D:Endotoxemia

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pChart

Disease Term
Synonyms Endotoxemias
Documents 302
Hot Single Events 200
Hot Interactions 48

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Endotoxemia. They are ordered first by their relevance to Endotoxemia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT126227 Hsp90aa1 Positive_regulation of Nos1 1 0.03 0.73 0.25 100.00
2 INT285605 Binding of ROS1 and Tlr4 1 0.01 1.25 0.16 99.96
3 INT316481 Positive_regulation of Stat3 Positive_regulation of Localization of Hand1 1 0.19 1.48 0.03 98.76
4 INT337297 PTAFR Positive_regulation of EDNRA 1 0.04 1.2 0.06 98.64
5 INT337303 Positive_regulation of PTAFR Positive_regulation of EDNRA 1 0.04 1.21 0.06 98.64
6 INT132448 MIR3607 Negative_regulation of IL6 1 0.01 2.45 0.48 98.52
7 INT323611 Il1 Regulation of Hmgb1 1 0.17 2.36 0.55 98.16
8 INT242883 INS Negative_regulation of Gene_expression of TLR2 1 0.17 2.35 0.6 98.08
9 INT242875 INS Negative_regulation of Gene_expression of TLR4 1 0.11 1.41 0.24 98.08
10 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68 96.88
11 INT132445 TF Positive_regulation of IL8 1 0.11 2.23 0.46 96.76
12 INT200536 Ca2 Positive_regulation of NOS1 1 0.03 0.74 0.07 95.92
13 INT337302 PLA2G6 Regulation of Gene_expression of PTAFR 1 0.09 1.18 0.07 95.64
14 INT159351 Negative_regulation of Binding of Nos1 and Nos2 1 0.27 0.34 0.22 95.36
15 INT159348 Binding of Nos1 and Nos2 1 0.23 0.29 0.22 94.84
16 INT132447 TF Positive_regulation of IL6 1 0.09 1.1 0.23 94.12
17 INT91686 Mb Positive_regulation of Edn1 1 0.03 0.29 0.22 92.00
18 INT283259 MIR146B Positive_regulation of Gene_expression of IRF6 1 0.01 0.95 0 91.76
19 INT283254 MIR150 Positive_regulation of Gene_expression of IRF6 1 0.04 0.95 0 91.76
20 INT283258 MIR342 Positive_regulation of Gene_expression of IRF6 1 0.02 0.96 0 91.76
21 INT281300 Tlr4 Positive_regulation of Gene_expression of tf 1 0.12 2.5 0 91.60
22 INT329722 Binding of Il10rb and Il10 1 0.00 0.79 0.51 91.12
23 INT329721 Positive_regulation of Binding of Il10rb and Il10 1 0.00 0.79 0.51 91.12
24 INT297314 Binding of Bsg and Sele 1 0.11 1.37 0.37 89.28
25 INT242878 INS Negative_regulation of Gene_expression of SPI1 1 0.04 1.81 0.27 88.80
26 INT162343 Positive_regulation of KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23 88.12
27 INT162344 KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23 88.12
28 INT215097 Tlr4 Positive_regulation of Localization of Gopc 1 0.11 0.16 0.03 87.44
29 INT190527 TNF Positive_regulation of Gene_expression of Ros1 1 0.01 1.02 0.68 87.28
30 INT190526 Acot1 Positive_regulation of Il1 1 0.01 0.87 0.63 87.04
31 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46 86.40
32 INT222283 Negative_regulation of Casp1 Negative_regulation of Il1a 1 0.00 0.78 0.46 86.40
33 INT303947 Binding of LEPR and TXK 1 0.00 0.63 0 86.16
34 INT343825 IRF6 Regulation of Gene_expression of FUT1 1 0.00 1.74 0.5 86.08
35 INT283256 MIR150 Regulation of Gene_expression of MYB 1 0.12 0.83 0 85.52
36 INT303987 Binding of LEPR and Fyn 1 0.02 0.62 0 85.48
37 INT190525 Acot1 Positive_regulation of Localization of S100a8 1 0.00 0.86 0.63 85.28
38 INT323593 IRF6 Positive_regulation of PROCR 1 0.00 0.46 0.19 84.88
39 INT323592 IRF6 Positive_regulation of Positive_regulation of PROCR 1 0.00 0.46 0.19 84.88
40 INT310311 Tlr4 Positive_regulation of Gpt 1 0.05 1.15 0.12 84.68
41 INT285604 ROS1 Positive_regulation of Gene_expression of Tlr4 1 0.01 1.14 0.2 82.24
42 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 81.84
43 INT343834 Binding of CD14 and IRF6 1 0.02 2.08 0.9 81.84
44 INT343859 Binding of IRF6 and TBCE 1 0.01 1.1 0.51 81.84
45 INT343860 Binding of CD14 and TBCE 1 0.03 1.1 0.51 81.84
46 INT159349 Zfp956 Negative_regulation of Nos1 1 0.03 0.61 0.43 80.72
47 INT339394 Binding of Nfkb1 and Gtf3a 1 0.00 0.52 0.14 80.32
48 INT339392 Binding of Nfib and Gtf3a 1 0.00 0.53 0.14 80.32
49 INT159350 Zfp956 Negative_regulation of Nos2 1 0.03 0.3 0.21 78.88
50 INT303963 Lep Positive_regulation of Gene_expression of Il7 1 0.02 0.41 0 78.32
51 INT262809 Il10 Positive_regulation of Regulation of Slc11a1 1 0.17 1.12 0.27 75.96
52 INT268768 Mip Regulation of Positive_regulation of Ccr1 1 0.44 0.83 0.23 75.00
53 INT281321 STX1A Positive_regulation of Gene_expression of tf 1 0.07 0.96 0 74.96
54 INT306019 Binding of Tlr4 and LY96 1 0.06 0.91 0.49 73.84
55 INT276602 Paf Positive_regulation of Gene_expression of Mthfd1 1 0.13 0.37 0.31 72.88
56 INT276604 Tlr4 Positive_regulation of Gene_expression of Paf 1 0.22 0.37 0.31 72.32
57 INT276605 Tlr4 Positive_regulation of Gene_expression of Mthfd1 1 0.06 0.37 0.31 72.32
58 INT281310 Stx2 Positive_regulation of Gene_expression of tf 1 0.20 0.89 0 71.80
59 INT339393 Tlr4 Positive_regulation of Nfkb1 1 0.24 2.06 0.61 71.76
60 INT281319 Binding of F7 and tf 1 0.24 1 0.16 71.36
61 INT328299 Binding of GHRH and GHS 1 0.07 2.21 0.31 70.92
62 INT281305 Binding of St8sia2 and Tlr4 1 0.02 0.98 0 69.84
63 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61 69.00
64 INT297333 Apoe Negative_regulation of Positive_regulation of Tlr4 1 0.10 1.02 0.14 65.20
65 INT276598 Il10 Positive_regulation of Gene_expression of Paf 1 0.29 0.49 0.6 62.84
66 INT276597 Paf Positive_regulation of Il10 1 0.27 0.48 0.6 62.84
67 INT276603 Il10 Positive_regulation of Gene_expression of Tlr4 1 0.12 0.49 0.6 62.84
68 INT262810 Slc11a1 Positive_regulation of Gene_expression of Il10 1 0.20 0.97 0.27 62.48
69 INT297343 Binding of Apoe and Tlr4 1 0.09 0.94 0.14 59.84
70 INT268925 Igfbp2 Negative_regulation of Phosphorylation of Mapk14 1 0.01 0.35 0.08 59.44
71 INT320694 C5 Regulation of Gene_expression of Il2 1 0.03 2.15 0.34 58.88
72 INT320692 C5 Regulation of Gene_expression of Il12a 1 0.03 2.15 0.34 58.88
73 INT320693 C5 Regulation of Gene_expression of Il6 1 0.04 2.15 0.34 58.88
74 INT320696 C5 Regulation of Gene_expression of TNF 1 0.34 2.15 0.34 58.88
75 INT320691 C5 Regulation of Gene_expression of Il1 1 0.06 2.15 0.34 58.88
76 INT291041 IL6 Regulation of IL36RN 1 0.00 1.09 0.17 58.64
77 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73 57.28
78 INT310301 Casr Regulation of Tlr4 1 0.04 0.48 0.08 55.76
79 INT297339 Tlr4 Negative_regulation of Gene_expression of Apoe 1 0.10 0.73 0.13 55.12
80 INT297316 Negative_regulation of Rock2 Positive_regulation of Cdh1 1 0.01 1.92 0.43 52.32
81 INT343827 MIRLET7I Regulation of Gene_expression of TLR4 1 0.00 0.13 0.19 51.92
82 INT281317 Stx2 Regulation of Gene_expression of tf 1 0.11 1.45 0.03 51.28
83 INT281313 Tlr4 Regulation of Gene_expression of tf 1 0.05 1.45 0.03 51.28
84 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68 50.88
85 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61 50.24
86 INT268766 Tlr4 Positive_regulation of Gene_expression of Ccr1 1 0.04 0.4 0.26 50.00
87 INT268765 Tlr4 Positive_regulation of Positive_regulation of Ccr1 1 0.04 0.27 0.13 50.00
88 INT281302 Binding of Itgam and Fgg 1 0.00 0.62 0.15 48.24
89 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91 47.68
90 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91 47.68
91 INT348786 Tlr4 Positive_regulation of Mapk8 1 0.33 1.09 0.11 45.52
92 INT262257 Positive_regulation of NOS2 Positive_regulation of AMIGO2 1 0.02 0.99 0.16 44.80
93 INT281315 Binding of Gp1bb and Itgam 1 0.00 0.62 0.15 44.40
94 INT324828 ELANE Positive_regulation of Localization of Ecm1 1 0.00 0.61 0.09 43.44
95 INT316491 Socs3 Positive_regulation of Il11ra1 1 0.45 0.92 0.22 42.12
96 INT337293 PTAFR Positive_regulation of Positive_regulation of TLR4 1 0.62 1.43 0.28 41.52
97 INT215095 Negative_regulation of Il6 Positive_regulation of Hmgb1 1 0.13 1.03 0.09 40.52
98 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84 40.12
99 INT215094 Il6 Positive_regulation of Hmgb1 1 0.18 1.84 0.17 39.72
100 INT347416 Tlr4 Negative_regulation of SOD1 1 0.00 0.36 0.04 36.64
101 INT347414 Tlr4 Negative_regulation of Gpx1 1 0.01 0.36 0.04 36.00
102 INT329797 Positive_regulation of TLR2 Positive_regulation of Gene_expression of IL6 1 0.02 1.67 0.11 32.76
103 INT329802 Positive_regulation of TLR2 Regulation of Gene_expression of IL6 1 0.01 1.67 0.11 32.76
104 INT132457 Binding of TF and Gtf3a 1 0.01 0.64 0.17 28.00
105 INT132446 Binding of TF and COBRA1 1 0.01 0.63 0.17 27.36
106 INT132456 Binding of COBRA1 and Gtf3a 1 0.00 0.63 0.17 27.36
107 INT303966 Lep Regulation of Il1 2 0.09 0.41 0.1 23.68
108 INT324829 ROS1 Positive_regulation of Gene_expression of Ecm1 1 0.00 0.66 0.09 21.12
109 INT297330 Apoe Positive_regulation of Gene_expression of Nos2 1 0.26 0.34 0.07 20.16
110 INT303967 Lep Positive_regulation of Gene_expression of Icam1 1 0.24 0.58 0.16 14.40
111 INT303999 Lep Positive_regulation of Gene_expression of ITGA2 1 0.06 0.29 0.08 14.40
112 INT303970 Lep Positive_regulation of Gene_expression of Itga2 1 0.09 0.29 0.08 14.40
113 INT303989 Lep Positive_regulation of IL12A 1 0.05 0.39 0.11 13.44
114 INT337295 PTAFR Positive_regulation of Localization of STAT3 1 0.43 0.85 0.22 10.84
115 INT281318 Binding of Selp and Selplg Positive_regulation of Gene_expression of Selplg 1 0.00 0.76 0.17 9.68
116 INT260739 Mapk14 Regulation of Positive_regulation of Sp1 1 0.01 1.06 0.25 8.56
117 INT281322 Binding of PLEK and Tlr4 1 0.15 1.41 0 8.48
118 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08 8.24
119 INT337304 PTAFR Positive_regulation of Gene_expression of TLR4 1 0.62 1.99 0.36 7.24
120 INT308352 Binding of Ctnnd2 and Tcf7l2 1 0.15 0.74 0 7.00
121 INT236720 Binding of Ctnnd2 and Tcf4 3 0.24 2.8 0 7.00
122 INT281307 Binding of Selp and Selplg 1 0.01 0.76 0.17 5.28
123 INT281320 Binding of PLEK and St8sia2 1 0.06 0.38 0 5.24
124 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47 5.00
125 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
126 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27 5.00
127 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58 5.00
128 INT190524 Ros1 Positive_regulation of Nfkb1 3 0.02 4.24 2.06 5.00
129 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95 5.00
130 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95 5.00
131 INT100771 Binding of Itga1 and Vcam1 3 0.11 3.91 1.79 5.00
132 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47 5.00
133 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47 5.00
134 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32 5.00
135 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21 5.00
136 INT328742 Il1 Positive_regulation of Mapk14 1 0.01 1.4 1.2 5.00
137 INT43509 Avp Positive_regulation of Localization of POMC 2 0.13 1.26 1.16 5.00
138 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15 5.00
139 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12 5.00
140 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06 5.00
141 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 5.00
142 INT175805 Crh Positive_regulation of Gene_expression of POMC 1 0.12 1.07 0.99 5.00
143 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9 5.00
144 INT297332 Apoe Negative_regulation of Gene_expression of Mpz 1 0.02 1.09 0.87 5.00
145 INT343847 IRF6 Positive_regulation of TBCE 1 0.01 1.11 0.87 5.00
146 INT297336 1700061J05Rik Negative_regulation of Gene_expression of Mpz 1 0.00 1.08 0.86 5.00
147 INT244323 Csf2 Positive_regulation of Gene_expression of Tlr4 1 0.23 1.93 0.85 5.00
148 INT343829 TLR1 Positive_regulation of TBCE 1 0.03 0.96 0.85 5.00
149 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84 5.00
150 INT196632 IL1B Positive_regulation of F2RL1 2 0.05 1.52 0.84 5.00
151 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82 5.00
152 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77 5.00
153 INT183698 Binding of Cxcr2 and Cxcl1 3 0.33 3.26 0.76 5.00
154 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73 5.00
155 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73 5.00
156 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69 5.00
157 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69 5.00
158 INT297307 Negative_regulation of Binding of Ccr1 and Ccl3 1 0.27 0.73 0.67 5.00
159 INT297313 Negative_regulation of Binding of Ccr1 and Ccl5 1 0.28 0.74 0.67 5.00
160 INT306020 Binding of LBP and Tlr4 1 0.13 0.34 0.66 5.00
161 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66 5.00
162 INT244320 Tlr4 Positive_regulation of Aliq1 3 0.04 4.51 0.64 5.00
163 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63 5.00
164 INT297344 Apoe Regulation of Binding of Alms1 1 0.08 1.1 0.61 5.00
165 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6 5.00
166 INT208372 Il13 Positive_regulation of Ahr 1 0.21 1.22 0.59 5.00
167 INT272146 PTAFR Positive_regulation of Localization of IL8 3 0.38 0.28 0.59 5.00
168 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58 5.00
169 INT297331 Apoe Negative_regulation of Gene_expression of Il6 1 0.14 0.61 0.57 5.00
170 INT146871 Tlr4 Positive_regulation of Gene_expression of ROS1 2 0.00 1.16 0.56 5.00
171 INT195666 Binding of PROC and THBD 2 0.40 2.42 0.56 5.00
172 INT328744 TNF Regulation of Positive_regulation of Mapk14 1 0.02 0.81 0.55 5.00
173 INT297311 Casp1 Positive_regulation of Il18 1 0.09 1.02 0.55 5.00
174 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54 5.00
175 INT215101 Hmgb1 Positive_regulation of Localization of Il6 4 0.16 1.18 0.54 5.00
176 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52 5.00
177 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51 5.00
178 INT324816 Hspd1 Positive_regulation of Gene_expression of Ik 1 0.00 1.59 0.5 5.00
179 INT253770 Hmgb1 Positive_regulation of Localization of Apex1 1 0.08 0.71 0.49 5.00
180 INT319718 Binding of Crebbp and Creb1 1 0.10 1.68 0.48 5.00
181 INT244319 Csf2 Positive_regulation of Positive_regulation of Tlr4 1 0.23 1.03 0.48 5.00
182 INT132792 IL4 Positive_regulation of IL6 4 0.28 1.81 0.47 5.00
183 INT196634 IFNG Negative_regulation of DNAH8 1 0.03 1.49 0.47 5.00
184 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46 5.00
185 INT175788 Il2 Positive_regulation of Localization of Avp 1 0.03 0.41 0.46 5.00
186 INT328385 Binding of GHS and Ghrl 1 0.15 1.89 0.45 5.00
187 INT296795 Binding of Tlr9 and Tlr3 2 0.22 1.29 0.45 5.00
188 INT329794 TLR2 Positive_regulation of Positive_regulation of IL12A 1 0.01 1.05 0.44 5.00
189 INT175802 Il1 Positive_regulation of Gene_expression of Fos 1 0.00 0.66 0.44 5.00
190 INT343846 MAPK1 Positive_regulation of FOS 1 0.04 1.29 0.44 5.00
191 INT348784 Ins1 Positive_regulation of Irs1 1 0.09 3.47 0.44 5.00
192 INT320695 TNF Positive_regulation of Localization of Il1 1 0.05 1.38 0.44 5.00
193 INT230461 Binding of TLR1 and TLR2 3 0.33 2.06 0.43 5.00
194 INT343853 IRF6 Positive_regulation of PECAM1 1 0.00 0.53 0.43 5.00
195 INT328377 Binding of GAST and Ghrl 1 0.03 0.62 0.43 5.00
196 INT348785 Ins1 Positive_regulation of Phosphorylation of Akt1 1 0.17 3.5 0.42 5.00
197 INT343916 Hspa1a Positive_regulation of Gene_expression of TNF 1 0.16 1.17 0.41 5.00
198 INT329803 TLR2 Positive_regulation of Positive_regulation of IL6 1 0.01 0.94 0.41 5.00
199 INT329800 TLR2 Positive_regulation of Positive_regulation of IL8 1 0.01 0.99 0.41 5.00
200 INT316493 Il6 Positive_regulation of Il11ra1 1 0.64 1.69 0.4 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Endotoxemia. They are ordered first by their pain relevance and then by number of times they were reported in Endotoxemia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 100.00
2 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 100.00
3 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 100.00
4 INT49253 Regulation of Gene_expression of EDN1 11 0.61 3.92 2.07 100.00
5 INT69035 Positive_regulation of Casp1 43 0.69 25.18 10.67 99.98
6 INT22045 Gene_expression of IRF6 158 0.75 58.07 27.81 99.96
7 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89 99.96
8 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 99.96
9 INT88861 Positive_regulation of Gene_expression of Hsp90aa1 4 0.64 7.43 0.9 99.96
10 INT77656 Gene_expression of Hsp90aa1 12 0.78 24.27 1.81 99.96
11 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 99.96
12 INT8233 Positive_regulation of Gene_expression of Paf 5 0.49 3.76 2.24 99.96
13 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.90
14 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 99.90
15 INT195693 Regulation of CA13 1 0.14 1.15 0 99.90
16 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 99.90
17 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36 99.90
18 INT5506 Positive_regulation of Gene_expression of Pomc 132 0.70 26.78 54.3 99.90
19 INT15517 Regulation of Paf 5 0.45 6.74 3.06 99.88
20 INT200534 Phosphorylation of Tnni1 5 0.16 2.05 0.21 99.88
21 INT200533 Negative_regulation of Phosphorylation of Tnni1 1 0.08 1.1 0.13 99.88
22 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 99.86
23 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96 99.86
24 INT50672 Positive_regulation of CPOX 205 0.44 125.93 60.06 99.86
25 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 99.82
26 INT2520 Negative_regulation of Ca2 271 0.57 72.13 83.71 99.82
27 INT180595 Regulation of IBSP 2 0.09 1.29 0.38 99.82
28 INT37835 Negative_regulation of CPP 61 0.51 31.34 18.57 99.82
29 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62 99.82
30 INT116737 Localization of Mif 63 0.81 52.97 28.11 99.76
31 INT10166 Localization of Tnf 237 0.81 153.95 88.64 99.74
32 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 99.72
33 INT6852 Localization of TNF 883 0.81 705.95 270.84 99.68
34 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 99.68
35 INT63170 Positive_regulation of Selp 27 0.68 24.1 6.3 99.68
36 INT166881 Positive_regulation of Ccr1 31 0.69 18.14 7.9 99.68
37 INT1032 Regulation of Ca2 202 0.52 54.91 53.03 99.68
38 INT62525 Positive_regulation of SELE 38 0.70 46 5.25 99.68
39 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 99.68
40 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99 99.68
41 INT82168 Positive_regulation of S100b 20 0.68 9.72 3.08 99.68
42 INT56446 Positive_regulation of Positive_regulation of Icam1 7 0.40 8.84 1.64 99.66
43 INT36262 Positive_regulation of Tbce 35 0.49 28.79 14.33 99.66
44 INT228038 Positive_regulation of Gene_expression of Tbce 3 0.07 2.02 1.01 99.66
45 INT63169 Positive_regulation of Gene_expression of Selp 35 0.69 21.95 7.16 99.56
46 INT71115 Positive_regulation of Gene_expression of Serpine1 20 0.70 15.32 1.97 99.56
47 INT200599 Positive_regulation of Positive_regulation of Plg 3 0.07 2.11 0.1 99.56
48 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 99.56
49 INT195692 Negative_regulation of CA13 1 0.18 2.18 0.05 99.50
50 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 99.38
51 INT210590 Positive_regulation of Gene_expression of Mip 10 0.67 8.09 1.68 99.36
52 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 99.36
53 INT23226 Positive_regulation of tf 23 0.43 15.55 14.37 99.32
54 INT56447 Positive_regulation of Icam1 64 0.64 64.14 16.16 99.32
55 INT81443 Positive_regulation of Vcam1 29 0.63 28.4 6.35 99.32
56 INT74109 Positive_regulation of Sele 26 0.48 22.32 5.84 99.32
57 INT23465 Gene_expression of S100b 31 0.76 15.09 6.2 99.32
58 INT19775 Localization of Il1 183 0.78 145.5 50.91 99.28
59 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23 99.28
60 INT53572 Negative_regulation of Localization of Il1 18 0.40 12.78 6.7 99.28
61 INT63121 Binding of APC 29 0.41 23.02 3.8 99.28
62 INT49141 Gene_expression of Selp 157 0.78 85.22 24.78 99.24
63 INT20102 Gene_expression of Serpine1 102 0.78 65.99 12.61 99.24
64 INT141611 Positive_regulation of Gene_expression of Ccr1 25 0.69 20.32 6.42 99.20
65 INT339 Regulation of Trh 156 0.62 39.27 83.55 99.20
66 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 99.18
67 INT257816 Negative_regulation of PAFAH1B1 1 0.58 3.66 0.49 99.18
68 INT8232 Gene_expression of Paf 21 0.67 22.18 12.8 99.16
69 INT3818 Regulation of Apc 13 0.39 12.52 1.68 99.08
70 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 99.04
71 INT64499 Positive_regulation of IRF6 123 0.49 52.73 27.51 99.02
72 INT141612 Gene_expression of Ccr1 92 0.77 72.09 24.14 99.00
73 INT69867 Gene_expression of Mip 36 0.75 24.54 10.38 99.00
74 INT93658 Transcription of Nos1 16 0.72 6.85 6.16 99.00
75 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59 98.96
76 INT145650 Localization of PLA2G6 15 0.76 8.87 2.06 98.96
77 INT81537 Regulation of Gene_expression of Nfkb1 10 0.57 7.09 7.48 98.96
78 INT65538 Regulation of Positive_regulation of Nfkb1 17 0.51 8.31 6.5 98.96
79 INT16879 Binding of Crh 72 0.48 21.65 28.43 98.94
80 INT6365 Localization of Edn1 56 0.81 18.84 13.83 98.92
81 INT200581 Negative_regulation of Negative_regulation of AVP 1 0.41 0.46 0 98.92
82 INT39057 Regulation of Pgf 2 0.28 0.52 0.29 98.88
83 INT9660 Regulation of TNF 363 0.62 312.94 139.99 98.88
84 INT9210 Regulation of IL6 166 0.62 125.61 49.95 98.88
85 INT220326 Negative_regulation of FECD7 4 0.05 2.79 0 98.84
86 INT42707 Gene_expression of Tbce 24 0.65 12.92 7.93 98.80
87 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 98.76
88 INT129584 Positive_regulation of Stat3 97 0.68 87.07 14.86 98.76
89 INT16478 Positive_regulation of Plg 29 0.45 18.07 4.07 98.76
90 INT17548 Negative_regulation of Serpine1 30 0.57 24.69 3.93 98.74
91 INT65536 Negative_regulation of Positive_regulation of Nfkb1 77 0.59 38.86 33.33 98.72
92 INT65055 Negative_regulation of Nfkb1 83 0.58 44.85 34.94 98.72
93 INT21545 Regulation of DNAH8 22 0.59 8.67 6.48 98.72
94 INT20129 Regulation of Il1 53 0.53 44.14 19.89 98.72
95 INT60933 Positive_regulation of Apcs 16 0.67 11.69 3.68 98.68
96 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91 98.66
97 INT13303 Positive_regulation of PTAFR 40 0.69 16.27 11.56 98.64
98 INT181022 Binding of Ccr1 15 0.37 10.69 5.37 98.64
99 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 98.64
100 INT70905 Positive_regulation of EDNRA 49 0.67 24.33 11.79 98.64
101 INT55469 Positive_regulation of Positive_regulation of PTAFR 9 0.47 3 2.17 98.64
102 INT335999 Positive_regulation of Gene_expression of H2-S 3 0.49 3.39 0.67 98.64
103 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 98.62
104 INT17886 Negative_regulation of Il1 95 0.57 70.91 31.25 98.60
105 INT200583 Negative_regulation of HLA-DOB 1 0.01 2.61 0.23 98.60
106 INT200580 Negative_regulation of Negative_regulation of HLA-DOB 1 0.01 0.59 0.05 98.60
107 INT4853 Regulation of Hrh2 42 0.45 22.34 16.65 98.60
108 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 98.56
109 INT53574 Regulation of Tnf 45 0.62 40.68 19.71 98.56
110 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 98.52
111 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 98.52
112 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85 98.48
113 INT104388 Positive_regulation of Gene_expression of Cxcl2 31 0.66 25.68 7.49 98.48
114 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 98.46
115 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33 98.44
116 INT162361 Positive_regulation of Gene_expression of KCNMA1 6 0.46 2.44 1.25 98.44
117 INT11479 Positive_regulation of KCNMA1 30 0.68 10.07 10.82 98.44
118 INT114874 Gene_expression of Stat3 78 0.76 53.99 9.49 98.44
119 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15 98.40
120 INT10982 Negative_regulation of Agtr1a 42 0.58 22.42 10.29 98.36
121 INT5536 Regulation of NA 74 0.59 16.61 15.36 98.36
122 INT172412 Negative_regulation of SV2A 6 0.47 0.88 0.74 98.36
123 INT78480 Localization of Nfkb1 39 0.80 23.14 13.64 98.32
124 INT92398 Negative_regulation of Localization of Nfkb1 17 0.42 11.24 5.4 98.32
125 INT65390 Positive_regulation of Plat 30 0.70 23.31 9.31 98.28
126 INT138660 Positive_regulation of Regulation of Grin1 2 0.24 1.59 1.71 98.24
127 INT7340 Regulation of Grin1 87 0.62 30.37 57.93 98.24
128 INT190520 Negative_regulation of Hmgb1 24 0.53 20.08 5.6 98.22
129 INT1045 Localization of LH 1211 0.81 87.04 456.25 98.22
130 INT77853 Positive_regulation of Gene_expression of tf 20 0.31 22.75 5.94 98.20
131 INT1376 Binding of Trh 121 0.48 20 69.86 98.20
132 INT64558 Negative_regulation of Nos1 88 0.58 26.76 36.78 98.12
133 INT81530 Gene_expression of Nfkb1 93 0.78 48.58 32.58 98.08
134 INT102268 Gene_expression of H2-S 20 0.75 10.77 2.03 98.08
135 INT78057 Localization of Tlr4 140 0.77 67.75 21.72 98.04
136 INT157622 Positive_regulation of Localization of Tlr4 34 0.48 22.63 5.09 98.04
137 INT52591 Gene_expression of KCNMA1 78 0.76 13.95 15.55 98.04
138 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05 98.04
139 INT107291 Positive_regulation of Ghrl 58 0.67 44.6 9.68 98.04
140 INT23035 Regulation of Il1a 6 0.60 5.69 4.25 98.00
141 INT116054 Phosphorylation of Prkg1 3 0.80 0.91 0.44 98.00
142 INT134073 Negative_regulation of Phosphorylation of Prkg1 2 0.41 0.92 0.36 98.00
143 INT116050 Positive_regulation of Phosphorylation of Prkg1 2 0.28 0.76 0.16 98.00
144 INT23224 Gene_expression of tf 99 0.56 60.22 22.03 97.92
145 INT111195 Negative_regulation of Gene_expression of Agtr1a 7 0.58 3.2 3.16 97.92
146 INT179219 Regulation of AMIGO2 1 0.09 3.88 1.3 97.92
147 INT69929 Gene_expression of S100a9 11 0.77 16.12 5.79 97.92
148 INT69928 Regulation of Gene_expression of S100a9 2 0.26 0.86 0.21 97.92
149 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26 97.88
150 INT215071 Positive_regulation of Localization of Hmgb1 34 0.63 22.03 4.15 97.88
151 INT11937 Localization of Il6 228 0.81 139.83 64.39 97.84
152 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89 97.84
153 INT13286 Gene_expression of Ca2 317 0.67 71.58 65.01 97.80
154 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 97.76
155 INT100360 Negative_regulation of TF 19 0.42 10.43 2.68 97.76
156 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 97.72
157 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 97.72
158 INT83953 Gene_expression of Cxcl2 140 0.75 113.07 43.65 97.72
159 INT215086 Positive_regulation of Inadl 2 0.01 2.13 0.39 97.72
160 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 97.64
161 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17 97.64
162 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09 97.62
163 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69 97.62
164 INT81531 Positive_regulation of Gene_expression of Nfkb1 27 0.69 13.9 11.04 97.62
165 INT61953 Transcription of Nos2 101 0.72 46.64 25.49 97.60
166 INT23415 Regulation of Hils1 2 0.27 0.29 1.18 97.56
167 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 97.48
168 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37 97.48
169 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 97.48
170 INT195698 Positive_regulation of CA13 1 0.22 1.75 0.13 97.44
171 INT195688 Positive_regulation of Positive_regulation of CA13 1 0.22 0.27 0 97.44
172 INT120966 Positive_regulation of Pik3cb 34 0.68 15.15 16.59 97.40
173 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49 97.36
174 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19 97.36
175 INT11141 Negative_regulation of Gene_expression of Avp 23 0.59 3.85 12.19 97.36
176 INT178711 Protein_catabolism of Tlr4 15 0.84 6.75 3.19 97.36
177 INT50272 Positive_regulation of Cotl1 24 0.40 6.57 2.77 97.32
178 INT19759 Gene_expression of LBP 77 0.77 56.44 33.23 97.28
179 INT76096 Positive_regulation of Gene_expression of IRF6 37 0.49 14.24 6.39 97.08
180 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 97.08
181 INT477 Localization of Avp 813 0.81 131.58 300.4 97.08
182 INT119195 Binding of Cotl1 11 0.14 6.77 2.21 97.08
183 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 97.00
184 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 96.92
185 INT48956 Negative_regulation of Positive_regulation of Nos2 34 0.46 13.15 11.15 96.92
186 INT61951 Regulation of Negative_regulation of Nos2 5 0.58 3.08 1.39 96.92
187 INT20378 Localization of Hand1 53 0.71 41.96 13.31 96.92
188 INT215074 Negative_regulation of Localization of Hmgb1 28 0.57 15.09 4 96.88
189 INT35406 Localization of Tnf 94 0.81 64.63 31.65 96.84
190 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54 96.84
191 INT105723 Negative_regulation of Mat1a 2 0.41 0.96 0.58 96.84
192 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 96.80
193 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 96.80
194 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 96.64
195 INT76924 Positive_regulation of Slc17a5 71 0.70 41.21 19.31 96.64
196 INT5160 Localization of PTAFR 61 0.80 42.6 19.16 96.64
197 INT20851 Regulation of Adra1d 2 0.42 0.4 0.73 96.62
198 INT99001 Negative_regulation of Selp 23 0.59 16.68 4.74 96.60
199 INT6481 Binding of TNF 624 0.48 510.2 214.82 96.48
200 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 96.48
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