D:Dyslexia

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Disease Term
Synonyms ALEXIA, Alexias, Blindness Word, Blindnesses Word, Developmental Dyslexia, Developmental Dyslexias, DEVELOPMENTAL READING DISABILITIES, Developmental Reading Disability, Developmental Reading Disorder, Developmental Reading Disorders, Disabilities Developmental Reading
Documents 75
Hot Single Events 7
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Dyslexia. They are ordered first by their relevance to Dyslexia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT335742 Binding of PDB1 and Dpyd 1 0.02 1.75 0.09 61.12
2 INT335743 Binding of PDB1 and Salpa1 1 0.01 1.66 0.09 56.40
3 INT189859 Binding of SLC6A3 and ADHD1 2 0.32 0.68 0.48 5.00
4 INT310674 Positive_regulation of Binding of ARSB and ELF3 1 0.07 2.46 0.05 5.00
5 INT310675 Binding of ARSB and ELF3 1 0.06 2.4 0.05 5.00
6 INT324347 Binding of UMOD and Scr 1 0.20 2.23 0 5.00
7 INT324342 UMOD Positive_regulation of Scr 1 0.17 1.29 0 5.00
8 INT335736 Binding of Map1lc3a and Map1lc3b 1 0.19 0.36 0 5.00
9 INT324312 Binding of GATM and UMOD 1 0.02 1.62 0 5.00
10 INT324306 Binding of GATM and STC1 1 0.02 1.61 0 5.00
11 INT299946 Binding of Tlr4 and Synj2bp 1 0.00 0.28 0 5.00
12 INT324346 Regulation of UMOD Positive_regulation of Scr 1 0.10 1.31 0 5.00
13 INT324343 SLC12A1 Regulation of Scr 1 0.00 0.25 0 5.00
14 INT324305 Binding of CST3 and UMOD 1 0.05 3.22 0 5.00
15 INT324313 Binding of STC1 and UMOD 1 0.29 3.22 0 5.00
16 INT324311 Binding of UMOD and SHROOM3 1 0.29 1.62 0 5.00
17 INT324310 Binding of STC1 and SHROOM3 1 0.24 1.61 0 5.00
18 INT324344 Positive_regulation of UMOD Regulation of Scr 1 0.24 0.29 0 5.00
19 INT324340 Binding of SLC12A1 and Scr 1 0.00 1.42 0 5.00
20 INT324309 Binding of CST3 and GATM 1 0.00 1.6 0 5.00
21 INT324345 Binding of STC1 and Scr 1 0.10 0.22 0 5.00
22 INT324341 UMOD Regulation of Scr 1 0.21 0.29 0 5.00
23 INT324308 Binding of CST3 and SHROOM3 1 0.04 1.6 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Dyslexia. They are ordered first by their pain relevance and then by number of times they were reported in Dyslexia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT7581 Binding of ADHD1 132 0.46 135.1 19.73 95.72
2 INT310677 Localization of ARSB 1 0.71 5.72 0.14 93.08
3 INT95048 Negative_regulation of ADHD1 61 0.51 56.01 5.62 92.04
4 INT335738 Positive_regulation of VCP 1 0.06 1.88 0.06 91.48
5 INT272256 Protein_catabolism of Psd 3 0.49 2.66 0.19 84.84
6 INT335735 Binding of Atp13a3 2 0.03 1.17 0.24 83.80
7 INT130603 Binding of Timp1 9 0.35 8.52 3.04 80.84
8 INT310680 Gene_expression of ARSB 1 0.64 6.28 0.12 79.36
9 INT97216 Positive_regulation of Psd 13 0.45 7.04 1.25 75.64
10 INT184852 Positive_regulation of Gene_expression of ADHD1 6 0.40 5.06 1.66 72.48
11 INT184853 Gene_expression of ADHD1 87 0.65 89.2 11.8 71.36
12 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82 69.12
13 INT105991 Negative_regulation of IDS 12 0.38 6.31 1.04 66.96
14 INT97062 Binding of PML 10 0.41 11.63 1.65 66.20
15 INT2921 Positive_regulation of F8 53 0.59 41.56 8.56 65.84
16 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 65.84
17 INT109881 Positive_regulation of Gene_expression of F8 11 0.47 12.97 1.54 65.84
18 INT116728 Negative_regulation of ARSH 9 0.13 9.67 0.27 62.08
19 INT335728 Positive_regulation of Dpyd 1 0.17 1.74 0.09 61.12
20 INT155201 Gene_expression of VCP 4 0.75 8.25 0.31 60.40
21 INT167182 Binding of Psd 9 0.41 13.08 1.06 60.36
22 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 56.40
23 INT124774 Binding of Vcp 4 0.44 3.4 0.52 54.16
24 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 50.00
25 INT196991 Negative_regulation of TMEM200A 7 0.28 1.31 0 38.12
26 INT123622 Negative_regulation of Vcp 5 0.42 2.51 0.3 34.04
27 INT219794 Regulation of Gene_expression of Renbp 2 0.08 0.2 0 29.60
28 INT219795 Regulation of Gene_expression of Prf1 1 0.37 0.06 0 29.60
29 INT335731 Gene_expression of Vcp 1 0.73 12.21 0.18 28.44
30 INT14384 Gene_expression of Prf1 9 0.60 3.03 2.22 28.12
31 INT205618 Gene_expression of Renbp 15 0.26 9.26 1.04 28.12
32 INT24459 Positive_regulation of PDB1 7 0.46 7 0.5 22.32
33 INT144767 Gene_expression of UCN2 5 0.65 1.78 1.04 21.84
34 INT335729 Gene_expression of Vmn1r155 1 0.01 2.54 0 20.12
35 INT174106 Binding of Renbp 18 0.24 15.82 0.58 15.60
36 INT219796 Localization of Renbp 1 0.13 0.2 0 15.60
37 INT219797 Localization of Prf1 1 0.61 0.1 0 8.28
38 INT329014 Localization of UCN2 2 0.23 0.14 0.07 7.76
39 INT162 Regulation of Prl 794 0.62 165.01 322.24 5.00
40 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 5.00
41 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 5.00
42 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 5.00
43 INT19 Regulation of Gnrhr 131 0.62 36.4 55.66 5.00
44 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64 5.00
45 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3 5.00
46 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79 5.00
47 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 5.00
48 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 5.00
49 INT49850 Negative_regulation of PDE4A 105 0.58 76.91 26.59 5.00
50 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 5.00
51 INT11014 Phosphorylation of CREB1 72 0.81 26.35 25.64 5.00
52 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37 5.00
53 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09 5.00
54 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 5.00
55 INT635 Negative_regulation of MAOB 51 0.59 24.5 12.66 5.00
56 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41 5.00
57 INT80790 Positive_regulation of Flvcr2 22 0.45 4.92 12.35 5.00
58 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8 5.00
59 INT71633 Negative_regulation of SLC6A3 25 0.59 10.5 10.69 5.00
60 INT93533 Positive_regulation of Tnfsf11 53 0.50 36.93 10.53 5.00
61 INT104441 Binding of NOVA2 72 0.42 16.41 10.51 5.00
62 INT87271 Positive_regulation of Phosphorylation of CREB1 27 0.66 12.87 7.91 5.00
63 INT18190 Regulation of DRD2 11 0.60 9.01 7.63 5.00
64 INT2838 Positive_regulation of Gene_expression of Oxt 27 0.67 6.25 6.83 5.00
65 INT168641 Gene_expression of Iba1 24 0.63 12.21 6.7 5.00
66 INT127 Positive_regulation of ACOT1 16 0.32 5.12 6.57 5.00
67 INT11154 Binding of EGFR 149 0.48 96.23 6.29 5.00
68 INT157932 Positive_regulation of ADHD1 46 0.48 52.18 6.13 5.00
69 INT84572 Gene_expression of Zmat3 67 0.07 37.61 5.86 5.00
70 INT10147 Gene_expression of Serpinc1 28 0.76 17.73 5.77 5.00
71 INT14501 Gene_expression of CST3 28 0.75 25.77 5.16 5.00
72 INT57368 Regulation of ADHD1 39 0.50 42.23 5.01 5.00
73 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 5.00
74 INT168640 Positive_regulation of Gene_expression of Iba1 9 0.33 8.3 4.55 5.00
75 INT84911 Gene_expression of SUGT1 43 0.11 19.85 4.54 5.00
76 INT3530 Regulation of BCHE 18 0.60 5.47 4.12 5.00
77 INT101301 Gene_expression of Aif1 17 0.42 16.43 4.06 5.00
78 INT123752 Regulation of Bax 19 0.60 16.45 4 5.00
79 INT119053 Positive_regulation of SLC6A3 15 0.65 2.51 4 5.00
80 INT4012 Negative_regulation of Psd 23 0.52 14.12 3.81 5.00
81 INT68695 Gene_expression of HTT 63 0.77 44.54 3.69 5.00
82 INT212563 Gene_expression of Adrm1 26 0.13 11.46 3.58 5.00
83 INT39448 Gene_expression of Scr 13 0.67 5.18 2.96 5.00
84 INT27207 Gene_expression of Psd 31 0.73 15.44 2.75 5.00
85 INT124063 Gene_expression of MTHFR 9 0.65 6.22 2.67 5.00
86 INT189863 Gene_expression of DRD4 11 0.68 7.65 2.66 5.00
87 INT61465 Gene_expression of Acp5 22 0.75 7.06 2.55 5.00
88 INT14503 Binding of BCHE 13 0.48 3.95 1.85 5.00
89 INT103496 Gene_expression of Vps52 3 0.39 3.22 1.78 5.00
90 INT94163 Negative_regulation of UCN2 11 0.57 6.86 1.75 5.00
91 INT134915 Binding of Aif1 4 0.36 1.72 1.72 5.00
92 INT157720 Localization of ADHD1 15 0.64 15.84 1.69 5.00
93 INT174107 Binding of Plxna3 4 0.21 2.95 1.62 5.00
94 INT227500 Negative_regulation of Gene_expression of ADHD1 5 0.34 4.9 1.32 5.00
95 INT197143 Positive_regulation of Renbp 15 0.33 9.41 1.31 5.00
96 INT39447 Negative_regulation of Scr 5 0.37 1.6 1.23 5.00
97 INT101302 Positive_regulation of Gene_expression of Aif1 5 0.37 3.56 1.23 5.00
98 INT145488 Regulation of Cyp2d4 5 0.45 1.1 1.19 5.00
99 INT61466 Positive_regulation of Acp5 15 0.66 10.17 1.16 5.00
100 INT11266 Positive_regulation of UMOD 2 0.43 1.25 1.16 5.00
101 INT36064 Binding of CST3 14 0.47 16.38 1.12 5.00
102 INT303287 Gene_expression of Tardbp 4 0.77 44.78 1.09 5.00
103 INT60970 Positive_regulation of Scr 9 0.59 12.21 1.03 5.00
104 INT335723 Negative_regulation of Gene_expression of Iba1 2 0.47 1.97 0.98 5.00
105 INT161766 Localization of Psd 7 0.75 3.53 0.96 5.00
106 INT292763 Localization of Tardbp 6 0.80 12.51 0.91 5.00
107 INT59884 Gene_expression of UMOD 4 0.78 2.32 0.82 5.00
108 INT157302 Positive_regulation of Map1lc3a 27 0.66 11.31 0.79 5.00
109 INT287087 Localization of EEC1 2 0.61 1.6 0.72 5.00
110 INT78183 Negative_regulation of Adrm1 8 0.09 3.4 0.65 5.00
111 INT47553 Gene_expression of ARSH 11 0.42 4.93 0.65 5.00
112 INT242371 Regulation of Gene_expression of ADHD1 3 0.37 5.2 0.65 5.00
113 INT219793 Negative_regulation of Renbp 5 0.13 3.42 0.61 5.00
114 INT299945 Negative_regulation of Localization of EEC1 1 0.06 1.33 0.53 5.00
115 INT196995 Gene_expression of TMEM200A 22 0.45 4.02 0.53 5.00
116 INT211905 Negative_regulation of RIOK3 2 0.07 2.25 0.48 5.00
117 INT170334 Gene_expression of IGHD2-15 3 0.14 0.75 0.44 5.00
118 INT250468 Positive_regulation of Gene_expression of Adrm1 2 0.04 2.26 0.44 5.00
119 INT335733 Positive_regulation of Tardbp 8 0.69 28.41 0.41 5.00
120 INT98739 Gene_expression of Fbrs 6 0.52 4.77 0.4 5.00
121 INT62507 Regulation of Scr 3 0.16 2.45 0.4 5.00
122 INT196993 Binding of TMEM200A 9 0.22 1.76 0.39 5.00
123 INT38569 Gene_expression of CAPRIN1 2 0.04 0.18 0.39 5.00
124 INT151400 Binding of JAG1 14 0.37 7.96 0.39 5.00
125 INT242395 Positive_regulation of Positive_regulation of Scr 2 0.19 1.93 0.38 5.00
126 INT324332 Binding of UMOD 7 0.41 7.07 0.35 5.00
127 INT207064 Gene_expression of Fkbp1a 2 0.32 1.52 0.34 5.00
128 INT299942 Gene_expression of Synj2bp 1 0.01 1.3 0.32 5.00
129 INT299944 Regulation of Gene_expression of Synj2bp 1 0.01 1.31 0.32 5.00
130 INT310681 Negative_regulation of ARSB 1 0.56 6.95 0.29 5.00
131 INT158730 Gene_expression of Plxna3 4 0.65 1.82 0.29 5.00
132 INT335724 Positive_regulation of Localization of Tardbp 3 0.47 4.9 0.25 5.00
133 INT282635 Positive_regulation of Binding of ADHD1 4 0.40 3.62 0.24 5.00
134 INT83230 Negative_regulation of Prf1 2 0.35 0.29 0.23 5.00
135 INT250467 Localization of Adrm1 2 0.06 0.97 0.19 5.00
136 INT250469 Positive_regulation of Localization of Adrm1 2 0.04 0.97 0.19 5.00
137 INT259536 Transcription of Psd 2 0.38 1.25 0.16 5.00
138 INT50083 Binding of SLC12A1 2 0.01 1.01 0.15 5.00
139 INT335734 Binding of Sh2b1 1 0.06 0.83 0.13 5.00
140 INT332757 Regulation of Binding of ADHD1 1 0.34 1.71 0.13 5.00
141 INT237045 Positive_regulation of Vcp 7 0.62 6.96 0.12 5.00
142 INT263130 Phosphorylation of PDE4A 2 0.42 0.67 0.11 5.00
143 INT189998 Regulation of Prf1 2 0.22 0.44 0.1 5.00
144 INT283245 Gene_expression of MND1 2 0.11 1.94 0.07 5.00
145 INT189864 Positive_regulation of Positive_regulation of ADHD1 3 0.44 3.43 0.07 5.00
146 INT110764 Negative_regulation of Tbt1 2 0.09 1.08 0.05 5.00
147 INT189862 Gene_expression of OSR1 2 0.10 3.62 0.04 5.00
148 INT310678 Protein_catabolism of ARSH 1 0.06 1.76 0.04 5.00
149 INT310683 Protein_catabolism of ARSB 1 0.73 1.85 0.04 5.00
150 INT310682 Regulation of ARSB 1 0.43 0.98 0.04 5.00
151 INT310679 Positive_regulation of ARSB 1 0.39 2.36 0.04 5.00
152 INT335726 Regulation of Vcp 2 0.22 1.94 0.03 5.00
153 INT335740 Negative_regulation of VCP 1 0.41 1 0.03 5.00
154 INT335730 Positive_regulation of Map1lc3b 1 0.53 1.86 0 5.00
155 INT335741 Regulation of VCP 1 0.44 0.26 0 5.00
156 INT324326 Transcription of Scr 1 0.25 0.15 0 5.00
157 INT272956 Positive_regulation of Binding of Psd 1 0.28 2.66 0 5.00
158 INT335722 Localization of Map1lc3b 1 0.61 0.34 0 5.00
159 INT324328 Regulation of Positive_regulation of Scr 1 0.16 1.3 0 5.00
160 INT335727 Gene_expression of Map1lc3b 1 0.59 0.57 0 5.00
161 INT324331 Binding of SHROOM3 1 0.29 1.41 0 5.00
162 INT347732 Binding of Shc2 1 0.14 0.58 0 5.00
163 INT335725 Negative_regulation of Gene_expression of Vcp 1 0.55 0.99 0 5.00
164 INT324329 Negative_regulation of Binding of Scr 1 0.16 0 0 5.00
165 INT335732 Positive_regulation of Gene_expression of Vcp 1 0.57 0.87 0 5.00
166 INT349605 Transcription of ADHD1 3 0.57 3.62 0 5.00
167 INT313268 Binding of Scr 2 0.26 2.93 0 5.00
168 INT324333 Transcription of CST3 1 0.67 0.2 0 5.00
169 INT324327 Positive_regulation of Binding of Scr 1 0.18 1.29 0 5.00
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