D:Eye Disease

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Disease Term
Synonyms Disease Eye, Diseases Eye, Diseases Syndromes Of Eye, Eye Disease Syndrome, EYE DISEASES, Eye Disorder, Eye Disorders, GENERAL EYE DISEASES SYNDROMES, Ocular Disease, Ocular Diseases, Oculopathy
Documents 576
Hot Single Events 200
Hot Interactions 10

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Eye Disease. They are ordered first by their relevance to Eye Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT233397 Binding of ABCA4 and COL2A1 1 0.38 3.59 0.03 100.00
2 INT311590 EGF Regulation of Gene_expression of CXCL10 1 0.23 0.51 0.43 100.00
3 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43 100.00
4 INT311591 CXCL10 Regulation of Gene_expression of EGF 1 0.23 0.51 0.43 100.00
5 INT311587 CXCL10 Regulation of Gene_expression of VEGFA 1 0.23 0.45 0.43 100.00
6 INT177958 IGHE Positive_regulation of TNF 1 0.03 2.23 0 98.32
7 INT177959 Positive_regulation of IGHE Positive_regulation of TNF 1 0.03 2.23 0 98.32
8 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87 94.20
9 INT274095 Binding of EDNRA and OPA1 1 0.12 0.65 0.04 90.56
10 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02 85.44
11 INT272143 PTAFR Positive_regulation of Gene_expression of PTGS2 1 0.12 1.59 0.23 75.60
12 INT239327 Positive_regulation of Binding of Lcat and Hdl1 1 0.06 1.52 0.06 75.52
13 INT239326 Binding of Lcat and Hdl1 1 0.05 1.52 0.06 75.52
14 INT249332 GPNMB Positive_regulation of EGFR 1 0.17 2.63 0.08 72.08
15 INT249324 GPNMB Positive_regulation of GPNMB Positive_regulation of EGFR 1 0.12 1.31 0.04 71.60
16 INT271025 Binding of Car2 and Casq1 1 0.03 0.7 0.03 71.12
17 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2 70.92
18 INT259936 CTLA4 Regulation of PTPN22 1 0.45 1.64 0.28 69.44
19 INT328626 Binding of TBCE and MUC16 1 0.15 0.79 0 68.92
20 INT288025 VEGFA Regulation of IL6 1 0.36 0.26 0.03 65.68
21 INT288027 VEGFA Regulation of CCL2 1 0.44 0.26 0.03 65.68
22 INT288028 VEGFA Regulation of IL8 1 0.36 0.26 0.03 65.68
23 INT282864 Bpifa2 Positive_regulation of Gene_expression of Serpinf1 1 0.15 1.16 0.2 65.52
24 INT282866 Bpifa2 Negative_regulation of Gene_expression of VEGFA 1 0.11 1.14 0.19 65.52
25 INT244130 Binding of CASP1 and RNGTT 1 0.07 0.24 0.07 64.08
26 INT244131 Binding of RNGTT and NLRP1 1 0.11 0.24 0.07 64.08
27 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34 63.44
28 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61 62.64
29 INT282863 Bpifa2 Positive_regulation of Gene_expression of Aggf1 1 0.01 1.07 0.19 61.16
30 INT245835 Plg Negative_regulation of Gene_expression of VEGFA 1 0.05 3.51 0 61.04
31 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 59.92
32 INT328627 Binding of LGALS3 and MUC16 1 0.04 0.73 0 59.20
33 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26 58.28
34 INT239355 Binding of Nr1h2 and Positive_regulation of Gene_expression of CETP 1 0.17 3.75 0.14 55.00
35 INT239323 Binding of Nr1h2 and Positive_regulation of Positive_regulation of Tgfb1 1 0.00 3.71 0.14 54.12
36 INT243119 Binding of amd and Sod2 1 0.29 3.25 0.06 52.84
37 INT304964 Binding of AMT and PTK2B 1 0.23 0.78 0.18 50.64
38 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 50.12
39 INT227556 Ptgds Positive_regulation of Ppara 1 0.18 0.62 0.13 50.00
40 INT173051 Binding of VEGFA and NRP1 16 0.44 1.29 0.04 47.28
41 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9 41.24
42 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97 34.00
43 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62 34.00
44 INT274096 Binding of EDN1 and EDNRA Positive_regulation of Positive_regulation of EDN1 1 0.22 0.78 0 34.00
45 INT298703 Angpt1 Regulation of Tek 1 0.12 0.27 0.03 32.72
46 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22 31.76
47 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22 31.76
48 INT289997 CNTF Negative_regulation of Binding of CNTF and Casp3 1 0.05 0.99 0.22 31.76
49 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22 31.76
50 INT282859 Bpifa2 Negative_regulation of Mapk1 1 0.01 0.91 0.17 31.60
51 INT282858 Bpifa2 Negative_regulation of Akt1 1 0.05 0.91 0.17 30.72
52 INT282861 Bpifa2 Negative_regulation of Phosphorylation of Akt1 1 0.05 0.91 0.17 30.72
53 INT300512 Binding of Plau and Vtn 1 0.06 2.28 0.13 30.16
54 INT300511 Binding of Plaur and Vtn 1 0.10 2.28 0.13 30.16
55 INT300513 Binding of Serpine1 and Vtn 1 0.17 2.27 0.13 30.16
56 INT289463 IRF6 Positive_regulation of Localization of IL1B 1 0.05 0.52 0.48 29.28
57 INT243120 Binding of amd and Rpe 1 0.26 1.18 0 28.16
58 INT342229 SEPP1 Regulation of ARC 1 0.03 0.44 0 25.60
59 INT342228 PKD1P4 Regulation of ARC 1 0.00 0.44 0 25.60
60 INT219229 Binding of Col7a1 and Ighv10-3 1 0.00 0.46 0 25.00
61 INT298637 ZDHHC2 Negative_regulation of Gene_expression of VEGFA 1 0.01 0.27 0.04 22.00
62 INT243118 amd Regulation of Rpe 1 0.20 1.16 0 14.64
63 INT229983 Binding of CFH and Crp 2 0.14 1.48 0 13.88
64 INT219230 Binding of Ecm1 and Ighv10-3 1 0.00 0.26 0.04 9.72
65 INT245831 Phosphorylation of Mapk3 Positive_regulation of Gene_expression of VEGFA 1 0.05 0.58 0 9.08
66 INT227943 Binding of Vip and Mlph 1 0.01 0.33 0.36 6.24
67 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16 5.00
68 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
69 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99 5.00
70 INT203040 Binding of PDCD1 and PDCD1LG2 3 0.40 4.86 0.98 5.00
71 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93 5.00
72 INT289461 IRF6 Positive_regulation of ICAM1 1 0.08 0.61 0.91 5.00
73 INT272144 PTAFR Positive_regulation of HRASLS 1 0.08 1.08 0.89 5.00
74 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73 5.00
75 INT272147 PTAFR Positive_regulation of CA2 1 0.13 0 0.71 5.00
76 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 5.00
77 INT203046 Binding of PDCD1 and CD274 2 0.40 3.97 0.68 5.00
78 INT231533 IL4 Positive_regulation of LRP5 1 0.00 0.87 0.67 5.00
79 INT231534 Binding of JAK1 and SOAT1 1 0.01 0.6 0.64 5.00
80 INT275562 Il1 Regulation of Gene_expression of Cxcl2 1 0.02 1.41 0.64 5.00
81 INT272146 PTAFR Positive_regulation of Localization of IL8 3 0.38 0.28 0.59 5.00
82 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56 5.00
83 INT172081 TNF Regulation of IFNA1 1 0.03 1.13 0.5 5.00
84 INT172082 TNF Regulation of SFTPA1 1 0.05 0.85 0.5 5.00
85 INT289464 Negative_regulation of IRF6 Positive_regulation of ICAM1 1 0.07 0.31 0.5 5.00
86 INT289462 Negative_regulation of IRF6 Positive_regulation of IL1B 2 0.04 0.31 0.48 5.00
87 INT344709 Niacr1 Positive_regulation of Hdl1 1 0.32 2.74 0.46 5.00
88 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43 5.00
89 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43 5.00
90 INT272148 PTAFR Regulation of Localization of CA2 1 0.14 0 0.38 5.00
91 INT169604 Nppb Positive_regulation of Npr1 2 0.52 2.52 0.37 5.00
92 INT204943 Il6 Regulation of Slc39a14 1 0.00 0.54 0.36 5.00
93 INT231535 Binding of JAK2 and SOAT1 1 0.01 0.3 0.35 5.00
94 INT239344 Nr1h2 Positive_regulation of Gene_expression of Srebf1 1 0.26 0.84 0.29 5.00
95 INT239324 Nr1h2 Positive_regulation of Hltf 1 0.04 0.78 0.29 5.00
96 INT239347 Nr1h2 Positive_regulation of Srebf1 1 0.26 0.78 0.29 5.00
97 INT239329 Nr1h2 Positive_regulation of Gene_expression of Hltf 1 0.04 0.84 0.29 5.00
98 INT239336 Nr1h2 Positive_regulation of Gene_expression of Fas 1 0.07 0.84 0.29 5.00
99 INT344704 Positive_regulation of Ppara Positive_regulation of Binding of Hdl1 1 0.13 0.83 0.28 5.00
100 INT344715 Positive_regulation of Ppara Positive_regulation of Gene_expression of Pltp 1 0.02 0.83 0.28 5.00
101 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 5.00
102 INT177961 Binding of CCR3 and CCL11 1 0.04 0.73 0.26 5.00
103 INT239335 Eef1a2 Positive_regulation of Ppara 1 0.27 0.57 0.26 5.00
104 INT259937 Binding of CSK and PTPN22 1 0.21 1.69 0.25 5.00
105 INT177957 CCL11 Regulation of Binding of IL5 and CCL11 1 0.01 0.71 0.25 5.00
106 INT177960 Binding of IL5 and CCL11 1 0.03 0.71 0.25 5.00
107 INT261976 Binding of PDCD1 and SUGT1 1 0.00 1.3 0.25 5.00
108 INT316815 Ctgf Negative_regulation of Gene_expression of Sparc 1 0.47 0.64 0.24 5.00
109 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24 5.00
110 INT344714 Nr1h4 Negative_regulation of Gene_expression of Lipg 1 0.02 0.77 0.23 5.00
111 INT230748 Agtr2 Positive_regulation of Gene_expression of Ros1 2 0.05 1.04 0.23 5.00
112 INT172083 TNF Regulation of Regulation of IFNA1 1 0.03 0.91 0.22 5.00
113 INT316810 Sparc Regulation of Col1a1 1 0.13 0.48 0.21 5.00
114 INT272150 Positive_regulation of PTAFR Positive_regulation of HRASLS 1 0.06 0.16 0.21 5.00
115 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21 5.00
116 INT177962 IL4 Positive_regulation of VCAM1 1 0.02 0.97 0.2 5.00
117 INT239328 Hdl1 Regulation of Gene_expression of Kitl 1 0.08 1.86 0.2 5.00
118 INT304882 Agtr2 Positive_regulation of Mapk1 1 0.07 0.95 0.2 5.00
119 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 5.00
120 INT340816 Tnfrsf14 Regulation of Gene_expression of Btla 1 0.11 1.09 0.18 5.00
121 INT345924 IL6 Regulation of Gene_expression of SPHAR 1 0.00 0.21 0.18 5.00
122 INT239316 Nr1h2 Positive_regulation of Transcription of Abca1 1 0.15 0.67 0.18 5.00
123 INT268279 Positive_regulation of Binding of Aggf1 and Alms1 1 0.02 0.15 0.18 5.00
124 INT268280 Binding of Aggf1 and Alms1 1 0.01 0.15 0.18 5.00
125 INT329670 Csf2 Regulation of Col7a1 1 0.03 0.4 0.17 5.00
126 INT229928 Binding of C3 and CFH 1 0.07 1.35 0.17 5.00
127 INT229931 Negative_regulation of Binding of C3 and CFH 1 0.08 1.35 0.17 5.00
128 INT298641 PPARA Regulation of STAT3 1 0.23 0.98 0.16 5.00
129 INT251349 Ifnar1 Positive_regulation of Rock1 1 0.01 1.27 0.16 5.00
130 INT251347 Binding of Bmpr2 and Limk1 1 0.18 1.51 0.16 5.00
131 INT340822 Trav6-3 Regulation of Gene_expression of Btla 1 0.07 0.97 0.15 5.00
132 INT288026 PROC Positive_regulation of Gene_expression of VEGFA 1 0.01 0.5 0.15 5.00
133 INT344721 Binding of AHA and Hdl1 1 0.02 1.16 0.15 5.00
134 INT314856 Binding of Cdc7 and Cdkn2a 1 0.28 1.34 0.14 5.00
135 INT213005 Hdl1 Positive_regulation of Akt1 3 0.19 3.81 0.14 5.00
136 INT302676 Binding of OPA1 and MFN2 1 0.46 1.12 0.14 5.00
137 INT344707 Scarb1 Positive_regulation of Positive_regulation of Hdl1 1 0.14 0.88 0.14 5.00
138 INT344710 Lipc Positive_regulation of Positive_regulation of Hdl1 1 0.04 0.87 0.14 5.00
139 INT239317 Egfl7 Positive_regulation of Hdl1 2 0.01 2.3 0.14 5.00
140 INT298639 GDE1 Negative_regulation of AKT1 1 0.00 1.14 0.14 5.00
141 INT314867 Binding of Cdc7 and Cdkn2b 1 0.25 1.16 0.14 5.00
142 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14 5.00
143 INT314859 Binding of Cdkn2b and Tgfbr3 1 0.33 1.16 0.14 5.00
144 INT282862 Bpifa2 Negative_regulation of Positive_regulation of Akt1 1 0.05 0.75 0.13 5.00
145 INT316817 Ifnar1 Positive_regulation of Phosphorylation of Insrr 1 0.00 0.43 0.13 5.00
146 INT272145 Binding of PTAFR and HRASLS 1 0.04 0.06 0.13 5.00
147 INT239339 Hdl1 Negative_regulation of Gene_expression of Paf 1 0.02 1.43 0.13 5.00
148 INT344705 Nr1h2 Regulation of Scarb1 1 0.04 1.53 0.12 5.00
149 INT261690 Binding of GSC and TCF23 1 0.10 0 0.12 5.00
150 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12 5.00
151 INT340819 Regulation of Binding of Ly6g6d and Tnfrsf14 1 0.01 1.58 0.12 5.00
152 INT272149 PTAFR Positive_regulation of Localization of IL6 1 0.24 0 0.12 5.00
153 INT344713 Nr1h2 Regulation of Abcg1 1 0.03 2.39 0.12 5.00
154 INT340818 Binding of Ly6g6d and Tnfrsf14 1 0.01 1.57 0.12 5.00
155 INT321965 Rock1 Positive_regulation of Nos3 1 0.28 1.99 0.12 5.00
156 INT316813 Sparc Negative_regulation of Gene_expression of Col1a1 1 0.13 0.67 0.12 5.00
157 INT251348 Ifnar1 Positive_regulation of Limk2 1 0.01 1.12 0.11 5.00
158 INT287381 Cxcl2 Regulation of Gene_expression of VEGFA 1 0.42 1.1 0.1 5.00
159 INT316823 Sparc Positive_regulation of Phosphorylation of Smad2 1 0.44 0.49 0.1 5.00
160 INT304881 Ros1 Positive_regulation of Mapk1 1 0.25 0.36 0.1 5.00
161 INT316818 Sparc Regulation of Gene_expression of Col7a1 1 0.06 0.74 0.09 5.00
162 INT304887 Agtr2 Positive_regulation of Positive_regulation of Mapk1 1 0.10 0.45 0.09 5.00
163 INT304886 Agtr2 Positive_regulation of Ros1 1 0.03 0.45 0.09 5.00
164 INT316824 Negative_regulation of Sparc Negative_regulation of Gene_expression of Col7a1 1 0.10 0.82 0.09 5.00
165 INT304883 Agtr2 Positive_regulation of Agtrap 1 0.10 0.46 0.09 5.00
166 INT342232 Binding of POR and SEPP1 1 0.02 0.75 0.08 5.00
167 INT298634 Binding of IL6 and STAT3 1 0.04 1.41 0.08 5.00
168 INT304884 Agtrap Positive_regulation of Gene_expression of Ros1 1 0.17 0.48 0.08 5.00
169 INT262939 PAX6 Regulation of CDH4 1 0.02 0.97 0.08 5.00
170 INT259938 Binding of CTLA4 and PTPN22 1 0.36 0.85 0.08 5.00
171 INT342231 Binding of SEPP1 and ARC 1 0.04 3.84 0.08 5.00
172 INT262937 PAX6 Regulation of CDH8 1 0.03 0.98 0.08 5.00
173 INT262944 PAX6 Regulation of CDH6 1 0.03 0.97 0.08 5.00
174 INT336341 Binding of RTCA and ELOVL1 1 0.02 2.15 0.07 5.00
175 INT236531 Binding of Cacna1f and Flna 1 0.08 0 0.07 5.00
176 INT239346 Olfr642 Positive_regulation of Lcat 1 0.00 1.06 0.07 5.00
177 INT342230 Binding of ARC and PKD1P4 1 0.01 5.72 0.07 5.00
178 INT311432 Binding of TSHR and TAOK1 1 0.12 1.05 0.07 5.00
179 INT345925 IL6 Negative_regulation of Gene_expression of CYP1A2 1 0.13 0.18 0.06 5.00
180 INT316819 Sparc Negative_regulation of Gene_expression of Ctgf 1 0.41 0.24 0.06 5.00
181 INT316822 Sparc Regulation of Gene_expression of Ctgf 1 0.68 0.48 0.06 5.00
182 INT298699 Kdr Regulation of Tek 1 0.11 0.28 0.06 5.00
183 INT229977 Binding of amd and Cfb 1 0.03 2.78 0.06 5.00
184 INT298701 Manea Regulation of Tek 1 0.03 0.28 0.06 5.00
185 INT239331 RCT Positive_regulation of Lcat 1 0.08 1.08 0.06 5.00
186 INT304885 Gene_expression of Ros1 Positive_regulation of Positive_regulation of Mapk1 1 0.14 0.52 0.06 5.00
187 INT239354 CETP Positive_regulation of Lcat 1 0.28 1.09 0.06 5.00
188 INT229982 Binding of C3 and amd 1 0.02 1.14 0.06 5.00
189 INT229985 Binding of C2 and amd 1 0.01 1.89 0.06 5.00
190 INT298638 IL6 Positive_regulation of IL6R 1 0.00 0.9 0.05 5.00
191 INT353105 Binding of Aes and Rgs9bp 1 0.01 0.35 0.05 5.00
192 INT344719 Hdl1 Positive_regulation of Plat 1 0.10 1.23 0.05 5.00
193 INT239318 Binding of Cor and Hdl1 1 0.07 1.69 0.05 5.00
194 INT308328 Hif1a Regulation of Positive_regulation of Trib3 1 0.02 0.89 0.05 5.00
195 INT239348 Binding of Apoa1 and Hdl1 1 0.03 3.34 0.05 5.00
196 INT344703 Hdl1 Negative_regulation of Gene_expression of Serpine1 1 0.07 1.26 0.05 5.00
197 INT282860 Bpifa2 Regulation of Mapk1 1 0.01 0.65 0.05 5.00
198 INT239334 Ppara Negative_regulation of Gene_expression of Apo 1 0.06 1.18 0.05 5.00
199 INT273068 Binding of P2RY2 and TFAP4 1 0.01 0.27 0.05 5.00
200 INT298635 PPARA Negative_regulation of Localization of ZDHHC2 1 0.01 0.21 0.05 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Eye Disease. They are ordered first by their pain relevance and then by number of times they were reported in Eye Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 100.00
2 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 100.00
3 INT311605 Positive_regulation of AATF 5 0.06 6.72 1.05 100.00
4 INT233399 Binding of ABCA4 9 0.46 9.49 0.07 100.00
5 INT96693 Binding of COL2A1 45 0.46 37.11 2.61 100.00
6 INT227557 Binding of FAM155B 1 0.08 3.66 0.45 100.00
7 INT311604 Gene_expression of AATF 3 0.06 2.9 0.55 100.00
8 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 100.00
9 INT24042 Gene_expression of MUC5AC 98 0.77 74.99 6.18 100.00
10 INT311601 Binding of AATF 1 0.03 0.99 0.15 100.00
11 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 100.00
12 INT227558 Gene_expression of FAM155B 1 0.12 1.82 0.06 100.00
13 INT311603 Transcription of AATF 1 0.06 1 0.2 100.00
14 INT173022 Regulation of Gene_expression of MUC1 9 0.60 7.59 0.44 100.00
15 INT92234 Regulation of CXCL10 15 0.42 8.37 5.09 100.00
16 INT328632 Regulation of Gene_expression of MUC5AC 1 0.25 2.46 0 100.00
17 INT52625 Regulation of IL1RN 30 0.61 19.12 11.31 100.00
18 INT37227 Regulation of EGF 19 0.45 11.16 5.17 100.00
19 INT311594 Regulation of Cx3cl1 1 0.19 0.3 0.43 100.00
20 INT311444 Binding of TAOK1 1 0.11 0.65 0.05 100.00
21 INT340801 Negative_regulation of Binding of Btla 1 0.37 2.7 0.27 99.96
22 INT123563 Negative_regulation of Rock1 7 0.55 16.56 5.78 99.96
23 INT49803 Negative_regulation of MUC1 37 0.58 26.37 2.06 99.88
24 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.84
25 INT6480 Positive_regulation of IL1RN 59 0.69 33.7 16.66 99.84
26 INT64609 Negative_regulation of PLXNA3 5 0.57 3.64 1.94 99.84
27 INT93350 Binding of Lepr 17 0.05 27.21 1.5 99.82
28 INT205189 Gene_expression of TBCE 12 0.25 9.67 1.19 99.80
29 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7 99.80
30 INT205188 Positive_regulation of Gene_expression of TBCE 5 0.19 2.14 0.74 99.80
31 INT142607 Positive_regulation of Gene_expression of Cd40 41 0.62 13.85 5.51 99.80
32 INT257449 Regulation of Gene_expression of TBCE 1 0.09 0.85 0 99.80
33 INT235781 Positive_regulation of PAX6 2 0.50 0.36 0.08 99.78
34 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 99.76
35 INT138920 Regulation of Gene_expression of Cxcl10 5 0.59 5.72 2.1 99.72
36 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.56
37 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 99.56
38 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 99.56
39 INT340812 Binding of Btla 1 0.32 5.94 0.39 99.56
40 INT101594 Positive_regulation of Cd40 36 0.69 16.14 4.56 99.54
41 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 99.48
42 INT176607 Gene_expression of Cx3cl1 27 0.75 19.51 11.32 99.48
43 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47 99.48
44 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 99.48
45 INT92237 Positive_regulation of Gene_expression of CXCL10 43 0.70 43.67 13.65 99.44
46 INT94335 Positive_regulation of CXCL10 71 0.58 50.69 23 99.44
47 INT104392 Gene_expression of Cxcl10 113 0.75 106.86 34.12 99.44
48 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 99.42
49 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 99.42
50 INT311592 Positive_regulation of Cx3cl1 2 0.67 1.93 1.01 99.42
51 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68 99.42
52 INT8096 Positive_regulation of Gene_expression of EGF 21 0.69 13.43 3.47 99.42
53 INT173003 Negative_regulation of Gene_expression of MUC1 15 0.57 10.27 0.79 99.40
54 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 99.36
55 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 99.30
56 INT117785 Regulation of Gene_expression of EGF 7 0.44 4.22 2.87 99.24
57 INT208142 Gene_expression of PITX1 3 0.65 9.36 0.73 99.20
58 INT8547 Gene_expression of MUC16 116 0.78 75.97 12.18 99.16
59 INT49804 Negative_regulation of Localization of MUC1 7 0.59 5.84 1.19 99.16
60 INT11889 Regulation of Gene_expression of MUC16 5 0.62 3.24 0.63 99.16
61 INT49802 Localization of MUC1 75 0.81 44.74 8.87 99.00
62 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 98.96
63 INT137609 Localization of Vegfa 22 0.78 14.67 3.01 98.96
64 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 98.92
65 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 98.92
66 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 98.92
67 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 98.92
68 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01 98.80
69 INT49805 Positive_regulation of MUC1 56 0.70 44.5 4.56 98.76
70 INT8546 Positive_regulation of MUC16 99 0.69 74.98 11.26 98.76
71 INT11033 Positive_regulation of Gene_expression of MUC16 21 0.69 15.75 1.89 98.76
72 INT61626 Transcription of IL6 73 0.72 42.04 17.86 98.72
73 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 98.72
74 INT5806 Regulation of Edn1 63 0.62 23.46 13.88 98.68
75 INT140071 Negative_regulation of Positive_regulation of Cd4 5 0.39 3.9 0.42 98.68
76 INT239274 Negative_regulation of Gene_expression of Lcat 1 0.43 1.6 0 98.68
77 INT219108 Negative_regulation of Gene_expression of MUC5AC 11 0.31 9.74 1.08 98.64
78 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 98.62
79 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 98.52
80 INT175691 Gene_expression of Lcat 6 0.57 7.87 0.21 98.50
81 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 98.36
82 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 98.32
83 INT229940 Positive_regulation of amd 10 0.49 27.97 0.15 98.20
84 INT11506 Binding of MUC16 20 0.48 22.89 1.03 98.12
85 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 98.10
86 INT197512 Gene_expression of ABCA4 19 0.75 7.08 0.57 98.10
87 INT117232 Localization of COL2A1 11 0.72 7.34 1.3 97.80
88 INT197511 Localization of ABCA4 3 0.68 1.47 0.03 97.80
89 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 97.76
90 INT120828 Localization of CXCL10 29 0.68 18.01 12.17 97.56
91 INT340828 Regulation of ADCY10 1 0.06 5.17 0.11 97.28
92 INT146549 Negative_regulation of Ephx2 10 0.54 3.55 0.74 97.04
93 INT272274 Localization of NARFL 24 0.60 27.55 1.18 96.96
94 INT73252 Positive_regulation of Mthfd1 124 0.59 59.48 18.35 96.88
95 INT157816 Positive_regulation of Positive_regulation of Mthfd1 5 0.33 3.73 1.93 96.88
96 INT213967 Positive_regulation of Localization of Mthfd1 4 0.30 2.52 0.46 96.88
97 INT233398 Localization of TIMP3 2 0.45 1.31 0.26 96.84
98 INT183817 Localization of BEST1 6 0.26 5.22 0.16 96.84
99 INT227549 Gene_expression of Tshr 4 0.35 4.32 0.24 96.70
100 INT311602 Positive_regulation of Binding of CXCL10 1 0.38 2.79 0.57 96.68
101 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 96.68
102 INT257448 Negative_regulation of Localization of MUC5AC 2 0.35 2.57 0 96.64
103 INT173021 Localization of MUC5AC 14 0.70 10.73 0.91 96.64
104 INT7125 Gene_expression of PLA2G2A 47 0.78 42.12 7.83 96.60
105 INT2037 Negative_regulation of EGF 30 0.59 15.05 6.81 96.56
106 INT148085 Binding of CXCL10 14 0.32 10.22 3.81 96.28
107 INT99777 Positive_regulation of Localization of Cxcl10 4 0.50 3.71 1.24 96.24
108 INT340809 Gene_expression of Btla 1 0.77 27.14 1.69 96.24
109 INT99778 Localization of Cxcl10 12 0.75 14.24 3.91 96.08
110 INT7130 Localization of PLA2G2A 32 0.80 20.4 5.05 96.04
111 INT228770 Gene_expression of amd 16 0.57 21.49 1.05 95.84
112 INT242922 Positive_regulation of Gene_expression of amd 2 0.43 5.99 0.1 95.84
113 INT64052 Positive_regulation of FGFR1 26 0.52 28.47 6.36 95.80
114 INT30014 Positive_regulation of HPSE 22 0.70 20.91 4.09 95.80
115 INT9473 Binding of MUC1 66 0.48 46.77 2.36 95.80
116 INT75540 Positive_regulation of TH1L 62 0.67 43.45 15.02 95.80
117 INT342238 Negative_regulation of ARC 1 0.32 2.05 0 95.64
118 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 95.36
119 INT17962 Regulation of Car2 124 0.41 33.98 22.71 95.36
120 INT188588 Localization of Mthfd1 20 0.49 9.19 4.37 95.36
121 INT5160 Localization of PTAFR 61 0.80 42.6 19.16 95.28
122 INT23564 Negative_regulation of Car2 103 0.50 27.28 21.86 95.24
123 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34 94.96
124 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 94.64
125 INT219224 Gene_expression of Ighv10-3 1 0.03 12.91 0.07 94.52
126 INT18681 Gene_expression of Thy1 80 0.71 38.8 5.23 94.28
127 INT75932 Binding of Csf2 45 0.37 33.2 8.01 93.92
128 INT353098 Phosphorylation of amd 1 0.65 1.26 0 93.76
129 INT157461 Binding of CX3CR1 3 0.36 6.72 2.67 93.64
130 INT47075 Positive_regulation of Ptger2 142 0.70 78.55 25.47 93.52
131 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 93.52
132 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 93.52
133 INT108780 Positive_regulation of Gene_expression of Ptger2 94 0.49 59.71 16.22 93.52
134 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 93.52
135 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03 93.48
136 INT60700 Gene_expression of Itgax 93 0.71 51.89 6.57 93.48
137 INT227548 Negative_regulation of Localization of Ppara 7 0.38 4.1 1.17 93.44
138 INT194462 Localization of Ppara 94 0.78 68.33 12.09 93.44
139 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 92.96
140 INT227550 Negative_regulation of Localization of Tshr 1 0.19 0.98 0.25 92.96
141 INT40914 Localization of Tshr 2 0.63 0.98 0.73 92.96
142 INT4535 Localization of PROC 106 0.73 76.24 21.1 92.88
143 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 92.76
144 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 92.76
145 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68 92.76
146 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56 92.68
147 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 92.64
148 INT121663 Gene_expression of CXCR3 76 0.77 50.96 30.62 92.56
149 INT78773 Regulation of PLA2G2A 11 0.61 9.76 1.91 92.44
150 INT265449 Gene_expression of Aire 10 0.67 9.18 1.8 92.32
151 INT92678 Positive_regulation of Ecm1 30 0.09 28.41 3.68 92.28
152 INT157466 Gene_expression of CX3CR1 14 0.76 20.6 10.76 92.24
153 INT28420 Gene_expression of Ptgds 59 0.78 31.72 12.67 91.88
154 INT3165 Gene_expression of LYZ 25 0.65 16.72 5.16 91.80
155 INT89966 Negative_regulation of Fas 26 0.58 24.83 3.5 91.76
156 INT107302 Negative_regulation of Gene_expression of Fasl 7 0.42 8.52 2.54 91.76
157 INT133766 Negative_regulation of Fasl 11 0.56 11.28 2.27 91.76
158 INT89967 Negative_regulation of Gene_expression of Fas 19 0.58 19.28 1.1 91.76
159 INT178127 Positive_regulation of Gene_expression of EDNRB 7 0.51 5.24 0.78 91.76
160 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 91.72
161 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 91.68
162 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 91.36
163 INT173545 Gene_expression of LR 16 0.09 13.1 0.69 91.36
164 INT346641 Protein_catabolism of TNMD 1 0.57 2.1 0 91.08
165 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11 91.04
166 INT119523 Gene_expression of EDNRB 32 0.75 26.47 5.75 90.60
167 INT265440 Gene_expression of Abpe 2 0.19 10.64 1.07 90.60
168 INT177551 Negative_regulation of Tg(CAG-EGFP)D4Nagy 31 0.37 11.16 2.65 90.28
169 INT200752 Negative_regulation of Tfam 1 0.13 0.3 0.03 90.28
170 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63 90.24
171 INT43723 Regulation of Vegfa 9 0.34 4.96 2.28 89.76
172 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19 89.72
173 INT16389 Gene_expression of Plg 80 0.67 36.88 6.74 89.72
174 INT7127 Positive_regulation of Gene_expression of PLA2G2A 16 0.69 17.11 2.63 89.60
175 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 89.32
176 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 89.12
177 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 88.92
178 INT24978 Binding of SFTPA1 22 0.47 15.09 7.76 88.80
179 INT20371 Gene_expression of Cd8a 125 0.60 67.59 8.97 88.56
180 INT255237 Positive_regulation of Gene_expression of MCDR1 1 0.08 0.4 0 88.48
181 INT122041 Binding of Ppara 308 0.48 189.17 51.48 88.40
182 INT139863 Binding of amd 27 0.41 41.3 0.91 88.32
183 INT59175 Localization of TNMD 4 0.70 4.14 0.71 88.24
184 INT198453 Negative_regulation of MUC5AC 12 0.58 12.96 1.38 88.24
185 INT58449 Binding of Mthfd1 47 0.47 22.02 10.29 88.08
186 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 88.00
187 INT10705 Binding of Il1b 9 0.36 2.8 5.53 87.84
188 INT268704 Positive_regulation of ARC 2 0.38 2.42 0 87.68
189 INT255234 Gene_expression of MCDR1 1 0.11 1.39 0 87.60
190 INT211984 Regulation of Binding of Ppara 11 0.45 9.55 1.87 87.40
191 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 87.36
192 INT291359 Binding of Cx3cl1 2 0.36 2.31 1.13 87.24
193 INT260525 Gene_expression of AMD1 25 0.66 24.58 1.32 87.00
194 INT139862 Negative_regulation of amd 8 0.35 10.15 0.6 87.00
195 INT19047 Localization of SLC25A4 5 0.73 2.73 0.57 86.08
196 INT302682 Localization of POLG2 1 0.67 1 0.11 86.08
197 INT302693 Localization of C10orf2 1 0.59 1 0.11 86.08
198 INT302695 Negative_regulation of Localization of C10orf2 1 0.33 1 0.11 86.08
199 INT302706 Negative_regulation of Localization of POLG2 1 0.38 1 0.11 86.08
200 INT302679 Negative_regulation of Localization of POLG 1 0.39 0.99 0.11 86.08
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