D:Dyspnea

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Disease Term
Synonyms Breathlessness, Chest Tightness, Difficult Breathing, Difficulty Breathing, Dyspnoea, Feeling Of Suffocation, HUNGER FOR AIR, HYPERVENTILATION, LABORED BREATHING, Laboured Breathing, SHORTNESS OF BREATH
Documents 8020
Hot Single Events 200
Hot Interactions 10

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Dyspnea. They are ordered first by their relevance to Dyspnea and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT320600 TNS3 Regulation of CEBPZ 1 0.29 1.96 0.74 95.76
2 INT315996 Binding of HMI and COPD 1 0.01 1.34 0.05 94.44
3 INT192109 PAH Positive_regulation of Binding of COL7A1 1 0.04 1.45 0.2 94.32
4 INT11684 Binding of CSF2 and IL3 6 0.36 3.3 0.72 93.36
5 INT272012 Binding of TSC1 and Lsamp 1 0.03 2.1 0.08 91.04
6 INT318174 Binding of Crp and Xcl1 1 0.03 1.9 0.22 90.96
7 INT303028 Binding of Pah and MCPH1 1 0.02 1.13 0.16 86.80
8 INT272867 Binding of NLRP1 and COPD 1 0.00 1.07 0 86.48
9 INT175560 Binding of GPER and GHRL 1 0.01 1.14 0.03 85.60
10 INT303600 IGF1 Regulation of Gene_expression of GH1 1 0.39 0.83 0.14 84.16
11 INT221910 Binding of SRI and COPD 1 0.01 1.27 0 77.12
12 INT84622 Binding of RERE and KAL1 1 0.00 1.18 0.07 76.64
13 INT191814 PDLIM7 Positive_regulation of TNFRSF8 1 0.08 1.16 0.08 75.52
14 INT191813 PDLIM7 Positive_regulation of FUT4 1 0.09 1.16 0.08 75.52
15 INT300246 Binding of ABCB6 and HSR 1 0.11 1.86 0.08 74.32
16 INT303007 Binding of Pah and Ptgis 1 0.26 0.99 0.12 73.44
17 INT261841 Mastl Positive_regulation of Trpa1 1 0.00 0.82 1.3 68.56
18 INT334893 ACE Negative_regulation of Gene_expression of AGT 1 0.03 1.41 0.1 67.36
19 INT213207 Negative_regulation of ASAP2 Negative_regulation of PVR 1 0.01 0.45 0.04 66.60
20 INT213206 ASAP2 Negative_regulation of PVR 1 0.01 0.44 0.04 66.20
21 INT321601 Binding of C3 and PRTN3 1 0.00 0.99 0.27 59.24
22 INT321602 Binding of C4A and PRTN3 1 0.00 0.99 0.27 59.24
23 INT347446 CD99 Positive_regulation of Binding of DES 1 0.46 1.01 0.17 58.36
24 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16 58.36
25 INT254640 CGA Positive_regulation of REN 1 0.07 1.51 0.08 57.44
26 INT254641 CGA Positive_regulation of AGT 1 0.17 1.51 0.08 57.20
27 INT254639 CGA Positive_regulation of Gene_expression of AGT 1 0.18 1.51 0.08 57.20
28 INT275557 Negative_regulation of Binding of CXCL10 and Cxcr3 1 0.04 1.09 0.35 56.84
29 INT275554 Binding of CXCL10 and Cxcr3 1 0.03 2.18 0.71 56.28
30 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03 50.32
31 INT244232 Binding of Ccr5 and Ccl4 3 0.17 1.48 0.55 50.32
32 INT275553 Negative_regulation of Binding of Ccr5 and Ccl3 1 0.05 0.73 0.26 50.32
33 INT175596 Binding of ACAT1 and HGF 1 0.01 1.58 0.18 50.24
34 INT240215 Binding of SEC31A and PDIA2 1 0.00 0 0 50.00
35 INT185379 Binding of IRF6 and TLR2 4 0.08 2.88 0.35 47.00
36 INT193013 VHL Regulation of Regulation of EPAS1 1 0.14 1.74 0 46.72
37 INT261845 NGF Positive_regulation of Trpa1 1 0.04 0.73 0.71 45.00
38 INT315187 Binding of SFRP1 and COPD 1 0.01 4.47 0 44.20
39 INT205989 Binding of SLC7A7 and PDAP1 1 0.02 1.77 0 41.76
40 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42 39.84
41 INT261832 Trpv1 Negative_regulation of Trpa1 1 0.10 0.58 0.64 28.40
42 INT261830 Hspg2 Negative_regulation of Trpa1 1 0.01 0.58 0.63 28.12
43 INT61824 Binding of SERPINH1 and CRP 1 0.24 0.63 0.08 27.04
44 INT175561 NAA50 Negative_regulation of PRELID1 1 0.00 0.83 0.1 26.68
45 INT285407 ELF3 Regulation of ICAM1 1 0.03 0.91 0.03 25.60
46 INT193014 VHL Regulation of EPAS1 1 0.20 0.92 0 25.00
47 INT262750 GLYR1 Positive_regulation of THBS1 1 0.01 0.99 0 23.84
48 INT272018 Binding of TSC1 and Tsc2 1 0.17 0.48 0 20.48
49 INT285406 ELF3 Positive_regulation of Binding of ROS1 1 0.08 0.9 0.03 20.16
50 INT232009 Positive_regulation of F12 Negative_regulation of Localization of KNG1 1 0.01 0.19 0.05 19.20
51 INT262751 Binding of PTCH1 and SMO 1 0.25 1.29 0.1 17.44
52 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97 17.08
53 INT278824 Positive_regulation of Binding of EDNRA and EDNRB 1 0.12 1.65 0.53 17.08
54 INT278819 EDNRA Negative_regulation of Binding of EDNRA and EDNRB 1 0.04 1.65 0.53 17.08
55 INT278820 EDNRA Negative_regulation of Binding of EDN1 and EDNRB 1 0.03 1.1 0.35 17.08
56 INT278817 EDNRA Negative_regulation of Binding of EDN1 and EDNRA 1 0.02 0.55 0.18 17.08
57 INT278818 EDNRA Negative_regulation of Binding of EDNRB and EDNRB 1 0.06 0.55 0.18 17.08
58 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67 16.92
59 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49 16.92
60 INT239839 IL18 Positive_regulation of TNF 1 0.11 1.08 0.09 16.68
61 INT228229 Binding of Cd4 and Ntm 1 0.02 1.03 0.03 15.52
62 INT193204 Binding of TMED4 and COPD 1 0.02 0.29 0 13.20
63 INT273197 Binding of BCR and COPD 1 0.03 0.4 0 12.48
64 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62 11.52
65 INT278828 Positive_regulation of Binding of EDN1 and EDNRA 1 0.06 0.51 0.15 11.52
66 INT116124 Binding of AFP and HCC 2 0.20 1.72 0.15 8.00
67 INT244328 ELF3 Negative_regulation of Positive_regulation of SH3GL3 3 0.20 1.26 0.04 5.68
68 INT244329 ELF3 Positive_regulation of Gene_expression of SH3GL3 1 0.27 0.66 0 5.68
69 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
70 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
71 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
72 INT202959 Binding of BAG3 and MCRS1 1 0.11 7.46 3.14 5.00
73 INT202965 Binding of STC2 and BAG3 1 0.02 7.86 2.96 5.00
74 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
75 INT202974 Binding of BAG3 and CPP 1 0.25 6.22 2.73 5.00
76 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 5.00
77 INT202963 Binding of STC2 and CPP 1 0.02 5.16 2.04 5.00
78 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01 5.00
79 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 5.00
80 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 5.00
81 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68 5.00
82 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56 5.00
83 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55 5.00
84 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54 5.00
85 INT202958 Binding of STC2 and MCRS1 1 0.01 3.48 1.44 5.00
86 INT261617 SNRNP70 Regulation of Comt 1 0.01 0.4 1.18 5.00
87 INT202960 Binding of MCRS1 and CPP 1 0.14 2.49 1.13 5.00
88 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
89 INT264988 Binding of CYP2C19 and CYP3A4 1 0.18 0.72 1.09 5.00
90 INT202968 Binding of MCRS1 and CAP1 1 0.03 2.46 1.08 5.00
91 INT264987 Binding of CYP2C9 and CYP3A4 1 0.19 0.71 1.08 5.00
92 INT168529 APP Regulation of FSIP1 2 0.65 2.26 1.07 5.00
93 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98 5.00
94 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96 5.00
95 INT168528 QRFP Regulation of FSIP1 2 0.07 1.32 0.93 5.00
96 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9 5.00
97 INT271780 Zfp560 Negative_regulation of Cpox 1 0.00 0.62 0.86 5.00
98 INT244323 Csf2 Positive_regulation of Gene_expression of Tlr4 1 0.23 1.93 0.85 5.00
99 INT188318 MCPH1 Positive_regulation of Pah 3 0.02 3 0.85 5.00
100 INT287494 CRP Positive_regulation of Gene_expression of CCL2 2 0.30 2.33 0.83 5.00
101 INT187290 Binding of HEY1 and Gtf3a 1 0.00 6.18 0.83 5.00
102 INT261834 Itpr3 Positive_regulation of Prkca 2 0.01 0.33 0.78 5.00
103 INT341816 Binding of CEP68 and Aia1 1 0.02 4.76 0.76 5.00
104 INT202967 MCRS1 Negative_regulation of CPP 2 0.14 2.2 0.73 5.00
105 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72 5.00
106 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67 5.00
107 INT261835 Camk2a Positive_regulation of Prkca 1 0.01 0.32 0.66 5.00
108 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66 5.00
109 INT246336 Fig4 Regulation of Localization of Nts 1 0.18 0 0.66 5.00
110 INT244320 Tlr4 Positive_regulation of Aliq1 3 0.04 4.51 0.64 5.00
111 INT311470 Binding of Crp and Il1 1 0.00 2.44 0.63 5.00
112 INT311466 Binding of Acsl1 and Il1 1 0.00 2.46 0.63 5.00
113 INT311467 Binding of Crp and Acsl1 1 0.00 2.31 0.61 5.00
114 INT202962 CPP Negative_regulation of Positive_regulation of BAG3 1 0.26 1.34 0.61 5.00
115 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61 5.00
116 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6 5.00
117 INT352496 AVP Regulation of Gene_expression of CRS 1 0.27 2.47 0.59 5.00
118 INT202971 Binding of BAG3 and CAP1 1 0.04 1.26 0.59 5.00
119 INT275552 Tlr4 Positive_regulation of Gene_expression of Il1 1 0.00 1.28 0.59 5.00
120 INT202973 Binding of CAP1 and CPP 1 0.05 1.24 0.58 5.00
121 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58 5.00
122 INT202970 Binding of STC2 and CAP1 1 0.00 1.25 0.58 5.00
123 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58 5.00
124 INT202972 Positive_regulation of MCRS1 Negative_regulation of CPP 1 0.16 1.64 0.57 5.00
125 INT202961 MCRS1 Negative_regulation of STC2 1 0.00 1.63 0.57 5.00
126 INT277828 Negative_regulation of Binding of ICAM1 and ITGAL 2 0.22 1.27 0.57 5.00
127 INT137141 Binding of HIVEP1 and ITIH4 2 0.16 1.44 0.56 5.00
128 INT311766 INCENP Negative_regulation of Gene_expression of SLC1A3 1 0.04 0 0.55 5.00
129 INT222691 Negative_regulation of Binding of FLNA and TNF 1 0.14 1.92 0.54 5.00
130 INT222692 Binding of FLNA and TNF 1 0.12 1.92 0.53 5.00
131 INT311767 INS Negative_regulation of Gene_expression of SLC1A3 1 0.52 0 0.52 5.00
132 INT248135 Binding of IDS and ACCS 1 0.09 1.12 0.51 5.00
133 INT202957 CPP Negative_regulation of MCRS1 1 0.14 1.53 0.51 5.00
134 INT271344 MPO Regulation of Protein_catabolism of ACCS 1 0.02 2.42 0.51 5.00
135 INT352031 Binding of NR3C1 and JUND 1 0.10 2.87 0.48 5.00
136 INT244319 Csf2 Positive_regulation of Positive_regulation of Tlr4 1 0.23 1.03 0.48 5.00
137 INT202969 Positive_regulation of SGSM3 Positive_regulation of MCRS1 1 0.02 1.22 0.47 5.00
138 INT202964 SGSM3 Positive_regulation of MCRS1 1 0.03 1.21 0.47 5.00
139 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46 5.00
140 INT306732 Il17a Positive_regulation of Gene_expression of Il2 1 0.09 1.07 0.46 5.00
141 INT275549 Il10 Positive_regulation of Localization of Hand2 1 0.01 1.3 0.46 5.00
142 INT275550 Hand1 Positive_regulation of Localization of Hand2 1 0.00 1.29 0.46 5.00
143 INT306731 Il22 Positive_regulation of Gene_expression of Il2 1 0.12 1.07 0.46 5.00
144 INT261839 Binding of Car2 and Trpv1 1 0.03 0 0.45 5.00
145 INT179432 Binding of pcp and AICDA 1 0.03 3.51 0.43 5.00
146 INT352972 IL4 Negative_regulation of Gene_expression of IL8 1 0.07 1.01 0.43 5.00
147 INT230437 Binding of PDX1 and HRCT1 1 0.04 2.45 0.43 5.00
148 INT352986 IL10 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.43 5.00
149 INT352985 IL4 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.43 5.00
150 INT331799 IL8 Negative_regulation of Mapk14 1 0.01 1.6 0.42 5.00
151 INT259637 Binding of Mmp12 and COPD 2 0.02 1.71 0.4 5.00
152 INT168533 Binding of FSIP1 and Aia1 2 0.01 1.97 0.4 5.00
153 INT299181 Cysltr1 Regulation of Musk 1 0.08 1.21 0.4 5.00
154 INT352970 IL4 Negative_regulation of Positive_regulation of TH1L 1 0.01 0.91 0.4 5.00
155 INT188336 IL6 Positive_regulation of Localization of POMC 1 0.01 0.83 0.4 5.00
156 INT294780 IL6 Positive_regulation of IL10 2 0.10 1.26 0.39 5.00
157 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39 5.00
158 INT273617 Gene_expression of Slc6a4 Positive_regulation of Pah 1 0.02 0.93 0.38 5.00
159 INT198652 F2 Positive_regulation of Gene_expression of CD36 1 0.03 1.32 0.37 5.00
160 INT262760 Binding of TEP1 and CD163L1 1 0.00 1.65 0.37 5.00
161 INT272951 Binding of TNF and Igf1 1 0.14 1.48 0.36 5.00
162 INT272953 Negative_regulation of Binding of TNF and Igf1 1 0.16 1.48 0.36 5.00
163 INT186769 Dep1 Positive_regulation of Gene_expression of IgG 2 0.03 1.3 0.36 5.00
164 INT230438 Binding of PDX1 and HAUS7 1 0.02 2.29 0.35 5.00
165 INT334948 IL6 Positive_regulation of IL6 Regulation of IL1RN 1 0.17 1.11 0.35 5.00
166 INT334951 IL6 Positive_regulation of Regulation of IL1RN 1 0.23 1.11 0.35 5.00
167 INT334947 IL6 Regulation of IL6 Positive_regulation of IL1RN 1 0.10 1.11 0.35 5.00
168 INT170773 Binding of P2RX3 and P2RX2 1 0.07 0.27 0.35 5.00
169 INT272952 Igf1 Positive_regulation of Localization of TNF 1 0.19 1.53 0.35 5.00
170 INT334949 IL6 Regulation of Regulation of IL1RN 1 0.13 1.11 0.35 5.00
171 INT334950 IL6 Regulation of IL1RN 1 0.13 1.11 0.35 5.00
172 INT322208 HRCT1 Positive_regulation of PDX1 1 0.01 1.31 0.34 5.00
173 INT198647 TNF Positive_regulation of HIF1A 1 0.03 2.97 0.34 5.00
174 INT244324 Csf2 Positive_regulation of Tlr4 1 0.23 0.95 0.34 5.00
175 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34 5.00
176 INT353010 Binding of GJA8 and TNF 1 0.02 0.24 0.33 5.00
177 INT244325 Csf2 Regulation of Positive_regulation of Aliq1 1 0.03 1.02 0.33 5.00
178 INT341794 Binding of SUGT1 and CEP68 1 0.00 1.1 0.33 5.00
179 INT198642 GPI Positive_regulation of TNF 1 0.03 0.98 0.33 5.00
180 INT299258 Dep1 Positive_regulation of Hspb8 1 0.00 2.06 0.33 5.00
181 INT303030 Binding of Ednra and MCPH1 1 0.00 1.02 0.32 5.00
182 INT284689 Binding of Tspo and Map3k12 1 0.00 0.59 0.32 5.00
183 INT303005 Binding of Ednra and Pah 1 0.06 1.02 0.32 5.00
184 INT220521 Ugt1a6b Positive_regulation of Cdkn1b 1 0.01 2.38 0.31 5.00
185 INT222690 TNF Positive_regulation of Gene_expression of NPEPPS 1 0.01 1.03 0.3 5.00
186 INT284137 EDNRB Regulation of EDNRA 1 0.07 0.09 0.3 5.00
187 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3 5.00
188 INT272925 Ccl2 Positive_regulation of Gene_expression of Col7a1 1 0.00 0.72 0.3 5.00
189 INT281734 MT1JP Positive_regulation of Localization of IL8 1 0.02 0.64 0.3 5.00
190 INT333398 CFD Negative_regulation of Gene_expression of Pdgfa 1 0.02 0.64 0.3 5.00
191 INT275555 Binding of Ltb4r1 and COPD 1 0.01 1.02 0.3 5.00
192 INT272932 Binding of Mmp9 and COPD 1 0.01 0.78 0.29 5.00
193 INT198640 TNF Positive_regulation of ISYNA1 1 0.04 1.07 0.29 5.00
194 INT190826 ELANE Positive_regulation of Localization of MUC1 1 0.07 0 0.29 5.00
195 INT272930 Positive_regulation of Binding of Mmp1a and COPD 1 0.01 0.79 0.29 5.00
196 INT271350 MPO Positive_regulation of TIMP1 1 0.05 1.66 0.29 5.00
197 INT272933 Binding of Mmp1a and COPD 1 0.01 0.78 0.29 5.00
198 INT353009 Binding of GJA8 and VSIG1 1 0.00 0 0.29 5.00
199 INT272929 Positive_regulation of Binding of Mmp9 and COPD 1 0.01 0.79 0.29 5.00
200 INT319220 FSIP1 Regulation of APP 1 0.29 1.46 0.29 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Dyspnea. They are ordered first by their pain relevance and then by number of times they were reported in Dyspnea. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT70970 Binding of COPD 144 0.42 180.34 18.29 100.00
2 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 100.00
3 INT179760 Binding of IGKV2D-19 5 0.25 6.1 0.98 100.00
4 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08 100.00
5 INT290499 Localization of IGKV2D-19 1 0.43 3.79 0.27 100.00
6 INT150867 Regulation of COPD 54 0.48 71.38 8.8 100.00
7 INT183668 Binding of SGCA 15 0.36 9.86 2.42 100.00
8 INT290498 Protein_catabolism of IGKV2D-19 1 0.38 1.42 0.04 100.00
9 INT9199 Positive_regulation of CEBPZ 111 0.67 30.99 28.45 100.00
10 INT269086 Positive_regulation of IGKV2D-19 2 0.29 1.4 0.08 100.00
11 INT290500 Positive_regulation of Localization of IGKV2D-19 1 0.29 1.26 0.04 100.00
12 INT2405 Negative_regulation of SGCA 15 0.57 6.04 2.45 100.00
13 INT4369 Gene_expression of Ldha 157 0.76 88.12 22.45 100.00
14 INT275603 Regulation of Negative_regulation of COPD 1 0.03 0.88 0 100.00
15 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 100.00
16 INT103580 Negative_regulation of Negative_regulation of HP 1 0.01 0.71 0.24 100.00
17 INT16408 Negative_regulation of Nppb 14 0.53 5.49 3.74 100.00
18 INT103852 Negative_regulation of Thbd 2 0.10 2.03 0.26 100.00
19 INT201130 Localization of AES 31 0.63 25.45 5.12 100.00
20 INT546 Binding of ALB 311 0.48 85.98 60.14 100.00
21 INT1976 Regulation of Gene_expression of Prl 80 0.62 20.19 36 100.00
22 INT45674 Regulation of Gene_expression of Serpina6 3 0.14 0.86 1.14 100.00
23 INT45675 Regulation of Gene_expression of Shbg 6 0.15 4.65 1.03 100.00
24 INT22032 Positive_regulation of Negative_regulation of CEBPZ 4 0.41 0.82 0.81 100.00
25 INT242259 Negative_regulation of Positive_regulation of CEBPZ 4 0.48 1.44 0.59 100.00
26 INT355163 Regulation of Localization of AES 1 0.28 1.13 0 100.00
27 INT355161 Regulation of Localization of RASSF1 1 0.44 1.13 0 100.00
28 INT355162 Regulation of Localization of CDKN2A 1 0.40 1.13 0 100.00
29 INT16396 Negative_regulation of CEBPZ 76 0.48 30.03 21.6 99.98
30 INT88099 Negative_regulation of 3110062M04Rik 5 0.35 1.75 2.4 99.98
31 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 99.92
32 INT45167 Positive_regulation of ASAP1 32 0.60 17.09 1.84 99.90
33 INT134346 Binding of PCS 51 0.37 22.27 5.67 99.88
34 INT48473 Binding of Smcp 5 0.31 5.14 0.24 99.88
35 INT20011 Regulation of NEUROD1 10 0.44 3.83 3.53 99.88
36 INT103581 Negative_regulation of Regulation of HP 1 0.02 0.77 0.22 99.84
37 INT63177 Regulation of HP 71 0.44 39.48 5.86 99.84
38 INT275593 Regulation of PLN 1 0.16 0.45 0 99.84
39 INT1721 Negative_regulation of HP 148 0.42 86.82 16.89 99.82
40 INT97785 Negative_regulation of DYNC1I1 4 0.05 2.29 0.13 99.80
41 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31 99.78
42 INT34058 Gene_expression of FMR1 5 0.75 5.11 0.26 99.74
43 INT59593 Regulation of Gene_expression of NPPA 2 0.41 2.51 0.36 99.72
44 INT16356 Regulation of NPPA 33 0.62 13.24 9.53 99.72
45 INT3602 Negative_regulation of Shbg 148 0.53 69.05 11.65 99.70
46 INT45672 Negative_regulation of Serpina6 5 0.43 1.66 2.08 99.70
47 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 99.70
48 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 99.68
49 INT20415 Binding of LIPH 1 0.34 1.25 0.1 99.58
50 INT103579 Negative_regulation of Positive_regulation of PDYN 2 0.42 1.34 3.77 99.54
51 INT5136 Negative_regulation of PDYN 71 0.59 11.22 51.14 99.54
52 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 99.54
53 INT10049 Negative_regulation of SERPINA1 56 0.59 44.52 9.93 99.52
54 INT103020 Gene_expression of SGCA 22 0.56 14.29 2.75 99.48
55 INT16395 Gene_expression of CEBPZ 30 0.57 11.02 6.66 99.48
56 INT7313 Negative_regulation of CDNF 7 0.05 2.53 2.34 99.44
57 INT19107 Positive_regulation of Tbxa2r 23 0.62 12.54 8.44 99.40
58 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 99.40
59 INT103260 Positive_regulation of Nps 35 0.48 23.8 5.67 99.36
60 INT160556 Gene_expression of TNS3 4 0.60 2.94 1.77 99.32
61 INT29693 Binding of Ahr 11 0.31 13.27 1.23 99.32
62 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 99.32
63 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 99.32
64 INT289310 Protein_catabolism of Serpinb1b 1 0.52 0.7 0.07 99.32
65 INT3301 Positive_regulation of Slc43a3 26 0.55 5.48 10.81 99.28
66 INT54565 Binding of SCLC1 12 0.31 20.41 0.81 99.28
67 INT38668 Regulation of Arsg 1 0.17 0.89 0.1 99.28
68 INT275604 Gene_expression of PLB1 2 0.03 1.62 0.06 99.24
69 INT182891 Positive_regulation of Atp2c1 1 0.43 1.49 0.38 99.24
70 INT17099 Regulation of GPT 9 0.44 5.5 1.2 99.24
71 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 99.16
72 INT218063 Gene_expression of Mcs12 5 0.09 5.3 0.29 99.16
73 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 99.16
74 INT77490 Positive_regulation of Tnnc1 85 0.68 43.54 9.07 99.16
75 INT184624 Localization of CDKN2A 8 0.74 7.87 0.25 99.14
76 INT59954 Localization of RASSF1 3 0.73 3.12 0.07 99.14
77 INT3793 Regulation of CEBPZ 59 0.61 20.91 15.83 99.08
78 INT621 Positive_regulation of SERPINH1 19 0.57 21.52 8.44 99.08
79 INT12916 Gene_expression of Thbd 8 0.58 5.16 1.39 99.02
80 INT9084 Positive_regulation of Nppb 74 0.70 69.77 11.85 99.00
81 INT28325 Negative_regulation of Tst 13 0.51 12.41 3.16 99.00
82 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 98.96
83 INT129227 Binding of DNASE1 4 0.14 2.54 0.54 98.96
84 INT28238 Positive_regulation of Hrct1 5 0.38 3.66 0.5 98.92
85 INT17511 Negative_regulation of PRTN3 19 0.41 12 3.3 98.92
86 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47 98.88
87 INT51269 Gene_expression of HIST2H2AA3 16 0.56 10.16 6.55 98.88
88 INT1939 Localization of Cys1 6 0.73 5.9 0.64 98.88
89 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 98.84
90 INT155218 Binding of ABCB6 18 0.35 13.93 2.25 98.84
91 INT90291 Gene_expression of LMNB1 6 0.38 7.75 0.86 98.80
92 INT77955 Negative_regulation of PCS 55 0.43 39.32 5.76 98.78
93 INT7298 Gene_expression of NPPA 35 0.70 18.23 4.76 98.76
94 INT9516 Negative_regulation of Gabrg1 149 0.53 27.83 91.02 98.76
95 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 98.76
96 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 98.72
97 INT250429 Positive_regulation of Gene_expression of ARMC9 5 0.19 1 0.07 98.72
98 INT33219 Positive_regulation of C5AR1 14 0.67 7.75 2.74 98.70
99 INT300255 Binding of HSR 1 0.31 6.35 0.18 98.68
100 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 98.68
101 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 98.68
102 INT45673 Gene_expression of Serpina6 10 0.53 3.47 3 98.68
103 INT21925 Regulation of PLB1 3 0.37 0.64 0.7 98.64
104 INT22239 Negative_regulation of TAC1 52 0.57 12.96 31.41 98.64
105 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 98.60
106 INT9083 Gene_expression of Nppb 74 0.78 70.96 12.19 98.56
107 INT86437 Binding of IL6 154 0.48 121.22 29.3 98.56
108 INT188433 Negative_regulation of Binding of IL6 6 0.42 2.03 0.56 98.56
109 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71 98.56
110 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 98.52
111 INT37179 Negative_regulation of TNS3 2 0.45 0.63 0.4 98.52
112 INT320601 Negative_regulation of Negative_regulation of TNS3 1 0.33 0.36 0.1 98.52
113 INT45168 Negative_regulation of ASAP1 23 0.58 10.15 2.44 98.50
114 INT78469 Negative_regulation of Man2a1 1 0.42 1.58 0.1 98.48
115 INT12175 Positive_regulation of PDYN 86 0.69 18.27 62.04 98.46
116 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 98.44
117 INT9552 Positive_regulation of TNNI3 209 0.70 128.67 19.15 98.44
118 INT270441 Negative_regulation of Negative_regulation of COPD 3 0.36 4.18 0.23 98.42
119 INT11957 Negative_regulation of LPA 52 0.59 39.09 6.84 98.40
120 INT4663 Positive_regulation of Ada 17 0.69 9.48 7.93 98.28
121 INT184890 Regulation of MCRS1 35 0.22 44.35 13.78 98.26
122 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 98.24
123 INT175563 Negative_regulation of NAA50 9 0.16 11.35 1.53 98.24
124 INT70905 Positive_regulation of EDNRA 49 0.67 24.33 11.79 98.20
125 INT133269 Positive_regulation of PDX1 10 0.54 9.77 1.9 98.20
126 INT59859 Localization of ARSD 11 0.65 9.67 1.88 98.20
127 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 98.16
128 INT163613 Transcription of CSF2 16 0.60 12.98 1.62 98.08
129 INT46833 Positive_regulation of SGSM3 56 0.67 24.49 30.31 98.04
130 INT56651 Binding of HLA-DRB1 58 0.48 52.25 13.68 98.04
131 INT4771 Gene_expression of CGB 23 0.67 14.22 3.42 98.04
132 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 98.00
133 INT254298 Protein_catabolism of AES 6 0.55 9.79 1.43 98.00
134 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 97.94
135 INT43907 Binding of CD79A 28 0.48 28.11 3.04 97.88
136 INT48626 Positive_regulation of Csf3 33 0.66 29.79 7.34 97.88
137 INT212900 Regulation of MAGED2 2 0.21 2.37 0.32 97.88
138 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 97.84
139 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 97.84
140 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81 97.72
141 INT199004 Gene_expression of ARMC9 43 0.58 17.72 1.32 97.72
142 INT135762 Binding of Ear1 2 0.41 1.6 0.18 97.64
143 INT131351 Positive_regulation of Gene_expression of Nppb 2 0.50 13.72 1.14 97.60
144 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 97.60
145 INT289306 Positive_regulation of Serpinb1b 6 0.41 2.83 0.48 97.56
146 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47 97.56
147 INT4786 Gene_expression of GHRL 7 0.78 7.94 1.76 97.56
148 INT157382 Gene_expression of Csi 17 0.58 3.93 0.82 97.56
149 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 97.52
150 INT275598 Regulation of DYNC1I1 4 0.04 1.87 0.36 97.50
151 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 97.48
152 INT304835 Positive_regulation of PMMoV 1 0.09 1.94 0.71 97.44
153 INT66598 Negative_regulation of GPER 8 0.04 3.83 0.72 97.40
154 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 97.36
155 INT148892 Binding of HPS1 13 0.37 19.21 3.35 97.32
156 INT90766 Gene_expression of PCS 93 0.77 40.48 14.51 97.28
157 INT345457 Binding of Rer1 1 0.03 0.62 0.06 97.16
158 INT8539 Negative_regulation of Serpina1a 21 0.58 12.65 3.39 97.12
159 INT175562 Gene_expression of ENHO 1 0.10 2.85 0.37 97.08
160 INT294416 Binding of Serpinb1b 1 0.05 0.89 0.46 97.08
161 INT170625 Binding of SERPINA5 8 0.32 8.42 0.69 97.00
162 INT25 Positive_regulation of LAMC2 19 0.67 8.64 7.06 96.96
163 INT24 Negative_regulation of Positive_regulation of LAMC2 1 0.42 0.55 0.21 96.96
164 INT8205 Negative_regulation of Nppa 77 0.59 26.43 25.72 96.92
165 INT20498 Negative_regulation of Positive_regulation of Nppa 9 0.59 4.5 2.43 96.92
166 INT32533 Negative_regulation of Gene_expression of Nppa 2 0.32 1.93 0.38 96.92
167 INT3881 Positive_regulation of Protein_catabolism of F13A1 21 0.41 20 3.28 96.88
168 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 96.88
169 INT81906 Positive_regulation of Binding of F13A1 8 0.20 6.06 1.15 96.88
170 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 96.88
171 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 96.84
172 INT200554 Positive_regulation of Aliq1 29 0.22 33.02 5.32 96.84
173 INT159472 Localization of NPPB 32 0.79 33.67 3.59 96.80
174 INT147793 Localization of COPD 70 0.64 89.01 7.3 96.76
175 INT27753 Positive_regulation of MMVP1 5 0.43 7.1 0.74 96.76
176 INT70907 Negative_regulation of EDNRA 30 0.36 19.68 5.49 96.72
177 INT68202 Gene_expression of ADA 26 0.68 23.15 5.18 96.72
178 INT28097 Negative_regulation of Wbc1 8 0.11 4.07 0.53 96.72
179 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 96.60
180 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 96.56
181 INT4686 Gene_expression of Cys1 32 0.66 36.24 2.49 96.52
182 INT3286 Positive_regulation of Gpt 90 0.69 45.08 28.34 96.48
183 INT192807 Gene_expression of SSRP1 14 0.49 19.28 1.15 96.44
184 INT212088 Positive_regulation of Gene_expression of SSRP1 3 0.37 3.53 0.41 96.44
185 INT79181 Negative_regulation of GP1BA 2 0.06 2.23 0.8 96.40
186 INT202230 Regulation of UNC5B 4 0.04 2.3 0.49 96.40
187 INT263095 Transcription of COPD 3 0.53 2.78 0.33 96.36
188 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 96.36
189 INT3244 Negative_regulation of eCB 37 0.03 16.69 12.61 96.36
190 INT121493 Gene_expression of XRCC1 55 0.65 73.43 2.76 96.32
191 INT58477 Gene_expression of Chdh 33 0.74 39.48 19.78 96.24
192 INT70962 Positive_regulation of SERPING1 33 0.69 27.32 2.14 96.20
193 INT72924 Negative_regulation of MCRS1 27 0.19 33.59 10.29 96.16
194 INT39866 Gene_expression of RUNX1T1 2 0.65 1.75 0.1 96.08
195 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 96.04
196 INT2605 Regulation of ELANE 39 0.61 18.22 7.11 96.04
197 INT5095 Localization of Ghrh 185 0.81 28.09 62.08 96.00
198 INT46530 Gene_expression of Pthlh 15 0.78 11.23 1.7 95.96
199 INT110257 Negative_regulation of Gene_expression of Pthlh 1 0.19 4.01 0.13 95.96
200 INT19541 Gene_expression of Ptgir 22 0.65 15.42 5.39 95.96
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