D:Endometrial Hyperplasia

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Atypical Endometrial Hyperplasia, Atypical Endometrial Hyperplasias, COMPLEX ENDOMETRIAL HYPERPLASIA, Complex Endometrial Hyperplasias, Endometrial Hyperplasia Atypical, Endometrial Hyperplasia Complex, Endometrial Hyperplasia Simple, Endometrial Hyperplasias, Endometrial Hyperplasias Atypical, Endometrial Hyperplasias Complex, Endometrial Hyperplasias Simple
Documents 26
Hot Single Events 14
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Endometrial Hyperplasia. They are ordered first by their relevance to Endometrial Hyperplasia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT304027 Negative_regulation of PTEN Positive_regulation of Positive_regulation of AKT1 1 0.32 1.86 0 93.32
2 INT304023 SFRP1 Regulation of Binding of MSI1 1 0.04 1.78 0 9.20
3 INT304016 SFRP4 Regulation of Binding of MSI1 1 0.04 1.78 0 8.80
4 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0 5.00
5 INT304020 AR Regulation of TP53 1 0.24 1.11 0 5.00
6 INT304022 Binding of PIK3CG and TP53 1 0.10 0.72 0 5.00
7 INT304028 MDM2 Regulation of TP53 1 0.19 1.11 0 5.00
8 INT304014 Binding of MSI1 and SGCG 1 0.00 1.92 0 5.00
9 INT304012 Binding of AKT1 and PIK3CA 1 0.28 1.14 0 5.00
10 INT304018 Regulation of Binding of PIK3CG and TP53 1 0.12 0.73 0 5.00
11 INT304025 Binding of PIK3CA and TP53 1 0.30 0.67 0 5.00
12 INT304015 Binding of PIK3CA and PIK3CG 1 0.09 0.67 0 5.00
13 INT304019 Binding of AKT1 and TP53 1 0.27 0.72 0 5.00
14 INT304026 Binding of PIK3CG and PTEN 1 0.11 0.62 0 5.00
15 INT305350 Pten Regulation of Phosphorylation of Akt1 1 0.05 0.95 0 5.00
16 INT305336 TP53 Negative_regulation of Phosphorylation of RB1 1 0.29 0.96 0 5.00
17 INT304017 Regulation of Binding of AKT1 and TP53 1 0.32 0.73 0 5.00
18 INT304013 Binding of SUZ12 and JAZF1 1 0.30 1.89 0 5.00
19 INT304024 Binding of AKT1 and PTEN 1 0.33 1.08 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Endometrial Hyperplasia. They are ordered first by their pain relevance and then by number of times they were reported in Endometrial Hyperplasia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT14010 Gene_expression of SLC2A1 19 0.78 15.22 2.12 99.84
2 INT207233 Transcription of KRAS 3 0.48 1.56 0.03 99.84
3 INT146546 Gene_expression of MSI1 22 0.48 22.91 1.15 97.12
4 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57 96.96
5 INT89392 Negative_regulation of Positive_regulation of AKT1 23 0.50 15.69 3.02 95.28
6 INT182302 Negative_regulation of Localization of AKT1 5 0.39 3.52 0.06 95.28
7 INT135556 Localization of AKT1 38 0.69 12.78 1.17 94.88
8 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 94.20
9 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63 93.32
10 INT109975 Positive_regulation of Kras 14 0.45 12.72 1.68 91.80
11 INT6557 Gene_expression of Eno2 65 0.77 54.42 8.17 91.80
12 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73 90.76
13 INT192676 Binding of PTEN 14 0.46 10.58 3.06 88.76
14 INT179885 Regulation of PTEN 8 0.26 11.88 2.18 88.76
15 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19 77.40
16 INT304045 Transcription of PTEN 2 0.51 4.12 1.4 75.12
17 INT13654 Regulation of SLC2A1 1 0.44 0.44 0.68 75.00
18 INT136401 Binding of SLC2A1 2 0.36 1.75 0.22 75.00
19 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47 70.60
20 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97 70.08
21 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 69.00
22 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5 63.44
23 INT181744 Negative_regulation of Gene_expression of MLH1 3 0.05 7.67 0.12 56.40
24 INT107985 Gene_expression of MLH1 29 0.67 31.31 1.46 56.00
25 INT200666 Transcription of AKT1 8 0.66 4.23 0.2 55.32
26 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 46.64
27 INT38674 Regulation of KRT20 32 0.44 19 2.15 46.08
28 INT184985 Regulation of TFF3 2 0.26 1.43 0.07 45.72
29 INT185004 Positive_regulation of TFF3 4 0.47 3.77 0 45.72
30 INT304060 Positive_regulation of AGR2 2 0.70 13 0.63 45.48
31 INT304079 Regulation of AGR2 2 0.27 1.2 0 45.48
32 INT148882 Regulation of LTF 9 0.12 4.8 0.44 44.12
33 INT165516 Regulation of MSX2 8 0.23 3.41 0.09 44.12
34 INT219360 Regulation of MMP11 2 0.54 1.71 0.03 44.12
35 INT291934 Regulation of FOXA2 2 0.26 2.15 0 44.12
36 INT304051 Regulation of SCGB2A1 1 0.17 1.19 0 44.12
37 INT304068 Regulation of VPS11 1 0.12 1.24 0 44.12
38 INT304072 Positive_regulation of FOXA2 1 0.15 1.29 0 42.44
39 INT12089 Positive_regulation of MSX2 4 0.46 3.92 0.39 42.00
40 INT258435 Binding of Serpinb1c 3 0.24 2.43 0.07 41.76
41 INT172329 Binding of MRC1 8 0.36 3.88 0.03 39.68
42 INT292659 Positive_regulation of Gene_expression of FOLR1 2 0.47 1.59 0.14 38.68
43 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 38.28
44 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 38.28
45 INT25208 Gene_expression of IGF2 43 0.74 30.64 2.31 38.28
46 INT220206 Gene_expression of CCNB2 4 0.67 3.75 1.16 38.28
47 INT275575 Gene_expression of FOLR1 12 0.66 2.81 0.8 38.28
48 INT105948 Gene_expression of AURKA 5 0.65 4.26 0.03 38.28
49 INT304066 Gene_expression of BUB1 1 0.07 1.41 0 38.28
50 INT304075 Regulation of AURKA 1 0.15 1.38 0 36.60
51 INT304073 Regulation of CCNB2 1 0.10 1.39 0 36.60
52 INT304061 Regulation of BUB1 1 0.07 1.39 0 36.60
53 INT304074 Binding of MSH5 1 0.14 1.11 0 36.52
54 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 36.12
55 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 36.12
56 INT304071 Binding of MSH6 1 0.28 1.11 0 36.12
57 INT206139 Phosphorylation of KRT20 8 0.48 9.1 0.66 33.84
58 INT304078 Regulation of Phosphorylation of KRT20 1 0.00 1 0 33.84
59 INT176154 Gene_expression of PIK3CA 6 0.55 10.43 0.03 33.52
60 INT291365 Positive_regulation of Gene_expression of PIK3CA 2 0.41 5.76 0 33.52
61 INT305351 Positive_regulation of Regulation of FGFR2 2 0.37 0.97 0 32.48
62 INT207729 Regulation of FGFR2 4 0.22 2.35 0 32.48
63 INT105949 Positive_regulation of Gene_expression of AURKA 3 0.49 1.91 0.03 25.20
64 INT304052 Binding of MSI1 8 0.05 12.19 0 23.84
65 INT304058 Positive_regulation of MSI1 1 0.07 2.74 0 7.76
66 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
67 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
68 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 5.00
69 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 5.00
70 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
71 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
72 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 5.00
73 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 5.00
74 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
75 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 5.00
76 INT9292 Positive_regulation of SGCG 93 0.67 35.13 23.48 5.00
77 INT11157 Binding of EGF 88 0.48 53.73 21.25 5.00
78 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94 5.00
79 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 5.00
80 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 5.00
81 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 5.00
82 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 5.00
83 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 5.00
84 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 5.00
85 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36 5.00
86 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99 5.00
87 INT17565 Regulation of Gpt 85 0.60 43.64 13.68 5.00
88 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
89 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 5.00
90 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54 5.00
91 INT75137 Regulation of Akt1 74 0.48 37.89 9.7 5.00
92 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 5.00
93 INT108202 Positive_regulation of PIK3CG 47 0.67 25.83 8.25 5.00
94 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 5.00
95 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 5.00
96 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 5.00
97 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 5.00
98 INT92916 Gene_expression of Acta2 50 0.74 17.52 6.11 5.00
99 INT8106 Gene_expression of GGT1 31 0.75 18.65 6.1 5.00
100 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 5.00
101 INT105336 Regulation of AKT1 52 0.56 32.53 4.89 5.00
102 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86 5.00
103 INT56032 Positive_regulation of NCAM1 38 0.49 26.01 4.68 5.00
104 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 5.00
105 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45 5.00
106 INT109450 Positive_regulation of Phosphorylation of AKT1 62 0.64 25.18 4.21 5.00
107 INT86919 Negative_regulation of PIK3CG 40 0.57 21.16 3.97 5.00
108 INT151171 Positive_regulation of Pten 20 0.55 13.3 3.54 5.00
109 INT64766 Gene_expression of TWIST1 41 0.76 37.89 3.4 5.00
110 INT51607 Positive_regulation of DES 33 0.67 32.24 3.29 5.00
111 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21 5.00
112 INT200670 Gene_expression of AKT2 25 0.75 16.25 3 5.00
113 INT132760 Gene_expression of Pgr 47 0.66 28.17 2.85 5.00
114 INT184477 Negative_regulation of Pten 27 0.59 15.61 2.8 5.00
115 INT89397 Positive_regulation of PIK3CA 33 0.67 16.98 2.78 5.00
116 INT95164 Localization of NCAM1 13 0.78 6.06 2.62 5.00
117 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 5.00
118 INT74046 Localization of Calb2 12 0.80 2.05 2.24 5.00
119 INT107987 Gene_expression of MRC1 27 0.75 36.94 1.99 5.00
120 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98 5.00
121 INT12097 Regulation of GGT1 8 0.44 5.76 1.95 5.00
122 INT20421 Positive_regulation of MYC 19 0.67 10.43 1.9 5.00
123 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 5.00
124 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8 5.00
125 INT86909 Negative_regulation of MSH2 9 0.41 12.65 1.7 5.00
126 INT107992 Gene_expression of MSH2 39 0.78 37.09 1.6 5.00
127 INT94169 Negative_regulation of Phosphorylation of RB1 16 0.41 8.87 1.57 5.00
128 INT65684 Gene_expression of MDM2 30 0.62 24.94 1.55 5.00
129 INT11831 Positive_regulation of pid 13 0.40 23.37 1.54 5.00
130 INT76477 Positive_regulation of CD99 14 0.50 14.77 1.42 5.00
131 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41 5.00
132 INT92383 Gene_expression of KRAS 38 0.65 32.94 1.32 5.00
133 INT137382 Negative_regulation of Gene_expression of KRT20 22 0.58 12.29 1.29 5.00
134 INT139237 Negative_regulation of Gene_expression of CDH1 23 0.57 24.31 1.28 5.00
135 INT210399 Gene_expression of IGF2R 22 0.65 17.1 1.23 5.00
136 INT10117 Positive_regulation of INSR 10 0.43 4.71 1.22 5.00
137 INT190014 Regulation of Pten 8 0.62 6.03 1.2 5.00
138 INT119832 Positive_regulation of Gene_expression of PTEN 12 0.49 7.12 1.19 5.00
139 INT111605 Positive_regulation of CDH1 12 0.50 7.95 1.15 5.00
140 INT157765 Negative_regulation of CDH1 32 0.53 35.72 1.15 5.00
141 INT86908 Negative_regulation of MLH1 7 0.43 6.98 1.12 5.00
142 INT92139 Binding of MLH1 12 0.42 15.62 1 5.00
143 INT163280 Negative_regulation of Phosphorylation of CCND1 6 0.19 3.92 0.87 5.00
144 INT163289 Phosphorylation of CCND1 7 0.36 4.81 0.81 5.00
145 INT92142 Binding of MSH2 5 0.46 5.64 0.75 5.00
146 INT108204 Regulation of PIK3CG 9 0.12 4.16 0.75 5.00
147 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75 5.00
148 INT86370 Regulation of CDH1 10 0.54 13.89 0.7 5.00
149 INT37490 Negative_regulation of Cyp1b1 3 0.30 1.57 0.68 5.00
150 INT47038 Gene_expression of SFRP1 14 0.67 9.6 0.63 5.00
151 INT79432 Positive_regulation of Calb2 7 0.23 6.59 0.61 5.00
152 INT161322 Localization of PTEN 9 0.73 5.65 0.57 5.00
153 INT201846 Positive_regulation of SFRP4 4 0.37 2.74 0.54 5.00
154 INT146545 Negative_regulation of Gene_expression of MSH2 17 0.56 18.87 0.51 5.00
155 INT201858 Gene_expression of SFRP4 3 0.48 4.91 0.51 5.00
156 INT95328 Gene_expression of Gstp1 11 0.61 8.59 0.48 5.00
157 INT75001 Gene_expression of Cyp1b1 11 0.66 4.23 0.48 5.00
158 INT47030 Negative_regulation of ARMC9 22 0.38 13.08 0.47 5.00
159 INT175423 Positive_regulation of TSC1 25 0.36 21.81 0.45 5.00
160 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37 5.00
161 INT87406 Gene_expression of GSTP1 16 0.77 11.37 0.35 5.00
162 INT185886 Gene_expression of JUP 20 0.75 15.41 0.32 5.00
163 INT305348 Gene_expression of Peg3 2 0.25 2.36 0.31 5.00
164 INT85245 Positive_regulation of PID1 2 0.16 2.55 0.29 5.00
165 INT107983 Gene_expression of MSH6 6 0.51 5.57 0.27 5.00
166 INT120761 Positive_regulation of GSTP1 3 0.50 3.4 0.19 5.00
167 INT181920 Gene_expression of MSH3 2 0.50 2.54 0.18 5.00
168 INT206869 Gene_expression of ALDH1A2 3 0.38 2.51 0.16 5.00
169 INT134223 Localization of CD99 4 0.73 4.42 0.16 5.00
170 INT200671 Gene_expression of AKT3 4 0.69 1.88 0.13 5.00
171 INT250899 Gene_expression of Thbs2 17 0.75 4.97 0.13 5.00
172 INT206866 Positive_regulation of SFRP1 7 0.51 3.97 0.05 5.00
173 INT211581 Binding of Pms2 2 0.32 2.49 0.04 5.00
174 INT236108 Positive_regulation of Positive_regulation of Pten 3 0.39 2.3 0.04 5.00
175 INT190022 Positive_regulation of Mlh1 2 0.38 3.16 0.03 5.00
176 INT282953 Regulation of MSI1 2 0.03 1.63 0.03 5.00
177 INT304047 Positive_regulation of Transcription of TWIST1 1 0.10 0.57 0 5.00
178 INT304067 Positive_regulation of Transcription of GEMIN2 1 0.09 0.57 0 5.00
179 INT319140 Binding of ZIC2 1 0.36 1.24 0 5.00
180 INT304046 Positive_regulation of Transcription of SNAI2 1 0.49 0.57 0 5.00
181 INT304062 Regulation of Localization of PTEN 1 0.43 1.29 0 5.00
182 INT236621 Regulation of KRAS 7 0.53 6.16 0 5.00
183 INT304063 Positive_regulation of ALDH1A2 1 0.29 0.97 0 5.00
184 INT304059 Gene_expression of GEMIN2 1 0.12 0.66 0 5.00
185 INT198037 Regulation of PIK3CA 2 0.28 2.63 0 5.00
186 INT304050 Gene_expression of SUZ12 1 0.54 6.53 0 5.00
187 INT190053 Gene_expression of CASP5 3 0.45 2.46 0 5.00
188 INT190038 Binding of Mlh1 2 0.28 3.11 0 5.00
189 INT304076 Regulation of Localization of KRAS 2 0.36 2.39 0 5.00
190 INT305347 Negative_regulation of Gene_expression of Msh6 1 0.25 2.22 0 5.00
191 INT304049 Transcription of SNAI2 1 0.67 0.56 0 5.00
192 INT268686 Gene_expression of JAZF1 2 0.68 9.33 0 5.00
193 INT304065 Transcription of GEMIN2 1 0.12 0.57 0 5.00
194 INT190035 Binding of Msh6 2 0.28 2.72 0 5.00
195 INT180396 Localization of KRAS 3 0.69 2.89 0 5.00
196 INT304053 Gene_expression of KIAA1324 1 0.18 0.98 0 5.00
197 INT304064 Positive_regulation of KIAA1324 1 0.14 0.98 0 5.00
198 INT304048 Negative_regulation of Gene_expression of SFRP4 1 0.34 0.97 0 5.00
199 INT304057 Regulation of JAZF1 1 0.24 1 0 5.00
200 INT304070 Regulation of SUZ12 1 0.22 1 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox