D:Esophageal Cancer

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pChart

Disease Term
Synonyms Cancer Esophageal, CANCER ESOPHAGUS, CANCER OF ESOPHAGUS, Cancer Of The Esophagus, Cancers Esophageal, Cancers Esophagus, Esophageal Cancers, Esophageal Carcinoma, Esophageal Carcinomas, Esophageal Dysplasia, ESOPHAGEAL HYPERPLASIA
Documents 1232
Hot Single Events 200
Hot Interactions 14

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Esophageal Cancer. They are ordered first by their relevance to Esophageal Cancer and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT102625 IL6 Regulation of Gene_expression of PTGS2 1 0.11 0.29 0.24 99.60
2 INT102620 PTAFR Regulation of Gene_expression of IL6 1 0.24 0.29 0.24 99.60
3 INT102617 PTAFR Regulation of Gene_expression of PTGS2 1 0.12 0.29 0.24 99.60
4 INT331928 Negative_regulation of Cpox Negative_regulation of VEGFA 1 0.01 0.97 0.47 99.48
5 INT102622 PTAFR Regulation of IL6 1 0.24 0.29 0.24 98.36
6 INT102621 IL6 Regulation of Gene_expression of CPOX 1 0.13 0.78 0.25 94.44
7 INT102618 PTAFR Regulation of Gene_expression of CPOX 1 0.08 0.38 0 94.44
8 INT260382 Das Negative_regulation of Gene_expression of IGLL1 1 0.00 0.94 0 88.48
9 INT200097 Negative_regulation of Binding of Il1a and Jun 1 0.00 2.76 0.77 87.60
10 INT200093 Binding of Il1a and Jun 1 0.00 2.64 0.76 87.60
11 INT200096 Negative_regulation of Il1a Negative_regulation of Gene_expression of Ptgs2 1 0.00 1.45 0.39 87.60
12 INT238802 Binding of Ager and Renbp 6 0.02 6.46 0.22 87.52
13 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78 86.16
14 INT183721 HPN Positive_regulation of MYO7A 1 0.02 1.55 0 80.24
15 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 78.56
16 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 77.76
17 INT96417 CYC1 Positive_regulation of Casp9 1 0.02 0.96 0.17 75.00
18 INT96416 CYC1 Positive_regulation of Casp3 1 0.02 0.96 0.17 75.00
19 INT119045 HIF1A Regulation of Regulation of TP53 1 0.09 1.06 0 75.00
20 INT119046 HIF1A Regulation of TP53 1 0.05 1.06 0 75.00
21 INT119044 HIF1A Regulation of TCEAL1 1 0.02 1.06 0 75.00
22 INT119047 HIF1A Regulation of Regulation of TCEAL1 1 0.08 1.06 0 75.00
23 INT286650 Binding of IGHG3 and OLR1 1 0.01 0.42 0 72.16
24 INT236246 Binding of CD8A and Birc5 1 0.04 1.34 0 71.04
25 INT83425 Binding of CD40LG and IGHG3 11 0.21 4.56 2.09 70.24
26 INT286653 Binding of CD40LG and OLR1 1 0.08 0.41 0 70.24
27 INT102627 IL6 Positive_regulation of Gene_expression of CPOX 1 0.20 0.34 0 65.44
28 INT266422 HMGB1 Positive_regulation of Binding of Ager 1 0.01 0.92 0.16 59.36
29 INT266376 Binding of Ager and Itgam 1 0.00 2.31 0.54 58.76
30 INT102623 Negative_regulation of PRKCA Negative_regulation of Gene_expression of CPOX 1 0.09 0.12 0 58.64
31 INT323352 Binding of F8 and VWF 5 0.08 2.22 0.33 58.56
32 INT343794 Binding of F8 and PTPRC 1 0.00 0.69 0.09 58.20
33 INT182494 TNF Positive_regulation of OLR1 1 0.05 2.51 0.13 54.60
34 INT182493 HGS Positive_regulation of OLR1 1 0.00 2.51 0.13 54.60
35 INT253021 PTTG1 Regulation of Gene_expression of Fgf2 1 0.04 0.35 0 52.48
36 INT102626 PTAFR Positive_regulation of Gene_expression of CPOX 1 0.11 0.1 0 52.20
37 INT182491 OLR1 Positive_regulation of HGS 1 0.00 1.22 0.07 51.20
38 INT102624 IL6 Positive_regulation of PTAFR 1 0.21 0.05 0 50.60
39 INT343792 Binding of TCF21 and CORO7 1 0.01 0.51 0.07 50.00
40 INT200517 Lar Regulation of Gene_expression of Crp 1 0.01 0.1 0 50.00
41 INT182488 OLR1 Positive_regulation of OLR1 Positive_regulation of Gene_expression of AGTR1 1 0.00 1.27 0.07 48.28
42 INT139538 Binding of CD34 and KIT 2 0.39 2.73 0.14 47.20
43 INT187575 TP53 Regulation of Gene_expression of Birc5 1 0.05 1.1 0 45.84
44 INT187576 BAX Regulation of Gene_expression of Birc5 1 0.06 1.1 0 45.56
45 INT286651 OLR1 Positive_regulation of PRKCA 1 0.14 0.5 0 45.20
46 INT241262 TP53 Positive_regulation of Gene_expression of OPCML 1 0.31 1.22 0 40.52
47 INT252895 PTTG1 Regulation of Gene_expression of VEGFA 1 0.03 0.15 0 36.44
48 INT241256 TP53 Regulation of OPCML 1 0.12 1.31 0 33.20
49 INT187574 Binding of TP53 and Birc5 1 0.04 1.27 0 33.08
50 INT214437 NCAM1 Regulation of CHGA 1 0.05 1.21 0.07 27.40
51 INT252902 PTTG1 Regulation of MMP2 1 0.01 1.5 0.14 24.36
52 INT331924 Binding of Arg1 and Actvty1 1 0.03 1.11 0.05 20.76
53 INT252901 PTTG1 Regulation of Gene_expression of TSC1 1 0.00 1.61 0.13 19.28
54 INT253016 Binding of PTTG1 and Id3 1 0.04 0.07 0 16.32
55 INT253020 Pttg1 Negative_regulation of THBS1 1 0.03 0.16 0 16.08
56 INT331923 Actvty1 Positive_regulation of Ptger2 1 0.01 0.99 0.04 13.60
57 INT253003 Pttg1 Regulation of Gene_expression of Id3 1 0.08 0.07 0 12.44
58 INT331927 Ptger2 Positive_regulation of Arg1 1 0.06 1.8 0.42 12.28
59 INT354925 ALB Positive_regulation of ALPP 1 0.34 1.69 0.09 11.00
60 INT253008 PTTG1 Regulation of Gene_expression of Id3 1 0.03 0.2 0 8.60
61 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
62 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
63 INT266391 Binding of Ager and S100a1 1 0.01 5.63 1.69 5.00
64 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68 5.00
65 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57 5.00
66 INT209409 Binding of CALM1 and NHS 2 0.27 0.58 1.32 5.00
67 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27 5.00
68 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18 5.00
69 INT306823 Binding of E2F4 and GOPC 1 0.06 0.23 0.91 5.00
70 INT306831 Positive_regulation of Binding of E2F4 and NOLC1 1 0.10 0.46 0.85 5.00
71 INT306826 Binding of E2F4 and NOLC1 1 0.08 0.41 0.84 5.00
72 INT266408 Binding of HMGB1 and Ager 1 0.01 2.57 0.76 5.00
73 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 5.00
74 INT244320 Tlr4 Positive_regulation of Aliq1 3 0.04 4.51 0.64 5.00
75 INT181084 Binding of S100a8 and S100a9 6 0.42 2.91 0.62 5.00
76 INT327167 RETNLB Regulation of IL6 1 0.00 2.26 0.6 5.00
77 INT327164 RETNLB Regulation of TNF 1 0.00 2.27 0.6 5.00
78 INT327165 RETNLB Regulation of Gene_expression of CRP 1 0.01 2.25 0.59 5.00
79 INT327166 RETNLB Regulation of IL36RN 1 0.00 2.25 0.59 5.00
80 INT351076 IK Positive_regulation of Gene_expression of Ucp3 1 0.00 0.8 0.58 5.00
81 INT190702 CD40 Positive_regulation of Gene_expression of F3 1 0.00 1.4 0.55 5.00
82 INT266381 Positive_regulation of Ager Positive_regulation of Nfkb1 1 0.00 0.77 0.55 5.00
83 INT306828 Binding of E2F2 and E2F3 1 0.20 0.15 0.46 5.00
84 INT306824 Binding of E2F1 and E2F2 1 0.15 0.15 0.46 5.00
85 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45 5.00
86 INT182489 Gene_expression of AGTR2 Positive_regulation of Gene_expression of AGTR1 1 0.26 0.92 0.4 5.00
87 INT266393 Binding of Ager and Fn1 1 0.00 0.82 0.39 5.00
88 INT266382 Binding of Col4a1 and Fn1 1 0.00 0.82 0.39 5.00
89 INT266397 Binding of Ager and Col4a1 1 0.00 0.81 0.38 5.00
90 INT182497 IL1B Regulation of Localization of GH1 1 0.00 0.84 0.38 5.00
91 INT331925 Ptger2 Positive_regulation of Actvty1 1 0.01 0.77 0.38 5.00
92 INT182492 IL1B Regulation of Gene_expression of IGF1 1 0.01 0.83 0.38 5.00
93 INT266419 HMGB1 Positive_regulation of Ager 1 0.01 1.37 0.37 5.00
94 INT306830 E2F2 Regulation of C1orf61 1 0.02 0.48 0.36 5.00
95 INT306822 Binding of E2F2 and GOPC 1 0.05 0.53 0.35 5.00
96 INT266402 Binding of S100P and Ager 1 0.00 2.25 0.35 5.00
97 INT266383 Binding of Ager and S100b 1 0.01 3.48 0.33 5.00
98 INT266375 S100b Positive_regulation of Ager 1 0.02 1.8 0.31 5.00
99 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3 5.00
100 INT101810 Binding of NFE2L2 and KEAP1 7 0.53 4.12 0.29 5.00
101 INT182499 Binding of AGTR1 and AGTR2 3 0.20 2.79 0.28 5.00
102 INT292154 TNIP1 Positive_regulation of HIVEP1 1 0.01 0.97 0.27 5.00
103 INT266421 Binding of HMGB1 and Il1 1 0.02 0.37 0.24 5.00
104 INT354926 IL6 Regulation of Gene_expression of ALB 1 0.14 1.3 0.23 5.00
105 INT173120 Binding of PPARA and NR1H4 8 0.09 2.79 0.23 5.00
106 INT354924 IL6 Positive_regulation of Gene_expression of ALB 1 0.26 1.3 0.23 5.00
107 INT266418 Binding of HMGB1 and Tlr4 1 0.09 0.37 0.23 5.00
108 INT266405 S100b Positive_regulation of Gene_expression of TFAM 1 0.00 1.02 0.21 5.00
109 INT266380 Binding of Tlr2 and Il1 1 0.01 0.76 0.21 5.00
110 INT182606 Binding of MSH2 and MSH3 1 0.12 1.4 0.21 5.00
111 INT266401 S100b Positive_regulation of S100b Positive_regulation of Ager 1 0.01 0.96 0.21 5.00
112 INT266423 Binding of HMGB1 and Mapk3 1 0.04 0.9 0.2 5.00
113 INT266410 Binding of HMGB1 and Mapk14 1 0.03 0.91 0.2 5.00
114 INT266416 Binding of HMGB1 and Mapk1 1 0.06 0.9 0.2 5.00
115 INT266414 Binding of HMGB1 and Mapk8 1 0.03 0.91 0.2 5.00
116 INT266404 Binding of HMGB1 and Thbd 1 0.06 0.3 0.2 5.00
117 INT75057 Binding of POMC and Msx1 2 0.39 0.6 0.2 5.00
118 INT327112 HCCS Positive_regulation of Gene_expression of SLCO1B3 1 0.03 0.65 0.19 5.00
119 INT296036 IL6 Positive_regulation of IL17A 1 0.04 0.05 0.17 5.00
120 INT296037 TGFB1 Positive_regulation of IL17A 1 0.02 0 0.17 5.00
121 INT296081 Binding of FOXP3 and Gtf3a 1 0.00 1.16 0.16 5.00
122 INT266417 Binding of TGM2 and S100a11 1 0.01 0.86 0.16 5.00
123 INT296030 Binding of NFKB1 and FOXP3 1 0.17 1.18 0.16 5.00
124 INT263901 Binding of Ighg1 and Slc3a2 1 0.00 0.89 0.16 5.00
125 INT301121 Tgm7 Regulation of Gene_expression of Mmp2 1 0.52 2.53 0.16 5.00
126 INT296078 Binding of NFKB1 and Gtf3a 1 0.00 1.18 0.16 5.00
127 INT266412 Binding of S100A12 and Ager 1 0.01 1.03 0.15 5.00
128 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15 5.00
129 INT296082 Binding of Rel and FOXP3 1 0.35 1.14 0.15 5.00
130 INT266413 Positive_regulation of Binding of HMGB1 and Col4a1 1 0.02 1.05 0.14 5.00
131 INT266411 Binding of HMGB1 and Col4a1 1 0.01 1.05 0.14 5.00
132 INT213749 NHS Positive_regulation of Localization of CALM1 1 0.28 0.58 0.14 5.00
133 INT253009 Igf1 Regulation of PTTG1 1 0.03 0.44 0.13 5.00
134 INT296031 Negative_regulation of TGFB1 Regulation of IL10 1 0.01 1.01 0.13 5.00
135 INT175398 Binding of ERBB2 and VEGFA 2 0.16 1.34 0.13 5.00
136 INT253015 Egf Regulation of PTTG1 1 0.02 0.44 0.13 5.00
137 INT266403 Negative_regulation of Binding of S100P and Ager 1 0.00 0.74 0.13 5.00
138 INT296027 TGFB1 Regulation of TH1L 1 0.02 1 0.13 5.00
139 INT175401 Binding of EGFR and VEGFA 2 0.13 1.49 0.13 5.00
140 INT296079 IL17A Negative_regulation of Positive_regulation of Gtf3a 1 0.00 0.77 0.13 5.00
141 INT173200 PPA1 Positive_regulation of Myc 1 0.08 0.5 0.12 5.00
142 INT296080 TGFB1 Regulation of Hand2 1 0.01 1 0.12 5.00
143 INT173121 PPARA Negative_regulation of Gene_expression of CYP7A1 1 0.18 0.48 0.12 5.00
144 INT173129 PTGS2 Regulation of IER3 1 0.01 0.36 0.12 5.00
145 INT296029 Binding of HLA-DQA2 and LAG3 1 0.02 0.43 0.12 5.00
146 INT296028 TGFB1 Regulation of IL10 1 0.01 1 0.12 5.00
147 INT173122 PPA1 Positive_regulation of HRAS 1 0.08 0.5 0.12 5.00
148 INT173125 PPA1 Positive_regulation of JUN 1 0.06 0.5 0.12 5.00
149 INT182496 AGT Positive_regulation of Phosphorylation of STAT3 1 0.03 0.79 0.12 5.00
150 INT173119 PPA1 Regulation of IER3 1 0.00 0.36 0.12 5.00
151 INT296040 IL17A Regulation of TH1L 1 0.07 0.7 0.12 5.00
152 INT182607 Binding of MLH1 and MSH3 1 0.04 0.81 0.11 5.00
153 INT296038 TGFB1 Positive_regulation of Gene_expression of IL23R 1 0.02 0.05 0.11 5.00
154 INT266384 Binding of Ager and S100a6 1 0.01 1.32 0.11 5.00
155 INT296032 IL6 Positive_regulation of Gene_expression of IL23R 1 0.02 0.05 0.11 5.00
156 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1 5.00
157 INT173126 CYP8B1 Positive_regulation of PPARA 1 0.25 0.39 0.1 5.00
158 INT266385 S100a6 Positive_regulation of Ager 1 0.01 0.84 0.1 5.00
159 INT266373 Itgam Positive_regulation of Ager 1 0.01 0.84 0.1 5.00
160 INT266396 Binding of Ager and S100a4 1 0.01 0.59 0.1 5.00
161 INT173124 PPA1 Regulation of ZFP37 1 0.00 0.44 0.1 5.00
162 INT127143 Binding of IL6 and TGFB1 2 0.01 0.16 0.08 5.00
163 INT296041 Binding of TGFB1 and IL21 1 0.01 0.05 0.08 5.00
164 INT296026 Binding of FOXP3 and IL17RB Negative_regulation of Gene_expression of IL7R 1 0.01 0.63 0.08 5.00
165 INT296035 IL21 Positive_regulation of Gene_expression of IL23R 1 0.01 0.05 0.08 5.00
166 INT173130 Binding of INS and PPARA 2 0.04 1.8 0.08 5.00
167 INT185279 Binding of CCND1 and CDK4 4 0.13 2.05 0.08 5.00
168 INT266394 Binding of S100a4 and Trp53 1 0.03 0.59 0.08 5.00
169 INT296039 Binding of FOXP3 and IL17RB 1 0.01 0.63 0.08 5.00
170 INT296034 FOXP3 Negative_regulation of Gene_expression of IL7R 1 0.10 0.63 0.08 5.00
171 INT185278 Binding of CCND1 and CDK6 3 0.13 1.62 0.08 5.00
172 INT352217 Tlr4 Positive_regulation of Binding of Tbce 1 0.03 0.8 0.07 5.00
173 INT266389 Binding of C2 and S100a6 1 0.04 0.5 0.07 5.00
174 INT266390 Binding of S100a6 and Trp53 1 0.04 0.51 0.07 5.00
175 INT301122 Tgm7 Negative_regulation of Akt1 1 0.38 2.78 0.07 5.00
176 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07 5.00
177 INT349886 Negative_regulation of Binding of Pcyt1a and Twist1 1 0.02 1.21 0.06 5.00
178 INT266388 S100a6 Negative_regulation of Mapk8 1 0.03 0.49 0.06 5.00
179 INT349887 Binding of Pcyt1a and Twist1 1 0.02 1.21 0.06 5.00
180 INT266374 Binding of S100a1 and S100a9 1 0.09 0.17 0.05 5.00
181 INT278454 CSF2 Regulation of Hand2 1 0.02 0.66 0.05 5.00
182 INT266387 Binding of S100a1 and S100a8 1 0.09 0.17 0.05 5.00
183 INT253023 Binding of PTTG1 and Myc 1 0.16 0.22 0.04 5.00
184 INT301128 Binding of Tgm7 and Gm9662 1 0.01 0.12 0.04 5.00
185 INT352216 Binding of Tlr4 and Tbce 1 0.01 0.3 0.04 5.00
186 INT266379 S100a8 Positive_regulation of Ager 1 0.01 0.3 0.04 5.00
187 INT252897 Binding of PTTG1IP and PTTG1 1 0.04 0.15 0.04 5.00
188 INT252892 PTTG1IP Regulation of PTTG1 1 0.05 0.49 0.04 5.00
189 INT266372 Binding of S100a1 and S100a4 1 0.11 0.15 0.04 5.00
190 INT178503 Binding of Cd36 and ecs 1 0.01 0.34 0.04 5.00
191 INT266392 S100a9 Positive_regulation of Ager 1 0.01 0.3 0.04 5.00
192 INT178501 Angpt1 Positive_regulation of Tek 1 0.06 0.78 0.04 5.00
193 INT253017 PTTG1IP Regulation of Regulation of Fgf2 1 0.03 0.49 0.04 5.00
194 INT185756 Binding of ITIH4 and Cd4 2 0.05 1.22 0.04 5.00
195 INT301130 Binding of VEGFA and Mmp2 1 0.03 1.33 0.03 5.00
196 INT301126 Tgm7 Regulation of Localization of Mmp2 1 0.38 0.2 0.03 5.00
197 INT173199 CNOT4 Regulation of Regulation of Myc 1 0.01 0.66 0.03 5.00
198 INT178502 Col18a1 Negative_regulation of ecs 1 0.01 0.52 0.03 5.00
199 INT253010 Binding of PTTG1 and Fgf2 1 0.07 0.51 0.03 5.00
200 INT236235 HLA-A Positive_regulation of CD8A 1 0.01 1 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Esophageal Cancer. They are ordered first by their pain relevance and then by number of times they were reported in Esophageal Cancer. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT230119 Positive_regulation of HIST4H4 1 0.20 0.65 0 100.00
2 INT69727 Gene_expression of QPCT 18 0.65 5.45 3.05 100.00
3 INT246524 Binding of QPCT 4 0.05 3.65 0.72 100.00
4 INT72782 Positive_regulation of HCC 41 0.40 63.74 2.46 100.00
5 INT178962 Gene_expression of Oca2 15 0.19 5.15 0.38 100.00
6 INT190454 Regulation of NANOG 2 0.30 1.29 0.17 100.00
7 INT252954 Positive_regulation of Gene_expression of Oca2 2 0.03 2.21 0 100.00
8 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 99.98
9 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 99.98
10 INT69992 Negative_regulation of Hmox2 93 0.50 49.01 44.07 99.92
11 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 99.84
12 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 99.84
13 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66 99.84
14 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 99.84
15 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 99.84
16 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46 99.84
17 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07 99.84
18 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 99.84
19 INT306952 Regulation of NAMPT 4 0.53 8.52 0.33 99.80
20 INT106952 Positive_regulation of NPC1 23 0.43 22.9 0.94 99.80
21 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67 99.78
22 INT7336 Positive_regulation of VIP 60 0.70 24.2 19.62 99.76
23 INT89606 Positive_regulation of Gene_expression of ALOX15 9 0.70 8.34 3.76 99.74
24 INT93079 Positive_regulation of ALOX15 8 0.70 12.46 6.22 99.72
25 INT23589 Positive_regulation of CALCR 9 0.67 6.73 1.25 99.72
26 INT66209 Negative_regulation of Localization of NFKB1 23 0.58 8.2 5.31 99.70
27 INT18523 Negative_regulation of ALOX15 15 0.59 14.2 5.92 99.68
28 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32 99.64
29 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 99.62
30 INT148274 Negative_regulation of Regulation of PTGS2 1 0.01 0.47 0.19 99.62
31 INT89607 Negative_regulation of Negative_regulation of ALOX15 3 0.43 2.08 0.68 99.60
32 INT49108 Gene_expression of TP53TG3 6 0.43 6.02 0.35 99.60
33 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.60
34 INT10506 Gene_expression of PTAFR 86 0.76 37.57 28.58 99.60
35 INT71002 Gene_expression of ALOX15 21 0.78 21.16 6.37 99.58
36 INT239093 Gene_expression of PTTG1 84 0.65 83.94 1.87 99.56
37 INT132513 Positive_regulation of OPCML 4 0.50 7.24 0.27 99.52
38 INT132515 Negative_regulation of OPCML 3 0.51 10.15 0.35 99.52
39 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 99.48
40 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 99.48
41 INT224366 Gene_expression of Ager 111 0.77 125.37 8.49 99.44
42 INT39733 Localization of NFKB1 59 0.79 22.76 13.99 99.42
43 INT25517 Regulation of NFKB1 41 0.61 22.28 16.09 99.42
44 INT94438 Gene_expression of OLR1 86 0.78 80.38 11.03 99.28
45 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.28
46 INT230112 Transcription of HIST4H4 1 0.28 0.53 0 99.20
47 INT230115 Positive_regulation of Transcription of HIST4H4 1 0.20 0.53 0 99.20
48 INT39406 Positive_regulation of OLR1 45 0.70 37.8 7.72 99.12
49 INT65057 Regulation of Nfkb1 28 0.47 16.48 11.62 99.10
50 INT70566 Protein_catabolism of SFTPA1 3 0.20 3.31 1.47 99.10
51 INT120164 Gene_expression of OPCML 47 0.77 36.89 0.94 99.02
52 INT89605 Negative_regulation of Gene_expression of ALOX15 8 0.59 4.03 0.61 99.00
53 INT52695 Regulation of Ptgs2 20 0.42 8.72 5.71 99.00
54 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95 98.84
55 INT21032 Gene_expression of Adh1 23 0.78 22.1 6.14 98.84
56 INT21631 Positive_regulation of Gene_expression of Adh1 4 0.70 12.56 0.39 98.84
57 INT38576 Transcription of Adh1 1 0.44 0.26 0.3 98.84
58 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85 98.68
59 INT219964 Regulation of SPAG9 1 0.11 1.04 0.13 98.66
60 INT197765 Gene_expression of Sln 26 0.58 12.11 0.45 98.64
61 INT263915 Binding of SLN 2 0.12 0.81 0 98.64
62 INT210392 Regulation of PDGFA 10 0.36 11.41 1.12 98.62
63 INT266556 Positive_regulation of AMH 9 0.70 4.33 0.82 98.56
64 INT294074 Regulation of Positive_regulation of AMH 1 0.02 0.9 0 98.56
65 INT300373 Regulation of C2orf40 1 0.02 1.34 0 98.52
66 INT64171 Regulation of CPOX 109 0.36 55.36 32.96 98.40
67 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95 98.40
68 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93 98.28
69 INT96214 Gene_expression of TCEAL1 19 0.63 16.99 1.66 98.18
70 INT182990 Positive_regulation of Gene_expression of RARA 5 0.40 3.45 0 98.16
71 INT10374 Gene_expression of RARA 39 0.75 22.59 4.28 98.16
72 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2 98.12
73 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 98.04
74 INT127273 Gene_expression of AMH 24 0.78 9.53 0.47 98.00
75 INT72219 Gene_expression of METTL3 45 0.24 9.58 7.61 97.84
76 INT213683 Positive_regulation of FAM168A 1 0.03 2.45 0.1 97.84
77 INT300366 Regulation of MIR203 1 0.09 1.34 0 97.80
78 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 97.68
79 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 97.64
80 INT94189 Positive_regulation of FUT3 11 0.31 6.61 1.5 97.20
81 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 97.08
82 INT118124 Binding of USE1 24 0.16 16.64 5.44 97.04
83 INT213679 Positive_regulation of Transcription of CALCR 1 0.30 1.37 0.04 96.96
84 INT79355 Positive_regulation of Lar 2 0.40 3.46 1.74 96.84
85 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45 96.72
86 INT119048 Negative_regulation of Gene_expression of HIF1A 10 0.57 9.23 1.5 96.72
87 INT119051 Negative_regulation of Gene_expression of TCEAL1 3 0.35 2.01 0.34 96.72
88 INT301117 Gene_expression of Tcf12 2 0.42 1.42 0 96.72
89 INT61469 Transcription of CALCR 3 0.43 1.37 0.04 96.64
90 INT191145 Positive_regulation of Gene_expression of Atp8a1 14 0.67 5.24 1.02 96.60
91 INT235659 Gene_expression of EFNA1 1 0.45 22.92 0.06 96.32
92 INT17848 Binding of PTGS2 70 0.46 32.1 20.6 96.32
93 INT235656 Positive_regulation of Gene_expression of EFNA1 1 0.40 8.86 0 96.32
94 INT119049 Negative_regulation of TCEAL1 3 0.15 2.29 0.28 96.28
95 INT214692 Negative_regulation of Gene_expression of FUT3 3 0.24 2.2 0.17 96.28
96 INT213680 Negative_regulation of Gene_expression of FAM168A 1 0.03 0.81 0 96.24
97 INT23401 Gene_expression of HLA-DOA 91 0.30 38.21 5.52 96.08
98 INT170455 Gene_expression of Atp8a1 66 0.75 24.63 3.94 96.08
99 INT191159 Gene_expression of GAGE3 1 0.01 0.92 0 96.08
100 INT213677 Gene_expression of FAM168A 1 0.04 0.81 0 96.04
101 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 95.96
102 INT325168 Negative_regulation of EXOC7 1 0.01 1.42 0 95.96
103 INT210 Positive_regulation of Sln 10 0.43 4.06 0.49 95.88
104 INT1214 Gene_expression of PGE 70 0.72 29.07 16.22 95.84
105 INT83891 Gene_expression of FUT3 20 0.61 10.49 1.41 95.84
106 INT235660 Gene_expression of EPHA2 27 0.75 23.46 0.4 95.76
107 INT235655 Positive_regulation of Gene_expression of EPHA2 14 0.67 13.48 0.35 95.76
108 INT16656 Negative_regulation of Gene_expression of YY1 8 0.57 2.62 2.12 95.68
109 INT292207 Negative_regulation of Gene_expression of TFAP2A 1 0.05 1.2 0.27 95.68
110 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 95.56
111 INT112364 Negative_regulation of HIF1A 22 0.57 16.95 2.13 95.56
112 INT279213 Positive_regulation of Binding of ERBB2 2 0.46 2.29 0 95.44
113 INT266931 Positive_regulation of Binding of EGFR 6 0.50 5.44 0 95.44
114 INT80300 Gene_expression of TFAP2A 5 0.54 2.76 0.59 95.32
115 INT294140 Positive_regulation of CIITA 2 0.38 2.24 0.24 95.28
116 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42 95.28
117 INT118286 Binding of EFNA1 3 0.21 4.95 1.55 95.28
118 INT235654 Binding of EPHA2 5 0.36 4.26 0 95.28
119 INT184529 Negative_regulation of SMUG1 8 0.49 7.06 1.46 95.24
120 INT214712 Negative_regulation of Positive_regulation of SMUG1 2 0.36 2.2 0.21 95.24
121 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 95.20
122 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 95.12
123 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 95.12
124 INT11154 Binding of EGFR 149 0.48 96.23 6.29 95.12
125 INT52962 Binding of ERBB2 77 0.47 50.03 1.49 95.12
126 INT48728 Negative_regulation of IGFBP3 28 0.59 14.84 1.21 95.04
127 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16 94.96
128 INT91122 Localization of CAT 6 0.78 4.13 1.19 94.96
129 INT213676 Negative_regulation of Gene_expression of TYMS 2 0.08 1.95 1.83 94.92
130 INT134974 Negative_regulation of Gene_expression of Ts1 2 0.31 1.34 0.09 94.92
131 INT182972 Gene_expression of HIST4H4 3 0.24 2.69 0 94.64
132 INT230114 Gene_expression of AADAC 1 0.02 0.85 0 94.64
133 INT158796 Positive_regulation of SMUG1 67 0.70 38.97 8.98 94.48
134 INT49660 Positive_regulation of EGR1 54 0.69 32.17 9.89 94.16
135 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 94.08
136 INT21632 Positive_regulation of Adh1 32 0.70 15.67 11.65 93.80
137 INT213681 Gene_expression of TYMS 9 0.33 8.96 2.45 93.80
138 INT92426 Gene_expression of Ts1 10 0.58 6.14 0.59 93.80
139 INT53343 Positive_regulation of NAMPT 13 0.60 10.94 1.58 93.68
140 INT300362 Positive_regulation of MIR203 1 0.15 1.37 0 93.60
141 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41 93.60
142 INT49803 Negative_regulation of MUC1 37 0.58 26.37 2.06 93.52
143 INT72220 Negative_regulation of METTL3 6 0.10 1.76 0.88 93.52
144 INT246514 Negative_regulation of NAMPT 4 0.51 2.98 0.37 93.52
145 INT213682 Positive_regulation of Gene_expression of TBK1 2 0.21 2.18 0.04 93.44
146 INT92335 Gene_expression of TBK1 11 0.28 8.98 3 93.44
147 INT182440 Gene_expression of CCNE2 39 0.53 22.07 7.44 93.28
148 INT201466 Positive_regulation of Gene_expression of CCNE2 13 0.20 8.62 1.26 93.28
149 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 93.24
150 INT111401 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 134 0.61 34.87 20.15 93.24
151 INT300379 Positive_regulation of MIR205 1 0.11 1.36 0 93.12
152 INT6810 Gene_expression of ENO2 70 0.78 54.8 8.35 92.96
153 INT20632 Gene_expression of TNC 72 0.78 30.43 13.16 92.96
154 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 92.80
155 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 92.72
156 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95 92.72
157 INT133567 Regulation of IL18 11 0.50 9.54 2.31 92.56
158 INT294082 Positive_regulation of CORO7 5 0.39 3.14 0.22 92.56
159 INT7383 Localization of VIP 53 0.81 17.7 22.65 92.48
160 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01 92.36
161 INT90094 Gene_expression of Cytl1 14 0.75 12.75 2.81 92.36
162 INT34085 Negative_regulation of Gene_expression of PGE 16 0.35 4.9 3.76 92.32
163 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 92.24
164 INT68443 Positive_regulation of METTL3 9 0.12 3.54 2.39 92.00
165 INT38575 Negative_regulation of Positive_regulation of Adh1 2 0.37 0.33 0.39 91.76
166 INT224367 Negative_regulation of Ager 15 0.46 25.57 0.78 91.76
167 INT230108 Localization of HIST4H4 2 0.40 1.07 0 91.68
168 INT86725 Positive_regulation of GSPT2 1 0.01 0.66 0.08 91.60
169 INT81197 Transcription of T2 2 0.17 1.37 0.21 91.52
170 INT260372 Transcription of Das 2 0.09 1.6 0.19 91.52
171 INT117145 Negative_regulation of Gene_expression of Thbs1 11 0.43 5.67 0.57 91.32
172 INT200738 Gene_expression of HIST2H4A 7 0.18 4.65 0.91 91.16
173 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 91.12
174 INT117142 Gene_expression of Thbs1 58 0.72 45.02 6.51 91.00
175 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 90.96
176 INT4598 Negative_regulation of Adh1 15 0.54 4.69 5.33 90.80
177 INT207449 Negative_regulation of OLR1 23 0.42 17.17 3.37 90.72
178 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 90.56
179 INT5285 Regulation of Gene_expression of HLA-B 4 0.41 3.39 0.68 90.56
180 INT102891 Positive_regulation of AGTR1 31 0.67 30.57 5.29 90.36
181 INT106381 Negative_regulation of CEACAM7 8 0.38 7.45 0.5 90.16
182 INT182312 Positive_regulation of Gene_expression of Birc5 26 0.69 25.3 2.32 89.92
183 INT114953 Gene_expression of NR1H4 23 0.29 16.58 2.02 89.80
184 INT4047 Binding of F13A1 105 0.43 66.54 11.81 89.60
185 INT15968 Negative_regulation of Sln 6 0.37 3.03 0.32 89.56
186 INT120767 Negative_regulation of Gene_expression of GSTP1 3 0.42 1.15 0.09 89.56
187 INT1922 Positive_regulation of CEACAM7 32 0.70 33.31 2.72 89.52
188 INT66869 Negative_regulation of EDF1 3 0.38 2.02 0.13 89.48
189 INT22815 Positive_regulation of RB1 20 0.49 14.58 1.26 89.28
190 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51 89.28
191 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 89.20
192 INT87406 Gene_expression of GSTP1 16 0.77 11.37 0.35 89.20
193 INT116540 Binding of Twist1 35 0.48 16.32 2.85 89.08
194 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34 88.96
195 INT139108 Gene_expression of Hgd 3 0.38 4.69 0.6 88.80
196 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 88.72
197 INT191143 Regulation of Gene_expression of Atp8a1 3 0.60 0.94 0 88.72
198 INT189948 Gene_expression of Pttg1 106 0.76 104.68 1.41 88.52
199 INT189946 Positive_regulation of Gene_expression of Pttg1 14 0.68 23.72 0.38 88.52
200 INT45041 Gene_expression of IGLL1 18 0.66 15.45 1.59 88.48
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