D:Ecchymosis

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Disease Term
Synonyms Ecchymoses
Documents 397
Hot Single Events 12
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Ecchymosis. They are ordered first by their relevance to Ecchymosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT97430 Binding of B2M and HLA-B 1 0.00 0.66 0.04 72.48
2 INT61916 Binding of Fcgr1 and IgG2a 1 0.47 0.93 0.12 56.96
3 INT61915 Binding of Fcgr1 and Slc3a2 1 0.02 0.43 0.06 50.64
4 INT266646 HMOX2 Regulation of Gene_expression of Hmox1 1 0.00 0.87 0.2 45.40
5 INT194863 Binding of IL1R1 and IL1RN 5 0.09 2.23 1.64 5.00
6 INT229094 Binding of IL1RN and Il1r1 1 0.01 1.9 1.5 5.00
7 INT229085 IL1RN Negative_regulation of Positive_regulation of IL1R1 1 0.12 1.72 0.68 5.00
8 INT106744 Binding of CRP and EGFL7 2 0.07 2.35 0.51 5.00
9 INT229095 Binding of IL1R1 and Il1r1 1 0.00 0.64 0.5 5.00
10 INT229087 IL1R1 Negative_regulation of ACCS 1 0.03 0.86 0.33 5.00
11 INT229088 IL1R1 Positive_regulation of Gene_expression of IL6 1 0.04 0.45 0.14 5.00
12 INT229089 IL1R1 Positive_regulation of IL6 1 0.03 0.45 0.12 5.00
13 INT222684 TEAD1 Negative_regulation of PROC 1 0.01 0.39 0.05 5.00
14 INT183721 HPN Positive_regulation of MYO7A 1 0.02 1.55 0 5.00
15 INT352689 VAX2 Positive_regulation of HIST1H1B 1 0.01 0.59 0 5.00
16 INT285399 Binding of DEFB1 and HLA-B 1 0.01 1.33 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Ecchymosis. They are ordered first by their pain relevance and then by number of times they were reported in Ecchymosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT22024 Negative_regulation of HBG1 45 0.58 26 6.8 99.32
2 INT9188 Localization of HBG1 12 0.75 8.14 2.24 99.32
3 INT4686 Gene_expression of Cys1 32 0.66 36.24 2.49 98.16
4 INT38327 Negative_regulation of F10 2 0.02 0.8 0.67 97.40
5 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64 97.20
6 INT76728 Binding of Vkorc1 1 0.01 0.1 0.36 96.24
7 INT61910 Binding of Slc3a2 6 0.01 3 0.7 93.28
8 INT6623 Gene_expression of NA 231 0.78 45.78 59.36 93.00
9 INT158070 Localization of Aes 23 0.65 19.93 10.9 91.36
10 INT167964 Gene_expression of Aes 30 0.58 25.41 10.16 89.12
11 INT13696 Regulation of COL3A1 2 0.45 2.97 0.95 85.36
12 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 81.12
13 INT717 Regulation of F2 29 0.61 17.46 6.99 79.88
14 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 79.48
15 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17 79.44
16 INT83887 Gene_expression of HMOX2 10 0.77 7.99 3.85 79.20
17 INT16722 Negative_regulation of MPO 25 0.59 18.55 6.99 78.68
18 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64 77.36
19 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 76.72
20 INT134749 Gene_expression of TEAD1 9 0.48 3.61 3.15 76.40
21 INT96142 Binding of ASPSCR1 4 0.36 3.22 1.31 76.16
22 INT59870 Gene_expression of F3 51 0.65 51.83 14.01 76.00
23 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 75.80
24 INT28528 Gene_expression of MSMB 25 0.65 7.66 3.49 75.32
25 INT10146 Negative_regulation of Vwf 27 0.40 17.11 3.69 73.48
26 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13 69.76
27 INT61911 Negative_regulation of Gene_expression of Fcgr1 1 0.38 0.39 0.07 69.08
28 INT192450 Gene_expression of CLTC 26 0.55 18.82 3.26 68.64
29 INT61912 Gene_expression of Fcgr1 3 0.69 1.13 0.41 68.32
30 INT114330 Binding of MPZ 21 0.32 25.58 2.14 67.00
31 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 66.28
32 INT297020 Positive_regulation of CLTC 5 0.36 3.38 0.41 66.16
33 INT134743 Positive_regulation of TEAD1 6 0.36 5.33 1.14 64.64
34 INT222688 Regulation of Positive_regulation of TEAD1 1 0.32 0.65 0.16 64.64
35 INT116529 Binding of HMOX1 10 0.47 15.38 1.04 64.16
36 INT103327 Gene_expression of F8 45 0.71 32.5 2.12 63.88
37 INT229218 Negative_regulation of Gene_expression of F8 3 0.38 1.62 0.29 63.88
38 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 62.96
39 INT16012 Binding of Rac1 17 0.37 6.9 0.53 62.64
40 INT1562 Localization of Crh 499 0.81 126.74 236.68 61.92
41 INT17618 Gene_expression of B2M 36 0.66 16.39 6.68 60.60
42 INT79191 Positive_regulation of Gene_expression of B2M 3 0.03 2.11 1.08 60.60
43 INT4435 Gene_expression of PIK3C2A 20 0.77 14.43 2.48 60.56
44 INT504 Gene_expression of GPT 42 0.75 27.54 3.99 60.44
45 INT344613 Negative_regulation of Gene_expression of CLTC 2 0.31 1.19 0.37 60.12
46 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 59.80
47 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 59.44
48 INT97431 Gene_expression of Adam7 5 0.44 0.64 1.04 59.36
49 INT64888 Negative_regulation of HBM 52 0.16 34.33 5.45 59.04
50 INT1196 Positive_regulation of Positive_regulation of POMC 51 0.70 15.99 28.58 58.56
51 INT39443 Positive_regulation of Positive_regulation of F2 6 0.70 4.31 1.3 58.36
52 INT45753 Localization of CD40LG 45 0.79 32.31 5.28 58.00
53 INT39444 Negative_regulation of Positive_regulation of F2 7 0.59 5.82 1.42 57.64
54 INT65260 Positive_regulation of Col7a1 95 0.69 61.73 18.42 57.36
55 INT222687 Negative_regulation of Localization of TEAD1 1 0.30 0.39 0 56.00
56 INT222686 Localization of TEAD1 1 0.54 0.39 0 56.00
57 INT8684 Positive_regulation of ANGPTL5 45 0.69 36.29 7.47 55.72
58 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 54.08
59 INT61913 Binding of IgG2a 10 0.47 5.04 1.64 53.36
60 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 52.24
61 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19 52.24
62 INT173587 Protein_catabolism of COL5A2 59 0.32 32.73 8.96 51.24
63 INT315761 Binding of DCR 1 0.32 0.34 0.03 48.88
64 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 48.56
65 INT1931 Positive_regulation of Gene_expression of POMC 116 0.70 37.26 38.67 48.56
66 INT82451 Negative_regulation of HMOX1 18 0.51 13.29 5.74 46.56
67 INT4047 Binding of F13A1 105 0.43 66.54 11.81 44.88
68 INT55647 Binding of Nfasc 5 0.35 5.43 0.94 44.04
69 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 43.80
70 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 43.76
71 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 43.52
72 INT25998 Positive_regulation of SSRP1 5 0.43 2.47 0.07 43.04
73 INT71161 Gene_expression of ITGB3 6 0.26 3.59 1.45 41.12
74 INT49142 Gene_expression of SELP 94 0.75 54.61 11.64 40.88
75 INT68846 Gene_expression of Tfrc 22 0.32 10.1 3.06 40.64
76 INT175828 Regulation of FASTK 1 0.24 1.48 0.11 40.56
77 INT265424 Binding of HRCT1 1 0.04 2.15 0.23 39.76
78 INT443 Localization of POMC 1020 0.81 284.52 443.17 38.96
79 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 38.96
80 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 38.16
81 INT3466 Gene_expression of Ptger1 39 0.75 18.34 15.75 36.88
82 INT212536 Negative_regulation of COL3A1 2 0.57 3.53 0.21 36.00
83 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 34.52
84 INT14397 Gene_expression of Serpinc1 27 0.46 14.54 3.32 34.52
85 INT5205 Localization of AR 43 0.80 12.87 4.63 32.96
86 INT3364 Binding of SGCG 87 0.47 31.93 17.24 30.88
87 INT150422 Positive_regulation of Aes 24 0.43 15.63 8 27.40
88 INT192448 Positive_regulation of Gene_expression of CLTC 5 0.32 3.01 0.33 26.92
89 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 26.80
90 INT137250 Gene_expression of Gzmb 3 0.05 2.78 0.38 26.80
91 INT56032 Positive_regulation of NCAM1 38 0.49 26.01 4.68 25.00
92 INT4683 Negative_regulation of PDXK 17 0.55 12.81 4.39 24.20
93 INT148721 Binding of PSMD1 13 0.31 4.78 1.76 23.64
94 INT11689 Binding of PSMD2 16 0.36 2.77 0.34 23.64
95 INT192449 Binding of CLTC 5 0.23 3.57 0.09 22.08
96 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 21.56
97 INT183722 Gene_expression of HPN 3 0.37 1.63 0.08 21.56
98 INT315762 Negative_regulation of DCR 1 0.50 0.44 0.05 14.80
99 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 14.44
100 INT352696 Positive_regulation of VAX2 1 0.05 0.06 0 12.64
101 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
102 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
103 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 5.00
104 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
105 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 5.00
106 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
107 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 5.00
108 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 5.00
109 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 5.00
110 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
111 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
112 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 5.00
113 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
114 INT6849 Localization of IL1B 229 0.81 112.56 69.63 5.00
115 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
116 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 5.00
117 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 5.00
118 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
119 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
120 INT2774 Binding of Crp 241 0.48 195.89 44.39 5.00
121 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
122 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 5.00
123 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 5.00
124 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 5.00
125 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
126 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 5.00
127 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
128 INT10797 Binding of CYP2D6 86 0.48 15.09 31.16 5.00
129 INT6174 Regulation of Gene_expression of POMC 49 0.61 9.75 27.69 5.00
130 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 5.00
131 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 5.00
132 INT23257 Regulation of CRP 127 0.62 100.05 21.87 5.00
133 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
134 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73 5.00
135 INT170444 Binding of Gopc 172 0.39 45.05 20.71 5.00
136 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 5.00
137 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 5.00
138 INT27670 Negative_regulation of Ace 122 0.57 79.21 18.08 5.00
139 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 5.00
140 INT6480 Positive_regulation of IL1RN 59 0.69 33.7 16.66 5.00
141 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 5.00
142 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82 5.00
143 INT37722 Gene_expression of NCAM1 103 0.75 81.57 14.18 5.00
144 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
145 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 5.00
146 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63 5.00
147 INT12135 Gene_expression of PLEK 62 0.75 34.13 12.47 5.00
148 INT87844 Binding of IL1RN 40 0.41 24.37 11.92 5.00
149 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47 5.00
150 INT92493 Gene_expression of Fdps 19 0.75 11.28 10.08 5.00
151 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 5.00
152 INT102698 Binding of ACCS 54 0.42 66.73 9.06 5.00
153 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82 5.00
154 INT2921 Positive_regulation of F8 53 0.59 41.56 8.56 5.00
155 INT6133 Negative_regulation of Serpinc1 56 0.58 42.8 8.35 5.00
156 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 5.00
157 INT573 Negative_regulation of C3 60 0.59 41.37 7.78 5.00
158 INT10513 Gene_expression of Plat 44 0.76 19.49 7.17 5.00
159 INT1123 Positive_regulation of CD79A 74 0.70 51.96 7.14 5.00
160 INT78182 Positive_regulation of ACCS 43 0.43 46.39 6.78 5.00
161 INT52180 Binding of Aes 38 0.42 23.16 6.7 5.00
162 INT32458 Gene_expression of VWF 57 0.78 28.97 5.56 5.00
163 INT11622 Gene_expression of Coc 26 0.57 10.56 5.52 5.00
164 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 5.00
165 INT28703 Negative_regulation of TFPI 29 0.38 19.81 4.93 5.00
166 INT92199 Negative_regulation of Gene_expression of IL1RN 14 0.58 10.11 4.71 5.00
167 INT81485 Negative_regulation of IL1RN 19 0.57 8.3 4.69 5.00
168 INT26404 Positive_regulation of ATM 15 0.49 10.94 4.39 5.00
169 INT181596 Binding of IL1R1 9 0.36 7.99 4.32 5.00
170 INT75688 Binding of KITLG 24 0.30 11.73 4.06 5.00
171 INT28802 Binding of F2 15 0.47 8.8 3.47 5.00
172 INT3881 Positive_regulation of Protein_catabolism of F13A1 21 0.41 20 3.28 5.00
173 INT55409 Localization of VWF 17 0.80 8.99 3.06 5.00
174 INT111820 Positive_regulation of Fdps 10 0.42 10.63 3.01 5.00
175 INT45673 Gene_expression of Serpina6 10 0.53 3.47 3 5.00
176 INT64437 Gene_expression of IL1R1 9 0.65 6.22 2.99 5.00
177 INT597 Positive_regulation of PON1 26 0.62 19.14 2.87 5.00
178 INT126966 Positive_regulation of IL1R1 8 0.67 6.93 2.84 5.00
179 INT10893 Binding of VWF 27 0.47 25.02 2.82 5.00
180 INT85078 Positive_regulation of PCNA 36 0.49 17.06 2.81 5.00
181 INT11519 Negative_regulation of Coc 8 0.50 3.96 2.74 5.00
182 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64 5.00
183 INT94010 Positive_regulation of Localization of VWF 9 0.70 4.23 2.5 5.00
184 INT80329 Positive_regulation of THBD 12 0.47 20.96 2.45 5.00
185 INT4210 Gene_expression of MB 24 0.78 11.74 2.32 5.00
186 INT10514 Negative_regulation of Gene_expression of Plat 8 0.47 6.22 2.24 5.00
187 INT2544 Localization of PTH 39 0.81 30.55 2.22 5.00
188 INT68243 Regulation of Gene_expression of IgG 10 0.44 4.93 2.04 5.00
189 INT191534 Negative_regulation of EGFL7 10 0.06 7.52 1.98 5.00
190 INT67895 Negative_regulation of IL1R1 7 0.57 5.76 1.9 5.00
191 INT141132 Regulation of ACCS 14 0.29 13.92 1.89 5.00
192 INT85492 Localization of IL1R1 6 0.72 2.44 1.85 5.00
193 INT92311 Regulation of SIL1 7 0.44 6.2 1.61 5.00
194 INT109881 Positive_regulation of Gene_expression of F8 11 0.47 12.97 1.54 5.00
195 INT51635 Negative_regulation of LRTOMT 5 0.41 1.17 1.49 5.00
196 INT54593 Positive_regulation of Gene_expression of TF 16 0.68 9.05 1.43 5.00
197 INT2824 Positive_regulation of HTN1 10 0.40 10.41 1.4 5.00
198 INT22558 Gene_expression of COL3A1 10 0.78 7.22 1.36 5.00
199 INT65261 Regulation of Col7a1 18 0.55 8.7 1.33 5.00
200 INT199004 Gene_expression of ARMC9 43 0.58 17.72 1.32 5.00
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