D:Endometrial Cancer

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Disease Term
Synonyms Cancer Endometrial, Cancer Endometrium, Cancer Of Endometrium, Cancer Of The Endometrium, CANCERS ENDOMETRIAL, Cancers Endometrium, Carcinoma Endometrial, CARCINOMA OF ENDOMETRIUM, Carcinomas Endometrial, Endometrial Cancers, ENDOMETRIAL CARCINOMA
Documents 267
Hot Single Events 200
Hot Interactions 14

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Endometrial Cancer. They are ordered first by their relevance to Endometrial Cancer and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT304023 SFRP1 Regulation of Binding of MSI1 1 0.04 1.78 0 100.00
2 INT304016 SFRP4 Regulation of Binding of MSI1 1 0.04 1.78 0 100.00
3 INT176130 AKT1 Regulation of Gene_expression of COX18 1 0.13 0.82 0.11 99.84
4 INT176137 Negative_regulation of Binding of AKT1 and PIK3CG 1 0.17 0.25 0 97.60
5 INT176131 Binding of AKT1 and PIK3CG 2 0.15 1.08 0 97.60
6 INT304014 Binding of MSI1 and SGCG 1 0.00 1.92 0 97.48
7 INT305350 Pten Regulation of Phosphorylation of Akt1 1 0.05 0.95 0 95.36
8 INT304028 MDM2 Regulation of TP53 1 0.19 1.11 0 94.04
9 INT304012 Binding of AKT1 and PIK3CA 1 0.28 1.14 0 94.00
10 INT304024 Binding of AKT1 and PTEN 1 0.33 1.08 0 94.00
11 INT304020 AR Regulation of TP53 1 0.24 1.11 0 93.68
12 INT304027 Negative_regulation of PTEN Positive_regulation of Positive_regulation of AKT1 1 0.32 1.86 0 90.72
13 INT321642 Binding of Cd3e and Spn 1 0.00 1.08 0 86.36
14 INT246414 TLR4 Regulation of Gene_expression of TLR3 1 0.35 1.16 0.17 84.96
15 INT176135 AKT1 Regulation of Localization of CYCS 1 0.43 2.16 0.35 76.96
16 INT176134 AKT1 Regulation of Gene_expression of BIRC3 1 0.08 1.09 0.17 76.96
17 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17 76.96
18 INT304013 Binding of SUZ12 and JAZF1 1 0.30 1.89 0 74.76
19 INT291355 CXCL12 Positive_regulation of Gene_expression of HGF 1 0.06 1.53 0.06 73.00
20 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 73.00
21 INT173771 Gh1 Regulation of Transcription of Esr1 1 0.00 0.13 0 72.72
22 INT173772 Gh1 Regulation of Ift20 1 0.05 0.13 0 72.72
23 INT173770 Gh1 Regulation of Esr1 1 0.00 0.13 0 72.72
24 INT173768 Gh1 Regulation of Igf1 1 0.04 0.13 0 72.72
25 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0 72.68
26 INT304025 Binding of PIK3CA and TP53 1 0.30 0.67 0 72.68
27 INT304015 Binding of PIK3CA and PIK3CG 1 0.09 0.67 0 72.68
28 INT304026 Binding of PIK3CG and PTEN 1 0.11 0.62 0 72.68
29 INT305336 TP53 Negative_regulation of Phosphorylation of RB1 1 0.29 0.96 0 69.04
30 INT190061 Binding of MLH1 and Mlh1 1 0.01 0.92 0 68.96
31 INT190062 Binding of MLH1 and Msh2 1 0.01 0.91 0 68.96
32 INT246413 TLR4 Regulation of TLR3 1 0.28 0.81 0.05 64.76
33 INT304018 Regulation of Binding of PIK3CG and TP53 1 0.12 0.73 0 62.28
34 INT304017 Regulation of Binding of AKT1 and TP53 1 0.32 0.73 0 62.28
35 INT304022 Binding of PIK3CG and TP53 1 0.10 0.72 0 61.60
36 INT304019 Binding of AKT1 and TP53 1 0.27 0.72 0 61.40
37 INT350106 Binding of SLC4A3 and SLC4A1 1 0.13 2.78 0.09 52.32
38 INT260267 Binding of TFAM and TP53 2 0.37 2.1 0.03 50.00
39 INT342854 Binding of Casp8 and Mapk1 1 0.05 2.18 0 41.60
40 INT342852 Binding of Casp8 and Dedd2 1 0.01 1.12 0 41.60
41 INT339096 Ezh2 Regulation of Rcc1 1 0.02 1.1 0 26.36
42 INT190044 Binding of Msh2 and Msh6 2 0.32 0.77 0.05 11.36
43 INT291358 Binding of CXCL12 and CXCR7 1 0.20 0.11 0.09 7.36
44 INT246411 Positive_regulation of Binding of TLR3 and TLR4 1 0.51 0 0 5.64
45 INT246412 Binding of TLR3 and TLR4 1 0.38 0 0 5.04
46 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27 5.00
47 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 5.00
48 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02 5.00
49 INT199976 EGF Regulation of ITGB3BP 1 0.02 0.77 0.57 5.00
50 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5 5.00
51 INT199974 ESR1 Negative_regulation of Gene_expression of ITGB3BP 1 0.05 0.47 0.38 5.00
52 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35 5.00
53 INT199978 ESR1 Regulation of ITGB3BP 1 0.03 0.39 0.28 5.00
54 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25 5.00
55 INT302169 PTGER2 Positive_regulation of DYNC1LI1 1 0.02 1.51 0.25 5.00
56 INT199971 IL6 Positive_regulation of ESR1 1 0.08 0.84 0.24 5.00
57 INT190052 Binding of Cdx2 and Ebp 1 0.08 0.82 0.24 5.00
58 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23 5.00
59 INT190045 Binding of Ebp and Scrib 1 0.10 0.79 0.22 5.00
60 INT291352 Positive_regulation of CXCL12 Positive_regulation of ERBB2 1 0.17 0.88 0.22 5.00
61 INT291348 IL8 Positive_regulation of Phosphorylation of SHC1 1 0.11 1.16 0.2 5.00
62 INT291346 IL8 Positive_regulation of Binding of EGFR and GRB2 1 0.15 1.17 0.2 5.00
63 INT279965 STAT3 Regulation of Transcription of BCL2L1 1 0.10 2.31 0.19 5.00
64 INT193214 Binding of PTGER2 and PTGER4 2 0.08 2.51 0.18 5.00
65 INT291354 CXCL12 Positive_regulation of EPHB2 1 0.42 2.02 0.16 5.00
66 INT209581 Twist1 Positive_regulation of Gene_expression of VEGFA 6 0.06 7.86 0.16 5.00
67 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14 5.00
68 INT302144 CDKN2A Regulation of CDKN1A 1 0.11 0.51 0.14 5.00
69 INT291347 Positive_regulation of TXK Positive_regulation of CXCR4 Positive_regulation of EPHB2 1 0.02 0.61 0.13 5.00
70 INT302156 AKT1 Positive_regulation of E2F2 1 0.02 0.88 0.13 5.00
71 INT291349 CXCR4 Positive_regulation of EPHB2 1 0.42 1.87 0.13 5.00
72 INT302161 AKT1 Negative_regulation of CASP9 1 0.03 0.87 0.11 5.00
73 INT291353 IL8 Positive_regulation of Binding of EGFR 1 0.32 0.52 0.1 5.00
74 INT191184 Binding of EGFR and GRB2 7 0.35 1.06 0.1 5.00
75 INT302287 Twist1 Positive_regulation of Positive_regulation of PTGER2 1 0.03 1.16 0.1 5.00
76 INT302288 Twist1 Positive_regulation of PTGER2 1 0.03 1.16 0.1 5.00
77 INT291351 Binding of EGFR and SHC1 1 0.05 0.57 0.1 5.00
78 INT291350 IL8 Positive_regulation of Phosphorylation of EGFR 1 0.32 0.52 0.1 5.00
79 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09 5.00
80 INT302167 PTGER2 Positive_regulation of EGFR 1 0.10 3.08 0.09 5.00
81 INT302178 CDKN1C Regulation of CDKN2A 1 0.09 0.26 0.08 5.00
82 INT302158 CDKN1A Regulation of CDKN2A 1 0.04 0.26 0.08 5.00
83 INT199973 ESR1 Negative_regulation of EEF1B2P2 1 0.01 0.46 0.08 5.00
84 INT302139 LAMTOR1 Regulation of CDKN2A 1 0.08 0.26 0.08 5.00
85 INT302157 MRPL28 Regulation of CDKN2A 1 0.09 0.26 0.08 5.00
86 INT302148 IFI27 Regulation of CDKN2A 1 0.11 0.26 0.08 5.00
87 INT302290 Birc5 Regulation of BAK1 1 0.21 1.22 0.07 5.00
88 INT213933 AR Negative_regulation of Cyp19a1 1 0.07 0.79 0.07 5.00
89 INT302131 Negative_regulation of SOD2 Regulation of BAK1 1 0.09 1.22 0.07 5.00
90 INT302289 Negative_regulation of Birc5 Regulation of BAK1 1 0.20 1.22 0.07 5.00
91 INT302152 PTGER2 Positive_regulation of EMR1 1 0.01 2.02 0.07 5.00
92 INT302128 SOD2 Regulation of BAK1 1 0.09 1.22 0.07 5.00
93 INT302160 LAMTOR1 Regulation of CDKN1A 1 0.08 0.26 0.06 5.00
94 INT302147 PTGER2 Positive_regulation of BAK1 1 0.06 2.08 0.06 5.00
95 INT302150 MRPL28 Regulation of CDKN1B 1 0.09 0.26 0.06 5.00
96 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 0.01 0.69 0.06 5.00
97 INT302177 PTGER2 Positive_regulation of BCL2 1 0.04 2.08 0.06 5.00
98 INT302175 BAX Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06 5.00
99 INT302129 BAX Regulation of Positive_regulation of CASP3 1 0.02 0.69 0.06 5.00
100 INT302155 TP53 Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06 5.00
101 INT302136 LAMTOR1 Regulation of CDKN1B 1 0.08 0.26 0.06 5.00
102 INT302127 MRPL28 Regulation of CDKN1A 1 0.09 0.26 0.06 5.00
103 INT302138 PTGER2 Positive_regulation of Gene_expression of BAK1 1 0.06 2.08 0.06 5.00
104 INT302164 PTEN Regulation of PIK3CD 1 0.16 1.13 0.06 5.00
105 INT302165 PTGER2 Positive_regulation of Localization of EGFR 1 0.06 1.73 0.05 5.00
106 INT302133 IFI27 Regulation of CDKN1B 1 0.11 0.26 0.05 5.00
107 INT302130 CDKN1A Regulation of CDKN1B 1 0.04 0.26 0.05 5.00
108 INT302176 CDKN1C Regulation of CDKN1A 1 0.09 0.26 0.05 5.00
109 INT302141 CDKN1C Regulation of CDKN1B 1 0.09 0.26 0.05 5.00
110 INT302140 PTGER2 Positive_regulation of VEGFA 1 0.11 1.87 0.05 5.00
111 INT302163 IFI27 Regulation of CDKN1A 1 0.11 0.26 0.05 5.00
112 INT190050 Binding of Msh2 and Pms2 2 0.32 0.49 0.04 5.00
113 INT302166 Positive_regulation of PTGER2 Positive_regulation of EGFR 1 0.07 1.49 0.04 5.00
114 INT302291 Positive_regulation of EGFR Positive_regulation of Myc 1 0.18 1.3 0.04 5.00
115 INT302162 CASP8 Positive_regulation of CASP3 2 0.01 2.07 0.04 5.00
116 INT190046 Binding of Msh3 and Pms2 2 0.25 0.5 0.04 5.00
117 INT302159 TSC1 Positive_regulation of Transcription of CDKN1A 1 0.00 0.28 0.03 5.00
118 INT302153 PTGER2 Positive_regulation of Localization of AREG 1 0.06 1.1 0.03 5.00
119 INT291356 CXCL12 Positive_regulation of AKT1 1 0.04 1.28 0.03 5.00
120 INT302126 PTGER2 Positive_regulation of SRC 1 0.11 1.08 0.03 5.00
121 INT302134 TP53 Positive_regulation of Transcription of CDKN1A 1 0.04 0.28 0.03 5.00
122 INT302171 PTGER4 Positive_regulation of RASGRP1 1 0.01 1.03 0.03 5.00
123 INT291357 CXCR4 Positive_regulation of AKT1 1 0.08 1.27 0.03 5.00
124 INT280543 Binding of GAST and STAT1 1 0.05 0.58 0 5.00
125 INT144030 STAT3 Regulation of CCND1 2 0.09 1.05 0 5.00
126 INT185852 Binding of BAK1 and BAX 3 0.29 2.5 0 5.00
127 INT199975 ESR1 Positive_regulation of PGR 1 0.05 0.11 0 5.00
128 INT302145 Positive_regulation of AKT1 Positive_regulation of Phosphorylation of BAD 1 0.07 0.9 0 5.00
129 INT302179 PTGER2 Positive_regulation of Phosphorylation of IFI27 1 0.05 0.75 0 5.00
130 INT198011 Binding of BAX and MCL1 2 0.20 3.04 0 5.00
131 INT292454 Binding of BAD and BCL2 2 0.03 1.73 0 5.00
132 INT173769 Dlat Regulation of Ghr 1 0.04 0 0 5.00
133 INT302137 Binding of BAD and BAK1 1 0.07 0.93 0 5.00
134 INT353872 Binding of KCNH1 and KCNH2 1 0.25 0.98 0 5.00
135 INT302174 Positive_regulation of SRC Positive_regulation of Phosphorylation of STAT3 1 0.11 1.01 0 5.00
136 INT302142 PTGER3 Positive_regulation of SRC 1 0.09 1.07 0 5.00
137 INT185856 Binding of BAD and BCL2L1 4 0.39 2.73 0 5.00
138 INT302154 STAT3 Regulation of Transcription of CCND1 1 0.04 0.99 0 5.00
139 INT353870 Binding of KCNH1 and KCNH2 Negative_regulation of KCNH1 1 0.28 0.98 0 5.00
140 INT280546 Binding of KIT and TP63 1 0.01 1.19 0 5.00
141 INT190049 Binding of Mlh1 and Msh3 1 0.24 0.22 0 5.00
142 INT190048 Binding of Mlh1 and Msh2 1 0.31 0.22 0 5.00
143 INT199988 ESR1 Positive_regulation of Fos 1 0.40 0.18 0 5.00
144 INT193193 Binding of CRS and RAPH1 1 0.12 1.47 0 5.00
145 INT302149 Binding of BCL2L1 and MCL1 1 0.03 1.1 0 5.00
146 INT353871 Negative_regulation of Binding of KCNH1 and KCNH2 1 0.30 0.98 0 5.00
147 INT302172 Binding of BAD and BAX 1 0.06 0.93 0 5.00
148 INT199977 ESR1 Positive_regulation of JUN 1 0.03 0.18 0 5.00
149 INT324908 TP53 Regulation of Gene_expression of BAX 1 0.47 1.33 0 5.00
150 INT190047 Binding of Msh2 and Msh3 1 0.24 0.23 0 5.00
151 INT302132 Negative_regulation of Binding of BAD and BAK1 1 0.06 0.93 0 5.00
152 INT190051 Binding of Ebp and Mrc1 1 0.04 0.63 0 5.00
153 INT324909 Negative_regulation of TP53 Positive_regulation of Negative_regulation of BAX 1 0.36 1.33 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Endometrial Cancer. They are ordered first by their pain relevance and then by number of times they were reported in Endometrial Cancer. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT304052 Binding of MSI1 8 0.05 12.19 0 100.00
2 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 100.00
3 INT179885 Regulation of PTEN 8 0.26 11.88 2.18 100.00
4 INT130705 Gene_expression of TFAM 50 0.77 38.85 2.79 100.00
5 INT236621 Regulation of KRAS 7 0.53 6.16 0 100.00
6 INT282953 Regulation of MSI1 2 0.03 1.63 0.03 100.00
7 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37 100.00
8 INT198037 Regulation of PIK3CA 2 0.28 2.63 0 100.00
9 INT200670 Gene_expression of AKT2 25 0.75 16.25 3 100.00
10 INT97797 Localization of TLR4 18 0.77 13.78 6 100.00
11 INT186797 Localization of TLR3 2 0.70 2.69 0.12 100.00
12 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 99.98
13 INT92139 Binding of MLH1 12 0.42 15.62 1 99.98
14 INT132760 Gene_expression of Pgr 47 0.66 28.17 2.85 99.98
15 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 99.98
16 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98 99.96
17 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 99.96
18 INT170852 Negative_regulation of Gene_expression of IFI27 16 0.55 8.62 0.05 99.96
19 INT130647 Regulation of Gene_expression of CXCL12 6 0.39 5.01 1.38 99.96
20 INT193815 Regulation of Gene_expression of CXCR4 17 0.61 20.27 1.15 99.96
21 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 99.88
22 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63 99.84
23 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72 99.84
24 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5 99.84
25 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.84
26 INT292659 Positive_regulation of Gene_expression of FOLR1 2 0.47 1.59 0.14 99.84
27 INT37490 Negative_regulation of Cyp1b1 3 0.30 1.57 0.68 99.84
28 INT103674 Positive_regulation of Gene_expression of CXCR4 32 0.69 37.1 3.08 99.84
29 INT80420 Gene_expression of IFI27 145 0.78 63.61 8.83 99.80
30 INT134795 Positive_regulation of Scrib 30 0.22 36.91 2.81 99.80
31 INT211581 Binding of Pms2 2 0.32 2.49 0.04 99.76
32 INT304058 Positive_regulation of MSI1 1 0.07 2.74 0 99.74
33 INT119641 Gene_expression of EBAG9 25 0.76 33.2 3.96 99.72
34 INT55047 Gene_expression of GNRHR 8 0.78 5.2 0.53 99.68
35 INT137382 Negative_regulation of Gene_expression of KRT20 22 0.58 12.29 1.29 99.68
36 INT55048 Transcription of GNRHR 2 0.69 0.63 0.13 99.68
37 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 99.64
38 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 99.64
39 INT105948 Gene_expression of AURKA 5 0.65 4.26 0.03 99.64
40 INT89401 Negative_regulation of Phosphorylation of AKT1 68 0.58 35.61 2.8 99.64
41 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 99.64
42 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 99.64
43 INT25208 Gene_expression of IGF2 43 0.74 30.64 2.31 99.64
44 INT220206 Gene_expression of CCNB2 4 0.67 3.75 1.16 99.64
45 INT304066 Gene_expression of BUB1 1 0.07 1.41 0 99.64
46 INT275575 Gene_expression of FOLR1 12 0.66 2.81 0.8 99.64
47 INT146546 Gene_expression of MSI1 22 0.48 22.91 1.15 99.60
48 INT176154 Gene_expression of PIK3CA 6 0.55 10.43 0.03 99.60
49 INT119834 Phosphorylation of PTEN 12 0.79 6.78 0.75 99.60
50 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 99.60
51 INT139237 Negative_regulation of Gene_expression of CDH1 23 0.57 24.31 1.28 99.56
52 INT66227 Gene_expression of COX18 41 0.50 26.91 6.26 99.56
53 INT108485 Gene_expression of CXCL12 61 0.75 49.34 13.79 99.54
54 INT86909 Negative_regulation of MSH2 9 0.41 12.65 1.7 99.52
55 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02 99.52
56 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57 99.48
57 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 99.48
58 INT55046 Binding of GNRHR 1 0.37 0.53 0 99.48
59 INT5131 Gene_expression of GNRH1 109 0.78 28.79 23.94 99.46
60 INT107983 Gene_expression of MSH6 6 0.51 5.57 0.27 99.44
61 INT210399 Gene_expression of IGF2R 22 0.65 17.1 1.23 99.44
62 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94 99.44
63 INT190038 Binding of Mlh1 2 0.28 3.11 0 99.44
64 INT181920 Gene_expression of MSH3 2 0.50 2.54 0.18 99.44
65 INT190053 Gene_expression of CASP5 3 0.45 2.46 0 99.44
66 INT190035 Binding of Msh6 2 0.28 2.72 0 99.44
67 INT92142 Binding of MSH2 5 0.46 5.64 0.75 99.44
68 INT319141 Regulation of MTUS1 1 0.00 1.56 0 99.42
69 INT180580 Binding of HEYL 7 0.17 4.49 1.15 99.42
70 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 99.40
71 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 99.40
72 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 99.36
73 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 99.36
74 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54 99.32
75 INT185004 Positive_regulation of TFF3 4 0.47 3.77 0 99.32
76 INT304060 Positive_regulation of AGR2 2 0.70 13 0.63 99.32
77 INT304072 Positive_regulation of FOXA2 1 0.15 1.29 0 99.32
78 INT12089 Positive_regulation of MSX2 4 0.46 3.92 0.39 99.32
79 INT304045 Transcription of PTEN 2 0.51 4.12 1.4 99.32
80 INT86908 Negative_regulation of MLH1 7 0.43 6.98 1.12 99.16
81 INT200671 Gene_expression of AKT3 4 0.69 1.88 0.13 99.16
82 INT108482 Positive_regulation of Gene_expression of CXCL12 7 0.53 9.72 2.36 99.16
83 INT181744 Negative_regulation of Gene_expression of MLH1 3 0.05 7.67 0.12 99.06
84 INT109450 Positive_regulation of Phosphorylation of AKT1 62 0.64 25.18 4.21 99.00
85 INT190014 Regulation of Pten 8 0.62 6.03 1.2 98.96
86 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 98.92
87 INT75001 Gene_expression of Cyp1b1 11 0.66 4.23 0.48 98.92
88 INT123130 Positive_regulation of Positive_regulation of AKT1 22 0.49 11.77 1.83 98.92
89 INT89774 Gene_expression of NR4A1 13 0.77 9.47 1.02 98.90
90 INT107985 Gene_expression of MLH1 29 0.67 31.31 1.46 98.86
91 INT304073 Regulation of CCNB2 1 0.10 1.39 0 98.80
92 INT304061 Regulation of BUB1 1 0.07 1.39 0 98.80
93 INT304075 Regulation of AURKA 1 0.15 1.38 0 98.80
94 INT291365 Positive_regulation of Gene_expression of PIK3CA 2 0.41 5.76 0 98.76
95 INT319136 Binding of Mad2l1 1 0.04 1.24 0 98.76
96 INT319140 Binding of ZIC2 1 0.36 1.24 0 98.76
97 INT1317 Negative_regulation of Sds 23 0.48 6.97 5.03 98.74
98 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 98.72
99 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53 98.60
100 INT55597 Negative_regulation of Gpx1 59 0.55 28.3 8.83 98.48
101 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 98.48
102 INT305352 Gene_expression of HOXA11 1 0.23 1.22 0 98.38
103 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 98.36
104 INT185222 Regulation of Gene_expression of EBAG9 5 0.60 4.98 0.64 98.28
105 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 98.24
106 INT250899 Gene_expression of Thbs2 17 0.75 4.97 0.13 98.22
107 INT109975 Positive_regulation of Kras 14 0.45 12.72 1.68 98.20
108 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45 98.16
109 INT115982 Positive_regulation of KRT7 18 0.50 19.81 1.14 98.14
110 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 98.12
111 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 98.12
112 INT165516 Regulation of MSX2 8 0.23 3.41 0.09 98.04
113 INT106613 Regulation of IFI27 6 0.57 3.12 0.66 98.00
114 INT59784 Binding of DES 22 0.47 19.48 2.27 98.00
115 INT32905 Gene_expression of Mrc1 18 0.58 11.07 3.54 97.98
116 INT7234 Binding of GNRH1 43 0.47 21.59 12.36 97.88
117 INT176150 Localization of PIK3CA 2 0.73 0.22 0.03 97.84
118 INT176160 Positive_regulation of Localization of PIK3CA 1 0.13 0.22 0.03 97.84
119 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51 97.68
120 INT291934 Regulation of FOXA2 2 0.26 2.15 0 97.64
121 INT38674 Regulation of KRT20 32 0.44 19 2.15 97.64
122 INT61513 Positive_regulation of Gpx1 71 0.64 37.91 17.07 97.56
123 INT86600 Gene_expression of KCNH2 37 0.78 14.88 6.14 97.56
124 INT79270 Gene_expression of MKI67 113 0.77 63.52 3.38 97.46
125 INT339094 Gene_expression of Ezh2 1 0.78 67.79 0.05 97.40
126 INT200666 Transcription of AKT1 8 0.66 4.23 0.2 97.40
127 INT219360 Regulation of MMP11 2 0.54 1.71 0.03 97.32
128 INT184985 Regulation of TFF3 2 0.26 1.43 0.07 97.28
129 INT87406 Gene_expression of GSTP1 16 0.77 11.37 0.35 97.28
130 INT95328 Gene_expression of Gstp1 11 0.61 8.59 0.48 97.28
131 INT305348 Gene_expression of Peg3 2 0.25 2.36 0.31 97.28
132 INT140637 Negative_regulation of IFI27 11 0.40 9.48 0.69 97.20
133 INT211714 Regulation of Gene_expression of VIM 4 0.43 3.77 0.52 97.20
134 INT304068 Regulation of VPS11 1 0.12 1.24 0 97.04
135 INT304079 Regulation of AGR2 2 0.27 1.2 0 97.04
136 INT8546 Positive_regulation of MUC16 99 0.69 74.98 11.26 97.00
137 INT6699 Positive_regulation of ADRA1D 65 0.70 22.72 20.31 97.00
138 INT148882 Regulation of LTF 9 0.12 4.8 0.44 96.80
139 INT207233 Transcription of KRAS 3 0.48 1.56 0.03 96.80
140 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 96.80
141 INT192676 Binding of PTEN 14 0.46 10.58 3.06 96.68
142 INT304051 Regulation of SCGB2A1 1 0.17 1.19 0 96.60
143 INT176147 Regulation of Phosphorylation of AKT1 14 0.41 6.41 1.13 96.60
144 INT304076 Regulation of Localization of KRAS 2 0.36 2.39 0 96.56
145 INT304062 Regulation of Localization of PTEN 1 0.43 1.29 0 96.56
146 INT207729 Regulation of FGFR2 4 0.22 2.35 0 96.52
147 INT305351 Positive_regulation of Regulation of FGFR2 2 0.37 0.97 0 96.52
148 INT211715 Negative_regulation of Gene_expression of MSH6 1 0.06 1.09 0 96.36
149 INT73731 Binding of RAPH1 9 0.33 14.58 0.5 96.16
150 INT120761 Positive_regulation of GSTP1 3 0.50 3.4 0.19 96.14
151 INT8547 Gene_expression of MUC16 116 0.78 75.97 12.18 96.12
152 INT86919 Negative_regulation of PIK3CG 40 0.57 21.16 3.97 95.96
153 INT161322 Localization of PTEN 9 0.73 5.65 0.57 95.68
154 INT180396 Localization of KRAS 3 0.69 2.89 0 95.68
155 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 95.56
156 INT37722 Gene_expression of NCAM1 103 0.75 81.57 14.18 95.56
157 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 95.40
158 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 95.36
159 INT14823 Gene_expression of MET 103 0.75 51.92 32.48 95.28
160 INT176533 Positive_regulation of Gene_expression of MET 13 0.67 7.17 0.06 95.28
161 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14 95.04
162 INT74944 Positive_regulation of Gene_expression of HGF 31 0.70 17.69 6.68 95.04
163 INT110924 Regulation of BMPR2 3 0.17 1.75 0.54 95.00
164 INT190028 Positive_regulation of Mrc1 10 0.22 2.94 2.26 94.92
165 INT50558 Negative_regulation of PCNA 31 0.57 13.97 2.3 94.80
166 INT23956 Negative_regulation of DES 12 0.42 10.84 1.82 94.80
167 INT128472 Negative_regulation of CD34 7 0.42 3.92 0.58 94.80
168 INT22129 Positive_regulation of Gene_expression of CAT 11 0.67 4.23 2.37 94.72
169 INT11048 Gene_expression of CD69 59 0.67 42.85 6.4 94.60
170 INT176144 Positive_regulation of Phosphorylation of PTEN 1 0.36 0.29 0.04 94.44
171 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18 94.36
172 INT3593 Gene_expression of ADRA1D 70 0.75 29.48 20.87 94.32
173 INT35366 Binding of AR 87 0.47 30.52 8.9 94.20
174 INT133488 Negative_regulation of Phosphorylation of PTEN 4 0.41 1.88 0.26 94.16
175 INT105949 Positive_regulation of Gene_expression of AURKA 3 0.49 1.91 0.03 94.00
176 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 93.76
177 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73 93.76
178 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 93.68
179 INT53584 Regulation of Gpx1 19 0.62 14.38 3.48 93.60
180 INT5164 Negative_regulation of Ldlr 83 0.58 55.01 7.87 93.52
181 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 93.52
182 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75 93.16
183 INT101902 Negative_regulation of Mki67 12 0.39 7.92 0.34 93.12
184 INT155696 Gene_expression of PIK3CG 16 0.65 8.54 1.02 93.08
185 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 92.80
186 INT84894 Gene_expression of Calb2 45 0.73 24.65 7.81 92.16
187 INT107991 Positive_regulation of Gene_expression of MSH6 3 0.38 1.35 0 92.12
188 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 92.04
189 INT176157 Phosphorylation of COX18 1 0.17 0.55 0 91.80
190 INT52980 Positive_regulation of Dlat 20 0.37 5.14 4.06 91.44
191 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 91.20
192 INT184477 Negative_regulation of Pten 27 0.59 15.61 2.8 90.92
193 INT305346 Positive_regulation of Negative_regulation of Pten 2 0.41 0.91 0 90.92
194 INT101866 Positive_regulation of Gene_expression of AKT1 49 0.52 17.47 2.14 90.84
195 INT151171 Positive_regulation of Pten 20 0.55 13.3 3.54 90.40
196 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 90.08
197 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 90.08
198 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31 90.04
199 INT119832 Positive_regulation of Gene_expression of PTEN 12 0.49 7.12 1.19 89.96
200 INT75137 Regulation of Akt1 74 0.48 37.89 9.7 89.92
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