D:Epiretinal Membrane

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Disease Term
Synonyms Epiretinal Membranes, Membrane Epiretinal, Membranes Epiretinal
Documents 39
Hot Single Events 19
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Epiretinal Membrane. They are ordered first by their relevance to Epiretinal Membrane and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT237748 Negative_regulation of Jak3 Negative_regulation of Positive_regulation of Stat3 1 0.25 1.01 0.22 79.60
2 INT237745 Binding of Lgals3 and Lgals3bp 1 0.24 1.36 0.28 72.48
3 INT237750 Lgals3bp Positive_regulation of Binding of Lgals3 and Lgals3 1 0.30 1.36 0.28 72.48
4 INT237752 Lgals3bp Positive_regulation of Binding of Lgals3 and Lgals3bp 1 0.26 1.36 0.28 72.48
5 INT237753 Lgals3 Positive_regulation of Binding of Lgals3 and Lgals3bp 1 0.30 1.36 0.28 72.48
6 INT237749 Prkcg Regulation of Transcription of Pcgf1 1 0.14 0.68 0.25 5.00
7 INT288026 PROC Positive_regulation of Gene_expression of VEGFA 1 0.01 0.5 0.15 5.00
8 INT237746 Prkcg Regulation of Pcgf1 1 0.14 0.34 0.12 5.00
9 INT223088 Binding of ELF3 and NAGLU 1 0.14 0.84 0.09 5.00
10 INT223089 Binding of IDS and NAGLU 1 0.26 0.72 0.09 5.00
11 INT288025 VEGFA Regulation of IL6 1 0.36 0.26 0.03 5.00
12 INT288027 VEGFA Regulation of CCL2 1 0.44 0.26 0.03 5.00
13 INT288028 VEGFA Regulation of IL8 1 0.36 0.26 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Epiretinal Membrane. They are ordered first by their pain relevance and then by number of times they were reported in Epiretinal Membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT97331 Positive_regulation of Timp1 20 0.45 13.32 8.57 99.68
2 INT297602 Positive_regulation of Tsv 3 0.07 3.36 0.33 99.36
3 INT130149 Binding of Bre 3 0.26 0.64 0.19 99.00
4 INT97394 Regulation of Stat3 6 0.41 2.52 1.34 98.60
5 INT97333 Regulation of Gene_expression of Timp1 6 0.54 4.8 1.71 98.04
6 INT55740 Gene_expression of Timp1 53 0.75 28.63 13.85 97.52
7 INT159775 Negative_regulation of Gene_expression of Timp1 9 0.37 4.36 1.08 97.52
8 INT55741 Negative_regulation of Timp1 15 0.51 8.12 4.09 97.04
9 INT29 Negative_regulation of Gast 74 0.59 24.85 24.96 95.04
10 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 93.48
11 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 90.68
12 INT129771 Regulation of SMARCB1 5 0.58 8.92 0.58 89.00
13 INT8694 Binding of Lgals3 38 0.48 14.82 8.05 87.52
14 INT97393 Localization of Stat3 11 0.75 7.33 3.01 86.24
15 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 84.00
16 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78 83.44
17 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 83.44
18 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 83.44
19 INT11679 Negative_regulation of F13A1 55 0.54 33.69 9.43 82.12
20 INT107454 Positive_regulation of Stat3 43 0.68 19.63 17.69 79.60
21 INT159060 Localization of PDR 8 0.65 10.45 0.96 79.12
22 INT288032 Negative_regulation of Localization of PDR 1 0.20 1.24 0.19 79.12
23 INT237735 Negative_regulation of Lgals3 2 0.30 1.39 0.27 77.92
24 INT158573 Negative_regulation of Jak3 3 0.43 8.2 3.99 77.52
25 INT237738 Positive_regulation of Gene_expression of Jak3 1 0.32 1.98 0.49 74.16
26 INT237739 Gene_expression of Jak3 1 0.44 1.97 0.48 73.44
27 INT237733 Binding of Lgals3bp 1 0.26 1.33 0.27 72.48
28 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 69.36
29 INT1767 Positive_regulation of PROC 83 0.67 54.14 17 68.76
30 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 68.40
31 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 68.16
32 INT80939 Positive_regulation of PDR 8 0.55 5.43 0.67 67.00
33 INT173716 Positive_regulation of Cd44 7 0.44 4.65 1.45 63.44
34 INT65245 Gene_expression of Nos3 121 0.78 98.14 41.56 60.88
35 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 54.60
36 INT273474 Positive_regulation of Gene_expression of Lefty1 1 0.01 1.61 0.26 52.92
37 INT74260 Positive_regulation of Serping1 5 0.64 6.05 0.8 52.52
38 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 51.80
39 INT76892 Gene_expression of FGFR1 45 0.69 23.6 7.56 51.80
40 INT172959 Gene_expression of Lefty1 4 0.21 5.15 0.76 51.80
41 INT67144 Gene_expression of Cd44 17 0.76 8.94 4.48 44.32
42 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 36.40
43 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 36.24
44 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 35.80
45 INT12339 Localization of IL8 437 0.81 251.87 117.39 23.80
46 INT12082 Localization of IL6 365 0.81 241.78 105.78 23.80
47 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 23.80
48 INT65698 Localization of CCL2 118 0.81 77.54 32.69 23.80
49 INT237741 Positive_regulation of Serpinf1 1 0.25 3.56 0.58 22.64
50 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27 13.52
51 INT157378 Gene_expression of PDR 14 0.53 11.46 0.64 13.52
52 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 11.00
53 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 5.00
54 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
55 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 5.00
56 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 5.00
57 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
58 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76 5.00
59 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
60 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 5.00
61 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41 5.00
62 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 5.00
63 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 5.00
64 INT64110 Positive_regulation of Gene_expression of Nos1 68 0.70 58.11 51.64 5.00
65 INT122041 Binding of Ppara 308 0.48 189.17 51.48 5.00
66 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
67 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
68 INT30 Gene_expression of Gast 158 0.78 99 41.45 5.00
69 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 5.00
70 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 5.00
71 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 5.00
72 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 5.00
73 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75 5.00
74 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67 5.00
75 INT10835 Regulation of IL8 79 0.49 53.04 24.14 5.00
76 INT4535 Localization of PROC 106 0.73 76.24 21.1 5.00
77 INT78901 Localization of CCL5 67 0.78 40.79 20.59 5.00
78 INT102545 Gene_expression of Ccr2 42 0.78 61.43 19.81 5.00
79 INT66857 Regulation of CCL2 39 0.53 28.55 18.35 5.00
80 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 5.00
81 INT69878 Positive_regulation of Gene_expression of Gtf3a 48 0.29 36.78 13.57 5.00
82 INT10585 Localization of NAGLU 53 0.80 23.32 12.75 5.00
83 INT89294 Gene_expression of Ccr3 53 0.68 43.9 12.62 5.00
84 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4 5.00
85 INT134625 Gene_expression of Kdr 116 0.71 53.13 10.09 5.00
86 INT2036 Localization of EGF 42 0.77 21.5 9.74 5.00
87 INT135407 Negative_regulation of Ccl2 33 0.57 32.74 9.45 5.00
88 INT140224 Localization of Ccl2 32 0.72 26.91 9.39 5.00
89 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37 5.00
90 INT168642 Gene_expression of Cx3cr1 15 0.77 21.73 8.1 5.00
91 INT172789 Regulation of Gene_expression of Nos3 15 0.53 16.23 7.86 5.00
92 INT157959 Binding of AQP4 32 0.48 43.44 7.44 5.00
93 INT8793 Gene_expression of H2 58 0.75 26.36 7.07 5.00
94 INT140170 Binding of Nqo1 24 0.38 36.16 6.79 5.00
95 INT194479 Phosphorylation of Ppara 47 0.81 30.36 6.6 5.00
96 INT75832 Positive_regulation of Positive_regulation of IL8 30 0.70 20.77 6.05 5.00
97 INT103847 Positive_regulation of Ccr5 11 0.55 6.04 5.79 5.00
98 INT91147 Positive_regulation of Positive_regulation of Ppara 30 0.69 19.31 5.56 5.00
99 INT15284 Positive_regulation of Lgals3 21 0.47 8.88 5.52 5.00
100 INT70193 Gene_expression of Slc6a12 10 0.78 3.73 5.39 5.00
101 INT122038 Transcription of Ppara 35 0.71 20.5 5.12 5.00
102 INT3163 Gene_expression of NAGLU 28 0.75 15.23 4.98 5.00
103 INT16214 Localization of F13A1 36 0.74 21.8 4.87 5.00
104 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79 5.00
105 INT102034 Positive_regulation of Ppard 10 0.69 3.97 3.17 5.00
106 INT76092 Localization of ISYNA1 10 0.66 7.72 3.11 5.00
107 INT105993 Gene_expression of IDS 26 0.78 10.83 2.41 5.00
108 INT168637 Negative_regulation of Cx3cr1 6 0.58 11.67 2.41 5.00
109 INT150476 Positive_regulation of ELF3 32 0.56 13.61 2.39 5.00
110 INT101516 Positive_regulation of PPARD 8 0.49 4.75 2.19 5.00
111 INT68829 Binding of ELF3 14 0.47 7.96 2 5.00
112 INT194074 Regulation of NAGLU 5 0.38 2.93 1.87 5.00
113 INT67980 Positive_regulation of Positive_regulation of CCL2 7 0.49 5.89 1.85 5.00
114 INT105248 Negative_regulation of Vegfa 8 0.47 6.19 1.61 5.00
115 INT223091 Gene_expression of ELF3 45 0.62 17.9 1.56 5.00
116 INT39969 Localization of Kcne2 4 0.61 1.11 1.56 5.00
117 INT181373 Negative_regulation of Gene_expression of Ccr2 5 0.59 5.92 1.44 5.00
118 INT228772 Positive_regulation of Localization of Ccl2 3 0.48 4.23 1.21 5.00
119 INT126040 Gene_expression of Slc15a2 10 0.67 0.67 1.19 5.00
120 INT95310 Gene_expression of Slc6a11 3 0.39 1.04 1.11 5.00
121 INT228770 Gene_expression of amd 16 0.57 21.49 1.05 5.00
122 INT200462 Binding of IDS 13 0.31 4.95 1 5.00
123 INT139863 Binding of amd 27 0.41 41.3 0.91 5.00
124 INT109983 Positive_regulation of Hspb1 7 0.66 6.66 0.72 5.00
125 INT200754 Gene_expression of Rpe 35 0.51 6.3 0.58 5.00
126 INT237744 Positive_regulation of Chi3l1 2 0.40 0.58 0.52 5.00
127 INT219292 Gene_expression of Fabp4 11 0.46 2.87 0.51 5.00
128 INT9020 Binding of Tsv 2 0.25 1.28 0.48 5.00
129 INT200435 Binding of polymerase 6 0.16 5.56 0.47 5.00
130 INT228771 Localization of C3ar1 2 0.03 2.71 0.38 5.00
131 INT145051 Regulation of Transcription of Ppara 5 0.43 2.14 0.31 5.00
132 INT237734 Transcription of Pcgf1 1 0.45 0.68 0.25 5.00
133 INT237743 Gene_expression of Dclk1 3 0.70 17.9 0.24 5.00
134 INT200555 Negative_regulation of Gene_expression of Kdr 8 0.38 3.78 0.19 5.00
135 INT5433 Regulation of polymerase 8 0.03 4.2 0.15 5.00
136 INT192194 Positive_regulation of FBXW11 3 0.34 0.84 0.14 5.00
137 INT237740 Negative_regulation of Dclk1 1 0.32 0.65 0.13 5.00
138 INT237736 Positive_regulation of Jak3 1 0.37 0.33 0.12 5.00
139 INT237737 Positive_regulation of Lgals3bp 1 0.35 0.33 0.12 5.00
140 INT237742 Positive_regulation of Lama5 1 0.38 0.33 0.12 5.00
141 INT185394 Binding of PVRL1 5 0.14 2.94 0.09 5.00
142 INT346651 Gene_expression of Tsv 1 0.10 0.59 0.06 5.00
143 INT212586 Phosphorylation of polymerase 3 0.08 2.64 0 5.00
144 INT308254 Negative_regulation of Binding of PVRL1 1 0.01 1.02 0 5.00
145 INT308253 Regulation of Phosphorylation of polymerase 1 0.01 1.19 0 5.00
146 INT223092 Negative_regulation of AP2S1 1 0.01 0.72 0 5.00
147 INT223093 Phosphorylation of NAGLU 1 0.45 0.95 0 5.00
148 INT86569 Gene_expression of AP2S1 2 0.15 0.55 0 5.00
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