D:Familial Periodic Paralyses

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pChart

Disease Term
Synonyms Familial Periodic Paralysis, Normokalemic Periodic Paralyses, Normokalemic Periodic Paralysis, PARALYSES NORMOKALEMIC PERIODIC, Paralysis Familial Periodic, Paralysis Normokalemic Periodic, Periodic Paralyses Familial, Periodic Paralyses Normokalemic, Periodic Paralysis Familial, Periodic Paralysis Normokalemic
Documents 9
Hot Single Events 1
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Familial Periodic Paralyses. They are ordered first by their relevance to Familial Periodic Paralyses and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT315030 Binding of Cav1 and Tmie 1 0.03 0.25 0.14 5.00
2 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14 5.00
3 INT315034 Ass1 Positive_regulation of Cacna1f 1 0.00 0 0.03 5.00
4 INT314986 Ins1 Negative_regulation of CACNA1S 1 0.00 0.08 0 5.00
5 INT315029 Binding of Calm3 and Cacna1f 1 0.04 0 0 5.00
6 INT315031 Binding of Cacna1f and Vsig2 1 0.02 0 0 5.00
7 INT315033 Binding of Calm3 and Vsig2 1 0.00 0 0 5.00
8 INT315035 Binding of NAE1 and Cav1 1 0.01 0.7 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Familial Periodic Paralyses. They are ordered first by their pain relevance and then by number of times they were reported in Familial Periodic Paralyses. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT315017 Regulation of Psmc1 1 0.06 0.49 0 88.60
2 INT315004 Positive_regulation of Psmc1 1 0.10 0.85 0 76.24
3 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97 61.44
4 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 24.64
5 INT25170 Positive_regulation of Localization of Car2 78 0.67 15.25 11.24 24.64
6 INT170503 Positive_regulation of Localization of Tmie 11 0.29 3.27 0.61 24.64
7 INT17561 Localization of Car2 303 0.79 60.95 44.52 22.68
8 INT170507 Localization of Tmie 27 0.43 6.25 1.31 22.48
9 INT97367 Gene_expression of Nav1 243 0.78 132.97 286.66 5.00
10 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
11 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
12 INT100965 Positive_regulation of Nav1 85 0.70 37.74 75.35 5.00
13 INT97368 Negative_regulation of Nav1 62 0.59 41.56 60.27 5.00
14 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
15 INT111051 Negative_regulation of Nav1 64 0.59 25.51 47.27 5.00
16 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 5.00
17 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
18 INT102429 Negative_regulation of Gene_expression of Nav1 19 0.59 20.09 28.09 5.00
19 INT11014 Phosphorylation of CREB1 72 0.81 26.35 25.64 5.00
20 INT170444 Binding of Gopc 172 0.39 45.05 20.71 5.00
21 INT145971 Localization of Nav1 20 0.81 10.3 18.11 5.00
22 INT170051 Positive_regulation of Gene_expression of Gopc 150 0.43 56.75 16.93 5.00
23 INT170504 Positive_regulation of Gene_expression of Car2 60 0.41 19.1 8.45 5.00
24 INT87271 Positive_regulation of Phosphorylation of CREB1 27 0.66 12.87 7.91 5.00
25 INT134864 Binding of Calm3 20 0.27 1.86 6.86 5.00
26 INT74051 Negative_regulation of Localization of Car2 27 0.38 9.58 5.1 5.00
27 INT14091 Binding of Vsig2 8 0.42 3.21 3.91 5.00
28 INT18396 Positive_regulation of Ryr1 10 0.58 2.45 3.38 5.00
29 INT92632 Gene_expression of Vsig2 48 0.50 19.93 3.04 5.00
30 INT30171 Gene_expression of Calm3 13 0.73 0.58 2.96 5.00
31 INT67737 Negative_regulation of Pam 6 0.51 4.08 2.19 5.00
32 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61 5.00
33 INT170511 Regulation of Localization of Car2 11 0.21 2.18 1.09 5.00
34 INT116831 Binding of Ryr1 11 0.47 0.12 0.9 5.00
35 INT112090 Negative_regulation of Gene_expression of Cav1 8 0.57 3.5 0.78 5.00
36 INT236517 Gene_expression of Cacna1f 8 0.65 5.18 0.77 5.00
37 INT70104 Positive_regulation of CACNA1S 6 0.47 5.92 0.68 5.00
38 INT248968 Regulation of Csn2 2 0.20 0.09 0.68 5.00
39 INT315028 Regulation of Cav2 2 0.43 0.86 0.54 5.00
40 INT220504 Positive_regulation of Gene_expression of Cav1 11 0.39 6.26 0.43 5.00
41 INT262546 Positive_regulation of Binding of Calm3 2 0.11 0.3 0.39 5.00
42 INT220506 Binding of Cav1 13 0.45 5.46 0.38 5.00
43 INT315006 Regulation of Localization of Tmie 2 0.04 0.26 0.37 5.00
44 INT315011 Gene_expression of Cacna1d 1 0.57 4.47 0.29 5.00
45 INT135954 Positive_regulation of Phosphorylation of Cav1 2 0.40 0.64 0.22 5.00
46 INT135956 Phosphorylation of Cav1 5 0.64 2.24 0.22 5.00
47 INT273279 Negative_regulation of Localization of Tmie 2 0.07 1.72 0.2 5.00
48 INT220497 Regulation of Gene_expression of Cav1 4 0.36 1.84 0.18 5.00
49 INT315025 Gene_expression of Cacna1s 3 0.48 2.3 0.18 5.00
50 INT315024 Positive_regulation of Cacna1f 1 0.41 0.5 0.17 5.00
51 INT315022 Regulation of Cacna1d 1 0.20 0.32 0.16 5.00
52 INT145253 Negative_regulation of Cav1 9 0.46 3.02 0.15 5.00
53 INT314985 Positive_regulation of Negative_regulation of Pam 1 0.05 2.1 0.15 5.00
54 INT214975 Localization of Cav1 7 0.75 2.7 0.13 5.00
55 INT315023 Transcription of Cacna1d 1 0.50 0.26 0.13 5.00
56 INT170514 Gene_expression of Ryr1 4 0.49 0.56 0.12 5.00
57 INT315016 Negative_regulation of Csn2 1 0.19 0 0.12 5.00
58 INT315018 Positive_regulation of Gene_expression of Csn2 1 0.22 0 0.12 5.00
59 INT315026 Gene_expression of Csn2 1 0.30 0.24 0.12 5.00
60 INT315027 Positive_regulation of Gene_expression of Cacna1f 1 0.41 0.27 0.12 5.00
61 INT314984 Positive_regulation of Cd2ap 1 0.01 0.75 0.11 5.00
62 INT315005 Binding of Hmgcs2 1 0.11 0.73 0.11 5.00
63 INT236521 Negative_regulation of Cacna1f 2 0.36 0.07 0.09 5.00
64 INT315020 Positive_regulation of Gene_expression of Cacna1d 1 0.51 2.24 0.08 5.00
65 INT220491 Transcription of Cav1 2 0.54 1.1 0.07 5.00
66 INT315015 Regulation of Gene_expression of Cacna1d 1 0.20 0.67 0.07 5.00
67 INT315009 Regulation of Phosphorylation of Cav1 1 0.36 0.2 0.05 5.00
68 INT300713 Regulation of Localization of Cav1 2 0.42 1.37 0.04 5.00
69 INT315008 Negative_regulation of Gene_expression of Cacna1d 1 0.31 0.73 0.04 5.00
70 INT315012 Positive_regulation of Binding of Vsig2 1 0.04 0.09 0.04 5.00
71 INT207781 Gene_expression of CACNA1S 3 0.63 0.9 0.03 5.00
72 INT271733 Gene_expression of Psmc1 2 0.65 1.91 0.03 5.00
73 INT236516 Regulation of Cacna1f 3 0.44 0.23 0 5.00
74 INT236525 Binding of Cacna1f 5 0.39 0.07 0 5.00
75 INT314978 Binding of Lp1 1 0.09 0.25 0 5.00
76 INT314979 Negative_regulation of Localization of Lp1 1 0.10 0.1 0 5.00
77 INT314980 Localization of Lp1 1 0.18 0 0 5.00
78 INT315007 Positive_regulation of Cacna1d 1 0.42 0.55 0 5.00
79 INT315010 Negative_regulation of Transcription of Cav1 1 0.34 0.21 0 5.00
80 INT315013 Negative_regulation of Binding of Vsig2 1 0.04 0 0 5.00
81 INT315019 Regulation of Binding of Cacna1f 1 0.37 0.07 0 5.00
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