D:Diverticulum

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Disease Term
Synonyms DIVERTICULA, DIVERTICULOSIS
Documents 947
Hot Single Events 35
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Diverticulum. They are ordered first by their relevance to Diverticulum and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT97314 Binding of ETFA and KRT1 1 0.07 0.75 0.08 82.60
2 INT296372 Binding of IDUA and ACD 1 0.03 2.72 0.23 76.92
3 INT296945 ADIPOQ Negative_regulation of TNF 1 0.03 1.13 0.4 5.00
4 INT198382 Binding of AR and SRD5A1 2 0.06 0.84 0.17 5.00
5 INT272441 Binding of IFNA2 and Slc11a1 1 0.02 0.97 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Diverticulum. They are ordered first by their pain relevance and then by number of times they were reported in Diverticulum. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT2117 Regulation of VSX1 15 0.30 3.38 3.38 100.00
2 INT103585 Gene_expression of MANEA 4 0.75 2.12 0.31 99.60
3 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 98.70
4 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 98.16
5 INT8773 Gene_expression of HBG1 58 0.76 37.6 4.59 97.60
6 INT108710 Gene_expression of HAL 36 0.58 14.75 2.16 97.60
7 INT1921 Gene_expression of CEACAM7 47 0.78 43.23 2.53 97.56
8 INT30 Gene_expression of Gast 158 0.78 99 41.45 97.44
9 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33 97.04
10 INT1922 Positive_regulation of CEACAM7 32 0.70 33.31 2.72 95.12
11 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 94.72
12 INT1309 Positive_regulation of Localization of Gnrhr 152 0.69 24.25 81.56 94.72
13 INT343032 Localization of Lbt1 1 0.18 1.18 0.33 94.52
14 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 93.76
15 INT28084 Positive_regulation of VIM 49 0.67 35.12 5.15 93.40
16 INT186998 Negative_regulation of Gene_expression of KIT 20 0.43 16.77 0.46 92.76
17 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 92.40
18 INT79425 Gene_expression of SMN1 42 0.65 36.37 6.1 92.40
19 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 91.44
20 INT84464 Gene_expression of DPP4 101 0.78 56.15 17.53 91.32
21 INT343034 Gene_expression of Lbt1 1 0.17 1.31 0.3 91.32
22 INT182807 Localization of Cuzd1 2 0.49 1.38 0.14 90.88
23 INT341438 Positive_regulation of Slc25a16 1 0.32 0.9 0 90.32
24 INT3559 Negative_regulation of Localization of Gnrhr 73 0.58 18.89 26.41 90.32
25 INT15229 Positive_regulation of CNDP1 21 0.69 15.86 4.06 90.00
26 INT120722 Gene_expression of TYMP 35 0.75 19.26 1.31 89.04
27 INT2093 Gene_expression of GAST 50 0.78 32.32 7.98 88.56
28 INT211375 Regulation of Gene_expression of TYMP 2 0.43 2.44 0.22 87.52
29 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 86.88
30 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19 83.92
31 INT233108 Gene_expression of ADAM2 1 0.17 1.32 0.17 83.92
32 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07 83.20
33 INT57070 Protein_catabolism of VUR 19 0.99 18.75 0.76 81.20
34 INT156595 Gene_expression of CDX2 10 0.69 7.8 0.25 81.08
35 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 81.08
36 INT10048 Positive_regulation of SERPINA1 11 0.68 8.59 2.43 79.08
37 INT37722 Gene_expression of NCAM1 103 0.75 81.57 14.18 77.28
38 INT38990 Negative_regulation of IDUA 12 0.59 5.04 1.33 76.92
39 INT84826 Negative_regulation of ACD 6 0.50 4.02 0.55 76.92
40 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 76.84
41 INT251830 Binding of TYMP 2 0.13 4.36 0.37 76.80
42 INT341437 Gene_expression of Slc25a16 1 0.47 2.39 0.3 76.16
43 INT97315 Positive_regulation of LGALS3 2 0.58 1.6 0.66 75.96
44 INT25465 Positive_regulation of ISL1 6 0.15 3.59 0.26 74.52
45 INT172809 Gene_expression of ISL1 33 0.40 21.63 1.12 74.32
46 INT296947 Binding of ISM1 1 0.15 4.54 0.46 65.92
47 INT296385 Binding of IDUA 12 0.39 20.73 0.93 64.84
48 INT22237 Localization of NTS 14 0.75 5.5 2.77 62.28
49 INT329191 Negative_regulation of Localization of NTS 1 0.08 0.48 0.2 62.28
50 INT84250 Positive_regulation of IDUA 8 0.56 15.89 0.62 60.16
51 INT343031 Positive_regulation of Gene_expression of Lbt1 1 0.12 0.12 0 59.12
52 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 58.88
53 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 58.48
54 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 58.28
55 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 58.20
56 INT140929 Gene_expression of Cd40 9 0.72 8.76 2.88 57.00
57 INT237383 Positive_regulation of Protein_catabolism of VUR 3 0.50 4.25 0.04 56.40
58 INT32900 Negative_regulation of Positive_regulation of Chat 3 0.43 1.91 1.45 55.44
59 INT4851 Positive_regulation of Chat 53 0.70 9.21 15.11 55.44
60 INT183560 Binding of GABRB3 12 0.23 2.59 3.77 54.56
61 INT134902 Positive_regulation of Tymp 11 0.37 3.06 0.53 54.56
62 INT6381 Negative_regulation of Chat 51 0.59 19.68 15.86 53.36
63 INT8629 Positive_regulation of COL7A1 72 0.69 40.66 12.09 52.08
64 INT343033 Positive_regulation of Lbt1 1 0.12 0.95 0.34 51.08
65 INT138556 Positive_regulation of TYMP 23 0.58 12.9 0.28 49.60
66 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 49.40
67 INT337584 Positive_regulation of LYPLA2P1 1 0.49 0.95 0.07 49.40
68 INT287309 Positive_regulation of ENO1 5 0.59 5.67 1.52 48.92
69 INT48407 Positive_regulation of Gene_expression of Icam1 61 0.70 57.91 21.54 47.24
70 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 46.88
71 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 39.60
72 INT20633 Positive_regulation of Gene_expression of LDHA 15 0.49 15.94 1.42 39.60
73 INT296948 Negative_regulation of ISM1 1 0.16 1.04 0.14 38.24
74 INT81211 Transcription of Rac1 4 0.54 1.05 0.89 35.88
75 INT138555 Negative_regulation of Tymp 3 0.39 3.31 0.74 35.28
76 INT287307 Binding of ENO1 9 0.48 11.24 2.51 33.00
77 INT129565 Negative_regulation of Cuzd1 5 0.43 0.65 1.24 30.00
78 INT17817 Binding of VUR 41 0.48 46.85 0.95 28.16
79 INT66002 Binding of LAMC2 9 0.47 4.5 2.54 26.80
80 INT137382 Negative_regulation of Gene_expression of KRT20 22 0.58 12.29 1.29 24.08
81 INT216395 Negative_regulation of Gene_expression of KRT7 4 0.41 3.57 0.16 24.08
82 INT194023 Gene_expression of RQCD1 3 0.52 3.99 0.12 21.84
83 INT89 Positive_regulation of Gast 187 0.70 80.49 42.07 19.56
84 INT9884 Localization of CD79A 41 0.78 21.75 3.06 18.40
85 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 16.00
86 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 15.36
87 INT325005 Positive_regulation of Gene_expression of SMUG1 3 0.25 0.93 1.23 15.36
88 INT162393 Gene_expression of SMUG1 58 0.75 38.78 7.7 14.96
89 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 14.80
90 INT158796 Positive_regulation of SMUG1 67 0.70 38.97 8.98 13.32
91 INT115982 Positive_regulation of KRT7 18 0.50 19.81 1.14 13.08
92 INT122813 Binding of Krt20 11 0.32 13.77 0.88 12.24
93 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 11.76
94 INT9383 Localization of TRPV1 98 0.81 33.23 46.24 11.76
95 INT226838 Transcription of Isl1 2 0.28 0.36 0.6 9.56
96 INT311240 Negative_regulation of Gene_expression of DPP4 6 0.59 3.43 0.13 9.28
97 INT33612 Binding of NTS 16 0.46 4.65 6 8.68
98 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 6.52
99 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 5.00
100 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
101 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 5.00
102 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 5.00
103 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 5.00
104 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
105 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 5.00
106 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 5.00
107 INT1114 Localization of Ins1 748 0.80 192.95 165.48 5.00
108 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
109 INT90 Localization of Gast 400 0.81 137.67 113 5.00
110 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 5.00
111 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7 5.00
112 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 5.00
113 INT3034 Localization of Ngf 126 0.81 50.81 72.84 5.00
114 INT2055 Regulation of Gnrh1 185 0.62 23.65 71.26 5.00
115 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
116 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15 5.00
117 INT7134 Localization of KNG1 127 0.79 65.73 67.97 5.00
118 INT2056 Negative_regulation of Gnrh1 175 0.59 33.43 63.32 5.00
119 INT96622 Localization of Trpv1 110 0.81 59.82 63.25 5.00
120 INT4891 Transcription of Calca 81 0.72 35.27 53.75 5.00
121 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64 5.00
122 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 5.00
123 INT2197 Gene_expression of Gnrh1 184 0.78 40.04 50.57 5.00
124 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 5.00
125 INT2275 Negative_regulation of Localization of Ins1 183 0.59 51.02 44.94 5.00
126 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
127 INT5454 Localization of CRH 124 0.79 79.18 41.53 5.00
128 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24 5.00
129 INT326 Gene_expression of Gnrhr 105 0.76 35.87 34.93 5.00
130 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 5.00
131 INT7082 Gene_expression of CRH 180 0.78 64.66 31.74 5.00
132 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
133 INT2408 Regulation of CCK 37 0.61 10.01 26.66 5.00
134 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
135 INT825 Negative_regulation of ADRA1D 54 0.58 20.25 22.78 5.00
136 INT7383 Localization of VIP 53 0.81 17.7 22.65 5.00
137 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52 5.00
138 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
139 INT3593 Gene_expression of ADRA1D 70 0.75 29.48 20.87 5.00
140 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 5.00
141 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 5.00
142 INT7253 Negative_regulation of Localization of Gast 70 0.59 21.06 20.06 5.00
143 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 5.00
144 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 5.00
145 INT90937 Negative_regulation of Gene_expression of Trpv1 34 0.59 22.74 18.12 5.00
146 INT27670 Negative_regulation of Ace 122 0.57 79.21 18.08 5.00
147 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 5.00
148 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83 5.00
149 INT92354 Localization of ESR1 77 0.75 33.04 15.51 5.00
150 INT7523 Regulation of ADRA1D 42 0.45 11.63 14.52 5.00
151 INT18773 Localization of ALB 117 0.80 69.18 13.8 5.00
152 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 5.00
153 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
154 INT86646 Positive_regulation of SCN10A 71 0.69 50.61 13.24 5.00
155 INT1827 Gene_expression of Aap 11 0.67 9.37 12.66 5.00
156 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 5.00
157 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 5.00
158 INT8548 Gene_expression of HP 86 0.77 47.62 11.94 5.00
159 INT32203 Negative_regulation of Crp 48 0.58 32.77 11.89 5.00
160 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 5.00
161 INT7411 Localization of FGFR3 40 0.78 4.77 10.24 5.00
162 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1 5.00
163 INT4808 Gene_expression of LTC4S 37 0.73 18.36 9.62 5.00
164 INT132036 Negative_regulation of DPP4 126 0.59 63.24 9.51 5.00
165 INT75997 Positive_regulation of Localization of Ngf 14 0.69 7.78 9.41 5.00
166 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97 5.00
167 INT55537 Positive_regulation of Coq10a 22 0.58 8.17 8.33 5.00
168 INT113987 Localization of IK 29 0.23 16.73 8.25 5.00
169 INT67037 Gene_expression of Sod1 121 0.78 59.32 7.99 5.00
170 INT87139 Negative_regulation of Positive_regulation of Il6 18 0.59 10.65 7.76 5.00
171 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 5.00
172 INT20922 Positive_regulation of Localization of CRH 18 0.67 11.12 6.79 5.00
173 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 5.00
174 INT5871 Binding of IFNA2 38 0.48 20.35 6.46 5.00
175 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 5.00
176 INT38672 Binding of KRT20 69 0.39 48.01 6.31 5.00
177 INT16568 Positive_regulation of HTR3A 14 0.67 4.82 6.01 5.00
178 INT25123 Negative_regulation of COL7A1 42 0.58 19.98 5.96 5.00
179 INT4587 Negative_regulation of Serping1 32 0.47 19.11 5.92 5.00
180 INT57502 Positive_regulation of Gene_expression of CRH 30 0.70 23.37 5.7 5.00
181 INT11480 Positive_regulation of Localization of KNG1 15 0.30 6.39 5.5 5.00
182 INT17056 Gene_expression of DLD 37 0.57 13.15 5.47 5.00
183 INT36893 Negative_regulation of Coq10a 36 0.55 22.24 5.47 5.00
184 INT156794 Gene_expression of CISH 41 0.58 23.09 5.03 5.00
185 INT18011 Positive_regulation of HP 60 0.50 31.88 4.75 5.00
186 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72 5.00
187 INT137332 Positive_regulation of Gene_expression of Sod1 41 0.70 19.8 4.69 5.00
188 INT8336 Transcription of Gnrh1 22 0.71 4.37 4.69 5.00
189 INT203443 Gene_expression of Isl1 27 0.67 11.12 4.65 5.00
190 INT67144 Gene_expression of Cd44 17 0.76 8.94 4.48 5.00
191 INT26404 Positive_regulation of ATM 15 0.49 10.94 4.39 5.00
192 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19 5.00
193 INT61316 Gene_expression of Coq10a 59 0.73 32.81 3.95 5.00
194 INT10146 Negative_regulation of Vwf 27 0.40 17.11 3.69 5.00
195 INT13451 Positive_regulation of DPP4 23 0.68 9.33 3.62 5.00
196 INT139366 Gene_expression of PROM1 98 0.77 67.84 3.39 5.00
197 INT34809 Gene_expression of Ec 36 0.15 15.7 3.24 5.00
198 INT60554 Binding of Coq10a 30 0.40 7.99 3.02 5.00
199 INT16616 Negative_regulation of SRD5A1 44 0.57 34.81 2.96 5.00
200 INT3463 Gene_expression of Igfals 21 0.39 21.1 2.93 5.00
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