D:Eisenmenger Complex

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Disease Term
Synonyms COMPLEX EISENMENGER, COMPLEX EISENMENGER S, Eisenmenger S Complex, EISENMENGER S SYNDROME, Eisenmenger Syndrome, Eisenmengers Complex, Eisenmengers Syndrome, Syndrome Eisenmenger, Syndrome Eisenmenger S
Documents 32
Hot Single Events 9
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Eisenmenger Complex. They are ordered first by their relevance to Eisenmenger Complex and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT213207 Negative_regulation of ASAP2 Negative_regulation of PVR 1 0.01 0.45 0.04 33.20
2 INT213206 ASAP2 Negative_regulation of PVR 1 0.01 0.44 0.04 32.80
3 INT230723 ERVW-1 Positive_regulation of Gene_expression of EDN1 1 0.00 1.95 0 18.96
4 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97 5.00
5 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67 5.00
6 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62 5.00
7 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61 5.00
8 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6 5.00
9 INT278824 Positive_regulation of Binding of EDNRA and EDNRB 1 0.12 1.65 0.53 5.00
10 INT278819 EDNRA Negative_regulation of Binding of EDNRA and EDNRB 1 0.04 1.65 0.53 5.00
11 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49 5.00
12 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39 5.00
13 INT278820 EDNRA Negative_regulation of Binding of EDN1 and EDNRB 1 0.03 1.1 0.35 5.00
14 INT278817 EDNRA Negative_regulation of Binding of EDN1 and EDNRA 1 0.02 0.55 0.18 5.00
15 INT278818 EDNRA Negative_regulation of Binding of EDNRB and EDNRB 1 0.06 0.55 0.18 5.00
16 INT278828 Positive_regulation of Binding of EDN1 and EDNRA 1 0.06 0.51 0.15 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Eisenmenger Complex. They are ordered first by their pain relevance and then by number of times they were reported in Eisenmenger Complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT22965 Positive_regulation of Pah 42 0.61 41.41 8.84 100.00
2 INT22966 Negative_regulation of Positive_regulation of Pah 2 0.50 2.03 1.56 100.00
3 INT18025 Binding of Pah 32 0.45 30.72 7.93 99.76
4 INT55002 Gene_expression of ASAP1 46 0.64 22.8 3.2 98.64
5 INT193582 Gene_expression of PVR 21 0.58 14 2.39 98.46
6 INT213221 Negative_regulation of ASAP2 1 0.01 5.83 0.46 97.76
7 INT19158 Gene_expression of PAH 35 0.65 35.81 3.88 83.12
8 INT127460 Positive_regulation of Gene_expression of PAH 5 0.43 4.3 0.5 83.12
9 INT9110 Binding of PAH 32 0.41 42.1 3.1 80.24
10 INT71220 Positive_regulation of Casp1 15 0.38 10.23 5.84 74.88
11 INT73590 Positive_regulation of Positive_regulation of Casp1 2 0.19 1.94 1.28 74.88
12 INT353117 Negative_regulation of Positive_regulation of Casp1 1 0.06 1.25 0 74.88
13 INT20612 Positive_regulation of Asap1 36 0.68 24.35 6.06 74.84
14 INT51803 Negative_regulation of Pde7a 14 0.59 14.98 4.85 72.52
15 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 63.52
16 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 63.36
17 INT32783 Gene_expression of Pah 33 0.60 30.55 6.86 60.88
18 INT230730 Negative_regulation of Gene_expression of Pah 2 0.28 1.54 0.12 57.60
19 INT20611 Gene_expression of Asap1 55 0.65 23.71 14.62 56.96
20 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 55.08
21 INT8661 Positive_regulation of Positive_regulation of EDN1 10 0.66 10.9 1.76 55.08
22 INT150330 Gene_expression of BMPR2 7 0.29 4.22 0.34 49.28
23 INT129971 Regulation of PVR 5 0.60 3.96 0.97 48.48
24 INT213220 Regulation of ASAP2 1 0.01 1.73 0.15 48.48
25 INT61680 Positive_regulation of PVR 23 0.60 23.27 3.86 16.32
26 INT28929 Negative_regulation of PVR 22 0.57 16.64 1.07 16.12
27 INT127459 Negative_regulation of PAH 18 0.56 15.15 1.05 15.20
28 INT119523 Gene_expression of EDNRB 32 0.75 26.47 5.75 15.08
29 INT139515 Positive_regulation of EDNRB 15 0.67 10.35 0.93 6.56
30 INT1635 Gene_expression of Vip 245 0.78 53.36 88.13 5.00
31 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
32 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 5.00
33 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 5.00
34 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 5.00
35 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67 5.00
36 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 5.00
37 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 5.00
38 INT50579 Binding of CYP3A4 84 0.48 17.52 17.45 5.00
39 INT59929 Negative_regulation of CYP2C9 60 0.59 16.33 15.39 5.00
40 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42 5.00
41 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55 5.00
42 INT79556 Gene_expression of GRIN3B 16 0.77 7.71 10.75 5.00
43 INT10184 Regulation of EDN1 44 0.62 23.78 10.06 5.00
44 INT66819 Binding of CYP2C9 41 0.48 8.23 8.76 5.00
45 INT6133 Negative_regulation of Serpinc1 56 0.58 42.8 8.35 5.00
46 INT61599 Positive_regulation of CYP2C9 43 0.69 11.1 8.33 5.00
47 INT32709 Negative_regulation of Hbb 30 0.54 18.27 6.97 5.00
48 INT49468 Negative_regulation of Pah 28 0.55 24.95 6.29 5.00
49 INT11064 Positive_regulation of NPR1 24 0.49 14.63 4.78 5.00
50 INT8786 Negative_regulation of ALDH7A1 27 0.52 12.81 4.76 5.00
51 INT2144 Localization of COL7A1 36 0.74 20.92 4.67 5.00
52 INT504 Gene_expression of GPT 42 0.75 27.54 3.99 5.00
53 INT18881 Binding of Asap1 7 0.41 4.28 3.66 5.00
54 INT45971 Negative_regulation of GOT1 9 0.51 6.2 2.84 5.00
55 INT29651 Regulation of Pah 11 0.37 9.95 2.79 5.00
56 INT100014 Negative_regulation of Gene_expression of EDN1 17 0.42 7.85 2.71 5.00
57 INT92877 Gene_expression of PDE5A 35 0.76 17.1 2.7 5.00
58 INT127458 Positive_regulation of PAH 24 0.58 27.25 2.53 5.00
59 INT4419 Gene_expression of GOT1 20 0.65 22.53 2.53 5.00
60 INT45167 Positive_regulation of ASAP1 32 0.60 17.09 1.84 5.00
61 INT11948 Negative_regulation of Gene_expression of Vip 9 0.43 2.8 1.54 5.00
62 INT60772 Negative_regulation of Ednrb 8 0.41 4.56 1.39 5.00
63 INT95116 Negative_regulation of PDGFA 24 0.57 19.56 1.29 5.00
64 INT49258 Negative_regulation of Positive_regulation of EDN1 10 0.43 7.24 1.12 5.00
65 INT207421 Positive_regulation of Gene_expression of GPT 9 0.49 5.62 0.83 5.00
66 INT36978 Localization of Pah 9 0.73 7.43 0.82 5.00
67 INT44614 Gene_expression of FCGR2C 7 0.29 5.6 0.68 5.00
68 INT256204 Negative_regulation of ERAS 4 0.31 1.71 0.57 5.00
69 INT79599 Protein_catabolism of PDE5A 7 1.00 3.16 0.39 5.00
70 INT70701 Binding of FCGR3A 5 0.36 1.2 0.38 5.00
71 INT266784 Regulation of ERAS 2 0.28 1.73 0.37 5.00
72 INT121087 Gene_expression of Pde7a 3 0.17 2.69 0.31 5.00
73 INT213214 Positive_regulation of ASAP2 1 0.01 4.59 0.31 5.00
74 INT213215 Gene_expression of SS18L1 2 0.58 3.71 0.29 5.00
75 INT127462 Regulation of PAH 5 0.39 3.35 0.29 5.00
76 INT213219 Protein_catabolism of ALDH7A1 1 0.14 0.7 0.23 5.00
77 INT74132 Positive_regulation of FCGR2C 2 0.13 0.72 0.23 5.00
78 INT213217 Negative_regulation of Binding of PAH 2 0.32 2.03 0.19 5.00
79 INT213222 Negative_regulation of Protein_catabolism of PDE5A 1 0.24 0.65 0.16 5.00
80 INT213218 Negative_regulation of USP33 1 0.01 0.92 0.15 5.00
81 INT230729 Regulation of Gene_expression of Pah 1 0.24 1 0.13 5.00
82 INT213212 Localization of ASAP2 1 0.01 0.78 0.13 5.00
83 INT211827 Localization of PVR 3 0.61 1.33 0.13 5.00
84 INT213211 Regulation of Localization of PVR 1 0.23 0.78 0.13 5.00
85 INT206463 Positive_regulation of Positive_regulation of ASAP1 4 0.41 1.28 0.07 5.00
86 INT230731 Positive_regulation of Negative_regulation of Hbb 1 0.01 0.52 0.07 5.00
87 INT213213 Protein_catabolism of PAH 1 0.76 1.5 0.07 5.00
88 INT213216 Positive_regulation of Gene_expression of PDE5A 2 0.37 2.08 0.04 5.00
89 INT353116 Binding of Pde7a 1 0.08 0.59 0 5.00
90 INT278829 Positive_regulation of Gene_expression of PVR 4 0.40 1.51 0 5.00
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