D:Epidermal Cyst

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Disease Term
Synonyms CYST EPIDERMAL, Cyst Epidermoid, CYST PILAR, Cyst Sebaceous, Cysts Epidermal, Cysts Epidermoid, Cysts Pilar, CYSTS SEBACEOUS, EPIDERMAL CYSTS, Epidermoid Cyst, Epidermoid Cysts
Documents 211
Hot Single Events 14
Hot Interactions 6

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Epidermal Cyst. They are ordered first by their relevance to Epidermal Cyst and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT164433 Il12a Positive_regulation of Il6 1 0.01 1.71 0.29 100.00
2 INT164434 Il12a Positive_regulation of Tnf 1 0.00 1.7 0.29 100.00
3 INT164432 Ifng Positive_regulation of Tnf 1 0.01 1.71 0.29 100.00
4 INT164431 Ifng Positive_regulation of Il6 1 0.01 1.71 0.29 100.00
5 INT286113 Binding of Fap and Rpe65 1 0.04 1.97 0 85.28
6 INT286110 Binding of Rpe65 and Gopc 1 0.01 1.97 0 85.28
7 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19 5.00
8 INT279889 Il6 Regulation of Socs3 1 0.21 0.17 0.05 5.00
9 INT279885 Ctcf Regulation of H19 1 0.12 0 0 5.00
10 INT241588 Binding of FAS and Fas 1 0.05 2.34 0 5.00
11 INT286114 Binding of MSH6 and Mutyh 1 0.17 0 0 5.00
12 INT279891 Shbdp1 Negative_regulation of PCDHB@ 1 0.01 0.09 0 5.00
13 INT286111 Binding of Rpa3 and Mutyh 1 0.30 0 0 5.00
14 INT286112 Binding of Apc and Afap1 1 0.05 0.71 0 5.00
15 INT279886 Shbdp1 Negative_regulation of Pcdhb1 1 0.10 0.09 0 5.00
16 INT286115 Binding of APEX1 and Mutyh 1 0.10 0 0 5.00
17 INT279884 Nipbl Regulation of Transcription of Pcdhb1 1 0.25 0.05 0 5.00
18 INT279892 Shbdp1 Negative_regulation of Gene_expression of PCDHB@ 1 0.01 0.09 0 5.00
19 INT256632 Binding of PTCH1 and Jkamp 1 0.00 2.32 0 5.00
20 INT286109 Binding of Pcna and Mutyh 1 0.30 0 0 5.00
21 INT279888 Binding of Rec8 and Nipbl 1 0.01 0.81 0 5.00
22 INT279890 Nipbl Regulation of Gene_expression of PCDHB@ 1 0.07 0.1 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Epidermal Cyst. They are ordered first by their pain relevance and then by number of times they were reported in Epidermal Cyst. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT225667 Transcription of Apc 3 0.52 3.73 0.32 99.84
2 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 99.68
3 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05 99.68
4 INT279853 Negative_regulation of Gene_expression of Nipbl 1 0.51 2.37 0.19 97.32
5 INT279846 Gene_expression of Nipbl 1 0.68 11.1 0.56 97.12
6 INT73627 Binding of Fap 8 0.36 11.14 0.4 95.92
7 INT123738 Regulation of Fap 2 0.39 2.59 0.08 94.68
8 INT88949 Positive_regulation of Il12a 79 0.60 47.68 19.98 93.04
9 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77 92.76
10 INT68565 Gene_expression of Fap 14 0.57 24.39 1.14 90.48
11 INT145328 Negative_regulation of Scrib 25 0.16 26.79 2.66 88.72
12 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 86.88
13 INT256628 Regulation of Nsdhl 2 0.11 4.12 0.43 84.12
14 INT212176 Gene_expression of CEACAM5 7 0.75 6.05 0.24 80.08
15 INT115889 Binding of Fas 27 0.36 28.87 4.08 79.92
16 INT35328 Gene_expression of KRTAP19-9P 9 0.52 9.08 1.44 79.76
17 INT36287 Binding of CD4 96 0.47 58.93 11.88 78.00
18 INT279862 Binding of Nipbl 1 0.36 1.22 0.04 77.40
19 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 74.16
20 INT23647 Negative_regulation of CDA 3 0.38 1.48 0.08 74.00
21 INT99176 Positive_regulation of Fap 4 0.13 7.5 0.22 66.88
22 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 55.04
23 INT179300 Negative_regulation of TGFB1I1 1 0.06 1.92 0 49.28
24 INT18156 Gene_expression of Fap 18 0.73 27.02 1.46 46.80
25 INT242822 Transcription of Fap 1 0.18 1.2 0 36.32
26 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19 32.80
27 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 19.76
28 INT194322 Positive_regulation of CST7 1 0.32 0.39 0.17 11.60
29 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 5.00
30 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
31 INT10166 Localization of Tnf 237 0.81 153.95 88.64 5.00
32 INT86521 Gene_expression of Lpar1 167 0.78 154.61 80.35 5.00
33 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 5.00
34 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
35 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 5.00
36 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
37 INT69592 Positive_regulation of PSMD1 27 0.70 17.83 18.98 5.00
38 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33 5.00
39 INT77620 Gene_expression of Fas 146 0.78 72.4 16.61 5.00
40 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 5.00
41 INT8224 Gene_expression of CHGA 73 0.75 53.63 12.31 5.00
42 INT68960 Gene_expression of Ptger4 42 0.67 15.75 9.64 5.00
43 INT14301 Binding of CSF2 82 0.48 67.95 8.98 5.00
44 INT158796 Positive_regulation of SMUG1 67 0.70 38.97 8.98 5.00
45 INT228870 Negative_regulation of Lpar1 17 0.51 20.97 8.77 5.00
46 INT6557 Gene_expression of Eno2 65 0.77 54.42 8.17 5.00
47 INT88014 Positive_regulation of Gene_expression of Fas 29 0.50 14.84 7.47 5.00
48 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02 5.00
49 INT26585 Gene_expression of Vim 117 0.77 39.97 6 5.00
50 INT97797 Localization of TLR4 18 0.77 13.78 6 5.00
51 INT80033 Binding of FAS 37 0.48 41.19 5.67 5.00
52 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22 5.00
53 INT10504 Localization of Pla2g1b 18 0.65 8.19 5.05 5.00
54 INT78393 Gene_expression of Adm 16 0.78 8.4 4.92 5.00
55 INT111739 Negative_regulation of Npy 15 0.43 4.9 4.65 5.00
56 INT113517 Binding of Fas 16 0.37 15.86 4.62 5.00
57 INT48960 Gene_expression of SCG2 16 0.68 4.41 4.33 5.00
58 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91 5.00
59 INT94303 Gene_expression of Upf1 44 0.04 11.62 3.87 5.00
60 INT151427 Gene_expression of ADC 31 0.55 21.86 3.81 5.00
61 INT188406 Binding of Fasl 19 0.44 24.67 3.17 5.00
62 INT177586 Positive_regulation of Gene_expression of MRI1 9 0.33 4.97 2.91 5.00
63 INT134795 Positive_regulation of Scrib 30 0.22 36.91 2.81 5.00
64 INT86815 Gene_expression of Pla2g2a 18 0.55 5.72 2.59 5.00
65 INT79816 Localization of Pla2g2a 13 0.74 8.08 2.06 5.00
66 INT77523 Positive_regulation of ADC 14 0.63 13.81 1.81 5.00
67 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77 5.00
68 INT3818 Regulation of Apc 13 0.39 12.52 1.68 5.00
69 INT216123 Negative_regulation of Cd68 2 0.41 1.96 1.48 5.00
70 INT59837 Regulation of Upf1 5 0.03 1.37 1.45 5.00
71 INT103907 Negative_regulation of Upf1 15 0.37 4.3 1.4 5.00
72 INT46736 Negative_regulation of Odc1 10 0.51 7.6 1.39 5.00
73 INT108325 Gene_expression of Scrib 26 0.39 48.33 1.39 5.00
74 INT220177 Binding of Apc 21 0.37 15.34 1.37 5.00
75 INT172452 Gene_expression of Myc 121 0.78 69.56 1.36 5.00
76 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31 5.00
77 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3 5.00
78 INT139077 Negative_regulation of Ptch1 5 0.56 5.22 1.29 5.00
79 INT148121 Gene_expression of KRT8 35 0.65 29.07 1.05 5.00
80 INT135039 Gene_expression of Cd1 11 0.60 5.66 1.05 5.00
81 INT190031 Binding of Scrib 19 0.36 21.9 1.01 5.00
82 INT116797 Gene_expression of Osmr 9 0.73 1.12 1 5.00
83 INT156326 Positive_regulation of SMARCB1 20 0.67 8.77 0.97 5.00
84 INT23660 Negative_regulation of Fap 5 0.35 8.93 0.95 5.00
85 INT242134 Localization of Apc 8 0.74 4.83 0.88 5.00
86 INT95561 Negative_regulation of Vldlr 9 0.53 2.59 0.84 5.00
87 INT135299 Binding of PTCH1 10 0.48 12.16 0.84 5.00
88 INT131384 Binding of Mutyh 5 0.26 2.41 0.78 5.00
89 INT105344 Gene_expression of Cited2 5 0.78 3.65 0.76 5.00
90 INT142416 Binding of Ptch1 6 0.34 4.92 0.74 5.00
91 INT153257 Regulation of Ptch1 6 0.36 5.92 0.67 5.00
92 INT68564 Binding of Fap 6 0.32 6.75 0.65 5.00
93 INT236786 Positive_regulation of Localization of TLR4 2 0.45 1.89 0.57 5.00
94 INT65919 Gene_expression of Ptch1 11 0.75 6.47 0.56 5.00
95 INT183629 Gene_expression of Ctnnd2 14 0.75 11.78 0.48 5.00
96 INT225355 Gene_expression of Set 15 0.37 2.98 0.47 5.00
97 INT151720 Negative_regulation of Positive_regulation of Apc 3 0.37 2.15 0.46 5.00
98 INT214067 Regulation of Scrib 11 0.20 12.48 0.45 5.00
99 INT58679 Gene_expression of Odc1 13 0.78 9.55 0.45 5.00
100 INT279847 Negative_regulation of Cebpb 2 0.28 1.82 0.44 5.00
101 INT238058 Negative_regulation of Shbdp1 4 0.10 1.36 0.42 5.00
102 INT182073 Binding of APEX1 4 0.12 1.72 0.32 5.00
103 INT182465 Negative_regulation of Cd1d1 4 0.28 1.72 0.29 5.00
104 INT183055 Gene_expression of PTCH1 10 0.77 15.54 0.26 5.00
105 INT171716 Regulation of Fap 4 0.27 4.05 0.23 5.00
106 INT216124 Negative_regulation of Pcna 3 0.13 2.06 0.19 5.00
107 INT181059 Gene_expression of Rnase1 5 0.25 0.98 0.19 5.00
108 INT260174 Gene_expression of Rpe65 29 0.78 4.2 0.19 5.00
109 INT286108 Negative_regulation of Afap1 1 0.08 3.35 0.18 5.00
110 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16 5.00
111 INT212175 Positive_regulation of Gene_expression of CEACAM5 1 0.36 0.7 0.13 5.00
112 INT208551 Gene_expression of Mutyh 6 0.48 6.28 0.12 5.00
113 INT212174 Positive_regulation of CEACAM5 1 0.34 0.69 0.12 5.00
114 INT242819 Negative_regulation of Gene_expression of Apc 4 0.37 5.6 0.1 5.00
115 INT143838 Gene_expression of Pitx2 3 0.53 1.86 0.09 5.00
116 INT140494 Negative_regulation of Fap 3 0.37 2.3 0.08 5.00
117 INT213515 Binding of Shh 8 0.37 1.92 0.08 5.00
118 INT279840 Positive_regulation of Gene_expression of Nipbl 1 0.44 0.22 0.07 5.00
119 INT58681 Positive_regulation of Gene_expression of Odc1 2 0.70 1.13 0.07 5.00
120 INT205973 Binding of SHH 3 0.35 1.03 0.07 5.00
121 INT279851 Positive_regulation of Nipbl 1 0.44 0.19 0.04 5.00
122 INT286105 Positive_regulation of Mutyh 1 0.36 1.94 0.04 5.00
123 INT286102 Positive_regulation of Fap 5 0.30 8.58 0.04 5.00
124 INT194323 Transcription of CST7 1 0.48 0 0.03 5.00
125 INT279869 Negative_regulation of Nipbl 1 0.43 4.3 0.03 5.00
126 INT279854 Gene_expression of Ptx3 1 0.48 0.17 0.03 5.00
127 INT244771 Gene_expression of Satb2 4 0.68 1.27 0.03 5.00
128 INT179856 Gene_expression of Sdc1 4 0.75 3.88 0.03 5.00
129 INT286095 Gene_expression of Afap1 1 0.09 2.42 0.03 5.00
130 INT279866 Regulation of Stag1 1 0.38 0.09 0 5.00
131 INT279868 Positive_regulation of Positive_regulation of Pcdhb1 1 0.47 0.08 0 5.00
132 INT279831 Positive_regulation of Lias 1 0.01 0.26 0 5.00
133 INT279856 Regulation of Pcdhb1 1 0.42 0.89 0 5.00
134 INT279834 Negative_regulation of Pcdhb7 1 0.30 0.09 0 5.00
135 INT242821 Negative_regulation of Localization of Fap 1 0.11 1.91 0 5.00
136 INT279881 Negative_regulation of Gene_expression of PCDHB@ 1 0.05 0.09 0 5.00
137 INT279845 Regulation of Nipbl 1 0.39 0.28 0 5.00
138 INT286106 Positive_regulation of Gene_expression of Mutyh 1 0.36 0.66 0 5.00
139 INT279839 Regulation of Transcription of Pcdhb1 1 0.42 0.05 0 5.00
140 INT279841 Transcription of Nipbl 1 0.63 1.21 0 5.00
141 INT279857 Localization of Nipbl 1 0.65 0 0 5.00
142 INT279861 Positive_regulation of Gene_expression of Rnase1 1 0.15 0 0 5.00
143 INT279858 Gene_expression of Tcof1 1 0.40 0.47 0 5.00
144 INT286101 Protein_catabolism of Ctnnd2 1 0.64 1.14 0 5.00
145 INT279860 Binding of Pcdhb7 1 0.26 0.09 0 5.00
146 INT286097 Binding of Afap1 1 0.05 1.72 0 5.00
147 INT265588 Localization of Fap 4 0.47 5.67 0 5.00
148 INT242820 Localization of Fap 1 0.20 1.9 0 5.00
149 INT279832 Gene_expression of Pcdhb1 1 0.72 0.06 0 5.00
150 INT279870 Transcription of Hbb-bh1 1 0.25 0 0 5.00
151 INT161203 Gene_expression of PCSK7 6 0.65 0.92 0 5.00
152 INT279833 Transcription of Pcdhb1 1 0.67 0 0 5.00
153 INT286104 Negative_regulation of Mutyh 1 0.35 2.24 0 5.00
154 INT279882 Regulation of PCDHB@ 1 0.06 0.89 0 5.00
155 INT279864 Regulation of Ctcf 1 0.14 0.18 0 5.00
156 INT279867 Binding of Rec8 1 0.01 0.81 0 5.00
157 INT286107 Positive_regulation of Phosphorylation of Fap 1 0.30 3.5 0 5.00
158 INT256625 Negative_regulation of Ptch2 1 0.42 1.27 0 5.00
159 INT286100 Binding of Rpa3 1 0.36 0 0 5.00
160 INT286103 Regulation of Gene_expression of Fap 1 0.16 1.49 0 5.00
161 INT279849 Binding of Pds5b 1 0.32 0.93 0 5.00
162 INT256627 Regulation of Negative_regulation of Ptch2 1 0.32 1.33 0 5.00
163 INT279883 Gene_expression of PCDHB@ 1 0.10 0.19 0 5.00
164 INT301374 Localization of Stk11 1 0.23 1.58 0 5.00
165 INT279871 Negative_regulation of Transcription of Nipbl 1 0.43 1.22 0 5.00
166 INT286093 Regulation of Binding of Apc 1 0.39 1.08 0 5.00
167 INT279855 Positive_regulation of Pcdhb1 1 0.47 0.08 0 5.00
168 INT279830 Regulation of Transcription of Nipbl 1 0.39 0.62 0 5.00
169 INT201643 Binding of Pcna 2 0.36 0 0 5.00
170 INT286092 Positive_regulation of Afap1 1 0.06 2.48 0 5.00
171 INT256626 Regulation of Ptch2 1 0.28 1.11 0 5.00
172 INT279835 Regulation of Transcription of Hbb-bh1 1 0.16 0 0 5.00
173 INT279850 Gene_expression of Trps1 1 0.38 0.47 0 5.00
174 INT279837 Regulation of Gene_expression of Nipbl 1 0.39 0 0 5.00
175 INT242823 Binding of CTNND2 1 0.36 6 0 5.00
176 INT279843 Negative_regulation of Ebf1 1 0.37 0.6 0 5.00
177 INT256631 Positive_regulation of PTCH1 2 0.13 1.97 0 5.00
178 INT279865 Transcription of Ctcf 1 0.36 0 0 5.00
179 INT286099 Negative_regulation of Gene_expression of Ctnnd2 1 0.41 1.06 0 5.00
180 INT286096 Phosphorylation of Fap 1 0.49 4.87 0 5.00
181 INT279838 Protein_catabolism of Rec8 1 0.02 0.81 0 5.00
182 INT279859 Regulation of Pcdhb2 1 0.54 0 0 5.00
183 INT279863 Localization of Pds5a 1 0.47 0.93 0 5.00
184 INT279844 Localization of Pds5b 1 0.65 0.94 0 5.00
185 INT279842 Regulation of Rec8 1 0.01 0.6 0 5.00
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