D:Enchondromatosis

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pChart

Disease Term
Synonyms Disease Ollier, Disease Ollier S, ENCHONDROMA MULTIPLE, Enchondromas Multiple, Enchondromatoses, ENCHONDROSES MULTIPLE, Enchondrosis Multiple, Maffucci Syndrome, Multiple Enchondroma, Multiple Enchondromas, MULTIPLE ENCHONDROSES
Documents 25
Hot Single Events 11
Hot Interactions 3

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Enchondromatosis. They are ordered first by their relevance to Enchondromatosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT197794 Negative_regulation of Pthlh Regulation of Ihh 1 0.36 1.33 0 99.60
2 INT197793 Pthlh Regulation of Ihh 1 0.22 1.32 0 99.60
3 INT150351 Binding of EXT1 and MMP12 1 0.04 3.68 0.29 86.48
4 INT301364 Stat1 Positive_regulation of Cdkn1a 1 0.03 0.39 0 5.00
5 INT301365 Stat1 Positive_regulation of Cdkn1a 1 0.03 0.38 0 5.00
6 INT301366 Fgf18 Positive_regulation of Fgfr3 1 0.04 0.34 0 5.00
7 INT324053 Binding of Banf1 and Lemd3 1 0.20 0.15 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Enchondromatosis. They are ordered first by their pain relevance and then by number of times they were reported in Enchondromatosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT160622 Gene_expression of Pth1r 7 0.77 6.37 2 97.56
2 INT197790 Gene_expression of Tmem150c 1 0.01 1.06 0 97.56
3 INT197789 Regulation of Gene_expression of Pth1r 2 0.23 1.68 1.38 95.80
4 INT114295 Gene_expression of Gli2 10 0.54 7.58 2.95 94.88
5 INT177347 Positive_regulation of Gene_expression of Gli2 3 0.25 2.61 0.69 94.88
6 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 90.96
7 INT197792 Regulation of Pthlh 3 0.24 2.47 0.18 89.60
8 INT72138 Gene_expression of Pthlh 18 0.75 17.68 1.49 87.28
9 INT140984 Regulation of Ihh 5 0.54 2.81 0.56 87.00
10 INT153257 Regulation of Ptch1 6 0.36 5.92 0.67 86.80
11 INT197791 Regulation of Pth1r 2 0.27 1.31 1.99 86.80
12 INT324046 Gene_expression of Lemd3 1 0.67 1.69 0.1 74.60
13 INT301360 Gene_expression of Ext1 3 0.68 1.01 0 74.60
14 INT243057 Positive_regulation of Fgfr3 1 0.46 0.79 0 50.00
15 INT243058 Positive_regulation of Positive_regulation of Fgfr3 1 0.46 0.8 0 50.00
16 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 5.00
17 INT92680 Gene_expression of Fgf2 59 0.77 28.11 8.12 5.00
18 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86 5.00
19 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25 5.00
20 INT163756 Phosphorylation of Stat1 45 0.82 14.51 6.11 5.00
21 INT112883 Gene_expression of Hspg2 22 0.65 6.54 4.95 5.00
22 INT62268 Positive_regulation of Cdkn1a 33 0.67 14.12 3.26 5.00
23 INT140858 Negative_regulation of SUGT1 9 0.05 8.41 1.4 5.00
24 INT140983 Gene_expression of Ihh 7 0.78 2.06 1.15 5.00
25 INT124850 Gene_expression of Tpt1 42 0.77 14.51 0.79 5.00
26 INT187087 Binding of Cd44 5 0.47 2.79 0.66 5.00
27 INT150949 Gene_expression of Fgfr1 6 0.63 5.71 0.57 5.00
28 INT235835 Negative_regulation of Gene_expression of Hspg2 3 0.15 1.26 0.52 5.00
29 INT232362 Gene_expression of Mgmt 10 0.76 8.08 0.41 5.00
30 INT117440 Positive_regulation of Cdkn1a 3 0.67 2.95 0.4 5.00
31 INT131018 Phosphorylation of Cdkn1a 3 0.61 2.06 0.4 5.00
32 INT166716 Negative_regulation of Ihh 3 0.43 0.67 0.33 5.00
33 INT189833 Negative_regulation of Phosphorylation of Stat1 4 0.51 1.1 0.3 5.00
34 INT232363 Positive_regulation of Gene_expression of Mgmt 8 0.49 6.01 0.28 5.00
35 INT233294 Positive_regulation of Mgmt 2 0.49 4.07 0.21 5.00
36 INT233296 Negative_regulation of Mgmt 3 0.57 1.9 0.19 5.00
37 INT233295 Regulation of Mgmt 2 0.26 1.36 0.15 5.00
38 INT147079 Gene_expression of Ext2 2 0.66 1.04 0.1 5.00
39 INT301361 Phosphorylation of Cdkn1a 2 0.79 1.21 0.09 5.00
40 INT210805 Negative_regulation of IHH 2 0.42 0.74 0.08 5.00
41 INT152777 Phosphorylation of Mgmt 3 0.79 0.6 0.03 5.00
42 INT210587 Binding of Pthlh 1 0.18 1.17 0.03 5.00
43 INT301355 Binding of Ext1 2 0.37 4.07 0.03 5.00
44 INT320085 Positive_regulation of Positive_regulation of Mgmt 1 0.09 0.49 0.03 5.00
45 INT167842 Positive_regulation of EXT1 5 0.50 2.88 0 5.00
46 INT172965 Negative_regulation of Positive_regulation of Cdkn1a 4 0.41 1.84 0 5.00
47 INT228612 Positive_regulation of Gene_expression of EXT1 2 0.50 1.48 0 5.00
48 INT228613 Negative_regulation of Gene_expression of EXT1 1 0.42 1.08 0 5.00
49 INT228614 Negative_regulation of EXT1 1 0.58 0.86 0 5.00
50 INT228615 Gene_expression of EXT2 1 0.66 1.55 0 5.00
51 INT228616 Negative_regulation of Gene_expression of EXT2 1 0.49 0.78 0 5.00
52 INT228617 Transcription of EXT2 1 0.69 1.56 0 5.00
53 INT228618 Gene_expression of EXT1 4 0.77 3.7 0 5.00
54 INT228619 Positive_regulation of EXT2 1 0.49 0.78 0 5.00
55 INT228620 Transcription of EXT1 3 0.71 2.67 0 5.00
56 INT228621 Positive_regulation of Gene_expression of EXT2 1 0.49 0.78 0 5.00
57 INT228622 Positive_regulation of Transcription of EXT1 1 0.46 0.78 0 5.00
58 INT301354 Transcription of Ext1 1 0.46 1 0 5.00
59 INT301356 Binding of Ihh 1 0.08 0.06 0 5.00
60 INT301357 Negative_regulation of Positive_regulation of Fgfr3 1 0.16 0.35 0 5.00
61 INT301358 Negative_regulation of Ext1 2 0.42 1.09 0 5.00
62 INT301359 Positive_regulation of Fgfr3 1 0.19 0.64 0 5.00
63 INT301362 Negative_regulation of Positive_regulation of Cdkn1a 1 0.41 0.39 0 5.00
64 INT324041 Localization of Mro 1 0.33 1.48 0 5.00
65 INT324042 Regulation of Gene_expression of Ext1 1 0.45 0.12 0 5.00
66 INT324043 Localization of Lemd3 1 0.75 0 0 5.00
67 INT324044 Negative_regulation of Lemd3 1 0.43 2.86 0 5.00
68 INT324047 Binding of Lemd3 1 0.48 3.18 0 5.00
69 INT324048 Positive_regulation of Negative_regulation of Lemd3 1 0.50 0.2 0 5.00
70 INT324052 Binding of Banf1 1 0.18 0.48 0 5.00
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