D:Fetal Diseases

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Disease Term
Synonyms Disease Fetal, Diseases Fetal, Embryopathies, EMBRYOPATHY, FETAL DISEASE
Documents 28
Hot Single Events 8
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Fetal Diseases. They are ordered first by their relevance to Fetal Diseases and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT253193 Ros1 Regulation of Parp1 1 0.01 0.57 0.05 62.84
2 INT186240 Binding of AGRP and SCN5A 2 0.13 1.19 0.1 7.36
3 INT186246 Binding of CAT and SCN5A 1 0.03 0.47 0.1 7.36
4 INT186242 Binding of ALB and SCN5A 1 0.04 0.36 0.1 7.36
5 INT186245 Binding of AGRP and CAT 1 0.02 0.53 0.1 6.96
6 INT186244 Binding of AGRP and ALB 1 0.03 0.53 0.1 6.96
7 INT223962 Tnf Negative_regulation of Gene_expression of Bglap 1 0.21 1.21 0.32 5.00
8 INT223964 Tnf Negative_regulation of Bglap 1 0.21 1.2 0.32 5.00
9 INT223965 Binding of AMY2A and Bglap 1 0.05 1.5 0.28 5.00
10 INT223963 Binding of Bglap and Runx2 1 0.14 1.74 0.13 5.00
11 INT186243 IL36RN Positive_regulation of B4GALNT1 1 0.00 0.43 0.12 5.00
12 INT186249 Binding of ROS1 and SCN5A 1 0.09 0.73 0.03 5.00
13 INT186248 NR5A1 Positive_regulation of Transcription of STAR 1 0.01 0.21 0 5.00
14 INT186239 Binding of ROS1 and Positive_regulation of PDE2A 1 0.00 0 0 5.00
15 INT186241 Gene_expression of ROS1 Positive_regulation of PDE2A 1 0.00 0 0 5.00
16 INT175246 Binding of F13A1 and SH2B2 1 0.00 2.24 0 5.00
17 INT186247 CGA Regulation of Gene_expression of SOD1 1 0.01 0.35 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Fetal Diseases. They are ordered first by their pain relevance and then by number of times they were reported in Fetal Diseases. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT223959 Localization of Bglap 10 0.77 11.25 1.74 98.84
2 INT110599 Gene_expression of Bglap 49 0.74 41.23 6.97 96.44
3 INT223948 Negative_regulation of Gene_expression of Bglap 1 0.56 6.49 0.44 96.44
4 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27 92.76
5 INT184301 Negative_regulation of Bglap 16 0.56 11.22 1.22 87.96
6 INT110569 Gene_expression of XDH 31 0.75 18.35 1.34 81.12
7 INT48766 Regulation of NOS1 73 0.61 37.01 24.59 80.72
8 INT69439 Regulation of ROS1 46 0.45 31.22 6.94 80.72
9 INT87340 Negative_regulation of BCAR1 8 0.38 6.96 2.63 78.52
10 INT183819 Negative_regulation of Positive_regulation of BCAR1 1 0.38 2.04 0.05 78.52
11 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23 78.12
12 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 73.20
13 INT112003 Localization of ROS1 94 0.73 66.32 12.16 73.20
14 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68 73.16
15 INT99091 Regulation of AR 70 0.45 31.68 5.05 73.12
16 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 72.76
17 INT82932 Transcription of AR 14 0.67 5.75 1.34 72.48
18 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 67.04
19 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 63.88
20 INT123813 Positive_regulation of Parp1 74 0.70 65.36 8.56 59.40
21 INT3404 Binding of BCAR1 10 0.33 7.97 1.33 54.12
22 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 49.60
23 INT223949 Transcription of Bglap 1 0.68 19.96 3.98 46.96
24 INT176270 Regulation of p53-ps 2 0.30 0.79 0.09 44.84
25 INT253175 Regulation of Positive_regulation of Parp1 2 0.52 0.97 0.08 44.84
26 INT253179 Regulation of Gene_expression of p53-ps 1 0.30 0.46 0.05 44.84
27 INT253176 Regulation of Gene_expression of Parp1 2 0.23 0.61 0.05 44.84
28 INT68792 Gene_expression of p53-ps 14 0.75 6.81 2.47 44.20
29 INT123815 Gene_expression of Parp1 42 0.67 27.82 3.02 42.80
30 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 41.96
31 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18 41.64
32 INT223958 Positive_regulation of Transcription of Bglap 1 0.66 6.57 1.19 39.60
33 INT158025 Regulation of Bglap 6 0.60 7.03 1.11 39.60
34 INT223960 Positive_regulation of Transcription of AMY2A 1 0.08 4.88 1.07 38.68
35 INT223955 Positive_regulation of Transcription of Amy2a1 1 0.49 1.77 0.41 38.68
36 INT223950 Transcription of Amy2a1 2 0.69 1.98 0.41 38.12
37 INT55597 Negative_regulation of Gpx1 59 0.55 28.3 8.83 38.04
38 INT223961 Transcription of AMY2A 1 0.11 4.83 1.06 37.64
39 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 37.28
40 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 37.28
41 INT186257 Positive_regulation of Transcription of ROS1 2 0.34 0.1 0.03 37.28
42 INT253182 Positive_regulation of Positive_regulation of Bmp4 1 0.45 0.58 0.04 37.12
43 INT196030 Positive_regulation of Bmp4 6 0.62 2.55 0.04 37.12
44 INT186256 Transcription of ROS1 4 0.39 2.37 0.25 36.88
45 INT223954 Negative_regulation of Transcription of Bglap 1 0.41 2.7 0.49 35.84
46 INT48253 Positive_regulation of AMY2A 8 0.59 3.86 1.79 31.84
47 INT184303 Positive_regulation of Bglap 16 0.66 8.66 1.25 31.84
48 INT61513 Positive_regulation of Gpx1 71 0.64 37.91 17.07 31.24
49 INT213965 Gene_expression of rsm1 7 0.54 4.18 1.29 30.96
50 INT223956 Regulation of Transcription of Bglap 1 0.43 1.4 0.44 25.32
51 INT159382 Gene_expression of Prdx4 3 0.18 2.33 0.1 23.68
52 INT253178 Negative_regulation of Gene_expression of Prdx4 1 0.02 0.64 0.05 23.68
53 INT15506 Localization of Cp 11 0.80 4.26 1.9 21.76
54 INT172808 Positive_regulation of Positive_regulation of ROS1 35 0.40 31.39 2.27 20.36
55 INT50392 Regulation of Ret 6 0.54 3.51 2.22 18.00
56 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 15.76
57 INT253183 Negative_regulation of Shh 8 0.55 2.13 0.12 15.08
58 INT253187 Negative_regulation of Transcription of Shh 1 0.41 0.55 0.03 12.56
59 INT253181 Transcription of Shh 1 0.68 0.54 0.03 11.00
60 INT253177 Negative_regulation of Gene_expression of Shh 2 0.55 0.63 0.16 8.88
61 INT144973 Gene_expression of Shh 9 0.77 4.32 1.96 8.48
62 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 5.00
63 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
64 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 5.00
65 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 5.00
66 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 5.00
67 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
68 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
69 INT1793 Localization of CGA 379 0.81 67.38 114.69 5.00
70 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
71 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
72 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
73 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 5.00
74 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 5.00
75 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18 5.00
76 INT7035 Regulation of CGA 87 0.45 29.04 28.45 5.00
77 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 5.00
78 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 5.00
79 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 5.00
80 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 5.00
81 INT70504 Regulation of Gene_expression of NOS1 30 0.51 21.72 21.72 5.00
82 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
83 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 5.00
84 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03 5.00
85 INT12950 Gene_expression of Cat 85 0.75 35.94 15.76 5.00
86 INT74449 Positive_regulation of B4GALNT1 53 0.30 34.49 14.96 5.00
87 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 5.00
88 INT73594 Positive_regulation of Gene_expression of ISYNA1 61 0.55 31.35 13.45 5.00
89 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 5.00
90 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48 5.00
91 INT69436 Negative_regulation of Gene_expression of ROS1 81 0.38 46.58 12.22 5.00
92 INT41313 Gene_expression of Gpx1 68 0.78 34.24 11.77 5.00
93 INT50933 Transcription of Il6 38 0.72 24.31 11.58 5.00
94 INT3845 Gene_expression of GSR 79 0.76 44.69 11.19 5.00
95 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 5.00
96 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 5.00
97 INT62895 Gene_expression of NOSTRIN 51 0.75 28.8 10.68 5.00
98 INT22132 Positive_regulation of CAT 41 0.67 18.64 10.67 5.00
99 INT86361 Positive_regulation of Positive_regulation of NOS1 39 0.53 18.93 10.42 5.00
100 INT94784 Binding of ROS1 113 0.40 71.57 10.26 5.00
101 INT3846 Positive_regulation of GSR 60 0.50 35.16 9.37 5.00
102 INT52924 Negative_regulation of GSR 49 0.58 28.08 9.28 5.00
103 INT55342 Negative_regulation of Gene_expression of Ros1 49 0.37 31.62 8.93 5.00
104 INT48908 Transcription of NOS1 27 0.55 13.46 8.39 5.00
105 INT124297 Gene_expression of Sod2 112 0.77 65.65 7.64 5.00
106 INT6906 Negative_regulation of SCN5A 64 0.43 20.64 7.3 5.00
107 INT35584 Binding of ACLY 22 0.35 31.78 7.17 5.00
108 INT79062 Gene_expression of B4GALNT1 42 0.14 18.89 6.98 5.00
109 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 5.00
110 INT29561 Binding of GSTM1 35 0.48 25.86 6.24 5.00
111 INT91159 Negative_regulation of Ros1 35 0.44 26.12 5.97 5.00
112 INT48911 Binding of NOS1 24 0.40 11.21 5.89 5.00
113 INT91754 Gene_expression of Cp 42 0.77 21.97 5.38 5.00
114 INT35536 Negative_regulation of CAT 26 0.57 14.39 5.38 5.00
115 INT30209 Localization of SCN5A 24 0.72 7.95 5.35 5.00
116 INT81796 Binding of AGRP 62 0.36 37.19 5.3 5.00
117 INT5411 Positive_regulation of G6pd 20 0.70 4.74 5.11 5.00
118 INT187295 Gene_expression of Serpinb1a 6 0.58 13.73 5.05 5.00
119 INT111594 Positive_regulation of Gene_expression of NOSTRIN 20 0.32 8.69 5 5.00
120 INT37661 Negative_regulation of SERPINC1 48 0.59 38.6 4.77 5.00
121 INT9842 Binding of F2 36 0.47 22.79 4.42 5.00
122 INT102187 Gene_expression of SH2B2 23 0.59 26.54 4.39 5.00
123 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22 5.00
124 INT44323 Positive_regulation of F8 32 0.60 24.88 3.89 5.00
125 INT53584 Regulation of Gpx1 19 0.62 14.38 3.48 5.00
126 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 5.00
127 INT175262 Binding of SH2B2 18 0.36 22.85 3.18 5.00
128 INT140555 Positive_regulation of Localization of ROS1 29 0.55 23.82 3.14 5.00
129 INT61791 Positive_regulation of SH2B2 9 0.50 8.36 2.99 5.00
130 INT14447 Localization of F2 20 0.79 12.77 2.67 5.00
131 INT142120 Gene_expression of Runx2 45 0.77 15.76 2.55 5.00
132 INT71933 Positive_regulation of Gene_expression of F2 19 0.56 14.24 2.53 5.00
133 INT22129 Positive_regulation of Gene_expression of CAT 11 0.67 4.23 2.37 5.00
134 INT100886 Gene_expression of GCLC 16 0.76 5.63 2.29 5.00
135 INT96856 Localization of NOSTRIN 8 0.49 6.39 2.19 5.00
136 INT11183 Negative_regulation of SH2B2 4 0.34 6.99 2.12 5.00
137 INT82166 Regulation of NOS3 14 0.54 7.57 2.08 5.00
138 INT96764 Positive_regulation of Gene_expression of SOD1 36 0.61 16.55 1.99 5.00
139 INT2982 Positive_regulation of Gene_expression of CGA 17 0.59 9.08 1.99 5.00
140 INT64709 Gene_expression of VTN 11 0.67 11.01 1.97 5.00
141 INT34864 Binding of Cp 23 0.47 5.17 1.78 5.00
142 INT94848 Negative_regulation of Gene_expression of Gpx1 11 0.30 4.91 1.7 5.00
143 INT117330 Negative_regulation of Binding of ROS1 13 0.37 8.33 1.67 5.00
144 INT124299 Negative_regulation of Gene_expression of Sod2 15 0.53 13.8 1.51 5.00
145 INT117101 Gene_expression of Sod1 18 0.67 7.93 1.47 5.00
146 INT91863 Negative_regulation of Gene_expression of NOS3 13 0.51 9.43 1.34 5.00
147 INT42116 Positive_regulation of ME1 5 0.05 1.56 1.33 5.00
148 INT184314 Regulation of Gene_expression of Bglap 6 0.59 7.11 1.16 5.00
149 INT253191 Positive_regulation of Gene_expression of Shh 2 0.66 2.57 1.14 5.00
150 INT100892 Positive_regulation of GCLC 8 0.68 3.44 1.08 5.00
151 INT15527 Gene_expression of FFAR1 19 0.61 11.15 1.08 5.00
152 INT186251 Negative_regulation of Gene_expression of B4GALNT1 5 0.07 1.84 1.07 5.00
153 INT183820 Regulation of BCAR1 4 0.39 3.27 1.06 5.00
154 INT159543 Localization of SOD1 29 0.75 8.62 1.06 5.00
155 INT153327 Gene_expression of Aspscr1 5 0.57 3.28 0.91 5.00
156 INT124300 Negative_regulation of Sod2 17 0.45 12.54 0.9 5.00
157 INT104908 Binding of B4GALNT1 7 0.05 4.62 0.82 5.00
158 INT135836 Negative_regulation of Sod1 5 0.25 1.62 0.82 5.00
159 INT162803 Regulation of F5 3 0.44 3.68 0.81 5.00
160 INT170772 Negative_regulation of Gene_expression of GSR 8 0.41 3.05 0.7 5.00
161 INT142123 Positive_regulation of Gene_expression of Runx2 17 0.64 4.81 0.65 5.00
162 INT70530 Binding of NPR1 3 0.17 0.71 0.65 5.00
163 INT9809 Positive_regulation of Mdn1 2 0.06 0.33 0.65 5.00
164 INT81799 Negative_regulation of Binding of AGRP 5 0.42 1.13 0.63 5.00
165 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63 5.00
166 INT174274 Positive_regulation of Localization of NOSTRIN 2 0.09 2.35 0.58 5.00
167 INT186260 Positive_regulation of Binding of B4GALNT1 1 0.06 0.93 0.56 5.00
168 INT84180 Binding of F5 22 0.48 18.6 0.49 5.00
169 INT223952 Regulation of Gene_expression of Cp 2 0.08 1.36 0.45 5.00
170 INT180688 Transcription of Bmp4 3 0.58 0.35 0.41 5.00
171 INT180702 Positive_regulation of Transcription of Bmp4 3 0.42 0.35 0.41 5.00
172 INT7691 Negative_regulation of Rnase1 7 0.43 0.41 0.38 5.00
173 INT127208 Regulation of Gpx1 3 0.48 1.34 0.38 5.00
174 INT159542 Localization of SOD2 5 0.80 1.91 0.36 5.00
175 INT84981 Negative_regulation of Gene_expression of CAT 3 0.41 0.35 0.35 5.00
176 INT223947 Localization of Panc1 2 0.15 1.73 0.33 5.00
177 INT140879 Gene_expression of Akr1b1 2 0.46 1.86 0.26 5.00
178 INT129399 Transcription of SOD1 6 0.66 3.08 0.25 5.00
179 INT175260 Negative_regulation of Gene_expression of SH2B2 2 0.25 4.41 0.21 5.00
180 INT238309 Negative_regulation of Gene_expression of Sod1 3 0.38 1.09 0.2 5.00
181 INT223946 Positive_regulation of Localization of Bglap 1 0.48 1.25 0.17 5.00
182 INT114965 Negative_regulation of Gpx1 13 0.53 6.82 0.14 5.00
183 INT253190 Localization of Shh 2 0.77 1.06 0.13 5.00
184 INT223953 Localization of Aspscr1 1 0.10 1.05 0.13 5.00
185 INT110568 Positive_regulation of Gene_expression of XDH 7 0.49 5.14 0.09 5.00
186 INT223957 Negative_regulation of Regulation of Bglap 1 0.41 1.47 0.08 5.00
187 INT186259 Gene_expression of NR5A1 2 0.64 2.19 0.05 5.00
188 INT183818 Positive_regulation of MKKS 1 0.01 1.82 0.05 5.00
189 INT186261 Gene_expression of ME1 3 0.10 2.87 0 5.00
190 INT114964 Negative_regulation of Gene_expression of Gpx1 2 0.53 2.39 0 5.00
191 INT217630 Negative_regulation of Transcription of Gpx1 2 0.41 1.07 0 5.00
192 INT253189 Regulation of Gene_expression of Prdx4 1 0.01 0.6 0 5.00
193 INT253186 Positive_regulation of Regulation of Gpx1 1 0.42 0.75 0 5.00
194 INT266504 Negative_regulation of rsm1 1 0.30 0.53 0 5.00
195 INT175261 Positive_regulation of Negative_regulation of VTN 1 0.02 0.77 0 5.00
196 INT266508 Binding of rsm1 2 0.25 0.89 0 5.00
197 INT253188 Localization of Gpx1 1 0.73 1.31 0 5.00
198 INT266505 Protein_catabolism of rsm1 1 0.62 0.85 0 5.00
199 INT253192 Gene_expression of Gpx2 1 0.44 0.9 0 5.00
200 INT186254 Transcription of STAR 1 0.02 0.2 0 5.00
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