D:Febrile Convulsions

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Disease Term
Synonyms Convulsion Febrile, Convulsion Fever, Convulsion Pyrexial, Convulsions Febrile, CONVULSIONS FEVER, Convulsions Pyrexial, Febrile Convulsion, Febrile Convulsion Seizure, FEBRILE CONVULSION SEIZURES, Febrile Fit, Febrile Fits
Documents 96
Hot Single Events 35
Hot Interactions 3

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Febrile Convulsions. They are ordered first by their relevance to Febrile Convulsions and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT279828 Binding of Scn1a and Scn9a 1 0.39 1.64 0.26 100.00
2 INT279829 Scn1a Regulation of Gene_expression of Scn9a 1 0.42 1.52 0.15 100.00
3 INT341336 Binding of Pepd and Nav1 1 0.07 0.92 1.3 99.84
4 INT174699 Binding of Tlr2 and Tlr3 3 0.14 0.66 0.35 48.32
5 INT337072 Binding of Fmr1 and Gusb 1 0.19 1.55 0.08 5.00
6 INT338457 Binding of IGHV3-63 and C5orf43 1 0.00 1.05 0 5.00
7 INT338456 Binding of ZNF76 and IGHV3-63 1 0.00 1.04 0 5.00
8 INT314986 Ins1 Negative_regulation of CACNA1S 1 0.00 0.08 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Febrile Convulsions. They are ordered first by their pain relevance and then by number of times they were reported in Febrile Convulsions. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT70738 Negative_regulation of Gabrg2 7 0.57 4 2.96 100.00
2 INT279826 Negative_regulation of Scn1b 1 0.35 1.31 0.04 100.00
3 INT279820 Negative_regulation of Scn2a1 1 0.35 1.31 0.04 100.00
4 INT279816 Negative_regulation of Scn1a 1 0.40 1.31 0.04 100.00
5 INT243808 Positive_regulation of Transcription of Sh2b2 1 0.29 0.86 0.33 99.84
6 INT85767 Gene_expression of Scn9a 11 0.76 9.27 2.74 99.70
7 INT279821 Regulation of Scn9a 2 0.44 2.79 0.83 98.96
8 INT116321 Regulation of Nav1 38 0.62 26.62 37.97 98.96
9 INT243807 Transcription of Sh2b2 1 0.39 0.85 0.33 98.84
10 INT279825 Negative_regulation of Scn9a 1 0.37 0.8 0.08 97.84
11 INT279823 Gene_expression of Pepd 1 0.19 2 1.14 97.08
12 INT260049 Negative_regulation of PCDH19 1 0.58 4.41 0.04 96.76
13 INT260050 Gene_expression of PCDH19 1 0.77 12.52 0.09 96.48
14 INT282807 Localization of MECP2 1 0.73 1.18 0.06 96.24
15 INT19948 Gene_expression of Sds 34 0.63 14.69 15.44 95.72
16 INT111051 Negative_regulation of Nav1 64 0.59 25.51 47.27 94.68
17 INT113384 Regulation of Gene_expression of Nav1 20 0.62 8.57 16.15 93.96
18 INT94450 Gene_expression of Nav1 359 0.78 131.85 275.46 92.84
19 INT157927 Gene_expression of Scn1a 5 0.64 6.55 2.02 92.80
20 INT89834 Positive_regulation of SCN2A 8 0.49 1.89 2.77 92.64
21 INT279822 Gene_expression of Scn2a1 2 0.65 1.73 1.85 92.52
22 INT279814 Gene_expression of Scn3a 1 0.50 1.63 0.05 92.12
23 INT279817 Regulation of Gm4425 1 0.00 1.18 0.45 91.76
24 INT103882 Gene_expression of MECP2 17 0.76 10.47 0.96 91.04
25 INT148658 Negative_regulation of Csnk1a1 2 0.08 0.99 0.75 89.96
26 INT148660 Negative_regulation of Ppp3ca 1 0.02 0.59 0.67 89.96
27 INT74486 Positive_regulation of SCN1A 4 0.67 1 2.2 86.76
28 INT148659 Positive_regulation of Scn3a 1 0.06 0.64 0.67 86.76
29 INT148661 Positive_regulation of LAMB1 2 0.05 0.64 0.67 86.76
30 INT98068 Gene_expression of SCN2A 19 0.75 14.42 3.31 86.04
31 INT259867 Binding of SCN1A 2 0.36 4.7 0.21 83.92
32 INT183753 Regulation of HBM 24 0.39 13.13 1.79 81.84
33 INT103261 Positive_regulation of Nav1 68 0.70 24.25 39.27 81.44
34 INT72252 Gene_expression of Kcnma1 63 0.64 20.47 29.56 81.40
35 INT71593 Gene_expression of Mpv17l 9 0.04 1.68 4.01 80.08
36 INT14031 Gene_expression of Npy 107 0.78 36.48 35.4 78.56
37 INT21794 Positive_regulation of Gene_expression of Npy 20 0.70 8.44 9.3 78.56
38 INT98376 Gene_expression of tk 27 0.51 21.9 2.23 76.44
39 INT199566 Positive_regulation of Gene_expression of tk 4 0.39 3.06 0.31 76.44
40 INT279815 Positive_regulation of Gene_expression of Scn9a 1 0.43 0.67 0.03 76.44
41 INT260734 Gene_expression of Acin1 2 0.16 1 0.03 76.44
42 INT279819 Positive_regulation of Gene_expression of Acin1 1 0.12 0.67 0.03 76.44
43 INT35742 Positive_regulation of tk 8 0.43 5.53 1.33 70.76
44 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 70.56
45 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 70.56
46 INT38564 Binding of AIS 36 0.38 27.77 9.31 69.28
47 INT279824 Positive_regulation of Scn1a 1 0.47 1.22 0 68.96
48 INT260046 Gene_expression of PCDH11Y 1 0.48 0.62 0 68.64
49 INT12031 Negative_regulation of Car1 44 0.59 20.46 19.36 68.52
50 INT169864 Positive_regulation of Gene_expression of SCN2A 1 0.45 0.38 0 68.16
51 INT54370 Negative_regulation of VTA1 5 0.50 2.06 2.77 62.08
52 INT67737 Negative_regulation of Pam 6 0.51 4.08 2.19 62.08
53 INT314985 Positive_regulation of Negative_regulation of Pam 1 0.05 2.1 0.15 62.08
54 INT149985 Gene_expression of Tlr9 32 0.75 29.83 11.86 60.72
55 INT174682 Gene_expression of Tlr8 1 0.39 1.47 0.22 60.00
56 INT174689 Gene_expression of Tlr7 11 0.67 8.24 1.56 59.52
57 INT174684 Gene_expression of Tlr6 2 0.44 2.62 0.36 59.04
58 INT174686 Gene_expression of Tlr5 1 0.24 1.34 0.26 58.56
59 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 58.08
60 INT158595 Gene_expression of Tlr3 25 0.69 12.09 4.07 57.60
61 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26 57.12
62 INT103262 Localization of Nav1 53 0.81 19.23 34.44 56.96
63 INT80319 Negative_regulation of Negative_regulation of Car1 3 0.59 2 2.58 56.24
64 INT1317 Negative_regulation of Sds 23 0.48 6.97 5.03 55.32
65 INT189077 Gene_expression of PEA15 3 0.28 0.71 0.05 54.48
66 INT111053 Positive_regulation of Positive_regulation of Nav1 4 0.46 2.97 3.53 52.88
67 INT140224 Localization of Ccl2 32 0.72 26.91 9.39 52.64
68 INT96269 Positive_regulation of Mcpt1 71 0.61 52.38 20.4 51.44
69 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58 51.44
70 INT61495 Positive_regulation of ICA1 8 0.49 4.19 3.87 50.00
71 INT130332 Gene_expression of Adam17 14 0.50 4.84 1.56 50.00
72 INT279818 Gene_expression of Gm4425 1 0.01 0.77 0.47 50.00
73 INT74485 Positive_regulation of Scn9a 2 0.49 0.81 0.19 50.00
74 INT158596 Binding of Tlr3 24 0.47 11.66 3.69 49.52
75 INT251958 Gene_expression of VTA1 9 0.58 7.26 5.6 49.36
76 INT174688 Binding of Tlr2 45 0.42 36.65 5.25 43.52
77 INT174683 Transcription of Tlr2 12 0.58 5.95 1.4 42.24
78 INT54369 Regulation of VTA1 4 0.38 3.03 3.18 37.92
79 INT174687 Regulation of Positive_regulation of Il6 10 0.61 9.07 2.61 12.20
80 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 11.56
81 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
82 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75 5.00
83 INT97367 Gene_expression of Nav1 243 0.78 132.97 286.66 5.00
84 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
85 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 5.00
86 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 5.00
87 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 5.00
88 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
89 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
90 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
91 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
92 INT100965 Positive_regulation of Nav1 85 0.70 37.74 75.35 5.00
93 INT55224 Gene_expression of DRGX 99 0.31 67.55 67.63 5.00
94 INT97368 Negative_regulation of Nav1 62 0.59 41.56 60.27 5.00
95 INT129303 Positive_regulation of NAV1 54 0.70 36.92 57.45 5.00
96 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24 5.00
97 INT131413 Positive_regulation of Gene_expression of NAV1 35 0.70 17.5 36.83 5.00
98 INT111052 Positive_regulation of Gene_expression of Nav1 44 0.70 18.98 35.28 5.00
99 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 5.00
100 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
101 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
102 INT102429 Negative_regulation of Gene_expression of Nav1 19 0.59 20.09 28.09 5.00
103 INT136268 Localization of NAV1 22 0.75 2.84 26.23 5.00
104 INT116226 Regulation of NAV1 20 0.51 14.32 25.61 5.00
105 INT256285 Gene_expression of Efnb1 32 0.70 36.25 24.73 5.00
106 INT141612 Gene_expression of Ccr1 92 0.77 72.09 24.14 5.00
107 INT145971 Localization of Nav1 20 0.81 10.3 18.11 5.00
108 INT111050 Negative_regulation of Gene_expression of Nav1 23 0.58 5.97 17.06 5.00
109 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 5.00
110 INT112207 Binding of Nav1 27 0.47 7.1 15.43 5.00
111 INT28314 Negative_regulation of Gene_expression of Gabrg1 29 0.44 12.56 13.8 5.00
112 INT148639 Gene_expression of Uchl1 30 0.59 16.76 11.54 5.00
113 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59 5.00
114 INT67048 Gene_expression of ITGA4 58 0.75 28.93 10.16 5.00
115 INT108384 Binding of Ntrk1 28 0.39 10.73 9.09 5.00
116 INT158796 Positive_regulation of SMUG1 67 0.70 38.97 8.98 5.00
117 INT148864 Localization of DRGX 11 0.17 7.67 8.36 5.00
118 INT54368 Positive_regulation of VTA1 13 0.59 3.81 8.13 5.00
119 INT162393 Gene_expression of SMUG1 58 0.75 38.78 7.7 5.00
120 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 5.00
121 INT28315 Regulation of Gene_expression of Gabrg1 20 0.60 4.78 7 5.00
122 INT28861 Binding of Gh 61 0.46 25.61 6.38 5.00
123 INT41892 Gene_expression of HBM 48 0.64 28.32 5.64 5.00
124 INT104391 Gene_expression of Tnpo1 12 0.65 9.61 4.87 5.00
125 INT7083 Positive_regulation of HBM 35 0.66 20.96 4.3 5.00
126 INT252968 Positive_regulation of TAF9 11 0.45 5.28 3.68 5.00
127 INT93308 Gene_expression of PIRT 13 0.09 2 2.92 5.00
128 INT47011 Positive_regulation of Gusb 14 0.44 8.93 2.87 5.00
129 INT25208 Gene_expression of IGF2 43 0.74 30.64 2.31 5.00
130 INT56375 Positive_regulation of AMBP 25 0.60 21.24 2.22 5.00
131 INT159645 Negative_regulation of Uchl1 8 0.31 6.84 2.14 5.00
132 INT151538 Positive_regulation of Fmr1 21 0.68 12.24 2.07 5.00
133 INT160814 Gene_expression of Il6ra 15 0.07 9.61 1.73 5.00
134 INT82918 Binding of AMBP 23 0.39 23.31 1.71 5.00
135 INT151543 Binding of Fmr1 56 0.48 19.4 1.65 5.00
136 INT214123 Negative_regulation of Gene_expression of Uchl1 3 0.06 4.52 1.52 5.00
137 INT153599 Gene_expression of SCN1A 8 0.75 7.01 1.47 5.00
138 INT113377 Positive_regulation of Localization of Nav1 2 0.70 0.23 1.46 5.00
139 INT65832 Positive_regulation of PIRT 4 0.07 0.83 1.42 5.00
140 INT45155 Negative_regulation of Polymerase 18 0.51 15.18 1.38 5.00
141 INT67133 Gene_expression of Gusb 14 0.75 18.57 1.37 5.00
142 INT304986 Regulation of Gene_expression of VTA1 1 0.38 1.87 1.24 5.00
143 INT115481 Gene_expression of CDSN 6 0.10 2.53 1.03 5.00
144 INT284844 Regulation of Localization of Nav1 2 0.59 0.18 0.83 5.00
145 INT246552 Transcription of Fmr1 11 0.72 6.72 0.71 5.00
146 INT70104 Positive_regulation of CACNA1S 6 0.47 5.92 0.68 5.00
147 INT180743 Binding of SARS 12 0.23 17.94 0.62 5.00
148 INT243712 Positive_regulation of Gene_expression of Uchl1 4 0.21 2.68 0.61 5.00
149 INT86624 Binding of Efnb1 4 0.27 1.09 0.6 5.00
150 INT173429 Phosphorylation of NAV1 1 0.61 0.05 0.57 5.00
151 INT180528 Positive_regulation of SARS 12 0.30 18.6 0.53 5.00
152 INT174685 Negative_regulation of Tnpo1 1 0.03 1.18 0.48 5.00
153 INT341334 Negative_regulation of Localization of Nav1 1 0.41 0.22 0.42 5.00
154 INT316899 Positive_regulation of Gene_expression of VTA1 2 0.45 2.67 0.32 5.00
155 INT260038 Localization of Efnb1 3 0.57 1.14 0.3 5.00
156 INT226826 Gene_expression of Scn1b 5 0.57 0.52 0.22 5.00
157 INT341335 Gene_expression of Scn2b 1 0.41 0 0.22 5.00
158 INT180736 Binding of Emid1 4 0.36 6.69 0.22 5.00
159 INT226598 Localization of PSMC1 1 0.21 0.33 0.22 5.00
160 INT226597 Regulation of Localization of DRGX 1 0.08 0.32 0.21 5.00
161 INT173428 Binding of Po 1 0.36 0 0.19 5.00
162 INT287577 Positive_regulation of Transcription of Fmr1 2 0.48 2.5 0.16 5.00
163 INT226596 Localization of DIS3L 1 0.05 0.26 0.12 5.00
164 INT314984 Positive_regulation of Cd2ap 1 0.01 0.75 0.11 5.00
165 INT237664 Negative_regulation of Gene_expression of SMUG1 1 0.02 0.39 0.1 5.00
166 INT180738 Regulation of SARS 7 0.23 7.75 0.1 5.00
167 INT151522 Binding of NSD1 2 0.37 4.28 0.09 5.00
168 INT214056 Negative_regulation of NSD1 3 0.43 3.44 0.09 5.00
169 INT212476 Binding of FNDC3A 1 0.03 0.06 0.07 5.00
170 INT338460 Binding of C5orf43 1 0.01 1.96 0.04 5.00
171 INT338461 Binding of IGHV3-63 1 0.01 1.97 0.04 5.00
172 INT338466 Binding of ZNF76 1 0.01 1.96 0.04 5.00
173 INT207781 Gene_expression of CACNA1S 3 0.63 0.9 0.03 5.00
174 INT347044 Negative_regulation of SIGLEC1 1 0.02 0.41 0.03 5.00
175 INT314979 Negative_regulation of Localization of Lp1 1 0.10 0.1 0 5.00
176 INT338464 Regulation of C5orf43 1 0.01 0.78 0 5.00
177 INT314978 Binding of Lp1 1 0.09 0.25 0 5.00
178 INT260048 Binding of PCDH19 1 0.37 4.77 0 5.00
179 INT260037 Positive_regulation of Binding of Efnb1 1 0.24 1.04 0 5.00
180 INT214055 Gene_expression of NSD1 8 0.67 4.46 0 5.00
181 INT314980 Localization of Lp1 1 0.18 0 0 5.00
182 INT338463 Regulation of ZNF76 1 0.00 0.78 0 5.00
183 INT260051 Positive_regulation of PCDH19 1 0.69 1.69 0 5.00
184 INT338462 Gene_expression of IGHV3-63 1 0.02 0.82 0 5.00
185 INT260047 Regulation of PCDH19 1 0.45 1.43 0 5.00
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