D:Endophthalmitis

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Disease Term
Synonyms Endophthalmitides, OPHTHALMIA, OPHTHALMIAS
Documents 264
Hot Single Events 49
Hot Interactions 4

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Endophthalmitis. They are ordered first by their relevance to Endophthalmitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43 92.56
2 INT285077 CCL16 Positive_regulation of ITK 1 0.05 1.95 0.31 91.20
3 INT285076 CCL16 Positive_regulation of Gene_expression of ITK 1 0.05 1.8 0.14 91.20
4 INT19922 Binding of F13A1 and Plat 1 0.01 0.46 0.1 85.24
5 INT273770 VEGFA Negative_regulation of Localization of Twist1 1 0.07 0.58 0 64.00
6 INT285068 ITK Regulation of CCL16 1 0.02 1.86 0.03 49.84
7 INT285067 Negative_regulation of ITK Regulation of CCL16 1 0.04 1.1 0.03 49.84
8 INT209581 Twist1 Positive_regulation of Gene_expression of VEGFA 6 0.06 7.86 0.16 33.84
9 INT260529 Twist1 Positive_regulation of Gene_expression of Vegfa 1 0.04 0.54 0 33.36
10 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
11 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73 5.00
12 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73 5.00
13 INT252646 Binding of C6orf25 and SYT16 1 0.00 0.51 0.17 5.00
14 INT288026 PROC Positive_regulation of Gene_expression of VEGFA 1 0.01 0.5 0.15 5.00
15 INT285070 CCL16 Positive_regulation of Gene_expression of CYP19A1 1 0.02 0.69 0.09 5.00
16 INT353105 Binding of Aes and Rgs9bp 1 0.01 0.35 0.05 5.00
17 INT284705 CMA1 Positive_regulation of Gene_expression of COL7A1 1 0.04 0.49 0.05 5.00
18 INT288025 VEGFA Regulation of IL6 1 0.36 0.26 0.03 5.00
19 INT288027 VEGFA Regulation of CCL2 1 0.44 0.26 0.03 5.00
20 INT288028 VEGFA Regulation of IL8 1 0.36 0.26 0.03 5.00
21 INT353104 Binding of amd and Gtf3a 1 0.01 1.53 0.03 5.00
22 INT346947 Binding of VEGFA and amd 1 0.01 0.1 0 5.00
23 INT285071 EGF Positive_regulation of CCL16 1 0.03 0.77 0 5.00
24 INT353106 Binding of amd and C3 1 0.09 1.69 0 5.00
25 INT353108 Binding of VEGFA and Pgf 1 0.02 2.17 0 5.00
26 INT285074 Positive_regulation of ITK Regulation of CCL16 1 0.04 0.77 0 5.00
27 INT353107 Binding of VEGFA and Vegfb 1 0.02 1.08 0 5.00
28 INT353110 Binding of VEGFA and Eo 1 0.00 0.67 0 5.00
29 INT285072 EGF Positive_regulation of ITK 1 0.03 0.77 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Endophthalmitis. They are ordered first by their pain relevance and then by number of times they were reported in Endophthalmitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT130149 Binding of Bre 3 0.26 0.64 0.19 100.00
2 INT215107 Gene_expression of Spir1 17 0.50 10.38 0.25 98.96
3 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34 98.84
4 INT256902 Positive_regulation of TNMD 3 0.44 5.27 0.13 98.62
5 INT252662 Binding of SYT16 1 0.01 8.05 0.45 98.52
6 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 98.50
7 INT96269 Positive_regulation of Mcpt1 71 0.61 52.38 20.4 98.48
8 INT125733 Positive_regulation of Positive_regulation of Mcpt1 6 0.44 3.79 1.38 98.48
9 INT9020 Binding of Tsv 2 0.25 1.28 0.48 98.24
10 INT168257 Binding of MLL 4 0.02 4.25 0.53 98.00
11 INT10874 Negative_regulation of Twist1 89 0.50 36.84 11.32 96.88
12 INT11679 Negative_regulation of F13A1 55 0.54 33.69 9.43 96.38
13 INT17182 Binding of Cea 25 0.48 14.98 4.16 96.04
14 INT209355 Binding of SLC9A6 8 0.42 14.9 0.09 95.78
15 INT346642 Positive_regulation of Positive_regulation of TNMD 1 0.44 1.28 0 95.78
16 INT94028 Regulation of Twist1 37 0.44 22.41 5.33 95.08
17 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 95.00
18 INT253218 Negative_regulation of Binding of Mapk1ip1 1 0.37 0.28 0 94.64
19 INT260525 Gene_expression of AMD1 25 0.66 24.58 1.32 94.32
20 INT4535 Localization of PROC 106 0.73 76.24 21.1 93.84
21 INT276437 Binding of Spir1 4 0.12 6.56 0 93.56
22 INT61519 Gene_expression of Mpo 112 0.78 89.29 18.22 92.48
23 INT239498 Localization of Aes 2 0.58 2.22 0.4 92.44
24 INT256900 Gene_expression of TNMD 19 0.68 7.36 0.64 92.36
25 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 92.24
26 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 92.12
27 INT253219 Binding of Mapk1ip1 1 0.32 0.28 0 91.48
28 INT267894 Gene_expression of ITK 13 0.57 9.71 0.9 90.24
29 INT1981 Negative_regulation of NARFL 219 0.47 223.48 16.41 89.88
30 INT65033 Negative_regulation of Fgf2 21 0.59 12.36 2.94 89.20
31 INT285097 Negative_regulation of CCL16 3 0.13 3.88 0.24 88.88
32 INT109470 Negative_regulation of ITK 3 0.24 2.13 0.96 88.88
33 INT43820 Positive_regulation of Twist1 75 0.59 42.15 8.47 88.64
34 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 88.60
35 INT150851 Positive_regulation of Cxcl1 45 0.57 20.83 11.88 88.52
36 INT109910 Gene_expression of CCL16 104 0.74 76.1 43.97 88.36
37 INT116540 Binding of Twist1 35 0.48 16.32 2.85 87.12
38 INT285094 Binding of ITK 4 0.11 2.14 0.05 85.80
39 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 85.12
40 INT272274 Localization of NARFL 24 0.60 27.55 1.18 84.96
41 INT217429 Positive_regulation of SLC9A6 22 0.38 42.17 0.67 84.56
42 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 84.48
43 INT164966 Binding of Cle 2 0.32 0.91 0.19 83.04
44 INT58301 Positive_regulation of Mpo 87 0.70 80.19 23.99 81.68
45 INT127378 Localization of Mpo 21 0.78 26.36 8.28 81.68
46 INT81226 Gene_expression of Adk 9 0.64 9.28 4.81 81.44
47 INT272415 Negative_regulation of Gene_expression of NARFL 14 0.34 17.62 0.73 81.12
48 INT272273 Gene_expression of NARFL 89 0.54 121.19 4.47 80.64
49 INT223959 Localization of Bglap 10 0.77 11.25 1.74 80.36
50 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 78.76
51 INT8775 Binding of IGHE 167 0.48 102.61 23.54 76.20
52 INT10873 Localization of Twist1 21 0.74 10.43 1.37 75.52
53 INT283301 Positive_regulation of Localization of Mpo 2 0.44 2.38 0.54 73.56
54 INT109917 Positive_regulation of Gene_expression of CCL16 17 0.66 11.87 2.94 69.92
55 INT208589 Negative_regulation of Gene_expression of CCL16 3 0.40 2.1 0.52 69.64
56 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 69.24
57 INT16214 Localization of F13A1 36 0.74 21.8 4.87 68.52
58 INT273160 Binding of TNMD 4 0.42 1.72 0 67.36
59 INT58302 Regulation of Mpo 13 0.62 11.14 3.04 67.28
60 INT110768 Transcription of Mcpt1 12 0.52 7.66 4.71 65.84
61 INT283299 Transcription of Serpina1a 2 0.17 1.28 0.18 65.84
62 INT297602 Positive_regulation of Tsv 3 0.07 3.36 0.33 65.04
63 INT11109 Positive_regulation of Serpina1a 5 0.68 4.97 1.12 64.80
64 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17 62.92
65 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 59.60
66 INT10171 Binding of Gtf3a 33 0.36 19.84 5.1 59.60
67 INT285095 Regulation of GSPT1 1 0.00 0.83 0.03 59.16
68 INT192975 Localization of SLC9A6 7 0.43 14.24 0.24 57.64
69 INT165630 Positive_regulation of Regulation of Mpo 2 0.39 1.49 0.42 57.36
70 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 56.24
71 INT219579 Negative_regulation of Gene_expression of Twist1 12 0.43 9.07 1.36 54.56
72 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 51.28
73 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 50.96
74 INT112717 Negative_regulation of Binding of VEGFA 21 0.56 11.07 0.99 46.16
75 INT139862 Negative_regulation of amd 8 0.35 10.15 0.6 45.44
76 INT107593 Regulation of Ecd 2 0.21 1.16 0.23 38.32
77 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75 37.36
78 INT346946 Regulation of Negative_regulation of amd 1 0.05 0.57 0.3 36.40
79 INT202939 Regulation of AMD1 4 0.38 2.68 0 34.92
80 INT272414 Positive_regulation of Positive_regulation of NARFL 9 0.37 12.88 0.84 34.28
81 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63 33.36
82 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 32.04
83 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 31.64
84 INT231199 Positive_regulation of Localization of Twist1 3 0.50 1.45 0.38 31.64
85 INT311459 Negative_regulation of Cle 1 0.20 0.3 0 30.72
86 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54 30.36
87 INT184301 Negative_regulation of Bglap 16 0.56 11.22 1.22 30.04
88 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25 28.72
89 INT68299 Binding of Tnf 17 0.39 12.55 7.49 27.60
90 INT291575 Negative_regulation of Gene_expression of Adk 1 0.32 1.05 0.03 26.88
91 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 26.32
92 INT224722 Binding of Mcpt1 6 0.10 4.82 1.03 24.96
93 INT209354 Gene_expression of SLC9A6 15 0.58 37.52 0.29 24.88
94 INT217428 Positive_regulation of Gene_expression of SLC9A6 3 0.29 4.99 0 24.88
95 INT161220 Binding of Ccl2 17 0.46 17.63 4.94 24.40
96 INT59175 Localization of TNMD 4 0.70 4.14 0.71 21.60
97 INT269748 Positive_regulation of AMD1 4 0.43 3.56 0.28 20.88
98 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 20.60
99 INT118792 Regulation of Positive_regulation of AKT1 8 0.61 3.73 1.15 20.60
100 INT105336 Regulation of AKT1 52 0.56 32.53 4.89 20.20
101 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 20.00
102 INT164965 Gene_expression of Cle 4 0.58 3.73 0.1 17.12
103 INT311457 Positive_regulation of Cle 1 0.22 1.22 0 16.08
104 INT269220 Positive_regulation of Gene_expression of ITK 4 0.14 3.07 0.41 14.44
105 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 13.84
106 INT31989 Binding of SOD1 43 0.47 19.38 2.55 10.20
107 INT238458 Binding of GFM1 2 0.47 1.44 0 6.64
108 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
109 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 5.00
110 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 5.00
111 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
112 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
113 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 5.00
114 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
115 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 5.00
116 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
117 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
118 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
119 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
120 INT12339 Localization of IL8 437 0.81 251.87 117.39 5.00
121 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
122 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
123 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
124 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
125 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
126 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
127 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05 5.00
128 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 5.00
129 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
130 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 5.00
131 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 5.00
132 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
133 INT83953 Gene_expression of Cxcl2 140 0.75 113.07 43.65 5.00
134 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
135 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
136 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 5.00
137 INT48959 Positive_regulation of Positive_regulation of Prkcg 52 0.70 16.47 36.49 5.00
138 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 5.00
139 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69 5.00
140 INT65698 Localization of CCL2 118 0.81 77.54 32.69 5.00
141 INT9655 Regulation of Il6 98 0.62 70.92 31.95 5.00
142 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 5.00
143 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7 5.00
144 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 5.00
145 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47 5.00
146 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 5.00
147 INT10835 Regulation of IL8 79 0.49 53.04 24.14 5.00
148 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 5.00
149 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21 5.00
150 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
151 INT78901 Localization of CCL5 67 0.78 40.79 20.59 5.00
152 INT1764 Negative_regulation of Gene_expression of PTGER2 81 0.34 34.74 19.45 5.00
153 INT2006 Gene_expression of fc 104 0.34 64.91 19.08 5.00
154 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 5.00
155 INT66857 Regulation of CCL2 39 0.53 28.55 18.35 5.00
156 INT1767 Positive_regulation of PROC 83 0.67 54.14 17 5.00
157 INT110767 Localization of Mcpt1 43 0.68 24.3 16.74 5.00
158 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 5.00
159 INT59870 Gene_expression of F3 51 0.65 51.83 14.01 5.00
160 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 5.00
161 INT12135 Gene_expression of PLEK 62 0.75 34.13 12.47 5.00
162 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 5.00
163 INT59080 Negative_regulation of Gene_expression of PTGS2 55 0.58 22.92 12.39 5.00
164 INT8629 Positive_regulation of COL7A1 72 0.69 40.66 12.09 5.00
165 INT1763 Regulation of Gene_expression of PTGER2 43 0.36 23.98 10.95 5.00
166 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4 5.00
167 INT2036 Localization of EGF 42 0.77 21.5 9.74 5.00
168 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 5.00
169 INT80036 Positive_regulation of FAS 42 0.67 42.22 9.4 5.00
170 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37 5.00
171 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82 5.00
172 INT59165 Binding of fc 67 0.36 37.51 8.68 5.00
173 INT112967 Regulation of Mcpt1 15 0.54 13.03 8.58 5.00
174 INT22383 Binding of IL2 59 0.48 39.06 8.56 5.00
175 INT119904 Regulation of CYP19A1 25 0.62 9.36 8.34 5.00
176 INT182229 Positive_regulation of CCL16 15 0.66 12.19 8.21 5.00
177 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 5.00
178 INT173537 Binding of CCL16 18 0.40 13.02 7.36 5.00
179 INT110599 Gene_expression of Bglap 49 0.74 41.23 6.97 5.00
180 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06 5.00
181 INT75832 Positive_regulation of Positive_regulation of IL8 30 0.70 20.77 6.05 5.00
182 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78 5.00
183 INT125534 Regulation of Tg(CAG-EGFP)D4Nagy 31 0.39 13.88 5.58 5.00
184 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56 5.00
185 INT136664 Positive_regulation of Gene_expression of Twist1 49 0.69 25.91 5.41 5.00
186 INT23010 Positive_regulation of CYP19A1 28 0.58 24.18 5.37 5.00
187 INT187295 Gene_expression of Serpinb1a 6 0.58 13.73 5.05 5.00
188 INT26167 Positive_regulation of Hrasls 18 0.23 8.67 4.87 5.00
189 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79 5.00
190 INT82354 Positive_regulation of PECAM1 25 0.34 22.93 4.69 5.00
191 INT73309 Regulation of Negative_regulation of PTGS2 14 0.44 9.55 4.5 5.00
192 INT83955 Regulation of Cxcl2 14 0.58 9.77 4.45 5.00
193 INT98357 Binding of Gnas 11 0.41 1.87 4.35 5.00
194 INT19449 Binding of FANCB 22 0.47 7.4 4.27 5.00
195 INT171040 Transcription of CCL16 11 0.68 7.09 3.86 5.00
196 INT97638 Localization of CCL16 11 0.66 4.89 3.74 5.00
197 INT86369 Positive_regulation of Gene_expression of PCNA 40 0.67 26.66 3.57 5.00
198 INT8096 Positive_regulation of Gene_expression of EGF 21 0.69 13.43 3.47 5.00
199 INT124606 Positive_regulation of Gene_expression of Mpo 14 0.49 12.66 3.24 5.00
200 INT107514 Positive_regulation of Akr1b1 6 0.70 7.64 3.21 5.00
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