D:Femoral Neck Fractures

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Disease Term
Synonyms Femoral Neck Fracture, FEMUR NECK FRACTURE, FEMUR NECK FRACTURES
Documents 347
Hot Single Events 13
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Femoral Neck Fractures. They are ordered first by their relevance to Femoral Neck Fractures and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT342382 Binding of Car1 and Lrp5 1 0.40 0.9 0 98.80
2 INT342387 Binding of CALCR and Car1 1 0.11 0.83 0 56.48
3 INT342388 Binding of CALCR and Vdr 1 0.12 0.83 0 56.48
4 INT342379 Binding of Car1 and Sugt1 1 0.01 0.83 0 56.48
5 INT342383 Binding of Srp14 and Best1 1 0.00 0.56 0 29.12
6 INT342386 Binding of CALCR and Best1 1 0.01 0.96 0 29.12
7 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
8 INT311963 Ifx Negative_regulation of FBN1 1 0.00 0.44 0.5 5.00
9 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48 5.00
10 INT311950 FBN1 Positive_regulation of Gene_expression of PGF 1 0.00 0.15 0.26 5.00
11 INT316598 Pth Regulation of Fgf23 1 0.10 0.28 0.03 5.00
12 INT342385 Positive_regulation of Binding of Lrp5 and Vdr 1 0.53 0.98 0 5.00
13 INT342378 Binding of Vdr and Best1 1 0.05 0.4 0 5.00
14 INT342381 Binding of Lrp5 and Vdr 1 0.55 0.97 0 5.00
15 INT316600 Binding of Acp5 and Matk 1 0.01 0 0 5.00
16 INT254434 Binding of Lrp5 and Best1 3 0.29 2.53 0 5.00
17 INT316599 Positive_regulation of Binding of Acp5 and Matk 1 0.01 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Femoral Neck Fractures. They are ordered first by their pain relevance and then by number of times they were reported in Femoral Neck Fractures. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT100912 Regulation of Kdm5d 52 0.32 20.39 4.72 99.50
2 INT403 Localization of Trh 241 0.81 28.55 81.45 96.96
3 INT163545 Gene_expression of PDGFRB 39 0.78 25.5 2.2 94.48
4 INT238431 Binding of SRA1 8 0.37 2.53 0.25 93.60
5 INT1377 Positive_regulation of Trh 172 0.70 40.55 69.83 93.52
6 INT2323 Gene_expression of Trh 146 0.78 29.92 49.5 92.28
7 INT215302 Gene_expression of PQBP1 15 0.53 3.93 0.31 92.08
8 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 89.84
9 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 88.64
10 INT265794 Regulation of SRA1 3 0.23 3.05 0.35 84.76
11 INT80419 Gene_expression of Kdm5d 50 0.62 22.49 6.1 83.56
12 INT30039 Negative_regulation of HAL 7 0.42 4.32 1.61 81.44
13 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 81.24
14 INT171998 Binding of DMD 58 0.47 38.13 3.35 78.08
15 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 75.12
16 INT546 Binding of ALB 311 0.48 85.98 60.14 75.00
17 INT178763 Binding of HHIP 37 0.08 6.3 5.29 72.88
18 INT39624 Binding of DHS 3 0.31 1.8 0.41 72.64
19 INT276086 Regulation of Positive_regulation of GBD3 1 0.09 1.3 0.04 72.32
20 INT276085 Positive_regulation of GBD3 1 0.10 1.29 0.04 71.84
21 INT5609 Regulation of Ifx 6 0.60 5.73 3.5 67.52
22 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 66.40
23 INT180149 Positive_regulation of SRA1 7 0.40 2.65 0.65 65.64
24 INT72676 Gene_expression of APOA1 34 0.75 34.15 1.67 65.40
25 INT178037 Gene_expression of Del(7)Tyr<c-23DVT>-p 18 0.22 23.44 4.07 63.52
26 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 63.04
27 INT126672 Binding of Bcar1 7 0.20 2.67 0.98 61.48
28 INT58288 Positive_regulation of Gene_expression of Crp 83 0.61 82.23 23.7 60.16
29 INT84685 Regulation of BCL2 67 0.60 72.96 6.65 56.64
30 INT254426 Gene_expression of Lrp5 5 0.67 3.28 0.06 39.12
31 INT102074 Positive_regulation of Gene_expression of APC 20 0.50 13.66 1.1 37.36
32 INT57057 Gene_expression of APC 131 0.78 122.24 8.7 36.48
33 INT225689 Gene_expression of SMS 10 0.65 5.66 0.03 33.36
34 INT262107 Binding of Vdr 9 0.48 6.56 0.71 32.00
35 INT183374 Binding of Dntt 2 0.30 5.03 0.8 30.92
36 INT103298 Binding of CALCR 5 0.47 6.03 2.15 29.12
37 INT211971 Binding of Best1 16 0.22 7.73 0.33 29.12
38 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 28.88
39 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 28.88
40 INT262063 Localization of Vdr 3 0.75 1.76 0.33 26.72
41 INT316585 Regulation of Gene_expression of Hopx 1 0.01 0.63 0 16.56
42 INT316584 Gene_expression of Hopx 1 0.02 2 0 16.16
43 INT142719 Binding of Col1a1 7 0.34 5.83 1.47 15.36
44 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 13.68
45 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 13.36
46 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 11.28
47 INT211970 Negative_regulation of Best1 49 0.14 37.33 2.32 7.44
48 INT133695 Transcription of Ibsp 4 0.36 5.7 1.32 6.16
49 INT176513 Transcription of Spp1 5 0.63 4.32 0.67 6.16
50 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
51 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 5.00
52 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 5.00
53 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
54 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
55 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
56 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
57 INT7362 Gene_expression of Sst 185 0.78 41.73 111.37 5.00
58 INT2122 Negative_regulation of Localization of Gnrh1 226 0.59 26.92 92.04 5.00
59 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 5.00
60 INT4631 Positive_regulation of Sst 127 0.70 17.37 83.29 5.00
61 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
62 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
63 INT11937 Localization of Il6 228 0.81 139.83 64.39 5.00
64 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
65 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 5.00
66 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 5.00
67 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
68 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51 5.00
69 INT132161 Gene_expression of MTX1 48 0.58 26.55 32.32 5.00
70 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
71 INT86437 Binding of IL6 154 0.48 121.22 29.3 5.00
72 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
73 INT1765 Positive_regulation of Gene_expression of PTGER2 140 0.51 68.68 27 5.00
74 INT151758 Gene_expression of PYCARD 91 0.63 14.54 24.27 5.00
75 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31 5.00
76 INT171820 Localization of Fig4 144 0.65 27.38 20.88 5.00
77 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78 5.00
78 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 5.00
79 INT170033 Positive_regulation of Gene_expression of Fig4 59 0.43 20.99 16.69 5.00
80 INT197375 Gene_expression of Car1 84 0.65 16.46 16.45 5.00
81 INT912 Localization of FSHR 91 0.79 23.61 15.58 5.00
82 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 5.00
83 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15 5.00
84 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 5.00
85 INT88544 Gene_expression of MMRN1 102 0.75 68.8 14.55 5.00
86 INT55168 Binding of NFKB1 55 0.48 22.94 13.15 5.00
87 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02 5.00
88 INT54763 Binding of Il6 82 0.48 63.27 12.89 5.00
89 INT125477 Gene_expression of HHIP 91 0.78 31.18 12.57 5.00
90 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 5.00
91 INT1763 Regulation of Gene_expression of PTGER2 43 0.36 23.98 10.95 5.00
92 INT103554 Positive_regulation of MTX1 19 0.45 11.23 10 5.00
93 INT157941 Gene_expression of IL-17 65 0.65 20.39 9.89 5.00
94 INT182320 Binding of MTX1 14 0.18 8.5 7.65 5.00
95 INT122901 Positive_regulation of Spp1 67 0.67 58.03 7.49 5.00
96 INT50212 Gene_expression of Ifx 33 0.75 32.17 7.26 5.00
97 INT85923 Positive_regulation of CREM 25 0.67 7.03 6.53 5.00
98 INT39047 Gene_expression of PGF 34 0.78 17.48 6 5.00
99 INT38556 Gene_expression of DBT 47 0.50 12.52 5.6 5.00
100 INT22943 Positive_regulation of Positive_regulation of Gpt 23 0.47 16.09 5.55 5.00
101 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45 5.00
102 INT125478 Localization of HHIP 32 0.80 3.43 4.68 5.00
103 INT22145 Binding of Sugt1 16 0.13 8.31 4.37 5.00
104 INT20981 Binding of HRAS 42 0.48 24.49 4.23 5.00
105 INT156137 Gene_expression of Col1a2 28 0.73 13.3 3.99 5.00
106 INT80175 Positive_regulation of Gene_expression of HRAS 24 0.67 14.69 3.97 5.00
107 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95 5.00
108 INT125479 Positive_regulation of HHIP 38 0.44 12.39 3.75 5.00
109 INT98944 Gene_expression of ACTA2 14 0.59 11 3.7 5.00
110 INT90406 Gene_expression of IL6R 27 0.38 15.74 3.64 5.00
111 INT174816 Binding of IL6R 14 0.09 11.26 3.63 5.00
112 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52 5.00
113 INT1646 Negative_regulation of Localization of FSHR 17 0.58 7.36 3.46 5.00
114 INT113029 Negative_regulation of Myo5a 7 0.48 0.97 2.95 5.00
115 INT45575 Gene_expression of Ibsp 8 0.50 11.83 2.85 5.00
116 INT14448 Localization of COL5A2 34 0.67 17.35 2.85 5.00
117 INT160633 Gene_expression of Vdr 21 0.77 10.01 2.73 5.00
118 INT50268 Gene_expression of FBN1 13 0.65 10.73 2.72 5.00
119 INT61465 Gene_expression of Acp5 22 0.75 7.06 2.55 5.00
120 INT136093 Regulation of FBN1 10 0.14 4.39 2.52 5.00
121 INT157943 Positive_regulation of IL-17 10 0.58 6.65 2.43 5.00
122 INT52409 Positive_regulation of FBN1 8 0.40 7.28 2.41 5.00
123 INT232414 Negative_regulation of Ifx 6 0.42 3.28 2.26 5.00
124 INT158123 Negative_regulation of Gene_expression of COL5A2 19 0.46 15.27 2.23 5.00
125 INT126513 Gene_expression of Col1a1 23 0.75 10.92 2.18 5.00
126 INT42369 Localization of Ibsp 6 0.62 2.51 2.17 5.00
127 INT125480 Regulation of HHIP 17 0.38 6.16 2.16 5.00
128 INT175655 Regulation of MMRN1 16 0.12 9.96 2.12 5.00
129 INT174541 Positive_regulation of Gene_expression of COL5A2 18 0.36 14.17 2.12 5.00
130 INT113717 Negative_regulation of Gene_expression of COL1A1 21 0.41 6.14 2.01 5.00
131 INT176510 Binding of Spp1 21 0.42 22.1 2 5.00
132 INT213431 Positive_regulation of Gene_expression of MMRN1 15 0.24 9.91 1.96 5.00
133 INT176516 Localization of Spp1 28 0.76 19.39 1.9 5.00
134 INT102694 Localization of CREM 4 0.27 1.6 1.8 5.00
135 INT179222 Gene_expression of AMIGO2 7 0.66 7.68 1.77 5.00
136 INT139317 Negative_regulation of Col1a2 8 0.41 7.17 1.54 5.00
137 INT184206 Protein_catabolism of HRAS 22 0.66 7.86 1.46 5.00
138 INT243655 Positive_regulation of Gene_expression of IL-17 11 0.58 3.06 1.45 5.00
139 INT36330 Positive_regulation of Positive_regulation of GOT1 4 0.32 4.42 1.26 5.00
140 INT35103 Positive_regulation of Positive_regulation of SLC17A5 5 0.12 7.51 1.25 5.00
141 INT45576 Positive_regulation of Ibsp 4 0.41 3.41 1.21 5.00
142 INT222991 Negative_regulation of Gene_expression of MMRN1 10 0.13 4.39 1.14 5.00
143 INT156614 Regulation of Gene_expression of COL1A1 6 0.33 2.51 0.99 5.00
144 INT197365 Localization of Car1 7 0.73 1.11 0.94 5.00
145 INT88600 Positive_regulation of Binding of NFKB1 9 0.59 2.1 0.88 5.00
146 INT134654 Localization of CALCR 5 0.39 3.21 0.85 5.00
147 INT42370 Negative_regulation of Ibsp 3 0.38 0.68 0.81 5.00
148 INT187709 Regulation of Gene_expression of DBT 3 0.04 0.63 0.8 5.00
149 INT192156 Negative_regulation of Col1a1 6 0.39 3.92 0.8 5.00
150 INT130797 Gene_expression of Fgf23 6 0.66 4.73 0.77 5.00
151 INT176528 Regulation of Spp1 9 0.45 9.05 0.77 5.00
152 INT39820 Gene_expression of CALCR 16 0.37 4.96 0.74 5.00
153 INT44612 Positive_regulation of APOE 16 0.67 5.73 0.72 5.00
154 INT248470 Gene_expression of Ighmbp2 5 0.75 3.32 0.68 5.00
155 INT262060 Positive_regulation of Vdr 8 0.58 2.84 0.67 5.00
156 INT175580 Localization of APOE 10 0.76 18.84 0.65 5.00
157 INT260859 Negative_regulation of Binding of IL6R 1 0.06 1.08 0.38 5.00
158 INT121141 Transcription of Spp1 6 0.34 5.02 0.38 5.00
159 INT257288 Regulation of Gene_expression of COL5A2 7 0.21 2.52 0.36 5.00
160 INT130739 Binding of Col1a2 2 0.35 2.38 0.34 5.00
161 INT297804 Regulation of Lrp5 6 0.60 2.31 0.27 5.00
162 INT157409 Negative_regulation of Fgf23 3 0.50 3.21 0.27 5.00
163 INT254427 Binding of Lrp5 10 0.48 5.43 0.26 5.00
164 INT180972 Transcription of MMRN1 2 0.11 0.17 0.24 5.00
165 INT311955 Negative_regulation of Transcription of MMRN1 1 0.07 0.1 0.24 5.00
166 INT10425 Positive_regulation of Myo5a 5 0.66 0.41 0.21 5.00
167 INT88734 Regulation of CREM 10 0.27 2.01 0.21 5.00
168 INT130798 Positive_regulation of Gene_expression of Fgf23 2 0.59 1.12 0.2 5.00
169 INT254429 Negative_regulation of Lrp5 4 0.57 1.95 0.18 5.00
170 INT135975 Binding of Ibsp 2 0.31 0.31 0.15 5.00
171 INT70262 Gene_expression of Pth 8 0.66 5.64 0.12 5.00
172 INT72901 Negative_regulation of Il1rl1 2 0.27 0.59 0.06 5.00
173 INT316587 Gene_expression of Matk 1 0.07 1.53 0.06 5.00
174 INT316595 Transcription of Fgf23 1 0.61 0.44 0.04 5.00
175 INT174145 Positive_regulation of EBM 5 0.44 0.49 0.04 5.00
176 INT316589 Negative_regulation of Transcription of Fgf23 1 0.50 0.44 0.04 5.00
177 INT262079 Negative_regulation of Vdr 2 0.42 0.71 0.04 5.00
178 INT316576 Transcription of Acp5 1 0.11 0.79 0.03 5.00
179 INT316588 Positive_regulation of Fgf23 1 0.43 0.29 0.03 5.00
180 INT316593 Transcription of Matk 1 0.06 0.79 0.03 5.00
181 INT316586 Regulation of Transcription of Ibsp 1 0.23 0.16 0 5.00
182 INT316591 Regulation of Gene_expression of Matk 1 0.04 0.06 0 5.00
183 INT316594 Negative_regulation of Binding of Ibsp 1 0.21 0.06 0 5.00
184 INT316596 Regulation of Transcription of Matk 1 0.03 0.16 0 5.00
185 INT316578 Regulation of Transcription of Spp1 1 0.09 0.16 0 5.00
186 INT316580 Binding of Acp5 1 0.06 0 0 5.00
187 INT316577 Positive_regulation of Binding of Acp5 1 0.08 0 0 5.00
188 INT316592 Negative_regulation of Binding of Matk 1 0.04 0.06 0 5.00
189 INT316597 Binding of Matk 1 0.03 0.06 0 5.00
190 INT316590 Positive_regulation of Binding of Matk 1 0.04 0 0 5.00
191 INT316579 Negative_regulation of Binding of Spp1 1 0.09 0.06 0 5.00
192 INT342375 Positive_regulation of Binding of Lrp5 1 0.46 0.85 0 5.00
193 INT342374 Negative_regulation of Gene_expression of Pth 1 0.15 0.94 0 5.00
194 INT342376 Positive_regulation of Binding of Vdr 1 0.46 0.86 0 5.00
195 INT342269 Regulation of PLAGL1 1 0.44 0 0 5.00
196 INT316575 Regulation of Transcription of Acp5 1 0.06 0.16 0 5.00
197 INT61467 Regulation of Gene_expression of Acp5 1 0.59 0.06 0 5.00
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