D:Familial Amyloidosis

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pChart

Disease Term
Synonyms Amyloidoses Familial, Amyloidoses Hereditary, AMYLOIDOSIS HEREDITARY, Familial Amyloidoses, HEREDITARY AMYLOIDOSES, Hereditary Amyloidosis
Documents 28
Hot Single Events 2
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Familial Amyloidosis. They are ordered first by their relevance to Familial Amyloidosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT224922 Binding of FAP and TARM1 1 0.06 1.4 0.06 46.12
2 INT224921 Binding of TTR and TARM1 1 0.06 1.06 0 16.36
3 INT273136 Binding of CHED1 and VSX1 1 0.15 0.12 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Familial Amyloidosis. They are ordered first by their pain relevance and then by number of times they were reported in Familial Amyloidosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT39212 Binding of Ttr 14 0.48 9.62 2.31 99.98
2 INT224924 Binding of TARM1 4 0.18 3.42 0.39 99.92
3 INT56342 Gene_expression of TTR 34 0.78 16.5 2.05 68.04
4 INT67048 Gene_expression of ITGA4 58 0.75 28.93 10.16 66.24
5 INT192423 Positive_regulation of TARM1 5 0.34 10.77 0.51 62.88
6 INT16150 Positive_regulation of NKG7 10 0.69 10.26 1.73 50.56
7 INT37661 Negative_regulation of SERPINC1 48 0.59 38.6 4.77 44.12
8 INT232943 Binding of KRT12 3 0.47 0.88 0 15.40
9 INT232980 Binding of KRT3 2 0.29 0.43 0 15.40
10 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
11 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 5.00
12 INT11508 Positive_regulation of TGFBI 24 0.70 19.81 15.78 5.00
13 INT53189 Gene_expression of VSX1 32 0.69 10.59 7.21 5.00
14 INT6891 Binding of TTR 72 0.48 22.81 6.51 5.00
15 INT55655 Gene_expression of DCN 17 0.75 7.98 5.98 5.00
16 INT35609 Negative_regulation of F10 37 0.57 17.15 4.41 5.00
17 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 5.00
18 INT52678 Positive_regulation of VSX1 15 0.42 3.94 3.64 5.00
19 INT2117 Regulation of VSX1 15 0.30 3.38 3.38 5.00
20 INT4596 Positive_regulation of SCD 18 0.42 22.59 3.26 5.00
21 INT44873 Negative_regulation of LCAT 16 0.59 6.92 3.13 5.00
22 INT71794 Binding of SERPINC1 17 0.39 10.5 2.64 5.00
23 INT44223 Positive_regulation of TTR 10 0.70 10.98 1.95 5.00
24 INT2116 Negative_regulation of VSX1 29 0.36 10.67 1.89 5.00
25 INT85084 Gene_expression of KRT19 66 0.73 42.56 1.82 5.00
26 INT121335 Localization of SCD 10 0.68 6.81 1.51 5.00
27 INT18844 Binding of IAPP 11 0.36 11.01 1.45 5.00
28 INT126370 Localization of VSX1 6 0.56 1.7 1.28 5.00
29 INT186483 Negative_regulation of MYOM2 3 0.04 2.92 0.79 5.00
30 INT59175 Localization of TNMD 4 0.70 4.14 0.71 5.00
31 INT60115 Transcription of F8 2 0.08 3.05 0.58 5.00
32 INT4597 Regulation of SCD 5 0.39 2.25 0.5 5.00
33 INT189634 Regulation of DCN 3 0.25 1.69 0.49 5.00
34 INT9801 Regulation of TTR 3 0.45 1.4 0.48 5.00
35 INT186480 Positive_regulation of Transcription of F8 1 0.06 2.08 0.4 5.00
36 INT186482 Regulation of Transcription of ANGPTL5 1 0.03 2.05 0.4 5.00
37 INT165342 Gene_expression of TGFBI 13 0.59 5.81 0.39 5.00
38 INT186481 Transcription of ANGPTL5 1 0.04 2.04 0.39 5.00
39 INT273158 Binding of COL8A2 1 0.33 2.02 0.22 5.00
40 INT218762 Localization of ZEB1 2 0.65 0.09 0.2 5.00
41 INT273145 Negative_regulation of COL8A2 1 0.40 0.83 0.06 5.00
42 INT273155 Gene_expression of COL8A2 1 0.53 0.74 0.05 5.00
43 INT273142 Gene_expression of Smc3 1 0.09 0.35 0 5.00
44 INT273143 Negative_regulation of Tat 1 0.01 2.3 0 5.00
45 INT273144 Binding of CHED1 1 0.19 1.7 0 5.00
46 INT273146 Positive_regulation of Binding of TNMD 1 0.02 0.21 0 5.00
47 INT273147 Binding of TBCD 1 0.05 0 0 5.00
48 INT273148 Localization of LCAT 1 0.38 0.91 0 5.00
49 INT273149 Localization of GCDH 1 0.06 0.77 0 5.00
50 INT273150 Regulation of CHED1 1 0.24 0.09 0 5.00
51 INT273151 Binding of GCDH 1 0.04 0.25 0 5.00
52 INT273152 Positive_regulation of Localization of LCAT 1 0.26 0.91 0 5.00
53 INT273153 Positive_regulation of CHED1 1 0.27 1.53 0 5.00
54 INT273154 Positive_regulation of Localization of SCD 1 0.03 0.94 0 5.00
55 INT273156 Gene_expression of SLC4A11 1 0.41 0.84 0 5.00
56 INT273157 Localization of COL8A2 1 0.26 0.09 0 5.00
57 INT273159 Gene_expression of CHED1 1 0.36 1.83 0 5.00
58 INT273160 Binding of TNMD 4 0.42 1.72 0 5.00
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