D:Dysmenorrhea

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Disease Term
Synonyms Adenomyosis, Adenomyotic, Amenorrhea Syndrome, Amenorrhoea Syndrome, DISMENNOREA, DISMENNORHEA, Dismennorhoea, DISMENNOROEA, DISMENNORRHEA, DISMENNORRHOEA, DISMENOREA
Documents 4502
Hot Single Events 200
Hot Interactions 50

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Dysmenorrhea. They are ordered first by their relevance to Dysmenorrhea and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT133109 Pc Positive_regulation of Pla2g6 1 0.34 0.28 0.28 100.00
2 INT71309 Il1a Positive_regulation of Nos2 1 0.21 0.26 0.26 100.00
3 INT327382 Oxt Positive_regulation of Positive_regulation of Oxtr 1 0.30 0.41 0.2 100.00
4 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 0.65 0.73 0.73 99.82
5 INT42560 OXTR Positive_regulation of Gene_expression of PGF 1 0.50 0.36 0.36 99.28
6 INT312803 F2 Positive_regulation of NPEPPS 1 0.01 1.32 0.32 99.24
7 INT312802 F2 Positive_regulation of Binding of NPEPPS 1 0.01 1.33 0.32 99.24
8 INT42067 Rln1 Positive_regulation of Phosphorylation of Myo1f 1 0.11 0.1 0.1 98.60
9 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14 98.16
10 INT45738 TRH Positive_regulation of TRH Regulation of Prl 2 0.51 0.61 0.17 98.00
11 INT43332 Positive_regulation of Binding of Oxt and Ptgfr 1 0.02 0.37 0.37 97.98
12 INT169507 Oxt Regulation of Gene_expression of Oxtr 2 0.20 0.84 0.38 97.84
13 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83 97.80
14 INT43331 Binding of Oxt and Ptgfr 1 0.01 0.37 0.37 97.78
15 INT25036 TRH Regulation of Prl 4 0.27 1.75 1.09 97.72
16 INT35685 TYR Regulation of Oxt 1 0.14 0.32 0.36 97.64
17 INT340175 Oxt Positive_regulation of Avpr1a 1 0.17 0.56 0.14 97.10
18 INT159596 Binding of IL18 and IL18R1 1 0.08 0.17 0.17 97.00
19 INT32303 Ptger2 Regulation of Ptgfr 1 0.03 0.1 0.1 96.92
20 INT50827 RLN1 Positive_regulation of CSN3 1 0.28 0.1 0.22 95.16
21 INT50826 RLN1 Positive_regulation of PIRT 1 0.01 0.1 0.22 95.16
22 INT157957 Ppyr1 Negative_regulation of Phosphorylation of PLCB1 1 0.00 0.24 0.24 94.68
23 INT147071 NFKB1 Regulation of Gene_expression of PTGES 1 0.36 0.35 0.57 94.68
24 INT340177 Binding of Oxt and Avpr1a 6 0.15 2.24 0.29 94.00
25 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64 93.68
26 INT148342 Hsd17b6 Negative_regulation of Oxt 1 0.21 0.37 0.31 93.28
27 INT340179 Binding of Oxt and Oxtr 10 0.31 2.53 0.19 93.28
28 INT141109 Sftpa1 Positive_regulation of Mapk1 1 0.77 0.65 0.27 93.04
29 INT141113 Sftpa1 Negative_regulation of Sftpa1 Positive_regulation of Ptgs2 1 0.46 0.32 0.14 92.72
30 INT141110 Negative_regulation of Sftpa1 Positive_regulation of Mapk1 1 0.47 0.31 0.14 92.44
31 INT141112 Negative_regulation of Sftpa1 Positive_regulation of Ptgs2 1 0.39 0.31 0.14 92.44
32 INT95042 Binding of NEUROD1 and Olr1246 1 0.02 0.23 0.51 90.24
33 INT95043 Binding of BHLHE22 and Olr1246 1 0.02 0.23 0.51 90.24
34 INT141111 Sftpa1 Positive_regulation of Ptgs2 1 0.64 0.3 0.14 89.84
35 INT17922 Positive_regulation of Crh Positive_regulation of Fos 1 0.23 0.19 0.17 89.68
36 INT90280 Binding of Ppp1cc and Ppp2ca 1 0.34 0.22 0.22 88.92
37 INT175322 Oxt Positive_regulation of Gene_expression of PTGER2 1 0.00 0.09 0.25 88.88
38 INT327385 Binding of TNF and Il13 1 0.09 0.6 0.18 87.56
39 INT175321 IL6 Positive_regulation of Localization of Oxt 1 0.01 0.7 0.25 87.28
40 INT17059 Binding of DLD and Oxt 1 0.03 0.22 0.41 86.96
41 INT116382 Lox Positive_regulation of Binding of Alox5 1 0.12 0.25 0.14 86.20
42 INT106641 Binding of AVP and OXTR 1 0.22 0.47 0.16 85.88
43 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09 85.36
44 INT180670 Cpd Regulation of Protein_catabolism of Ecm1 1 0.04 0.14 0.22 85.04
45 INT209151 OXT Positive_regulation of PNLIP 1 0.08 0.73 0.99 84.24
46 INT209152 Regulation of OXT Positive_regulation of PNLIP 1 0.05 0.42 0.54 84.24
47 INT40452 Binding of OXT and PTGFR 1 0.29 0.08 0.08 83.56
48 INT4904 Oxt Regulation of Ina 1 0.03 0.08 0.21 81.60
49 INT127663 IRF6 Positive_regulation of PDE4A 1 0.14 0.76 0.48 81.44
50 INT327379 S100a8 Regulation of Oxt 1 0.00 0.95 0.29 80.64
51 INT142142 F2r Positive_regulation of Phosphorylation of Plcg1 1 0.03 0.08 0 79.76
52 INT45452 Binding of C2 and C3 1 0.34 0.08 0.08 78.08
53 INT116678 Binding of ARRB1 and Oxtr 1 0.13 0.15 0.38 76.20
54 INT142141 Oxt Regulation of Plcg1 1 0.03 0.08 0 75.08
55 INT110474 YY1 Positive_regulation of Positive_regulation of EDN1 1 0.56 0.15 0.53 75.00
56 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 0.25 0.07 0.46 75.00
57 INT110475 EDN1 Regulation of PRKCA 1 0.05 0.07 0.45 75.00
58 INT167002 Pnoc Regulation of Gene_expression of Oxt 1 0.10 0.2 0.25 75.00
59 INT283857 APOA5 Positive_regulation of Positive_regulation of MAPK1 1 0.00 0.6 0.22 74.80
60 INT283860 APOA5 Negative_regulation of MAPK1 1 0.00 0.59 0.21 74.80
61 INT142143 F2r Regulation of Plcg1 1 0.02 0.07 0 74.56
62 INT42066 Rln1 Regulation of Phosphorylation of Myo1f 1 0.05 0.07 0.07 73.60
63 INT211674 Gtf3a Regulation of Positive_regulation of Igj 1 0.01 0.8 0.19 71.72
64 INT351655 Avp Positive_regulation of Agt 1 0.11 0.94 0.07 71.12
65 INT351651 Enpep Positive_regulation of Agt 1 0.22 0.93 0.07 70.76
66 INT27374 Rln1 Regulation of Oxt 1 0.06 0.13 0.07 70.36
67 INT116680 Binding of ADRBK1 and Oxtr 1 0.18 0.14 0.3 70.04
68 INT127664 Negative_regulation of PDE4A Negative_regulation of MMP9 1 0.37 0.76 0.48 69.88
69 INT127665 Negative_regulation of PDE4A Negative_regulation of Transcription of MMP9 1 0.37 0.76 0.48 69.88
70 INT127662 Negative_regulation of PDE4A Negative_regulation of Gene_expression of PTGS2 1 0.15 0.75 0.47 69.88
71 INT38188 PGR Positive_regulation of Gene_expression of ESR1 1 0.42 0.22 0.07 67.20
72 INT324702 PLOD1 Positive_regulation of CGA 1 0.03 1.1 0.1 65.32
73 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21 64.88
74 INT59463 ANTXR1 Negative_regulation of Binding of OXTR and ISYNA1 1 0.00 0.24 0.1 62.16
75 INT59462 F2 Negative_regulation of Binding of OXTR and ISYNA1 1 0.02 0.24 0.1 61.48
76 INT59459 Binding of OXTR and ISYNA1 1 0.05 0.47 0.2 60.84
77 INT180671 Binding of Plat and Regulation of Serpine1 1 0.16 0.06 0.14 59.08
78 INT324732 Positive_regulation of Binding of Prkaca and HR 1 0.00 1.12 0.08 57.24
79 INT324731 Binding of Prkaca and HR 1 0.00 1.11 0.08 56.68
80 INT6641 Negative_regulation of Binding of Avpr2 and Oxtr 1 0.04 0.06 0.23 55.36
81 INT6642 Binding of Avpr2 and Oxtr 1 0.03 0.06 0.23 55.36
82 INT213419 Negative_regulation of FOXF1 Negative_regulation of Gene_expression of HGF 1 0.25 0.15 0.08 55.36
83 INT213418 Negative_regulation of FOXF1 Negative_regulation of Gene_expression of VCAM1 1 0.29 0.15 0.08 54.72
84 INT164227 Binding of PAEP and Tnfrsf11b 1 0.00 1.18 0.77 54.24
85 INT6644 Binding of Avpr1a and Oxtr 1 0.14 0.05 0.23 54.08
86 INT6643 Negative_regulation of Binding of Avpr1a and Oxtr 1 0.16 0.05 0.23 54.08
87 INT137542 CSE Positive_regulation of Oxt 1 0.02 0.25 0.05 51.76
88 INT137541 CSE Positive_regulation of Gene_expression of Oxtr 1 0.23 0.26 0.05 51.76
89 INT56377 AMBP Negative_regulation of Elane 1 0.00 1.43 0.08 50.00
90 INT66774 Binding of Avp and Avpr1a 1 0.21 0 0 50.00
91 INT66773 Oxt Positive_regulation of Positive_regulation of Avp 1 0.24 0.05 0 50.00
92 INT47482 PRL Regulation of Gene_expression of LGALS1 1 0.19 0 0 42.00
93 INT209159 Binding of LHCGR and PDE5A 1 0.01 0 0 37.36
94 INT147073 NFKB1 Regulation of PTGS2 1 0.37 0 0.11 35.68
95 INT147072 NFKB1 Regulation of PTGES 1 0.36 0 0.11 35.68
96 INT351656 Enpep Regulation of Agt 1 0.20 1.2 0 33.72
97 INT124340 Tacr1 Positive_regulation of Tac2 1 0.48 0 0.27 30.56
98 INT59461 OXTR Positive_regulation of Gene_expression of ISYNA1 1 0.07 0.14 0 29.76
99 INT180668 Edn1 Positive_regulation of Gene_expression of Col1a1 1 0.02 0 0.05 29.32
100 INT180667 Edn1 Regulation of Ecm1 1 0.04 0 0.05 29.32
101 INT59458 GTPBP4 Positive_regulation of Gene_expression of ISYNA1 1 0.02 0.14 0 29.08
102 INT59460 F2 Positive_regulation of Gene_expression of ISYNA1 1 0.06 0.14 0 29.08
103 INT308084 Binding of HSPG2 and OXT 1 0.04 0.25 0.23 29.04
104 INT261732 F2 Positive_regulation of F2R 1 0.14 0 0 22.60
105 INT261735 Positive_regulation of F2 Positive_regulation of F2R 1 0.14 0 0 22.60
106 INT324894 Edn1 Positive_regulation of Gene_expression of Mmp3 1 0.07 0.66 0.16 21.92
107 INT327380 Il13 Positive_regulation of Oxt 1 0.29 0.13 0.32 12.80
108 INT324899 Edn1 Positive_regulation of Positive_regulation of Mmp9 1 0.10 0.66 0.16 10.60
109 INT197914 Dlst Positive_regulation of Positive_regulation of S100g 1 0.06 0 0.1 9.12
110 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
111 INT260897 CRH Positive_regulation of Localization of IL8 1 0.24 0.09 1.51 5.00
112 INT181492 NGF Regulation of TRPV1 1 0.21 0.93 1.31 5.00
113 INT181494 TRPV3 Regulation of Gene_expression of NGF 1 0.24 0.7 1.07 5.00
114 INT181493 TRPV4 Regulation of Gene_expression of NGF 1 0.24 0.7 1.07 5.00
115 INT232426 HRH2 Regulation of Localization of PRL 1 0.15 0.38 0.94 5.00
116 INT260894 CRH Regulation of Localization of MMP3 1 0.21 0.36 0.85 5.00
117 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76 5.00
118 INT260895 CRH Regulation of MMP1 1 0.11 0.31 0.74 5.00
119 INT123229 OXTR Regulation of Localization of PRL 2 0.30 0 0.73 5.00
120 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69 5.00
121 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62 5.00
122 INT89902 SST Positive_regulation of Localization of PRL 2 0.40 0 0.61 5.00
123 INT181471 Binding of Il10 and Ptbp1 1 0.05 2.14 0.58 5.00
124 INT175323 Tlr4 Positive_regulation of Gene_expression of TLR2 1 0.02 0.31 0.56 5.00
125 INT232424 VIP Positive_regulation of Localization of PRL 1 0.36 0 0.53 5.00
126 INT274625 OPN1MW Positive_regulation of SOD1 1 0.19 0.29 0.5 5.00
127 INT175326 SERPINH1 Regulation of Pnlip 1 0.00 0.53 0.49 5.00
128 INT327386 TNF Regulation of Gene_expression of Oxtr 1 0.20 0.98 0.45 5.00
129 INT232427 ABAT Regulation of PRL 1 0.08 0.26 0.45 5.00
130 INT232422 VIP Regulation of Gene_expression of PRL 1 0.40 0 0.37 5.00
131 INT296304 Binding of SPIN1 and ENDO1 1 0.03 1.7 0.37 5.00
132 INT232421 Binding of PRL and Positive_regulation of Regulation of ABAT 1 0.09 0 0.37 5.00
133 INT296306 Binding of BGLAP and SPIN1 1 0.05 1.69 0.37 5.00
134 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.1 0.35 5.00
135 INT327381 Il13 Regulation of Gene_expression of Oxtr 1 0.37 0.88 0.35 5.00
136 INT175319 Negative_regulation of Nos2 Negative_regulation of Positive_regulation of Pnlip 1 0.01 0.83 0.34 5.00
137 INT232419 ABAT Positive_regulation of Localization of PRL 1 0.09 0 0.33 5.00
138 INT232425 Binding of ABAT and Positive_regulation of PRL 1 0.09 0.15 0.33 5.00
139 INT232420 PRL Positive_regulation of Regulation of ABAT 1 0.09 0 0.33 5.00
140 INT175330 IL6 Positive_regulation of Gene_expression of CYP19A1 1 0.01 0.97 0.32 5.00
141 INT260893 CRH Positive_regulation of Gene_expression of IL8 1 0.28 0.05 0.31 5.00
142 INT324897 Binding of Ptbp1 and Il1 1 0.01 0.62 0.3 5.00
143 INT260896 CRH Positive_regulation of Localization of MMP9 1 0.15 0.15 0.3 5.00
144 INT247083 Binding of F5 and PLAT 1 0.03 0.88 0.29 5.00
145 INT302467 TIMP1 Positive_regulation of Negative_regulation of COL5A2 1 0.00 1.1 0.29 5.00
146 INT247081 Binding of F5 and F7 1 0.00 0.87 0.28 5.00
147 INT239226 Binding of Edn1 and Ednra 2 0.06 1.59 0.26 5.00
148 INT302468 INCENP Positive_regulation of Gene_expression of MMP9 1 0.01 0.72 0.26 5.00
149 INT327387 TNF Positive_regulation of Oxtr 1 0.15 0.28 0.25 5.00
150 INT327383 Il13 Positive_regulation of Gene_expression of Cd38 1 0.19 0 0.25 5.00
151 INT175324 Hsp90b1 Positive_regulation of TLR2 1 0.00 0.65 0.23 5.00
152 INT175317 Hsp90b1 Positive_regulation of Tlr4 1 0.02 0.66 0.23 5.00
153 INT120376 Bad Positive_regulation of Gene_expression of Oxtr 1 0.08 0 0.22 5.00
154 INT175320 Tlr4 Positive_regulation of Gene_expression of Mmp9 1 0.01 0.54 0.21 5.00
155 INT353808 HLA-DMA Regulation of HLA-B 1 0.00 1.72 0.19 5.00
156 INT247082 Binding of PLAT and PTBP1 1 0.14 0.59 0.18 5.00
157 INT247084 Binding of F7 and H1F0 1 0.00 0.38 0.17 5.00
158 INT175328 FASLG Positive_regulation of FAS 1 0.01 0.9 0.17 5.00
159 INT324898 Ece1 Regulation of Gene_expression of Edn1 1 0.17 0.8 0.14 5.00
160 INT247078 Binding of F5 and PTBP1 1 0.02 0.44 0.14 5.00
161 INT71310 Il1a Positive_regulation of NOS1 1 0.07 0.09 0.11 5.00
162 INT71311 Il1a Positive_regulation of Positive_regulation of NOS1 1 0.07 0.09 0.11 5.00
163 INT230003 Binding of CAMK4 and Hdl1 1 0.00 1 0.1 5.00
164 INT213421 Binding of CXCL2 and SET 1 0.11 0.17 0.1 5.00
165 INT213417 Binding of CCL7 and SET 1 0.11 0.17 0.1 5.00
166 INT213414 Binding of CXCL1 and SET 1 0.10 0.17 0.1 5.00
167 INT213415 Binding of CCL8 and SET 1 0.11 0.17 0.1 5.00
168 INT213420 Binding of IL6 and SET 1 0.10 0.17 0.1 5.00
169 INT229986 Binding of CAMK4 and HSD11B1 1 0.01 1 0.1 5.00
170 INT213416 Binding of CCL2 and SET 1 0.11 0.17 0.1 5.00
171 INT327384 S100a8 Regulation of Gene_expression of Oxtr 1 0.00 0.1 0.1 5.00
172 INT175325 Binding of TLR2 and Tlr6 1 0.00 0.39 0.09 5.00
173 INT175327 Binding of TLR2 and Tlr1 1 0.00 0.39 0.09 5.00
174 INT287174 Binding of PGR and SHBG 1 0.18 0.11 0.08 5.00
175 INT205537 ATP8A2 Negative_regulation of Negative_regulation of RHOXF2 1 0.01 0 0.07 5.00
176 INT247079 Gene_expression of PLAT Positive_regulation of Gene_expression of PLG 1 0.36 0.3 0.07 5.00
177 INT324896 Ece1 Positive_regulation of Negative_regulation of Edn1 1 0.19 0.42 0.07 5.00
178 INT328834 MTX1 Negative_regulation of KCNK4 1 0.01 0 0.05 5.00
179 INT209155 MMP9 Negative_regulation of TIMP1 1 0.01 0.17 0.05 5.00
180 INT209157 MMP9 Negative_regulation of MMP2 1 0.00 0.16 0.05 5.00
181 INT308432 Binding of PDE4A and Aip 1 0.05 3.1 0.05 5.00
182 INT209156 MMP2 Negative_regulation of TIMP1 1 0.00 0.17 0.05 5.00
183 INT197917 Binding of ESR1 and Sh2b2 1 0.01 0 0.04 5.00
184 INT207997 Bel Regulation of Gene_expression of Plg 1 0.00 0 0.04 5.00
185 INT351652 Enpep Positive_regulation of Positive_regulation of Agt 1 0.19 0.05 0.04 5.00
186 INT247080 Binding of CRH and CRHBP 1 0.11 0.2 0.03 5.00
187 INT261727 TNF Regulation of COL5A2 1 0.05 0.21 0.03 5.00
188 INT261728 PSMB6 Negative_regulation of Transcription of F2R 1 0.01 0.17 0.03 5.00
189 INT213422 MITF Negative_regulation of PROC 1 0.00 0.52 0.03 5.00
190 INT261731 PSMB6 Regulation of COL5A2 1 0.00 0.21 0.03 5.00
191 INT351663 Binding of AGT and Agt 1 0.32 0.57 0.03 5.00
192 INT351653 Enpep Positive_regulation of Protein_catabolism of Agt 1 0.22 0.54 0.03 5.00
193 INT247077 CRHBP Regulation of Binding of CRH and CRHBP 1 0.06 0.2 0.03 5.00
194 INT261733 F2 Regulation of COL5A2 1 0.03 0.21 0.03 5.00
195 INT247085 Binding of CRHBP and GHRH 1 0.01 0.2 0.03 5.00
196 INT260267 Binding of TFAM and TP53 2 0.37 2.1 0.03 5.00
197 INT283862 Binding of CALD1 and MYH14 1 0.02 0 0 5.00
198 INT197903 Dlst Positive_regulation of S100g 1 0.04 0 0 5.00
199 INT211671 Gtf3a Regulation of Tnni2 1 0.01 0.33 0 5.00
200 INT261729 COL5A2 Regulation of Gene_expression of F2R 1 0.18 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Dysmenorrhea. They are ordered first by their pain relevance and then by number of times they were reported in Dysmenorrhea. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 100.00
2 INT3028 Negative_regulation of Oxt 76 0.58 18.52 24.4 100.00
3 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 100.00
4 INT17974 Positive_regulation of Localization of Oxt 34 0.69 4.45 12.9 100.00
5 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91 100.00
6 INT214 Localization of AVP 370 0.81 208.51 91.09 100.00
7 INT76892 Gene_expression of FGFR1 45 0.69 23.6 7.56 100.00
8 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 100.00
9 INT8545 Negative_regulation of MUC16 19 0.57 15.96 2.81 100.00
10 INT24670 Gene_expression of FGF2 121 0.78 85.64 15.12 100.00
11 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 100.00
12 INT99289 Localization of STS 8 0.79 6.5 0.92 100.00
13 INT169706 Positive_regulation of Gene_expression of Itk 2 0.32 2.08 0.81 100.00
14 INT128402 Negative_regulation of Phosphorylation of Gja1 1 0.58 0.73 0.73 100.00
15 INT90276 Gene_expression of Ppp1cc 10 0.73 0.83 2.87 100.00
16 INT97904 Negative_regulation of Gene_expression of FGFR1 1 0.38 0.92 0.55 100.00
17 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 100.00
18 INT23010 Positive_regulation of CYP19A1 28 0.58 24.18 5.37 100.00
19 INT10849 Negative_regulation of OXT 14 0.48 2.51 4.19 100.00
20 INT2148 Negative_regulation of Oxt 105 0.59 11.42 57 100.00
21 INT69321 Regulation of Gene_expression of PTGS2 27 0.61 13.27 9.53 100.00
22 INT92140 Negative_regulation of GALT 1 0.57 0.74 0.56 100.00
23 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 100.00
24 INT86908 Negative_regulation of MLH1 7 0.43 6.98 1.12 100.00
25 INT86909 Negative_regulation of MSH2 9 0.41 12.65 1.7 100.00
26 INT151964 Negative_regulation of W6q5 1 0.01 0.34 0.43 100.00
27 INT28642 Gene_expression of CXCR2 60 0.78 38.69 18.11 100.00
28 INT11890 Protein_catabolism of COL3A1 2 0.77 2.41 0.64 100.00
29 INT97900 Negative_regulation of Gene_expression of FGF2 9 0.57 8.37 1.48 100.00
30 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7 100.00
31 INT103967 Negative_regulation of Gene_expression of BAK1 8 0.42 7.02 1.54 100.00
32 INT8547 Gene_expression of MUC16 116 0.78 75.97 12.18 99.98
33 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 99.98
34 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43 99.98
35 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.98
36 INT140175 Regulation of Kit 23 0.62 8.59 1.79 99.98
37 INT78038 Gene_expression of Oxtr 43 0.78 18.72 9.38 99.96
38 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 99.96
39 INT13823 Gene_expression of Egf 97 0.78 39.99 12.99 99.96
40 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 99.96
41 INT80037 Gene_expression of BAK1 58 0.75 39.49 9.08 99.96
42 INT2893 Localization of Oxt 219 0.80 28.96 79.43 99.92
43 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 99.92
44 INT133106 Positive_regulation of Pla2g6 1 0.47 0.28 0.28 99.92
45 INT30887 Negative_regulation of Ngf 56 0.59 32.96 20.86 99.92
46 INT138406 Gene_expression of Iap1-1 2 0.29 1.94 0.3 99.92
47 INT475 Negative_regulation of Adra1a 28 0.58 7.87 9.83 99.92
48 INT87231 Binding of ECE1 4 0.37 0.47 0.16 99.92
49 INT87232 Regulation of ECE1 1 0.45 0.16 0.1 99.92
50 INT738 Regulation of POMC 459 0.62 111.19 243.74 99.90
51 INT22129 Positive_regulation of Gene_expression of CAT 11 0.67 4.23 2.37 99.90
52 INT9783 Gene_expression of INSRR 81 0.50 32.99 15.52 99.88
53 INT15887 Gene_expression of Nbr1 39 0.77 23.91 7.34 99.88
54 INT66606 Gene_expression of CXCR1 34 0.75 27.79 11.36 99.88
55 INT97903 Negative_regulation of FGFR1 16 0.17 5.6 4.57 99.88
56 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 99.88
57 INT3056 Positive_regulation of Gene_expression of Ptgfr 15 0.40 3.41 2.98 99.88
58 INT1539 Positive_regulation of MSMB 22 0.69 9.42 4.62 99.88
59 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 99.84
60 INT2894 Negative_regulation of Localization of Oxt 43 0.58 4.59 20.85 99.84
61 INT165659 Positive_regulation of Gene_expression of Pak1 1 0.69 2.19 2.19 99.84
62 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 99.84
63 INT120075 Gene_expression of Itk 11 0.43 6.39 1.27 99.84
64 INT92826 Gene_expression of Esrrb 3 0.75 1.58 1.18 99.84
65 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 99.84
66 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25 99.84
67 INT63822 Gene_expression of Mmp23 23 0.43 14.15 5.96 99.84
68 INT1158 Regulation of Agt 106 0.61 29.4 30.29 99.84
69 INT5333 Gene_expression of NPEPPS 45 0.65 26.34 15.25 99.84
70 INT129726 Regulation of Nfkbia 2 0.06 1.63 1.05 99.84
71 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17 99.84
72 INT48235 Negative_regulation of NPEPPS 72 0.46 44.54 25.03 99.84
73 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53 99.84
74 INT3046 Gene_expression of LGALS1 20 0.75 12.48 1.11 99.84
75 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 99.82
76 INT26815 Regulation of OXT 15 0.46 5.38 8.31 99.82
77 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05 99.82
78 INT34232 Regulation of TIMP1 37 0.61 18.76 6.05 99.82
79 INT35246 Binding of PTGFR 2 0.23 0.82 0.37 99.82
80 INT36772 Positive_regulation of Positive_regulation of Oxt 11 0.69 1.73 3.94 99.80
81 INT26585 Gene_expression of Vim 117 0.77 39.97 6 99.80
82 INT169707 Regulation of Gene_expression of Vim 3 0.29 1.11 0.88 99.80
83 INT169703 Positive_regulation of Gene_expression of Vim 7 0.38 2.56 1.09 99.80
84 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71 99.80
85 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18 99.80
86 INT83213 Regulation of Gene_expression of Mki67 3 0.24 2.17 0.39 99.80
87 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 99.78
88 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88 99.78
89 INT148403 Positive_regulation of Chrm2 17 0.42 7.74 2.19 99.78
90 INT28094 Binding of PTH 29 0.37 13.57 3.09 99.78
91 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3 99.76
92 INT77639 Phosphorylation of Plcg1 5 0.68 0.47 0.97 99.76
93 INT209154 Negative_regulation of Positive_regulation of PNLIP 1 0.15 0.5 0.5 99.76
94 INT36188 Positive_regulation of PNLIP 7 0.68 5.99 1.6 99.76
95 INT67612 Binding of PPARG 38 0.48 22.67 8.94 99.76
96 INT142137 Regulation of Phosphorylation of Plcg1 1 0.37 0.1 0.19 99.76
97 INT32431 Gene_expression of HTC2 17 0.75 9.72 1.93 99.74
98 INT51149 Positive_regulation of Gene_expression of INSRR 5 0.17 2.94 1.86 99.74
99 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 99.72
100 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95 99.72
101 INT159607 Transcription of IL18BP 1 0.44 0.41 0.35 99.72
102 INT98983 Gene_expression of IL18R1 6 0.13 2.35 2.22 99.72
103 INT159604 Gene_expression of IL18BP 3 0.49 4.56 2.42 99.72
104 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 99.72
105 INT97899 Positive_regulation of Gene_expression of FGFR1 7 0.62 5.99 0.9 99.72
106 INT70596 Regulation of Uchl1 5 0.39 3.87 3.11 99.70
107 INT3057 Gene_expression of Ptgfr 60 0.58 14.54 11.73 99.68
108 INT1116 Regulation of Ren 103 0.62 27.66 33.26 99.68
109 INT67468 Regulation of SCN5A 27 0.44 4.4 3.47 99.68
110 INT59079 Transcription of PTGS2 30 0.72 14.21 6.52 99.68
111 INT69125 Gene_expression of Prlr 6 0.78 2 1.58 99.64
112 INT63821 Transcription of Mmp7 1 0.53 1.34 1.5 99.64
113 INT69129 Transcription of Prlr 2 0.72 1.13 0.91 99.64
114 INT904 Positive_regulation of Ptgfr 23 0.49 7.98 5.55 99.64
115 INT69127 Positive_regulation of Gene_expression of Prlr 2 0.50 0.57 0.54 99.64
116 INT69126 Positive_regulation of Transcription of Prlr 1 0.47 0.43 0.49 99.64
117 INT21901 Negative_regulation of Egf 25 0.58 10.46 4.99 99.64
118 INT94122 Negative_regulation of Mmp23 21 0.37 15.81 8.03 99.62
119 INT6567 Positive_regulation of Regulation of AVP 2 0.67 0.93 0.51 99.62
120 INT100781 Positive_regulation of Regulation of OXTR 1 0.50 0.49 0.1 99.62
121 INT57201 Localization of ACTA1 2 0.73 1.53 0.56 99.60
122 INT19300 Positive_regulation of OXT 34 0.43 4.43 4.07 99.60
123 INT27964 Negative_regulation of CBR1 12 0.58 5.48 3.74 99.60
124 INT209153 Negative_regulation of Positive_regulation of OXT 1 0.18 0.5 0.5 99.60
125 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.58
126 INT51150 Positive_regulation of HTC2 10 0.67 6.8 2.95 99.58
127 INT42979 Positive_regulation of INSRR 47 0.32 12.24 14.38 99.58
128 INT17619 Regulation of COMT 12 0.45 8.46 12.22 99.58
129 INT3117 Regulation of Oxt 103 0.61 17.93 32.28 99.56
130 INT76706 Positive_regulation of Gene_expression of Ptger3 5 0.22 0.49 2.23 99.56
131 INT21873 Positive_regulation of Gene_expression of Nbr1 5 0.50 2.09 0.51 99.54
132 INT4057 Negative_regulation of Ptgfr 9 0.32 3.28 3 99.54
133 INT87775 Phosphorylation of Gja1 13 0.82 2.75 6.56 99.52
134 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 99.52
135 INT50712 Gene_expression of Comt 13 0.68 6.33 6.23 99.52
136 INT13674 Gene_expression of Cyp1a1 13 0.65 2.22 1.25 99.52
137 INT134130 Gene_expression of CYP17A1 2 0.65 2.38 0.26 99.52
138 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72 99.50
139 INT69781 Negative_regulation of FGF2 22 0.42 17.25 4.24 99.48
140 INT169728 Negative_regulation of Anxa5 2 0.31 0.33 0.13 99.48
141 INT79060 Gene_expression of NOS2 116 0.78 69.25 34.84 99.44
142 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 99.44
143 INT87978 Positive_regulation of Sp6 2 0.37 0.81 0.95 99.44
144 INT87979 Positive_regulation of Lipi 1 0.08 0.81 0.92 99.44
145 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41 99.42
146 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 99.42
147 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66 99.40
148 INT2520 Negative_regulation of Ca2 271 0.57 72.13 83.71 99.38
149 INT6957 Positive_regulation of OXTR 38 0.70 6.55 7.81 99.36
150 INT5868 Positive_regulation of GNRH1 122 0.69 20.96 32.8 99.36
151 INT2123 Positive_regulation of Gnrh1 209 0.70 24.2 68.97 99.36
152 INT1652 Regulation of Pomc 387 0.62 61.01 186.51 99.36
153 INT27373 Negative_regulation of Rln1 2 0.58 0.24 0.2 99.36
154 INT134821 Gene_expression of Gja3 8 0.77 7.45 4.44 99.36
155 INT134822 Gene_expression of Gja1 18 0.72 4.2 1 99.36
156 INT134819 Positive_regulation of Gene_expression of Gja3 3 0.50 1.68 0.63 99.36
157 INT134820 Positive_regulation of Gene_expression of Gja1 3 0.64 0.84 0.49 99.36
158 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79 99.34
159 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 99.32
160 INT9383 Localization of TRPV1 98 0.81 33.23 46.24 99.32
161 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 99.30
162 INT16869 Positive_regulation of Prl 24 0.70 15.7 7.63 99.30
163 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 99.30
164 INT15888 Positive_regulation of Nbr1 42 0.69 35.76 10.48 99.28
165 INT8546 Positive_regulation of MUC16 99 0.69 74.98 11.26 99.28
166 INT2262 Negative_regulation of Lhb 142 0.59 25.47 44.81 99.28
167 INT11887 Localization of MUC16 16 0.80 10.66 1.26 99.28
168 INT148639 Gene_expression of Uchl1 30 0.59 16.76 11.54 99.28
169 INT36115 Transcription of Uchl1 7 0.60 3.24 3.25 99.28
170 INT905 Regulation of Ptgfr 8 0.35 2.87 2.28 99.28
171 INT2982 Positive_regulation of Gene_expression of CGA 17 0.59 9.08 1.99 99.28
172 INT35539 Positive_regulation of Positive_regulation of Nbr1 2 0.47 2.52 0.41 99.28
173 INT7972 Positive_regulation of Gene_expression of PLOD1 15 0.42 5.73 1.96 99.28
174 INT4362 Positive_regulation of Positive_regulation of Ptgfr 3 0.06 0.41 0.38 99.28
175 INT4361 Regulation of Positive_regulation of Ptgfr 3 0.06 0.28 0.14 99.28
176 INT158 Localization of Prl 2431 0.81 378.96 952.2 99.26
177 INT169704 Regulation of Gene_expression of Cdh1 4 0.35 1.75 1.09 99.26
178 INT96172 Negative_regulation of Gm4817 1 0.05 0.47 0.57 99.26
179 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 99.24
180 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 99.20
181 INT23122 Gene_expression of Ptger3 31 0.72 11.94 11.37 99.20
182 INT144005 Negative_regulation of PRKCB 2 0.28 0.2 0.19 99.20
183 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 99.18
184 INT162 Regulation of Prl 794 0.62 165.01 322.24 99.16
185 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68 99.16
186 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 99.16
187 INT7035 Regulation of CGA 87 0.45 29.04 28.45 99.16
188 INT69128 Regulation of Gene_expression of Prlr 1 0.62 0.66 0.66 99.16
189 INT16235 Positive_regulation of CGB 27 0.70 15.71 4.06 99.16
190 INT74633 Positive_regulation of Negative_regulation of Oxt 1 0.40 0.85 1.74 99.14
191 INT151947 Positive_regulation of MVD 3 0.67 1.53 2.97 99.14
192 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4 99.14
193 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 99.12
194 INT10785 Gene_expression of Prl 35 0.78 20.64 6.7 99.10
195 INT120073 Positive_regulation of Itk 34 0.44 23.45 5.09 99.08
196 INT94433 Negative_regulation of TIMP2 16 0.55 9.38 4.78 99.08
197 INT30857 Binding of OXTR 10 0.48 2.27 2.42 99.08
198 INT95655 Negative_regulation of Gene_expression of MKI67 5 0.41 3.66 0.36 99.08
199 INT95654 Negative_regulation of Gene_expression of SKI 1 0.31 1.32 0.36 99.08
200 INT70756 Gene_expression of Adm 28 0.77 13.33 4.22 99.08
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