D:Duchenne Muscular Dystrophy

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Disease Term
Synonyms BECKER MUSCULAR DYSTROPHY, Childhood Muscular Dystrophy Pseudohypertrophic, CHILDHOOD PSEUDOHYPERTROPHIC MUSCULAR DYSTROPHY, DUCHENNE TYPE PROGRESSIVE MUSCULAR DYSTROPHY, Dystrophies Pseudohypertrophic Muscular, Dystrophy Becker Muscular, Dystrophy Duchenne Muscular, Dystrophy Pseudohypertrophic Muscular, Muscular Dystrophies Pseudohypertrophic, MUSCULAR DYSTROPHY BECKER, Muscular Dystrophy Childhood Pseudohypertrophic
Documents 30
Hot Single Events 18
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Duchenne Muscular Dystrophy. They are ordered first by their relevance to Duchenne Muscular Dystrophy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT283199 Binding of DMD and PTPRC 1 0.01 0.82 0 46.08
2 INT283201 Gm4658 Regulation of Gnas 1 0.00 0.56 0 16.04
3 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 5.00
4 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16 5.00
5 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13 5.00
6 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12 5.00
7 INT356379 DMD Positive_regulation of Negative_regulation of Utrn 1 0.54 0.84 0.07 5.00
8 INT339583 Binding of ABCA1 and RPE 1 0.03 1.38 0.05 5.00
9 INT339587 Positive_regulation of Binding of ABCA1 and RPE 1 0.04 1.38 0.05 5.00
10 INT283202 Gm4658 Positive_regulation of Gene_expression of DMD 1 0.01 0.33 0.03 5.00
11 INT339582 AMD1 Regulation of C1QTNF5 1 0.07 2 0 5.00
12 INT339581 Binding of TIMP1 and TIMP3 1 0.30 0.54 0 5.00
13 INT339580 TIMP3 Positive_regulation of ABCA1 1 0.16 0.73 0 5.00
14 INT356377 Dmd Positive_regulation of Negative_regulation of Mib2 1 0.03 0.51 0 5.00
15 INT339585 Binding of AMD1 and MDM1 1 0.06 2.02 0 5.00
16 INT339586 TIMP3 Positive_regulation of RPE 1 0.16 0.72 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Duchenne Muscular Dystrophy. They are ordered first by their pain relevance and then by number of times they were reported in Duchenne Muscular Dystrophy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT227759 Gene_expression of Best1 26 0.42 20.36 1.73 100.00
2 INT356374 Gene_expression of Mib2 1 0.07 2.53 0.03 99.84
3 INT267844 Positive_regulation of Gene_expression of Ace 10 0.57 15.35 0.35 99.80
4 INT60040 Negative_regulation of Negative_regulation of Ace 6 0.43 3.64 0.38 99.34
5 INT307794 Negative_regulation of Gene_expression of Ace 7 0.48 5.95 0.2 99.34
6 INT51869 Negative_regulation of Dmd 24 0.52 10.4 2.18 99.08
7 INT27670 Negative_regulation of Ace 122 0.57 79.21 18.08 98.84
8 INT16165 Regulation of DMD 114 0.60 35.13 3.64 98.80
9 INT74695 Gene_expression of Ace 41 0.73 53.33 2.33 98.28
10 INT5489 Localization of CA2 172 0.80 39.46 33.56 96.52
11 INT205401 Gene_expression of Chkb 32 0.51 13.99 0.77 93.12
12 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45 91.00
13 INT216104 Positive_regulation of Gene_expression of Dmd 23 0.46 4.52 0.68 88.64
14 INT95696 Gene_expression of Dmd 130 0.68 26.02 5.34 88.00
15 INT62155 Positive_regulation of Gene_expression of DMD 17 0.67 6.17 0.82 87.36
16 INT62156 Transcription of DMD 1 0.69 1.6 0 85.76
17 INT260795 Localization of Chkb 12 0.33 11.12 1.53 84.80
18 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 81.84
19 INT207777 Binding of Ap3d1 1 0.07 14.51 1.91 76.68
20 INT207778 Positive_regulation of Binding of Ap3d1 1 0.06 1.26 0.52 76.68
21 INT139009 Positive_regulation of Localization of Cir1 10 0.44 2.98 1.55 75.00
22 INT119803 Localization of Cir1 12 0.70 3.39 2 75.00
23 INT9953 Positive_regulation of Gnas 10 0.34 3.21 1.51 74.04
24 INT100172 Positive_regulation of Utrn 6 0.67 5.35 0.51 72.76
25 INT356371 Localization of Agtr2 1 0.04 0.74 0.11 72.08
26 INT207779 Localization of Ap3d1 1 0.11 3.16 0.14 71.28
27 INT69768 Negative_regulation of Pscs 7 0.51 4.76 2.82 69.60
28 INT109925 Gene_expression of RPE 11 0.65 12.46 0.68 63.20
29 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 57.84
30 INT13397 Localization of DMD 21 0.78 7.96 1.08 57.04
31 INT100171 Gene_expression of Utrn 17 0.75 3.93 0.98 53.84
32 INT356373 Transcription of Utrn 1 0.67 0.42 0 45.20
33 INT245157 Negative_regulation of Gene_expression of DMD 8 0.57 4.79 0.09 41.32
34 INT171998 Binding of DMD 58 0.47 38.13 3.35 41.04
35 INT356372 Negative_regulation of Utrn 1 0.57 1.23 0.07 40.80
36 INT356376 Regulation of Negative_regulation of Utrn 1 0.44 0.41 0 40.80
37 INT60552 Localization of TNNI3 56 0.79 20.05 1.44 36.88
38 INT356378 Protein_catabolism of TNNI1 1 0.96 0.31 0 36.08
39 INT11258 Gene_expression of Gnas 58 0.58 21.6 6.33 33.24
40 INT129534 Gene_expression of Nppb 19 0.58 23.68 1.6 31.20
41 INT356369 Negative_regulation of Gene_expression of Mib2 1 0.05 0.81 0 12.56
42 INT216108 Negative_regulation of Gene_expression of Dmd 12 0.45 1.32 0.46 11.92
43 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76 5.00
44 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
45 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 5.00
46 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87 5.00
47 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32 5.00
48 INT64110 Positive_regulation of Gene_expression of Nos1 68 0.70 58.11 51.64 5.00
49 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42 5.00
50 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 5.00
51 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 5.00
52 INT111531 Negative_regulation of Phosphorylation of Mapk14 37 0.50 20 17.68 5.00
53 INT69769 Positive_regulation of Pscs 61 0.56 39.32 15.93 5.00
54 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36 5.00
55 INT55687 Localization of TIMP1 47 0.74 30.24 12.31 5.00
56 INT36453 Binding of ABCA1 48 0.45 19.9 10.84 5.00
57 INT111992 Gene_expression of Pscs 40 0.76 27.47 10.74 5.00
58 INT62919 Regulation of Gnas 22 0.43 5.61 9.55 5.00
59 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27 5.00
60 INT65265 Positive_regulation of Gene_expression of Col7a1 48 0.69 23.81 6.16 5.00
61 INT64111 Negative_regulation of Gene_expression of Nos1 22 0.57 8.96 6.02 5.00
62 INT109124 Positive_regulation of TIMP3 8 0.61 5.57 5.72 5.00
63 INT80038 Positive_regulation of Gene_expression of MYC 24 0.67 13.93 5.17 5.00
64 INT59555 Binding of RYR1 39 0.42 8.65 4.92 5.00
65 INT21855 Gene_expression of Ap3d1 4 0.32 12.21 4.66 5.00
66 INT154527 Gene_expression of POU5F1 180 0.78 34.01 4.34 5.00
67 INT43931 Binding of CFH 49 0.48 31.85 3.96 5.00
68 INT18670 Negative_regulation of ABCA1 16 0.54 5.8 3.39 5.00
69 INT15648 Positive_regulation of RYR1 30 0.67 12.03 3.26 5.00
70 INT9549 Regulation of CHKB 25 0.47 13.61 3.2 5.00
71 INT26273 Negative_regulation of RYR1 18 0.43 7.64 3.11 5.00
72 INT21853 Regulation of Ap3d1 3 0.10 1.4 2.95 5.00
73 INT24712 Positive_regulation of Ap3d1 18 0.54 8.58 2.71 5.00
74 INT50080 Binding of APOE 38 0.45 29.61 2.67 5.00
75 INT6508 Gene_expression of RYR1 34 0.77 11.11 2.04 5.00
76 INT107987 Gene_expression of MRC1 27 0.75 36.94 1.99 5.00
77 INT11713 Localization of RYR1 22 0.76 10.42 1.64 5.00
78 INT21852 Regulation of Gene_expression of Ap3d1 2 0.18 1.34 1.54 5.00
79 INT115659 Gene_expression of ABCB6 29 0.75 13.59 1.43 5.00
80 INT111996 Positive_regulation of Gene_expression of Pscs 8 0.34 4.37 1.42 5.00
81 INT22871 Gene_expression of ELN 30 0.68 14.86 1.33 5.00
82 INT55305 Regulation of RYR1 14 0.45 5.27 1.33 5.00
83 INT282590 Positive_regulation of Gene_expression of POU5F1 40 0.70 8.42 1.32 5.00
84 INT260525 Gene_expression of AMD1 25 0.66 24.58 1.32 5.00
85 INT74254 Binding of PTPRC 16 0.36 8.37 1.27 5.00
86 INT11367 Localization of MB 9 0.78 9.34 1.24 5.00
87 INT143759 Gene_expression of SOX2 46 0.55 11.12 1.24 5.00
88 INT216103 Positive_regulation of Dmd 15 0.46 5.92 1.21 5.00
89 INT21546 Regulation of ABCA1 16 0.40 4.21 1.04 5.00
90 INT116314 Gene_expression of Myod1 38 0.70 16.6 0.89 5.00
91 INT134753 Gene_expression of TIMP3 19 0.68 15.24 0.88 5.00
92 INT45722 Negative_regulation of CFHR1 6 0.56 1.43 0.78 5.00
93 INT257447 Binding of TBCE 4 0.08 4.68 0.66 5.00
94 INT63064 Gene_expression of PRM1 7 0.50 2.66 0.65 5.00
95 INT207780 Positive_regulation of NMS 2 0.28 3.2 0.61 5.00
96 INT197512 Gene_expression of ABCA4 19 0.75 7.08 0.57 5.00
97 INT202940 Binding of AMD1 13 0.41 16.43 0.56 5.00
98 INT109904 Localization of RPE 5 0.73 4.9 0.56 5.00
99 INT109903 Positive_regulation of Gene_expression of RPE 3 0.49 0.59 0.46 5.00
100 INT161027 Negative_regulation of RPE 7 0.37 4.34 0.38 5.00
101 INT165400 Positive_regulation of TST 13 0.68 4.25 0.35 5.00
102 INT280603 Transcription of Myod1 4 0.67 1.22 0.24 5.00
103 INT339593 Gene_expression of FBLN1 2 0.14 3.01 0.24 5.00
104 INT272484 Negative_regulation of Myod1 8 0.39 6.77 0.2 5.00
105 INT49908 Regulation of Gene_expression of RYR1 3 0.45 0.32 0.19 5.00
106 INT63067 Localization of MYC 13 0.78 6.93 0.19 5.00
107 INT189564 Binding of TIMP3 4 0.31 2.45 0.17 5.00
108 INT13398 Regulation of Gene_expression of DMD 5 0.44 0.6 0.17 5.00
109 INT283194 Gene_expression of Vamp8 1 0.13 0.59 0.16 5.00
110 INT316913 Positive_regulation of Positive_regulation of Utrn 2 0.49 1.88 0.16 5.00
111 INT109930 Positive_regulation of RPE 4 0.49 5.88 0.15 5.00
112 INT272949 Positive_regulation of Myod1 6 0.36 5.31 0.14 5.00
113 INT356370 Phosphorylation of Mapkbp1 1 0.07 1.52 0.12 5.00
114 INT356375 Positive_regulation of Phosphorylation of Mapkbp1 1 0.06 1.53 0.12 5.00
115 INT249052 Protein_catabolism of SMN1 1 0.02 1.98 0.1 5.00
116 INT268715 Binding of RPE 3 0.09 2.36 0.09 5.00
117 INT283198 Regulation of Gene_expression of Vamp8 1 0.09 0.27 0.09 5.00
118 INT282593 Gene_expression of KLF4 8 0.61 1.09 0.09 5.00
119 INT282591 Positive_regulation of Gene_expression of SOX2 4 0.36 1.07 0.08 5.00
120 INT144322 Regulation of RPE 1 0.24 1.9 0.08 5.00
121 INT186637 Regulation of ABCA4 3 0.37 2.02 0.07 5.00
122 INT233399 Binding of ABCA4 9 0.46 9.49 0.07 5.00
123 INT282606 Positive_regulation of Gene_expression of KLF4 2 0.54 0.8 0.04 5.00
124 INT207781 Gene_expression of CACNA1S 3 0.63 0.9 0.03 5.00
125 INT207782 Binding of CACNA1S 1 0.30 0.53 0.03 5.00
126 INT339590 Negative_regulation of Gene_expression of FBLN1 1 0.10 2.61 0 5.00
127 INT339598 Gene_expression of ARMS2 1 0.65 1.03 0 5.00
128 INT274183 Negative_regulation of Gene_expression of ELN 3 0.30 3.29 0 5.00
129 INT339592 Regulation of ARMS2 2 0.26 2.27 0 5.00
130 INT231153 Positive_regulation of Positive_regulation of Dmd 2 0.29 1.43 0 5.00
131 INT339591 Positive_regulation of Gene_expression of FBLN1 1 0.08 1.31 0 5.00
132 INT339599 Negative_regulation of CFHR3 1 0.33 1.05 0 5.00
133 INT356367 Negative_regulation of Mib2 1 0.04 0.5 0 5.00
134 INT283196 Regulation of Vamp8 1 0.09 0.05 0 5.00
135 INT213395 Positive_regulation of Gene_expression of ABCA4 2 0.41 1.22 0 5.00
136 INT339595 Negative_regulation of RPE65 1 0.34 0.64 0 5.00
137 INT339596 Localization of KLF4 1 0.26 0 0 5.00
138 INT283195 Gene_expression of Gm4658 1 0.01 0.18 0 5.00
139 INT282585 Localization of POU5F1 3 0.67 0.08 0 5.00
140 INT189570 Positive_regulation of Gene_expression of TIMP3 3 0.44 1.57 0 5.00
141 INT339594 Localization of SOX2 2 0.69 0.7 0 5.00
142 INT339597 Gene_expression of RPE65 1 0.54 0.29 0 5.00
143 INT190446 Gene_expression of NR2E3 11 0.10 0.89 0 5.00
144 INT283197 Positive_regulation of Gene_expression of Vamp8 1 0.10 0 0 5.00
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