D:Esophageal Varices

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pChart

Disease Term
Synonyms ESOPHAGEAL GASTRIC VARICES, Esophageal Varix, ESOPHAGUS VARIX, Ev Oesophageal Varices, GASTRIC VARICES, Gastric Varix, Oesophageal Varices, OESOPHAGUS VARIX, Ov Esophageal Varices, VARICES ESOPHAGEAL, Varices Gastric
Documents 320
Hot Single Events 36
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Esophageal Varices. They are ordered first by their relevance to Esophageal Varices and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT227400 Binding of DLAT and HCC 1 0.01 2.82 0.11 89.00
2 INT190683 Binding of A2M and INS 4 0.11 4.97 0.32 5.00
3 INT191240 SAE1 Regulation of Localization of INS 1 0.08 1.15 0.3 5.00
4 INT191241 SST Regulation of SAE1 1 0.05 0.89 0.18 5.00
5 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
6 INT190684 Binding of A2M and IGF1 1 0.16 1.54 0.1 5.00
7 INT171709 Rac1 Negative_regulation of Localization of Chrna7 1 0.04 0.75 0.08 5.00
8 INT227418 Binding of DLAT and Pdc 1 0.05 1.01 0.07 5.00
9 INT296893 Nps Negative_regulation of Gene_expression of REN 1 0.00 1.05 0.04 5.00
10 INT212584 IFNA1 Regulation of Gene_expression of CD4 1 0.21 0.98 0.03 5.00
11 INT186502 Binding of AMELX and HLA-A 1 0.00 0.71 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Esophageal Varices. They are ordered first by their pain relevance and then by number of times they were reported in Esophageal Varices. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT277080 Phosphorylation of Ectopic 1 0.09 1.74 0.14 99.76
2 INT63505 Negative_regulation of F2 18 0.57 7.4 2.2 99.60
3 INT79140 Binding of HCC 36 0.31 46.96 1.87 98.92
4 INT4047 Binding of F13A1 105 0.43 66.54 11.81 98.80
5 INT354483 Gene_expression of Evl 1 0.49 1.92 0.1 98.16
6 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 96.88
7 INT90416 Positive_regulation of RASA1 3 0.67 1.58 0.56 96.36
8 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 95.08
9 INT10094 Negative_regulation of ALPP 36 0.37 20.45 6.45 95.08
10 INT24029 Regulation of AFP 7 0.44 6.45 0.51 94.64
11 INT14916 Binding of RASA1 15 0.37 13.64 1.44 93.88
12 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 93.60
13 INT3913 Positive_regulation of ABAT 47 0.69 22.73 33.4 92.96
14 INT17565 Regulation of Gpt 85 0.60 43.64 13.68 91.72
15 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 91.64
16 INT37335 Gene_expression of Nsdhl 45 0.51 24.36 4.58 90.32
17 INT21299 Negative_regulation of Hp 14 0.44 10.97 2.97 90.08
18 INT34809 Gene_expression of Ec 36 0.15 15.7 3.24 89.92
19 INT152353 Binding of Evl 3 0.42 2.01 0.33 89.92
20 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 89.56
21 INT148 Positive_regulation of Gnrhr 182 0.70 47.44 79.64 89.00
22 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82 87.48
23 INT477 Localization of Avp 813 0.81 131.58 300.4 87.28
24 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 87.04
25 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 85.60
26 INT8670 Negative_regulation of Afp 27 0.58 19.85 2.87 85.52
27 INT139108 Gene_expression of Hgd 3 0.38 4.69 0.6 84.84
28 INT180029 Regulation of rsm1 3 0.02 2.38 0.55 82.96
29 INT1038 Negative_regulation of F2 26 0.58 15.12 6.75 81.92
30 INT39444 Negative_regulation of Positive_regulation of F2 7 0.59 5.82 1.42 81.92
31 INT187286 Binding of HEY1 17 0.32 31.21 4.52 81.76
32 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15 81.44
33 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64 81.36
34 INT209783 Binding of SLC15A4 2 0.04 1.25 0.3 81.20
35 INT345973 Binding of EVL 1 0.07 1.4 0.14 80.88
36 INT8743 Positive_regulation of Gcg 19 0.65 10.63 4.43 80.80
37 INT1153 Negative_regulation of FUT3 17 0.38 8.61 2.21 78.24
38 INT64224 Localization of FUT3 3 0.06 3.16 0.2 78.24
39 INT8669 Positive_regulation of Afp 66 0.70 58.21 7.67 78.00
40 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 77.80
41 INT5499 Transcription of Avp 52 0.72 7.98 19.87 76.80
42 INT70242 Localization of HCC 18 0.66 23.95 2.35 76.44
43 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23 75.12
44 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 75.00
45 INT846 Positive_regulation of B2M 42 0.70 29.78 8.06 75.00
46 INT60498 Negative_regulation of Positive_regulation of B2M 1 0.09 0.54 0.1 75.00
47 INT354484 Negative_regulation of Evl 1 0.31 3.86 0 74.16
48 INT354486 Negative_regulation of Positive_regulation of Evl 1 0.31 1.95 0 74.16
49 INT354485 Positive_regulation of Evl 1 0.36 1.72 0 74.16
50 INT103260 Positive_regulation of Nps 35 0.48 23.8 5.67 74.08
51 INT237866 Positive_regulation of Positive_regulation of Nps 5 0.48 2.67 0.69 74.08
52 INT175260 Negative_regulation of Gene_expression of SH2B2 2 0.25 4.41 0.21 72.80
53 INT21962 Localization of KLK1 15 0.78 3.54 1.61 70.48
54 INT96542 Negative_regulation of SMN1 14 0.51 10.72 3.11 68.68
55 INT102187 Gene_expression of SH2B2 23 0.59 26.54 4.39 67.92
56 INT18011 Positive_regulation of HP 60 0.50 31.88 4.75 67.80
57 INT11493 Positive_regulation of KLK1 21 0.67 9.22 5 66.24
58 INT96447 Regulation of SMN1 4 0.17 2.59 0.57 64.56
59 INT7351 Gene_expression of NPS 5 0.58 1.87 0.88 64.12
60 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 64.00
61 INT2132 Localization of SCT 29 0.81 8.39 5.43 63.84
62 INT159127 Gene_expression of Nps 49 0.75 16.91 12.06 63.52
63 INT237862 Positive_regulation of Gene_expression of Nps 8 0.43 3.82 1.52 63.52
64 INT72558 Regulation of CYP2C19 6 0.54 1.97 1.14 63.20
65 INT250645 Gene_expression of Samsn1 6 0.33 9.95 0.86 61.60
66 INT11650 Negative_regulation of Gpt 122 0.59 69.15 30.36 58.00
67 INT894 Binding of Avp 84 0.48 29.16 29.63 57.64
68 INT44540 Binding of GPT 3 0.36 6.14 0.23 54.80
69 INT249 Localization of GHRH 215 0.80 78.02 51.87 54.64
70 INT986 Negative_regulation of Localization of GHRH 16 0.58 8.57 3.16 54.64
71 INT50444 Negative_regulation of Gene_expression of Alb 11 0.39 7.63 1.06 54.24
72 INT196321 Negative_regulation of Gene_expression of F2 2 0.17 1.48 0.04 54.24
73 INT21712 Positive_regulation of APOA1 32 0.67 21.64 2.64 53.44
74 INT39516 Gene_expression of Alb 81 0.75 30.08 6.59 53.36
75 INT22839 Gene_expression of F2 31 0.74 15.53 5.56 53.04
76 INT236277 Positive_regulation of Gene_expression of CADPS 5 0.42 9.17 1.29 52.44
77 INT209501 Gene_expression of CADPS 15 0.65 20.7 2.22 52.44
78 INT259031 Negative_regulation of Gene_expression of CADPS 1 0.07 3.04 0.35 52.44
79 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 52.40
80 INT101693 Gene_expression of Ggt1 2 0.65 4.92 0.81 52.40
81 INT2740 Negative_regulation of Localization of SCT 3 0.42 0.42 0.44 52.08
82 INT546 Binding of ALB 311 0.48 85.98 60.14 51.52
83 INT101105 Positive_regulation of FUT1 62 0.30 55.96 9.28 51.36
84 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 50.04
85 INT79425 Gene_expression of SMN1 42 0.65 36.37 6.1 50.04
86 INT28308 Localization of SLC17A5 10 0.73 6.77 0.7 49.20
87 INT2243 Localization of GAST 67 0.81 34.54 16.19 48.56
88 INT2242 Negative_regulation of Localization of GAST 12 0.58 5.55 4.22 48.56
89 INT397 Localization of SST 232 0.81 58.05 101.19 48.00
90 INT34808 Binding of Ec 14 0.24 17.27 2.65 46.40
91 INT27555 Positive_regulation of Ec 12 0.14 7.38 2.3 44.64
92 INT17274 Gene_expression of Got1 11 0.58 3.98 2 44.08
93 INT81965 Gene_expression of F5 16 0.65 13.29 0.48 41.80
94 INT64709 Gene_expression of VTN 11 0.67 11.01 1.97 41.16
95 INT227414 Localization of DLAT 2 0.49 5.14 0.26 39.40
96 INT175262 Binding of SH2B2 18 0.36 22.85 3.18 39.04
97 INT75105 Gene_expression of SLC15A4 3 0.19 3.33 0.74 38.20
98 INT117031 Binding of Samsn1 6 0.21 6.82 0.76 37.96
99 INT176618 Gene_expression of HEY1 29 0.59 36 4.37 37.92
100 INT35584 Binding of ACLY 22 0.35 31.78 7.17 34.16
101 INT154057 Gene_expression of Ear1 14 0.41 9.72 1.12 32.12
102 INT17934 Localization of MLN 16 0.80 2.83 2.24 26.80
103 INT39919 Negative_regulation of MLN 9 0.36 2.91 1.06 26.80
104 INT4820 Negative_regulation of SCT 7 0.43 4.06 3.01 26.08
105 INT628 Negative_regulation of GAST 10 0.58 4.44 2.08 25.28
106 INT625 Localization of PGC 35 0.80 11.33 3.05 24.56
107 INT629 Negative_regulation of Localization of PGC 8 0.45 5.79 1.33 24.56
108 INT32704 Negative_regulation of PGC 11 0.54 5.75 1.23 24.56
109 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81 20.92
110 INT209503 Positive_regulation of CADPS 3 0.42 7 1.11 18.12
111 INT812 Localization of INS 1026 0.81 515.6 145.31 16.56
112 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 16.56
113 INT17625 Localization of GCG 210 0.80 55.69 24.97 16.56
114 INT26492 Negative_regulation of Localization of GCG 73 0.58 22.2 9.48 16.56
115 INT84264 Regulation of NPPB 22 0.61 21.18 1.94 8.12
116 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 7.28
117 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 7.28
118 INT152681 Gene_expression of PDPN 29 0.65 23.06 0.18 7.28
119 INT1308 Localization of Pomc 457 0.81 66.83 217.5 5.00
120 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
121 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
122 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 5.00
123 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
124 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
125 INT214 Localization of AVP 370 0.81 208.51 91.09 5.00
126 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
127 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 5.00
128 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 5.00
129 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 5.00
130 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
131 INT654 Localization of REN 250 0.81 75.12 47.86 5.00
132 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41 5.00
133 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 5.00
134 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
135 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
136 INT2364 Localization of Sct 134 0.80 26.21 41.47 5.00
137 INT685 Regulation of AVP 124 0.62 34.9 39.91 5.00
138 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
139 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
140 INT23330 Binding of Chrna7 79 0.48 10.06 35.5 5.00
141 INT5743 Localization of NA 104 0.59 14.35 35.29 5.00
142 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 5.00
143 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 5.00
144 INT691 Binding of SST 67 0.48 24.66 32.67 5.00
145 INT20307 Positive_regulation of Cyp2e1 70 0.70 23.59 32.49 5.00
146 INT19396 Regulation of Rac1 66 0.53 37.41 30.01 5.00
147 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
148 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
149 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27 5.00
150 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33 5.00
151 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 5.00
152 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91 5.00
153 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 5.00
154 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
155 INT6127 Regulation of Localization of AVP 60 0.62 15.12 20.84 5.00
156 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 5.00
157 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 5.00
158 INT20305 Gene_expression of Cyp2e1 53 0.78 19.75 19.54 5.00
159 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 5.00
160 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 5.00
161 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 5.00
162 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04 5.00
163 INT213 Negative_regulation of Localization of AVP 46 0.59 19.78 16.79 5.00
164 INT653 Negative_regulation of Localization of REN 67 0.59 20.33 16.7 5.00
165 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64 5.00
166 INT10721 Gene_expression of BDNF-AS 119 0.76 72.8 16.29 5.00
167 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1 5.00
168 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 5.00
169 INT9191 Localization of EDN1 94 0.81 57.01 14.78 5.00
170 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 5.00
171 INT655 Positive_regulation of Localization of REN 86 0.70 32.41 13.56 5.00
172 INT14572 Binding of INS 205 0.48 175.43 13.38 5.00
173 INT13823 Gene_expression of Egf 97 0.78 39.99 12.99 5.00
174 INT3040 Gene_expression of MIA3 81 0.24 53.61 12.62 5.00
175 INT28458 Localization of Slc6a3 31 0.76 2.33 12.49 5.00
176 INT178338 Gene_expression of Tbx15 50 0.65 38.65 12.19 5.00
177 INT36287 Binding of CD4 96 0.47 58.93 11.88 5.00
178 INT661 Gene_expression of REN 100 0.78 48.21 11.36 5.00
179 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 5.00
180 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 5.00
181 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47 5.00
182 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9 5.00
183 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51 5.00
184 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37 5.00
185 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28 5.00
186 INT33220 Negative_regulation of ras 110 0.58 70.21 9.19 5.00
187 INT107087 Positive_regulation of Gene_expression of Cyp2e1 20 0.70 8.89 9.04 5.00
188 INT20371 Gene_expression of Cd8a 125 0.60 67.59 8.97 5.00
189 INT44550 Positive_regulation of Gene_expression of AVP 38 0.70 22.27 8.62 5.00
190 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36 5.00
191 INT15529 Gene_expression of GCG 51 0.75 18.55 8.35 5.00
192 INT72337 Positive_regulation of Positive_regulation of Nos2 37 0.65 17.02 8.11 5.00
193 INT165036 Gene_expression of S100a9 38 0.77 38.33 7.84 5.00
194 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 5.00
195 INT8684 Positive_regulation of ANGPTL5 45 0.69 36.29 7.47 5.00
196 INT17049 Localization of CD4 57 0.75 35.33 6.89 5.00
197 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 5.00
198 INT84685 Regulation of BCL2 67 0.60 72.96 6.65 5.00
199 INT25022 Binding of PAEP 66 0.42 22.83 6.59 5.00
200 INT62950 Gene_expression of NPPB 73 0.75 65.91 6.54 5.00
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