D:End Stage Liver Disease

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Disease Term
Synonyms Chronic Liver Failure, CHRONIC LIVER FAILURES, FAILURE CHRONIC LIVER, FAILURES CHRONIC LIVER, Liver Failure Chronic, LIVER FAILURES CHRONIC
Documents 57
Hot Single Events 34
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for End Stage Liver Disease. They are ordered first by their relevance to End Stage Liver Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT220289 MARS Regulation of CEBPZ 1 0.02 0.93 0.11 88.92
2 INT251704 Ache Regulation of Gene_expression of Acot1 1 0.08 1.68 0.87 49.52
3 INT251706 Chat Regulation of Gene_expression of Acot1 1 0.06 1.64 0.85 49.52
4 INT251708 Chat Regulation of Acot1 1 0.03 1.64 0.84 49.12
5 INT220288 MARS Regulation of AFM 1 0.06 1.14 0.08 29.56
6 INT339676 CSF2 Positive_regulation of HGF 1 0.08 0.46 0 10.96
7 INT301082 Binding of BCS1L and TARM1 1 0.17 1.21 0 10.36
8 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
9 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
10 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
11 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 5.00
12 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72 5.00
13 INT301083 Binding of BCS1L and MYH7 1 0.36 1.53 0.19 5.00
14 INT350363 Gatm Negative_regulation of NOS1 1 0.00 0.31 0.17 5.00
15 INT293361 Binding of CD80 and KLRD1 1 0.00 0.38 0.16 5.00
16 INT293359 Binding of CD86 and KLRD1 1 0.00 0.38 0.16 5.00
17 INT293312 CTLA4 Negative_regulation of Binding of CD28 and CD80 1 0.01 0.29 0.12 5.00
18 INT227400 Binding of DLAT and HCC 1 0.01 2.82 0.11 5.00
19 INT251712 Fig4 Regulation of Ache 1 0.02 0.23 0.08 5.00
20 INT251710 Fig4 Regulation of Chat 1 0.03 0.23 0.08 5.00
21 INT251705 Fig4 Regulation of Localization of Chat 1 0.05 0.23 0.08 5.00
22 INT251703 Fig4 Regulation of Localization of Ache 1 0.07 0.23 0.08 5.00
23 INT232897 Binding of Rab27a and SAMSN1 1 0.00 0.73 0.08 5.00
24 INT220290 Binding of AFM and MARS 1 0.05 1.09 0.07 5.00
25 INT232902 Binding of YWHAQ and Krt18 1 0.34 0.96 0.07 5.00
26 INT227418 Binding of DLAT and Pdc 1 0.05 1.01 0.07 5.00
27 INT221878 Binding of Ltp and Ctrcts 1 0.00 1.94 0.07 5.00
28 INT232901 Regulation of Binding of YWHAQ and Krt18 1 0.41 0.96 0.07 5.00
29 INT293360 Binding of CSH1 and FKBP1A 1 0.00 0.14 0.05 5.00
30 INT213207 Negative_regulation of ASAP2 Negative_regulation of PVR 1 0.01 0.45 0.04 5.00
31 INT293353 Binding of CD8A and Cd3e 1 0.01 0.07 0.04 5.00
32 INT213206 ASAP2 Negative_regulation of PVR 1 0.01 0.44 0.04 5.00
33 INT251701 Bche Regulation of Gene_expression of Acot1 1 0.03 0.25 0.03 5.00
34 INT293367 Binding of CABIN1 and Ppia 1 0.00 0.19 0.03 5.00
35 INT293358 Binding of FKBP1A and CABIN1 1 0.00 0.07 0.03 5.00
36 INT232900 Binding of ABR and Krt8 1 0.03 0.49 0.03 5.00
37 INT293368 Binding of CSH1 and Ppia 1 0.00 0.19 0.03 5.00
38 INT293355 Binding of Fkbp1a and CABIN1 1 0.00 0.12 0 5.00
39 INT232890 Binding of Rab27a and Gopc 1 0.01 0.3 0 5.00
40 INT232899 Krt18 Negative_regulation of Binding of ABR 1 0.05 0.68 0 5.00
41 INT268809 Binding of IFNA2 and PAEP 1 0.01 0.16 0 5.00
42 INT232893 Binding of ABR and Nup62 1 0.03 0.13 0 5.00
43 INT232895 Krt18 Positive_regulation of Gene_expression of ABR 1 0.46 0.09 0 5.00
44 INT293357 RORC Regulation of PPP2R4 1 0.00 0 0 5.00
45 INT293354 Binding of CSH1 and Fkbp1a 1 0.00 0.12 0 5.00
46 INT318922 XIAP Regulation of COMMD1 1 0.09 0.37 0 5.00
47 INT232898 Binding of KRT1 and Krt8 1 0.27 1.22 0 5.00
48 INT293366 Binding of CABIN1 and Fkbp1a 1 0.00 0.05 0 5.00
49 INT232896 Krt8 Negative_regulation of Binding of ABR 1 0.04 0.68 0 5.00
50 INT339675 CSF2 Positive_regulation of Localization of FUT1 1 0.01 0.42 0 5.00
51 INT293362 CSH1 Negative_regulation of Gene_expression of IL2 1 0.01 0.12 0 5.00
52 INT232892 Krt18 Positive_regulation of Gene_expression of Krt8 1 0.30 0.09 0 5.00
53 INT232889 Binding of Krt18 and Krt8 1 0.22 1.09 0 5.00
54 INT251702 Fig4 Regulation of Positive_regulation of Ache 1 0.07 0.42 0 5.00
55 INT232894 Binding of ABR and Rab27a 1 0.08 0.3 0 5.00
56 INT318919 Binding of ATP7B and COMMD1 1 0.37 0.76 0 5.00
57 INT318920 Binding of XIAP and COMMD1 1 0.12 0.78 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for End Stage Liver Disease. They are ordered first by their pain relevance and then by number of times they were reported in End Stage Liver Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT110208 Binding of ABR 2 0.35 10.49 0.81 99.66
2 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71 99.60
3 INT9155 Gene_expression of Glul 60 0.77 17.97 23.95 99.40
4 INT84964 Gene_expression of MAOB 14 0.61 2.8 0.89 99.40
5 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 99.24
6 INT151526 Regulation of Olfr148 2 0.23 1.93 0.2 98.88
7 INT132667 Regulation of Transcription of NOS1 1 0.30 2.58 0.95 97.40
8 INT48908 Transcription of NOS1 27 0.55 13.46 8.39 96.68
9 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 96.36
10 INT119271 Positive_regulation of BCS1L 13 0.50 7.56 0.39 94.08
11 INT151527 Positive_regulation of Olfr148 4 0.40 3.76 0.35 92.64
12 INT95944 Binding of Fgf12 11 0.28 8.98 2.53 92.36
13 INT84965 Gene_expression of MAOA 15 0.75 6.9 6.06 91.88
14 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 91.32
15 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 91.32
16 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67 91.32
17 INT121788 Localization of BCS1L 11 0.73 10.16 1.14 90.36
18 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 90.16
19 INT1038 Negative_regulation of F2 26 0.58 15.12 6.75 89.52
20 INT39444 Negative_regulation of Positive_regulation of F2 7 0.59 5.82 1.42 89.52
21 INT20201 Positive_regulation of Fgf12 8 0.43 15.13 0.98 89.00
22 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64 88.96
23 INT192423 Positive_regulation of TARM1 5 0.34 10.77 0.51 88.80
24 INT212534 Transcription of Fgf12 1 0.39 1.37 0 88.68
25 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7 88.36
26 INT76620 Gene_expression of Cnr2 93 0.78 34.7 50.14 88.36
27 INT74377 Regulation of Cnr1 38 0.59 16.93 24.77 88.36
28 INT113317 Regulation of Cnr2 17 0.52 10.27 10.68 88.36
29 INT87819 Localization of CD34 21 0.81 7.69 0.47 87.60
30 INT151525 Gene_expression of Olfr148 7 0.67 8.5 0.74 87.08
31 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49 85.80
32 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 84.16
33 INT76581 Regulation of Negative_regulation of NOS1 14 0.45 7.49 4.4 84.16
34 INT192426 Gene_expression of TARM1 3 0.33 1.98 0 81.08
35 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 78.60
36 INT113659 Gene_expression of ABR 19 0.65 8.49 1.45 76.96
37 INT14690 Localization of CSF2 124 0.80 85.17 27.26 75.80
38 INT232877 Negative_regulation of Binding of ABR 1 0.06 1.88 0.14 74.40
39 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 66.96
40 INT220291 Binding of MARS 1 0.25 0.75 0.05 65.12
41 INT546 Binding of ALB 311 0.48 85.98 60.14 64.96
42 INT220294 Positive_regulation of Gene_expression of MARS 3 0.35 2.45 0.05 62.48
43 INT220295 Gene_expression of MARS 6 0.47 4.74 0.35 62.48
44 INT59302 Positive_regulation of POR 19 0.49 15.18 1.95 61.52
45 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 56.04
46 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 55.68
47 INT61680 Positive_regulation of PVR 23 0.60 23.27 3.86 54.36
48 INT4735 Gene_expression of Acot1 80 0.71 13.22 26.68 49.52
49 INT318930 Binding of COMMD1 1 0.32 1.06 0 49.52
50 INT59454 Regulation of Gene_expression of CSF2 22 0.52 19.67 2.69 45.44
51 INT20059 Protein_catabolism of Ache 15 0.98 3.73 4.87 43.92
52 INT24889 Negative_regulation of CABIN1 36 0.48 16.76 4.73 43.44
53 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 42.32
54 INT276 Regulation of Ache 83 0.62 16.75 25.99 38.28
55 INT11945 Regulation of Chat 38 0.62 7.75 14.97 38.28
56 INT232840 Positive_regulation of Gene_expression of Krt8 1 0.44 4.51 0.42 37.48
57 INT232821 Positive_regulation of Gene_expression of Krt18 11 0.50 4.38 0.31 37.48
58 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 37.12
59 INT232848 Negative_regulation of Gene_expression of Krt18 5 0.36 2.3 0.08 36.64
60 INT232822 Negative_regulation of Gene_expression of Krt8 5 0.36 2.3 0.08 36.64
61 INT199308 Gene_expression of Krt8 37 0.75 23.17 1.06 35.68
62 INT232826 Gene_expression of Krt18 26 0.68 14.24 0.48 35.56
63 INT10173 Binding of Tnf 45 0.48 35.6 14.32 35.52
64 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 35.44
65 INT127432 Gene_expression of Nup62 20 0.71 11.01 0.71 35.40
66 INT232841 Gene_expression of Scap 11 0.02 8.68 0.7 35.40
67 INT213220 Regulation of ASAP2 1 0.01 1.73 0.15 34.16
68 INT232829 Positive_regulation of Scap 6 0.02 2.97 0.11 33.48
69 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 33.28
70 INT217463 Positive_regulation of Nup62 5 0.39 1.79 0.17 33.08
71 INT232830 Positive_regulation of Protein_catabolism of Nup62 3 0.39 0.75 0.15 33.08
72 INT195226 Positive_regulation of ACR 23 0.26 7.85 12.62 32.28
73 INT232834 Protein_catabolism of Nup62 3 0.56 0.8 0.07 32.20
74 INT144766 Binding of BCS1L 11 0.32 8.2 0.13 31.52
75 INT232885 Positive_regulation of Binding of ABR 1 0.07 0.5 0.07 30.00
76 INT224924 Binding of TARM1 4 0.18 3.42 0.39 28.00
77 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 24.24
78 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 23.56
79 INT18773 Localization of ALB 117 0.80 69.18 13.8 22.56
80 INT354483 Gene_expression of Evl 1 0.49 1.92 0.1 18.12
81 INT213221 Negative_regulation of ASAP2 1 0.01 5.83 0.46 8.68
82 INT184995 Binding of HGS 4 0.26 3.1 0.25 5.96
83 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
84 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 5.00
85 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
86 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
87 INT1352 Localization of Acot1 728 0.80 73.01 296.01 5.00
88 INT1308 Localization of Pomc 457 0.81 66.83 217.5 5.00
89 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
90 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 5.00
91 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 5.00
92 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
93 INT7628 Gene_expression of Ltp 273 0.77 70.21 147.87 5.00
94 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 5.00
95 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
96 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
97 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
98 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
99 INT7627 Negative_regulation of Positive_regulation of Ltp 162 0.50 41.2 106.27 5.00
100 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 5.00
101 INT13276 Regulation of Ltp 107 0.53 30.78 69.13 5.00
102 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
103 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 5.00
104 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 5.00
105 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 5.00
106 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
107 INT1316 Positive_regulation of Acot1 129 0.60 18.86 56.13 5.00
108 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 5.00
109 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
110 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42 5.00
111 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
112 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
113 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 5.00
114 INT3188 Regulation of Localization of Acot1 84 0.59 8.94 38.56 5.00
115 INT163134 Gene_expression of ACR 78 0.65 30.39 38.48 5.00
116 INT1354 Negative_regulation of Acot1 87 0.43 15.01 36.44 5.00
117 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08 5.00
118 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 5.00
119 INT4403 Binding of CYP2B6 113 0.48 21.17 33.83 5.00
120 INT99610 Localization of MMP9 126 0.79 48.46 32.67 5.00
121 INT20307 Positive_regulation of Cyp2e1 70 0.70 23.59 32.49 5.00
122 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72 5.00
123 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7 5.00
124 INT1158 Regulation of Agt 106 0.61 29.4 30.29 5.00
125 INT1079 Positive_regulation of Ache 104 0.70 23.52 30.28 5.00
126 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 5.00
127 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 5.00
128 INT177581 Regulation of Fig4 113 0.41 39.26 27.75 5.00
129 INT2569 Gene_expression of Ache 120 0.78 26.29 26.89 5.00
130 INT32826 Positive_regulation of Gene_expression of Ltp 52 0.45 10.34 26.8 5.00
131 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
132 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27 5.00
133 INT57192 Binding of Ltp 43 0.41 17.48 24.96 5.00
134 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 5.00
135 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07 5.00
136 INT23257 Regulation of CRP 127 0.62 100.05 21.87 5.00
137 INT171820 Localization of Fig4 144 0.65 27.38 20.88 5.00
138 INT15796 Regulation of IL2 66 0.61 25.43 20.62 5.00
139 INT20305 Gene_expression of Cyp2e1 53 0.78 19.75 19.54 5.00
140 INT76924 Positive_regulation of Slc17a5 71 0.70 41.21 19.31 5.00
141 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 5.00
142 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01 5.00
143 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04 5.00
144 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86 5.00
145 INT19071 Localization of Ache 66 0.81 5.1 16.27 5.00
146 INT14152 Gene_expression of Slc17a5 46 0.61 20.01 15.9 5.00
147 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 5.00
148 INT4851 Positive_regulation of Chat 53 0.70 9.21 15.11 5.00
149 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 5.00
150 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42 5.00
151 INT4736 Gene_expression of Chat 67 0.77 17.15 14.24 5.00
152 INT22046 Negative_regulation of IRF6 52 0.43 25.69 14.13 5.00
153 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99 5.00
154 INT5806 Regulation of Edn1 63 0.62 23.46 13.88 5.00
155 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 5.00
156 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 5.00
157 INT17565 Regulation of Gpt 85 0.60 43.64 13.68 5.00
158 INT28458 Localization of Slc6a3 31 0.76 2.33 12.49 5.00
159 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 5.00
160 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3 5.00
161 INT148207 Gene_expression of CTLA4 53 0.77 29.13 12.07 5.00
162 INT36287 Binding of CD4 96 0.47 58.93 11.88 5.00
163 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 5.00
164 INT15305 Positive_regulation of Mtor 51 0.67 8.28 11 5.00
165 INT54466 Negative_regulation of Gene_expression of Ltp 19 0.38 5.44 10.91 5.00
166 INT1252 Binding of Ache 46 0.48 9.94 10.25 5.00
167 INT73504 Binding of CD28 35 0.45 15.99 10.04 5.00
168 INT81929 Negative_regulation of Gene_expression of IL10 41 0.57 27.99 9.87 5.00
169 INT62166 Positive_regulation of Gene_expression of Gpt 64 0.50 39.13 9.69 5.00
170 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 5.00
171 INT80036 Positive_regulation of FAS 42 0.67 42.22 9.4 5.00
172 INT101105 Positive_regulation of FUT1 62 0.30 55.96 9.28 5.00
173 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19 5.00
174 INT107087 Positive_regulation of Gene_expression of Cyp2e1 20 0.70 8.89 9.04 5.00
175 INT14301 Binding of CSF2 82 0.48 67.95 8.98 5.00
176 INT20371 Gene_expression of Cd8a 125 0.60 67.59 8.97 5.00
177 INT22383 Binding of IL2 59 0.48 39.06 8.56 5.00
178 INT80034 Positive_regulation of Gene_expression of FAS 32 0.67 30.34 8.51 5.00
179 INT15308 Localization of Chat 29 0.81 2.35 8.47 5.00
180 INT43820 Positive_regulation of Twist1 75 0.59 42.15 8.47 5.00
181 INT72337 Positive_regulation of Positive_regulation of Nos2 37 0.65 17.02 8.11 5.00
182 INT13539 Gene_expression of LTA 39 0.62 22.55 8.07 5.00
183 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 5.00
184 INT73595 Positive_regulation of BAX 61 0.61 56.97 7.82 5.00
185 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 5.00
186 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47 5.00
187 INT30777 Negative_regulation of SELL 20 0.56 18.05 7.32 5.00
188 INT36726 Regulation of Gene_expression of Ltp 14 0.46 4.81 7.05 5.00
189 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 5.00
190 INT84685 Regulation of BCL2 67 0.60 72.96 6.65 5.00
191 INT25022 Binding of PAEP 66 0.42 22.83 6.59 5.00
192 INT4060 Gene_expression of Bche 17 0.70 5.23 6.59 5.00
193 INT5871 Binding of IFNA2 38 0.48 20.35 6.46 5.00
194 INT10094 Negative_regulation of ALPP 36 0.37 20.45 6.45 5.00
195 INT86805 Localization of HGF 49 0.71 28.48 6.35 5.00
196 INT22128 Positive_regulation of HIVEP1 61 0.43 70.52 6.07 5.00
197 INT26585 Gene_expression of Vim 117 0.77 39.97 6 5.00
198 INT45275 Gene_expression of CSH1 39 0.62 9.39 5.85 5.00
199 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38 5.00
200 INT75800 Gene_expression of Cyp2a5 12 0.77 5.15 5.37 5.00
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