgG Positive_regulation of Nqo1 1 0.00 2.11 0.03 46.04
22 INT311432 Binding of TSHR and TAOK1 1 0.12 1.05 0.07 33.48
23 INT329841 Il4 Regulation of Hand1 1 0.04 0.87 0.18 31.56
24 INT329843 Il4 Regulation of Hand2 1 0.04 0.87 0.18 31.56
25 INT316674 Binding of CRP and SFTPD 1 0.16 2.02 0.59 28.00
26 INT311590 EGF Regulation of Gene_expression of CXCL10 1 0.23 0.51 0.43 15.36
27 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43 15.36
28 INT311591 CXCL10 Regulation of Gene_expression of EGF 1 0.23 0.51 0.43 15.36
29 INT311587 CXCL10 Regulation of Gene_expression of VEGFA 1 0.23 0.45 0.43 13.80
30 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2 5.00
31 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
32 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9 5.00
33 INT341336 Binding of Pepd and Nav1 1 0.07 0.92 1.3 5.00
34 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2 5.00
35 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2 5.00
36 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16 5.00
37 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93 5.00
38 INT289461 IRF6 Positive_regulation of ICAM1 1 0.08 0.61 0.91 5.00
39 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74 5.00
40 INT111080 Binding of CA1 and CA2 2 0.02 1.62 0.73 5.00
41 INT265463 CSPG4 Negative_regulation of Gene_expression of IL6 1 0.06 1.6 0.56 5.00
42 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56 5.00
43 INT235975 Binding of AQP4 and IgG 2 0.04 4.11 0.53 5.00
44 INT235956 Binding of Aqp4 and NMO-IgG 1 0.04 4.53 0.5 5.00
45 INT289464 Negative_regulation of IRF6 Positive_regulation of ICAM1 1 0.07 0.31 0.5 5.00
46 INT300956 Il4 Negative_regulation of IL8 1 0.02 0.37 0.48 5.00
47 INT289462 Negative_regulation of IRF6 Positive_regulation of IL1B 2 0.04 0.31 0.48 5.00
48 INT300960 Il4 Negative_regulation of IL1B 1 0.03 0.37 0.48 5.00
49 INT289463 IRF6 Positive_regulation of Localization of IL1B 1 0.05 0.52 0.48 5.00
50 INT300957 Binding of IL13 and Il4 1 0.01 0.58 0.48 5.00
51 INT300959 Il4 Negative_regulation of TNF 1 0.03 0.37 0.48 5.00
52 INT300955 Il4 Negative_regulation of Il6 1 0.03 0.37 0.48 5.00
53 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46 5.00
54 INT265465 CSPG4 Negative_regulation of Gene_expression of IL8 1 0.07 0.98 0.39 5.00
55 INT316675 Binding of CALR and SFTPD 1 0.35 0.96 0.37 5.00
56 INT316672 Binding of LRP1 and SFTPD 1 0.35 0.96 0.37 5.00
57 INT316676 Binding of CRX and SFTPD 1 0.05 0.65 0.33 5.00
58 INT235971 Positive_regulation of Binding of Nqo1 and NMO-IgG 1 0.00 1.86 0.32 5.00
59 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3 5.00
60 INT235977 Binding of AQP4 and Ighg1 1 0.03 1.31 0.3 5.00
61 INT187361 Binding of Gabrg1 and Kcnn3 1 0.36 0.13 0.3 5.00
62 INT235957 Binding of Mog and Bcr 1 0.02 1.13 0.29 5.00
63 INT235962 Binding of Bcr and Trav6-3 1 0.00 1.12 0.29 5.00
64 INT265467 HRAS Negative_regulation of Gene_expression of PTGS2 1 0.01 0.84 0.29 5.00
65 INT235966 Binding of Mog and Trav6-3 1 0.01 1.07 0.29 5.00
66 INT235959 Nqo1 Positive_regulation of Localization of Aqp4 1 0.02 1.39 0.26 5.00
67 INT300958 IL1B Positive_regulation of Il6 1 0.04 0.25 0.25 5.00
68 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 0.00 1.15 0.24 5.00
69 INT258521 EGFR Positive_regulation of MMP2 1 0.39 0.91 0.24 5.00
70 INT287794 Binding of IGHG3 and AIP 1 0.05 2.8 0.24 5.00
71 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24 5.00
72 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24 5.00
73 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24 5.00
74 INT235967 Binding of Ighm and Nqo1 1 0.00 1.45 0.23 5.00
75 INT258565 EGFR Positive_regulation of Meta 1 0.39 0.89 0.23 5.00
76 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21 5.00
77 INT306067 Binding of ADH5 and CYLD 1 0.02 3.13 0.19 5.00
78 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 5.00
79 INT276301 Binding of CCL21 and CXCL13 1 0.04 1.85 0.18 5.00
80 INT298641 PPARA Regulation of STAT3 1 0.23 0.98 0.16 5.00
81 INT247851 Negative_regulation of Aqp4 Negative_regulation of Positive_regulation of Narfl 1 0.09 1.78 0.15 5.00
82 INT298639 GDE1 Negative_regulation of AKT1 1 0.00 1.14 0.14 5.00
83 INT235961 Binding of Nqo1 and Aqp4 1 0.02 0.9 0.14 5.00
84 INT253929 Binding of Vcam1 and Cd99l2 1 0.00 0.61 0.13 5.00
85 INT227556 Ptgds Positive_regulation of Ppara 1 0.18 0.62 0.13 5.00
86 INT258527 Binding of BRAF and RET 1 0.21 1.49 0.11 5.00
87 INT209952 Binding of SNRNP70 and IGKV2-19 1 0.00 0.47 0.11 5.00
88 INT236467 MMP9 Negative_regulation of SNRPB 1 0.01 0.45 0.1 5.00
89 INT213421 Binding of CXCL2 and SET 1 0.11 0.17 0.1 5.00
90 INT213417 Binding of CCL7 and SET 1 0.11 0.17 0.1 5.00
91 INT213414 Binding of CXCL1 and SET 1 0.10 0.17 0.1 5.00
92 INT213415 Binding of CCL8 and SET 1 0.11 0.17 0.1 5.00
93 INT258522 Binding of DDR1 and RET 1 0.03 1.05 0.1 5.00
94 INT213420 Binding of IL6 and SET 1 0.10 0.17 0.1 5.00
95 INT213416 Binding of CCL2 and SET 1 0.11 0.17 0.1 5.00
96 INT276304 PRDM1 Regulation of TSC1 1 0.01 1.29 0.09 5.00
97 INT276391 Prdm1 Regulation of TSC1 1 0.00 1.29 0.09 5.00
98 INT265466 CSPG4 Regulation of Phosphorylation of TP53 1 0.09 0.15 0.09 5.00
99 INT298634 Binding of IL6 and STAT3 1 0.04 1.41 0.08 5.00
100 INT213418 Negative_regulation of FOXF1 Negative_regulation of Gene_expression of VCAM1 1 0.29 0.15 0.08 5.00
101 INT253930 IFNA1 Positive_regulation of Cdc42ep3 1 0.00 0.65 0.08 5.00
102 INT276375 Binding of Prdm1 and MIR9-1 1 0.12 1.12 0.08 5.00
103 INT276383 Binding of PRDM1 and Mirlet7a-1 1 0.39 1.12 0.08 5.00
104 INT220697 Binding of CHRNE and DBP 1 0.02 1.15 0.08 5.00
105 INT235964 Binding of Atp9a and Aqp4 1 0.01 0.55 0.08 5.00
106 INT276334 Binding of Prdm1 and Mirlet7a-1 1 0.12 1.13 0.08 5.00
107 INT276384 Binding of Mirlet7a-1 and MIR9-1 1 0.39 1.12 0.08 5.00
108 INT213419 Negative_regulation of FOXF1 Negative_regulation of Gene_expression of HGF 1 0.25 0.15 0.08 5.00
109 INT320659 Vsig2 Positive_regulation of Transcription of Nos2 1 0.07 0.65 0.07 5.00
110 INT329839 Negative_regulation of Tnfsf13b Negative_regulation of Gene_expression of Ighm 1 0.05 2.28 0.06 5.00
111 INT220698 Binding of CHRNE and SFTPA1 1 0.01 0.75 0.06 5.00
112 INT265459 Phosphorylation of TP53 Positive_regulation of Localization of CASP9 1 0.17 1.16 0.05 5.00
113 INT298638 IL6 Positive_regulation of IL6R 1 0.00 0.9 0.05 5.00
114 INT279889 Il6 Regulation of Socs3 1 0.21 0.17 0.05 5.00
115 INT236466 SNRPB Positive_regulation of NFKB2 1 0.00 0.21 0.05 5.00
116 INT276337 Timp1 Positive_regulation of Il10 1 0.01 0.76 0.05 5.00
117 INT265454 Phosphorylation of TP53 Positive_regulation of CASP9 1 0.17 1.16 0.05 5.00
118 INT235963 Snta1 Regulation of Gene_expression of Aqp4 1 0.41 0.23 0.05 5.00
119 INT298635 PPARA Negative_regulation of Localization of ZDHHC2 1 0.01 0.21 0.05 5.00
120 INT265456 CSPG4 Regulation of ROS1 1 0.05 0.24 0.04 5.00
121 INT247843 Narfl Regulation of Aqp4 1 0.04 1.07 0.04 5.00
122 INT276386 Gtf3a Regulation of PTPN6 1 0.00 0.86 0.04 5.00
123 INT298683 ecs Positive_regulation of Gene_expression of VEGFA 1 0.02 1.41 0.04 5.00
124 INT265451 CSPG4 Positive_regulation of RNGTT 1 0.03 0.24 0.04 5.00
125 INT276381 Timp1 Positive_regulation of CD44 1 0.07 0.72 0.04 5.00
126 INT265453 CSPG4 Regulation of Phosphorylation of ROS1 1 0.05 0.24 0.04 5.00
127 INT265457 CSPG4 Negative_regulation of IL6 1 0.06 0.24 0.04 5.00
128 INT265462 CSPG4 Negative_regulation of Positive_regulation of CASP9 1 0.07 1.2 0.04 5.00
129 INT276392 Timp1 Regulation of PTPN6 1 0.02 0.87 0.04 5.00
130 INT276376 Gtf3a Regulation of CD44 1 0.00 0.86 0.04 5.00
131 INT265461 CSPG4 Negative_regulation of Gene_expression of CASP9 1 0.06 1.2 0.04 5.00
132 INT247855 Positive_regulation of Narfl Regulation of Aqp4 1 0.04 2.93 0.04 5.00
133 INT276385 Timp1 Regulation of CD44 1 0.04 0.87 0.04 5.00
134 INT298637 ZDHHC2 Negative_regulation of Gene_expression of VEGFA 1 0.01 0.27 0.04 5.00
135 INT281733 LTK Regulation of IgG 1 0.00 1.37 0.03 5.00
136 INT276377 Binding of Lgals1 and KRT20 1 0.00 1.11 0.03 5.00
137 INT213422 MITF Negative_regulation of PROC 1 0.00 0.52 0.03 5.00
138 INT215810 Positive_regulation of Binding of Ca2 and Orai1 1 0.01 0.06 0.03 5.00
139 INT265464 CSPG4 Regulation of Gene_expression of TP53 1 0.09 0.23 0.03 5.00
140 INT298633 STAT3 Regulation of MCL1 1 0.04 0.85 0.03 5.00
141 INT276388 Il22 Positive_regulation of STAT3 1 0.03 1.3 0.03 5.00
142 INT276305 Binding of LGALS1 and KRT20 1 0.01 1.11 0.03 5.00
143 INT276389 Binding of Trp53 and KRT20 1 0.01 0.97 0.03 5.00
144 INT247856 Narfl Negative_regulation of Gene_expression of Uchl1 1 0.03 1 0.03 5.00
145 INT298640 IL6R Positive_regulation of STAT3 1 0.01 0.73 0.03 5.00
146 INT215811 Binding of Ca2 and Orai1 1 0.01 0.06 0.03 5.00
147 INT347577 Binding of MUC1 and MUC16 1 0.25 0.42 0 5.00
148 INT279885 Ctcf Regulation of H19 1 0.12 0 0 5.00
149 INT298684 ecs Positive_regulation of Gene_expression of KDR 1 0.01 1.2 0 5.00
150 INT247847 Narfl Positive_regulation of Positive_regulation of Casp3 1 0.02 0.79 0 5.00
151 INT247853 Positive_regulation of Narfl Negative_regulation of Gene_expression of Uchl1 1 0.03 0.54 0 5.00
152 INT247846 Positive_regulation of Narfl Positive_regulation of Positive_regulation of Ube4a 1 0.00 0.82 0 5.00
153 INT276382 Binding of CIB1 and Skp2 1 0.01 0.57 0 5.00
154 INT258524 IPMK Negative_regulation of KDR 2 0.00 1.98 0 5.00
155 INT279891 Shbdp1 Negative_regulation of PCDHB@ 1 0.01 0.09 0 5.00
156 INT265458 RNGTT Positive_regulation of Gene_expression of ROS1 1 0.08 0.88 0 5.00
157 INT265468 CSPG4 Positive_regulation of Gene_expression of ROS1 1 0.08 0.4 0 5.00
158 INT276300 TAT Regulation of Gene_expression of VEGFA 1 0.14 1.58 0 5.00
159 INT299232 Onc1 Regulation of Gene_expression of Aqp4 1 0.01 0.43 0 5.00
160 INT276390 Positive_regulation of CD40 Positive_regulation of Gene_expression of Pdcd1 1 0.01 1.06 0 5.00
161 INT276378 CD40 Positive_regulation of Gene_expression of Pdcd1 1 0.01 1.06 0 5.00
162 INT276387 ALK Positive_regulation of Gene_expression of Il22ra1 1 0.00 1.55 0 5.00
163 INT328626 Binding of TBCE and MUC16 1 0.15 0.79 0 5.00
164 INT273136 Binding of CHED1 and VSX1 1 0.15 0.12 0 5.00
165 INT279886 Shbdp1 Negative_regulation of Pcdhb1 1 0.10 0.09 0 5.00
166 INT327845 Binding of Aqp9 and Ooep 1 0.00 0 0 5.00
167 INT144032 STAT3 Regulation of BCL2 2 0.07 0.86 0 5.00
168 INT258523 Positive_regulation of RAF1 Positive_regulation of Phosphorylation of GSK 1 0.19 0.64 0 5.00
169 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0 5.00
170 INT276380 Binding of PIM1 and Trp53 1 0.01 0.66 0 5.00
171 INT247848 Narfl Negative_regulation of Uchl1 1 0.03 0.74 0 5.00
172 INT328627 Binding of LGALS3 and MUC16 1 0.04 0.73 0 5.00
173 INT276379 Binding of SKP2 and Cdkn1b 1 0.02 0.57 0 5.00
174 INT279884 Nipbl Regulation of Transcription of Pcdhb1 1 0.25 0.05 0 5.00
175 INT276303 Negative_regulation of AKT1 Negative_regulation of CCND1 1 0.01 0.58 0 5.00
176 INT299234 Onc1 Negative_regulation of Thy1 1 0.02 0.16 0 5.00
177 INT279892 Shbdp1 Negative_regulation of Gene_expression of PCDHB@ 1 0.01 0.09 0 5.00
178 INT247857 Narfl Positive_regulation of Gene_expression of Gfap 1 0.07 0.81 0 5.00
179 INT265460 CSPG4 Negative_regulation of Positive_regulation of CASP3 1 0.06 0.27 0 5.00
180 INT247888 Narfl Positive_regulation of CASP3 1 0.00 0.77 0 5.00
181 INT247850 Positive_regulation of Narfl Regulation of Ube4a 1 0.00 1.86 0 5.00
182 INT276336 Skp2 Regulation of Cdkn1b 1 0.00 0.57 0 5.00
183 INT258526 IPMK Negative_regulation of BRAF 1 0.01 1.11 0 5.00
184 INT276374 Skp2 Regulation of Protein_catabolism of CIB1 1 0.00 0.58 0 5.00
185 INT235960 Binding of Aqp4 and H47 1 0.01 0.13 0 5.00
186 INT236468 TP53 Positive_regulation of Protein_catabolism of SNRPB 1 0.00 0.52 0 5.00
187 INT298632 STAT3 Positive_regulation of MIR21 1 0.03 0.84 0 5.00
188 INT276335 Binding of Cdkn1b and Skp2 1 0.00 0.57 0 5.00
189 INT276333 Binding of Il10rb and Il22ra1 1 0.00 1.25 0 5.00
190 INT265452 Binding of TNFRSF10B and RNU5A-1 1 0.05 0.67 0 5.00
191 INT276302 Binding of SKP2 and CIB1 1 0.03 0.57 0 5.00
192 INT209951 Binding of KCNJ13 and SNRNP70 1 0.00 0 0 5.00
193 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0 5.00
194 INT258525 IPMK Negative_regulation of DDR1 2 0.00 1.97 0 5.00
195 INT247849 Edn1 Regulation of Gene_expression of Aqp4 1 0.12 1.05 0 5.00
196 INT279888 Binding of Rec8 and Nipbl 1 0.01 0.81 0 5.00
197 INT247852 Narfl Positive_regulation of Localization of Aqp4 1 0.08 0.81 0 5.00
198 INT276393 Skp2 Regulation of CIB1 1 0.00 0.57 0 5.00
199 INT265455 CSPG4 Negative_regulation of Positive_regulation of CASP8 1 0.04 0.27 0 5.00
200 INT299233 Onc1 Regulation of Gene_expression of Aqp9 1 0.01 0.19 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Disorders Of The Lacrimal System. They are ordered first by their pain relevance and then by number of times they were reported in Disorders Of The Lacrimal System. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT265440 Gene_expression of Abpe 2 0.19 10.64 1.07 100.00
2 INT279626 Regulation of Gene_expression of Abpe 1 0.13 3.24 0.38 100.00
3 INT279629 Positive_regulation of Abpe 1 0.20 2.22 0.12 100.00
4 INT170051 Positive_regulation of Gene_expression of Gopc 150 0.43 56.75 16.93 100.00
5 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 100.00
6 INT279631 Negative_regulation of Abpe 1 0.12 1.29 0.04 100.00
7 INT85861 Localization of Abpe 6 0.21 1.33 0.66 100.00
8 INT279630 Regulation of Abpe 1 0.13 1.07 0.09 100.00
9 INT797 Regulation of Penk 812 0.62 111.13 542.24 100.00
10 INT279625 Positive_regulation of Gene_expression of Abpe 1 0.14 0.76 0 100.00
11 INT279627 Transcription of Abpe 1 0.20 1.38 0.2 100.00
12 INT46101 Regulation of TBCE 2 0.11 1.53 0.43 100.00
13 INT205189 Gene_expression of TBCE 12 0.25 9.67 1.19 100.00
14 INT274092 Negative_regulation of Gene_expression of TBCE 1 0.08 1.17 0.03 100.00
15 INT257447 Binding of TBCE 4 0.08 4.68 0.66 100.00
16 INT337504 Localization of Prol1 1 0.58 0.49 0 100.00
17 INT33845 Binding of GPER 20 0.36 5.61 1.81 100.00
18 INT205187 Localization of TBCE 3 0.14 4.11 2.47 100.00
19 INT54615 Gene_expression of GPER 25 0.75 8.23 2.27 100.00
20 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 100.00
21 INT15495 Positive_regulation of Negative_regulation of MET 1 0.45 0.49 0.07 100.00
22 INT32598 Localization of SMR3A 2 0.63 0.66 0.15 100.00
23 INT337513 Localization of SMR3B 1 0.50 0.16 0 100.00
24 INT337505 Localization of Smr3a 1 0.05 0.17 0 100.00
25 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31 99.98
26 INT7524 Localization of Kitl 9 0.74 3.45 5.49 99.98
27 INT160766 Localization of HSPA9 2 0.78 1.84 0.26 99.96
28 INT159988 Localization of Ctsk 5 0.70 2.9 0.74 99.82
29 INT160264 Localization of Fn1 10 0.40 3.95 1.51 99.82
30 INT245259 Localization of Mmp3 6 0.68 4.49 1.58 99.82
31 INT89971 Localization of Sparc 10 0.80 10.25 1.85 99.82
32 INT13823 Gene_expression of Egf 97 0.78 39.99 12.99 99.76
33 INT123520 Gene_expression of Ar 12 0.32 6.98 0.25 99.68
34 INT44066 Gene_expression of Ltf 20 0.77 15.09 4.57 99.68
35 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 99.68
36 INT272794 Positive_regulation of Positive_regulation of IGHG3 3 0.04 2.84 0.17 99.68
37 INT99610 Localization of MMP9 126 0.79 48.46 32.67 99.68
38 INT34487 Localization of MMP2 56 0.81 31.41 23.61 99.68
39 INT9220 Gene_expression of Ighg1 125 0.77 85.74 15.92 99.60
40 INT134296 Positive_regulation of Ptges2 20 0.19 14.85 3.8 99.58
41 INT9660 Regulation of TNF 363 0.62 312.94 139.99 99.58
42 INT265449 Gene_expression of Aire 10 0.67 9.18 1.8 99.56
43 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34 99.54
44 INT213363 Regulation of Gene_expression of Ar 2 0.11 1.63 0.03 99.52
45 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.48
46 INT93738 Gene_expression of Tnfrsf1a 63 0.74 57.66 23.09 99.48
47 INT93739 Positive_regulation of Gene_expression of Tnfrsf1a 11 0.66 11.17 4.44 99.48
48 INT194993 Binding of RB1 15 0.37 10.96 0.4 99.44
49 INT235939 Gene_expression of Aqp5 8 0.45 4.7 1.06 99.44
50 INT21901 Negative_regulation of Egf 25 0.58 10.46 4.99 99.42
51 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 99.38
52 INT3165 Gene_expression of LYZ 25 0.65 16.72 5.16 99.36
53 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 99.32
54 INT325457 Negative_regulation of Binding of TLR2 1 0.04 1.3 0.43 99.20
55 INT150540 Binding of TLR2 50 0.45 35.86 10.43 99.20
56 INT273783 Regulation of Gene_expression of RB1 1 0.29 0.67 0 99.16
57 INT20371 Gene_expression of Cd8a 125 0.60 67.59 8.97 99.14
58 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 99.12
59 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 99.12
60 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 99.12
61 INT327837 Negative_regulation of Aqp5 1 0.18 1.48 0.07 99.12
62 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 99.12
63 INT198121 Gene_expression of Aqp9 19 0.77 5.67 0.12 99.08
64 INT12270 Gene_expression of Chrna2 11 0.67 5.47 3.06 99.04
65 INT68244 Positive_regulation of Ighg1 60 0.61 48.86 5.01 99.02
66 INT25502 Gene_expression of RERE 6 0.53 1.74 0.32 98.98
67 INT4922 Negative_regulation of MET 19 0.57 13.97 3.7 98.92
68 INT279628 Negative_regulation of Ar 5 0.04 6.1 0.25 98.80
69 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 98.80
70 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 98.72
71 INT120062 Binding of AIP 4 0.42 28.86 3.91 98.64
72 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 98.64
73 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 98.64
74 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 98.64
75 INT144168 Gene_expression of CCL1 7 0.13 5.69 2.45 98.60
76 INT265435 Negative_regulation of Muc19 1 0.19 1.3 0.25 98.40
77 INT21076 Negative_regulation of Muc5ac 8 0.42 2.48 2.78 98.40
78 INT57526 Regulation of Ltf 8 0.45 2.73 0.56 98.40
79 INT32579 Binding of C4B 14 0.36 14.99 7.79 98.40
80 INT216065 Localization of C4B 2 0.21 2.86 2.01 98.40
81 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79 98.22
82 INT156671 Gene_expression of Vcsa1 22 0.75 23.32 1.69 98.20
83 INT270341 Positive_regulation of Gene_expression of Vcsa1 3 0.57 1.12 0.29 98.20
84 INT6480 Positive_regulation of IL1RN 59 0.69 33.7 16.66 98.12
85 INT242745 Regulation of FANCE 2 0.28 1.98 0.66 98.12
86 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 98.08
87 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 98.06
88 INT150022 Positive_regulation of Il17a 69 0.64 70.04 21.87 98.00
89 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 98.00
90 INT124954 Gene_expression of Egfr 26 0.75 15.08 3.12 97.96
91 INT258009 Positive_regulation of DCR 2 0.34 1.05 0 97.88
92 INT226028 Gene_expression of Trove2 4 0.65 9.97 0.54 97.88
93 INT106960 Gene_expression of Chrm3 15 0.69 6.29 0.96 97.88
94 INT201347 Negative_regulation of Gene_expression of Chrm3 4 0.30 2.48 0.31 97.88
95 INT354861 Negative_regulation of Gene_expression of Trove2 1 0.41 1.4 0.04 97.88
96 INT66924 Positive_regulation of Transcription of Il6 18 0.68 11.8 3.53 97.76
97 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 97.76
98 INT49985 Transcription of Il6 62 0.72 40.13 20.29 97.76
99 INT236335 Gene_expression of SFTPD 26 0.75 15.92 4.59 97.72
100 INT50255 Regulation of Cd4 39 0.49 29.73 6.77 97.60
101 INT198453 Negative_regulation of MUC5AC 12 0.58 12.96 1.38 97.60
102 INT12339 Localization of IL8 437 0.81 251.87 117.39 97.48
103 INT12082 Localization of IL6 365 0.81 241.78 105.78 97.48
104 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 97.48
105 INT72565 Localization of IL1RN 45 0.80 23.59 13.17 97.48
106 INT311593 Localization of Cx3cl1 3 0.49 1.99 1.69 97.48
107 INT64609 Negative_regulation of PLXNA3 5 0.57 3.64 1.94 97.40
108 INT279624 Negative_regulation of Gpx3 2 0.18 0.67 0 97.16
109 INT238524 Localization of MGS 1 0.44 1.59 0.05 97.16
110 INT227557 Binding of FAM155B 1 0.08 3.66 0.45 97.00
111 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78 96.96
112 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 96.92
113 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 96.92
114 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 96.92
115 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47 96.92
116 INT39414 Gene_expression of SNRPB 37 0.59 14.07 2.52 96.84
117 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 96.84
118 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 96.84
119 INT12324 Positive_regulation of PRTN3 26 0.70 18.82 4.55 96.64
120 INT85655 Gene_expression of Crhr1 17 0.68 9.34 6.31 96.52
121 INT122950 Binding of BAK1 16 0.41 12.85 0.31 96.52
122 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 96.44
123 INT176607 Gene_expression of Cx3cl1 27 0.75 19.51 11.32 96.44
124 INT71359 Regulation of Dct 2 0.21 1.77 0.13 96.40
125 INT179213 Gene_expression of Aqp3 10 0.63 5.13 0.77 96.40
126 INT9012 Localization of Vip 283 0.81 31.71 106.16 96.28
127 INT311605 Positive_regulation of AATF 5 0.06 6.72 1.05 96.12
128 INT17451 Positive_regulation of Tst 23 0.67 8.85 9.52 96.08
129 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 96.04
130 INT92237 Positive_regulation of Gene_expression of CXCL10 43 0.70 43.67 13.65 96.04
131 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63 95.76
132 INT87844 Binding of IL1RN 40 0.41 24.37 11.92 95.76
133 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46 95.68
134 INT243079 Regulation of Ar 3 0.08 1.22 0.12 95.48
135 INT10834 Binding of IL8 65 0.48 41.66 16.53 95.44
136 INT29210 Negative_regulation of Terc 7 0.37 1.6 7.21 95.40
137 INT1352 Localization of Acot1 728 0.80 73.01 296.01 95.32
138 INT3766 Positive_regulation of Localization of Acot1 192 0.69 21.8 85.35 95.32
139 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73 95.16
140 INT63113 Positive_regulation of HRAS 30 0.67 22.85 4.28 94.88
141 INT70850 Positive_regulation of Transcription of Nos2 30 0.70 18.95 9.68 94.84
142 INT49266 Positive_regulation of Arigg4 37 0.47 53.79 11.2 94.80
143 INT21662 Gene_expression of Cpz 4 0.51 1.14 3.36 94.80
144 INT182676 Transcription of C4B 1 0.31 4.82 3.66 94.72
145 INT354863 Regulation of Localization of Cacna1s 1 0.03 2.08 0 94.72
146 INT354859 Localization of Cacna1s 1 0.05 3.15 0.15 94.72
147 INT1166 Negative_regulation of Dbh 56 0.59 12.54 28.26 94.64
148 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 94.52
149 INT71360 Positive_regulation of Dct 1 0.36 0.76 0.09 94.52
150 INT9377 Positive_regulation of Positive_regulation of TRPV1 43 0.70 15.81 24.47 94.52
151 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82 94.48
152 INT61953 Transcription of Nos2 101 0.72 46.64 25.49 94.40
153 INT89784 Regulation of Transcription of Nos2 14 0.42 8.39 4.24 94.40
154 INT262474 Gene_expression of Aqp6 26 0.77 2.08 2.49 94.36
155 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 94.28
156 INT10462 Gene_expression of Tcrb 7 0.65 2.34 0.13 94.20
157 INT12837 Binding of SIGMAR1 57 0.48 5.31 15.49 93.92
158 INT41673 Gene_expression of Amy1 2 0.30 2.41 0.21 93.92
159 INT61891 Positive_regulation of Binding of SIGMAR1 2 0.32 0.34 0.39 93.92
160 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 93.84
161 INT9383 Localization of TRPV1 98 0.81 33.23 46.24 93.64
162 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 93.36
163 INT39416 Gene_expression of Cd79a 81 0.64 45.17 6.08 93.36
164 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 93.32
165 INT235944 Binding of TROVE2 1 0.08 2.43 0.12 93.32
166 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 93.08
167 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 93.00
168 INT315711 Regulation of Localization of lg 1 0.11 0.25 0.04 92.92
169 INT161960 Regulation of lg 5 0.26 1.18 2.84 92.92
170 INT120828 Localization of CXCL10 29 0.68 18.01 12.17 92.76
171 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 92.48
172 INT315710 Localization of lg 7 0.32 1.72 0.6 92.32
173 INT311604 Gene_expression of AATF 3 0.06 2.9 0.55 92.32
174 INT158764 Binding of SPINK5 7 0.35 8.84 0.37 92.00
175 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 91.96
176 INT94335 Positive_regulation of CXCL10 71 0.58 50.69 23 91.88
177 INT311602 Positive_regulation of Binding of CXCL10 1 0.38 2.79 0.57 91.88
178 INT165821 Positive_regulation of Aqp4 27 0.70 24.37 3.22 91.84
179 INT1129 Binding of Car2 69 0.35 14.01 9.2 91.60
180 INT148085 Binding of CXCL10 14 0.32 10.22 3.81 91.48
181 INT83292 Gene_expression of MIP 35 0.75 25.22 10.14 91.16
182 INT119506 Negative_regulation of Egfr 32 0.55 23.75 3.67 91.12
183 INT82885 Gene_expression of Mip 7 0.65 7.89 2.76 90.96
184 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 90.88
185 INT158601 Negative_regulation of lg 2 0.12 0.37 0.12 90.72
186 INT265442 Positive_regulation of Gene_expression of Aire 1 0.43 1.32 0.27 90.72
187 INT265444 Negative_regulation of Aire 1 0.37 5.68 1.3 90.52
188 INT340759 Gene_expression of AZGP1 1 0.54 5.4 0.17 90.48
189 INT265438 Gene_expression of Sprr1b 1 0.72 6.76 1.33 90.40
190 INT265446 Negative_regulation of Gene_expression of Sprr1b 1 0.40 1.9 0.36 90.40
191 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 90.32
192 INT60690 Positive_regulation of Gene_expression of Il12a 69 0.63 41.41 20.85 90.32
193 INT227549 Gene_expression of Tshr 4 0.35 4.32 0.24 90.28
194 INT33517 Gene_expression of TSHR 20 0.71 14.65 1.45 90.16
195 INT265433 Positive_regulation of Sprr1b 1 0.64 3.76 0.53 90.04
196 INT326369 Gene_expression of Cntn2 2 0.25 1.34 0.2 89.96
197 INT12388 Negative_regulation of Crhr1 17 0.59 9.47 3.33 89.92
198 INT73252 Positive_regulation of Mthfd1 124 0.59 59.48 18.35 89.88
199 INT157816 Positive_regulation of Positive_regulation of Mthfd1 5 0.33 3.73 1.93 89.88
200 INT213967 Positive_regulation of Localization of Mthfd1 4 0.30 2.52 0.46 89.88
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