D:Dysgeusia

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Disease Term
Synonyms ALTERED TASTE, Distorted Taste, Dysgeusias, PARAGEUSIA, Parageusias, TASTE ALTERED, Taste Distorted
Documents 112
Hot Single Events 13
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Dysgeusia. They are ordered first by their relevance to Dysgeusia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03 57.76
2 INT295552 Binding of Ghrl and Ghsr 7 0.40 1.64 0.88 5.00
3 INT295546 Ghrl Positive_regulation of Ghsr 3 0.39 0.09 0.77 5.00
4 INT258521 EGFR Positive_regulation of MMP2 1 0.39 0.91 0.24 5.00
5 INT258565 EGFR Positive_regulation of Meta 1 0.39 0.89 0.23 5.00
6 INT219027 Prl Positive_regulation of Localization of TRPV1 1 0.04 0.65 0.21 5.00
7 INT219028 Prl Positive_regulation of Regulation of TRPV1 1 0.03 0.65 0.21 5.00
8 INT295540 Binding of Gh and Ghrl 2 0.10 0.13 0.12 5.00
9 INT258527 Binding of BRAF and RET 1 0.21 1.49 0.11 5.00
10 INT277692 Binding of Atp9a and Tnfrsf10b 1 0.00 1.47 0.1 5.00
11 INT258522 Binding of DDR1 and RET 1 0.03 1.05 0.1 5.00
12 INT249117 Binding of Abl1 and Bcr 4 0.36 2.22 0.09 5.00
13 INT268679 Binding of HDAC1 and NCOR2 3 0.17 2.8 0.07 5.00
14 INT251892 Binding of Plau and Naf1 1 0.07 0.06 0.04 5.00
15 INT277693 Stat6 Positive_regulation of Positive_regulation of Casp3 1 0.01 1.01 0 5.00
16 INT277691 Cdkn1a Negative_regulation of Positive_regulation of Casp3 1 0.00 1.01 0 5.00
17 INT258524 IPMK Negative_regulation of KDR 2 0.00 1.98 0 5.00
18 INT284919 XRCC6 Negative_regulation of BAX 1 0.01 0.64 0 5.00
19 INT211883 Binding of RET and CDCP1 1 0.00 2.12 0 5.00
20 INT284920 Binding of HDAC1 and NCOR1 1 0.03 0.13 0 5.00
21 INT297614 ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.56 0 5.00
22 INT284918 RUNX1T1 Regulation of DNMT1 1 0.21 1.09 0 5.00
23 INT284917 RUNX1T1 Regulation of HDAC9 1 0.19 1.09 0 5.00
24 INT284914 Binding of HDAC1 and NCK1 1 0.00 0.13 0 5.00
25 INT297613 Negative_regulation of ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.66 0 5.00
26 INT258523 Positive_regulation of RAF1 Positive_regulation of Phosphorylation of GSK 1 0.19 0.64 0 5.00
27 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0 5.00
28 INT251893 Serpine1 Negative_regulation of Plau 1 0.39 0.6 0 5.00
29 INT297615 Binding of TSC1 and HDAC9 1 0.01 0.4 0 5.00
30 INT251891 Serpine1 Negative_regulation of Plg 1 0.12 3.13 0 5.00
31 INT258526 IPMK Negative_regulation of BRAF 1 0.01 1.11 0 5.00
32 INT352482 Binding of PCA and Uncx 1 0.00 0.06 0 5.00
33 INT284915 Binding of CDKN2B and HIST2H3C 1 0.05 0.43 0 5.00
34 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0 5.00
35 INT258525 IPMK Negative_regulation of DDR1 2 0.00 1.97 0 5.00
36 INT284995 Binding of HDAC1 and Sin3a 1 0.00 0.13 0 5.00
37 INT277694 Cdkn1a Positive_regulation of Positive_regulation of Casp3 1 0.00 1.01 0 5.00
38 INT211882 Binding of KIT and CDCP1 1 0.00 2.1 0 5.00
39 INT331405 Binding of Gh and Ghsr 1 0.08 0.13 0 5.00
40 INT258564 Binding of NOTCH1 and Crlf2 1 0.27 0.67 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Dysgeusia. They are ordered first by their pain relevance and then by number of times they were reported in Dysgeusia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT166105 Binding of ptd 1 0.32 0.95 0.12 100.00
2 INT166106 Localization of ptd 1 0.60 0.94 0.14 100.00
3 INT197446 Localization of Psmd1 10 0.56 3.78 2.79 96.28
4 INT83236 Localization of PGR 14 0.73 8.26 2.23 91.40
5 INT221097 Negative_regulation of Atp8a1 15 0.57 10.52 2.65 91.36
6 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 90.56
7 INT21487 Negative_regulation of HCC 18 0.49 29.81 1.88 88.96
8 INT220783 Gene_expression of Tert 39 0.77 12.55 1.49 86.48
9 INT149091 Gene_expression of Ghsr 42 0.76 5.11 4.6 85.60
10 INT284973 Negative_regulation of Negative_regulation of HDAC1 1 0.20 1.59 0.04 84.20
11 INT177842 Negative_regulation of HDAC1 6 0.31 4.65 0.49 83.36
12 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19 83.12
13 INT284958 Negative_regulation of HDAC6 1 0.25 1.56 0.04 81.56
14 INT18088 Binding of Tspo 26 0.48 9.12 10.2 79.12
15 INT284992 Negative_regulation of HDAC8 1 0.21 2.36 0.04 78.72
16 INT42994 Binding of BDNF-AS 21 0.35 14.17 4 76.84
17 INT97891 Gene_expression of Ghrl 108 0.77 24.85 9.7 70.52
18 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 64.20
19 INT149838 Binding of TSHB 5 0.14 3.27 1.1 56.08
20 INT144390 Positive_regulation of Negative_regulation of CYP2C9 4 0.49 2.03 0.72 54.96
21 INT277669 Positive_regulation of Negative_regulation of Cyp3a11 1 0.09 1.46 0.03 54.96
22 INT59929 Negative_regulation of CYP2C9 60 0.59 16.33 15.39 54.40
23 INT76024 Negative_regulation of Cyp3a11 7 0.53 2.96 3.16 54.40
24 INT331401 Regulation of Ghsr 1 0.38 0 0 48.56
25 INT331403 Gene_expression of Mboat4 1 0.75 0.19 0.1 48.16
26 INT109396 Negative_regulation of RET 12 0.42 14.92 1.06 46.12
27 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 44.48
28 INT21943 Positive_regulation of Positive_regulation of AGT 6 0.46 3.29 0.75 44.48
29 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 43.52
30 INT17399 Positive_regulation of Positive_regulation of REN 13 0.69 7.05 1.9 43.52
31 INT103327 Gene_expression of F8 45 0.71 32.5 2.12 41.32
32 INT52021 Regulation of IGHG3 34 0.39 22.43 3.3 39.04
33 INT275245 Positive_regulation of HIST2H2BE 2 0.15 1.94 0 38.00
34 INT297621 Positive_regulation of RLN3 1 0.05 2.79 0 38.00
35 INT1721 Negative_regulation of HP 148 0.42 86.82 16.89 32.40
36 INT165456 Positive_regulation of NAF1 3 0.42 0.77 0.56 30.80
37 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 29.84
38 INT185916 Gene_expression of NAF1 16 0.65 4.27 0.53 28.64
39 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 27.60
40 INT1761 Positive_regulation of PTGER2 135 0.49 90.17 26.26 20.28
41 INT115464 Gene_expression of Plau 41 0.72 30.21 2.79 19.72
42 INT115462 Positive_regulation of Gene_expression of Plau 14 0.65 7.35 0.53 19.72
43 INT125772 Positive_regulation of Negative_regulation of Serpine1 1 0.42 0.4 0.22 18.32
44 INT251887 Positive_regulation of Negative_regulation of Ptger2 2 0.28 1.07 0 18.32
45 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 17.92
46 INT15941 Negative_regulation of Serpine1 42 0.58 21.07 4.95 17.68
47 INT49509 Negative_regulation of Ptger2 53 0.42 24.87 11.66 17.28
48 INT49506 Regulation of Ptger2 29 0.44 17.38 6.75 14.12
49 INT57691 Regulation of Gene_expression of Ptger2 23 0.40 17.08 4.61 14.12
50 INT16263 Regulation of Serpine1 13 0.45 5.24 3.6 14.12
51 INT200606 Regulation of Gene_expression of Serpine1 4 0.38 2.07 0.35 14.12
52 INT251885 Regulation of Gene_expression of Plau 5 0.42 1.83 0.21 14.12
53 INT171219 Regulation of Plau 9 0.42 1.04 0.11 14.12
54 INT251889 Regulation of Naf1 1 0.07 0 0.03 14.12
55 INT20102 Gene_expression of Serpine1 102 0.78 65.99 12.61 13.52
56 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68 13.12
57 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 12.00
58 INT75266 Gene_expression of Psmd4 3 0.05 1.18 0.38 11.00
59 INT331397 Gene_expression of Psmd5 1 0.36 0 0.07 11.00
60 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 9.72
61 INT124852 Positive_regulation of Gene_expression of Tpt1 10 0.50 3.95 0.1 5.44
62 INT277667 Positive_regulation of Gene_expression of Ccne2 1 0.01 0.52 0 5.44
63 INT124850 Gene_expression of Tpt1 42 0.77 14.51 0.79 5.08
64 INT170847 Gene_expression of Ccne2 6 0.58 2.98 0.21 5.08
65 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 5.00
66 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
67 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 5.00
68 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
69 INT1893 Localization of Gh 1041 0.79 340.23 256.58 5.00
70 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
71 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 5.00
72 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
73 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
74 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
75 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 5.00
76 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
77 INT3214 Localization of Ins1 527 0.80 196.9 79.26 5.00
78 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46 5.00
79 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
80 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
81 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6 5.00
82 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
83 INT11807 Gene_expression of Il2 266 0.78 112 64.97 5.00
84 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35 5.00
85 INT31186 Negative_regulation of Insrr 81 0.37 24.91 55.94 5.00
86 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 5.00
87 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 5.00
88 INT654 Localization of REN 250 0.81 75.12 47.86 5.00
89 INT9383 Localization of TRPV1 98 0.81 33.23 46.24 5.00
90 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
91 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
92 INT6417 Negative_regulation of ABAT 49 0.51 19.6 36.81 5.00
93 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15 5.00
94 INT3913 Positive_regulation of ABAT 47 0.69 22.73 33.4 5.00
95 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 5.00
96 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08 5.00
97 INT90792 Localization of Il10 144 0.80 87.88 30.03 5.00
98 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 5.00
99 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47 5.00
100 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 5.00
101 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
102 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 5.00
103 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 5.00
104 INT2140 Regulation of REN 104 0.62 28.24 24.49 5.00
105 INT48312 Gene_expression of NTRK1 72 0.78 38.21 22.24 5.00
106 INT20379 Localization of Il4 85 0.73 51.22 20.55 5.00
107 INT1764 Negative_regulation of Gene_expression of PTGER2 81 0.34 34.74 19.45 5.00
108 INT19509 Localization of Ifng 55 0.78 28.25 18.67 5.00
109 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 5.00
110 INT35086 Positive_regulation of Gene_expression of Ifng 40 0.69 22.55 18.35 5.00
111 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 5.00
112 INT61519 Gene_expression of Mpo 112 0.78 89.29 18.22 5.00
113 INT18621 Binding of ABAT 28 0.36 9.88 18.04 5.00
114 INT21532 Negative_regulation of Gene_expression of Il2 47 0.59 20.43 16.96 5.00
115 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 5.00
116 INT653 Negative_regulation of Localization of REN 67 0.59 20.33 16.7 5.00
117 INT10187 Gene_expression of Il2ra 91 0.78 52.67 16.66 5.00
118 INT6480 Positive_regulation of IL1RN 59 0.69 33.7 16.66 5.00
119 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 5.00
120 INT8742 Regulation of Localization of Ins1 65 0.61 14.98 16.43 5.00
121 INT1981 Negative_regulation of NARFL 219 0.47 223.48 16.41 5.00
122 INT3400 Positive_regulation of pr 57 0.68 36.9 16.24 5.00
123 INT108780 Positive_regulation of Gene_expression of Ptger2 94 0.49 59.71 16.22 5.00
124 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 5.00
125 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89 5.00
126 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8 5.00
127 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74 5.00
128 INT16321 Gene_expression of Cd3e 111 0.72 49.9 14.21 5.00
129 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 5.00
130 INT15684 Positive_regulation of Serpine1 65 0.70 43.51 13.67 5.00
131 INT655 Positive_regulation of Localization of REN 86 0.70 32.41 13.56 5.00
132 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
133 INT7532 Negative_regulation of Gene_expression of Ifng 33 0.59 18.56 13.14 5.00
134 INT20381 Localization of Il2 71 0.77 34.23 13.03 5.00
135 INT3962 Regulation of AGT 50 0.62 20.96 13.01 5.00
136 INT39564 Negative_regulation of Gene_expression of Ptger2 50 0.42 30.9 12.97 5.00
137 INT178338 Gene_expression of Tbx15 50 0.65 38.65 12.19 5.00
138 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18 5.00
139 INT184844 Gene_expression of Snap25 130 0.78 14.32 12.13 5.00
140 INT8548 Gene_expression of HP 86 0.77 47.62 11.94 5.00
141 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 5.00
142 INT661 Gene_expression of REN 100 0.78 48.21 11.36 5.00
143 INT1762 Negative_regulation of PTGER2 64 0.43 28.21 11.27 5.00
144 INT8065 Binding of AGT 54 0.48 20.54 10.85 5.00
145 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84 5.00
146 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69 5.00
147 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 5.00
148 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 5.00
149 INT114874 Gene_expression of Stat3 78 0.76 53.99 9.49 5.00
150 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 5.00
151 INT224964 Localization of Ghrl 30 0.59 7.71 8.77 5.00
152 INT66041 Positive_regulation of NTRK1 24 0.70 16.12 8.42 5.00
153 INT25387 Binding of Ptger2 42 0.47 16 7.98 5.00
154 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 5.00
155 INT18909 Positive_regulation of Cd8a 92 0.60 56.55 7.35 5.00
156 INT102572 Gene_expression of Ccnd1 79 0.69 56.37 7.34 5.00
157 INT6596 Positive_regulation of HLA-DRB1 33 0.61 27.01 7.26 5.00
158 INT79062 Gene_expression of B4GALNT1 42 0.14 18.89 6.98 5.00
159 INT35486 Regulation of PTGER2 39 0.36 19.03 6.75 5.00
160 INT39516 Gene_expression of Alb 81 0.75 30.08 6.59 5.00
161 INT192225 Gene_expression of HDAC9 35 0.58 32.82 6.36 5.00
162 INT11154 Binding of EGFR 149 0.48 96.23 6.29 5.00
163 INT11814 Positive_regulation of Alb 43 0.63 31.71 6.28 5.00
164 INT48313 Binding of NTRK1 19 0.47 14.44 6.12 5.00
165 INT63177 Regulation of HP 71 0.44 39.48 5.86 5.00
166 INT17892 Gene_expression of Myc 57 0.75 36.37 5.82 5.00
167 INT179810 Protein_catabolism of Ecm1 30 0.11 18.28 5.75 5.00
168 INT62270 Positive_regulation of Gene_expression of Cdkn1a 30 0.47 18.73 5.69 5.00
169 INT32458 Gene_expression of VWF 57 0.78 28.97 5.56 5.00
170 INT22839 Gene_expression of F2 31 0.74 15.53 5.56 5.00
171 INT5490 Binding of CA2 52 0.36 9.73 5.53 5.00
172 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42 5.00
173 INT201130 Localization of AES 31 0.63 25.45 5.12 5.00
174 INT141275 Negative_regulation of Gene_expression of Hand1 18 0.34 15.83 5.05 5.00
175 INT28145 Binding of PAPPA 26 0.48 7.4 4.96 5.00
176 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 5.00
177 INT18011 Positive_regulation of HP 60 0.50 31.88 4.75 5.00
178 INT55114 Gene_expression of CRS 42 0.58 26.86 4.69 5.00
179 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 5.00
180 INT272273 Gene_expression of NARFL 89 0.54 121.19 4.47 5.00
181 INT8743 Positive_regulation of Gcg 19 0.65 10.63 4.43 5.00
182 INT141000 Negative_regulation of GSK 24 0.57 9.46 4.4 5.00
183 INT26477 Regulation of ACE 26 0.45 16.31 4.33 5.00
184 INT22973 Gene_expression of Col3a1 22 0.42 15.85 4.32 5.00
185 INT5219 Negative_regulation of DBP 43 0.57 23.35 4.26 5.00
186 INT17324 Negative_regulation of Plg 26 0.38 13.5 4.05 5.00
187 INT40036 Binding of DLL1 10 0.36 2.88 3.95 5.00
188 INT170455 Gene_expression of Atp8a1 66 0.75 24.63 3.94 5.00
189 INT93110 Regulation of CDCP1 16 0.03 7.98 3.83 5.00
190 INT103350 Gene_expression of DNMT1 15 0.67 9.77 3.83 5.00
191 INT123908 Positive_regulation of HLA-DQB1 12 0.21 10.5 3.71 5.00
192 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7 5.00
193 INT12598 Binding of DBP 20 0.48 13.11 3.62 5.00
194 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61 5.00
195 INT226114 Binding of Ghrl 18 0.36 4.34 3.54 5.00
196 INT193281 Binding of CAP1 7 0.07 4.57 3.53 5.00
197 INT12923 Negative_regulation of Atp9a 17 0.35 7.87 3.52 5.00
198 INT89966 Negative_regulation of Fas 26 0.58 24.83 3.5 5.00
199 INT8096 Positive_regulation of Gene_expression of EGF 21 0.69 13.43 3.47 5.00
200 INT124579 Localization of BAX 35 0.78 30.31 3.43 5.00
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