D:Dyspepsia

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Disease Term
Synonyms ADULT RUMINATION, Bloating, Dyspepsias, EARLY SATIETY, Epigastric Discomfort, Epigastric Pain, Fullness, Functional Dyspepsia, Gaseousness, Gastric Hyperalgesia, Gastric Hypersensitivity
Documents 4763
Hot Single Events 200
Hot Interactions 36

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Dyspepsia. They are ordered first by their relevance to Dyspepsia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT227324 Binding of fd and Cd14 1 0.01 2.8 1.13 100.00
2 INT66428 Dcc Positive_regulation of Fos 2 0.05 0.39 1.29 98.68
3 INT296456 Gria1 Negative_regulation of Rbm39 1 0.00 0.45 0.57 98.64
4 INT159163 Binding of Esr2 and Regulation of Gper 1 0.41 0.27 0.23 98.60
5 INT100564 CRX Positive_regulation of Fos 1 0.04 0.89 1.06 97.76
6 INT161183 NMS Positive_regulation of Gene_expression of Bdnf 1 0.40 1.3 0.67 96.48
7 INT161184 NMS Positive_regulation of Gene_expression of Ntrk2 1 0.55 1.3 0.67 96.48
8 INT164924 GIP Regulation of GYPC 1 0.07 0.33 0.23 96.08
9 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16 95.84
10 INT218857 INPP5E Regulation of ATP12A 1 0.01 1.95 0.09 95.80
11 INT117604 AKR1C1 Negative_regulation of Positive_regulation of Mpo 1 0.00 1.45 0.78 94.68
12 INT224404 Binding of GYPC and PYY 1 0.04 1.48 1.42 93.32
13 INT146881 NMS Positive_regulation of NMS Regulation of Ngf 1 0.36 0.81 0.43 93.24
14 INT146878 NMS Regulation of Ngf 1 0.23 0.81 0.43 93.24
15 INT297121 Binding of GNB3 and Eps8l3 1 0.00 0.81 0.05 90.20
16 INT144110 PRSS1 Positive_regulation of Gene_expression of IL8 1 0.21 1.38 0.48 89.56
17 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5 89.36
18 INT91449 Gpt Positive_regulation of Got1 1 0.01 3.26 0.26 87.48
19 INT280190 Cbs Regulation of Gene_expression of Hist1h1t 1 0.04 0.58 0.32 86.96
20 INT164923 INS Positive_regulation of GIP 1 0.43 0.18 0.11 84.52
21 INT292090 Negative_regulation of Binding of KIT and TXK 1 0.02 1.54 0.04 82.00
22 INT292085 Negative_regulation of Binding of FLT3 and TXK 1 0.02 1.54 0.04 82.00
23 INT292095 Negative_regulation of Binding of KDR and TXK 1 0.04 1.53 0.04 82.00
24 INT292079 Negative_regulation of Binding of PDGFRB and TXK 1 0.06 1.54 0.04 82.00
25 INT292086 Negative_regulation of Binding of FLT1 and TXK 1 0.04 1.48 0.04 82.00
26 INT292093 Negative_regulation of Binding of FLT4 and TXK 1 0.03 1.53 0.04 82.00
27 INT94939 Binding of POMC and B3GAT1 1 0.40 1.04 0.12 81.68
28 INT94938 Binding of SERPINB1 and B3GAT1 1 0.01 1.04 0.12 81.68
29 INT227325 Binding of IRF6 and Cd14 1 0.01 2.51 0.93 81.56
30 INT292089 Binding of KIT and TXK 1 0.02 1.54 0.04 81.40
31 INT292084 Binding of FLT3 and TXK 1 0.02 1.53 0.04 81.40
32 INT292083 Binding of KDR and TXK 1 0.04 1.52 0.04 81.40
33 INT292092 Binding of PDGFRB and TXK 1 0.05 1.53 0.04 81.40
34 INT292094 Binding of FLT4 and TXK 1 0.02 1.53 0.04 81.40
35 INT292080 Binding of FLT1 and TXK 1 0.04 1.47 0.04 81.40
36 INT126268 Tpsab1 Positive_regulation of F2rl1 2 0.35 1.65 0.88 80.36
37 INT108466 RCBTB1 Positive_regulation of Cck 1 0.01 0.16 0.51 79.76
38 INT108467 GCG Positive_regulation of Cck 1 0.02 0.16 0.51 79.76
39 INT158877 PRS Positive_regulation of Gene_expression of Fos 1 0.09 5.14 1.54 76.76
40 INT154023 Binding of NOVA2 and Comt 1 0.03 0.08 0 76.44
41 INT153533 NMS Regulation of Gene_expression of Ephb1 1 0.48 3.96 1.93 75.00
42 INT146879 CRX Regulation of NMS 2 0.02 1.86 1.17 75.00
43 INT153532 NMS Regulation of Gene_expression of Fos 1 0.23 1.33 0.67 75.00
44 INT146880 CRX Positive_regulation of Ngf 1 0.03 0.78 0.52 75.00
45 INT146877 NMS Positive_regulation of Ngf 1 0.39 0.78 0.52 75.00
46 INT153534 Binding of Ephb1 and NMS 1 0.29 1.13 0.5 75.00
47 INT150333 4930519F16Rik Positive_regulation of F2rl1 1 0.00 0.67 0.38 75.00
48 INT298829 Binding of LCT and SUGT1 1 0.00 0.39 0.11 73.04
49 INT164925 GIP Positive_regulation of Localization of INS 2 0.59 0.86 0.09 70.76
50 INT245343 Prkd1 Regulation of Slc3a1 1 0.29 0.47 0.36 70.16
51 INT161190 CRX Regulation of Gene_expression of Ntrk2 1 0.04 3.05 2.06 68.36
52 INT161187 NMS Regulation of Gene_expression of Ntrk2 1 0.43 3.05 2.06 68.36
53 INT161186 Bdnf Regulation of Gene_expression of Ntrk2 1 0.44 1.05 0.68 68.36
54 INT263230 Prkcg Regulation of Trpv1 1 0.05 0.95 0.56 66.12
55 INT158878 CRX Positive_regulation of Gene_expression of Fos 1 0.02 1.49 0.41 65.88
56 INT203016 CCK Positive_regulation of Localization of PYY 3 0.68 1.19 1.17 65.68
57 INT161188 NMS Regulation of Gene_expression of Rvm 1 0.03 2 1.39 63.40
58 INT161189 CRX Regulation of Gene_expression of Rvm 1 0.00 2 1.39 63.40
59 INT161191 CRX Regulation of Gene_expression of Trib3 1 0.00 2 1.38 63.40
60 INT161185 NMS Regulation of Gene_expression of Trib3 1 0.03 2 1.38 63.40
61 INT275851 PES1 Negative_regulation of CP 1 0.01 1.96 1.83 62.72
62 INT153322 CRH Positive_regulation of Positive_regulation of CRHR1 1 0.31 0.12 0.19 61.84
63 INT263232 Prkcg Positive_regulation of Trpv4 1 0.12 1.1 1.02 61.60
64 INT215904 IL36B Regulation of PRL 1 0.01 0.22 0.03 61.12
65 INT191240 SAE1 Regulation of Localization of INS 1 0.08 1.15 0.3 60.12
66 INT88778 Binding of Oprm1 and Pomc 3 0.21 0.56 1.14 58.92
67 INT138428 Binding of Oprm1 and Pomc Positive_regulation of Gene_expression of Pomc 1 0.30 0.38 0.7 58.92
68 INT299725 AFP Positive_regulation of Positive_regulation of ACPP 1 0.00 0.78 0.17 58.88
69 INT267686 Binding of RYBP and CENPJ 1 0.01 0.12 0.03 58.08
70 INT159837 Trim2 Negative_regulation of Transcription of Fos 1 0.10 1.92 1.22 55.16
71 INT177359 Serpinc1 Positive_regulation of CSRP1 1 0.00 0.97 0.72 52.44
72 INT157080 Ghrl Positive_regulation of Localization of Gnrhr 2 0.23 0.7 0.26 51.40
73 INT288497 Binding of Tlr7 and Tlr9 1 0.21 0.97 0.27 51.00
74 INT280189 Binding of Cbs and P2rx3 1 0.01 1.03 0.47 50.00
75 INT280188 Binding of Cbs and Trpv1 1 0.26 1.03 0.47 50.00
76 INT223734 Binding of VEGFA and Nos2 1 0.01 0 0 50.00
77 INT314624 Ex Regulation of GCG 1 0.01 0.67 0 49.20
78 INT314621 Ex Regulation of INS 1 0.06 0.67 0 48.48
79 INT323386 Negative_regulation of Binding of Lta and Coq10a 1 0.10 0.57 0 47.80
80 INT180200 Binding of BCAR1 and MMVP1 1 0.11 8.57 0.08 47.56
81 INT323385 Binding of Lta and Coq10a 1 0.09 0.56 0 46.64
82 INT292082 MIR1200 Negative_regulation of KDR 1 0.00 1.24 0 45.44
83 INT292091 MIR1200 Negative_regulation of PDGFRB 1 0.01 1.24 0 45.44
84 INT100084 Binding of CRH and CRHR2 1 0.32 1.11 0.19 43.76
85 INT301079 Binding of GNAT1 and INPP5E 1 0.00 0.59 0.89 40.24
86 INT91720 Binding of BDNF and CNTF 1 0.09 1.71 0.38 36.64
87 INT224406 INS Regulation of Localization of PYY 1 0.11 0.27 0.27 36.48
88 INT224405 INS Regulation of Localization of CCK 1 0.12 0.27 0.27 35.92
89 INT91719 Binding of BDNF and LIF 1 0.09 1.65 0.38 35.36
90 INT313778 Gene_expression of Crhq1 Negative_regulation of Localization of Crh 1 0.05 0.66 0.71 31.92
91 INT245329 ATR Negative_regulation of DCD 1 0.10 0.91 0.05 31.92
92 INT245331 ATR Regulation of IL1B 1 0.03 0.91 0.05 31.92
93 INT245330 ATR Regulation of TNF 1 0.04 0.9 0.05 31.92
94 INT325421 PHF20 Positive_regulation of Localization of Gnrhr 1 0.00 0.39 0.17 30.00
95 INT341624 Binding of CFTR and PRSS1 1 0.39 1.01 0.45 27.36
96 INT208936 Tac1 Positive_regulation of Tacr1 1 0.13 0.39 0.25 25.00
97 INT326605 Binding of HTR1A and KCNH2 1 0.00 0.45 0.14 19.84
98 INT203015 CCK Regulation of Localization of PYY 1 0.24 0.61 0.28 17.80
99 INT342139 MUC7 Positive_regulation of Localization of DNAH8 1 0.00 0.06 0.13 15.64
100 INT264936 Binding of TRGV9 and Ggt1 1 0.02 0.1 0 15.00
101 INT181490 Tryptase Positive_regulation of F2rl1 1 0.13 1.83 1.21 14.48
102 INT181491 Tryptase Positive_regulation of HTR1A 1 0.02 0.93 0.61 14.48
103 INT233771 Binding of KRT7 and KRT20 1 0.01 1.72 0 14.36
104 INT233777 Binding of KRT20 and Cea 1 0.01 3.42 0 14.04
105 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 13.48
106 INT292081 Binding of EDN1 and NCOR2 1 0.00 0.98 0.03 12.84
107 INT343027 Binding of CYP3A4 and Azi1 1 0.02 0.75 0.14 8.04
108 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39 7.56
109 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27 5.00
110 INT296484 Binding of Gria2 and GRIP1 1 0.04 4.52 4.59 5.00
111 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49 5.00
112 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91 5.00
113 INT334928 Binding of pr and Aes 1 0.00 1.49 3.38 5.00
114 INT1151 Binding of CCK and GAST 7 0.49 0.73 3.08 5.00
115 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79 5.00
116 INT210696 Trpv1 Regulation of Slc12a2 1 0.25 1.97 2.58 5.00
117 INT229394 TPSD1 Positive_regulation of F2RL1 2 0.00 3.11 2.14 5.00
118 INT117794 Hpcl1 Positive_regulation of Gene_expression of Fos 3 0.17 0.15 1.98 5.00
119 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92 5.00
120 INT13979 Gast Positive_regulation of Localization of Sst 3 0.69 0.05 1.75 5.00
121 INT139156 Binding of Gria1 and Gria2 1 0.23 0.64 1.72 5.00
122 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53 5.00
123 INT19633 GNRH1 Regulation of Localization of CGA 4 0.44 0.82 1.33 5.00
124 INT107858 PRSS1 Positive_regulation of F2RL1 6 0.12 4.23 1.29 5.00
125 INT70226 Binding of TAC1 and B3GAT1 4 0.24 4.5 1.26 5.00
126 INT281077 Binding of Gria2 and Gria3 2 0.24 0.35 1.19 5.00
127 INT346986 Binding of SHC3 and PAG1 1 0.35 1.02 1.12 5.00
128 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
129 INT296458 Binding of Gria2 and Pick1 3 0.24 1.86 1.07 5.00
130 INT296460 Binding of Gria2 and Myo18a 1 0.01 1.49 1.06 5.00
131 INT262367 Tcas1 Positive_regulation of Localization of Adh4 1 0.01 1.91 1.01 5.00
132 INT263227 Positive_regulation of Prkcg Regulation of Trpv4 1 0.07 0.95 1 5.00
133 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97 5.00
134 INT252877 Prkaca Positive_regulation of Regulation of Grip2 1 0.01 0.22 0.94 5.00
135 INT281085 Binding of Gria2 and Nsf 2 0.26 0.4 0.94 5.00
136 INT186568 Hpcl1 Regulation of Gene_expression of Fos 1 0.22 0.07 0.94 5.00
137 INT252878 Prkaca Regulation of Regulation of Grip2 1 0.01 0.22 0.94 5.00
138 INT252880 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Tacr1 1 0.02 0.29 0.92 5.00
139 INT107001 F2 Positive_regulation of PAR1 4 0.05 2.15 0.92 5.00
140 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91 5.00
141 INT252876 Positive_regulation of Prkaca Regulation of Gene_expression of Tacr1 1 0.01 0.28 0.89 5.00
142 INT252881 Crcp Positive_regulation of Gene_expression of Tacr1 1 0.00 0.28 0.88 5.00
143 INT186567 Negative_regulation of Hpcl1 Positive_regulation of Fos 1 0.11 0.07 0.82 5.00
144 INT208946 Positive_regulation of Tacr1 Positive_regulation of Gene_expression of S100a8 1 0.02 1.11 0.8 5.00
145 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79 5.00
146 INT224403 Binding of CCK and GYPC 1 0.04 0.83 0.77 5.00
147 INT106999 F2 Positive_regulation of PAR4 3 0.06 1.83 0.72 5.00
148 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72 5.00
149 INT263236 DAG1 Positive_regulation of Prkcg 2 0.01 0.31 0.7 5.00
150 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67 5.00
151 INT261517 Binding of HTR2A and USH1C 1 0.01 0 0.66 5.00
152 INT270762 IL1B Positive_regulation of IL1B Negative_regulation of IKBKB 1 0.02 1.13 0.66 5.00
153 INT270763 IL1B Negative_regulation of IKBKB 1 0.04 1.13 0.66 5.00
154 INT186569 Regulation of Hpcl1 Positive_regulation of Fos 1 0.07 0 0.65 5.00
155 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62 5.00
156 INT274167 Il13 Regulation of Il5 2 0.09 2.05 0.59 5.00
157 INT296463 Binding of Gria1 and Pick1 1 0.16 0.32 0.59 5.00
158 INT296486 Binding of Pick1 and GRIP1 1 0.03 0.32 0.59 5.00
159 INT296472 Camk2a Positive_regulation of Prkaca 1 0.09 0.32 0.57 5.00
160 INT201512 Binding of PRSS1 and hcp 1 0.09 1.9 0.57 5.00
161 INT296475 Binding of Pick1 and Myo18a 2 0.01 1.63 0.57 5.00
162 INT296446 Binding of Gria2 and Gria4 1 0.13 0.55 0.57 5.00
163 INT173555 TIMP1 Negative_regulation of MMP7 1 0.01 0 0.56 5.00
164 INT173556 TIMP1 Negative_regulation of MMP9 1 0.02 0 0.56 5.00
165 INT187222 Binding of Vip and Vipr2 2 0.19 1.82 0.56 5.00
166 INT173557 TIMP1 Negative_regulation of MMP3 1 0.02 0 0.56 5.00
167 INT173554 TIMP1 Negative_regulation of MMP1 1 0.03 0 0.55 5.00
168 INT296483 Prkca Positive_regulation of Localization of GRIP1 1 0.02 0.31 0.55 5.00
169 INT173553 TIMP1 Negative_regulation of MMP2 1 0.05 0 0.55 5.00
170 INT263231 Positive_regulation of Trpv1 Positive_regulation of Prkcg 1 0.08 0.57 0.55 5.00
171 INT296462 Prkca Positive_regulation of Phosphorylation of Gria2 1 0.15 0.3 0.55 5.00
172 INT177358 Ptger1 Positive_regulation of Localization of AMY2A 1 0.00 0.56 0.54 5.00
173 INT177357 Ptger1 Positive_regulation of Gene_expression of AMY2A 1 0.00 0.56 0.54 5.00
174 INT267707 Binding of Tnf and ARID1B 2 0.20 8.2 0.54 5.00
175 INT263229 Trpv1 Positive_regulation of Prkcg 1 0.08 0.57 0.54 5.00
176 INT296485 Negative_regulation of Binding of Gria2 and GRIP1 1 0.05 0.3 0.54 5.00
177 INT296442 Binding of Gria2 and GRIP1 Positive_regulation of Negative_regulation of Gria2 1 0.05 0.45 0.53 5.00
178 INT278824 Positive_regulation of Binding of EDNRA and EDNRB 1 0.12 1.65 0.53 5.00
179 INT278819 EDNRA Negative_regulation of Binding of EDNRA and EDNRB 1 0.04 1.65 0.53 5.00
180 INT356351 Binding of CALM1 and TNC 1 0.02 0 0.52 5.00
181 INT274170 Il13 Regulation of Il4 3 0.09 2.75 0.51 5.00
182 INT263228 Prkcg Regulation of Trpv4 1 0.07 0.36 0.5 5.00
183 INT263235 Trpv4 Regulation of Trpv1 1 0.17 0.7 0.5 5.00
184 INT296457 Camk2a Positive_regulation of Phosphorylation of Gria1 1 0.19 0.28 0.49 5.00
185 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49 5.00
186 INT173597 Negative_regulation of Binding of MMP2 and Mmp13 1 0.14 0.83 0.48 5.00
187 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48 5.00
188 INT173595 Binding of MMP2 and Mmp13 1 0.12 0.83 0.48 5.00
189 INT173596 Binding of MMP3 and Mmp13 1 0.06 0.84 0.48 5.00
190 INT173598 Negative_regulation of Binding of MMP3 and Mmp13 1 0.06 0.84 0.48 5.00
191 INT296471 Camk2a Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47 5.00
192 INT296487 PRKG1 Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47 5.00
193 INT296466 Prkca Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47 5.00
194 INT296451 Prkaca Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47 5.00
195 INT341622 Binding of F2 and CTRC 1 0.06 1.22 0.46 5.00
196 INT341625 Binding of SPINK1 and CTRC 1 0.41 1.22 0.46 5.00
197 INT341623 Binding of CFTR and CTRC 1 0.35 1.22 0.46 5.00
198 INT203017 Binding of CCK and PYY 1 0.38 0.62 0.43 5.00
199 INT296477 Binding of Cacng2 and Dlg4 1 0.04 0.22 0.42 5.00
200 INT275849 PES1 Positive_regulation of Gene_expression of TNFAIP1 1 0.01 1.28 0.42 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Dyspepsia. They are ordered first by their pain relevance and then by number of times they were reported in Dyspepsia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT109833 Binding of GNB3 7 0.48 8.83 2.84 100.00
2 INT227258 Binding of fd 1 0.05 2.28 1.13 100.00
3 INT227255 Gene_expression of fd 3 0.07 1.58 0.77 100.00
4 INT227257 Positive_regulation of Binding of fd 1 0.05 1.23 0.61 100.00
5 INT227323 Positive_regulation of fd 1 0.01 1.65 0.61 100.00
6 INT248374 Binding of IKBKAP 10 0.42 10.45 1.9 100.00
7 INT227256 Regulation of fd 1 0.05 0.98 0.46 100.00
8 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 100.00
9 INT134328 Binding of B3GNT3 4 0.05 2.22 1.01 100.00
10 INT283660 Regulation of Positive_regulation of Phax 1 0.03 1.49 0.71 100.00
11 INT11847 Regulation of Plxna3 3 0.44 0.45 0.52 100.00
12 INT60196 Binding of FOS 33 0.47 13.11 6.95 100.00
13 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15 99.98
14 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 99.98
15 INT61893 Gene_expression of Ghrl 125 0.75 71.49 15.14 99.92
16 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 99.90
17 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 99.90
18 INT17267 Regulation of Csprs 1 0.22 0.28 0.26 99.88
19 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 99.84
20 INT99163 Positive_regulation of Cd14 18 0.49 16.02 7.91 99.84
21 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35 99.84
22 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 99.84
23 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3 99.84
24 INT56224 Negative_regulation of Gene_expression of Ifng 40 0.58 23.34 25.08 99.84
25 INT25222 Positive_regulation of Gene_expression of Ifng 32 0.50 24.18 19.58 99.84
26 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14 99.84
27 INT12476 Negative_regulation of TRPV1 124 0.59 47.95 77.98 99.84
28 INT52775 Positive_regulation of Phax 15 0.42 6.87 11.45 99.82
29 INT103791 Positive_regulation of Positive_regulation of F2rl1 10 0.50 11.24 7.41 99.80
30 INT61664 Regulation of GRIN1 38 0.60 16.45 25.35 99.76
31 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 99.72
32 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.72
33 INT160378 Protein_catabolism of Trpv1 2 0.89 0.61 0.73 99.70
34 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61 99.68
35 INT188282 Regulation of Gene_expression of Ghrl 16 0.31 10.08 1.95 99.66
36 INT157188 Positive_regulation of Gene_expression of Il13 3 0.05 4.94 2.79 99.64
37 INT105197 Negative_regulation of GTS 14 0.37 3.88 17.14 99.64
38 INT1153 Negative_regulation of FUT3 17 0.38 8.61 2.21 99.64
39 INT628 Negative_regulation of GAST 10 0.58 4.44 2.08 99.64
40 INT35242 Negative_regulation of MBL2 17 0.48 12.53 1.73 99.56
41 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46 99.56
42 INT247102 Binding of MBL2 16 0.38 14.18 1.54 99.52
43 INT86950 Negative_regulation of Gene_expression of Il10 26 0.42 18.92 12.73 99.52
44 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24 99.52
45 INT153958 Negative_regulation of Phosphorylation of GRIN1 1 0.57 0.62 1.06 99.52
46 INT8881 Regulation of Gene_expression of Tacr1 38 0.61 17.49 27.19 99.50
47 INT193939 Binding of PSEN1 10 0.36 6.16 1.93 99.48
48 INT2429 Negative_regulation of Mpo 128 0.59 93.76 39.57 99.44
49 INT5649 Negative_regulation of Positive_regulation of Mpo 31 0.59 26.62 11.92 99.44
50 INT3969 Positive_regulation of Sds 27 0.69 7.52 12.31 99.44
51 INT94189 Positive_regulation of FUT3 11 0.31 6.61 1.5 99.36
52 INT146346 Negative_regulation of Gene_expression of Trpa1 15 0.59 11.76 8.83 99.36
53 INT123584 Gene_expression of Trpa1 176 0.78 83 78.65 99.36
54 INT280196 Positive_regulation of Gene_expression of Hist1h1t 1 0.07 1.62 1.02 99.32
55 INT10019 Binding of CD8A 57 0.36 31.49 10.08 99.28
56 INT167460 Regulation of AHSG 2 0.36 3.85 1.23 99.28
57 INT167461 Gene_expression of AHSG 5 0.75 4.59 1.53 99.28
58 INT329536 Regulation of Gene_expression of AHSG 1 0.26 2.19 0.81 99.28
59 INT280193 Positive_regulation of Gene_expression of Cbs 1 0.69 6.59 3.81 99.26
60 INT75907 Binding of LEP 53 0.46 46.65 8.44 99.26
61 INT2884 Positive_regulation of CCK 66 0.69 25.25 30.6 99.22
62 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 99.20
63 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38 99.18
64 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 99.18
65 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92 99.16
66 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75 99.14
67 INT153959 Phosphorylation of GRIN1 8 0.80 4.07 6.18 99.14
68 INT75434 Gene_expression of Il13 27 0.52 26.19 15.4 99.12
69 INT57720 Localization of IGHG3 33 0.74 20.24 6.25 99.12
70 INT74134 Localization of FCGR2A 1 0.04 0.75 0.38 99.12
71 INT74136 Localization of IGHA1 1 0.63 0.54 0.3 99.12
72 INT12082 Localization of IL6 365 0.81 241.78 105.78 99.12
73 INT45753 Localization of CD40LG 45 0.79 32.31 5.28 99.12
74 INT74135 Localization of FCGR2C 1 0.02 0.27 0.15 99.12
75 INT90849 Gene_expression of F2rl1 55 0.78 31.31 20.65 99.08
76 INT125665 Regulation of Cd14 3 0.38 3.16 0.95 99.08
77 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28 99.08
78 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24 99.08
79 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 99.04
80 INT15752 Positive_regulation of Ema 15 0.40 14.57 2.34 99.04
81 INT19685 Localization of Sult2a1 12 0.70 0.83 2.7 99.04
82 INT159556 Binding of Sult2a1 1 0.32 0.82 0.73 99.04
83 INT48920 Negative_regulation of Ephb1 107 0.57 43.6 51.02 99.04
84 INT103043 Binding of PDE5A 16 0.37 7.79 1.12 99.04
85 INT280194 Regulation of Gene_expression of Cbs 1 0.61 1.54 0.73 99.04
86 INT73572 Positive_regulation of S100A8 10 0.67 6.6 1 99.02
87 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 99.00
88 INT60942 Localization of S100A8 12 0.78 12.23 2.39 99.00
89 INT142201 Positive_regulation of Localization of S100A8 2 0.49 1.21 0.31 99.00
90 INT274290 Binding of Fhl1 3 0.03 1.16 0.1 99.00
91 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 98.98
92 INT147366 Gene_expression of Hist1h1t 15 0.44 9.84 6.67 98.96
93 INT280195 Regulation of Gene_expression of Hist1h1t 1 0.04 1.09 0.63 98.96
94 INT130497 Gene_expression of Cbs 5 0.77 16.93 9.34 98.94
95 INT279572 Gene_expression of MBL2 27 0.64 20.88 1.51 98.92
96 INT157780 Binding of CYP4F22 7 0.03 2.23 1.65 98.92
97 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 98.88
98 INT2408 Regulation of CCK 37 0.61 10.01 26.66 98.84
99 INT5045 Regulation of VIP 26 0.62 7.15 11.61 98.84
100 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 98.80
101 INT13938 Positive_regulation of Nkx1-1 64 0.68 30.83 58.75 98.80
102 INT84330 Negative_regulation of Transcription of Hrh2 1 0.38 0.5 0.25 98.78
103 INT117553 Regulation of MIF 10 0.56 12.76 8.67 98.76
104 INT2385 Gene_expression of MIF 57 0.68 40.74 12.78 98.76
105 INT145971 Localization of Nav1 20 0.81 10.3 18.11 98.76
106 INT50615 Positive_regulation of Positive_regulation of Insrr 11 0.19 5.5 10.05 98.76
107 INT290175 Positive_regulation of Binding of HAL 1 0.11 0.47 0.05 98.76
108 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 98.74
109 INT69153 Positive_regulation of Gene_expression of IL5 22 0.32 23.59 5.7 98.72
110 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 98.72
111 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68 98.72
112 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21 98.72
113 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03 98.72
114 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 98.68
115 INT35743 Regulation of tk 4 0.25 2.39 1.39 98.68
116 INT32117 Binding of us 5 0.23 3.61 3.91 98.68
117 INT153346 Binding of Cd14 11 0.31 8.64 3.06 98.64
118 INT52107 Transcription of IL8 63 0.72 41.66 16.06 98.64
119 INT74716 Negative_regulation of Htr4 4 0.42 2.17 2.72 98.64
120 INT94658 Positive_regulation of F2rl1 51 0.70 33.65 27.46 98.60
121 INT12239 Regulation of Localization of CCK 11 0.62 6.03 6.61 98.58
122 INT4283 Positive_regulation of Cbs 10 0.46 6.85 4.44 98.56
123 INT2463 Localization of CCK 101 0.81 37.54 47.59 98.52
124 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 98.52
125 INT296385 Binding of IDUA 12 0.39 20.73 0.93 98.52
126 INT119233 Positive_regulation of Trpv4 65 0.70 20.21 17.3 98.52
127 INT50308 Binding of Cnr1 61 0.48 14.41 33.52 98.52
128 INT8713 Regulation of Tac1 56 0.60 25.29 45.94 98.52
129 INT156296 Regulation of Trpv4 20 0.45 7.84 4.86 98.52
130 INT101401 Positive_regulation of Transcription of Grin1 6 0.67 2.45 2.6 98.48
131 INT227319 Regulation of Regulation of Cd14 1 0.38 1.07 0.46 98.40
132 INT61171 Gene_expression of S100A8 92 0.76 57.74 9.98 98.40
133 INT281033 Regulation of MBL2 6 0.34 4.96 0.52 98.40
134 INT117855 Negative_regulation of Ghrl 29 0.57 17.52 5 98.40
135 INT323979 Negative_regulation of Negative_regulation of Ghrl 2 0.42 0.98 0.76 98.40
136 INT51180 Regulation of Nkx2-2 5 0.26 2.16 4.14 98.40
137 INT9069 Regulation of Htr3a 29 0.60 6.18 16.55 98.40
138 INT109431 Gene_expression of Trpa1 123 0.78 51.84 59.98 98.36
139 INT162538 Positive_regulation of Gucy2c 2 0.67 3.35 1.37 98.36
140 INT6585 Positive_regulation of Insrr 110 0.52 40.67 89.9 98.36
141 INT49808 Localization of tryptase 11 0.78 8.74 2.67 98.34
142 INT15347 Positive_regulation of Localization of Pomc 81 0.70 28.1 31.01 98.32
143 INT546 Binding of ALB 311 0.48 85.98 60.14 98.32
144 INT30041 Binding of HAL 8 0.35 2.36 0.95 98.32
145 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47 98.28
146 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 98.24
147 INT23126 Regulation of HTR3A 10 0.60 5.42 4.81 98.22
148 INT190894 Gene_expression of Pkn1 6 0.04 3.12 2.15 98.20
149 INT283661 Positive_regulation of Gene_expression of Pkn1 1 0.02 1.22 1.19 98.20
150 INT6437 Binding of YY1 154 0.47 26.3 90.46 98.20
151 INT43985 Regulation of LPA 29 0.62 20.79 3.29 98.20
152 INT134136 Regulation of HIST1H2BG 1 0.02 0.83 0.48 98.16
153 INT52993 Positive_regulation of Gene_expression of Rvm 4 0.40 4.21 4.68 98.16
154 INT75908 Regulation of LEP 77 0.60 60.16 15.19 98.16
155 INT127981 Gene_expression of Trpc1 25 0.77 10.51 11.67 98.12
156 INT35359 Negative_regulation of LCT 23 0.59 9.13 2.29 98.12
157 INT624 Positive_regulation of GAST 28 0.70 15.61 4.73 98.08
158 INT943 Negative_regulation of Cck 205 0.59 38.42 174.78 98.08
159 INT164178 Gene_expression of ADCY10 9 0.65 2.72 0.39 98.00
160 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 97.98
161 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 97.98
162 INT19430 Positive_regulation of IGHA1 10 0.67 6.42 2.58 97.98
163 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 97.98
164 INT19426 Positive_regulation of FCGR2A 4 0.07 1.68 0.85 97.98
165 INT74132 Positive_regulation of FCGR2C 2 0.13 0.72 0.23 97.98
166 INT2366 Binding of Cck 192 0.48 30.64 163.46 97.96
167 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 97.92
168 INT65222 Positive_regulation of OMS 1 0.36 0.65 0.74 97.92
169 INT162 Regulation of Prl 794 0.62 165.01 322.24 97.84
170 INT1438 Localization of Pomc 360 0.81 101.26 116.47 97.84
171 INT5148 Regulation of CD40LG 25 0.44 21.58 4.05 97.84
172 INT54602 Regulation of MCS 22 0.24 10.41 5.75 97.84
173 INT50268 Gene_expression of FBN1 13 0.65 10.73 2.72 97.84
174 INT41009 Gene_expression of Ubd 2 0.52 1.67 1.07 97.84
175 INT316212 Binding of SPRN 1 0.12 0.38 0.1 97.80
176 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 97.76
177 INT122657 Positive_regulation of MTNR1A 9 0.49 4.14 0.76 97.74
178 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 97.68
179 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 97.60
180 INT16764 Transcription of Qrfp 39 0.69 6.29 21.61 97.60
181 INT74747 Positive_regulation of Transcription of Qrfp 3 0.67 2.11 1.9 97.60
182 INT7944 Positive_regulation of Fos 193 0.70 60.69 98.31 97.58
183 INT4460 Regulation of Mpo 44 0.62 31.16 12.11 97.56
184 INT9383 Localization of TRPV1 98 0.81 33.23 46.24 97.52
185 INT8547 Gene_expression of MUC16 116 0.78 75.97 12.18 97.48
186 INT29144 Gene_expression of Rvm 41 0.52 29.23 47.76 97.44
187 INT68216 Binding of NF1 40 0.48 51.24 4.59 97.44
188 INT38906 Transcription of Hrh2 6 0.62 3.11 2.03 97.44
189 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 97.40
190 INT109800 Binding of Esr2 8 0.42 1.79 1.93 97.40
191 INT49436 Binding of TRPV1 145 0.48 38.35 55.08 97.36
192 INT2541 Binding of Calca 200 0.48 67.14 134.62 97.36
193 INT738 Regulation of POMC 459 0.62 111.19 243.74 97.28
194 INT22066 Gene_expression of Phax 40 0.78 22.51 25.91 97.28
195 INT2290 Protein_catabolism of POMC 41 0.99 4.86 23.36 97.28
196 INT30444 Negative_regulation of Protein_catabolism of POMC 4 0.51 2.11 4.53 97.28
197 INT50420 Transcription of Grin1 30 0.71 13.21 18.28 97.24
198 INT52180 Binding of Aes 38 0.42 23.16 6.7 97.20
199 INT158 Localization of Prl 2431 0.81 378.96 952.2 97.16
200 INT23257 Regulation of CRP 127 0.62 100.05 21.87 97.12
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