D:Enchondromatosis

Disease Term Synonyms Disease Ollier, Disease Ollier S, ENCHONDROMA MULTIPLE, Enchondromas Multiple, Enchondromatoses, ENCHONDROSES MULTIPLE, Enchondrosis Multiple, Maffucci Syndrome, Multiple Enchondroma, Multiple Enchondromas, MULTIPLE ENCHONDROSES Documents 25 Hot Single Events 11 Hot Interactions 3

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Enchondromatosis. They are ordered first by their relevance to Enchondromatosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT197794	Negative_regulation of Pthlh Regulation of Ihh	1	0.36	1.33	0	99.60
2	INT197793	Pthlh Regulation of Ihh	1	0.22	1.32	0	99.60
3	INT150351	Binding of EXT1 and MMP12	1	0.04	3.68	0.29	86.48
4	INT301364	Stat1 Positive_regulation of Cdkn1a	1	0.03	0.39	0	5.00
5	INT301365	Stat1 Positive_regulation of Cdkn1a	1	0.03	0.38	0	5.00
6	INT301366	Fgf18 Positive_regulation of Fgfr3	1	0.04	0.34	0	5.00
7	INT324053	Binding of Banf1 and Lemd3	1	0.20	0.15	0	5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Enchondromatosis. They are ordered first by their pain relevance and then by number of times they were reported in Enchondromatosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT160622	Gene_expression of Pth1r	7	0.77	6.37	2	97.56
2	INT197790	Gene_expression of Tmem150c	1	0.01	1.06	0	97.56
3	INT197789	Regulation of Gene_expression of Pth1r	2	0.23	1.68	1.38	95.80
4	INT114295	Gene_expression of Gli2	10	0.54	7.58	2.95	94.88
5	INT177347	Positive_regulation of Gene_expression of Gli2	3	0.25	2.61	0.69	94.88
6	INT77307	Gene_expression of Bcl2	399	0.77	319.77	38	90.96
7	INT197792	Regulation of Pthlh	3	0.24	2.47	0.18	89.60
8	INT72138	Gene_expression of Pthlh	18	0.75	17.68	1.49	87.28
9	INT140984	Regulation of Ihh	5	0.54	2.81	0.56	87.00
10	INT153257	Regulation of Ptch1	6	0.36	5.92	0.67	86.80
11	INT197791	Regulation of Pth1r	2	0.27	1.31	1.99	86.80
12	INT324046	Gene_expression of Lemd3	1	0.67	1.69	0.1	74.60
13	INT301360	Gene_expression of Ext1	3	0.68	1.01	0	74.60
14	INT243057	Positive_regulation of Fgfr3	1	0.46	0.79	0	50.00
15	INT243058	Positive_regulation of Positive_regulation of Fgfr3	1	0.46	0.8	0	50.00
16	INT93361	Gene_expression of Trp53	208	0.78	175.35	16.65	5.00
17	INT92680	Gene_expression of Fgf2	59	0.77	28.11	8.12	5.00
18	INT80220	Positive_regulation of Bcl2	71	0.58	57.73	7.86	5.00
19	INT97055	Positive_regulation of Gene_expression of Trp53	51	0.70	45.7	7.25	5.00
20	INT163756	Phosphorylation of Stat1	45	0.82	14.51	6.11	5.00
21	INT112883	Gene_expression of Hspg2	22	0.65	6.54	4.95	5.00
22	INT62268	Positive_regulation of Cdkn1a	33	0.67	14.12	3.26	5.00
23	INT140858	Negative_regulation of SUGT1	9	0.05	8.41	1.4	5.00
24	INT140983	Gene_expression of Ihh	7	0.78	2.06	1.15	5.00
25	INT124850	Gene_expression of Tpt1	42	0.77	14.51	0.79	5.00
26	INT187087	Binding of Cd44	5	0.47	2.79	0.66	5.00
27	INT150949	Gene_expression of Fgfr1	6	0.63	5.71	0.57	5.00
28	INT235835	Negative_regulation of Gene_expression of Hspg2	3	0.15	1.26	0.52	5.00
29	INT232362	Gene_expression of Mgmt	10	0.76	8.08	0.41	5.00
30	INT117440	Positive_regulation of Cdkn1a	3	0.67	2.95	0.4	5.00
31	INT131018	Phosphorylation of Cdkn1a	3	0.61	2.06	0.4	5.00
32	INT166716	Negative_regulation of Ihh	3	0.43	0.67	0.33	5.00
33	INT189833	Negative_regulation of Phosphorylation of Stat1	4	0.51	1.1	0.3	5.00
34	INT232363	Positive_regulation of Gene_expression of Mgmt	8	0.49	6.01	0.28	5.00
35	INT233294	Positive_regulation of Mgmt	2	0.49	4.07	0.21	5.00
36	INT233296	Negative_regulation of Mgmt	3	0.57	1.9	0.19	5.00
37	INT233295	Regulation of Mgmt	2	0.26	1.36	0.15	5.00
38	INT147079	Gene_expression of Ext2	2	0.66	1.04	0.1	5.00
39	INT301361	Phosphorylation of Cdkn1a	2	0.79	1.21	0.09	5.00
40	INT210805	Negative_regulation of IHH	2	0.42	0.74	0.08	5.00
41	INT152777	Phosphorylation of Mgmt	3	0.79	0.6	0.03	5.00
42	INT210587	Binding of Pthlh	1	0.18	1.17	0.03	5.00
43	INT301355	Binding of Ext1	2	0.37	4.07	0.03	5.00
44	INT320085	Positive_regulation of Positive_regulation of Mgmt	1	0.09	0.49	0.03	5.00
45	INT167842	Positive_regulation of EXT1	5	0.50	2.88	0	5.00
46	INT172965	Negative_regulation of Positive_regulation of Cdkn1a	4	0.41	1.84	0	5.00
47	INT228612	Positive_regulation of Gene_expression of EXT1	2	0.50	1.48	0	5.00
48	INT228613	Negative_regulation of Gene_expression of EXT1	1	0.42	1.08	0	5.00
49	INT228614	Negative_regulation of EXT1	1	0.58	0.86	0	5.00
50	INT228615	Gene_expression of EXT2	1	0.66	1.55	0	5.00
51	INT228616	Negative_regulation of Gene_expression of EXT2	1	0.49	0.78	0	5.00
52	INT228617	Transcription of EXT2	1	0.69	1.56	0	5.00
53	INT228618	Gene_expression of EXT1	4	0.77	3.7	0	5.00
54	INT228619	Positive_regulation of EXT2	1	0.49	0.78	0	5.00
55	INT228620	Transcription of EXT1	3	0.71	2.67	0	5.00
56	INT228621	Positive_regulation of Gene_expression of EXT2	1	0.49	0.78	0	5.00
57	INT228622	Positive_regulation of Transcription of EXT1	1	0.46	0.78	0	5.00
58	INT301354	Transcription of Ext1	1	0.46	1	0	5.00
59	INT301356	Binding of Ihh	1	0.08	0.06	0	5.00
60	INT301357	Negative_regulation of Positive_regulation of Fgfr3	1	0.16	0.35	0	5.00
61	INT301358	Negative_regulation of Ext1	2	0.42	1.09	0	5.00
62	INT301359	Positive_regulation of Fgfr3	1	0.19	0.64	0	5.00
63	INT301362	Negative_regulation of Positive_regulation of Cdkn1a	1	0.41	0.39	0	5.00
64	INT324041	Localization of Mro	1	0.33	1.48	0	5.00
65	INT324042	Regulation of Gene_expression of Ext1	1	0.45	0.12	0	5.00
66	INT324043	Localization of Lemd3	1	0.75	0	0	5.00
67	INT324044	Negative_regulation of Lemd3	1	0.43	2.86	0	5.00
68	INT324047	Binding of Lemd3	1	0.48	3.18	0	5.00
69	INT324048	Positive_regulation of Negative_regulation of Lemd3	1	0.50	0.2	0	5.00
70	INT324052	Binding of Banf1	1	0.18	0.48	0	5.00