D:Double Outlet Right Ventricle

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Disease Term
Synonyms Anomaly Taussig Bing, DOUBLE OUTLET RIGHT VENTRICLE NONCOMMITTED VSD, Double Outlet Right Ventricle Subaortic Vsd, Double Outlet Right Ventricle Subpulmonary Vsd, TAUSSIG BING ANOMALY
Documents 40
Hot Single Events 8
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Double Outlet Right Ventricle. They are ordered first by their relevance to Double Outlet Right Ventricle and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT273289 Binding of Psen2 and Ryr2 1 0.27 4.53 0 98.88
2 INT354544 Avp Positive_regulation of ADCY1 1 0.24 2.23 0.22 5.00
3 INT126944 Binding of PKD2 and Pkd1 2 0.08 2.09 0.19 5.00
4 INT273288 Psen1 Regulation of Prdx2 1 0.01 0.7 0.06 5.00
5 INT273287 Binding of Atp2a2 and Pln 1 0.08 0.26 0 5.00
6 INT273290 Binding of Atp2a2 and Tlx2 1 0.05 0.26 0 5.00
7 INT273291 Atp2a2 Regulation of Car2 1 0.10 0.31 0 5.00
8 INT273286 Tlx2 Regulation of Car2 1 0.06 0.31 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Double Outlet Right Ventricle. They are ordered first by their pain relevance and then by number of times they were reported in Double Outlet Right Ventricle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT219581 Binding of Ryr2 2 0.27 4.54 0 95.76
2 INT163544 Binding of Psen1 40 0.36 15.28 2.42 93.52
3 INT78649 Binding of Psen2 7 0.36 5.9 0.73 93.20
4 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83 83.52
5 INT65500 Gene_expression of App 605 0.78 429.94 98.31 83.52
6 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19 83.52
7 INT47712 Positive_regulation of App 135 0.69 101.38 28.94 82.76
8 INT193856 Localization of Psen1 19 0.73 9.79 0.41 80.40
9 INT241245 Negative_regulation of PKD2 2 0.42 2.35 0 79.84
10 INT271915 Negative_regulation of Pkd1 8 0.36 6.44 0 79.84
11 INT60724 Gene_expression of Psen2 30 0.72 27 5.79 78.80
12 INT159221 Negative_regulation of TBX1 4 0.41 4.22 0.43 75.00
13 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14 24.08
14 INT58765 Positive_regulation of Gene_expression of ANGPT2 11 0.38 8.2 0.81 24.08
15 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 23.12
16 INT58766 Gene_expression of ANGPT2 41 0.67 21.65 4.82 22.48
17 INT54886 Negative_regulation of ANGPT2 25 0.42 9.33 3.79 20.84
18 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
19 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
20 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 5.00
21 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9 5.00
22 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 5.00
23 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 5.00
24 INT17561 Localization of Car2 303 0.79 60.95 44.52 5.00
25 INT65698 Localization of CCL2 118 0.81 77.54 32.69 5.00
26 INT29743 Negative_regulation of App 91 0.59 65.56 31.26 5.00
27 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 5.00
28 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
29 INT17962 Regulation of Car2 124 0.41 33.98 22.71 5.00
30 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 5.00
31 INT23564 Negative_regulation of Car2 103 0.50 27.28 21.86 5.00
32 INT11625 Localization of App 98 0.78 55.46 20.86 5.00
33 INT16794 Binding of App 103 0.48 64.87 19.79 5.00
34 INT65502 Regulation of App 77 0.62 52.05 19.44 5.00
35 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92 5.00
36 INT110767 Localization of Mcpt1 43 0.68 24.3 16.74 5.00
37 INT18773 Localization of ALB 117 0.80 69.18 13.8 5.00
38 INT98789 Negative_regulation of Gene_expression of App 54 0.58 40.27 11.15 5.00
39 INT10879 Positive_regulation of Avp 39 0.65 14.01 8.76 5.00
40 INT111069 Regulation of Psen1 19 0.44 7.78 5.87 5.00
41 INT170516 Negative_regulation of Gene_expression of Car2 35 0.35 9.4 5.48 5.00
42 INT63957 Positive_regulation of Tnnt2 33 0.69 18.56 5.41 5.00
43 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19 5.00
44 INT74051 Negative_regulation of Localization of Car2 27 0.38 9.58 5.1 5.00
45 INT131692 Negative_regulation of Localization of App 9 0.53 4.69 4.82 5.00
46 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 5.00
47 INT76467 Regulation of Gene_expression of Car2 41 0.37 12.88 4.21 5.00
48 INT117205 Transcription of Esr1 23 0.65 9.4 4.14 5.00
49 INT146758 Gene_expression of LCN2 45 0.78 38.29 2.97 5.00
50 INT155889 Binding of Nps 22 0.42 9.79 2.6 5.00
51 INT37057 Gene_expression of Tlx2 12 0.76 7.98 2.38 5.00
52 INT55470 Regulation of Mtor 16 0.24 12.51 2.07 5.00
53 INT37485 Regulation of RAPGEF5 10 0.44 6.64 1.51 5.00
54 INT9784 Binding of B2M 9 0.47 6.18 1.44 5.00
55 INT47734 Positive_regulation of RAPGEF5 19 0.56 13.16 1.41 5.00
56 INT47434 Gene_expression of Tnnt2 14 0.60 10.4 1.37 5.00
57 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35 5.00
58 INT170507 Localization of Tmie 27 0.43 6.25 1.31 5.00
59 INT146759 Positive_regulation of LCN2 18 0.69 18.44 1.08 5.00
60 INT224722 Binding of Mcpt1 6 0.10 4.82 1.03 5.00
61 INT273283 Negative_regulation of Tmie 4 0.25 1.69 0.84 5.00
62 INT2108 Localization of Mif 5 0.77 2.7 0.73 5.00
63 INT63958 Regulation of Tnnt2 7 0.45 5.36 0.7 5.00
64 INT137850 Gene_expression of PKD2 9 0.65 6.68 0.63 5.00
65 INT164595 Binding of LCN2 8 0.37 6.03 0.6 5.00
66 INT241243 Gene_expression of Pkd2 30 0.77 9.05 0.53 5.00
67 INT166435 Negative_regulation of Atp2a2 8 0.43 0.4 0.44 5.00
68 INT11118 Gene_expression of RAPGEF5 13 0.65 9.35 0.43 5.00
69 INT241236 Negative_regulation of Pkd2 11 0.43 1.82 0.39 5.00
70 INT150826 Positive_regulation of Pkd1 9 0.37 3.65 0.35 5.00
71 INT236270 Binding of Hhex 2 0.07 1.55 0.29 5.00
72 INT185047 Gene_expression of Pln 8 0.52 1.65 0.29 5.00
73 INT241240 Gene_expression of Pkd1 18 0.54 12.2 0.27 5.00
74 INT134778 Phosphorylation of Pln 6 0.70 3.51 0.22 5.00
75 INT87089 Gene_expression of Ssm1 5 0.04 2.81 0.21 5.00
76 INT120202 Gene_expression of Ern1 2 0.14 1.78 0.21 5.00
77 INT273279 Negative_regulation of Localization of Tmie 2 0.07 1.72 0.2 5.00
78 INT132459 Binding of FABP3 4 0.35 2.19 0.2 5.00
79 INT208476 Binding of Pkd1 13 0.39 7.23 0.17 5.00
80 INT81942 Regulation of Regulation of Car2 5 0.29 0.43 0.16 5.00
81 INT166433 Gene_expression of Atp2a2 7 0.68 2.82 0.15 5.00
82 INT354535 Regulation of Negative_regulation of Pkd2 1 0.15 1.03 0.14 5.00
83 INT311275 Regulation of Gene_expression of Tnnt2 2 0.34 1.33 0.1 5.00
84 INT121284 Positive_regulation of Gene_expression of Tnnt2 2 0.46 0.89 0.1 5.00
85 INT273285 Negative_regulation of Localization of Psen1 1 0.36 0.99 0.09 5.00
86 INT121285 Regulation of Positive_regulation of Tnnt2 2 0.45 0.84 0.09 5.00
87 INT354534 Binding of Havcr1 1 0.03 0.81 0.08 5.00
88 INT243806 Negative_regulation of Tfrc 2 0.12 0.43 0.08 5.00
89 INT354537 Positive_regulation of Positive_regulation of Pkd1 1 0.29 1.7 0.06 5.00
90 INT261879 Binding of PKD2 3 0.13 2.59 0.05 5.00
91 INT354536 Positive_regulation of Hhex 1 0.08 0.62 0.04 5.00
92 INT286543 Localization of Pkd1 5 0.52 3.74 0.04 5.00
93 INT156365 Gene_expression of Hhex 4 0.67 1.63 0.03 5.00
94 INT273282 Negative_regulation of Gene_expression of Tlx2 1 0.19 0.52 0 5.00
95 INT354543 Regulation of Gene_expression of RAPGEF5 1 0.03 0.82 0 5.00
96 INT273284 Negative_regulation of Gene_expression of Pln 3 0.29 0.72 0 5.00
97 INT263569 Phosphorylation of Hspa5 2 0.42 1.63 0 5.00
98 INT273277 Phosphorylation of Calr 2 0.56 0.82 0 5.00
99 INT273281 Regulation of Negative_regulation of Atp2a2 1 0.11 0.23 0 5.00
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