D:Empyema

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pChart

Disease Term
Synonyms None
Documents 339
Hot Single Events 16
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Empyema. They are ordered first by their relevance to Empyema and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT323623 Binding of Adm and Edn1 1 0.04 0.77 0.03 19.20
2 INT252646 Binding of C6orf25 and SYT16 1 0.00 0.51 0.17 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Empyema. They are ordered first by their pain relevance and then by number of times they were reported in Empyema. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT165922 Positive_regulation of Scl19 1 0.43 2.25 0.27 99.88
2 INT40007 Regulation of DNASE1 4 0.44 2.98 0.53 99.48
3 INT49233 Regulation of Localization of DNASE1 2 0.44 0.99 0.27 99.48
4 INT252662 Binding of SYT16 1 0.01 8.05 0.45 99.44
5 INT103655 Positive_regulation of TBC1D1 1 0.40 2.1 0.08 98.70
6 INT209355 Binding of SLC9A6 8 0.42 14.9 0.09 98.52
7 INT49235 Localization of DNASE1 7 0.81 1.69 1.04 98.00
8 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 94.42
9 INT237842 Negative_regulation of TPCN1 3 0.06 0.86 0.09 92.56
10 INT58160 Positive_regulation of TRIM27 1 0.45 0.98 0.09 92.52
11 INT16214 Localization of F13A1 36 0.74 21.8 4.87 89.72
12 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 86.40
13 INT209354 Gene_expression of SLC9A6 15 0.58 37.52 0.29 85.92
14 INT4047 Binding of F13A1 105 0.43 66.54 11.81 85.52
15 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 85.04
16 INT68216 Binding of NF1 40 0.48 51.24 4.59 81.56
17 INT108798 Negative_regulation of Positive_regulation of ALPP 9 0.25 4.26 1.46 76.92
18 INT23105 Gene_expression of MS4A1 5 0.75 5.17 0.95 75.00
19 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 75.00
20 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 75.00
21 INT36263 Positive_regulation of CEL 53 0.69 34.88 12.87 75.00
22 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 74.52
23 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 74.16
24 INT4422 Positive_regulation of Gene_expression of Alb 30 0.50 18.56 6.12 74.16
25 INT129227 Binding of DNASE1 4 0.14 2.54 0.54 73.72
26 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 73.48
27 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 72.68
28 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 69.28
29 INT263636 Binding of FAM83H 1 0.01 0.27 0 68.32
30 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 65.04
31 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 65.04
32 INT36689 Gene_expression of Bpifa2 27 0.50 14.92 1.65 64.64
33 INT122557 Localization of Chdh 6 0.74 4.44 2.6 63.56
34 INT52905 Gene_expression of Cd4 84 0.78 45.68 12.75 62.48
35 INT342587 Regulation of Binding of LDHA 1 0.44 1.12 0.04 62.48
36 INT24815 Binding of LDHA 9 0.36 6.73 0.89 60.04
37 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 59.48
38 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79 59.48
39 INT37480 Binding of BTS1 2 0.36 0.8 0.19 55.60
40 INT59900 Binding of MATN3 13 0.42 17.19 3.59 54.68
41 INT4535 Localization of PROC 106 0.73 76.24 21.1 51.32
42 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 50.60
43 INT72798 Binding of ADA 12 0.47 7.84 3.39 50.60
44 INT122653 Positive_regulation of Gene_expression of CD4 48 0.68 22.5 5.96 50.08
45 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 50.00
46 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 49.92
47 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 48.88
48 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5 48.88
49 INT263637 Gene_expression of FAM83H 1 0.01 0 0 39.68
50 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 32.68
51 INT109081 Localization of Nppa 9 0.59 2.72 0.61 29.80
52 INT6361 Localization of Edn1 30 0.81 19.09 9.7 29.40
53 INT118987 Localization of Adm 4 0.50 0.34 0.84 29.40
54 INT228976 Binding of MCAT 3 0.06 3.45 0.17 25.72
55 INT58477 Gene_expression of Chdh 33 0.74 39.48 19.78 25.00
56 INT1168 Binding of PROC 62 0.38 44.15 9.04 24.92
57 INT53374 Binding of Edn1 17 0.43 11.66 2.98 19.20
58 INT323621 Binding of Adm 1 0.32 1.02 0.03 19.20
59 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 16.44
60 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 5.00
61 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
62 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
63 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
64 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
65 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
66 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
67 INT10166 Localization of Tnf 237 0.81 153.95 88.64 5.00
68 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 5.00
69 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
70 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
71 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 5.00
72 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 5.00
73 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 5.00
74 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
75 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
76 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43 5.00
77 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75 5.00
78 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 5.00
79 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 5.00
80 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23 5.00
81 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
82 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46 5.00
83 INT2630 Positive_regulation of Shbg 134 0.70 65.26 15.19 5.00
84 INT59870 Gene_expression of F3 51 0.65 51.83 14.01 5.00
85 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 5.00
86 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8 5.00
87 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 5.00
88 INT3602 Negative_regulation of Shbg 148 0.53 69.05 11.65 5.00
89 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35 5.00
90 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51 5.00
91 INT22798 Regulation of Shbg 64 0.60 26.71 8.76 5.00
92 INT93310 Gene_expression of CAP1 14 0.58 3.07 8.55 5.00
93 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18 5.00
94 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9 5.00
95 INT52180 Binding of Aes 38 0.42 23.16 6.7 5.00
96 INT55034 Positive_regulation of Adm 27 0.61 14.1 6.13 5.00
97 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56 5.00
98 INT78393 Gene_expression of Adm 16 0.78 8.4 4.92 5.00
99 INT4649 Positive_regulation of Chrna7 17 0.50 5.48 3.92 5.00
100 INT149259 Gene_expression of RCT 38 0.67 15.73 3.87 5.00
101 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6 5.00
102 INT19211 Binding of Shbg 35 0.48 16.29 3.31 5.00
103 INT78467 Negative_regulation of IL12A 18 0.38 11.29 2.98 5.00
104 INT177586 Positive_regulation of Gene_expression of MRI1 9 0.33 4.97 2.91 5.00
105 INT76875 Positive_regulation of Adm 12 0.58 3.36 2.72 5.00
106 INT16461 Negative_regulation of Gene_expression of PROC 13 0.24 4.39 2.17 5.00
107 INT135961 Positive_regulation of Hc 8 0.67 3.67 1.87 5.00
108 INT88934 Regulation of SPP1 9 0.54 6.94 1.47 5.00
109 INT73432 Gene_expression of Nppa 32 0.59 21.04 1.39 5.00
110 INT127283 Regulation of Gene_expression of HMOX1 14 0.61 11.8 1.28 5.00
111 INT2270 Positive_regulation of Gene_expression of F2 6 0.21 4.23 1.26 5.00
112 INT91122 Localization of CAT 6 0.78 4.13 1.19 5.00
113 INT44817 Negative_regulation of Gene_expression of Shbg 9 0.34 9.84 1.11 5.00
114 INT160576 Gene_expression of Psgb1 3 0.35 1.63 1.08 5.00
115 INT4436 Gene_expression of ABCB7 7 0.65 9.26 0.93 5.00
116 INT2482 Regulation of Positive_regulation of REN 4 0.59 2.62 0.91 5.00
117 INT251026 Negative_regulation of Phosphorylation of CDKN2A 5 0.42 5.02 0.62 5.00
118 INT174271 Binding of F3 6 0.15 6.85 0.53 5.00
119 INT176646 Binding of Bpifa2 15 0.30 7.65 0.5 5.00
120 INT178812 Binding of ARC 6 0.36 10.75 0.47 5.00
121 INT252658 Negative_regulation of Phosphorylation of ABCB7 1 0.41 2.93 0.45 5.00
122 INT252657 Positive_regulation of Phosphorylation of CDKN2A 2 0.45 3.09 0.42 5.00
123 INT153705 Gene_expression of CLDN3 5 0.58 4.07 0.37 5.00
124 INT228977 Binding of SERPINA2 1 0.25 5.42 0.35 5.00
125 INT263635 Negative_regulation of NAGK 1 0.35 0.35 0.33 5.00
126 INT251025 Phosphorylation of CDKN2A 4 0.61 3.19 0.32 5.00
127 INT174272 Negative_regulation of Gene_expression of F3 5 0.14 4.06 0.31 5.00
128 INT252661 Positive_regulation of Gene_expression of ABCB7 2 0.49 1.55 0.31 5.00
129 INT252660 Positive_regulation of Phosphorylation of ABCB7 1 0.49 1.94 0.3 5.00
130 INT252656 Positive_regulation of Binding of F3 1 0.07 1.89 0.29 5.00
131 INT326515 Negative_regulation of JAZF1 1 0.03 0 0.22 5.00
132 INT263634 Gene_expression of NAGK 1 0.46 0.17 0.21 5.00
133 INT319739 Negative_regulation of Psgb1 1 0.22 0.29 0.17 5.00
134 INT252659 Phosphorylation of ABCB7 1 0.79 0.97 0.15 5.00
135 INT209356 Regulation of SLC9A6 2 0.39 5.61 0.14 5.00
136 INT263638 Localization of PLA1A 1 0.01 0.22 0.09 5.00
137 INT280499 Regulation of SUPV3L1 1 0.01 1.6 0.09 5.00
138 INT263633 Gene_expression of PLA1A 1 0.01 0.2 0.09 5.00
139 INT193439 Localization of MCO 1 0.61 0.49 0.08 5.00
140 INT193438 Binding of MCO 1 0.39 1.77 0.06 5.00
141 INT280498 Positive_regulation of SUPV3L1 1 0.01 2.73 0.04 5.00
142 INT193440 Positive_regulation of MCO 4 0.45 1.22 0 5.00
143 INT323622 Gene_expression of Amh 1 0.01 1.91 0 5.00
144 INT193437 Negative_regulation of MCO 4 0.48 0.68 0 5.00
145 INT228975 Gene_expression of SERPINA2 1 0.31 1.61 0 5.00
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