D:Fecal Incontinence

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Faecal Incontinence, Fecal Incontinences, Incontinence Fecal, Incontinences Fecal
Documents 335
Hot Single Events 15
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Fecal Incontinence. They are ordered first by their relevance to Fecal Incontinence and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT191984 Ide Positive_regulation of Nppc 1 0.04 0.13 0 34.12
2 INT326605 Binding of HTR1A and KCNH2 1 0.00 0.45 0.14 5.00
3 INT290877 Binding of Bcl2a1c and Lepr 1 0.00 0.87 0.04 5.00
4 INT191980 Ide Regulation of Sit1 1 0.17 0 0.04 5.00
5 INT170858 Binding of IFI27 and Ccne2 1 0.01 0.17 0 5.00
6 INT218240 Binding of SAE1 and Dync1h1 1 0.00 0.17 0 5.00
7 INT191982 Sit1 Regulation of Gene_expression of Ide 1 0.25 0.09 0 5.00
8 INT170841 Binding of CFD and IFI27 1 0.07 0.37 0 5.00
9 INT191981 Ide Positive_regulation of Positive_regulation of Sit1 1 0.28 0.06 0 5.00
10 INT353062 HSD11B1 Regulation of Gene_expression of ADIPOQ 1 0.13 5.03 0 5.00
11 INT290861 MNT Positive_regulation of INS 1 0.03 1.78 0 5.00
12 INT353061 HSD11B1 Regulation of Gene_expression of LEP 1 0.20 5.03 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Fecal Incontinence. They are ordered first by their pain relevance and then by number of times they were reported in Fecal Incontinence. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT2774 Binding of Crp 241 0.48 195.89 44.39 99.98
2 INT223061 Negative_regulation of RBT 1 0.24 0.64 0 98.76
3 INT223062 Regulation of RBT 1 0.25 1.21 0 98.20
4 INT49566 Positive_regulation of LMOD1 16 0.61 5.74 5.92 95.80
5 INT192951 Negative_regulation of AES 15 0.38 6.38 3.5 93.36
6 INT44136 Positive_regulation of MLN 8 0.69 1.77 1.42 92.44
7 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1 92.32
8 INT21687 Positive_regulation of ras 143 0.58 97.34 27.31 90.88
9 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98 89.44
10 INT169987 Transcription of GOPC 45 0.60 21.88 2.61 88.16
11 INT134482 Negative_regulation of MMVP1 1 0.00 0.98 0.09 88.04
12 INT287309 Positive_regulation of ENO1 5 0.59 5.67 1.52 87.72
13 INT286474 Localization of ITM2B 2 0.47 5.27 1.21 86.08
14 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 84.16
15 INT350364 Negative_regulation of ITM2B 1 0.27 10.5 3.42 82.60
16 INT80420 Gene_expression of IFI27 145 0.78 63.61 8.83 79.44
17 INT157892 Binding of PNLIP 5 0.25 4.58 0.65 76.88
18 INT36502 Positive_regulation of asp1 10 0.40 6.26 4.45 75.00
19 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51 75.00
20 INT168446 Gene_expression of Prep 25 0.64 15.17 5.94 72.40
21 INT223064 Binding of RBT 1 0.21 0.2 0 71.12
22 INT223063 Positive_regulation of Binding of 1 0.28 0.2 0 71.12
23 INT81688 Binding of ras 32 0.41 30.13 4.02 66.96
24 INT124322 Negative_regulation of PNLIP 11 0.31 6.53 1.88 64.40
25 INT28576 Binding of MLN 18 0.48 5.45 2.26 63.84
26 INT105332 Regulation of Gene_expression of IFI27 14 0.45 8.39 2.02 63.12
27 INT326607 Positive_regulation of STC1 1 0.20 3 0.2 61.32
28 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 59.88
29 INT108131 Localization of GRHL3 3 0.73 1.03 2.18 58.96
30 INT30868 Binding of Lrrc23 2 0.17 1.17 0.43 58.16
31 INT22388 Gene_expression of MLN 15 0.75 4.86 1.14 55.56
32 INT238013 Negative_regulation of Gene_expression of MLN 2 0.42 0.64 0.08 55.56
33 INT95794 Gene_expression of GRHL3 9 0.68 5.57 9.9 55.44
34 INT94408 Positive_regulation of Gene_expression of IFI27 28 0.65 12.89 3.53 50.96
35 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 50.40
36 INT3851 Gene_expression of Got1 58 0.65 29.15 10.52 49.04
37 INT8629 Positive_regulation of COL7A1 72 0.69 40.66 12.09 44.48
38 INT22781 Binding of COL7A1 76 0.48 41.59 6.66 43.36
39 INT191973 Gene_expression of Sit1 13 0.44 1.84 0.17 42.44
40 INT75932 Binding of Csf2 45 0.37 33.2 8.01 34.08
41 INT244367 Gene_expression of CENPI 1 0.07 0.2 0.11 28.48
42 INT191966 Regulation of Regulation of Sit1 1 0.15 0.14 0.03 28.24
43 INT103271 Regulation of Sit1 3 0.24 1.32 0.47 26.72
44 INT65642 Binding of Dync1h1 27 0.41 15.83 2.68 25.52
45 INT58602 Gene_expression of HMI 34 0.65 25.26 3.74 17.08
46 INT225060 Gene_expression of ITM2B 2 0.43 5.97 2.33 15.20
47 INT39919 Negative_regulation of MLN 9 0.36 2.91 1.06 5.76
48 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
49 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
50 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
51 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
52 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
53 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
54 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 5.00
55 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 5.00
56 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 5.00
57 INT251 Regulation of INS 398 0.62 232.47 55.04 5.00
58 INT62630 Positive_regulation of CNR1 86 0.70 40.34 51.51 5.00
59 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 5.00
60 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 5.00
61 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 5.00
62 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
63 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 5.00
64 INT23330 Binding of Chrna7 79 0.48 10.06 35.5 5.00
65 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
66 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 5.00
67 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
68 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 5.00
69 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 5.00
70 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22 5.00
71 INT10442 Negative_regulation of CNR1 47 0.59 20.88 20.2 5.00
72 INT20305 Gene_expression of Cyp2e1 53 0.78 19.75 19.54 5.00
73 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 5.00
74 INT68347 Negative_regulation of Cyp2d4 34 0.58 7.62 18.35 5.00
75 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92 5.00
76 INT145097 Negative_regulation of Pain1 16 0.22 19.11 16.82 5.00
77 INT6381 Negative_regulation of Chat 51 0.59 19.68 15.86 5.00
78 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
79 INT75908 Regulation of LEP 77 0.60 60.16 15.19 5.00
80 INT7776 Gene_expression of Abcb1b 63 0.75 21.35 14.92 5.00
81 INT18773 Localization of ALB 117 0.80 69.18 13.8 5.00
82 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 5.00
83 INT14572 Binding of INS 205 0.48 175.43 13.38 5.00
84 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 5.00
85 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 5.00
86 INT56494 Localization of Ide 73 0.68 22.9 11.26 5.00
87 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17 5.00
88 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 5.00
89 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47 5.00
90 INT57665 Negative_regulation of Cyp2e1 35 0.59 8.05 9.29 5.00
91 INT107087 Positive_regulation of Gene_expression of Cyp2e1 20 0.70 8.89 9.04 5.00
92 INT59165 Binding of fc 67 0.36 37.51 8.68 5.00
93 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 5.00
94 INT79168 Binding of TNC 39 0.47 16.51 7.55 5.00
95 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53 5.00
96 INT102572 Gene_expression of Ccnd1 79 0.69 56.37 7.34 5.00
97 INT31333 Gene_expression of Esr2 19 0.69 8.78 6.83 5.00
98 INT539 Negative_regulation of Chrna7 14 0.42 4.59 6.42 5.00
99 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2 5.00
100 INT17913 Regulation of HSD11B1 87 0.60 93.23 6.04 5.00
101 INT120335 Gene_expression of SNAP25 24 0.65 9.44 5.83 5.00
102 INT12183 Negative_regulation of Cyp2d1 11 0.58 3.11 5.49 5.00
103 INT65356 Localization of LEP 46 0.79 41.17 5.43 5.00
104 INT23952 Gene_expression of Cyp2d4 18 0.78 4.76 5.31 5.00
105 INT81796 Binding of AGRP 62 0.36 37.19 5.3 5.00
106 INT75682 Regulation of Chrna7 14 0.45 10.24 5.25 5.00
107 INT58060 Negative_regulation of HMI 30 0.44 11.9 5.06 5.00
108 INT56495 Positive_regulation of Localization of Ide 20 0.53 3.53 4.92 5.00
109 INT170854 Gene_expression of CFD 26 0.68 39.77 4.74 5.00
110 INT60957 Negative_regulation of Abcb1b 18 0.57 6 4.73 5.00
111 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 5.00
112 INT170604 Negative_regulation of Gene_expression of GOPC 50 0.35 12.71 4.51 5.00
113 INT72703 Gene_expression of Ide 79 0.70 45.04 4.47 5.00
114 INT80421 Positive_regulation of IFI27 26 0.65 15.32 3.93 5.00
115 INT4649 Positive_regulation of Chrna7 17 0.50 5.48 3.92 5.00
116 INT33008 Gene_expression of Dync1h1 41 0.68 23.85 3.82 5.00
117 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67 5.00
118 INT84005 Negative_regulation of Positive_regulation of CNR1 7 0.41 3.55 3.66 5.00
119 INT55516 Gene_expression of Cyp2d1 5 0.60 0.83 3.58 5.00
120 INT58643 Positive_regulation of HMI 10 0.50 6.59 3.5 5.00
121 INT43085 Negative_regulation of Ide 28 0.39 19.96 3.45 5.00
122 INT16969 Negative_regulation of CRS 28 0.37 14.77 3.35 5.00
123 INT202577 Localization of DIO2 9 0.56 1.3 2.97 5.00
124 INT161812 Positive_regulation of PER1 17 0.56 5.64 2.93 5.00
125 INT85885 Positive_regulation of SNAP25 8 0.69 2.74 2.84 5.00
126 INT134795 Positive_regulation of Scrib 30 0.22 36.91 2.81 5.00
127 INT103020 Gene_expression of SGCA 22 0.56 14.29 2.75 5.00
128 INT145328 Negative_regulation of Scrib 25 0.16 26.79 2.66 5.00
129 INT97443 Positive_regulation of Positive_regulation of LEP 13 0.50 11.91 2.65 5.00
130 INT93207 Negative_regulation of Cyp4a3 11 0.36 4.32 2.63 5.00
131 INT191974 Regulation of Ide 16 0.38 9.54 2.52 5.00
132 INT287307 Binding of ENO1 9 0.48 11.24 2.51 5.00
133 INT111451 Regulation of ADIPOQ 24 0.56 18.81 2.47 5.00
134 INT16964 Binding of IFNG 27 0.48 14.31 2.45 5.00
135 INT183668 Binding of SGCA 15 0.36 9.86 2.42 5.00
136 INT74446 Positive_regulation of Dync1h1 25 0.59 13 2.38 5.00
137 INT152060 Gene_expression of VUR 75 0.67 83.83 2.34 5.00
138 INT61340 Regulation of Prep 7 0.50 6.13 2.31 5.00
139 INT142626 Negative_regulation of Localization of ALB 9 0.55 6.63 2.24 5.00
140 INT17934 Localization of MLN 16 0.80 2.83 2.24 5.00
141 INT93764 Binding of GRHL3 3 0.36 1.79 2.07 5.00
142 INT106607 Protein_catabolism of IFI27 6 0.93 1.76 2.01 5.00
143 INT191534 Negative_regulation of EGFL7 10 0.06 7.52 1.98 5.00
144 INT98782 Gene_expression of Cdkn1b 70 0.75 36.43 1.9 5.00
145 INT47425 Localization of Chrna7 11 0.81 6.7 1.86 5.00
146 INT169387 Regulation of Gene_expression of Chrna7 4 0.36 2.19 1.63 5.00
147 INT29566 Positive_regulation of Bpifa2 22 0.46 8.04 1.62 5.00
148 INT167847 Positive_regulation of Gene_expression of Chrna7 7 0.49 3.02 1.57 5.00
149 INT41986 Positive_regulation of Gene_expression of HSD11B1 26 0.49 32.84 1.52 5.00
150 INT93350 Binding of Lepr 17 0.05 27.21 1.5 5.00
151 INT188241 Negative_regulation of ADIPOQ 16 0.43 22.16 1.47 5.00
152 INT170853 Positive_regulation of Gene_expression of CFD 7 0.23 9.89 1.41 5.00
153 INT191970 Positive_regulation of Ide 29 0.51 12.94 1.4 5.00
154 INT227424 Binding of Prep 6 0.35 2.61 1.39 5.00
155 INT108325 Gene_expression of Scrib 26 0.39 48.33 1.39 5.00
156 INT199004 Gene_expression of ARMC9 43 0.58 17.72 1.32 5.00
157 INT140394 Regulation of Dync1h1 7 0.39 2.59 1.25 5.00
158 INT287308 Negative_regulation of ENO1 5 0.59 4.07 1.24 5.00
159 INT213277 Positive_regulation of Gene_expression of ADIPOQ 14 0.50 17.7 1.14 5.00
160 INT68565 Gene_expression of Fap 14 0.57 24.39 1.14 5.00
161 INT79780 Gene_expression of Cyp4a3 14 0.56 5.19 1.12 5.00
162 INT22095 Negative_regulation of Dync1h1 11 0.48 5.17 1.08 5.00
163 INT79928 Positive_regulation of Localization of ALB 10 0.60 8.96 1.05 5.00
164 INT197721 Positive_regulation of ARMC9 36 0.35 20.08 1.03 5.00
165 INT122285 Gene_expression of Cog1 10 0.14 5.95 0.98 5.00
166 INT17817 Binding of VUR 41 0.48 46.85 0.95 5.00
167 INT4681 Localization of RAPGEF5 12 0.68 8.69 0.93 5.00
168 INT56200 Negative_regulation of Negative_regulation of Chat 3 0.25 1.38 0.88 5.00
169 INT170813 Gene_expression of Prdm6 11 0.65 4.35 0.88 5.00
170 INT72715 Positive_regulation of Nppc 4 0.39 1.55 0.87 5.00
171 INT46298 Regulation of Ankrd23 3 0.27 1.31 0.86 5.00
172 INT148271 Regulation of SGCA 10 0.37 5.89 0.86 5.00
173 INT191926 Negative_regulation of Lepr 13 0.48 17.68 0.8 5.00
174 INT124850 Gene_expression of Tpt1 42 0.77 14.51 0.79 5.00
175 INT80122 Gene_expression of ESRRB 4 0.41 2.21 0.78 5.00
176 INT106621 Negative_regulation of Protein_catabolism of IFI27 3 0.40 0.49 0.76 5.00
177 INT39562 Negative_regulation of Sit1 4 0.42 1.92 0.72 5.00
178 INT140637 Negative_regulation of IFI27 11 0.40 9.48 0.69 5.00
179 INT149928 Positive_regulation of Negative_regulation of Cyp2e1 2 0.50 0.35 0.68 5.00
180 INT125635 Negative_regulation of Cyp2c6 3 0.59 0.18 0.66 5.00
181 INT106613 Regulation of IFI27 6 0.57 3.12 0.66 5.00
182 INT191978 Positive_regulation of Gene_expression of Ide 16 0.63 6.8 0.65 5.00
183 INT4783 Localization of GHRL 5 0.11 1.28 0.61 5.00
184 INT69486 Negative_regulation of Bcl2a1c 34 0.10 19.03 0.6 5.00
185 INT105238 Negative_regulation of PRSS3P2 2 0.19 1.26 0.51 5.00
186 INT176646 Binding of Bpifa2 15 0.30 7.65 0.5 5.00
187 INT47030 Negative_regulation of ARMC9 22 0.38 13.08 0.47 5.00
188 INT191968 Negative_regulation of Gene_expression of Ide 9 0.39 7.14 0.47 5.00
189 INT185152 Positive_regulation of T2dm2 7 0.17 14.93 0.46 5.00
190 INT161749 Regulation of VUR 9 0.39 9.3 0.46 5.00
191 INT165620 Negative_regulation of Gene_expression of HSD11B1 10 0.41 14.52 0.45 5.00
192 INT48418 Localization of Dync1h1 4 0.61 1.54 0.44 5.00
193 INT212271 Binding of ARMC9 14 0.27 3.29 0.43 5.00
194 INT11118 Gene_expression of RAPGEF5 13 0.65 9.35 0.43 5.00
195 INT109703 Positive_regulation of Sit1 10 0.41 1.83 0.43 5.00
196 INT72717 Gene_expression of Nppc 8 0.51 6.25 0.39 5.00
197 INT117313 Negative_regulation of VUR 11 0.42 12.14 0.39 5.00
198 INT171210 Negative_regulation of Ibdq1 1 0.02 1.71 0.36 5.00
199 INT61236 Gene_expression of Cyp2c6 3 0.78 1.55 0.35 5.00
200 INT218235 Negative_regulation of Gene_expression of Dync1h1 2 0.37 0.57 0.34 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox