D:Encephalocele

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Disease Term
Synonyms ACQUIRED ENCEPHALOCELE, Acquired Encephaloceles, CEREBRAL HERNIA, Cerebral Hernias, Encephalocele Acquired, Encephalocele Frontal, Encephalocele Occipital, Encephalocele Sincipital, Encephaloceles, Encephaloceles Acquired, Encephaloceles Frontal
Documents 43
Hot Single Events 3
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Encephalocele. They are ordered first by their relevance to Encephalocele and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69 5.00
2 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37 5.00
3 INT265886 IGF1 Positive_regulation of AKT1 1 0.11 3.06 0.23 5.00
4 INT265892 IGF1 Positive_regulation of PIK3CG 1 0.18 1.96 0.16 5.00
5 INT265888 BCL2 Regulation of Gene_expression of BAD 1 0.04 1.08 0.1 5.00
6 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1 5.00
7 INT265889 BAX Regulation of Gene_expression of BAD 1 0.06 1.08 0.1 5.00
8 INT265887 IGF1 Negative_regulation of BCL2 1 0.09 1.02 0.09 5.00
9 INT239643 Binding of BCL2 and BCL2L11 3 0.16 2.26 0.09 5.00
10 INT265878 IGF1 Negative_regulation of Binding of BCL2 and BCL2L11 1 0.03 1.03 0.09 5.00
11 INT265883 IGF1 Positive_regulation of Transcription of FOXO1 1 0.17 1.14 0.07 5.00
12 INT265882 IGF1 Positive_regulation of Transcription of AKT1 1 0.08 1.13 0.07 5.00
13 INT265877 IGF1 Regulation of Binding of GH1 and IGF1 1 0.03 0.47 0.07 5.00
14 INT265893 BAD Regulation of FOXO1 1 0.03 1.08 0.06 5.00
15 INT241536 Binding of Abcb1b and Abcg2 1 0.10 0.17 0.04 5.00
16 INT265891 IGF1 Regulation of AKT1 1 0.05 1.24 0.03 5.00
17 INT265884 IGF1 Regulation of CREB1 1 0.13 1.31 0.03 5.00
18 INT265879 IGF1 Regulation of FOXO1 1 0.11 1.37 0.03 5.00
19 INT265880 IGF1 Regulation of PIK3CG 1 0.10 1.23 0.03 5.00
20 INT265881 GHRH Positive_regulation of GHR 1 0.05 0.05 0.03 5.00
21 INT265906 IGF1 Regulation of Gsk3b 1 0.25 1.31 0.03 5.00
22 INT241535 Abl1 Regulation of Positive_regulation of Jak2 1 0.10 0.53 0 5.00
23 INT241537 Negative_regulation of Binding of Abl1 and Src 1 0.04 0.14 0 5.00
24 INT241539 Binding of Abl1 and Lyn 1 0.09 0.14 0 5.00
25 INT241534 Binding of Abl1 and Src 1 0.04 0.14 0 5.00
26 INT241538 Negative_regulation of Binding of Abl1 and Lyn 1 0.11 0.14 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Encephalocele. They are ordered first by their pain relevance and then by number of times they were reported in Encephalocele. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 89.36
2 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 85.68
3 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 85.68
4 INT952 Negative_regulation of GHRH 57 0.56 25.3 10.34 74.92
5 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 72.84
6 INT10694 Binding of Bche 19 0.48 8.03 4.85 70.48
7 INT9677 Negative_regulation of Gene_expression of GH1 46 0.48 23.32 3.68 64.12
8 INT9683 Binding of GH1 57 0.47 21.14 5.99 46.16
9 INT745 Gene_expression of Afp 65 0.78 52.89 4.24 41.36
10 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 40.64
11 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 35.44
12 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 33.80
13 INT34741 Positive_regulation of Gene_expression of GH1 58 0.67 35.06 7.8 21.04
14 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26 13.28
15 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
16 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
17 INT252 Localization of GH1 529 0.80 227.4 122.05 5.00
18 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
19 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
20 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
21 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
22 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91 5.00
23 INT9489 Gene_expression of SFTPA1 112 0.66 55.38 66.45 5.00
24 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 5.00
25 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
26 INT6623 Gene_expression of NA 231 0.78 45.78 59.36 5.00
27 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 5.00
28 INT249 Localization of GHRH 215 0.80 78.02 51.87 5.00
29 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 5.00
30 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
31 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
32 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 5.00
33 INT4449 Positive_regulation of NA 179 0.55 40.26 37.82 5.00
34 INT255 Regulation of Localization of GH1 89 0.62 18.71 35.3 5.00
35 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 5.00
36 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 5.00
37 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 5.00
38 INT11014 Phosphorylation of CREB1 72 0.81 26.35 25.64 5.00
39 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 5.00
40 INT8836 Positive_regulation of SFTPA1 36 0.47 28.37 23.59 5.00
41 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7 5.00
42 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 5.00
43 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15 5.00
44 INT23257 Regulation of CRP 127 0.62 100.05 21.87 5.00
45 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95 5.00
46 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94 5.00
47 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 5.00
48 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 5.00
49 INT6791 Binding of NA 55 0.46 5.36 17.59 5.00
50 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 5.00
51 INT59929 Negative_regulation of CYP2C9 60 0.59 16.33 15.39 5.00
52 INT106745 Localization of CRP 65 0.81 66.44 15.21 5.00
53 INT34952 Regulation of ABAT 28 0.61 6.05 14.39 5.00
54 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82 5.00
55 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48 5.00
56 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34 5.00
57 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 5.00
58 INT48335 Negative_regulation of NOSTRIN 38 0.56 16.22 12.05 5.00
59 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64 5.00
60 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 5.00
61 INT54588 Positive_regulation of CREB1 38 0.67 12.01 9.18 5.00
62 INT51530 Negative_regulation of Adk 11 0.56 3.83 9.07 5.00
63 INT25381 Localization of Csf2 62 0.76 47.48 9.03 5.00
64 INT138889 Positive_regulation of Slc12a2 23 0.65 18.53 8.85 5.00
65 INT34777 Localization of IGF1 82 0.80 42.68 8.62 5.00
66 INT113987 Localization of IK 29 0.23 16.73 8.25 5.00
67 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92 5.00
68 INT24978 Binding of SFTPA1 22 0.47 15.09 7.76 5.00
69 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 5.00
70 INT24891 Gene_expression of SYP 55 0.75 45.76 7.53 5.00
71 INT115213 Regulation of SFTPA1 13 0.32 6.91 7.11 5.00
72 INT79062 Gene_expression of B4GALNT1 42 0.14 18.89 6.98 5.00
73 INT105287 Positive_regulation of Slco1c1 24 0.34 15.41 6.81 5.00
74 INT84685 Regulation of BCL2 67 0.60 72.96 6.65 5.00
75 INT92447 Negative_regulation of Gene_expression of SFTPA1 6 0.35 2.81 5.43 5.00
76 INT186063 Phosphorylation of SOAT1 29 0.28 11.77 5.34 5.00
77 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19 5.00
78 INT3275 Negative_regulation of Slco1c1 28 0.37 10.93 5.15 5.00
79 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86 5.00
80 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75 5.00
81 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61 5.00
82 INT130295 Gene_expression of Abcg2 21 0.75 9.75 3.42 5.00
83 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09 5.00
84 INT16130 Binding of IGF1 67 0.48 27.43 2.95 5.00
85 INT14448 Localization of COL5A2 34 0.67 17.35 2.85 5.00
86 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57 5.00
87 INT11787 Positive_regulation of Positive_regulation of NA 14 0.21 2.97 2.46 5.00
88 INT122709 Localization of CYP3A4 16 0.75 5.41 2.38 5.00
89 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37 5.00
90 INT3182 Negative_regulation of PPY 12 0.42 4.65 2.28 5.00
91 INT151449 Negative_regulation of Gene_expression of Kit 18 0.45 12.05 2.23 5.00
92 INT99572 Localization of Kit 13 0.75 5.23 1.95 5.00
93 INT78960 Binding of SOAT1 9 0.36 2.56 1.92 5.00
94 INT164425 Regulation of Gene_expression of SFTPA1 5 0.44 2.46 1.9 5.00
95 INT122500 Protein_catabolism of Slco1c1 17 0.52 16.7 1.7 5.00
96 INT146943 Gene_expression of Src 13 0.49 6.65 1.65 5.00
97 INT25384 Positive_regulation of Localization of Csf2 11 0.66 7.81 1.62 5.00
98 INT113340 Phosphorylation of JAK2 17 0.78 5.69 1.6 5.00
99 INT119835 Positive_regulation of Gene_expression of BAD 6 0.44 7.66 1.51 5.00
100 INT28300 Gene_expression of GHR 10 0.78 4.29 1.5 5.00
101 INT192762 Localization of SAA1 10 0.78 12.63 1.44 5.00
102 INT100540 Localization of SOAT1 9 0.78 2.67 1.42 5.00
103 INT43264 Transcription of GHRH 5 0.59 0.4 1.42 5.00
104 INT119830 Gene_expression of BAD 24 0.50 20.05 1.41 5.00
105 INT124407 Gene_expression of SSTR1 4 0.55 5.55 1.41 5.00
106 INT164325 Negative_regulation of Abcg2 6 0.39 1.88 1.2 5.00
107 INT51264 Positive_regulation of TXK 21 0.54 10.69 1.1 5.00
108 INT32474 Gene_expression of EIF3K 8 0.12 1.64 1 5.00
109 INT164324 Negative_regulation of Gene_expression of Abcg2 4 0.45 1.03 0.99 5.00
110 INT199563 Negative_regulation of Abl1 38 0.46 21.5 0.87 5.00
111 INT241499 Binding of Abl1 23 0.47 8.86 0.75 5.00
112 INT199573 Gene_expression of Abl1 33 0.65 20.79 0.75 5.00
113 INT171364 Localization of Pdgfrb 6 0.37 4.98 0.68 5.00
114 INT79710 Negative_regulation of M1 5 0.32 0.25 0.67 5.00
115 INT79711 Binding of M1 11 0.27 3.77 0.58 5.00
116 INT159864 Localization of CYP3A5 2 0.73 0.33 0.52 5.00
117 INT149999 Negative_regulation of Gene_expression of BAD 4 0.13 5.46 0.45 5.00
118 INT213789 Phosphorylation of Kit 7 0.69 5.32 0.43 5.00
119 INT76690 Negative_regulation of Gene_expression of Vim 1 0.39 1.4 0.42 5.00
120 INT70884 Localization of Pdgfb 8 0.35 6.22 0.42 5.00
121 INT173582 Negative_regulation of Localization of COL5A2 6 0.05 3.24 0.41 5.00
122 INT265898 Transcription of FOXO1 2 0.50 2.29 0.41 5.00
123 INT144021 Binding of Pdgfrb 9 0.37 5.53 0.28 5.00
124 INT265901 Regulation of Localization of CRP 1 0.30 2 0.27 5.00
125 INT265902 Phosphorylation of FOXO1 2 0.59 1.47 0.24 5.00
126 INT241498 Regulation of Abl1 8 0.32 6.46 0.22 5.00
127 INT265899 Regulation of Binding of IGF1 2 0.22 0.94 0.22 5.00
128 INT265903 Gene_expression of FOXO1 3 0.48 2.66 0.2 5.00
129 INT200666 Transcription of AKT1 8 0.66 4.23 0.2 5.00
130 INT199561 Positive_regulation of Gene_expression of Abl1 8 0.36 4.77 0.16 5.00
131 INT200802 Regulation of Jak2 5 0.61 2.86 0.16 5.00
132 INT265904 Localization of FOXO1 3 0.25 2.28 0.15 5.00
133 INT145147 Negative_regulation of Gene_expression of TP63 4 0.42 2.91 0.15 5.00
134 INT265905 Regulation of Localization of SAA1 1 0.60 1 0.14 5.00
135 INT182694 Regulation of Gene_expression of Vim 2 0.24 1.01 0.12 5.00
136 INT241504 Negative_regulation of Aurka 2 0.09 1.54 0.11 5.00
137 INT241512 Phosphorylation of Abl1 4 0.59 2.68 0.09 5.00
138 INT241515 Negative_regulation of Phosphorylation of Abl1 3 0.30 1.36 0.09 5.00
139 INT175415 Negative_regulation of COX10 5 0.07 3.33 0.08 5.00
140 INT194131 Positive_regulation of Binding of SFTPA1 1 0.37 0.23 0.08 5.00
141 INT265900 Positive_regulation of Gene_expression of FOXO1 1 0.19 1.1 0.06 5.00
142 INT241509 Negative_regulation of Gene_expression of Lyn 2 0.20 1.02 0.05 5.00
143 INT241507 Positive_regulation of Abl1 5 0.40 2.69 0.05 5.00
144 INT241506 Localization of Abl1 2 0.54 2.37 0.04 5.00
145 INT241510 Negative_regulation of Phosphorylation of Kit 3 0.31 2.06 0.03 5.00
146 INT225256 Positive_regulation of Gene_expression of Src 3 0.20 0.75 0 5.00
147 INT214045 Negative_regulation of OGG1 5 0.36 3.49 0 5.00
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