D:Fatty Liver

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Disease Term
Synonyms LIVER FATTY, Liver Fatty Streak, Liver Steatosis, Nafld, Non Alcoholic Fatty Liver Disease, Nonalcoholic Fatty Liver Disease, Steatosis Liver
Documents 241
Hot Single Events 200
Hot Interactions 32

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Fatty Liver. They are ordered first by their relevance to Fatty Liver and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT301615 Binding of Cyp2e1 and Samsn1 1 0.02 2.42 0.18 100.00
2 INT260727 Binding of Gfm1 and NAFLD2 1 0.00 1.05 0 100.00
3 INT260726 Positive_regulation of Binding of Gfm1 and NAFLD2 1 0.00 1.05 0 100.00
4 INT260728 Binding of Samsn1 and NAFLD2 1 0.00 1.15 0.05 100.00
5 INT190683 Binding of A2M and INS 4 0.11 4.97 0.32 98.96
6 INT301620 Positive_regulation of Binding of Ros1 and Scd1 1 0.03 0.41 0 98.72
7 INT301634 Positive_regulation of Binding of Ros1 and Cyb5 1 0.00 0.41 0 98.72
8 INT301633 Binding of Ros1 and Cyb5 1 0.00 0.41 0 98.52
9 INT301652 Binding of Ros1 and Scd1 1 0.02 0.41 0 98.52
10 INT348012 Samsn1 Positive_regulation of Vps54 1 0.00 1.93 0.15 97.60
11 INT255744 Binding of hs and Ptch1 1 0.06 1.32 0 97.32
12 INT301660 Ppara Regulation of Gene_expression of CYP4A11 1 0.24 0.65 0.09 96.96
13 INT301663 Ppara Regulation of CYP4A11 1 0.14 0.65 0.09 96.96
14 INT335126 Ptgs2 Positive_regulation of Gene_expression of PPARA 1 0.24 0.72 0.25 96.96
15 INT301622 Binding of Fabp4 and fa 1 0.01 0.45 0.03 95.92
16 INT301643 Binding of Dbi and fa 1 0.05 0.45 0.03 95.56
17 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34 94.24
18 INT227339 Binding of TNF and Ins1 1 0.28 4.08 0.31 93.36
19 INT100783 Binding of CYP2B6 and CYP3A4 2 0.17 2 0.77 92.28
20 INT242960 Binding of Ins1 and Ffar1 1 0.19 1.33 0.04 91.64
21 INT301497 UBXN11 Negative_regulation of CYP4F3 1 0.37 0.69 0.05 91.60
22 INT301496 PPA1 Negative_regulation of CYP4F3 1 0.01 0.69 0.05 91.28
23 INT199212 Binding of IGFBP1 and INS 1 0.05 1.77 0.04 88.56
24 INT190684 Binding of A2M and IGF1 1 0.16 1.54 0.1 86.24
25 INT301667 Tlr4 Positive_regulation of Gene_expression of CYBB 1 0.01 0.84 0.03 85.96
26 INT301662 Binding of Tlr4 and Positive_regulation of Gene_expression of CYBB 1 0.01 0.84 0.03 85.96
27 INT127966 GPT Positive_regulation of SLC17A5 1 0.50 1.81 0.14 84.80
28 INT36328 Binding of AMPD1 and Hmgcl 1 0.01 1.02 0 82.56
29 INT252801 PPP2R4 Regulation of Positive_regulation of CREB1 1 0.01 2.71 0.04 82.40
30 INT252780 Positive_regulation of CREB1 Positive_regulation of PPP2R4 1 0.01 2.71 0.04 82.40
31 INT301640 Positive_regulation of Cyp2e1 Positive_regulation of Gene_expression of Ros1 1 0.03 0.25 0 80.32
32 INT252818 PPP2R4 Regulation of Positive_regulation of DDIT3 1 0.04 3.07 0.04 80.16
33 INT242961 Ffar1 Regulation of Localization of Ins1 1 0.23 2.08 0.08 79.00
34 INT242959 Ffar1 Positive_regulation of Localization of Ins1 1 0.26 0.97 0 79.00
35 INT252821 Binding of CD4 and IL12A 1 0.02 1.36 0.19 75.92
36 INT252817 Binding of CD8A and IL12A 1 0.02 1.36 0.19 75.92
37 INT252788 Binding of IL12A and IL18 1 0.01 1.33 0.19 75.92
38 INT301661 Binding of CYP2B6 and Ros1 1 0.02 0.64 0.04 75.76
39 INT211576 Vldlr Positive_regulation of Lpl 1 0.38 0.24 0 74.56
40 INT255741 Ptch1 Positive_regulation of Phosphorylation of Ins1 1 0.09 2.21 0 71.60
41 INT249760 Positive_regulation of Cnr1 Negative_regulation of Gene_expression of Adipoq 1 0.20 0.81 0.22 71.28
42 INT301632 Binding of Dbi and Fabp1 1 0.13 0.49 0.07 69.68
43 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 68.44
44 INT343834 Binding of CD14 and IRF6 1 0.02 2.08 0.9 68.44
45 INT343859 Binding of IRF6 and TBCE 1 0.01 1.1 0.51 68.44
46 INT343860 Binding of CD14 and TBCE 1 0.03 1.1 0.51 68.44
47 INT330620 S100a8 Positive_regulation of Positive_regulation of TNF 1 0.03 1.92 0.32 66.40
48 INT255732 Ptch1 Positive_regulation of hs 1 0.06 1.26 0 65.44
49 INT252842 ENOPH1 Positive_regulation of Gene_expression of Ddit3 1 0.06 2.42 0 64.92
50 INT252805 ENOPH1 Positive_regulation of Gene_expression of ESR1 1 0.00 2.46 0 64.92
51 INT252792 ENOPH1 Positive_regulation of Gene_expression of DDIT3 1 0.03 2.42 0 64.92
52 INT339696 Binding of PPARA and TRO 1 0.10 0.74 0 64.32
53 INT249759 Positive_regulation of Cnr1 Positive_regulation of Lpl 1 0.29 0.74 0.21 63.52
54 INT301668 Ltb4r1 Positive_regulation of Gene_expression of IL8 1 0.00 0.9 0.27 63.32
55 INT183302 Tchol1 Negative_regulation of Lipg 1 0.00 0.52 0.05 63.16
56 INT301671 Ltc4s Positive_regulation of Gene_expression of IL8 1 0.00 0.9 0.27 63.00
57 INT304208 Ufm1 Positive_regulation of Fas 1 0.01 0.51 0 61.44
58 INT252779 Binding of ESR1 and RAF1 1 0.01 2.03 0.11 59.40
59 INT252778 RAF1 Positive_regulation of Positive_regulation of ROS1 1 0.04 2.05 0.11 59.40
60 INT301621 Ppara Positive_regulation of Gene_expression of Mttp 1 0.22 0.59 0 57.96
61 INT301635 Ppara Positive_regulation of Gene_expression of Fabp1 1 0.26 0.29 0 57.96
62 INT301670 Binding of CYP4F2 and Cyp4f18 1 0.02 1.04 0.27 57.84
63 INT301656 Ins1 Positive_regulation of Srebf1 1 0.02 0.73 0.07 57.36
64 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36 56.40
65 INT252807 Binding of ACO1 and TFRC 1 0.01 1.83 0 56.04
66 INT301623 Ins1 Positive_regulation of Slc27a2 1 0.01 0.37 0.07 56.00
67 INT301658 Ins1 Positive_regulation of Slc27a4 1 0.01 0.37 0.07 56.00
68 INT252791 Binding of IREB2 and TFRC 1 0.02 1.82 0 55.64
69 INT339702 TRO Positive_regulation of CD36 1 0.08 1.06 0 52.16
70 INT310275 Negative_regulation of Binding of Adipoq and Ins1 1 0.19 1.14 0.09 50.00
71 INT310274 Binding of Adipoq and Ins1 1 0.21 1.14 0.09 50.00
72 INT310280 Gpt Positive_regulation of SLPI 1 0.30 0.43 0 50.00
73 INT310276 Gcg Positive_regulation of Localization of Ins1 1 0.25 0 0 50.00
74 INT310279 Tmprss11d Positive_regulation of SLPI 1 0.18 0.43 0 50.00
75 INT348033 Fndc3b Positive_regulation of Vps54 1 0.00 1.87 0.03 48.72
76 INT301664 UBXN11 Positive_regulation of Negative_regulation of Cpt1a 1 0.27 0.37 0 45.64
77 INT301657 Binding of Dbi and Ppara 1 0.26 0.23 0 45.60
78 INT301650 Ins1 Positive_regulation of Dbi 1 0.02 0.23 0 45.60
79 INT226787 Trglyd Positive_regulation of Lbp 1 0.04 1.67 0.07 37.68
80 INT226786 Scl1 Positive_regulation of Lbp 1 0.04 1.68 0.07 37.68
81 INT182886 Ros1 Positive_regulation of Mapk8 3 0.09 2.3 0.12 37.36
82 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91 34.28
83 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91 34.28
84 INT335132 PPARA Positive_regulation of Cyp4x1 1 0.25 0 0.08 31.92
85 INT335021 Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.53 1.49 0.21 31.36
86 INT335020 Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.62 0.82 0.18 31.36
87 INT301629 Ins1 Positive_regulation of Mlxipl 1 0.00 0.36 0 31.04
88 INT301653 Mlxipl Positive_regulation of Gene_expression of Scd1 1 0.08 0.5 0.05 26.96
89 INT301655 Irs1 Negative_regulation of Transcription of Pck1 1 0.03 0.65 0.08 26.48
90 INT301649 Irs1 Negative_regulation of Transcription of G6pc 1 0.05 0.65 0.08 26.48
91 INT301641 Irs2 Negative_regulation of Transcription of Pck1 1 0.03 0.65 0.08 26.08
92 INT301628 Irs2 Negative_regulation of Transcription of G6pc 1 0.04 0.65 0.08 26.08
93 INT301627 Binding of Fabp1 and Ppara 1 0.21 0.49 0.04 25.68
94 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31 25.00
95 INT253122 Ins1 Positive_regulation of Akt1 2 0.15 1.81 0.14 25.00
96 INT255754 Negative_regulation of Ins1 Positive_regulation of Akt1 1 0.14 1.73 0.1 25.00
97 INT255735 Ptch1 Positive_regulation of Phosphorylation of Akt1 1 0.27 2.83 0 25.00
98 INT301637 Positive_regulation of Ros1 Positive_regulation of Phosphorylation of Ins1 1 0.00 0.91 0.1 22.48
99 INT301619 Positive_regulation of Irs1 Positive_regulation of Gene_expression of Srebf1 1 0.10 0.67 0.08 21.40
100 INT239188 Proc Positive_regulation of Akt1 3 0.01 1.72 0 20.72
101 INT301638 Ppara Regulation of Slc27a2 1 0.30 0.29 0.14 19.92
102 INT240944 Akt1 Positive_regulation of Phosphorylation of Foxo1 1 0.22 0.06 0 19.04
103 INT301646 Srebf1 Negative_regulation of Gene_expression of Irs2 1 0.08 0.62 0.08 18.68
104 INT240903 Mapk8 Positive_regulation of Ros1 2 0.09 1.01 0.1 16.96
105 INT301639 Positive_regulation of Mlxipl Positive_regulation of Gene_expression of Pklr 1 0.03 0.52 0 16.00
106 INT314624 Ex Regulation of GCG 1 0.01 0.67 0 13.20
107 INT314621 Ex Regulation of INS 1 0.06 0.67 0 12.48
108 INT227303 Zbp1 Regulation of Transcription of Baat 1 0.09 1.43 0.08 11.68
109 INT227301 Zbp1 Regulation of Transcription of Ucp1 1 0.19 1.42 0.08 11.68
110 INT227304 Zbp1 Regulation of Transcription of Ucp2 1 0.17 1.43 0.08 11.68
111 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95 5.00
112 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95 5.00
113 INT288731 Binding of Got1 and Gpt 1 0.23 1.25 1.61 5.00
114 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32 5.00
115 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11 5.00
116 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 5.00
117 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89 5.00
118 INT343847 IRF6 Positive_regulation of TBCE 1 0.01 1.11 0.87 5.00
119 INT343829 TLR1 Positive_regulation of TBCE 1 0.03 0.96 0.85 5.00
120 INT239671 Binding of Ccl2 and Gtf3a 1 0.02 1.34 0.79 5.00
121 INT11684 Binding of CSF2 and IL3 6 0.36 3.3 0.72 5.00
122 INT335054 LPL Positive_regulation of Localization of VLDLR 1 0.04 1.48 0.67 5.00
123 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66 5.00
124 INT308668 Akt1 Positive_regulation of Nos3 3 0.05 4.61 0.65 5.00
125 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63 5.00
126 INT252772 ELANE Regulation of Gene_expression of CCL2 1 0.05 2.16 0.62 5.00
127 INT252826 ROS1 Regulation of Gene_expression of CCL2 1 0.20 2.17 0.62 5.00
128 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6 5.00
129 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54 5.00
130 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51 5.00
131 INT343825 IRF6 Regulation of Gene_expression of FUT1 1 0.00 1.74 0.5 5.00
132 INT288729 Positive_regulation of Binding of Got1 and Gpt 1 0.25 0.61 0.49 5.00
133 INT343846 MAPK1 Positive_regulation of FOS 1 0.04 1.29 0.44 5.00
134 INT343853 IRF6 Positive_regulation of PECAM1 1 0.00 0.53 0.43 5.00
135 INT283714 Positive_regulation of Binding of Id2 and Homer1 1 0.08 1.34 0.42 5.00
136 INT283713 Binding of Id2 and Homer1 1 0.06 1.34 0.42 5.00
137 INT343916 Hspa1a Positive_regulation of Gene_expression of TNF 1 0.16 1.17 0.41 5.00
138 INT343919 Hspa1a Positive_regulation of Gene_expression of IL6 1 0.02 1.17 0.4 5.00
139 INT343907 Hspa1a Positive_regulation of Gene_expression of Cxcl2 1 0.01 1.17 0.4 5.00
140 INT343844 Binding of IRF6 and LY96 1 0.01 1.03 0.4 5.00
141 INT348031 Binding of Irf3 and Tbk1 1 0.17 2.82 0.4 5.00
142 INT295478 IRF6 Positive_regulation of Positive_regulation of TLR4 2 0.20 0.78 0.39 5.00
143 INT329799 Binding of CD14 and LY96 2 0.04 1.02 0.39 5.00
144 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 0.23 4.34 0.37 5.00
145 INT343912 Fgg Positive_regulation of Gene_expression of IL6 1 0.00 0.83 0.35 5.00
146 INT343857 Binding of ABCC8 and LY96 1 0.02 0.96 0.34 5.00
147 INT348016 Binding of Mapk8 and Mapk8ip3 1 0.04 2.09 0.32 5.00
148 INT307215 Negative_regulation of Prkca Negative_regulation of Ppara 1 0.09 0.21 0.3 5.00
149 INT122575 Akt1 Positive_regulation of Phosphorylation of Nos3 4 0.37 3.89 0.29 5.00
150 INT335027 Binding of Vdr and Fgf23 1 0.24 0.34 0.29 5.00
151 INT335134 PPARA Negative_regulation of Cyp1a1 1 0.47 0 0.28 5.00
152 INT301666 Binding of CYP4F2 and Ltb4r1 1 0.02 0.57 0.28 5.00
153 INT343856 Binding of S100A9 and ABCC8 1 0.04 0.9 0.28 5.00
154 INT252806 F2 Positive_regulation of Gene_expression of CCL2 1 0.01 0.8 0.27 5.00
155 INT343832 Positive_regulation of EDA Positive_regulation of TLR4 1 0.11 0.43 0.27 5.00
156 INT335130 PPARA Positive_regulation of Cyp8b1 1 0.37 0 0.27 5.00
157 INT335049 PPARA Negative_regulation of Gene_expression of CYP7B1 1 0.27 0 0.26 5.00
158 INT252794 Binding of IL8 and TNF 1 0.02 0.75 0.25 5.00
159 INT252795 IL8 Positive_regulation of Positive_regulation of FOS 1 0.01 0.75 0.25 5.00
160 INT252815 Binding of CCL5 and TNF 1 0.02 0.75 0.25 5.00
161 INT252822 CCL2 Positive_regulation of Positive_regulation of FOS 1 0.04 0.75 0.25 5.00
162 INT252804 TNF Regulation of Positive_regulation of FOS 1 0.01 0.76 0.25 5.00
163 INT252786 CCL2 Regulation of Positive_regulation of FOS 1 0.05 0.75 0.25 5.00
164 INT252816 IL8 Regulation of Positive_regulation of FOS 1 0.01 0.75 0.25 5.00
165 INT252793 TNF Positive_regulation of Positive_regulation of FOS 1 0.02 0.76 0.25 5.00
166 INT343864 EDA Positive_regulation of Gene_expression of TLR4 1 0.11 0.44 0.25 5.00
167 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25 5.00
168 INT335028 Fgf15 Positive_regulation of Fgfr4 1 0.40 0.31 0.25 5.00
169 INT343914 Hmgb1 Positive_regulation of Gene_expression of IL12A 1 0.01 0.41 0.24 5.00
170 INT343906 Hmgb1 Positive_regulation of Gene_expression of Cd40 1 0.05 0.41 0.24 5.00
171 INT252784 ROS1 Positive_regulation of Gene_expression of COL1A1 1 0.05 1.86 0.24 5.00
172 INT335015 Fgf15 Negative_regulation of Gene_expression of Cyp7a1 1 0.57 0.2 0.24 5.00
173 INT343911 Mthfd1 Positive_regulation of Gene_expression of IL12A 1 0.00 0.41 0.23 5.00
174 INT252777 ROS1 Positive_regulation of Gene_expression of CCL2 1 0.31 0.77 0.23 5.00
175 INT298785 PPARA Positive_regulation of ACOX1 3 0.29 1.58 0.23 5.00
176 INT288732 Got1 Positive_regulation of Gene_expression of Gpt 1 0.31 0.52 0.23 5.00
177 INT250553 Binding of RS1 and SUGT1 3 0.00 3.36 0.22 5.00
178 INT343910 TLR4 Regulation of Gene_expression of Icam1 1 0.04 1.3 0.22 5.00
179 INT335025 Gm7647 Positive_regulation of Gene_expression of Fgf21 1 0.01 0.29 0.21 5.00
180 INT343849 Binding of FAS and TLR4 1 0.04 0.32 0.21 5.00
181 INT189321 Binding of Apoa1 and Hdlcl1 1 0.00 0.68 0.2 5.00
182 INT348032 Fndc3b Positive_regulation of Tlr2 1 0.01 1.3 0.2 5.00
183 INT348027 Gramd3 Negative_regulation of Irf3 1 0.00 1.39 0.2 5.00
184 INT348014 Binding of Tbk1 and Gramd3 1 0.00 1.33 0.2 5.00
185 INT348041 Binding of IFNA1 and Irf3 1 0.02 1.41 0.2 5.00
186 INT252787 Binding of FCGR3B and ROS1 1 0.06 0.58 0.2 5.00
187 INT348013 Negative_regulation of Binding of Irf3 and Tbk1 1 0.21 1.41 0.2 5.00
188 INT252814 ELANE Positive_regulation of Positive_regulation of CCL2 1 0.05 0.8 0.2 5.00
189 INT252782 ROS1 Positive_regulation of Positive_regulation of CCL2 1 0.22 0.8 0.2 5.00
190 INT343837 TICAM1 Positive_regulation of IRF3 1 0.03 0.19 0.19 5.00
191 INT343831 TICAM1 Positive_regulation of Gene_expression of TLR4 1 0.11 0.19 0.19 5.00
192 INT343827 MIRLET7I Regulation of Gene_expression of TLR4 1 0.00 0.13 0.19 5.00
193 INT343841 ZBP1 Regulation of Transcription of IFN1@ 1 0.00 0.2 0.19 5.00
194 INT316203 Ghsr Positive_regulation of Transcription of Agrp 1 0.02 1.5 0.19 5.00
195 INT335053 PPARA Positive_regulation of Gene_expression of LPL 1 0.21 0.34 0.19 5.00
196 INT343854 TIRAP Positive_regulation of IRF3 1 0.06 0.19 0.19 5.00
197 INT335046 PPARA Positive_regulation of Gene_expression of ABCA1 1 0.33 0.25 0.18 5.00
198 INT335018 Vdr Positive_regulation of Gene_expression of Fgf23 1 0.44 0.36 0.17 5.00
199 INT343852 Binding of TRAF1 and TICAM1 1 0.03 0.19 0.17 5.00
200 INT335131 PPARA Negative_regulation of Gene_expression of Fgg 1 0.01 0.59 0.17 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Fatty Liver. They are ordered first by their pain relevance and then by number of times they were reported in Fatty Liver. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT227337 Gene_expression of NAFLD2 7 0.05 10.98 0.83 100.00
2 INT252721 Binding of NAFLD2 3 0.03 5.36 0.23 100.00
3 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 100.00
4 INT199226 Positive_regulation of SAMSN1 6 0.57 10.2 0.9 100.00
5 INT250645 Gene_expression of Samsn1 6 0.33 9.95 0.86 100.00
6 INT117031 Binding of Samsn1 6 0.21 6.82 0.76 100.00
7 INT199224 Negative_regulation of Positive_regulation of SAMSN1 3 0.48 4.77 0.25 100.00
8 INT252705 Positive_regulation of NAFLD2 2 0.04 2.56 0.14 100.00
9 INT157416 Positive_regulation of Samsn1 6 0.53 4.28 0.33 100.00
10 INT252714 Negative_regulation of Gene_expression of NAFLD2 1 0.03 3.74 0.23 100.00
11 INT252707 Negative_regulation of Positive_regulation of NAFLD2 1 0.03 1.54 0.14 100.00
12 INT93207 Negative_regulation of Cyp4a3 11 0.36 4.32 2.63 100.00
13 INT229284 Positive_regulation of Pck1 6 0.43 1.24 0.35 100.00
14 INT226427 Gene_expression of FABP4 9 0.44 4.07 0.34 100.00
15 INT199222 Gene_expression of SAMSN1 14 0.57 18.97 1.61 99.98
16 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 99.96
17 INT152174 Negative_regulation of Samsn1 5 0.14 6.46 2.1 99.96
18 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 99.90
19 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 99.90
20 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 99.90
21 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 99.90
22 INT18583 Positive_regulation of Gene_expression of Ins1 67 0.50 49.72 8.26 99.90
23 INT89394 Phosphorylation of INS 37 0.82 35.84 3.9 99.88
24 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 99.84
25 INT197173 Positive_regulation of Cyp4a10 29 0.62 15.68 1.61 99.84
26 INT197174 Positive_regulation of Gene_expression of Cyp4a10 17 0.67 8.65 1.4 99.84
27 INT133876 Positive_regulation of Gene_expression of Ros1 141 0.32 75.55 27.45 99.84
28 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 99.84
29 INT314313 Gene_expression of Hmgcs1 1 0.06 0.77 0.08 99.84
30 INT53747 Positive_regulation of Cyp2e1 34 0.70 29.03 13.39 99.80
31 INT123284 Positive_regulation of Positive_regulation of Cyp2e1 3 0.46 2.34 1.22 99.80
32 INT28739 Binding of Ins1 35 0.37 22.43 2.14 99.76
33 INT318839 Binding of NUCKS1 2 0.13 0.84 0.18 99.72
34 INT162444 Positive_regulation of CYP4A11 4 0.43 4.11 0.61 99.68
35 INT26073 Gene_expression of Scd1 17 0.70 9.17 0.47 99.68
36 INT170734 Positive_regulation of Gene_expression of Scd1 5 0.48 5.87 0.13 99.68
37 INT187407 Negative_regulation of Gene_expression of Cd320 7 0.57 5.05 0.67 99.66
38 INT113149 Gene_expression of Tmprss11d 15 0.75 8.51 2.72 99.66
39 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 99.64
40 INT47859 Negative_regulation of Cyp2e1 41 0.59 16.92 21.72 99.58
41 INT240614 Gene_expression of Etv3 5 0.38 6.1 0.99 99.58
42 INT17808 Regulation of NTS 14 0.44 10.7 4.02 99.56
43 INT3206 Positive_regulation of Got1 39 0.69 19.36 17.02 99.56
44 INT2039 Regulation of CYP2B6 30 0.60 7.75 6.43 99.52
45 INT197166 Gene_expression of Cyp4a10 27 0.75 15.63 1.81 99.48
46 INT61116 Positive_regulation of Ppara 119 0.69 58.62 21.6 99.46
47 INT123464 Binding of ATP5G3 3 0.18 1.92 0.79 99.44
48 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76 99.34
49 INT301612 Negative_regulation of CYP4A11 1 0.36 1.15 0.07 99.32
50 INT256241 Positive_regulation of Gene_expression of Cd320 2 0.67 1.92 0 99.28
51 INT199221 Binding of SAMSN1 2 0.29 2.36 0.24 99.28
52 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 99.28
53 INT4003 Positive_regulation of Gene_expression of IGHG3 31 0.46 20.38 3.16 99.28
54 INT176181 Positive_regulation of Srebf1 10 0.42 3.69 0.62 99.28
55 INT10796 Gene_expression of CYP2B6 131 0.77 30.14 35.27 99.24
56 INT115374 Positive_regulation of Gene_expression of Cyp2e1 6 0.67 4.36 1.27 99.18
57 INT187411 Gene_expression of Cd320 23 0.75 12.1 1.39 99.10
58 INT179695 Negative_regulation of CYP4F3 4 0.45 4.94 1.38 99.08
59 INT189322 Binding of A2M 7 0.29 12.1 0.66 99.06
60 INT14572 Binding of INS 205 0.48 175.43 13.38 99.06
61 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46 99.00
62 INT227275 Negative_regulation of Gene_expression of Adipoq 19 0.53 19.51 1.15 99.00
63 INT62580 Gene_expression of Cyp2e1 31 0.78 15.4 11.08 98.98
64 INT190519 Positive_regulation of Positive_regulation of Ros1 14 0.32 9.99 1.52 98.98
65 INT280683 Gene_expression of Srebf1 12 0.44 6.31 0 98.72
66 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 98.72
67 INT304206 Positive_regulation of Gene_expression of Srebf1 1 0.34 0.61 0 98.72
68 INT301610 Negative_regulation of CYP4F2 1 0.39 0.83 0.08 98.68
69 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 98.64
70 INT14735 Positive_regulation of COL6A2 3 0.42 3.13 0.22 98.64
71 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33 98.60
72 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 98.60
73 INT190691 Negative_regulation of APOA1 12 0.42 15.9 0.39 98.56
74 INT280643 Negative_regulation of Gene_expression of Srebf1 4 0.32 1.01 0 98.56
75 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 98.48
76 INT236104 Positive_regulation of Negative_regulation of Ppara 6 0.59 6.91 0.91 98.48
77 INT352802 Regulation of FGF21 1 0.58 4.21 0 98.40
78 INT76924 Positive_regulation of Slc17a5 71 0.70 41.21 19.31 98.38
79 INT211562 Positive_regulation of Gene_expression of Lpin1 1 0.49 0.27 0 98.32
80 INT61599 Positive_regulation of CYP2C9 43 0.69 11.1 8.33 98.16
81 INT104290 Gene_expression of Ucp2 21 0.78 12.81 2.34 98.08
82 INT41791 Positive_regulation of NTS 12 0.49 5.69 4.15 98.08
83 INT104289 Positive_regulation of Gene_expression of Ucp2 7 0.59 4.46 1.13 98.08
84 INT334998 Positive_regulation of Fgf21 1 0.66 4.8 0.14 98.00
85 INT228685 Negative_regulation of Gene_expression of SCD 2 0.26 1.64 0.38 98.00
86 INT170743 Negative_regulation of Gene_expression of Scd1 2 0.38 1.57 0 98.00
87 INT3851 Gene_expression of Got1 58 0.65 29.15 10.52 97.92
88 INT105162 Gene_expression of Ad 47 0.12 46.53 1.83 97.92
89 INT301587 Negative_regulation of Batf 1 0.01 0.87 0.04 97.88
90 INT17686 Negative_regulation of Hdl1 72 0.36 81.85 7.74 97.76
91 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53 97.76
92 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58 97.68
93 INT22863 Negative_regulation of Apoa1 10 0.57 10.68 1.86 97.60
94 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 97.54
95 INT211548 Gene_expression of Lpin1 9 0.76 12.83 0.96 97.52
96 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 97.48
97 INT280659 Negative_regulation of Srebf1 4 0.32 1.83 0 97.12
98 INT3915 Gene_expression of SCD 25 0.57 13.94 6 97.08
99 INT320184 Binding of Fibp 1 0.02 1.69 0.11 96.96
100 INT28539 Binding of Etv3 7 0.21 3.83 0.74 96.96
101 INT252758 Positive_regulation of Protein_catabolism of APOB 1 0.01 0.98 0.03 96.94
102 INT345424 Phosphorylation of PAH 1 0.05 1.55 0.11 96.84
103 INT17562 Negative_regulation of Lipg 32 0.51 16.91 3.17 96.78
104 INT252743 Protein_catabolism of APOB 1 0.01 1.68 0.03 96.76
105 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 96.56
106 INT162443 Positive_regulation of Gene_expression of CYP4A11 2 0.31 0.86 0.33 96.56
107 INT334980 Negative_regulation of Fgf21 1 0.41 2.31 0.03 96.48
108 INT9904 Gene_expression of CYP2E1 64 0.78 13.11 14.65 96.48
109 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 96.40
110 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 96.28
111 INT217636 Regulation of fa 3 0.05 1.2 0.08 96.20
112 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14 96.12
113 INT77620 Gene_expression of Fas 146 0.78 72.4 16.61 96.00
114 INT62166 Positive_regulation of Gene_expression of Gpt 64 0.50 39.13 9.69 96.00
115 INT143645 Gene_expression of Fasn 4 0.42 2.32 0.4 96.00
116 INT256511 Binding of Fabp4 3 0.22 0.4 0.03 95.92
117 INT56292 Negative_regulation of Gene_expression of Ros1 70 0.38 36.14 9.17 95.60
118 INT74250 Negative_regulation of Gene_expression of Ins1 47 0.40 39.27 5.37 95.58
119 INT78676 Binding of Dbi 3 0.37 2.82 1.8 95.56
120 INT187422 Negative_regulation of MTTP 23 0.57 11.75 0.24 95.44
121 INT3217 Regulation of Ins1 154 0.62 87.11 27.29 95.36
122 INT87863 Positive_regulation of IL18 40 0.69 34.08 9.53 95.32
123 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36 95.28
124 INT67655 Regulation of Gene_expression of CYP4A11 2 0.28 0.77 0.99 95.20
125 INT43415 Gene_expression of CYP4A11 11 0.56 7.65 5.94 95.20
126 INT252725 Gene_expression of ABCD1 1 0.07 3.29 0.31 95.08
127 INT82722 Negative_regulation of Positive_regulation of Cyp2e1 6 0.59 3.74 2.02 95.04
128 INT252735 Negative_regulation of NRF1 1 0.19 1.59 0.08 95.04
129 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15 94.92
130 INT103094 Binding of PPARA 308 0.47 177.26 34.75 94.80
131 INT9865 Negative_regulation of Cyb5 5 0.34 1.52 2.23 94.80
132 INT173180 Positive_regulation of Binding of PPARA 14 0.49 3.66 1.88 94.80
133 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 94.34
134 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 94.28
135 INT57922 Gene_expression of CYP2C9 65 0.78 22.24 7.53 94.24
136 INT74164 Negative_regulation of UBXN11 14 0.42 6.76 1.4 94.16
137 INT151586 Positive_regulation of Prkag1 51 0.54 18.7 3.34 94.16
138 INT301530 Positive_regulation of Gene_expression of Cyp4a14 5 0.49 2.02 0.58 94.08
139 INT281180 Gene_expression of Cyp4a14 5 0.75 1.48 0.46 94.08
140 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49 93.92
141 INT35567 Negative_regulation of GGT5 4 0.09 1.77 0.47 93.76
142 INT145447 Positive_regulation of Transcription of Abcc1 1 0.24 1.85 2 93.68
143 INT120286 Positive_regulation of Abcc2 11 0.70 4.71 6.2 93.68
144 INT78914 Positive_regulation of ABCC1 19 0.67 7.99 5.18 93.68
145 INT89234 Positive_regulation of Gene_expression of Abcc1 10 0.50 3.56 2.66 93.68
146 INT143526 Positive_regulation of Abcc1 3 0.46 0.93 1.62 93.68
147 INT145443 Positive_regulation of Positive_regulation of Abcc2 1 0.07 0.93 1.06 93.68
148 INT145448 Positive_regulation of Transcription of Abcc4 1 0.35 0.93 1.01 93.68
149 INT145441 Positive_regulation of Gene_expression of Abcc4 1 0.35 0.93 1.01 93.68
150 INT145444 Positive_regulation of Abcc4 1 0.33 0.93 1.01 93.68
151 INT699 Positive_regulation of A2M 16 0.66 10.49 2.5 93.56
152 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 93.44
153 INT227273 Localization of Adipoq 22 0.72 18.04 1.72 93.36
154 INT25451 Negative_regulation of Gfm1 13 0.27 8.22 1.06 93.28
155 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33 93.12
156 INT19393 Gene_expression of Gfm1 31 0.51 18.9 3.2 93.08
157 INT334999 Regulation of Fgf21 1 0.43 2.33 0.09 93.08
158 INT182667 Binding of DLAT 11 0.31 40.75 2.8 93.08
159 INT145446 Transcription of Abcc1 3 0.64 1.83 1.99 92.96
160 INT122419 Transcription of ABCC1 10 0.70 4.45 4.61 92.96
161 INT145442 Transcription of Abcc4 1 0.51 0.92 1 92.96
162 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 92.92
163 INT7909 Positive_regulation of Positive_regulation of Got1 8 0.49 6.44 3.06 92.92
164 INT22491 Binding of Atrn 23 0.30 4.51 7.79 92.88
165 INT101105 Positive_regulation of FUT1 62 0.30 55.96 9.28 92.88
166 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 92.76
167 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 92.76
168 INT197171 Negative_regulation of Binding of Ppara 15 0.43 11.51 4.41 92.56
169 INT122041 Binding of Ppara 308 0.48 189.17 51.48 92.56
170 INT77281 Negative_regulation of HIVEP1 132 0.49 102.78 5.36 92.56
171 INT4238 Negative_regulation of ALPI 7 0.58 3.31 0.62 92.56
172 INT226780 Positive_regulation of Gene_expression of Retn 1 0.36 1.63 0.24 92.56
173 INT226783 Gene_expression of Retn 1 0.40 1.63 0.24 92.56
174 INT34584 Positive_regulation of Trglyd 3 0.05 2.96 0.16 92.48
175 INT812 Localization of INS 1026 0.81 515.6 145.31 92.32
176 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 92.28
177 INT89233 Gene_expression of Abcc1 21 0.77 9.2 4.36 92.28
178 INT145445 Gene_expression of Abcc4 1 0.48 0.91 1 92.28
179 INT190693 Negative_regulation of Regulation of APOA1 1 0.09 1.94 0.11 92.24
180 INT7083 Positive_regulation of HBM 35 0.66 20.96 4.3 92.16
181 INT28564 Negative_regulation of tp 4 0.37 1.91 1.29 92.08
182 INT307203 Transcription of Scd1 2 0.32 1.11 0 92.04
183 INT102175 Transcription of FASN 2 0.41 1.15 0.07 92.04
184 INT339772 Transcription of ACACA 1 0.16 0.55 0 92.04
185 INT23352 Negative_regulation of A2M 10 0.33 8.35 2.16 92.00
186 INT55671 Gene_expression of Ik 151 0.27 80.1 48.49 91.96
187 INT22943 Positive_regulation of Positive_regulation of Gpt 23 0.47 16.09 5.55 91.88
188 INT52088 Binding of Cyp2e1 8 0.48 2.5 4.43 91.80
189 INT301525 Positive_regulation of Cyp4a14 1 0.55 0.86 0.03 91.76
190 INT188584 Positive_regulation of Positive_regulation of TLR4 8 0.65 5.98 1.64 91.76
191 INT165468 Localization of fa 3 0.14 1.24 0.38 91.68
192 INT127900 Phosphorylation of EIF2AK3 14 0.80 7.99 1.22 91.40
193 INT109929 Phosphorylation of MAPK8 102 0.81 39.98 16.54 91.40
194 INT252712 Phosphorylation of TRAF2 1 0.28 1.38 0 91.40
195 INT252752 Phosphorylation of MTIF2 1 0.06 1.38 0 91.40
196 INT128973 Binding of Cyp4a10 3 0.38 2.14 0.28 91.28
197 INT301604 Positive_regulation of Positive_regulation of FFAR1 1 0.01 0.74 0.03 91.28
198 INT16608 Positive_regulation of FFAR1 40 0.37 18.48 3.59 91.28
199 INT163994 Positive_regulation of Binding of Cyp2e1 2 0.50 0.45 0.5 91.28
200 INT301527 Binding of Cyp4a12a 1 0.17 0.17 0 91.28
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