D:Endometriosis (extended)

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Disease Term
Synonyms Adenocarcinoma Of The Endometrial, Adenocarcinoma Of The Endometrium, ADENOMA OF THE ENDOMETRIAL, Adenoma Of The Endometrium, Cancer Of The Endometrial, Cancer Of The Endometrium, Endometrial Adenocarcinoma, Endometrial Adenoma, Endometrial Cancer, Endometrial Hydration, ENDOMETRIAL HYPERPLASIA
Documents 4450
Hot Single Events 200
Hot Interactions 62

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Endometriosis (extended). They are ordered first by their relevance to Endometriosis (extended) and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT199971 IL6 Positive_regulation of ESR1 1 0.08 0.84 0.24 99.92
2 INT147755 Binding of GNRH1 and TNF 1 0.32 2.37 0.79 99.68
3 INT31182 Adra2a Regulation of Localization of Gh 1 0.01 0.35 0.32 99.00
4 INT324702 PLOD1 Positive_regulation of CGA 1 0.03 1.1 0.1 98.16
5 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25 97.64
6 INT3178 TSHR Positive_regulation of Prl 1 0.00 0.58 0.31 97.28
7 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73 97.16
8 INT324732 Positive_regulation of Binding of Prkaca and HR 1 0.00 1.12 0.08 97.04
9 INT213023 Hdl1 Regulation of Nos3 2 0.09 4.06 0.09 96.72
10 INT324731 Binding of Prkaca and HR 1 0.00 1.11 0.08 96.48
11 INT246413 TLR4 Regulation of TLR3 1 0.28 0.81 0.05 96.32
12 INT260565 T2dm2 Regulation of SUGT1 1 0.00 1.43 0.05 96.26
13 INT328932 TRGC1 Regulation of C2 1 0.03 0.92 0.31 96.24
14 INT68257 Binding of CALCA and GH1 1 0.00 0.54 0 96.08
15 INT68256 Binding of GH1 and SCT 1 0.04 0.54 0 96.08
16 INT164227 Binding of PAEP and Tnfrsf11b 1 0.00 1.18 0.77 95.96
17 INT109091 Tnf Positive_regulation of Localization of Il1b 1 0.56 1.08 0.36 95.60
18 INT152024 Ptgs1 Regulation of Fgf2 1 0.04 0.9 0.17 95.36
19 INT289765 Akt1 Regulation of Phosphorylation of Gsk3a 1 0.05 0.45 0.11 94.76
20 INT289768 Akt1 Regulation of Phosphorylation of Gsk3b 1 0.04 0.45 0.11 94.76
21 INT156057 UMOD Regulation of GABRG3 1 0.01 0.54 0.14 94.72
22 INT222466 Gnrh1 Regulation of Prl 1 0.14 1.16 0.07 93.96
23 INT65676 Binding of CGA and PLOD1 3 0.23 1.68 0.1 93.36
24 INT199976 EGF Regulation of ITGB3BP 1 0.02 0.77 0.57 92.60
25 INT199978 ESR1 Regulation of ITGB3BP 1 0.03 0.39 0.28 92.60
26 INT240620 Binding of INS and SHBG 4 0.12 3.35 0.15 92.36
27 INT291644 Binding of DST and ESR1 1 0.05 0.84 0.14 92.20
28 INT262223 Negative_regulation of Nr1i2 Negative_regulation of Gene_expression of CYP3A4 1 0.21 0.48 0 92.00
29 INT246414 TLR4 Regulation of Gene_expression of TLR3 1 0.35 1.16 0.17 91.88
30 INT171991 Binding of DMD and ERAL1 1 0.01 0.54 0 91.52
31 INT45782 Regulation of GNRH1 Positive_regulation of BRD2 1 0.06 0.16 0.61 91.48
32 INT45781 Regulation of GNRH1 Positive_regulation of PLOD1 1 0.06 0.16 0.61 91.48
33 INT45779 GNRH1 Positive_regulation of BRD2 1 0.07 0.16 0.6 91.48
34 INT45780 GNRH1 Positive_regulation of PLOD1 3 0.07 1.02 0.63 91.48
35 INT272731 Ptger2 Positive_regulation of Gene_expression of Ptgfr 1 0.01 0.65 0.25 91.20
36 INT272733 Binding of Ptger2 and Ptgfr 1 0.01 1.31 0.34 91.04
37 INT341777 SLC6A4 Regulation of EPHB1 1 0.02 0.96 0.3 90.60
38 INT222561 Gnrh1 Positive_regulation of Prl 1 0.15 0.38 0.22 90.24
39 INT189298 Atp6v1e1 Positive_regulation of Positive_regulation of Htr1a 1 0.00 1.15 0.11 89.60
40 INT1390 Trh Positive_regulation of Prl 14 0.67 4.42 4.39 89.44
41 INT262148 Positive_regulation of Nr1i2 Positive_regulation of Abcb1b 1 0.09 0.69 0.12 89.20
42 INT356086 Negative_regulation of Binding of App and Lrp1b 1 0.30 1.42 0.05 88.56
43 INT198934 Binding of App and Lrp1b 2 0.27 1.62 0.05 88.56
44 INT262226 Positive_regulation of Nr1i2 Positive_regulation of CYP3A4 1 0.17 0.68 0.12 88.48
45 INT189301 Atp6v1e1 Positive_regulation of Positive_regulation of Htr2a 1 0.01 1.13 0.11 88.24
46 INT199973 ESR1 Negative_regulation of EEF1B2P2 1 0.01 0.46 0.08 87.20
47 INT41006 GNRH1 Negative_regulation of Localization of CGA 1 0.03 0.87 0.3 87.12
48 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78 85.88
49 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38 85.88
50 INT240624 Binding of ADIPOQ and Hdl1 1 0.02 0.85 0.1 85.88
51 INT332305 Binding of CRP and Ccl2 1 0.15 0.86 0.06 85.80
52 INT291641 Binding of DST and ESRRG 1 0.16 1.8 0.28 84.40
53 INT198921 Binding of App and Lrp1 3 0.32 2.7 0.03 84.16
54 INT356102 Negative_regulation of Binding of App and Lrp1 1 0.32 0.71 0.03 84.16
55 INT138305 Binding of PNN and Agtr2 1 0.01 0.73 0.15 82.96
56 INT272755 Binding of DBI and Ptger2 1 0.00 1.13 0.33 82.76
57 INT270770 Binding of DMD and PTH 1 0.10 0.16 0 82.64
58 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32 82.44
59 INT199974 ESR1 Negative_regulation of Gene_expression of ITGB3BP 1 0.05 0.47 0.38 82.32
60 INT278579 Esr1 Positive_regulation of Negative_regulation of Tac2 1 0.47 0.25 0.03 82.28
61 INT240616 Binding of SHBG and ADIPOQ 1 0.31 4.43 0.37 80.68
62 INT224293 AR Positive_regulation of Protein_catabolism of ESR1 1 0.24 0.4 0.07 80.04
63 INT257590 Pth Positive_regulation of DMD 2 0.02 0.44 0 79.88
64 INT323152 Binding of DBT and ESR1 2 0.02 1.29 0.27 79.72
65 INT173936 Hrt1 Regulation of Gtf3a 1 0.00 1.16 0.44 79.56
66 INT272737 Positive_regulation of Binding of Ptger2 and Ptgfr 1 0.01 0.36 0.2 79.44
67 INT197651 TNF Regulation of PTH 1 0.05 1.67 0 79.04
68 INT197643 TNF Regulation of VDR 1 0.04 1.67 0 79.04
69 INT272727 Negative_regulation of Binding of Ptger2 and Ptgfr 1 0.01 0.36 0.1 79.00
70 INT186685 Edn1 Regulation of Gene_expression of Il6 1 0.11 1.1 0 78.72
71 INT312372 Binding of MME and TCHP 1 0.06 1.56 0 78.44
72 INT240626 Binding of ADIPOQ and Hdlcl1 1 0.02 3.27 0.28 77.92
73 INT138304 PNN Negative_regulation of Nr3c2 1 0.00 0.23 0 77.92
74 INT129868 Regulation of SERPINA6 Regulation of AVP 1 0.25 0.59 0.14 77.44
75 INT173946 Igf1 Regulation of Gene_expression of IGF1 1 0.08 0.68 0.21 76.32
76 INT173944 IGF1 Regulation of Gene_expression of Igf1 1 0.08 0.68 0.21 76.32
77 INT303967 Lep Positive_regulation of Gene_expression of Icam1 1 0.24 0.58 0.16 76.20
78 INT303999 Lep Positive_regulation of Gene_expression of ITGA2 1 0.06 0.29 0.08 76.20
79 INT303970 Lep Positive_regulation of Gene_expression of Itga2 1 0.09 0.29 0.08 76.20
80 INT231716 Binding of IL6 and DIP 1 0.24 1.55 0.87 76.16
81 INT138825 GNRH1 Regulation of Gene_expression of Oprm1 1 0.01 0.08 0 76.12
82 INT129869 SERPINA6 Regulation of AVP 1 0.25 2.33 0.54 75.96
83 INT65677 Binding of CGA and FSHR 2 0.25 0.29 0.16 75.96
84 INT12711 POMC Regulation of Prl 1 0.04 1.25 0.7 74.96
85 INT12710 Gnrhr Regulation of Prl 1 0.00 0.63 0.35 74.96
86 INT138826 GNRH1 Regulation of Oprm1 1 0.01 0.07 0 74.92
87 INT260563 Hdl1 Positive_regulation of Positive_regulation of Nos3 1 0.05 1.55 0 74.56
88 INT156056 AKR1C1 Negative_regulation of UMOD 1 0.03 0.41 0.1 73.92
89 INT329119 Binding of CNTN2 and CNTNAP2 1 0.08 2.41 0.73 73.60
90 INT272729 Ptger2 Positive_regulation of Ptgfr 1 0.01 0.3 0.17 72.68
91 INT180570 Binding of HEYL and Positive_regulation of DMD 1 0.00 1.08 0.28 70.44
92 INT173947 Il6 Positive_regulation of Gene_expression of IGF1 1 0.05 1.02 0.31 69.28
93 INT261262 AIS Negative_regulation of Cyp19a1 1 0.01 0.2 0.08 68.24
94 INT240622 Binding of ADIPOQ and Etv3 1 0.04 1.32 0.15 67.64
95 INT289766 Pgf Positive_regulation of Ptgfr 1 0.04 0.07 0.31 67.04
96 INT222299 Binding of CYP19A1 and AIS 2 0.25 1.65 0.31 66.60
97 INT184633 Binding of TRGC1 and PART1 1 0.03 0.19 0 66.52
98 INT184634 Binding of TRGC1 and TBATA 1 0.00 0.19 0 66.04
99 INT327198 DBT Positive_regulation of Gene_expression of ESRRA 1 0.00 0.42 0 65.16
100 INT328934 Binding of C2 and KIR2DS4 1 0.11 0.76 0.41 64.96
101 INT328933 Binding of KIR2DS4 and TRGC1 1 0.09 0.76 0.41 64.40
102 INT303997 IL1RL1 Positive_regulation of Lep 1 0.01 0.2 0.07 64.04
103 INT284892 AMH Regulation of Localization of FSHR 1 0.01 0.18 0 62.80
104 INT356095 Lrp1 Positive_regulation of App 1 0.37 0.53 0 62.64
105 INT233278 Binding of LBX1 and Tgif1 1 0.00 0.25 0.06 61.76
106 INT180564 HEYL Regulation of Regulation of DMD 1 0.00 0.88 0.28 61.68
107 INT328935 Binding of HLA-G and KIR2DS4 1 0.39 0.75 0.41 61.44
108 INT238826 Binding of INS and RBP4 1 0.10 2.07 0 60.96
109 INT284891 FSHR Positive_regulation of Gene_expression of PLOD1 2 0.03 1.32 0.11 60.24
110 INT356108 App Positive_regulation of Positive_regulation of Lrp1 1 0.43 0.52 0 60.24
111 INT356091 Lrp1 Positive_regulation of Positive_regulation of App 1 0.43 0.52 0 60.24
112 INT356104 Positive_regulation of Binding of App and Lrp1 1 0.40 0.52 0 60.24
113 INT309156 Esr1 Regulation of Gene_expression of Dlat 1 0.05 1.06 0.3 59.44
114 INT186249 Binding of ROS1 and SCN5A 1 0.09 0.73 0.03 59.12
115 INT199526 Ceacam1 Negative_regulation of Col1a1 1 0.01 0.06 0.03 58.96
116 INT199527 Ceacam1 Negative_regulation of CYP27A1 1 0.02 0.06 0.03 58.28
117 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29 56.56
118 INT318174 Binding of Crp and Xcl1 1 0.03 1.9 0.22 55.36
119 INT272388 Esr1 Regulation of Transcription of Trpv6 1 0.03 0.13 0.06 54.16
120 INT321642 Binding of Cd3e and Spn 1 0.00 1.08 0 54.16
121 INT201445 ESR1 Regulation of Slc6a3 1 0.02 0.05 0.04 53.92
122 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07 52.16
123 INT19633 GNRH1 Regulation of Localization of CGA 4 0.44 0.82 1.33 51.72
124 INT172568 Gene_expression of GNRH1 Regulation of Localization of CGA 1 0.05 0.66 0.08 51.72
125 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27 51.68
126 INT324705 CGA Positive_regulation of PLOD1 1 0.04 0 0 50.00
127 INT324704 PLOD1 Positive_regulation of HRASLS 1 0.05 0 0 50.00
128 INT324706 CGA Positive_regulation of HRASLS 1 0.01 0 0 50.00
129 INT122838 Mdh1 Positive_regulation of Tst 1 0.78 0.4 0.55 49.16
130 INT233279 Binding of TLX1 and Tgif1 1 0.00 0.05 0 48.96
131 INT309158 Binding of Esr1 and Dlat 1 0.04 1.39 0.61 48.48
132 INT189303 Atp6v1e1 Positive_regulation of Gene_expression of TPH1 1 0.01 0.16 0.73 48.36
133 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 47.52
134 INT210597 Negative_regulation of Binding of TNFSF11 and TNFRSF11A 3 0.26 5.66 0.33 47.52
135 INT350106 Binding of SLC4A3 and SLC4A1 1 0.13 2.78 0.09 46.96
136 INT266383 Binding of Ager and S100b 1 0.01 3.48 0.33 45.12
137 INT147936 CGA Regulation of Gene_expression of FSHR 1 0.31 0.71 0.1 43.72
138 INT309129 Dlat Positive_regulation of Gene_expression of Btg1 1 0.00 1.05 0.42 43.52
139 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42 43.52
140 INT198926 Binding of Apbb1 and Lrp1 5 0.12 2.18 0.24 42.64
141 INT356117 Binding of SORL1 and Apbb1 1 0.14 0.43 0 42.64
142 INT356100 Binding of Apbb1 and App 1 0.14 0.43 0 42.64
143 INT176569 Binding of FSHR and Cyp19a1 1 0.04 0.06 0 41.72
144 INT356118 Binding of SORL1 and App 1 0.41 0.43 0 41.60
145 INT323840 Binding of Esr1 and Il1 1 0.04 0.9 0.42 40.56
146 INT238827 RBP4 Positive_regulation of Gene_expression of INS 1 0.14 1.15 0 40.24
147 INT270775 PTH Regulation of DMD 1 0.09 0.64 0.03 40.12
148 INT63391 SLTM Regulation of Gene_expression of Col2a1 1 0.00 0 0 39.72
149 INT289763 Ptgfr Positive_regulation of Gene_expression of Sat1 1 0.04 0 0.04 39.36
150 INT174503 Binding of HLA-B and KIR3DL1 6 0.37 3.48 1.61 39.12
151 INT236591 Binding of Esr1 and Positive_regulation of Tmed4 1 0.04 0.52 0.05 39.12
152 INT289762 Pgf Positive_regulation of Gene_expression of Sat1 1 0.21 0 0.04 38.40
153 INT60536 Gnrh1 Positive_regulation of Localization of Prl 2 0.22 1.12 0.6 38.28
154 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5 38.08
155 INT328936 Binding of HLA-B and KIR3DS1 1 0.25 0.7 0.48 37.92
156 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41 37.80
157 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42 37.68
158 INT266384 Binding of Ager and S100a6 1 0.01 1.32 0.11 37.48
159 INT266415 Binding of ROS1 and S100a6 1 0.02 0.82 0.03 37.48
160 INT260600 Binding of Ppargc1a and Siglec1 1 0.14 1.25 0 36.24
161 INT289767 Ptgfr Positive_regulation of Positive_regulation of Pgf 1 0.03 0 0.05 36.16
162 INT257577 CALCA Positive_regulation of DMD 1 0.01 0.57 0.26 35.92
163 INT173949 Binding of IGF1 and Atp6v1e1 1 0.01 0.89 0.28 35.20
164 INT301178 UCP2 Negative_regulation of ROS1 1 0.29 1.41 0 34.80
165 INT186248 NR5A1 Positive_regulation of Transcription of STAR 1 0.01 0.21 0 34.28
166 INT291554 Binding of ESR1 and St8sia2 1 0.01 0.49 0.33 34.24
167 INT173948 Gh Positive_regulation of Gene_expression of IGF1 2 0.36 0.77 0.1 32.72
168 INT199975 ESR1 Positive_regulation of PGR 1 0.05 0.11 0 32.56
169 INT264297 Binding of IGF1 and NOL3 1 0.36 0.44 0 32.40
170 INT180560 Binding of COMP and CYP27A1 1 0.12 0.47 0.18 32.20
171 INT148531 Binding of TNFRSF11A and Tnfsf11 2 0.08 1.77 0.17 31.96
172 INT272416 PROK1 Positive_regulation of Gene_expression of VEGFA 1 0.26 0 0 31.44
173 INT287268 Binding of ERBB2 and ERBB3 5 0.16 2.74 0 30.16
174 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95 30.08
175 INT278572 Atp6v1e1 Negative_regulation of Gene_expression of Tacr3 1 0.22 0 0.03 30.08
176 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 29.44
177 INT309136 Dlat Positive_regulation of Gene_expression of Car1 1 0.03 0.99 0.45 29.08
178 INT183614 Binding of ESR1 and TMED4 2 0.02 0.13 0.03 29.08
179 INT188803 Il1 Positive_regulation of Gene_expression of Crp 1 0.03 2.95 0.94 28.96
180 INT356114 Prkca Positive_regulation of Binding of App and Tg 1 0.02 0.12 0.26 28.72
181 INT329479 Binding of TNFRSF11B and TNF 1 0.04 0.71 0 28.64
182 INT25400 Binding of Ptger1 and Ptger2 2 0.11 1.02 0.15 28.44
183 INT234755 IL10 Positive_regulation of IFN1@ 1 0.08 0.68 0.23 28.20
184 INT356094 Binding of App and Tg 1 0.08 0.12 0.26 28.00
185 INT44441 GNRH1 Positive_regulation of Localization of FSHR 2 0.15 0.86 0.26 26.80
186 INT270758 GNRHR Positive_regulation of Localization of FSHR 1 0.08 0.68 0 26.80
187 INT266080 Binding of PAPPA and MUC16 1 0.40 0.74 0 26.68
188 INT329480 Binding of TNFRSF11B and TNFSF10 1 0.03 0.71 0 26.32
189 INT266068 Binding of CHKB and MUC16 1 0.22 0.74 0 25.76
190 INT173937 Hrt1 Regulation of Il1 1 0.00 0.28 0.13 25.32
191 INT27775 Binding of LH and Tst 1 0.25 0 0.93 25.00
192 INT100265 Hsp90aa1 Regulation of Positive_regulation of Esrrb 1 0.10 0.1 0 25.00
193 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07 23.88
194 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 23.48
195 INT279799 ATP6V0A2 Regulation of ERBB3 1 0.00 1.77 0.12 19.84
196 INT279804 ATP6V0A2 Regulation of MCF2 1 0.00 1.76 0.12 19.84
197 INT278573 Atp6v1e1 Regulation of Gene_expression of Tacr3 1 0.17 0.07 0.09 19.12
198 INT278577 Atp6v1e1 Regulation of Gene_expression of Tac2 1 0.16 0.07 0 19.12
199 INT291543 Binding of Dlat and Gper 1 0.15 0.37 0.33 18.24
200 INT266412 Binding of S100A12 and Ager 1 0.01 1.03 0.15 18.16

Single Events

The table below shows the top 200 pain related interactions that have been reported for Endometriosis (extended). They are ordered first by their pain relevance and then by number of times they were reported in Endometriosis (extended). Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54 100.00
2 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 100.00
3 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 100.00
4 INT4145 Gene_expression of FSHR 124 0.77 44.98 13.04 100.00
5 INT1792 Positive_regulation of CGA 123 0.70 64.73 20.79 100.00
6 INT40712 Gene_expression of EPX 9 0.78 5.93 3.6 100.00
7 INT67488 Binding of Pc 8 0.31 4.6 1.13 100.00
8 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71 100.00
9 INT111161 Positive_regulation of EFNA1 6 0.40 4.62 0.68 100.00
10 INT7972 Positive_regulation of Gene_expression of PLOD1 15 0.42 5.73 1.96 100.00
11 INT111155 Positive_regulation of G0s2 9 0.46 9.54 1.53 100.00
12 INT71418 Binding of CES1 42 0.40 29.78 5.01 100.00
13 INT324721 Binding of GTS 1 0.16 0.99 0 100.00
14 INT181282 Transcription of INCENP 10 0.11 1.21 0.66 100.00
15 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 100.00
16 INT1578 Negative_regulation of Localization of PRL 52 0.59 20.62 17.18 100.00
17 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 100.00
18 INT2982 Positive_regulation of Gene_expression of CGA 17 0.59 9.08 1.99 100.00
19 INT189284 Positive_regulation of Negative_regulation of Atp6v1e1 2 0.20 1.82 0.28 100.00
20 INT44979 Positive_regulation of Pnp 11 0.59 5.61 2.41 100.00
21 INT50440 Negative_regulation of Pnp 5 0.36 2.14 0.66 100.00
22 INT111154 Negative_regulation of G0s2 1 0.01 0.79 0.28 100.00
23 INT2836 Positive_regulation of PAEP 51 0.67 26.69 4.57 100.00
24 INT111153 Positive_regulation of Dkk1 13 0.68 10.56 2.58 100.00
25 INT3811 Negative_regulation of PAEP 36 0.50 23.7 5.18 100.00
26 INT111156 Negative_regulation of Dkk1 21 0.58 20.08 4.27 100.00
27 INT111162 Negative_regulation of EFNA1 2 0.03 2.78 1.45 100.00
28 INT93886 Positive_regulation of Gene_expression of PGR 19 0.52 15.78 1.89 100.00
29 INT165659 Positive_regulation of Gene_expression of Pak1 1 0.69 2.19 2.19 100.00
30 INT11889 Regulation of Gene_expression of MUC16 5 0.62 3.24 0.63 100.00
31 INT159777 Regulation of Negative_regulation of Shbg 2 0.41 1.54 0.36 100.00
32 INT136982 Positive_regulation of Positive_regulation of Nr1i2 3 0.65 4.66 2.89 100.00
33 INT45899 Regulation of Localization of LGR6 3 0.27 1.85 0.64 100.00
34 INT251079 Gene_expression of G0s2 32 0.77 36.32 2.01 100.00
35 INT282576 Negative_regulation of Gene_expression of POU5F1 12 0.43 2.79 0.16 100.00
36 INT29561 Binding of GSTM1 35 0.48 25.86 6.24 100.00
37 INT19409 Binding of Cyp1a1 12 0.48 2.58 1.97 100.00
38 INT93885 Positive_regulation of Gene_expression of MKI67 8 0.60 4.4 0.18 100.00
39 INT16235 Positive_regulation of CGB 27 0.70 15.71 4.06 100.00
40 INT119520 Gene_expression of TXK 19 0.19 17.54 1.45 100.00
41 INT4771 Gene_expression of CGB 23 0.67 14.22 3.42 100.00
42 INT45860 Positive_regulation of Binding of Ptgfr 3 0.49 1.8 2.22 100.00
43 INT103824 Positive_regulation of SOD2 26 0.70 17.42 7.17 100.00
44 INT4632 Regulation of CGB 9 0.38 1.81 3.53 100.00
45 INT77852 Binding of Chd7 8 0.31 4.1 2.51 100.00
46 INT205618 Gene_expression of Renbp 15 0.26 9.26 1.04 100.00
47 INT251078 Positive_regulation of Gene_expression of G0s2 8 0.69 8.1 0.57 100.00
48 INT230634 Negative_regulation of POU5F1 10 0.43 1.03 0.46 100.00
49 INT189290 Positive_regulation of Positive_regulation of Htr2a 1 0.02 2.51 1.41 99.98
50 INT171998 Binding of DMD 58 0.47 38.13 3.35 99.98
51 INT45901 Localization of LGR6 5 0.80 2.48 1.64 99.98
52 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33 99.96
53 INT15054 Gene_expression of Mme 48 0.77 42.52 10.63 99.96
54 INT11230 Regulation of MUC16 23 0.60 19.54 3.93 99.96
55 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 99.96
56 INT68813 Transcription of Oprm1 93 0.71 20.11 57.65 99.96
57 INT186797 Localization of TLR3 2 0.70 2.69 0.12 99.96
58 INT23010 Positive_regulation of CYP19A1 28 0.58 24.18 5.37 99.96
59 INT62895 Gene_expression of NOSTRIN 51 0.75 28.8 10.68 99.92
60 INT141612 Gene_expression of Ccr1 92 0.77 72.09 24.14 99.90
61 INT238464 Gene_expression of SOCS6 2 0.22 1.15 0.03 99.90
62 INT15887 Gene_expression of Nbr1 39 0.77 23.91 7.34 99.88
63 INT14010 Gene_expression of SLC2A1 19 0.78 15.22 2.12 99.88
64 INT136401 Binding of SLC2A1 2 0.36 1.75 0.22 99.88
65 INT55597 Negative_regulation of Gpx1 59 0.55 28.3 8.83 99.88
66 INT98057 Regulation of Htr2a 9 0.44 5.06 4.28 99.86
67 INT136772 Positive_regulation of Trpv6 2 0.70 0.61 0.36 99.86
68 INT3057 Gene_expression of Ptgfr 60 0.58 14.54 11.73 99.84
69 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19 99.84
70 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 99.84
71 INT425 Localization of PRL 455 0.81 189.64 144.8 99.84
72 INT31333 Gene_expression of Esr2 19 0.69 8.78 6.83 99.84
73 INT121943 Positive_regulation of Nr1i2 64 0.68 19.22 8.39 99.84
74 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15 99.84
75 INT92139 Binding of MLH1 12 0.42 15.62 1 99.84
76 INT162109 Negative_regulation of Gene_expression of Esr1 4 0.16 2.41 0.12 99.84
77 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 99.84
78 INT164291 Regulation of Positive_regulation of SCN5A 2 0.38 0.73 0.15 99.84
79 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46 99.84
80 INT262127 Negative_regulation of Gene_expression of Nr1i2 1 0.55 6.92 1.57 99.84
81 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 99.84
82 INT108799 Regulation of Gene_expression of ALPP 9 0.27 2.98 0.62 99.84
83 INT94887 Regulation of Gene_expression of PTGFR 2 0.20 0.23 0.18 99.84
84 INT5135 Negative_regulation of GNRH1 106 0.58 36.63 27.71 99.82
85 INT185519 Binding of Vms1 5 0.12 4.58 1.37 99.82
86 INT96871 Regulation of Transcription of AHR 2 0.41 0.46 0.33 99.82
87 INT96874 Regulation of Transcription of ARNT 1 0.29 0.38 0.18 99.82
88 INT96875 Regulation of Gene_expression of AHR 1 0.25 0.38 0.18 99.82
89 INT229200 Gene_expression of Pc 13 0.65 8.96 2.32 99.80
90 INT7975 Regulation of PLOD1 97 0.62 20.9 30.51 99.80
91 INT35835 Positive_regulation of Htr2a 17 0.67 10.68 9.81 99.80
92 INT7035 Regulation of CGA 87 0.45 29.04 28.45 99.80
93 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 99.78
94 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69 99.78
95 INT2261 Gene_expression of Lhb 121 0.77 42.78 26.04 99.76
96 INT142284 Gene_expression of Hrt1 2 0.13 4.77 0.34 99.76
97 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 99.76
98 INT38989 Gene_expression of IDUA 22 0.78 16.99 1.26 99.76
99 INT185520 Regulation of Binding of Vms1 2 0.09 0.86 0.57 99.76
100 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 99.74
101 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03 99.74
102 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9 99.74
103 INT176586 Positive_regulation of Binding of ESR1 11 0.41 4.64 0.33 99.74
104 INT174728 Positive_regulation of Transcription of ESR1 10 0.47 3.3 0.83 99.74
105 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68 99.72
106 INT127767 Negative_regulation of Atp6v1e1 9 0.23 5.66 1.52 99.72
107 INT12339 Localization of IL8 437 0.81 251.87 117.39 99.72
108 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.72
109 INT1425 Gene_expression of Rbm39 143 0.58 51.32 65.44 99.72
110 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 99.72
111 INT5320 Gene_expression of PTGFR 18 0.59 12.99 3.7 99.72
112 INT48222 Positive_regulation of Localization of IL8 123 0.59 78.04 37.2 99.72
113 INT130866 Positive_regulation of Gene_expression of TNFSF11 25 0.69 7.11 1.82 99.72
114 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 99.70
115 INT15849 Gene_expression of FRTS 27 0.58 7.14 5.14 99.70
116 INT187038 Regulation of Gene_expression of FRTS 1 0.39 1.05 0 99.70
117 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 99.68
118 INT154527 Gene_expression of POU5F1 180 0.78 34.01 4.34 99.68
119 INT7234 Binding of GNRH1 43 0.47 21.59 12.36 99.68
120 INT282590 Positive_regulation of Gene_expression of POU5F1 40 0.70 8.42 1.32 99.68
121 INT51279 Regulation of IGFBP3 17 0.49 15.89 2.45 99.68
122 INT32431 Gene_expression of HTC2 17 0.75 9.72 1.93 99.68
123 INT6481 Binding of TNF 624 0.48 510.2 214.82 99.68
124 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37 99.68
125 INT294995 Binding of Use1 2 0.02 1.43 0.11 99.68
126 INT18440 Binding of GGT5 1 0.31 0.18 0.21 99.66
127 INT26538 Positive_regulation of FSHR 103 0.69 30.95 15.33 99.64
128 INT920 Localization of PLOD1 223 0.81 42.25 78.7 99.64
129 INT913 Regulation of Localization of PLOD1 71 0.62 8.64 32.72 99.64
130 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 99.64
131 INT32256 Gene_expression of PLXNA3 11 0.75 7.8 4.92 99.64
132 INT26860 Positive_regulation of Vms1 7 0.41 3.21 1.18 99.62
133 INT96881 Gene_expression of ARNT 8 0.50 3.27 1.98 99.60
134 INT96876 Gene_expression of AHR 20 0.77 10.43 2.39 99.60
135 INT2262 Negative_regulation of Lhb 142 0.59 25.47 44.81 99.60
136 INT97797 Localization of TLR4 18 0.77 13.78 6 99.60
137 INT96877 Transcription of AHR 7 0.62 3.25 1.77 99.60
138 INT103806 Negative_regulation of Aaiq4 4 0.41 3.72 0.31 99.60
139 INT96870 Transcription of ARNT 1 0.44 0.81 0.4 99.60
140 INT19844 Negative_regulation of Gene_expression of Lhb 12 0.51 3.19 2.97 99.60
141 INT108306 Positive_regulation of TNFRSF11B 28 0.60 12.74 4.46 99.60
142 INT108250 Regulation of Prdx2 5 0.25 2.02 2.08 99.60
143 INT209893 Positive_regulation of Gene_expression of TNFRSF11B 31 0.68 11.77 4.8 99.60
144 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 99.58
145 INT22129 Positive_regulation of Gene_expression of CAT 11 0.67 4.23 2.37 99.58
146 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.56
147 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 99.56
148 INT55743 Gene_expression of Timp2 25 0.31 8.95 4.3 99.56
149 INT86361 Positive_regulation of Positive_regulation of NOS1 39 0.53 18.93 10.42 99.56
150 INT119991 Regulation of MROS 5 0.23 4.75 0.48 99.56
151 INT149818 Gene_expression of Clock 81 0.70 14.15 10.04 99.56
152 INT120109 Negative_regulation of Timp2 8 0.33 3.28 2.23 99.56
153 INT64777 Negative_regulation of COL5A2 32 0.38 17.4 2.28 99.56
154 INT132575 Binding of NR1H4 57 0.20 22.06 2.82 99.56
155 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 99.56
156 INT142184 Regulation of TXK 10 0.11 8.25 0.59 99.56
157 INT462 Regulation of Pomc 157 0.62 41.67 67.27 99.56
158 INT177318 Negative_regulation of Binding of NR1H4 5 0.14 3.39 0.08 99.56
159 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 99.54
160 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21 99.54
161 INT9783 Gene_expression of INSRR 81 0.50 32.99 15.52 99.54
162 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 99.54
163 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 99.54
164 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 99.54
165 INT187721 Transcription of PLOD1 4 0.49 4.69 0.51 99.52
166 INT324723 Transcription of CGA 1 0.07 4.35 0.15 99.52
167 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 99.52
168 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22 99.52
169 INT22798 Regulation of Shbg 64 0.60 26.71 8.76 99.52
170 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17 99.52
171 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 99.52
172 INT45675 Regulation of Gene_expression of Shbg 6 0.15 4.65 1.03 99.52
173 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 99.52
174 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 99.52
175 INT919 Regulation of Positive_regulation of GH1 7 0.47 1.09 2.75 99.52
176 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18 99.48
177 INT123701 Negative_regulation of VDR 61 0.59 48.94 9.67 99.46
178 INT14886 Positive_regulation of TAC3 3 0.49 0.42 0.24 99.46
179 INT14884 Positive_regulation of Gene_expression of SFTPA1 32 0.25 20.37 26.09 99.46
180 INT8836 Positive_regulation of SFTPA1 36 0.47 28.37 23.59 99.46
181 INT14885 Positive_regulation of Gene_expression of TAC3 2 0.67 0.74 0.39 99.46
182 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.44
183 INT65284 Regulation of Pc 7 0.52 5.93 2.24 99.42
184 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 99.40
185 INT15888 Positive_regulation of Nbr1 42 0.69 35.76 10.48 99.40
186 INT2630 Positive_regulation of Shbg 134 0.70 65.26 15.19 99.40
187 INT8531 Transcription of PDYN 56 0.72 19.51 30.99 99.40
188 INT37005 Regulation of Nbr1 6 0.24 6.33 1.56 99.40
189 INT282599 Regulation of Gene_expression of POU5F1 10 0.62 4.89 0.71 99.40
190 INT89484 Gene_expression of TNFRSF11B 119 0.76 53.57 19.67 99.40
191 INT952 Negative_regulation of GHRH 57 0.56 25.3 10.34 99.40
192 INT143159 Regulation of Gene_expression of TLR4 28 0.62 15.08 3.54 99.40
193 INT145768 Regulation of TLR4 19 0.45 8.31 2.96 99.40
194 INT186798 Regulation of TLR3 5 0.42 3.13 0.69 99.40
195 INT246420 Regulation of Gene_expression of TLR3 1 0.57 0.79 0.11 99.40
196 INT20462 Binding of ESR1 210 0.44 102.7 26.34 99.38
197 INT246423 Negative_regulation of TLR3 1 0.40 2.2 0.6 99.38
198 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25 99.38
199 INT204525 Negative_regulation of Gene_expression of TLR3 2 0.54 1.8 0.61 99.38
200 INT108796 Binding of ESR2 5 0.46 6.84 2.36 99.38
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