D:Embryo Loss

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pChart

Disease Term
Synonyms BLASTOCYST DISINTEGRATION, Death Embryo, Disintegration Blastocyst, Disintegration Of Blastocyst, Disintegration Of Embryo, Embryo Death, Embryo Deaths, Embryo Disintegration, Embryo Resorption, RESORPTION EMBRYO
Documents 9
Hot Single Events 26
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Embryo Loss. They are ordered first by their relevance to Embryo Loss and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT338767 Positive_regulation of Binding of Hand1 and Hand2 1 0.07 0.5 0.2 99.64
2 INT338426 Binding of Hand1 and Hand2 2 0.06 2 0.46 99.42
3 INT187668 Negative_regulation of GNRH1 Positive_regulation of PLOD1 1 0.06 0.07 0 65.24
4 INT45780 GNRH1 Positive_regulation of PLOD1 3 0.07 1.02 0.63 64.64
5 INT338765 Regulation of Binding of Cd4 and Tlr4 1 0.09 0.05 0 37.08
6 INT338768 Binding of Cd4 and Tlr4 1 0.08 0.05 0 37.08
7 INT338770 IFN1@ Positive_regulation of Gene_expression of Ifng 1 0.51 0.74 0.04 10.96
8 INT338766 Tlr4 Positive_regulation of Gene_expression of Ifng 1 0.13 0.77 0.04 10.56
9 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89 5.00
10 INT186783 Binding of ESR1 and NRIP1 1 0.31 0.79 0.25 5.00
11 INT186782 Binding of RARB and NRIP1 1 0.03 0.49 0.2 5.00
12 INT186781 Binding of NRIP1 and GOPC 1 0.05 0.49 0.2 5.00
13 INT65676 Binding of CGA and PLOD1 3 0.23 1.68 0.1 5.00
14 INT260944 Mapk14 Positive_regulation of Transcription of Aqp3 1 0.29 0.21 0.09 5.00
15 INT260947 Mapk14 Positive_regulation of Aqp3 1 0.29 0.21 0.09 5.00
16 INT260945 Mapk14 Positive_regulation of Gene_expression of Aqp3 1 0.29 0.21 0.09 5.00
17 INT187671 CGA Negative_regulation of Gene_expression of GNRH1 1 0.01 0 0.06 5.00
18 INT338769 Tlr4 Positive_regulation of Localization of Tnf 1 0.08 0.76 0.04 5.00
19 INT187732 Binding of CYP19A1 and Cyp11a1 1 0.01 0.68 0.04 5.00
20 INT260948 Khsrp Negative_regulation of Binding of Elavl1 1 0.24 0.11 0.03 5.00
21 INT260946 Zfp36 Negative_regulation of Binding of Elavl1 1 0.21 0.11 0.03 5.00
22 INT187676 Binding of CYP19A1 and SHBG 1 0.01 0.63 0.03 5.00
23 INT187672 Binding of DBT and SCN5A 1 0.00 0.2 0 5.00
24 INT187677 Negative_regulation of FSHR Positive_regulation of DBT 1 0.03 0 0 5.00
25 INT187675 DBT Positive_regulation of Gene_expression of LEP 1 0.04 0.27 0 5.00
26 INT187674 FSHR Positive_regulation of Gene_expression of CYP19A1 1 0.24 0 0 5.00
27 INT187667 DBT Positive_regulation of Localization of LEP 1 0.05 0.55 0 5.00
28 INT187669 FSHR Positive_regulation of DBT 1 0.03 0 0 5.00
29 INT187673 GNRH1 Regulation of Localization of PLOD1 1 0.06 0.09 0 5.00
30 INT187670 Gene_expression of FSHR Positive_regulation of Gene_expression of CYP19A1 1 0.16 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Embryo Loss. They are ordered first by their pain relevance and then by number of times they were reported in Embryo Loss. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96 99.64
2 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41 99.24
3 INT152225 Regulation of Positive_regulation of Tlr4 8 0.53 2.5 1.12 99.00
4 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 99.00
5 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49 98.74
6 INT186790 Regulation of NRIP1 4 0.45 6.68 0.64 97.76
7 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54 95.16
8 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 94.20
9 INT18909 Positive_regulation of Cd8a 92 0.60 56.55 7.35 94.20
10 INT50255 Regulation of Cd4 39 0.49 29.73 6.77 94.20
11 INT187819 Regulation of IFN1@ 25 0.60 12.89 3.55 94.20
12 INT167035 Regulation of Cd8a 25 0.41 16.78 1.9 94.20
13 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 93.24
14 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 93.08
15 INT20371 Gene_expression of Cd8a 125 0.60 67.59 8.97 93.08
16 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 92.44
17 INT78057 Localization of Tlr4 140 0.77 67.75 21.72 91.96
18 INT87235 Negative_regulation of Il4 54 0.48 31.51 13.15 91.12
19 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28 91.12
20 INT38556 Gene_expression of DBT 47 0.50 12.52 5.6 86.16
21 INT186784 Positive_regulation of Nrip1 1 0.39 1.1 0.21 84.32
22 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03 84.12
23 INT94465 Positive_regulation of Gene_expression of Hand1 43 0.38 29.76 10.88 82.96
24 INT186786 Positive_regulation of NRIP1 3 0.50 4.81 0.42 82.72
25 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 82.24
26 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 81.04
27 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 79.52
28 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 68.52
29 INT221508 Phosphorylation of IFN1@ 14 0.79 8.97 0.77 68.12
30 INT260903 Regulation of Rbp4 1 0.06 0.27 0 67.56
31 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 67.52
32 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75 60.48
33 INT192409 Positive_regulation of Gene_expression of IFN1@ 102 0.67 64.66 18.8 59.80
34 INT20379 Localization of Il4 85 0.73 51.22 20.55 57.48
35 INT112017 Regulation of Hand2 77 0.36 62.23 18.04 56.32
36 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 56.00
37 INT274482 Regulation of Positive_regulation of IFN1@ 4 0.44 1.44 0.33 51.52
38 INT173505 Localization of Hand2 63 0.57 45.32 13.66 44.72
39 INT20378 Localization of Hand1 53 0.71 41.96 13.31 41.20
40 INT6852 Localization of TNF 883 0.81 705.95 270.84 40.80
41 INT20381 Localization of Il2 71 0.77 34.23 13.03 40.80
42 INT6481 Binding of TNF 624 0.48 510.2 214.82 29.52
43 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31 29.52
44 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 25.92
45 INT217744 Positive_regulation of GNS 4 0.24 1.39 1 24.60
46 INT16102 Negative_regulation of Gene_expression of GNRH1 5 0.39 0.85 0.64 24.36
47 INT5131 Gene_expression of GNRH1 109 0.78 28.79 23.94 24.12
48 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 23.52
49 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 17.68
50 INT920 Localization of PLOD1 223 0.81 42.25 78.7 15.24
51 INT912 Localization of FSHR 91 0.79 23.61 15.58 15.24
52 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6 10.56
53 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
54 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
55 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
56 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47 5.00
57 INT1793 Localization of CGA 379 0.81 67.38 114.69 5.00
58 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
59 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
60 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 5.00
61 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79 5.00
62 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
63 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
64 INT6761 Binding of CALCA 100 0.48 26.71 62.05 5.00
65 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 5.00
66 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
67 INT251 Regulation of INS 398 0.62 232.47 55.04 5.00
68 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32 5.00
69 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 5.00
70 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
71 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
72 INT5130 Regulation of GNRH1 139 0.62 31.95 42.08 5.00
73 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
74 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
75 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 5.00
76 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 5.00
77 INT913 Regulation of Localization of PLOD1 71 0.62 8.64 32.72 5.00
78 INT35406 Localization of Tnf 94 0.81 64.63 31.65 5.00
79 INT7975 Regulation of PLOD1 97 0.62 20.9 30.51 5.00
80 INT7397 Negative_regulation of Localization of GNRH1 86 0.59 15.45 29.78 5.00
81 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76 5.00
82 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
83 INT7035 Regulation of CGA 87 0.45 29.04 28.45 5.00
84 INT5135 Negative_regulation of GNRH1 106 0.58 36.63 27.71 5.00
85 INT1638 Negative_regulation of PLOD1 92 0.59 21.69 26.61 5.00
86 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
87 INT172458 Regulation of Gopc 155 0.53 62.57 24.86 5.00
88 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 5.00
89 INT7113 Negative_regulation of Localization of CGA 71 0.51 17.7 23.42 5.00
90 INT917 Positive_regulation of Localization of PLOD1 51 0.69 8.53 22.87 5.00
91 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52 5.00
92 INT4612 Positive_regulation of Localization of CGA 64 0.64 8.51 22.39 5.00
93 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21 5.00
94 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 5.00
95 INT1644 Regulation of FSHR 77 0.55 15.62 21.49 5.00
96 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
97 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22 5.00
98 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 5.00
99 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 5.00
100 INT1642 Negative_regulation of Localization of PLOD1 40 0.58 10.67 17.95 5.00
101 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 5.00
102 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 5.00
103 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 5.00
104 INT170754 Localization of IFN1@ 121 0.78 66.78 15.6 5.00
105 INT26538 Positive_regulation of FSHR 103 0.69 30.95 15.33 5.00
106 INT75908 Regulation of LEP 77 0.60 60.16 15.19 5.00
107 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 5.00
108 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 5.00
109 INT4145 Gene_expression of FSHR 124 0.77 44.98 13.04 5.00
110 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 5.00
111 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 5.00
112 INT7234 Binding of GNRH1 43 0.47 21.59 12.36 5.00
113 INT117113 Regulation of Mapk14 28 0.45 16.71 11.99 5.00
114 INT116433 Gene_expression of CYBB 93 0.70 50.44 11.91 5.00
115 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17 5.00
116 INT111223 Positive_regulation of HMOX1 47 0.70 39.14 10.92 5.00
117 INT1647 Negative_regulation of FSHR 54 0.45 13.44 8.87 5.00
118 INT75907 Binding of LEP 53 0.46 46.65 8.44 5.00
119 INT119904 Regulation of CYP19A1 25 0.62 9.36 8.34 5.00
120 INT15687 Regulation of ESR1 91 0.60 40.42 7.95 5.00
121 INT8684 Positive_regulation of ANGPTL5 45 0.69 36.29 7.47 5.00
122 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47 5.00
123 INT6906 Negative_regulation of SCN5A 64 0.43 20.64 7.3 5.00
124 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25 5.00
125 INT800 Negative_regulation of Grhpr 21 0.42 10.3 7.17 5.00
126 INT170381 Transcription of Gopc 59 0.60 15.96 6.82 5.00
127 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24 5.00
128 INT146594 Negative_regulation of Gene_expression of LEP 25 0.42 18.88 5.71 5.00
129 INT34592 Positive_regulation of Gene_expression of ALPP 51 0.67 20.62 5.68 5.00
130 INT65356 Localization of LEP 46 0.79 41.17 5.43 5.00
131 INT23010 Positive_regulation of CYP19A1 28 0.58 24.18 5.37 5.00
132 INT23598 Binding of SCN5A 32 0.40 16 5.35 5.00
133 INT30209 Localization of SCN5A 24 0.72 7.95 5.35 5.00
134 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08 5.00
135 INT178754 Positive_regulation of Localization of GOPC 32 0.43 10.1 4.73 5.00
136 INT8773 Gene_expression of HBG1 58 0.76 37.6 4.59 5.00
137 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12 5.00
138 INT63121 Binding of APC 29 0.41 23.02 3.8 5.00
139 INT48499 Transcription of GNRH1 11 0.67 0.74 3.48 5.00
140 INT1646 Negative_regulation of Localization of FSHR 17 0.58 7.36 3.46 5.00
141 INT69438 Negative_regulation of Positive_regulation of ROS1 20 0.48 10.6 3.33 5.00
142 INT57252 Negative_regulation of PGR 22 0.43 12.95 3.33 5.00
143 INT180971 Protein_catabolism of GOPC 21 0.77 6.15 2.98 5.00
144 INT7976 Regulation of Gene_expression of CGA 8 0.19 1.09 2.71 5.00
145 INT101246 Gene_expression of Gata6 6 0.68 3.03 2.68 5.00
146 INT50080 Binding of APOE 38 0.45 29.61 2.67 5.00
147 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51 5.00
148 INT32920 Gene_expression of Msx1 19 0.71 4.24 2.42 5.00
149 INT12033 Binding of PLOD1 15 0.48 8.04 2.3 5.00
150 INT83236 Localization of PGR 14 0.73 8.26 2.23 5.00
151 INT27644 Gene_expression of BRD2 23 0.65 6.97 2.23 5.00
152 INT9254 Negative_regulation of LDHA 23 0.43 13.3 2.2 5.00
153 INT109971 Positive_regulation of Tpt1 23 0.69 13.69 2.14 5.00
154 INT111113 Binding of CYP19A1 15 0.36 9.17 2.12 5.00
155 INT104564 Gene_expression of Aqp3 8 0.65 4.92 1.99 5.00
156 INT7974 Regulation of Gene_expression of PLOD1 6 0.42 0.41 1.99 5.00
157 INT20276 Positive_regulation of Abo 4 0.07 1.04 1.98 5.00
158 INT7972 Positive_regulation of Gene_expression of PLOD1 15 0.42 5.73 1.96 5.00
159 INT33496 Positive_regulation of Gene_expression of FSHR 14 0.46 6.05 1.66 5.00
160 INT149642 Binding of Elavl1 5 0.23 5.49 1.59 5.00
161 INT7033 Binding of FSHR 19 0.37 6.66 1.52 5.00
162 INT1641 Positive_regulation of Negative_regulation of FSHR 3 0.41 1.7 1.43 5.00
163 INT189948 Gene_expression of Pttg1 106 0.76 104.68 1.41 5.00
164 INT260901 Localization of Elavl1 2 0.47 8.78 1.18 5.00
165 INT168135 Localization of H3 10 0.30 4 1.15 5.00
166 INT159543 Localization of SOD1 29 0.75 8.62 1.06 5.00
167 INT172529 Negative_regulation of Gene_expression of PGR 24 0.48 16.69 1.04 5.00
168 INT105543 Gene_expression of DNTT 11 0.65 4.63 1 5.00
169 INT260905 Phosphorylation of Khsrp 2 0.52 2.3 1 5.00
170 INT175280 Binding of DBT 19 0.08 6.37 0.98 5.00
171 INT8772 Positive_regulation of Gene_expression of HBG1 16 0.68 6.93 0.95 5.00
172 INT260921 Negative_regulation of Khsrp 2 0.34 3.12 0.94 5.00
173 INT38557 Positive_regulation of Gene_expression of DBT 8 0.37 2.05 0.92 5.00
174 INT38558 Positive_regulation of DBT 9 0.31 1.59 0.86 5.00
175 INT147488 Gene_expression of Eef1a2 5 0.49 0.87 0.84 5.00
176 INT187709 Regulation of Gene_expression of DBT 3 0.04 0.63 0.8 5.00
177 INT124850 Gene_expression of Tpt1 42 0.77 14.51 0.79 5.00
178 INT181016 Gene_expression of Plac8 4 0.46 5.45 0.72 5.00
179 INT57062 Regulation of APC 24 0.58 14.3 0.7 5.00
180 INT270428 Negative_regulation of Binding of APOE 2 0.41 1.16 0.7 5.00
181 INT180149 Positive_regulation of SRA1 7 0.40 2.65 0.65 5.00
182 INT187712 Negative_regulation of DBT 11 0.19 2.99 0.65 5.00
183 INT185244 Gene_expression of Sox2 27 0.65 4.71 0.61 5.00
184 INT171105 Positive_regulation of Positive_regulation of CYP19A1 5 0.39 4.02 0.58 5.00
185 INT260906 Binding of Khsrp 2 0.30 1.48 0.57 5.00
186 INT187714 Regulation of Negative_regulation of PLOD1 1 0.09 0 0.51 5.00
187 INT187721 Transcription of PLOD1 4 0.49 4.69 0.51 5.00
188 INT71046 Localization of CYP19A1 2 0.78 1.38 0.48 5.00
189 INT187717 Regulation of Negative_regulation of CYP19A1 11 0.42 2.85 0.45 5.00
190 INT127890 Positive_regulation of Negative_regulation of CYP19A1 6 0.50 1.41 0.45 5.00
191 INT187726 Positive_regulation of Localization of LEP 5 0.50 5.31 0.41 5.00
192 INT260917 Positive_regulation of Localization of Elavl1 2 0.32 4.1 0.41 5.00
193 INT245308 Gene_expression of NDUFAB1 11 0.11 4.57 0.39 5.00
194 INT260916 Regulation of Elavl1 2 0.21 2.47 0.38 5.00
195 INT187716 Positive_regulation of Positive_regulation of DBT 2 0.08 0 0.34 5.00
196 INT135772 Regulation of Positive_regulation of HMOX1 3 0.39 1.52 0.29 5.00
197 INT190451 Gene_expression of NANOG 33 0.59 3.28 0.29 5.00
198 INT260922 Gene_expression of Alox15 2 0.32 0.58 0.27 5.00
199 INT164210 Gene_expression of Cdx2 3 0.56 2.22 0.25 5.00
200 INT260918 Regulation of Khsrp 2 0.28 1.33 0.25 5.00
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